97307 ⎘
Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Human oncostatin M antibodies
#10802Interleukin-13 binding proteins
#10803Methods for treating hypercholesterolemia and reducing LDL-C using antibodies to PCSK9
#10804Anti-IL-6 antibodies, compositions, methods and uses
#10805EGFR-binding molecules and immunoconjugates thereof
#10806Anti-CD79B antibodies and immunoconjugates and methods of use
#10807Methods of generating libraries and uses thereof
#10808Therapeutic DLL4 binding proteins
#10809Optimization of antibodies that bind lymphocyte activation gene-3 (LAG-3), and uses thereof
#10810Method of treating an inflammatory condition by administering toll-like 3 receptor antagonists
#10811Anti-ricin antibodies and uses thereof
#10812RSV specific binding molecule
#10813Modulators and methods of use
#10814Anti-CD3 antibodies, bispecific antigen-binding molecules that bind CD3 and CD20, and uses thereof
#10815Cytotoxic benzodiazepine derivatives and methods of preparation
#10816Antigenic GM-CSF peptides and antibodies to GM-CSF
#10817Method for treating sarcopenia using antagonist antibodies against GDF-8
#10818Method for preparing Fc containing polypeptides having improved properties
#10819Optimized antibodies that target CD19
#10820Humanized anti-TNF-α antibody and antigen-binding fragment (Fab) thereof and use of the same
#10821Recombinant antibodies to the vascular endothelial growth factor (VEGF) which are obtained by means of mutagenesis of variable regions
#10822Non-human animals expressing pH-sensitive immunoglobulin sequences
#10823Polynucleotides encoding IL-31 monoclonal antibodies
#10824Human monoclonal antibodies against Hendra and Nipah viruses
#10825Method of improving patient survivability and quality of life by anti-IL-6 antibody administration
#10826Anti-tissue factor antibodies and compositions
#10827Antibody drug conjugates (ADC) that bind to 158P1D7 proteins
#10828Anti-CD100 antibodies and methods of using the same
#10829Antibodies that specifically bind alpha toxin and methods of use
#10830Monoclonal antibodies for enhancing or inhibiting insulin-like growth factor 1 (IGF-1)
#10831Methods and compositions comprising a combination of an anti-ErbB3 antibody and an anti-EGFR antibody
#10832High affinity antibodies that neutralize enterotoxin B
#10833Methods of treating sickle cell disease with anti-P-selectin antibodies
#10834Antibodies against human angiopoietin 2
#10835DNA encoding antibody molecules which bind IL-17A and IL-17F
#10836Anti-kit antibodies
#10837Antibody with specificity for GM-CSF (II)
#10838Human binding molecules capable of neutralizing influenza virus H5N1 and uses thereof
#10839Neutralizing monoclonal antibodies against the Nogo-66 receptor (NgR) and uses thereof
#10840Antibodies against human angiopoietin 2
#10841Methods and systems for treating eclampsia or pre-eclampsia
#10842Anti-N3pGlu amyloid beta peptide antibodies and uses thereof
#10843Humanized anti-factor D antibodies and uses thereof
#10844Therapeutic use of anti-CS1 antibodies
#10845Complex in which anti-cotinine antibody is bound to conjugate of cotinine and binding substance, and use thereof
#10846High affinity antibody antagonists of interleukin-13 receptor alpha 1
#10847Human cytomegalovirus neutralising antibodies and use thereof
#10848Anti-dengue virus antibodies and uses thereof
#10849Anti-ASIC1 antibodies and uses thereof
#10850Anti-kit antibodies
#10851Human antibodies to GFRα3 and methods of use thereof
#10852Anti-HER antibodies
#10853Dual variable region antibody-like binding proteins having cross-over binding region orientation
#10854High concentration antibody formulations
#10855Humanized anti-IL-20 antibody and uses thereof
#10856Humanized antibodies directed against complement protein C5
