20537 ⎘
Medicinal preparations containing organic active ingredients; Carbohydrates; Sugars; Derivatives thereof; Compounds having three or more nucleosides or nucleotides Double-stranded nucleic acids or oligonucleotides
Targeting Ligands For Therapeutic Compounds
#1802Polycation-Functionalized Nanoporous Silicon Carrier for Systemic Delivery of Gene Silencing Agents
#1803RAAV-based compositions and methods
#1804Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, Bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
#1805POLYMERIC NANOPARTICLES AND DERIVATIVES THEREOF FOR NUCLEIC ACID BINDING AND DELIVERY
#1806Bioreducible Poly (Beta-Amino Ester)s For siRNA Delivery
#1807PEPTIDE VACCINES AND DURVALUMAB FOR TREATING BREAST CANCER
#1808Methods and Pharmaceutical Compositions for Treating Lymphoid Malignancy
#1809Increasing ATOH1 life to drive sensorineural hair cell differentiation
#1810Anabolic Enhancers for Ameliorating Neurodegeneration
#1811COMPOSITIONS AND METHODS FOR PREVENTING BONE LOSS AND/OR STIMULATING BONE HEALING
#1812CNS TARGETING AAV VECTORS AND METHODS OF USE THEREOF
#1813CNS TARGETING AAV VECTORS AND METHODS OF USE THEREOF
#1814Use of Rad18 inhibitors in the treatment of tumors
#1815MicroRNA-198 as a tumor suppressor in ovarian cancer
#1816Vesicles comprising lectins expressed on the surface and methods of use thereof to deliver an agent to autophagic and apoptotic cells
#1817Lipid nanoparticle compositions and methods for mRNA delivery
#1818Nucleic acid-polypeptide compositions and uses thereof
#1819Nanocarriers and intracellular delivery of same
#1820Immunostimulant
#1821Topical formulations based on ionic species for skin treatment
#1822Particles with RNA cleaving nucleobase polymers and uses for managing inflammatory disorders
#1823Multi-functional particles and methods of using the same
#1824Carbohydrate conjugates as delivery agents for oligonucleotides
#1825SYSTEMIC IN VIVO DELIVERY OF OLIGONUCLEOTIDES
#1826MARKER FOR THE CLASSIFICATION, DIAGNOSIS AND TREATMENT OF SCOLIOSIS
#1827Methods of detecting DDR2 mutations
#1828MiR-127 agents for use in the treatment of renal fibrosis
#1829Methods for diagnosing and treating metastatic cancer
#1830Exon skipping compositions for treating muscular dystrophy
#1831Lipid nanoparticle compositions and methods for mRNA delivery
#1832MICRORNA 22 REGULATORS COMPOSITIONS AND METHODS AND USES THEREOF
#1833METHODS OF TREATING AGE RELATED DISORDERS
#1834Modulation of BCL11A for treatment of hemoglobinopathies
#1835Methods of Manipulating the Fate of Cells
#1836TLR9 TARGETED CYTOTOXIC AGENTS
#1837Lipids and compositions for the delivery of therapeutics
#1838Use of IAP inhibitor and oncolytic virus in preparation of anti-tumor drug
#1839Medicament for the treatment of acute liver failure
#1840MICRO-RNAS AND COMPOSITIONS COMPRISING SAME FOR THE TREATMENT AND DIAGNOSIS OF SEROTONIN-, ADRENALIN-, NORADRENALIN-, GLUTAMATE-, AND CORTICOTROPIN-RELEASING HORMONE- ASSOCIATED MEDICAL CONDITIONS
#1841Tumor suppressor TET1 and uses thereof
#1842Use of VCP inhibitor and oncolytic virus in the preparation of an anti-tumor drug
#1843Means and methods to treat dystonia
#1844Targeted nucleic acid conjugate compositions
#1845Combination therapy using inhibitors of human growth and differentiation factor 15 (GDF-15) and immune checkpoint blockers
#1846Compositions and methods for treating Huntington's disease
#1847Method of fixing and expressing physiologically active substance
#1848Targeting MicroRNAs for Metabolic Disorders
#1849Methods for treatment of polycystic kidney disease
