ACTIVE INGREDIENT COMBINATIONS COMPRISING PYRIDYLETHYLBENZAMIDES AND OTHER ACTIVE INGREDIENTS

Description

CROSS REFERENCE TO RELATED APPLICATIONS

This application is a Divisional of U.S. application Ser. No. 13/99,586, which is a National Stage of PCT/EP211/71418, filed Nov. 3, 211, which claims priority to European Application No. 1193335.6, filed Dec. 1, 21; and U.S. Provisional Application No. 61/419,438, filed Dec. 3, 21. The contents of each of these applications is hereby incorporated by reference.

The present invention relates to new active ingredient combinations which consist of fluopyram and other known active ingredients and which are very well suited to the control of animal pests, such as insects and/or unwanted acarids and/or nematodes, in foliar and soil application and/or in seed treatment, and also to the boosting of yields.

It is already nown that certain pyridylethylbenzamides possess fungicidal, insecticidal, and acaricidal and nematicidal properties.

WO 24/1688 describes pyridylethylbenzamides and their use as fungacjdes. The possibility of combining one or more of the disclosed pyridylethylbenzamide derivatives with other known fungicides, insecticides, nematicides or acaricides for the purpose of broadening the spectrum of activity is likewise described. The application, however, teaches neither which insecticidal mixing partners are suitable, nor the mixing ratio in which insecticides and pyridylethylbenzamide derivatives are combined with one another. WO 25/7791 teaches fungicidal compositions comprising at least one pyridylethylbenzamide, a fungicide and an inhibitor of electron transport in the respiratory chain of fungi. The patent application, however, does not mention any mixtures of pyridylethylbenzamides with insecticides. WO 28/3738 teaches fungicidal compositions comprising at least one pyridylethylbenzamide and an insecticide. A possible nematicidal action of the compositions is described in the application, but not explicitly for mixtures comprising N-{2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl] ethyl}-2-trifluoromethylbenzamide.

The activity of the active ingredients and active ingredient compositions described in the prior art is good, but is capable of improvement at low application rates in certain cases, especially in the context of nematode control.

The object on which the, present invention is based, therefore, is that of providing nematicidal, insecticidal and acaricidal active ingredient combinations having improved activity, especially with regard to nematodes.

It has now been found that active ingredient combinations comprising

(I-1) N-{2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl}-trifluoromethylbezamide of formula (I)

(fluopyrarn)

and also its N-oxides;

• and
• (II) at least one further active ingredient selected from the group consisting of fluensulfone (II-1), imicyafos (II-2), Bacillus subtilis (II-3), Bacillus subtilis strain QST 713 (Serenade™) (II-4), Paecilomyces lilacinus (II-5), Paecilomyces lilacinus strain 251 (Bioact™) (II-6), azadirachtin (II-7), thymol (II-8), Metarhizium anisopliae (II-9), Rhizobium spp. (II-10), Beauveria spp. (II-11), Verticillium spp. (II-12), Metschnikowia fructieola (II-13), Metschnikowia fructicola strain NRRL Y-30752. (II-14), Bacillus subtilis strain GB03 (II-15), Bacillus pumilus strain GB34 (II-16), Bacillus pumilus strain QST2808 (II-17), Bacillus amyloliquefaciens strain IN937a (II-18), Bacillus amyloliquefaciens strain FZB 42 (II-19), Myrothecium verrucaria strain AARC-0255 (II-20), pyrethrum (II-21), Cydia pomonolla granulosis virus (CpGV) (II-22), Metarhizium anisopliae strain F52 (II-23), arbuscular mycorrhiza fungus (II-24), Beauveria bassiana strain ATCC 74040 (II-25), Beauveria brorigniartii (II-26), Lecanicillium lecanii (also known as Verticillium lecanii) (II-27), Bacillus thuringiensis subsp. tenebrionis (II-28)
  are very well suited to the control of phytopathogenic fungi and animal pests, more particularly nematodes, in foliar and soil application, particularly in the context of seed treatment, and also to the boosting of yields.

The insecticides or active nematicidal ingredients of group (II) are selected from the group consisting of the following:

fluensulfone (II-1) known from WO-A 2001/002378

and/or

imicyafos (II-2) known from EP-A 0464830

and/or

Bacillus subtilis (II-3)

and/or

Bacillus subtilis strain QST 713 (II-4)

and/or

Paecilomyces lilacinus (II-5)

and/or

Paecilomyces ilacinus strain 251 (II-6)

and/or

azadirachtin (Cas-No 11141-17-b) (II-7)

and/or

Thymol (II-8)

and/or

Metarhizium anisopliae (II-9),

and/or

Rhizobium spp. (II-10),

and/or

Beauveria spp. (II-11),

and/or

Verticilliumspp (II-12)

and/or

Metschnikowia fructicola (II-13) known from Kurztman and Droby, System. Application Microbiol. (2001), 24, pp 395-399

and/or

Metschnikowia fructicola strain NRRL Y-30752, (II-14) known from US-B2 6,994,849

and/or

Bacillus subtilis strain GB03 (II-15) known under the name Kodiak™ marketed by Gustafson LLC and/or

Bacillus pumilus strain GB34 known under the name YieldShield™ marketed by Gustafson LLC

and/or

Bacillus pumilus strain QST2808 known under the name Sonata™ marketed by Agraquest

and/or

Bacillus amyloliquefaciens strain IN937a

and/or

Myrothecium vernacaria strain ARRC-0255 known under the name DiTera™ marketed by Valent BioSciences

and/or

pyrethrum (II-21)

and/or

Cydia pomonella granulosis virus (CpGV) (II-22)

and/or

Metathizium anisophae strain F52 (II-23)

and/or

arbuscular mycorrhiza fungus (II-24)

and/or

Beauveria bassiana strain ATCC 74040 nown under the name Naturalis®) (II-25)

and/or

Beauveria brongniartii (II-26)

and/or

Lecanicillium lecanii (formerly known as Verticillium lecanii) (II-27)

and/or

Bacillus thuringiensis subsp. t:nebrionis (II-28).

In one preferred embodiment of the invention the active ingredients of group (II) are selected from the group consisting of fluensulfone (II-1), imicyafos (II-2), Bacillus subtilis (II-3), Bacillus subtilis strain QST 713 (Serenade™) (II-4), Paecilomyces lilacinus (II-5), Paecilomyces lilacinus strain 251 (Bioact™) (II-6), azadirachtin (II-7), thymol (II-8), Metarhizium anisopliae (II-9), Rhizobium spp. (II-10), Beauveria spp. (II-11), Verticillium spp. (II-12), Metschnikowia fructicola (II-13), Metschnikowia fructicola strain NRRL Y-30752, (II-14).

In one preferred embodiment of the inventi0n the active ingredients of group (II) are selected from the group of bacteria consisting of Bacillus subtilis (II-3), Bacillus subtilis strain QST 713 (Serenade™) (II-4), Bacillus subtilis strain GB03 (II-15), Bacillus pumilus strain GB34 (II-16), Bacillus pumilus strain QST2808 (II-17), Bacillus amyloliquefaciens strain IN937a Rhizobium spp. (II-10), Bacillus thuringiensis subsp. tenebrionis (II-28).