#10857Neoantibodies for diagnosing tissue injury
#10858Aldolases, nucleic acids encoding them and methods for making and using them
#10859Anti-tace antibody molecules and their uses
#10860Antibodies
#10861Antibodies directed against influenza
#10862Antibodies comprising site-specific non-natural amino acid residues, methods of their preparation and methods of their use
#10863Nucleic acids encoding neutralizing anti-CCL20 antibodies
#10864CDIM binding proteins and uses thereof
#10865Anti-PCSK9 antibodies with pH-dependent binding characteristics
#10866Anti-TIM-3 antibody
#10867Anti-SOD1 antibodies and uses thereof
#10868Human monoclonal antibodies that bind insulin-like growth factor (IGF) I and II
#10869VNAR anti-cytokine domains
#10870Human monoclonal antibodies specific for glypican-3 and use thereof
#10871Human monoclonal antibody human CD134 (OX40) and methods of making and using same
#10872Interleukin-10 fusion proteins
#10873Nucleic acids encoding anti-NR10 antibodies
#10874Compositions and methods of use of immunotoxins comprising ranpirnase (Rap) show potent cytotoxic activity
#10875Antibodies that neutralize RSV, MPV and PVM and uses thereof
#10876Antigen binding formats for use in therapeutic treatments or diagnostic assays
#10877Anti-FGFR4 antibodies and methods of use
#10878Expandable liquid volume in an LED bulb
#10879A-beta binding polypeptides
#10880Human antibodies and antibody-drug conjugates against CD74
#10881METHODS OF TREATING OR PREVENTING CHOLESTEROL RELATED DISORDERS
#10882Modified antibody compositions, methods of making and using thereof
#10883Methods for making antibody molecules having specificity for human IL-6
#10884Non-antagonistic EGFR-binding molecules and immunoconjugates thereof
#10885Methods of enhancing antibody-based antiviral therapies by administering KIR2DL-binding antibodies
#10886Antibodies specific for TGF-β and methods of treatment thereof
#10887Antibody with specificity for GM-CSF (I)
#10888Antibody to GDF8 and uses thereof
#10889RSPO3 binding agents and uses thereof
#10890Bispecific anti-VEGF/anti-ANG-2 antibodies and their use in the treatment of ocular vascular diseases
#10891Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same
#10892Material and methods for treating or preventing HER-3 associated diseases
#10893Antibodies against influenza virus and methods of use thereof
#10894Dual variable region antibody-like binding proteins having cross-over binding region orientation
#10895Antibody for 3′-isoLM1 and 3′,6′-iso-LD1 gangliosides
#10896Anti-jagged 1/jagged 2 cross-reactive antibodies, activatable anti-jagged antibodies and methods of use thereof
#10897Anti CD37 antibodies
#10898Anti-IL-18 antibodies and their uses
#10899Pharmaceutical compositions comprising IL-1B binding antibodies and fragments thereof
#10900Anti-DR5 antibodies, polynucleotides and methods
#10901antibodies
#10902Stable and soluble antibodies inhibiting VEGF
#10903Therapeutic peptides
#10904ST2 antigen binding proteins
#10905Nucleic acids encoding human glucagon receptor antibodies
#10906Anti-human TROP-2 antibody having an antitumor activity in vivo
#10907Anti-EGFR antibodies and uses thereof
#10908Anti-PCSK9 antibodies, formulations, dosing, and methods of use
#10909Anti-VEGF-C antibodies and methods using same
#10910Antigen binding proteins that bind CCR2
#10911Monoclonal antibody recognizing human papillomavirus (HPV) L2 protein and method for measuring HPV-neutralizing antibody titer using the same
#10912Internalizing erbB2 antibodies
#10913Antagonistic DR3 ligands
#10914ST2L antibody antagonists
#10915Binding members for interleukin-4 receptor alpha (IL-4Rα) - 173
#10916Anti-TrkA antibodies, derivatives and uses thereof
#10917Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
