97307 ⎘
Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Dual variable domain immunoglobulins and uses thereof
#11702Antibodies against human tweak and uses thereof
#11703Anti-IL12Rbeta1 antibodies and their use in treating autoimmune and inflammatory disorders
#11704ANTAGONISTS OF PCSK9
#11705Antagonists of PCSK9
#11706CD33 binding agents
#11707Antibodies that specifically bind to A beta oligomers and use thereof
#11708ANTIBODY COMPOSITIONS AND METHODS OF USE
#11709OPTIMIZED ANTIBODIES THAT TARGET CD19
#11710ANTI-CMET ANTAGONISTS
#11711ANTI-CMET ANTAGONISTS
#11712Antibody drug conjugates (ADC) that bind to 191P4D12 proteins
#11713ANTAGONISTS OF PCSK9
#11714Anti-IL-6R polypeptides and pharmaceutical compositions thereof
#11715ANTIBODIES TO TROPONIN I AND METHODS OF USE THEREOF
#11716Human cytomegalovirus neutralising antibodies and use thereof
#11717ANTAGONISTS OF PCSK9
#11718Antibodies capable of blocking the interaction between CD48 and a CD48 receptor
#11719Generation and profiling of fully human HuCAL gold®-derived therapeutic antibodies specific for human CD3i
#11720Recombinant fusion protein and polynucleotide construct for immunotoxin production
#11721Antibody Constant Region Variant
#11722Antibody to human IL-3 receptor alpha chain
#11723RSV specific binding molecule
#11724Therapeutic use of anti-CS1 antibodies
#11725TREATMENT OF VASCULARIZED PIGMENT EPITHELIAL DETACHMENT WITH ANTI-VEGF THERAPY
#11726Test agent for visceral obesity and use thereof
#11727Antibody constant region variant
#11728Anti-5T4 antibodies and uses thereof
#11729Diagnostic antibody assay
#11730Enhanced Binding of Pro-Inflammatory Cytokines by Polysaccharide-Antibody Conjugates
#11731Therapeutic use of anti-CS1 antibodies
#11732Stable and soluble antibodies inhibiting TNFα
#11733Therapeutic use of anti-CS1 antibodies
#11734Therapeutic use of anti-CS1 antibodies
#11735Therapeutic use of anti-CS1 antibodies
#11736Monoclonal Antibodies to Hepatocyte Growth Factor
#11737Anti-VEGF antibody compositions and methods
#11738Human monoclonal antibodies against hendra and nipah viruses
#11739PSCA: prostate stem cell antigen and uses thereof
#11740Method for treating psoriatic arthritis by administering an anti-IL-12 antibody
#11741Combinatorial antibody libraries and uses thereof
#11742ANTI- INTEGRIN ANTIBODIES, COMPOSITIONS, METHODS AND USES
#11743Anti-VEGFR-3 antibody compositions
#11744Antibodies directed to HER-3 and uses thereof
#11745A-beta binding polypeptides
#11746FGFR1C ANTIBODY COMBINATIONS
#11747Tag peptide having a protease recognition sequence and use thereof
#11748Anti-VEGF-C antibodies and methods using same
#11749Human monoclonal antibodies to activin receptor-like kinase-1
#11750Antibodies Directed to Angiopoietin-2 And Uses Thereof
#11751High affinity human antibodies to human IL-4 receptor
#11752COMPOSITIONS AND METHODS OF USE FOR BINDING MOLECULES TO DICKKOPF-1 OR DICKKOPF-4 OR BOTH
#11753Methods of treatment using human antibody molecules for IL-13
#11754PERIPHERAL BLOOD SPARC BINDING ANTIBODIES AND USES THEREOF
#11755Anti-IL-6 antibodies, compositions, methods and uses
#11756Method of treating rheumatoid arthritis with an anti-IL-6R antibody
#11757Engineered anti-IL-13 antibodies, compositions, methods and uses
#11758Monoclonal antibodies that inhibit the wnt signaling pathway and methods of production and use thereof
#11759Humanized anti-CD70 binding agents and uses thereof
#11760Glioblastoma multiforme-reactive antibodies and methods of use thereof
#11761Use of IL-1beta compounds
#11762PD-1 antibodies and PD-L1 antibodies and uses thereof