#1850Compositions and methods of use of CRISPR-Cas systems in nucleotide repeat disorders
#1851Tetragalnac and peptide containing conjugates and methods for delivery of oligonucleotides
#1852RNA containing composition for treatment of tumor diseases
#1853COMBINATIONS THERAPIES FOR THE TREATMENT OF CANCER
#1854Administration of polynucleotide toll-like receptor 9 agonists for treating cancer
#1855Agent for inducing cell death, agent for suppressing cell proliferation, and pharmaceutical composition used for treatment of disease resulting from abnormal cell proliferation
#1856RNAi-MEDIATED INHIBITION OF HIF1A FOR TREATMENT OF OCULAR ANGIOGENESIS
#1857RNAi induced huntingtin gene suppression
#1858Methods and compositions for the specific inhibition of transthyretin (TTR) by double-stranded RNA
#1859T cell differentiation and function regulation by decreasing let7 expression
#1860Compositions and methods for selective inhibition of grainyhead-like protein expression
#1861Functionalized Nanoparticles and Compositions for Cancer Treatment and Methods
#1862Methods for promoting entry of an agent into a cell
#1863Liposomes comprising polymer-conjugated lipids and related uses
#1864Method for preventing or treating obesity by using a composition including HOGA1-inhibiting substance and method of screening a preventive or therapeutic agent for obesity by using the composition
#1865Compositions and methods for manipulation of adipocyte energy consumption regulatory pathway
#1866Cell based anti-cancer compositions with reduced toxicity and methods of making the same
#1867GLP-1 Receptor Ligand Moiety Conjugated Oligonucleotides and Uses Thereof
#1868METHODS OF DOWNREGULATING TRANSLOCATED ONCOGENE EXPRESSION USING BROMODOMAIN INHIBITORS
#1869PROCESS FOR THE IDENTIFICATION OF COMPOUNDS FOR TREATING CANCER
#1870Compositions for detecting mutant anaplastic lymphoma kinase in lung cancer
#1871MIR-29 MIMICS AND USES THEREOF
#1872Nucleic acid and other compositions and methods for the modulation of cell membranes
#1873Ionizable compounds and compositions and uses thereof
#1874Stabilization of biomolecules using sugar polymers
#1875COMPOUNDS AND METHODS FOR TRANS-MEMBRANE DELIVERY OF MOLECULES
#1876Co-activation of mTOR and STAT3 pathways to promote neuronal survival and regeneration
#1877Compositions and methods for immune cell modulation in adoptive immunotherapies
#1878Compositions and methods for inhibiting expression of TMPRSS6 gene
#1879Methods for improving cognitive function via modulation of quinone reductase 2
#1880MicroRNA-143 derivative
#1881METHODS FOR ENGINEERING NON-NEURONAL CELLS INTO NEURONS AND USING NEWLY ENGINEERED NEURONS TO TREAT NEURODEGENERATIVE DISEASES
#1882Inhibitors of metastasis
#1883Compositions and methods for delivery of agents
#1884TUMOR ANTIGEN PEPTIDE
#1885PROCESS FOR THE IDENTIFICATION OF COMPOUNDS FOR TREATING CANCER
#1886Methods for treating renal disease
#1887Targeting AMP deaminase 2 for ameliorating craving for sugar and other substances
#1888COMPOSITIONS AND METHODS FOR PROGNOSIS OF OVARIAN CANCER
#1889Endomucin inhibitor as an anti-angiogenic agent
#1890Complex containing oligonucleotide having immunopotentiating activity and use thereof
#1891Methods and compositions for managing vascular conditions using miR-483 mimics and HIF1alpha pathway inhibitors
#1892NOVEL CANCER ANTIGEN EEF2
#1893Metabolically stabilized double stranded mRNA
#1894GNAQ targeted dsRNA compositions and methods for inhibiting expression
#1895NOVEL CYCLIC CATIONIC LIPIDS AND METHODS OF USE
#1896Compositions and Methods for Treating Alzheimer's Disease and Other Tauopathies
#1897Conserved HBV and HCV sequences useful for gene silencing