#10918Anti-LGR5 antibodies and immunoconjugates
#10919Means and methods for producing high affinity antibodies
#10920Anti-ErbB3 antibodies
#10921Compositions relating to a mutant toxin and methods thereof
#10922Humanized anti-EGFR antibody L4-H3 and coding gene thereof
#10923Antagonistic DR3 ligands
#10924Anti-IL-1β antibodies
#10925Anti-NGF antibodies and their use
#10926Chemokine receptor binding polypeptides
#10927Antibody molecules having specificity for human OX40
#10928Composition and method for the diagnosis and treatment of iron-related disorders
#10929Single-domain antibodies that bind to HIV-1 Nef with high affinity
#10930Antibodies for epidermal growth factor receptor 3 (HER3)
#10931Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of tryptophanyl-tRNA synthetases
#10932LOX and LOXL2 inhibitors and uses thereof
#10933Antibodies that bind the glutamate ligand binding region of NOTCH3
#10934Antigen binding proteins that bind PD-L1
#10935Antigen binding proteins that bind delta-like 4 (DLL-4)
#10936Antagonists of IL-6 to raise albumin and/or lower CRIP
#10937Soluble heavy-chain only antibodies
#10938Antibodies to tumor endothelial marker 8
#10939Antibodies and immunoconjugates and uses therefor
#10940Human monoclonal antibodies specific for CD22
#10941Anti-VEGF antibodies
#10942Anti-TLR4 antibodies and uses thereof
#10943Bispecific antibodies to IL-23 and IL-17A/F
#10944Activatable antibodies that bind epidermal growth factor receptor and methods of use thereof
#10945Humanized anti-IL-20 antibody and uses thereof
#10946Use of an anti-Tau pS422 antibody for the treatment of brain diseases
#10947Human binding molecules capable of neutralizing influenza virus H3N2 and uses thereof
#10948Methods of treating vascular disease using an IL-1beta Antibody
#10949Antibodies that bind and block triggering receptor expressed on myeloid cells-1 (TREM-1)
#10950Pathogenic mycobacteria-derived mannose-capped lipoarabinomannan antigen binding proteins
#10951Antagonists of IL-17A, IL-17F, and IL-23P19
#10952Antibodies that bind epidermal growth factor receptor (EGFR)
#10953Affinity peptides toward infliximab
#10954Express humanization of antibodies
#10955Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
#10956Compositions and methods for promoting liposomal and cellular adhesion
#10957Antibodies directed against pyroglutamate monocyte chemoattractant protein-1 (MCP-1 N1pE)
#10958Anti-PCSK9 antibodies and use thereof
#10959Modulators and methods of use
#10960Alpha-4-beta-7 heterodimer specific antagonist antibody
#10961HA binding agents
#10962Agents for influenza neutralization
#10963Single variable domain immunoglobulins that bind TGF-beta receptor II
#10964Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same
#10965Covalently-associated diabody complexes that possess charged coil domains and that are capable of enhanced binding to serum albumin
#10966Anti-C5a receptor antibodies
#10967Anti-erythropoietin antibodies
#10968Antibodies against nerve growth factor (NGF) with enhanced in vivo stability
#10969Monoclonal antibodies against frizzled
#10970CD37-binding molecules and immunoconjugates thereof
#10971Antibodies that bind factor P
#10972Human antibodies to Fel d1 and methods of use thereof
#10973Humanized monoclonal antibodies that specifically bind and/or neutralize Japanese encephalitis virus (JEV) and their use
#10974Binding proteins having tethered light chains
#10975Dock-and-Lock (DNL) Complexes for delivery of interference RNA
#10976Fibronectin based scaffold domain proteins that bind IL-23
#10977Humanized anti-beta7 antagonists and uses therefor
#10978Anti-ephrin-B2 antibody and compositions comprising it
#10979Monoclonal antibodies that react with the capsule of
