97307 ⎘
Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Methods of treating progressive forms of multiple sclerosis comprising subcutaneously administering daclizumab
#10502Multivalent fibronectin based scaffold domain proteins
#10503Nucleic acids that encode interleukin-6 receptor binding polypeptides
#10504Anti-c-Met antibodies
#10505IL-17 binding proteins
#10506Methods of treating autoimmune diseases by administering monoclonal antibodies against human IL-12
#10507Neutralising antibodies to the major exotoxins TCDA and TCDB of
#10508Anti-GITR antibodies
#10509Modified polypeptides for bispecific antibody scaffolds
#10510Binding molecules for BCMA and CD3
#10511Anti-CD40 antibodies and methods of treating cancer
#10512Anti-DLL4/VEGF dual variable domain immunoglobulin and uses thereof
#10513Methods and antibodies for treating cancer
#10514Methods for blocking or reducing binding of interleukin-6 to interleukin-6 receptor
#10515Methods and compositions to treat and detect misfolded-SOD1 mediated diseases
#10516Immunoglobulins with reduced aggregation
#10517IL-17 binding proteins
#10518Anti-human CTGF antibody
#10519Anti IL-6R polypeptides and compositions thereof
#10520Nucleic acids encoding antibodies to CCR2
#10521Anti-PD-L1 antibodies and uses thereof
#10522Bispecific antibody fragments for neurological disease proteins and methods of use
#10523Biological materials related to c-Met
#10524Anti-folate receptor alpha antibodies and uses thereof
#10525Humanized anti-human NKG2A monoclonal antibody
#10526Antibodies against human CSF-1R and uses thereof
#10527Nucleic acid assembly, vector, cell, methods and kit thereof
#10528Immunogens comprising human immunodeficiency virus V1/V2 polypeptides
#10529IN SILICO AFFINITY MATURATION
#10530Method of isolating human antibodies
#10531Anti-glucagon antibodies and uses thereof
#10532PD-1 antibodies and PD-L1 antibodies and uses thereof
#10533Anti-glucagon receptor antibodies and pharmaceutical compositions thereof
#10534Antibodies and vaccines for use in therapeutic and diagnostic methods for α-synuclein-related disorders
#10535Methods of inhibiting plasma kallikrein in edema patient
#10536Histidine engineered light chain antibodies and genetically modified non-human animals for generating the same
#10537Nucleic acids encoding IL-6R-binding polypeptides
#10538Human immunodeficiency virus neutralizing antibodies and methods of use thereof
#10539Apelin antigen-binding proteins and uses thereof
#10540Anti-properdin antibodies
#10541Affinity peptides toward infliximab
#10542Anti-integrin β1 antibody compositions and methods of use thereof
#10543Adrenomedullin assays and methods for determining mature adrenomedullin
#10544Nucleic acids encoding antibodies that bind colony stimulating factor 1 receptor (CSF1R)
#10545Dual specific immunotoxin for brain tumor therapy
#10546Anti-IL-6 receptor antibodies and methods of use
#10547Methods of modulating adrenomedullin by administering an anti-adrenomedullin (ADM) antibody
#10548Antibodies useful in passive influenza immunization
#10549Broadly neutralizing HIV-1 VRC07 antibodies that bind to the CD4-binding site of the envelope protein
#10550Methods and agents for the diagnosis and treatment of hepatocellular carcinoma
#10551Anti-B7-H4 antibodies and immunoconjugates
#10552Nucleic acids encoding interleukin-31 monoclonal antibody and uses thereof
#10553Anti-C5A binding moieties with high blocking activity
#10554Method of treating cancer by administering CSF-1R antibodies and a TLR9 agonist
#10555Antibodies binding to IL-17A
#10556Polypeptides that bind to IL-17A, IL-17F and/or IL17-A/F and method of treatment using same
#10557Endoglin antibodies
#10558BMP-6 antibodies and DNA encoding the same
#10559Sur-binding proteins against ERBB3
#10560Method of treating cancer using anti-c-Met antibody and FGFR inhibitor combination therapy
#10561Antibodies directed against the alpha chain of IL7 receptor—their use for the preparation of drug candidates
#10562Anti-ErbB3 antibodies and uses thereof
#10563Class I anti-CEA antibodies and uses thereof
#10564Antibodies that bind to TL1A and their uses
#10565Targeted self-assembly of functionalized carbon nanotubes on tumors
#10566Liquid formulation containing a protein drug
#10567Anti-CD47 antibodies and methods of use thereof
#10568Human antibodies specifically binding to the hepatitis B virus surface antigen
#10569Anti-idiotype antibody against anti-c-MET antibody
#10570Influenza virus antibody compositions
#10571Methods of treating cancer by administering anti-GPR49 antibodies