#11763Anti-hemagglutinin antibody compositions and methods of use thereof
#11764Human binding molecules capable of neutralizing influenza virus H3N2 and uses thereof
#11765Streptavidin having low immunogenicity and use thereof
#11766Anti-amyloid antibodies
#11767HUMAN MONOCLONAL ANTIBODY AGAINST A COSTIMULATORY SIGNAL TRANSDUCTION MOLECULE AILIM AND PHARMACEUTICAL USE THEREOF
#11768Methods of treating lupus nephritis using antibodies against monocyte chemotactic proteins
#11769Anti-tenascin-C A2 antibodies and methods of use
#11770Nucleic acid molecules encoding neutralising antibodies having specificity for human IL-17
#11771ANTI-LYSOPHOSPHOLIPID ANTIBODY DESIGN USING ANTIBODY STRUCTURES
#11772Antibodies directed to angiopoietin-1 and angiopoietin-2 and uses thereof
#11773TLR3 binding agents
#11774Therapeutic antibodies binding IL12Rβ1
#11775Human Anti-IL-6 Antibodies With Extended In Vivo Half-Life And Their Use In Treatment Of Oncology, Autoimmune Diseases And Inflammatory Diseases
#11776Amyloid beta(1-42) oligomers, derivatives thereof and antibodies thereto, methods of preparation thereof and use thereof
#11777Dual variable domain immunoglobulins and uses thereof
#11778Expandable liquid volume in an LED bulb
#11779Humanized GM-CSF antibodies
#11780SOMATIC HYPERMUTATION SYSTEMS
#11781Frizzled-binding agents and their use in screening for WNT inhibitors
#11782Metalloproteinase 9 binding proteins
#11783Anti-RON antibodies
#11784ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9)
#11785HEPATITIS C VIRUS COMBINATION THERAPY
#11786HK1-BINDING PROTEINS
#11787Compositions and methods of use for antibodies of dickkopf-1
#11788Antibody to SOST peptides
#11789Recombinant anti-VLA4 antibody molecules
#11790Interleukin-1 Alpha Antibodies and Methods of Use
#11791Antibodies specifically binding to human TSLPR and methods of use
#11792Antibodies to the PcrV antigen of
#11793Anti-IL6/IL-6R antibodies
#11794High affinity human antibodies to human cytomegalovirus (CMV) gB protein
#11795Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (PCSK9)
#11796Methods of using antigen binding proteins to proprotein convertase subtilisin kexin type 9 (PCSK9)
#11797Antibodies relating to PIVKA-II and uses thereof
#11798Antibodies useful in passive influenza immunization
#11799Chimeric RGMa polypeptides
#11800Methods and compositions for liver cancer therapy
#11801Polynucleotides encoding antagonist antibodies against GDF-8
#11802Isolated nucleic acid encoding an antibody which specifically binds to PCSK9 and a host cell that produces the antibody
#11803Interleukin-1 alpha antibodies and methods of use
#11804Interleukin-1α antibodies and methods of use
#11805MODIFIED SINGLE DOMAIN ANTIGEN BINDING MOLECULES AND USES THEREOF
#11806Interleukin-1 alpha antibodies and methods of use
#11807Method of treating inflammatory eye disease with IL-1β binding antibodies
#11808Composition comprising antibodies to LINGO or fragments thereof
#11809Stable and soluble antibodies inhibiting VEGF
#11810DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF
#11811Methods of reducing CRP and/or increasing serum albumin in patients in need using IL-6 antibodies of defined epitopic specificity
#11812Method for reducing a level of LDL-cholesterol by an antibody that specifically binds to PCSK9
#11813Antibodies That Specifically Bind to DR3
#11814PREVENTION AND TREATMENT OF PAIN USING MONOCLONAL ANTIBODIES AND ANTIBODY FRAGMENTS TO LYSOPHOSPHATIDIC ACID
#11815Anti-dengue virus antibodies
#11816Prevention and treatment of pain using antibodies to lysophosphatidic acid