In one preferred embodiment of the invention the active ingedients of group (II) are selected from the group of Bacillus species consisting of Bacillus subtilis (II-3), Bacillus subtilis strain QST 713 (Serenade™) (II-4), Bacillus subtilis strain GB03 (II-15), Bacillus pumilus strain GB34 (II-16), Bacillus pumilus strain QST2808 (II-17), Bacillus amyloliquefaciens strain IN937a (II-18) Bacillus thuringiensis subsp. tenebrionis (II-28).

In one preferred embodiment of the invention the active ingredients of group (II) are selected from the group of fungal species consisting of Paecilomyces lilacinus (II-5), Paecilomyces iilacinus strain 251 (Bloact™) (II-6), Metarhizium anisopliae (II-9), Beauveria spp. (II-11), Verticilliem spp. (II-12), Metschnikowia fructicola (II-13), Metschnikowia fructicola strain NRRL Y-30752. (II-14), Myrothecium verrucaria strain AARC-0255 (II-19), Metarhizium anisopliae strain F52 (II-23), arbuscular mycorrhiza fungus (II-24), Beauveria bassiana, in particular strain ATCC 74040 (II-25), Beauveria brongniartii (II-26), Lecanicillium lecanii (formerly known as Verticillium lecanii) (II-27).

In one preferred embodiment of the invention the active ingredients of group (II) are selected from the group consisting of fluensulfone (II-1), imicyafos (II-2), Paecilomyces lilacinus (II-5), Paecilomyces lilacinus strain 251 (Bioact™) (II-6), Metarhizium anisopliae (II-9), Metschnikowia fructicola (II-13), Metschnikowia fructicola strain NRRL Y-30752. (II-14), Bacillus subtilis strain GB03 (II-15), Bacillus amyloliquefaciens strain FZB 42 (II-19), Bacillus thuringiensis subsp. tenebrionis (II-28), pyrethrum (II-21), Cydia pomonella granulosis virus (CpGV) (II-22), Metarhizium anisopliae strain F52 (II-23), arbuscular mycorrhiza fungus (II-24).

In one preferred embodiment of the invention the active ingredients of group (II) are selected from the group consisting of fluensulfone (II-1), imicyafos (II-2), Bacillus subtilis (II-3), Bacillus subtilis strain QST 713 (Serenade™) (II-4), Paecilomyces lilacinus (II-5), Paecilomyces lilacinus strain 251 (Bioact™) (II-6) and also Metschnikowia fructicola (II-13).

In one particularly preferred embodiment of the invention the active ingredients of group (II) are selected from the group consisting of fluensulfone imicyafos (II-2), Bacillus subtilis strain QST 713 (Serenade™) (II-4), Paecilomyces lilacinus strain 251 (Bioact™) (II-6).

In one preferred embodiment of the invention the active ingredients of group (II) are selected from the group of the low molecular mass active ingredients fluensulfone (II-1), imicyafos (II-2), azadirachtin (II-7), thymol (II-8).

Surprisingly, the fungicidal, insecticidal and/or acaricidal and/or nematicidal action, more particularly the nematicidal action, of the active ingredient combinations of the invention, particularly after soil application, is substantially higher than the sum of the actions of the individual active ingredients. The effect is an unpredictable true synergistic effect, and not merely a supplementation of action. Moreover, the active ingredient combinations of the invention are suitable for effecting a boost to yield.

Preferred active ingredient combinations are those comprising the compounds of the formula (I-1) and at least one active ingredient of the formula (II).

Of particular interest are the following combinations:

(I-1)+(II-1), (I-1)+(II-2), (I-1)+(II-3), (I-1)+(II-4), (I-1)+(II-5), (I-1)+(II-6), (I-1)+(II-7), (I-1)+(II-8), (I-1)+(II-9), (I-1)+(II-10), (I-1)+(II-11), (I-1)+(II-12), (I-1)+(II-13), (I-1)+(II-14), (I-1)+(II-15), (I-1)+(II-16), (I-1)+(II-17), (I-1)+(II-18), (I-1)+(II-19), (I-1)+(II-20), (I-1)+(II-21), (I-1)+(II-22), (I-1)+(II-23), (I-1)+(II-24), (I-1)+(II-25), (I-1)+(II-26), (I-1)+(II-27), (I-1)+(II-28).

The active ingredient combinations may also, furthermore, comprise other, admix components with fungicidal, acaricidal, nematicidal or insecticidal activity.

If the active ingredients are present in particular weight ratios in the active ingredient combinations of the invention, the improved action is apparent with particular clarity. However, within the active ingredient combinations, the weight ratios of the active ingredients can be varied within a relatively wide range. In general the combinations of the invention comprise active ingredients of the formula (I-1) and the mixing partner in the preferred and particularly preferred mixing ratios indicated in the table below:

			Very particularly
Mixing	Preferred mixing ratio	Particularly preferred mixing	preferred mixing ratio
partner	(I-1):Mixing partner	ratio (I-1):Mixing partner	(I-1):Mixing partner
II-1	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-2	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-3	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-4	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-5	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-6	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-7	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-8	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-9	500:1 to 1:50000	125:1 to 1:12500	25:1 to 1:2500
II-10	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-11	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-12	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-13	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-14	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-15	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-16	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-17	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-18	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-19	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-20	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-21	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-22	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-23	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-24	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-25	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-26	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-27	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25
II-28	500:1 to 1:500	125:1 to 1:125	25:1 to 1:25

Animal Pests Pests

The active ingre combinations combine good tolerance by plants with suitability for controlling animal pests, such as insects and/or arachnids, and more particularly nematodes, which are prevalent in viticulture, fruit growing, agriculture, horticulture, and forestry. They can be used with preference as crop protection compositions. They are active against normally sensitive species and resistant species, and also against all or individual development stages. The aforementioned pests include the following:

Insects

Examples from the order of the noplura (Phthiraptera): Damalinia spp., Haematopinus spp., Linognathus spp., Pediculus spp., Trichodectes spp.

Examples from the class of the Arachnida: Acarus spp. Aceria sheidoni, Aculops spp., Aculus spp., Amblyomma spp., Amphitetranychus vietmensis, Argas spp., Boophilus spp., Brevipalpus spp., Bryobia praetiosa, Chorioptes spp., Dermanyssus gallinae, Eotetranychus spp., Epitrimerus pyri, Eutetranychus spp., Eriophyes spp., Halotydeus destructor, Hemitarsonemus spp., Hyalomma spp., Ixodes spp., Latrodectus mactans, Metatetranychus spp., Nuphersa spp., Oligonychus spp, Ornithodoros spp., Panonychus spp. Phyllocoptruta oleivora, Poivphagotarsonemus latus, Psoroptes spp., Rhipicephalus spp., Rhizoglyphus spp., Sarcoptes spp., Scorpio maurus, Stenotarsonemus spp., Tarsonemus spp., Tetranychus spp., Vasates lycopersici.

Examples from the class of the Bivalva: Dreissena spp.

Examples from the order of the Chilopoda: Geophilus spp., Scutigera spp.