#10980ST2L antibody antagonists for the treatment of ST2L-mediated inflammatory pulmonary conditions
#10981Anti-FGFR3 antibodies and methods using same
#10982Human anti-KIR antibodies
#10983Cells expressing anti-GD2 antibodies and methods related thereto
#10984Antibodies against ROR1 and uses thereof
#10985Antigen associated with the neovasculature of tumour metastases
#10986Antibody targeting osteoclast-related protein Siglec-15
#10987Antibodies to IL-6 and their uses
#10988Method of treating asthma or reducing inflammatory cell lung inflammation by administering toll-like receptor 3 antibodies
#10989Anti-BAFF-anti-IL-17 bispecific antibodies
#10990Binding proteins specific for insulin-like growth factors and uses thereof
#10991Anti-CD100 neutralizing antibodies and methods of using the same
#10992Peptides for generating an antibody selectively binding to a non-ATP-binding P2X7 receptor but not to an ATP-binding P2X7 receptor
#10993Antibodies to NTB-A
#10994Therapeutic antibodies against ROR-1 protein and methods for use of same
#10995PCSK9 antagonists
#10996Antibodies against a proliferating inducing ligand (APRIL) and methods of use thereof
#10997Preparation of isolated agonist anti-EDAR monoclonal antibodies
#10998FN14 binding proteins and uses thereof
#10999Anti-CEACAM6 antibodies and uses thereof
#11000Idiotypic antibodies and uses thereof
#11001Anti-Notch1 antibodies
#11002Anti-VEGF antibodies
#11003Therapeutic factor VIII antibodies
#11004Human antibodies to human angiopoietin-like protein 4
#11005Antibodies selective for cells presenting ErbB2 at high density
#11006Methods for treating conditions associated with MASP-2 dependent complement activation
#11007Animal models and therapeutic molecules
#11008Animal models and therapeutic molecules
#11009Composition and method for diversification of target sequences
#11010TEM-1 diagnostic antibodies
#11011Anti-HLA-B*27 antibodies and uses thereof
#11012Anti-cobra toxin antibody fragments and method of producing a VH library
#11013Humanized antibodies to LIV-1 and use of same to treat cancer
#11014Polynucleotides encoding for frizzled-binding agents and uses thereof
#11015Anti-CXCR3 antibodies and methods of use thereof
#11016Method of reducing the severity of stress hyperglycemia with human antibodies to the glucagon receptor
#11017Antibodies against tissue factor pathway inhibitor
#11018Humanized anti-CXCR5 antibodies, derivatives thereof and their use
#11019Anti-huTNFR1 antibody and methods of use thereof for treatment
#11020Monoclonal antibodies against Orthopoxviruses
#11021Chimeric rabbit/human ROR1 antibodies
#11022Non-human animals expressing pH-sensitive immunoglobulin sequences
#11023Histidine engineered light chain antibodies and genetically modified non-human animals for generating the same
#11024Humanized anti-CXCR5 antibodies, derivatives thereof and their use
#11025Fibronectin binding domains with reduced immunogenicity
#11026Neutralising antibody molecules having specificity for human IL-17
#11027Human neutrophil gelatinase-associated lipocalin (hNGAL) muteins that bind hepcidin and nucleic acid encoding such
#11028huTNFR1 selective antagonists
#11029Polynucleotides encoding Toll-Like Receptor 3 antagonists
#11030Human anti-CD27 antibodies, methods and uses
#11031Humanized anti-CXCR5 antibodies, derivatives thereof and their use
#11032Notch1 binding agents and methods of use thereof
#11033Antibody molecules having specificity for human OX40
#11034Anti-Axl antibodies and methods of use
#11035Humanized monoclonal antibodies and methods of use
#11036Antibodies
#11037Humanized anti-CXCR5 antibodies, derivatives thereof and their use
#11038Anti IL-36R antibodies
#11039Monospecific and bispecific anti-IGF-1R and anti-ERBB3 antibodies
#11040Dual specific binding proteins directed against IL-13 and IL-17