#11817Anti-BV8 antibodies and uses thereof
#11818LeY SPECIFIC BIOTHERAPEUTIC
#11819Antibody variants composition
#11820Alpha5-beta1 antibodies and their uses
#11821Complete human monoclonal IgG4lambda specific for CTLA-4 and uses thereof for detection of soluble CTLA-4 and isolation of regulatory cells
#11822Fibroblast growth factor receptor-3 (FGFR-3) inhibitors and methods of treatment
#11823Antibody neutralizers of human granulocyte macrophage colony stimulating factor
#11824Methods of using anti-CGRP antagonist antibodies
#11825METHODS OF TREATING BONE-LOSS DISORDERS USING A GM-CSF ANTAGONIST
#11826Optimized FC variants
#11827Methods of treating a disease with anti-C5 alpha antibodies
#11828Folate receptor 1 antibodies and immunoconjugates and uses thereof
#11829Anti-Aβ oligomer humanized antibody
#11830Anti-Aβ oligomer humanized antibody
#11831Humanized anti-IL-6 antibodies
#11832Antibodies to insulin-like growth factor I receptor
#11833High affinity antibodies to human IL-6 receptor
#11834Anti-cobra toxin antibody fragments and method of producing a VH library
#11835Wise binding agents and epitopes
#11836ANTI-LYMPHOTOXIN ANTIBODIES
#11837Method for treating muscular dystrophy using antagonist antibodies against GDF-8
#11838Immunoglobulins with reduced aggregation
#11839METHODS FOR GENERATING ANTI-IL-23 ANTIBODIES, COMPOSITIONS, METHODS AND USES
#11840Human monoclonal antibodies and methods for producing the same
#11841Recombinant anti-MUC1 antibodies
#11842Antibodies against tissue factor pathway inhibitor
#11843Humanized IL-25 antibodies
#11844INDUCTION OF MUCOSAL IMMUNE RESPONSES BY MUCOSAL DELIVERY PENTABODY COMPLEX (MDPC)
#11845Amino acid sequences directed against cellular receptors for viruses and bacteria
#11846Methods of use for an antibody against human frizzled receptors 1, 2. 5, 7 or 8
#11847Anti-DLL4 antibodies and uses thereof
#11848HUMANEERED ANTI-FACTOR B ANTIBODY
#11849IL-17A/F HETEROLOGOUS POLYPEPTIDES AND THERAPEUTIC USES THEREOF
#11850SPECIFIC BINDING PROTEINS AND USES THEREOF
#11851Method for Producing Proteins
#11852HER2 ANTIBODY COMPOSITIONS
#11853Rapid isolation of monoclonal antibodies from animals
#11854Effectors of PAR-2 Activation and Their Use in the Modulation of Inflammation
#11855NOTCH1 receptor antibodies and methods of treatment
#11856AGENTS FOR HCV TREATMENT
#11857Methods for treating conditions associated with MASP-2 dependent complement activation
#11858Antibodies and methods for treating estrogen receptor-associated diseases
#11859POLYPEPTIDES AND POLYNUCLEOTIDES, AND USES THEREOF AS A DRUG TARGET FOR PRODUCING DRUGS AND BIOLOGICS
#11860Isolated antibodies which bind to CXC chemokine receptor 4
#11861Identification and engineering of antibodies with variant FC regions and methods of using same
#11862CGRP antibodies
#11863Compositions and methods for the therapy and diagnosis of cytomegalovirus
#11864Epitopes
#11865Methods and compositions to treat and detect misfolded-SOD1 mediated diseases
#11866Anti-serum albumin binding variants
#11867Anti-FGFR2 antibodies
#11868ANTI-TNFR1 POLYPEPTIDES, ANTIBODY VARIABLE DOMAINS & ANTAGONISTS
#11869ANTI-PAMP THERAPEUTIC ANTIBODIES
#11870Stabilized polypeptide compositions
#11871Anti-serum albumin binding variants
#11872METALLOPROTEINASE 9 AND METALLOPROTEINASE 2 BINDING PROTEINS
#11873Human antibodies against tissue factor and methods of use thereof
#11874Methods of treating moderate to severe hidradenitis suppurativa with anti-TNF-alpha antibodies
#11875ANTI-CMET ANTAGONISTS