Examples from the order of the Coleoptera: Acalymana vittatum, Acanthoscelides obtectus, Adoretus spp., Agelastica alni, Agriotes spp., Amphimallon solstitialis, Anobium punctatum, Anoplophora spp., Anthonomus spp., Anthrenus spp., Apion spp., Apogonia spp., Atomaria spp., Attagenus spp,, Bruchidius obtectus, Bruehus spp., Cassida spp., Cerotoma trifurcata, Ceutorrhynchus spp., Chaetocnema spp., Cleonus mendicus, Conoderus spp., Cosmopolites spp., Costelytra zealandica, Ctenicera spp., Curculio spp., Cryptorhynchus lapathi, Cylindrocopturus spp., Dermestes spp., Diabro-tica spp., Dichocrocis spp., Diloboderus spp., Epilachna spp., Epitrix spp., Faustinus spp., Gibbium psylioides, Hellula undalis, Heteronychus arator, Heteronyx. spp., Hylamorpha elegans, Hylotrupes bajulus, Hypera postica, Hypothenemus spp., Lachnosterna consanguinea, Lerna spp., Leptinotarsa decemlineata, Leucoptera spp., Lissorhoptrus oryzophilus, Lixus spp., Luperodes spp., Lyctus spp., Megascelis spp., Melanotus spp., Meligethes aeneus, Melolontha spp., Migdolus spp., Monochamus spp., Naupactus xanthographus, Niptus hololeucus, Oryctes rhinoceros, Oryzaephilus surinamensis, Oryzaphagus oryzae, Otiorrhynchus spp., Oxycetonia jueunda, Phaedon cochleariae, Phyllophaga spp., Phyliotreta spp., Popillia japonica, Premnotrypes spp., Psylliodes spp Ptinits spp., Rhizobius ventralis, Rhizopertha domntica, Sitophilus spp., Sphenophorus spp., Sternechus spp., Symphyletes spp., Tanymecus spp., Tenebrio molitor, Tribolium spp., Trogoderma spp., Tychius spp., Xylotrechus spp., Zabrus spp.

Example from the order of the Collembola: Onychiurus armatus.

Example from the order of the Diplopoda: Blaniulus guttulatus.

Examples from the order of the Diptera: Aedes spp., Agromyza spp., Anastrepha spp., Anopheles spp., Asphondylia spp., Bactrocera spp., Bibio hortulanus, Calliphora erythrocephala, Ceratitis capitata, Chironomus spp., Chrysomyia spp., Cochliomyia spp., Contarinia spp., Cordylobia anthropophaga, Culex spp., Cuterebra spp, Dacus oleae, Dasyneura spp., Delia spp., Dermatobia hominis, Drosophila spp., Echinocnemus spp., Fannia spp., Gastrophilus spp., Hydrellia spp., Hylemyia spp., Hyppobosca spp., Hypoderma spp, Liriomyza spp., Lucilia spp., Musca spp., Nezara spp., Oestrus spp., Oscinella frit, Pegomyia spp., Phorbia spp., Prodiplosis spp., Psila rosae, Rhagoletis spp., Stomoxys spp., Tabanus spp., Tannia spp., Tetanops spp., Tipula spp.

Examples from the class of the Gastropoda: Arlon spp., Biomphalaria spp., Bulinus spp., Deroceras spp.. Gallia spp., Lymnaea spp., Oncomelania spp., Pomacea spp., Succinea spp.,

Examples from the class of the heiminths: Ancylostoma duodenale, Ancylostoma ceylanicum, Acylostoma braziliensis, Ancylostoma spp., Ascaris lubricoides, Ascaris spp., Brugia Brugia timori, Bunostomum spp., Chabertia spp., Clonorchis spp., Cooperia spp., Dicrocoelium spp, Dictyocaulus filaria, Diphyllobothrium latum, Dracunculus medinensis, Echinococcus granulosus, Echinococcus multilocularis, Enterobius vermicularis, Faciola spp., Haemonchus spp., Heterakis spp., Hymenolepis nana, Hyostrongulus spp., Loa Loa, Nematodirus spp., Oesophagostomum spp., Opisthorchis spp., Onchocerca volvulus, Ostertagia spp., Paragonimus spp., Schistosomen spp, Strongyloides fuelleborni, Strongyloides stercoralis, Stronyloides spp., Taenia saginata, Taenia Trichinella spiralis, Trichinella nativa, Trichinella britovi, Trichinella nelsoni, Trichinella pseudopsiralis, Trichostrongulus spp., Trichuris triehuria, Wuchereria bancrofti.

It is also possible for protozoa, such as Eimeria, to be controlled.

Examples from the order of the Heteroptera: Anasa tristis, Antestiopsis spp., Blissus spp., Calocoris spp., Campylomma livida, Cavelerius spp., Cimex spp., Collaria spp., Creontiades dilutus, Dasynus piperis, Dichelops furcatus, Diconocoris hewetti, Dysdercus spp., Euschistus spp., Eurygaster spp., Heliopeltis spp., Horcias rtobilellus Leptocorisa spp., Leptogiossus phyllopus, Lygus spp., Macropes excavatus, Miridae, Monalonion atratum, Nezara spp., Oebalus spp., Pentomidae, Piesma quadrata, Piezodorus spp., Psallus spp., Pseudacysta persea, Rhodnius spp., Sahlbergella singularis, Scaptocoris castanea, Scotinophora spp., Stephanitis nashi, Tibraca spp., Triatoma spp.

Examples from the order of the Homoptera: Acyrthosipon spp., Acrogonia spp., Aeneolamia spp., Agonoscena spp., Aleurodes spp., Aleurolobus barodensis, Aleurothrixus spp., Amrasea spp., Anuraphis cardui, Aonidiella spp., Aphanostigma pin, Aphis spp., Arboridia apicalis, Aspidiella spp., Aspidiotus spp., Atanus sap., Aulacorthum solani, Bendsia spp., Braehycaudus helichrysii, Brachycolus spp., Brevicoryne brassicae, Calligypona marginata, Cameocephala fulgida, Ceratovacuna lanigera, Cereopidae, Ceroplastes spp., Chaetosiphon fragaefolii, Chionaspis tegalensis, Chlorita onukii, Chromaphis juglandicola, Chrysomphalus ficus, Cicadulina mbila, Coccomytilus halli, Coccus spp., Cryptomyzus ribis, Dalbulus spp., Dialeurodes spp., Diaphorina spp., Diaspis spp., Drosicha spp., Dysaphis spp., Dysmicoccus spp., Empoasca spp., Eriosoma spp., Erythroneura spp., Euscelis bilobatus, Ferrisia spp., Geococcus coffeae, Hieroglyphus spp., Homalodisca coagulata, Hyalopterus arundinis, Icenya spp., Idiocerus spp., Idioscopus spp., Laodelphax striatellus, Lecanium spp., Lepidosaphes spp., Lipaphis erysimi, Maerosiphum spp., Mahanarva spp., Melanaphis sacchari, Metcalfiella spp., Meto-poiophium dirhodum, Monellia costals, Mortelliopsis pecanis, Myzus spp., Nasonovia ribisnigri, Nephotettix spp., Nilaparvata lugens, Oncometopia spp., Orthezia praelonga, Parabemisia myricae, Paratrioza spp., Pariatoria spp., Pemphigus spp., Peregrinus maidis, Phenacoceus spp., Phloeomyzus passerinii, Phorodon humuli, Phylloxera spp., Pinnaspis aspidistrae, Planococcus spp., Protopulvinaria pyriformis, Pseudaulacaspis pentagons, Pseudococcus spp., Psylia spp., Pteromalus spp., Pyrilla spp., Quadraspidiotus spp., Quesada gigas, Rastrococcus spp., Rhopalosiphum spp., Saissetia spp., Scaphoides titanus, Sehizaphis graminum, Selenaspidus articulatus, Sogata spp., Sogatella fureifera, Sogatodes spp., Stictoeephala festina, Tenalaphara malayensis, Tinocallis earyaefoilae, Tomaspis spp., Toxoptera spp., Trialeurodes spp., Trioza spp., Typhlocyba spp., Unaspis spp., Viteus vitifolii, Zygina spp.