#10572Anti-GPR49 monoclonal antibodies
#10573Method of treating hereditary angioedema using plasma kallikrein binding antibodies
#10574Thrombin-binding antibody molecules
#10575Anti-Axl antibodies and uses thereof
#10576Combination therapy using anti-C-met antibody and anti-ang-2 antibody
#10577ANTI-C-MET tandem Fc bispecific antibodies
#10578Albumin binding antibodies and binding fragments thereof
#10579Method of treating solid cancers using anti-c-Met antibody and sorafenib combination therapy
#10580Anti-clusterin antibodies and antigen binding fragments and their use to reduce tumor volume
#10581Binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind CD154 and uses thereof
#10582Antibodies against human IL33R and uses thereof
#10583Antibody drug conjugates
#10584Human anti-SOD1 antibodies
#10585HLA-restricted, peptide-specific antigen binding proteins
#10586Antibacterial polymers and method for obtaining the same
#10587Site-specific antibody-drug conjugation through glycoengineering
#10588Antagonistic DR3 ligands
#10589Biological materials related to c-Met
#10590Bispecific anti-Cmet/anti-Her2 antibodies
#10591Fusion protein comprising anti-c-Met antibody and VEGF-binding fragment
#10592Methods of treating a tauopathy
#10593Fully human antibodies that bind to VEGFR2 and methods of use thereof
#10594Humanized and affinity-matured anti-c-Met antibody and uses thereof
#10595FC VARIANTS THAT IMPROVE FCRN BINDING AND/OR INCREASE ANTIBODY HALF-LIFE
#10596Human monoclonal antibody neutralizing vascular endothelial growth factor receptor and use thereof
#10597Antibody and antibody mimetic for visualization and ablation of endogenous proteins
#10598MET-binding agents and uses thereof
#10599Antigen binding proteins
#10600Animal models and therapeutic molecules
#10601Anti-TFPI antibody variants with differential binding across PH range for improved pharmacokinetics
#10602Human monoclonal antibodies and methods for producing the same
#10603Anti-human IL-23 receptor antibody
#10604Human monoclonal antibody neutralizing vascular endothelial growth factor receptor and use thereof
#10605Human antibodies that bind human TNF-alpha and methods of preparing the same
#10606Methods, compositions, and kits for detection of aspergillosis
#10607HCV core lipid binding domain monoclonal antibodies
#10608Antibody drug conjugates
#10609Therapeutic uses for VEGFR1 antibodies
#10610Therapeutic use of antibodies to HGF
#10611Anti-IL-33 antibodies
#10612Neutralizing anti-influenza A virus antibodies and uses thereof
#10613Human antibodies to respiratory syncytial virus F protein and methods of use thereof
#10614Anti-GP73 monoclonal antibodies and methods of obtaining the same
#10615Interferon alpha and omega antibody antagonists
#10616Pan-ELR+ CXC Chemokine Antibodies
#10617Monospecific and bispecific human monoclonal antibodies targeting insulin-like growth factor II (IGF-II)
#10618Humanized, anti-N2 antibodies
#10619Humanized anti-N2 antibodies and methods of treating ischemia-reperfusion injury
#10620Anti-notch NRR antibodies and methods using same
#10621Antibodies to carcinoembryonic antigen-related cell adhesion molecule (CEACAM)
#10622Ion concentration-dependent binding molecule library
#10623Antibodies that bind integrin alpha-V beta-8
#10624Therapeutic use of antibodies to HGF
#10625Antibodies to HGF and compositions containing
#10626Dual specific binding proteins directed against IL-1 and/or IL-17
#10627Immuno imaging agent for use with antibody-drug conjugate therapy
#10628Velocity factor
#10629Methods of blocking cancer stem cell growth
#10630Method of treating stress hyperglycemia with human antibodies to the glucagon receptor
#10631Diagnostic antibody assay
#10632Methods for the treatment of IL-1β related diseases
#10633Method of treating rheumatoid arthritis with an anti-IL-6R antibody
#10634Immuno imaging agent for use with antibody-drug conjugate therapy
#10635TDP-43 specific binding molecules
#10636Anti-VCAM-1 nanobodies
#10637Epitopes
#10638Human immunodeficiency virus type 1 (HIV-1) N-terminal deleted GP120 immunogens
#10639Glycan-modified anti-CD4 antibody with improved HIV-1 neutralizing activity
#10640Fusions of antibodies to CD38 and attenuated interferon alpha
#10641High-throughput system and method for identifying antibodies having specific antigen binding activities
#10642Bispecific T cell activating antigen binding molecules
#10643Antibody variants and uses thereof
#10644M-CSF specific monoclonal antibody and uses thereof