#1898Targeting Lipids
#1899COMPOSITION FOR PROMOTING INTERFERON LAMBDA PRODUCTION AND PRODUCTION METHOD THEREFOR
#1900Medicament for liver regeneration and for treatment of liver failure
#1901Methods of using miRNAs from bodily fluids for detection and differentiation of neurodegenerative diseases
#1902Amphipathic peptide
#1903MEDICAMENT FOR LIVER REGENERATION AND FOR TREATMENT OF LIVER FAILURE
#1904Treatment of cancer by systemic administration of Dbait molecules
#1905Therapies for cardiomyopathy
#1906TARGETING PARP1 FOR TREATMENT OF TSC AND CANCERS
#1907Therapeutic nanoparticles comprising a therapeutic agent and methods of making and using same
#1908Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells
#1909Composition for regulating cell division comprising FCHO1 modulator, and method for regulating cell division using same
#1910Amine cationic lipids and uses thereof
#1911TKI permeability enhancers
#1912Composition comprising PIC for treatment of cancer
#1913BIOSYNTHETIC MODULES
#1914Efficacy of anti-HLA-DR antibody drug conjugate IMMU-140 (hL243-CL2A-SN-38) in HLA-DR positive cancers
#1915Synergistic effect of anti-trop-2 antibody-drug conjugate in combination therapy for triple-negative breast cancer when used with microtubule inhibitors or PARP inhibitors
#1916DEVICES AND METHODS FOR TREATMENT OF OCULAR DISORDERS THROUGH DELIVERY OF THERAPEUTIC NUCLEIC ACIDS
#1917DETECTION OF RECOMBINASE POLYMERASE AMPLIFICATION USING DUAL-HAPTEN PROBE
#1918Antisense antibacterial compounds and methods
#1919Preventing tumor development and metastasis
#1920Methods of modulating KEAP1
#1921Materials and methods for increasing immune responses
#1922CYTIDINE DEAMINASE INHIBITORS FOR THE TREATMENT OF PANCREATIC CANCER
#1923Enhancing plasmin activity to prevent soft tissue calcification
#1924Nanoparticle to target cancer
#1925ANTI-TUMOR THERAPY
#1926Modulation of DYRK1B expression
#1927RNAi-MEDIATED INHIBITION OF HIF1A FOR TREATMENT OF OCULAR ANGIOGENESIS
#1928INHIBITORS OF DEK PROTEIN AND RELATED METHODS
#1929Methods Of Treatment For Alpha-1 Antitrypsin Deficiency
#1930Antibody-drug conjugates and uses thereof
#1931Cancer examination method and examination kit
#1932Tumor cell malignant transformation suppressor and anti-tumor agent
#1933Polyconjugates for Delivery of RNAi triggers to Tumor Cells In Vivo
#1934MicroRNA composition for the treatment of neuroblastoma
#1935Nucleic acid-polypeptide compositions and uses thereof
#1936Nucleic acid-polypeptide compositions and uses thereof
#1937Systemic delivery of myostatin short interfering nucleic acids (siNA) conjugated to a lipophilic moiety
#1938Microbubble complexes and methods of use
#1939Prevention, diagnosis and treatment of cancer overexpressing GPR160
#1940POLYMERASE Q AS A TARGET IN HR-DEFICIENT CANCERS
#1941Methods and compositions using RNA interference for inhibition of KRAS
#1942Nucleic acid conjugate
#1943Compositions and Methods For Treating Cachexia
#1944Targeting pleiotrophin signaling to limit high-grade glioma invasion
#1945COMPOSITIONS AND METHODS FOR MODULATING HBV EXPRESSION
#1946RNA containing composition for treatment of tumor diseases
#1947Cell membrane-permeating peptide
#1948Treatment methods using adenovirus
#1949TALEN-based gene correction
#1950MODULATORS OF CCR9 FOR TREATING TUMOR RESISTANCE TO IMMUNE RESPONSES
#1951Compositions and methods for inhibiting expression of CD274/PD-L1 gene
#1952COMPOSITIONS AND METHODS FOR DELIVERING MICRORNA
#1953CHEMICAL MODIFICATIONS OF MONOMERS AND OLIGONUCLEOTIDES WITH CYCLOADDITION
#1954CROSS-REGULATION OF TYPE I INTERFERON SIGNALING PATHWAYS