Examples from the order of the Hymenoptera: Athalia spp., Diprion spp., Hoplocampa spp., Lasius spp., Monomorium pharaonis, Vespa spp.

Examples from the order of the Isopoda: Armadillidium vulgare, Oniscus aseims, Porcellio scaber.

Examples from the order of the Isoptera: Aeromyrmex spp., Atta spp., Cornitermes cumulans, Microtermes ohesi, Odontotermes spp., Reticulitermes spp.

Examples from the order of the Lepidoptera: Acronicta major, Adoxophyes spp., Aedia leucomelas, Agotis spp., Alabama spp., Amyelois transitella, Anarsia spp., Anticarsia spp., Argyroploce spp., Barathra brassicae, Borbo cinnara, Bueculatrix thurberiella, Bupalus piniarius, Busseola spp., Cacoecia spp., Caloptilia theivora, Capua reticulana, Carpocapsa pomonella, Carposina niponensis, Cheimatobia brumata, Chilo spp., Choristoneura spp., Clysia ambiguella, Cnaphalocerus spp., Cnephasia spp., Conopomorpha spp., Conotrachelus spp., Copitarsia spp., Cydia spp., Dalaca noetuides, Diaphania spp., Diatraea saccharails, Earias spp., Ecdytolopha aurantium, Elasmopalpus lignoselius, Eldana saecharina, Ephestia kuehniella, Epinotia spp., Epiphyas postvittana, Etiella spp., Lelia spp., Eupoecilia ambiguella, Euproctis spp., Euxoa spp., Feltia spp., Galleria mellonella, Graeillarla spp., Grapholitha spp., Hedylepta spp., Helicoverpa spp., Heliothis spp., Hofmarmophila pseudospretella, Homoeosoma spp., Homona spp., Hyponomeuta padella, Kakiyoria flayofasciata, Laphygina spp., Laspeyresia molesta, Leucinodes orbonalis, Leueoptera spp., Lithoeolletis spp., Lithophane antennata, Lobesia spp., Loxagrotis abicosta, Lymantria spp., Lyonetia spp., Malaeosoma neustria, Maruca testulalis, Mamestra brassicae, Mocis spp., Lythimna separata, Nymphula spp., Oiketieus spp., Oria spp., Orthaga spp., Ostrinia spp., Oulerna oryzae, Panofts ilammea, Parnara spp., Pectinophora spp., Perileucoptera spp., Phthorimaea spp., Phylloenistis citrelia, Phyllonorycter spp., Pieris spp., Platynota stultana, Plusia spp., Plutella xylostella, Prays spp., Prodenia spp., Protoparee spp., Pseudaletia spp., Pseudoplusia includens, Pyrausta nubilalis, Rachiplusia nu, Schoenobius spp., Seirpophaga spp., Scotia segetum, Sesamia spp., Sparganothis spp., Spodoptera spp., Stathmopoda spp., Stomopteryx subsecivella, Synanthedon spp., Tecia solanivora, nemesia gemmatalis, Tinea pelli neila Tineola bisselliella, Tortrix spp., Trichoplusia spp., Tuta absoluta, Virachola spp.

Examples from the order of the Orthoptera: Acheta domesticus, Matta orientalis, Blattella germanica, Dichroplus spp., Gryllotalpa spp., Leueophaea maderae, Locusta spp., Melanoplus spp., Periplaneta americana, Schistocerca gregaria.

Examples from the order of Siphonaptera: Ceratophyllus spp., Xenopsylla cheopis.

Example from the order of the Symphyla: Scutigerella spp.

Examples from the order of the Thysanoptera: Anaphothrips obscurus, Baliothrips biformis, Drepanothris reuteri, Ermeothrips flavens, Frankliniella spp., Heliothrips spp., Hercinothsips femoralis, Rhipiphorothrips cruentatus, Scirtothrips spp., Taeniothrips cardamoni, Thrips spp.

Example from the order of the Thysanura: Lepisma saccharina.

Nematodes

All species of plant-parasitic nematodes may in principle be controlled using the active ingredient combinations of the invention. The active ingredient combinations of the invention prove particularly advantageous in the control of nematodes selected from the group consisting of the following: Aglerichus agricola, .:inguina tritici., Aphelenchoides arachidis, Aphelenchoides fragariae, Belonolaimus gracilis, Belonolaimus longicaudatus, Belonolaimus nortoni, Cacopaurus pestis, Criconemella curvata, Criconemella onoensis, Criconemella omata, Criconemella rusium, Criconemella xenoplax (=Mesocriconema xenoplax) and Criconemella spp. in general, Criconemoides ferniae, Criconemoides onoense, Criconemoides ornatum and Criconemoides spp. in general, Ditylenchus destructor, Ditylenchus dipsaci, Ditylenchus myceliophagus and Ditylenchus spp. in general, Dolichodorus heterocephalus, Globodera pallida (=Heterodera pallida), Globodera rostochiensis, Globodera solanacearum, Globodera tabacum, Globodera virginiae, Helicotylenchus digonicus, Helicotylenchus dihystera, Helicotylenchus erythrine, Helicotylenchus multicinctus, Helicotylenchus nannus, Helicotylenchus pseudorobustus and Helicotylenchus spp. in general, Hemicriconemoides, Hemicycliophora arenaria, Hemicycliophora nudata, Hemicycliophora parvana, Heterodera avenae, Heterodera cruciferae, Heterodera glycines, Heterodera oryzae, Heterodera schachtii, Heterodera zeae and Heterodera spp. in general, Hoplolaimus aegyptii. Hoplolaimus californicus, Hoplolaimus columbus, Hoplolaimus galeatus, Hoplolaimus indicus, Hoplolaimus magnistylus, Hoplolaimus pararobustus, Longidorus africanus, Longidorus breviannulatus, Longidorus elongatus, Longidorus laevicapitatus, Longidorus vineacola and Longidorus spp. in general, Meloidogyne acronea, Meloidogyne africana, Meloidogyne arenaria, Meloidogyne arenaria thamesi, Meloidogyne artiella, Meloidogyne chitwoodi, Meloidogyne coffeicola, Meloidogyne ethiopica, Meloidogyne exhzua, Meloidogyrie graminicola, Meloidogyne graminis, Meloidogyne hapla, Meloidogyrie incognita, Meloidogyne incognita acrita, Meloidogyne javanica, Meloidogyne kikuyensis, Meloidogyne naasi, Meloidogyne paranaensis, Meloidogyne thamesi and Meloidogyne spp. in general, Meloinema spp., Nacobbus aberrans, Neotylenchus vigissi, Paraphelenchus pseudoparietinus, Paratrichodorus allius, Paratrichodorus lobatus, Paratrichodorus minor, Paratrichodorus nasus, Paratrichodorus porosus, Paratrichodorus teres and Paratrichodorus spp. in general, Paratylenchus hamatus, Paratylenchus minutus, Paratylenchus projectus and Paratylenchus spp. in general, Pratylenchus agilis, Pratylenchus alleni, Pratylenchus andinus, Pratylenchus brachyurus, Pratylenchus cerealis, Pratylenchus coffeae, Pratylenchus crenatus, Pratylenchus delattrei, Pratylenchus gibbicaudatus, Pratylenchus goodeyi, Pratylenchus hamatus, Pratylenchus hexincisus, Pratylenchus loosi, Pratylenchus neglectus, Pratylenchus penetrans, Pratylenchus pratensis, Pratylenchus scribneri, Pratylenchus teres, Pratylenchus thomei, Pratylenchus vulnus, Pratylenchus zeae and Pratylenchus spp. in general, Pseudohalenchus rninutus, Psilenchus magnidens, Psilenchus tumidus, Punctodera chaicoensis, Quinisulcius acutus, Radopholus citrophilus, Radopholus similis, Rotylenchulus borealis, Rotylenchulus parvus, Rotylenchuhis reniformis and Rotylenchulus spp. in general, Rotylenchus laurentinus, Rotylenchus macrodoratus, Rotylenchus robustus, Rotylenchus uniformis and Rotylenchus spp. in general, Scutelionema brachyurum, Seutelionerna bradys, Scutellonema clathricaudatum and Seutelionema spp. in general, Subanguirta radiciola, Tetylertchus nicotianae, Trichodorus cylindricus, Trichodorus minor, Trichodorus primitius, Trichodorus proximus, Trichodorus similis, Trichodorus sparsus and Trichodorus spp. in general, Tylenchorhyncinis agri, Tylenchorhynchus brassicae, Tylenchorhynchus Tylenchorhynchus claytoni, Tylenchorhyrichus digitatus, Tylenehorhynchus ebriensis, Tylenchorhynchus maximus, Tylenchorhynchus nudus, Tylenchorhynchus vulgaris and Tylenchorhynchus spp. in general, Tylenchulus semipenetrans, Xiphinema americanum, Xiphinema brevicolle, Xiphinema dimorphicaudaturn, Xiphinema index and Xiphinema spp. in general.