#10645Frizzled 2 as a target for therapeutic antibodies in the treatment of cancer
#10646Alpha-synuclein antibodies and uses thereof
#10647Antibodies to CD70
#10648Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (PCSK9)
#10649Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (PCSK9)
#10650Peptide or arrangement of peptides forming a epitope binding site
#10651HUMAN CTLA-4 ANTIBODIES AND THEIR USES
#10652Antibodies against the ectodomain of ERBB3 and uses thereof
#10653Human tissue factor antibody and uses thereof
#10654Modified variable domain molecules and methods for producing them
#10655Methods of treating a tauopathy
#10656Chimeric and humanized anti-histone antibodies
#10657Dual variable domain immunoglobulins and uses thereof
#10658Serum albumin binding proteins
#10659Prolactin receptor binding proteins and uses thereof
#10660Anti-MCAM antibodies and associated methods of use
#10661Method of treating pain with anti-human NGF antibody
#10662Anti-pseudomonas Psl binding molecules and uses thereof
#10663Anti-Axl antibodies and uses thereof
#10664Combination therapy of anti-HER3 antibodies
#10665Antibody-SN-38 immunoconjugates with a CL2A linker
#10666Humanized anti-HLA-DR antibodies
#10667Humanization of rabbit antibodies using a universal antibody framework
#10668Interleukin-6 receptor binding polypeptides
#10669Monovalent binding proteins
#10670Anti-CD154 antibodies
#10671Therapeutic use of specific ligand in MSRV associated diseases
#10672IL-1 binding proteins
#10673IL-11R binding proteins
#10674Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
#10675ADAM6 mice
#10676IL-1 binding proteins
#10677Rapid clearance of antigen complexes using novel antibodies
#10678Antibodies specific for urokinase-type plasminogen activator and methods of treating cancer
#10679Antibodies to IL-1 R1 and methods of making them
#10680Human IL-23 antigen binding proteins
#10681Anti-properdin antibodies and uses thereof
#10682Toll-like receptor 3 antagonists
#10683Anti-TNF-alpha antibodies and their uses
#10684Anti-CEA antibodies
#10685IL-1 binding proteins
#10686Nucleic acid molecule encoding target antibodies directed to DLL4
#10687Broadly neutralizing human immunodeficiency virus type 1 (HIV-1) GP120-specific monoclonal antibody
#10688Anti-FOLR1 antibody
#10689Anti c-Met antibodies
#10690Optimized antibodies that target HM1.24
#10691Antigen binding constructs
#10692Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains
#10693IL-1 binding proteins
#10694Inhibitory anti-factor XII/XIIA monoclonal antibodies and their uses
#10695Compositions and methods for antibodies targeting EPO
#10696TECHNIQUES FOR PREDICTING, DETECTING AND REDUCING ASPECIFIC PROTEIN INTERFERENCE IN ASSAYS INVOLVING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS
#10697Heterodimerized polypeptide
#10698Antibody drug conjugates (ADC) that bind to 161P2F10B proteins
#10699Dual specificity antibody fusions
#10700Monoclonal antibodies to fibroblast growth factor receptor 2
#10701Anti-c-Met antibody having HGF activity and use thereof
#10702Anti-GDF15 antibodies
#10703Anti-human EPO receptor antibodies and methods of use
#10704Bispecific anti-EGFR/anti IGF-1R antibodies
#10705Antibodies binding to phosphorylcholine (PC) and/or PC conjugates
#10706Antibodies specific to IL-17A and IL-17F
#10707Anti-PDGFR-beta antibodies and uses thereof
#10708Stable and soluble antibodies inhibiting TNF alpha
#10709Nucleic acids encoding a human monoclonal antibody that specifically binds to IL-1α
#10710Monoclonal antibodies against Glypican-3
#10711Polynucleotides encoding IL-31 monoclonal antibodies
#10712Anti-interferon gamma antibodies and methods of use thereof
#10713HER3 antibodies binding to the beta-hairpin of HER3
#10714Anti-granulysin antibodies and methods of use thereof
#10715Polynucleotides encoding anti-CD40 antibodies
#10716Methods and compositions for targeting polyubiquitin
#10717Inhibitors of type 2 vascular endothelial growth factor receptors
#10718Methods for the generation of multispecific and multivalent antibodies
#10719Nucleic acid encoding hepatocyte growth factor (HGF) binding proteins
#10720Antibodies against phosphorylcholine
#10721Anti-IL-23 antibodies
#10722Amino acid sequence presenting fusion polypeptide and its use
#10723IL-1 binding proteins
#10724Isolated DNA sequences encoding, and methods for making, antibody molecules having binding specificity for human IL-13
#10725Generation of anti-FN14 monoclonal antibodies by ex-vivo accelerated antibody evolution