#1955Reduced size self-delivering nucleic acid compounds targeting long non-coding RNA
#1956Biodegradable cationic polymers and uses thereof
#1957Pharmaceutical composition for treating and/or preventing cancer
#1958METHODS OF DIAGNOSING AND TREATING B CELL ACUTE LYMPHOBLASTIC LEUKEMIA
#1959Cas discrimination using tuned guide RNA
#1960HIPPO AND DYSTROPHIN COMPLEX SIGNALING IN CARDIOMYOCYTE RENEWAL
#1961BIOLOGICAL MATERIALS AND USES THEREOF
#1962PHARMACEUTICAL COMPOSITIONS AND RELATED METHODS OF DELIVERY
#1963High density lipoprotein binding protein (Hdlbp/Vigilin) iRNA compositions and methods of use thereof
#1964Compositions and methods for treating fibrotic disease
#1965MEANS FOR LUNG SPECIFIC DELIVERY
#1966RNA complexes that inhibit melanin production
#1967SYSTEMIC SYNTHESIS AND REGULATION OF L-DOPA
#1968RNAi-Mediated Inhibition of Tumor Necrosis Factor Alpha-Related Conditions
#1969NON-LIPOSOMAL SYSTEMS FOR NUCLEIC ACID DELIVERY
#1970Methods and pharmaceutical compositions for enhancing CD8+ T cell-dependent immune responses in subjects suffering from cancer
#1971Antibody-SN-38 immunoconjugates with a CL2A linker
#1972BREAST CANCER THERAPEUTICS
#1973Method for monitoring cancer and for regulation of semaphorin 4D to improve cancer immunotherapy regimens
#1974Interfering RNA molecules
#1975Treatment of filaggrin (FLG) related diseases by modulation of FLG expression and activity
#1976EDITING MITOCHONDRIAL DNA
#1977THERAPEUTIC DRUG FOR MALIGNANT TUMORS
#1978ANTI-IL-6 ANTIBODIES FOR THE TREATMENT OF ORAL MUCOSITIS
#1979Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
#1980Antiviral drugs
#1981Reagents for treatment of hepatitis B virus (HBV) infection and use thereof
#1982RNAi therapy for hepatitis B virus infection
#1983MYO1A for predicting conversion of acute pain into chronic pain and use of MYO1A for therapy of pain
#1984Oligonucleotide compositions with enhanced efficiency
#1985Dual molecular delivery of oligonucleotides and peptide containing conjugates
#1986Compositions and methods for treating malignant, autoimmune and inflammatory diseases
#1987Methods for treating brain metastases using combinations of anti-P13K and anti-mTOR agents
#1988Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
#1989SYNTHETIC LETHALITY AND THE TREATMENT OF CANCER
#1990COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF MUTANT EGFR GENE
#1991PREVENTIVE OR THERAPEUTIC AGENT FOR FIBROSIS
#1992Monocarboxylate transporter 4 (MCT) antisense oligonucleotide (ASO) inhibitors for use as therapeutics in the treatment of cancer
#1993Treatment of autophagy-based disorders and related pharmaceutical compositions, diagnostic and screening assays and kits
#1994Methods of detecting and reducing cancer cell central nervous system colonization
#1995Methods of treating cancer by inhibition of DNA repair proteins using antisense based therapies
#1996DOUBLE-STRANDED OLIGONUCLEOTIDES
#1997Methods and pharmaceutical compositions for the treatment of diseases mediated by the NRP-1/OBR complex signaling pathway
#1998Peptides and nanoparticles for intracellular delivery of molecules
#1999Lipids and lipid compositions for the delivery of active agents
#2000Carrier nanoparticles and related compositions, methods and systems
#2001Nucleic acid-polypeptide compositions and uses thereof
#2002Nucleic acid-polypeptide compositions and methods of inducing exon skipping
#2003Synthetic lethality and the treatment of cancer
#2004Compositions and methods for controlling arthropod parasite and pest infestations
#2005Formulation comprising extracellular vesicles, method for producing the same, and uses thereof