The active ingredient combinations of the invention prove especially advantageous in, the control of nematodes selected from the group consisting of the following: Meloidogyne spp., such as Meloidogyne incognita, Meloidogyne javanica, Meloidogyne hapla, Meloidogyne arenaria; Ditylenchus ssp., such as Ditylenchus dipsaci, Ditylelenchus destructor; Pratylenchus ssp., such as Pratylenchus penetrans, Pratylenchus fallax, Pratylenchus coffeae, Pratylenchus loosi, Pratylenchus vulnus; Globodera spp., such as Globodera rostochiensis, Globodera pallida etc.; Heterodera spp. , such as Heterodera glycines Heterodera shachtoii etc.; Aphelenchoides spp., such as Aphelenchoides besseyi, Aphelenchoides ritzemabosi, Aphelenchoides fragarieae; Aphelenchus ssp., such as Aphelenchus avenae; Radopholus ssp, such as Radopholus similis; Tylenchulus ssp., such as Tylenchulus semipenetrans; Rotylenchulus ssp., such as Rotylenchulus reniformis;

Bursaphelenchus spp., such as Bursaphelenchus xyiophiius, Aphelenchoides spp., Longidorus spp., Xiphinema spp., Trichodorus spp.

Furthermore, the active ingredient combinations of the invention prove active in the control of nematodes which infect humans or animals, such as round worm, pin worm, filaria, Wuchereri bancrofti, thread worms (convoluted filaria), Gnathostoma etc.

Animal Health

The active ingredient combinations of the invention do not act only against plant, hygiene and stored product pests but also in the veterinary sector, against animal parasites (ecto- and endoparasites) such as hard ticks, soft ticks, mange mites, leaf mites, :flies (biting and licking), parasitic fly larvae, lice, hair lice, feather lice, and fleas. These parasites including the following:

Examples from the order of the Anophtrida: Haematopinus spp., Linognathus spp., Pediculus spp., Phtirus spp., Solenopotes spp.

Examples from the order of the Mallophagida and the suborders Arnblycerina and Ischnocerina: Trimenopon spp., Menopon spp., Trinoton spp., Bovicola spp., Werneckiella spp., Lepikentron spp., Damalina spp., Trichodectes spp., Felicola spp.

Examples from the order Diptera and the suborders Nematocerina and Brachycerina: Aedes spp., Anopheles spp., Culex spp., Simulium spp., Eusimulium spp., Phlebotomus spp., Lutzomyia spp., Culicoides spp., Chrysops spp., flybomitra spp., Atylotus spp., Tabanus spp., Haematopota spp., Philipomyia spp., Braula spp., Musca spp., Hydrotaea spp., Stomoxys spp., Haematobia spp., Morellia spp., Fannia spp., Glossina spp., Calliphora spp., Lucilia spp., Chrysomyia. spp., Wohlfahrtia spp., Sarcophaga spp., Oestrus spp., Hypodenna spp., Gasterophilus spp., Hippobosca spp., Lipoptena spp., Melophagus spp.

Examples from the order of the Siphonapterida: Pulex spp., Ctenocephalides spp., Xenopsylla spp., Ceratophyllus spp.

Examples from the order of the Heteropterida: Cimex spp., Triatoma spp., Rhodnius spp., Panstrongyhis spp.

Examples from the order of the Blattarida: Matta orientalis, Periplaneta americana, Blattela germanica, Supella spp.

Examples from the subclass of the Acari (Acarina) and from the orders of the Meta- and Mesostigmata: Argas spp., Ornithodorus spp., Otobius spp., Ixodes spp., Amblyomma spp., Boophilus spp., Dermacentor spp., Haemaphysalis spp., Hyalomma spp., Rhipicephalus spp., Dermanyssus spp., Raillietia spp., Pneurnonyssus spp., Sternostoma spp, Varroa spp.

Examples from the order of the Actinedida (Prostigmata) and Acaridida (stigmata): Acarapis spp., Cheyletiella spp., Ornithocheyletia spp., Myobia spp., Psorergates spp., Demodex spp., Trombicula spp., Listrophorus spp., Acarus spp., Tyrophagus spp., Caloglyphus spp., Hypodectes spp., Pterolichus spp., Psoroptes spp., Chorioptes spp., Otodectes spp., Sarcoptes spp., Notoedres spp., Knemidocoptes spp., Cytodites spp., Laminosioptes spp.

The active ingredient combinations of the invention are also suitable in the control of arthropods which infest agricultural livestock, such as cattle, sheep, goats, horses, pigs, donkeys, camels, buffalos, rabbits, chickens, turkeys, ducks, geese and bees, for example, other domesticated animals such as dogs, cats, caged birds and aquarium fish, for example, and also so-called experimentation animals, such as hamsters, guinea pigs, rats and mice, for example. The aim of controlling these arthropods is to reduce fatalities and yield reductions (of meat, milk, wool, hides, eggs, honey, etc,), so that more economic and easier animal husbandry is possible through the use of the active ingredient combinations of the invention.

Application of the active ingredient combinations of the invention in the veterinary sector and in animal husbandry is, in a conventional way, through enteral administration in the form of, for example, tablets, capsules, potions, drenches, granules, pastes, boluses, the feed-through method, and suppositories, and by parenteral administration, as for example through injections (intramuscular, subcutaneous, intravenous, intraperitoneal, etc.), implants, by nasal administration, by dermal application in the form, for example, of bathing or dipping, spraying, pour-on and spot-on, washing, and powdering, and also with the aid of molded articles containing active ingredient, such as collars, ear marks, tail marks, limb bands, halters, marking devices, etc.