#10726Antibody-like proteins for therapeutic and diagnostic use
#10727Method for treating psoriasis by administering an anti-IL-12 antibody
#10728Methods of generating libraries and uses thereof
#10729Inhibition of bone resorption with RANKL binding peptides
#10730Compositions and methods of use for antibodies of Dickkopf-1
#10731Antibody recognizing N-domain of midkine
#10732Compositions and methods for the treatment of neuromyelitis optica
#10733Compositions and methods related to antibodies to staphylococcal protein A
#10734Glypican-3-specific antibody and uses thereof
#10735Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
#10736Antibody specific for CD22 and methods of use thereof
#10737BCMA antigen binding proteins
#10738Bispecific antibodies directed against TNF-α and IL-17
#10739Conjugated anti-CD38 antibodies
#10740Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen
#10741EGFR and C-Met fibronectin type III domain binding molecules
#10742EGFR and c-Met fibronectin type III domain binding molecules
#10743Heterodimeric immunoglobulins
#10744Animal models and therapeutic molecules
#10745EPHB3-specific antibody and uses thereof
#10746HA binding agents
#10747Antibodies to CD70
#10748Polypeptides, antibody variable domains and antagonists
#10749Method of treating type 1 diabetes with antagonist IL-7 receptor antibodies
#10750Antibodies to CD70
#10751Antibodies that inhibit metalloproteins
#10752Human monoclonal antibodies to epidermal growth factor receptor (EGFR)
#10753Neutralizing prolactin receptor antibody Mat3 and its therapeutic use
#10754Antibodies against kidney associated antigen 1 and antigen binding fragments thereof
#10755Anti-complement C1s antibodies
#10756Humanized L243 antibodies
#10757Recombinant cell surface capture proteins
#10758Human monoclonal antibodies to O8E
#10759Platelet-derived growth factor B specific antibodies and compositions and uses thereof
#10760Anti-DLL4/VEGF dual variable domain immunoglobulin and uses thereof
#10761Antibodies against prostate-specific stem cell antigen and use thereof
#10762Antibodies for treatment of cancer
#10763Anti-Notch3 antibodies and antibody-drug conjugates
#10764Methods of inhibiting activation of complement component C4 with anti-C1s antibodies
#10765Antibodies against epidermal growth factor receptor (EGFR) and uses thereof
#10766Anti-CD22 antibodies and immunoconjugates and methods of use
#10767Anti-complement C1s
#10768Antibodies recognizing alpha-synuclein
#10769Activation of human antigen-presenting cells through dendritic cell lectin-like oxidized LDL receptor-1 (LOX-1)
#10770Antibodies against clostridium difficile toxins and uses thereof
#10771Animal models and therapeutic molecules
#10772Antibody specifically binding to insulin-like growth factor-1
#10773Anti CEACAM1 antibodies and methods of using same
#10774Treatment of tumors using specific anti-L1 antibody
#10775Antibodies that are cross-reactive for macrophage migration inhibitory factor (MIF) and D-dopachrome tautomerase (D-DT)
#10776Antibodies to EphA3
#10777Human binding molecules capable of neutralizing influenza A viruses of phylogenetic group 1 and phylogenetic group 2 and influenza B viruses
#10778Method of treating a TL1A-associated disease or disorder with human antibodies to TL1A
#10779Anti-IL12Rbeta1 antibodies and their use in treating autoimmune and inflammatory disorders
#10780Bispecific IgG antibodies as T cell engagers
#10781Antibodies to insulin-like growth factor I receptor
#10782Fc fusion proteins comprising novel linkers or arrangements
#10783Meditopes and meditope-binding antibodies and uses thereof
#10784Antibodies to interleukin-6
#10785Anti-human HER3 antibodies and uses thereof
#10786Methods for treating malaria by administering an antibody that specifically binds angiopoietin-2 (ang-2)
#10787Bispecific monoclonal antibody therapeutics against West Nile virus with improved CNS penetration
#10788Anti-CD19 antibodies
#10789Protein for affinity-separation matrix
#10790Variant target binding agents and uses thereof
#10791Frizzled-binding agents and uses thereof
#10792Human C-FMS antibodies
#10793Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins
#10794Compositions relating to anti-IL-21 receptor antibodies
#10795Anti-IL13 antibodies and uses thereof
#10796Humanized anti-IL-18 antibodies
#10797PTK7 modulators and methods of use
#10798Anti-IL12Rβ1 antibodies and their use in treating autoimmune and inflammatory disorders
#10799Nucleic acids encoding antibody polypeptides that antagonize CD40L
#10800IL-1 binding proteins