#11876Generation, expression and characterization of the humanized K33N monoclonal antibody
#11877Human anti TSHR antibodies
#11878Human anti-alpha-synuclein antibodies
#11879Human CTLA-4 antibodies and their uses
#11880Reagents and methods for detecting a polymorphic protein
#11881POLYPEPTIDE VARIANTS WITH ALTERED EFFECTOR FUNCTION
#11882Antibodies to human GDF8
#11883ANTIBODIES AS T CELL RECEPTOR MIMICS, METHODS OF PRODUCTION AND USES THEREOF
#11884Nucleic acids encoding anti-IL-6 antibodies of defined epitopic specificity
#11885Anti-human CLCP1 antibody and use thereof
#11886ISOFORM SPECIFIC ANTI-HER4 ANTIBODIES
#11887Bispecific antibodies
#11888Method of reducing pruritis using IL-31 monoclonal antibodies
#11889SPECIFIC BINDING PROTEINS AND USES THEREOF
#11890Diagnostic agent and therapeutic agent for pancreatic cancer
#11891Crystals and structure of a human IgG Fc variant with enhanced FcRn binding
#11892Alpha 1-antitrypsin compositions and methods of making and using same
#11893Lowered affinity antibodies and uses therefor
#11894Method for In Vitro Molecular Evolution of Protein Function
#11895Methods of generating libraries and uses thereof
#11896Methods of treatment using human anti-IL-23 antibodies
#11897High affinity antibodies against HMGB1 and methods of use thereof
#11898Production of heteromultimeric proteins
#11899Monoclonal antibodies against amyloid beta protein and uses thereof
#11900Antibodies against epidermal growth factor receptor (EGFR) and uses thereof
#11901TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASE
#11902BSA-specific antibodies
#11903Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates and methods of making said conjugates
#11904AGONIST ANTI-TRKC ANTIBODIES AND METHODS USING SAME
#11905Fully human anti-epidermal growth factor receptor antibodies
#11906IL-1 binding proteins
#11907Antibodies to human IL-22
#11908Compositions and methods of use of immunotoxins comprising ranpirnase (Rap) show potent cytotoxic activity
#11909Antibodies to CCR2
#11910Methods of treating TSLP-related inflammatory disorders
#11911Antibodies that bind human CD27 and uses thereof
#11912Antibodies that bind colony stimulating factor 1 receptor (CSF1R)
#11913Anti-PD-L1 antibodies and uses therefor
#11914Antibodies against vascular endothelial growth factor receptor-1
#11915Human cytomegalovirus neutralizing antibodies and use thereof
#11916Fully human influenza M2 specific antibodies
#11917ANTI-INTERFERON-ALPHA ANTIBODIES
#11918Anti-CD38 human antibodies and uses thereof
#11919Anti-NGF antibodies for the treatment of various disorders
#11920CELL-PENETRATING, SEQUENCE-SPECIFIC AND NUCLEIC ACID-HYDROLYZING ANTIBODY, METHOD FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
#11921Dual Variable Domain Immunnoglobulins and Uses Thereof
#11922ANTI-CD20 MONOCLONAL ANTIBODIES
#11923Recombinant antibodies against hepatitis C virus and methods of obtaining and using same
#11924BLOOD-BRAIN BARRIER TARGETING ANTIBODIES
#11925Anti-hepsin antibodies and methods using same
#11926Human antibodies that bind mesothelin, and uses thereof
#11927Human synthetic single-chain antibodies directed against the common epitope of mutant P53 and their uses
#11928USE OF IGF-II/IGF-IIE BINDING PROTEINS FOR THE TREATMENT AND PREVENTION OF SYSTEMIC SCLEROSIS ASSOCIATED PULMONARY FIBROSIS
#11929Anti-IL-12/IL-23 antibodies
#11930Antibodies specific to IL-17A and IL-17F
#11931Biological materials related to CXCR7
#11932IL-13 BINDING AGENTS
#11933NOVEL ANTIBODIES
#11934AMINO ACID SEQUENCES THAT MODULATE THE INTERACTION BETWEEN CELLS OF THE IMMUNE SYSTEM