In the context of application for livestock, poultry, domestic animals, etc., the active ingredient combinations may be applied as formulations (for example, powders, emulsions, Plowable compositions) which comprise the active ingredients in an amount from 1 to 80 wt. %, directly or after 100- to 10 000-fold dilution, or may be used in the form of a chemical bath.

Crops

The crops to be protected, which have only been described in a general manner, are differentiated and specified below. Thus, with regard to use, vegetables are understood to mean, for example, fruit vegetables and flower-heads as vegetables, for example carrots, bell peppers, chilli peppers, tomatoes, aubergines, cucumbers, cucurbits, courgettes, broad beans, runner beans, bush beans, peas, artichokes, maize;

but also leafy vegetables, for example lettuce, chicory, endives, cress, rocket salad, field salad, iceberg lettuce, leek, spinach, swiss chard;

additionally tuber vegetables, root vegetables and stern vegetables, for example celeriac, beetroot, carrots, garden radish, horseradish, salsity, asparagus, table beet, palm shoots, bamboo shoots, and also bulb vegetables, for example onions, leek, fennel, garlic;

additionally brassica vegetables, such as cauliflower, broccoli, kohlrabi, red cabbage, white cabbage, green cabbage, savoy cabbage, brussels sprouts, chinese cabbage.

With regard to use, perennial crops are unclerstood to mean citrus fruit for example oranges, grapefruit, mandarins, lemons, limes, bitter oranges, kumquats, satsumas;

but also pome fruit, for example apples, pears and quince, and stone fruit, for example peaches, nectarines, cherries, plums, common plums, apricots;

additionally grapevine, hops, olives, tea, soya, oilseed rape, cotton, sugar cane, beet, potatoes, tobacco and tropical crops, for example mangoes, papayas, figs, pineapples, dates, bananas, durians, kakis, coconuts, cacao, coffee, avocados, lychees, maracujas, guavas,

and also lmonds and nuts,for example hazelnuts, walnuts, pistachios, cashew nuts, brazil nuts,pecan nuts, butter nuts, chestnuts, hickory nuts, macadamia nuts, peanuts,

and additionally also soft fruit, for example blackcurrants, gooseberries, raspberries, blackberries, blueberries, strawberries, red bilberries, kiwis, cranberries.

With regard to use, ornamental plants are understood to mean annual and perennial plants, for example cut flowers, for example roses, carnations, gerbera, lilies, marguerites, chrysanthemums, tulips, daffodils, anemones, poppies, amaryllis, dahlias, azaleas, maives, but also, for example, bedding plants, potted plants and shrubs, for example roses, tagetes, pansies, geraniums, fuchsias, hibiscus, chrysanthemums, busy lizzies, cyclamen, african violets, sunflowers, begonias, in ornamental lawns, in golf lawns, but also in cereals such as barley, wheat, rye, triticale, oats, in rice, in millet, in maize,

additionally, for example, bushes and conifers, for example fig trees, rhododendron, spruce trees, fir trees, pine trees, yew trees, juniper trees, stone pines, rose bays.

With regard to use, spices are understood to mean annual and perennial plants, for example aniseed, chili pepper, bell pepper, pepper, vanilla, marjoram, thyme, cloves, juniper berries, cinnamon, tarragon, coriander, saffron, ginger.

The crops to be protected are highlighted in particular as follows: bell peppers, chilli peppers tomatoes, aubergines, cucumbers, cucurbits, courgettes, artichokes, maize, celeriac, beetroot, carrots, garden radish, horseradish, salsifies, asparagus, table beet, palm shoots, bamboo shoots, onions, leek, oranges, grapefruit, mandarins, lemons, limes, bitter oranges, kumquats, satsumas, apples, pears, and quince, and stone fruit, such as, for example, peaches, nectarines, cherries, plums, common plums, apricots, grapevine, hops, soya, oilseed rape, cotton, sugar cane, beet, potatoes, tobacco, hazelnuts, walnuts, pistachios, cashew nuts. brazil nuts, pecan nuts, butter nuts, chestnuts, hickory nuts, macadamia nuts, peanuts, roses, carnations, gerbera, lilies, marguerites, chrysanthemums, tulips, daffodils, anemones, poppies, amaryllis, dahlias, azaleas, malves, barley, wheat, rye, triticale, oats, rice, millet, maize.

According to the invention, it is possible to treat all plants and plant parts. Plants are understood here to mean all plants and plant populations such as desired and undesired wild plants or crop plants (including naturally occurring crop plants). Crop plants may be plants which can be obtained by conventional breeding and optimization methods or by biotechnological and genetic engineering methods or combinations of these methods, including the transgenic plants and including the plant cultivars which can or cannot be protected by plant breeders' certificates.

CMOs

In a further preferred embodiment, transgenic plants and plant cultivars which have been obtained by genetic engineering methods, if appropriate in combination with conventional methods (Genetically Modified Organisms), and parts thereof are treated. The terms “parts” and “plant parts” have been explained above,

More preferably, plants of the plant cultivars which are in each case commercial) ailable or in use are treated in accordance with the invention.

Depending on the plant species or plant cultivars, their location and growth conditions (soils, climate, vegetation period, nutrition), the treatment in accordance with the invention may also result in superadditive (“synergistic”) effects. For example, reduced application rates and/or a widening of the activity spectrum and/or an increase in the activity of the substances and compositions which can be used in accordance with the invention, better plant growth, increased tolerance to high or low temperatures increased tolerance to drought or to water or soil salt content, increased flowering performance, easier harvesting, accelerated maturation, higher harvest yields, better quality and/or higher nutritional value of the harvested products, better storage qualities and/or processability of the harvested products are possible which exceed the effects which were actually to be expected.

According to the invention all plants and plant parts can be treated. By plants is meant all plants and plant populations such as desirable and undesirable wild plants, cultivars and plant varieties (whether or not protectable by plant varietal property or plant breeder's rights). Cultivars and plant varieties can be plants obtained by conventional propagation and breeding methods which can be assisted or supplemented by one or more biotechnological methods such as by use of double haploids, protoplast fusion, random and directed mutagenesis, molecular or genetic markers or by bioengineering and genetic engineering methods. By plant parts are meant all above-ground and below-ground parts and organs of plants such as shoot, leaf, blossom and root, where for example leaves, needles, stems, branches, flowers, fruiting bodies, fruits and seed and also roots, corms and rhizomes are listed. Crops and vegetative and generative propagating material, for example cuttings, corms, rhizones, runners and seeds, also belong to plant parts.