#2006Nucleic acid-polypeptide compositions and uses thereof
#2007Nucleic acid-polypeptide compositions and methods of inducing exon skipping
#2008Targeted sensitization of non-del(5q) malignant cells
#2009Lipids and lipid compositions for the delivery of active agents
#2010COMPOSITIONS FOR NUCLEIC ACID DELIVERY
#2011MRNA combination therapy for the treatment of cancer
#2012METHOD FOR TREATING OR PREVENTING OSTEOARTHRITIS
#2013Antisense oligomers for treatment of autosomal dominant mental retardation-5 and Dravet Syndrome
#2014METHODS OF DELIVERING OLIGONUCLEOTIDES TO IMMUNE CELLS
#2015NANOVECTORS FOR PENETRATING BRAIN TUMOR TISSUES TO CONDUCT GENE THERAPY
#2016UNA oligomers having reduced off-target effects in gene silencing
#2017Methods and compositions for managing vascular conditions
#2018Methods and compositions for reprogramming cells
#2019Pharmaceutical composition for treating and/or preventing cancer
#2020RNA interference mediated inhibition of gene expression using short interfering nucleic acids (siNA)
#2021ESOPHAGEAL CANCER MARKER AND USE THEREOF
#2022REGULATION OF CYTOKINE PRODUCTION
#2023MicroRNA (miRNA) and downstream targets for diagnostic and therapeutic purposes
#2024ANTI-INFLUENZA VIRUS AGENT AND SCREENING METHOD FOR ANTI-INFLUENZA VIRUS AGENT
#2025Treatment of tinnitus through modulation of chloride co-transporter NKCC1 in the auditory system
#2026Organic compositions to treat beta-ENaC-related diseases
#2027Peptide, Complex of Peptide and siRNA, and Methods of Use Thereof
#2028SYSTEMS AND METHODS OF DELIVERY OF BIOACTIVE AGENTS USING BACTERIAL TOXIN-DERIVED TRANSPORT SEQUENCES
#2029POLYINOSINIC-POLYCYTIDYLIC ACID (POLY (I:C)) PEA STARCH FORMULATION FOR THE PREVENTION AND/OR TREATMENT OF UPPER RESPIRATORY TRACT INFECTIONS
#2030Double-stranded nucleic acid molecule, DNA, vector, cancer cell growth inhibitor, cancer cell migration inhibitor, and drug
#2031Nucleic acid-containing lipid nanoparticles
#2032DNA aptamer binding to cancer cell
#2033Methods and compositions for reprogramming cells
#2034MICRORNA-198 AS A TUMOR SUPPRESSOR IN OVARIAN CANCER
#2035Serpina1 iRNA compositions and methods of use thereof
#2036Methods of reducing expression of X-inactivation escapee genes and autosomal genes
#2037Cysteine Peptide-Containing Health Drink
#2038Use of antisense oligonucleotides for producing truncated Ig by exon skipping for the treatment of diseases involving B cells
#2039METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF HEPATOCELLULAR CARCINOMAS
#2040Donor organ pre-treatment formulation
#2041Antitumor drug delivery formulation
#2042Means and methods for reducing tumorigenicity of cancer stem cells
#2043siRNA compositions that specifically downregulate expression of a variant of the PNPLA3 gene and methods of use thereof for treating a chronic liver disease or alcoholic liver disease (ALD)
#2044Combination therapy with anti-HLA-DR antibodies and kinase inhibitors in hematopoietic cancers
#2045CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES
#2046MODULATION OF AXON DEGENERATION
#2047Composition for ameliorating loss of hair and graying of hair, and use thereof
#2048Polyinosinic-polycytidylic acid (poly (I:C)) formulations for the treatment of upper respiratory tract infections
#2049METHOD OF EVALUATING OR SELECTING ANDROGEN RECEPTOR ACTIVITY REGULATOR SELECTIVE TO SEBACEOUS GLANDS OR HAIR FOLLICLES
#2050Immunoregulatory agent
#2051Methods and pharmaceutical compostions for treating rhabdomyolysis
#2052BIOCOMPATIBLE WATER-SOLUBLE POLYMERS INCLUDING SULFOXIDE FUNCTIONALITY