#11935COMBINATION TREATMENTS COMPRISING PROTEASE BINDING PROTEINS FOR INFLAMMATORY DISORDERS
#11936Methods of treating chronic pain
#11937Soluble human ST-2 antibodies and assays
#11938High affinity human antibodies to human nerve growth factor
#11939Anti-ErbB3 antibodies
#11940CD37-binding molecules and immunoconjugates thereof
#11941Methods for treating hypercholesterolemia using antibodies to PCSK9
#11942Neuropilin antagonists
#11943NOVEL METHODS AND ANTIBODIES FOR TREATING CANCER
#11944Amyloid-beta binding proteins
#11945Pharmaceutical composition comprising a bispecific antibody for EpCAM
#11946Anti-polyubiquitin antibodies and methods of use
#11947MYOSTATIN BINDING PROTEINS
#11948Anti-LRP6 antibodies
#11949IL-17A/F Heterologous Polypeptides and Therapeutic Uses Thereof
#11950POLYPEPTIDES, ANTIBODY VARIABLE DOMAINS & ANTAGONISTS
#11951FUNCTIONAL HEAVY CHAIN ANTIBODIES, FRAGMENTS THEREOF, LIBRARY THEREOF AND METHODS OF PRODUCTION THEREOF
#11952Fc Variants with Optimized Properties
#11953Methods for producing soluble membrane-spanning proteins
#11954Variable domains of camelid heavy-chain antibodies directed against glial fibrillary acidic proteins
#11955Anti-sclerostin antibodies
#11956ANTI-CD5 ANTIBODIES
#11957Reagents, methods, and systems for detecting methicillin-resistant
#11958Antagonists of IL-6 to raise albumin and/or lower CRP
#11959TNF-α binding proteins
#11960Anti-IL-6 Receptor Antibody
#11961GENERATION OF ANTIBODIES TO AN EPITOPE OF INTEREST
#11962Specific delivery of agrochemicals
#11963Antibodies to LRP6
#11964Therapeutic use of specific ligand in MSRV associated diseases
#11965Antibody and uses thereof
#11966PEPTIDES CAPABLE OF BINDING TO SERUM PROTEINS AND COMPOUNDS, CONSTRUCTS AND POLYPEPTIDES COMPRISING THE SAME
#11967COMPOUND AND METHOD FOR REGULATING PLASMINOGEN ACTIVATION AND CELL MIGRATION
#11968Monoclonal antibodies against ANGPTL3
#11969Antibodies against CSF-1R
#11970Anti-inflammatory agents
#11971Anti-CD40 antibodies
#11972Anti-P-selectin antibodies and methods of using the same to treat inflammatory diseases
#11973Monoclonal antibodies against orthopoxviruses
#11974CDR-repaired antibodies
#11975METHODS OF GENERATING VARIANT PROTEINS WITH INCREASED HOST STRING CONTENT AND COMPOSITIONS THEREOF
#11976Humanized antibodies against monocyte chemotactic proteins
#11977IL-17A antibodies
#11978Bispecific, bivalent anti-VEGF/anti-ANG-2 antibodies
#11979Polypeptides and antibodies derived from chronic lymphocytic Leukemia cells and uses thereof
#11980Non-human mammals for the production of chimeric antibodies
#11981()
#11982Antibody variants with enhanced complement activity
#11983Hybrid antibodies
#11984Anti-PCSK9 antibodies with pH dependent antigen binding
#11985Methods using recombinant anti-epidermal growth factor receptor antibody compositions
#11986Hepatocyte growth factor (HGF) binding proteins
#11987PD-1 antibodies
#11988Anti-NR10 antibody and use thereof
#11989Material and methods for treating or preventing HER-3 associated diseases
#11990TREATMENT AND PROPHYLAXIS OF AMYLOIDOSIS
#11991Antibodies That Specifically Bind to Chemokine Beta-4
#11992BASIGIN BINDING PROTEINS
#11993LIGAND THAT HAS BINDING SPECIFICITY FOR IL-4 AND/OR IL-13
#11994Humanized C-kit antibody
#11995Monoclonal antibodies that react with the capsule of
#11996Compositions and methods relating to glucagon receptor antibodies
#11997TUMOR THERAPY WITH AN ANTI-VEGF ANTIBODY
#11998Internalizing ErbB2 antibodies
#11999ANTI-IL-6 ANTIBODIES, COMPOSITIONS, METHODS AND USES
#12000Chimeric, humanized, or human antibody 2A4