Among the plants that can be protected by the method according to the invention, mention may be made of major field crops such as maize, soya bean, cotton, Brassica oilseeds such as Brassica napus (e.g. canola), Brassica rapa, B. juncea (e.g. mustard) and Brassica carinata, rice, wheat, sugar beet, sugar cane, oats, rye, barley, millet, triticale, flax, vine and various fruits and vegetables of various botanical taxa such as Rosaceae sp. (for instance pone fruit such as apples and pears, but also stone fruit such as apricots, cherries, almonds and peaches, soft fruits such as strawberries), Ribesioidae sp., Juglandaceae sp., Betulaceae sp., Anacardiaceae sp., Fagacette sp., Moraceae sp., Oleaceae sp., Actinidaceae sp., Lauraceae sp., Musaceae sp. (for instance banana trees and plantings), Rubiaceae sp. (for instance coffee), Theaceae sp., Sterculiceae sp., Rutaceae sp. (for instance lemons, oranges and grapefruit); Solanaceae sp. (for instance tomatoes, potatoes, peppers, eggplant), Liliaceae sp., Compositiae sp. (for instance lettuce, artichoke and chicory—including root chicory, endive or common chicory), Umbelliferae sp. (for instance carrot, parsley,celery and celeriac), Cucurbitaceae sp. (for instance cucumber including pickling cucumber, squash, watermelon, gourds and melons), Alliaceae sp. (for instance onions and leek), Cruciferae sp. (for instance white cabbage, red cabbage, broccoli, cauliflower, brussel sprouts, pak choi, kohlrabi, radish, horseradish, cress, Chinese cabbage), Leguminosae sp. (for instance peanuts, peas and beans such as climbing beans and broad beans), Chenopodiaceae sp. (for instance Swiss chard, white cabbage spinach, beetroots), Malvaceae (for instance okra), Asparagaceae (for instance asparagus) horticultural and forest crops; ornamental plants; and also genetically modified homologs of these crops.

The method of treatment according to the invention can be used in the treatment of genetically modified organisms (GMOs), e.g. plants or seeds. Genetically modified plants (or transgenic plants) are plants of which a heterologous gene has been stably integrated into the genome. The expression “heterologous gene” essentially means a gene which is provided or assembled outside the plant and when introduced in the nuclear, chloroplastic or mitochondrial genome gives the transformed plant new or improved agronomic or other properties by expressing a protein or polypeptide of interest or by down:regulating or silencing other gene(s) Which are present in the plant (using, for example, antisense technology, cosuppression technology or RNA interference—RNAi—technology). A heterologous gene that is located in the genome is also called a transgene. A transgene that is defined by its particular location in the plant genome is called a transformation event or transgenic event.

Depending on the plant species or plant cultivars, their location and growth conditions (soils, climate, vegetation period, nutrition), the treatment according to the invention may also result in superadditive (“synergistic”) effects. Thus, for example, reduced application rates and/or a widening of the activity spectrum and/or an increase in the activity of the active compounds and compositions which can be used according to the invention, better plant growth, increased tolerance to high or low temperatures, increased tolerance to drought or to water or soil salt content, increased flowering performance, easier harvesting, accelerated maturation, higher harvest yields, bigger fruits, larger plant height, greener leaf color, earlier flowering, higher quality and/or a higher nutritional value of the harvested products, higher sugar concentration within the fruits, better storage qualities and/or processability of the harvested products are possible, which exceed the effects which were actually to be expected.

At certain application rates, the active ingredient combinations according to the invention may also have a strengthening effect in plants. Accordingly, they are suitable for mobilizing the defense system of the plant against attack by unwanted microorganisms. This may, if appropriate, be one of the reasons of the enhanced activity of the combinations according to the invention, for example against fungi. Plant-strengthening (resistance-inducing) substances are to be understood as meaning, in the present context, also those substances or combinations of substances which are capable of stimulating the defense system of plants in such a way that, when subsequently inoculated with unwanted microorganisms, the treated plants display a substantial degree of resistance to these microorganisms. In the present case, unwanted microorganisms are to be understood as meaning phytopathogenic fungi, bacteria and viruses. Thus, the substances according to the invention can be employed for protecting plants against attack by the abovementioned pathogens within a certain period of time after the treatment. The period of time within which protection is effected generally extends from 1 to 10 days, preferably 1 to 7 days, after the treatment of the plants with the active ingredients.

Plants and plant cultivars which are preferably treated according to the invention include all plants which have genetic material which imparts particularly advantageous, useful traits to these plants (whether obtained by breeding and/or biotechnological means).

Plants and plant cultivars which are also preferably treated according to the invention are resistant against one or more biotic stresses, i.e. said plants show a better defense against animal and microbial pests, such as against nematodes, insects, mites, phytopathogenic fungi, bacteria, viruses and/or viroids.

For example, examples of :nematode-resistant plants are described in U.S. patent application Ser. Nos. 11/765,491, 11/765,494, 10/926,819, 10/782,020, 12/032,479, 10/783,417, 10/782,096, 11/657,964, 12/192,904, 11/396,808, 12/166,253, 12/166,239, 12/166,124, 12/166,209, 11/762,886, 12/364,335, 11/763,947, 12/252,453, 12/209,354, 12/491,396 or 12/497,221.

Plants and plant cultivars which may also be treated according to the invention are those plants which are resistant to one or more abiotic stresses. Abiotic stress conditions may include, for example, drought, cold temperature exposure, heat exposure, osmotic stress, flooding, increased soil salinity, increased mineral exposure, ozone exposure, high light exposure, limited availability of nitrogen nutrients, limited availability of phosphorus nutrients, or shade avoidance.

Plants and plant cultivars which may also he treated according to the invention are those plants characterized by enhanced yield characteristics. Increased yield in said plants can be the result of, for example, improved plant physiology, growth and development, such as water use efficiency, water retention efficiency, improved nitrogen use, enhanced carbon assimilation, improved photosynthesis, increased germination efficiency and accelerated maturation. Yield can furthermore be affected by improved plant architecture (under stress and non-stress conditions), including early flowering, flowering control for hybrid seed production, seedling vigor, plant size, internode number and distance, root growth, seed size, fruit size, pod size, pod or ear number, seed number per pod or ear, seed mass, enhanced seed filling, reduced seed dispersal, reduced pod dehiscence and lodging resistance. Further yield traits include seed composition, such as carbohydrate content, protein content, oil content and composition, nutritional value, reduction in anti-nutritional compounds, improved processability and better storage qualities.

Examples of plants with the above-menti) tned traits are non-exhaustively listed in table A.

Plants that may be treated according to the invention are hybrid plants that already express the characteristics of heterosis or hybrid vigor which results in generally higher yield and vigor, and improved health and resistance toward biotic and abiotic stresses. Such plants are typically made by crossing an inbred male-sterile parent line (the female parent) with another inbred male-fertile parent line (the male parent). Hybrid seed is typically harvested from the male-sterile plants and sold to growers. Male-sterile plants can sometimes (e.g. in maize) be produced by detasseling, i.e. the mechanical removal of the male reproductive organs (or male flowers) but, more typically, male sterility is the result of genetic determinants in the plant genome. In that case, and especially when seeds are the desired product to be harvested from the hybrid plants it is typically useful to ensure that male fertility in the hybrid plants is hilly restored. This can be accomplished by ensuring that the male parents have appropriate fertility restorer genes which are capable of restoring the male fertility in hybrid plants that contain the genetic determinants responsible for male sterility. Genetic determinants for male sterility may be located in the cytoplasm. Examples of cytoplasmic male sterility (CMS) have for example been described in Brassica species (WO 92/05251, WO 95/09910, WO 98/27806, WO 05/002324, WO 06/021972 and U.S. Pat. No. 6,229,072). However, genetic determinants for male sterility can also be located in the nuclear genome. Male-sterile plants can also be obtained by plant biotechnology methods such as genetic engineering. A particularly useful means of obtaining male-sterile plants is described in WO 89/10396 in which, for example, a ribonuclease such as a barnase is selectively expressed in the tapetum cells in the stamens. Fertility can then be restored by expression in the tapetum cells of a ribonuclease inhibitor such as harstar (e.g. WO 91/02069).