#11041-specific antibodies and uses thereof
#11042Interferon receptor 1 antibodies and their uses
#11043Methods of treating systemic lupus erythematosus (SLE) using anti-CD48 antibodies
#11044Human antibodies to toxins
#11045Human antibodies that bind CD22 and uses thereof
#11046Assay method for Alzheimer's disease
#11047Anti-single-chain type IV collagen polypeptide antibody, pharmaceutical drug, diagnostic, preventive, or therapeutic drug for tumour containing the antibody
#11048CX3CR1-binding polypeptides comprising immunoglobulin single variable domains
#11049Antibodies to IL-6 to inhibit or treat inflammation
#11050Anti-C5a antibodies
#11051Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling
#11052Antibodies to hepatocyte growth factor activator
#11053Monoclonal antibodies against c-Met
#11054Humaneered anti-factor B antibody
#11055Anti-GD2 antibodies
#11056Antibodies that bind and block triggering receptor expressed on myeloid cells-1 (TREM-1)
#11057Antibodies that bind myostatin, compositions and methods
#11058Anti-tumor antigen antibodies and methods of use
#11059DKK1 antibodies and methods of use
#11060Fab-glycosylated antibodies
#11061Humanized anti-CDCP1 antibodies
#11062Antibodies directed toward the HIV-1 GP120 CD4 binding site with increased potency and breadth
#11063Anti-C-met antibody and methods of use thereof
#11064Compositions and methods for treating IgE-mediated disorders
#11065Compositions and methods for treating IgE-mediated disorders
#11066Library-based methods and compositions for introducing molecular switch functionality into protein affinity reagents
#11067Antibodies directed to αVβ6 and uses thereof
#11068Antibodies for the treatment of -associated infection and disease
#11069Anti-serum albumin binding variants
#11070Antibodies directed against IL-17
#11071Mice expressing a limited immunoglobulin light chain repertoire
#11072Humanized universal light chain mice
#11073Fibronectin binding domains with reduced immunogenicity
#11074Antibodies
#11075Human monoclonal antibody
#11076Anti-ASIC1 antibodies and uses thereof
#11077Human antibodies and uses therefor
#11078Anti-adrenomedullin (ADM) antibody or anti-ADM antibody fragment for use in therapy
#11079Anti-adrenomedullin (ADM) antibody or anti-ADM antibody fragment or anti-ADM non-IG scaffold for reducing the risk of mortality in a patient having a chronic or acute disease or acute condition
#11080Nucleic acid encoding and method of producing anti-IL-17A/IL-17F cross-reactive antibodies
#11081Antibody drug conjugates (ADC) that bind to 191P4D12 proteins
#11082Carrier immunoglobulins and uses thereof
#11083Monoclonal antibodies that specifically block biological activity of a tumor antigen
#11084Monoclonal antibodies against HER2
#11085Polynucleotides encoding an actriib antibody
#11086Antibodies to receptor for advanced glycation end products (RAGE) and uses thereof
#11087Humanized antibodies targeting the EC1 domain of Cadherin-11 and related compositions and methods
#11088Human tissue factor antibody and uses thereof
#11089Methods of inducing or enhancing an immune response in a subject by administering agonistic GITR binding antibodies
#11090Anti-LRP5 antibodies and methods of use
#11091FGFR4 antibodies
#11092Agonistic antibody to CD27
#11093High affinity antibodies that neutralize enterotoxin B
#11094Anti-CD19 antibody having ADCC function with improved glycosylation profile
#11095Cancer therapy using CLDN6 target-directed antibodies in vivo
#11096Anti-folate receptor alpha antibodies and uses thereof
#11097Antagonists of IL-6 to treat cachexia, weakness, fatigue, and/or fever
#11098Antagonists of IL-6 to raise albumin and/or lower CRP
#11099Soluble human ST-2 antibodies and assays
#11100PDGF receptor beta binding polypeptides