#2053Toxic RNAi active seed sequences for killing cancer cells
#2054Methods and Compositions for Selecting siRNA of Improved Functionality
#2055Agents and methods for treating and preventing seborrheic keratosis
#2056Method for determining presence or absence of suffering from malignant lymphoma or leukemia, and agent for treatment and/or prevention of leukemia
#2057Complex comprising RNAi molecule and N-acetylated chitosan
#2058Nanostructured gels capable of controlled release of encapsulated agents
#2059Targeting CAPN9/CAPNS2 activity as a therapeutic strategy for the treatment of myofibroblast differentiation and associated pathologies
#2060NMDAR antagonists for the treatment of diseases associated with angiogenesis
#2061Method for treating schizophrenia
#2062Method of treating obesity
#2063COMPOSITIONS AND METHODS FOR TREATING CYSTIC FIBROSIS
#2064Methods and compositions related to T-cell activity
#2065Identification and use of target genes for control of plant parasitic nematodes
#2066COMPOUNDS AND METHODS FOR MODULATING APOLIPOPROTEIN C-III EXPRESSION FOR IMPROVING A DIABETIC PROFILE
#2067System comprising a nucleotide sequence encoding a volvox carteri light-activated ion channel protein (VCHR1)
#2068Methods and compositions relating to proteasome inhibitor resistance
#2069METHODS AND COMPOSITIONS FOR PREVENTING ISCHEMIA REPERFUSION INJURY IN ORGANS
#2070Treatment of down syndrome gene related diseases by inhibition of natural antisense transcript to a down syndrome gene
#2071Targeting MicroRNAs for the Treatment of Fibrosis
#2072POLYNUCLEOTIDES HAVING BIOREVERSIBLE GROUPS
#2073Pharmaceutical Composition for Treating STK11-Mutation Cancer Using Cardiac Glycosides
#2074Hair-growth promoting composition and usage thereof
#2075Peptide oligonucleotide conjugates
#2076Modified AAV constructs and uses thereof
#2077Inhibition of cytokine-induced SH2 protein in NK cells
#2078Compounds for targeting drug delivery and enhancing siRNA activity
#2079TARGETED THERAPEUTIC NUCLEOSIDES AND THEIR USE
#2080Compositions for treating heart disease by inhibiting the action of mAKAP-β
#2081Rapid identification of microorganisms
#2082Interfering RNA molecules
#2083Blood Brain Barrier Opening Agents and Uses Thereof
#2084Lipids and lipid compositions for the delivery of active agents
#2085Micelle composition for nucleic acid delivery using temperature-sensitive polymer and method for producing same
#2086Therapeutic agent for sarcopenia and metabolic diseases
#2087Lin28/let-7 crystal structures, purification protocols, and molecular probes suitable for screening assays and therapeutics
#2088ORGANIC COMPOSITIONS TO TREAT BETA-CATENIN-RELATED DISEASES
#2089Lipid formulated compositions and methods for inhibiting expression of Serum Amyloid A gene
#2090Plasma cell cytokine vehicle containing fusion proteins for targeted introduction of siRNA into cells and tissues
#2091METHODS AND COMPOSITIONS FOR PREVENTING A CONDITION
#2092METHODS TO TARGET TRANSCRIPTIONAL CONTROL AT SUPER-ENHANCER REGIONS
#2093Methods for treating Angelman syndrome and related disorders
#2094Histone deacetylase inhibitors for the use in the treatment of drug resistant melanoma
#2095Sterol regulatory element binding protein (SREBP) chaperone (SCAP) iRNA compositions and methods of use thereof
#2096Compositions and methods for modulating apolipoprotein (a) expression
#2097Compositions and methods for modulating apolipoprotein C-III expression
#2098Methods and compositions for the production of siRNAs
#2099Programmed cell death 1 ligand 1 (PD-L1) iRNA compositions and methods of use thereof
#2100LIN28- MEDIATED CONTROL OF LET-7 BIOGENESIS