IMPLANTABLE MICRO-ELECTROCHEMICAL CELL

A disease management system including an microelectrochemical cell configured to be implanted into a patient. The microelectrochemical cell may include a tube which may include at least one sidewall, a closed end configured to be implanted in the patient, and open end configured to receive a feedthrough for at least one electrode lead. The microelectrochemical cell may further include a fluid medium in fluid communication with bodily fluid, an analyte sensor configured to measure at least one analyte within the bodily fluid, and at least one electrical connection to the analyte sensor at the feedthrough.

WEARABLE PHYSIOLOGICAL MONITORING DEVICES

A wearable device including at least one sensor configured to sense a physiological parameter of a user. The wearable device including a base housing and a removable housing attachable to the base housing. The base housing and the removable housing portions each including a battery and an electronic subsystem in communication with each other. The battery of the removable housing portion charges the battery of the base housing portion when the removable housing portion is attached to the base housing portion. A second embodiment includes two or more fitness trackers each having an enclosure. The enclosures of the two or more fitness trackers having complimentary shapes that form a unified enclosure when the enclosures are placed adjacently. In a third embodiment, a wearable device includes a first screen display and a second screen display. The second screen display is transparent in at least one operational mode of the wearable device.

STACKED ELECTRONIC DEVICES

Disclosed is a stacked electronic device including a first and second bonded structure. The first bonded structure includes a first and second semiconductor element, each having a semiconductor region, a front side on one side of the semiconductor region including active circuitry, and a back side opposite the front side. The front side of the first semiconductor element is bonded and electrically connected to the front side of the second semiconductor element. The second bonded structure includes a third and fourth semiconductor element, which can include similar components to the first and second semiconductor elements. The front side of the third semiconductor element is bonded and electrically connected to the front side of the fourth semiconductor element. The back side of the second semiconductor element is bonded and electrically connected to the back side of the third semiconductor element.

PROFILING OF BIOLOGICAL ANALYTES WITH SPATIALLY BARCODED OLIGONUCLEOTIDE ARRAYS

This disclosure relates to methods for spatial profiling of analytes present in a biological sample. Also provided are methods for using spatially barcoded substrates to detect a biological analyte in a cell culture, an organism, and organoid. Also provided are methods for using spatially barcoded substrates to detect the temporal profile of a biological analyte.

Methods for spatial analysis using targeted RNA depletion

Provided herein are methods for spatial analysis using targeted RNA depletion.

HIGH THROUGHPUT EPITOPE IDENTIFICATION AND T CELL RECEPTOR SPECIFICITY DETERMINATION USING LOADABLE DETECTION MOLECULES

The present invention relates to detection of interactions between antigenic peptides and binding partners, such as T cell receptors (TCR) and antigenic peptide responsive T cells. In particular, the present invention relates to the provision of loadable detection molecules with peptide-free MHC molecules utilized for high throughput epitope identification and TCR specificity determination.

METHOD OF HUB COMMUNICATION WITH SURGICAL INSTRUMENT SYSTEMS

A method for adjusting the operation of a surgical suturing instrument using machine learning in a surgical suite is disclosed. The method comprises gathering data during surgical procedures, wherein the surgical procedures include the use of a surgical suturing instrument comprising a suturing needle configured to be mechanically advanced through a suturing stroke, analyzing the gathered data to determine an appropriate operational adjustment of the surgical suturing instrument, and adjusting the operation of the surgical suturing instrument to improve the operation of the surgical suturing instrument.

FLUID COLLECTION ASSEMBLIES INCLUDING A FLUID IMPERMEABLE BARRIER HAVING A SUMP AND A BASE

Embodiments disclosed herein are directed to fluid collection assemblies including a fluid impermeable barrier having a sump and a base. An example fluid collection assembly includes a fluid impermeable barrier. The fluid impermeable barrier includes a sump and a base. For example, the sump may protrude outwardly from the base. The sump defines an opening and a chamber. The fluid collection assembly may include at least one porous material disposed in the chamber that at least partially covers the opening, such as a fluid permeable membrane extending across at least a portion of the opening and a support disposed in the chamber. The fluid collection assembly may also include an adhesive layer disposed on the base that is configured to secure the rest of the fluid collection assembly to at least a portion of a pubic region of an individual. Further, the fluid collection assembly may include a fluid outlet.

Access points, station and corresponding methods

A first access point comprises circuitry configured to perform a sounding procedure with one or more first stations associated with the first access point and configured to communicate with the first access point over a respective channel to determine resource unit allocation and beamforming configuration for use in subsequent communication with respective first stations, and to transmit a training data unit containing signaling information related to the determined resource unit allocation and related to the determined beamforming configuration, wherein the training data unit is transmitted with a beamforming configuration derived from the determined resource unit allocation and the determined beamforming configuration.

Combustion-gas supply system and method thereof, device equipped with turbine engine, and fracturing system

A combustion-gas supply system and a combustion-gas supply method thereof, a device equipped with a turbine engine, and a fracturing system are provided. The combustion-gas supply system includes a main pipeline and a multi-functional pipeline; the main pipeline includes a first sub-pipeline and a second sub-pipeline; the first sub-pipeline includes a first gas intake pipe, a first gas supply valve and a first gas outlet pipe arranged in sequence; the second sub-pipeline includes a combustion-gas supply valve and a gas supply pipe, the first gas outlet pipe is connected with the combustion-gas supply valve, the gas supply pipe is configured to be connected with a turbine engine, the multi-functional pipeline includes a second gas intake pipe, a second gas supply valve and a second gas outlet pipe arranged in sequence, and the second gas outlet pipe is communicated with the first gas outlet pipe.