Plants or plant cultivars (obtained by plant biotechnology methods such as genetic engineering) which may be treated according to the invention are herbicide-tolerant plants, i.e. plants made tolerant to one or more given herbicides. Such plants can he obtained either by genetic transformation or by selection of plants containing a mutation imparting such herbicide tolerance.

Herbicide-resistant plants are for example glyphosate-tolerant plants, i.e. plants made tolerant to the herbicide glyphosate or salts thereof. Plants can be made tolerant to glyphosate through different means. For example, glyphosate-tolerant plants can be obtained by transforming the plant with a gene encoding the enzyme 5-enolpyruvyishikimate-3-phosphate synthase (EPSPS). Examples of such EPSPS genes are the AroA gene (mutant CT7) of the bacterium Salmonella typhimurium (Comai et al., Science (1983), 221, 370-371), the CP4 gene of the bacterium Agrobacterium sp. (Barry et al., Curr. Topics Plant Physiol. (1992), 7, 139-145), the genes encoding a petunia EPSPS (Shah et al., Science (1986), 233, 478-481), a tomato EPSPS (Gasser et al., J. Biol. Chem. (1988), 263, 4280-4289), or an eleusine EPSPS (WO 01/66704). It can also be a mutated EPSPS as described for example in EP 0837944, WO 00/66746, WO 00/66747 or WO 02/26995. Glyphosate-tolerant plants can also be obtained by expressing a gene that encodes a glyphosate oxido-reductase enzyme as described in U.S. Pat. Nos 5,776,760 and 5,463,175. Glyphosate-tolerant plants can also be obtained by expressing a gene that encodes a glyphosate acetyl transferase enzyme as described in for example WO 02/036782, WO 03/092360, WO 05/012515 and WO 07/024782. Glyphosate-tolerant plants can also be obtained by selecting plants containing naturally occurring mutations of the above-mentioned genes, as described in for example WO 01/024615 or WO 03/013226. Plants expressing EPSPS genes that confer glyphosate tolerance are described in e.g. U.S. patent application Ser. Nos. 11/517,991, 10/739,610, 12/139,408, 12/352,532, 11/312,866, 11/315,678, 12/421,292, 11/400,598, 11/651,752, 11/681,285, 11/605,824, 12/468,205, 11/760,570, 11/762,526, 11/769,327, 11/769,255, 11/943801 or 12/362,774. Plants comprising other genes that confer glyphosate tolerance, such as decarboxylase genes, are described in e.g. U.S. patent application Ser. Nos 11/588,811, 11/185,342, 12/364,724, 11/185,560 or 12/423,926.

Other herbicide-resistant plants are for example plants that have been made tolerant to herbicides inhibiting the enzyme glutamine synthase, such as bialaphos, phosphinothricin or glufosinate. Such plants can be obtained by expressing an enzyme detoxifying the herbicide or a mutant glutamine synthase enzyme that is resistant to inhibition, e.g. described in U.S. patent application Ser. No. 11/760,602. One such efficient detoxifying enzyme is for example an enzyme encoding a phosphinothricin acetyltransferase (such as the bar or pat protein from Streptomyces species). Plants expressing an exogenous phosphinothricin acetyltransferase are for example described in U.S. Pat. Nos. 5,561,236; 5,648,477; 5,646,024; 5,273,894; 5,637,489; 5,276,268; 5,739,082; 5,908,810 and 7,112,665.

Further herbicide-tolerant plants are also plants that have been made tolerant to the herbicides inhibiting the enzyme hydroxyphenylpyruvatedioxygenase (HPPD). HPPD is an enzyme that catalyses the reaction in which para-hydroxyphenylpyruvate (HPP) is transformed into homogentisate. Plants tolerant to HPPD-inhibitors can be transfof used with a gene encoding a naturally occurring resistant HPPD enzyme, or a gene encoding a mutated or chimeric HPPD enzyme as described in WO 96/38567, WO 99/24585 and WO 99/24586. Tolerance to HPPD-inhibitors can also be obtained by transforming plants with genes encoding certain enzymes enabling the formation of homogentisate despite the inhibition of the native HPPD enzyme by the HPPD-inhibitor. Such plants and genes are described in WO 99/34008 and WO 02/36787. Tolerance of plants to EIPPD inhibitors can also be improved by transforming plants with a gene encoding an enzyme having prephenate dehydrogenase (PDH) activity in addition to a gene encoding an HPPD-tolerant enzyme, as described in WO 2004/024928. Further, plants can be made more tolerant to HPPD-inhibitor herbicides by adding into their genome a gene encoding an enzyme capable of metabolizing or degrading HPPD inhibitors, such as the CYP450 enzymes shown in WO 2007/103567 and WO 2008/150473.

Still further herbicide-resistant plants are plants that have been made tolerant to acetolactate synthase (ALS) inhibitors. Known ALS inhibitors include, for example, sulfonylurea, imidazolinone, triazolopyrimidine, pyrimidinyloxy(thio)benzoate and/or sulfonylaminocarbonyltriazolinone herbicides. Different mutations in the ALS enzyme (also known as acetohydroxy acid synthasekHAS) are known to confer tolerance to different herbicides and groups of herbicides, as described for example in Tranel and Wright, Weed Science (2002), 50, 700-712), but also, in U.S. Pat. Nos 5,605,011, 5,378,824, 5,141,870 and 5,013,659. The production of sulfonylitrea-tolerant plants and imidazolinone-tolerant plants is described in U.S. Pat. Nos. 5,605,011; 5,013,659; 5,141,870; 5,767,361; 5,731,180; 5,304,732; 4,761,373; 5,331,107; 5,928,937; and 5,378,824; and international publication WO 96/33270. Other imidazolinone-tolerant plants are also described in for example WO 2004/040012, WO 2004/106529, WO 2005/020673, WO 2005/093093, WO 2006/007373, WO 2006/015376, WO 2006/024351 and WO 2006/060634. Further sulfonylurea- and imidazolinone-tolerant plants are also described in for example WO 07/024782 and U.S. patent application No. 61/288,958.

Other plants tolerant to imidazolinone and/or sulfonylurea can be obtained by induced mutagenesis, selection in cell cultures in the presence of the herbicide or mutation breeding as described for example for soya beans in U.S. Pat. No. 5,084,082, for rice in WO 97/41218, for sugar beet in U.S. Pat. No. 5,773,702 and WO 99/057965, for lettuce in U.S. Pat. No. 5,198,599 or for sunflower in WO 01/065922.

Plants or plant cultivars (obtained by plant biotechnology methods such as genetic engineering) which may also be treated according to the invention are insect-resistant transgenic plants, i.e. plants made resistant to attack by certain target insects. Such plants can be obtained by genetic transformation, or by selection of plants containing a mutation imparting such insect resistance.

An “insect-resistant transgenic plant”, as used herein, includes any plant containing at least one transgene comprising a coding sequence encoding:

• • 1) an insecticidal crystal protein from Bacillus thuringiensis or an secticidal portion thereof, such as the insecticidal crystal proteins listed by Crickmore et al., Microbiology and Molecular Biology Reviews (1998), 62, 807-813, updated by Crickmore et al. (2005) in the Bacillus thuringiensis toxin nomenclature, online at: http:/www.lifesci.sussex.ac.uk/Home/Neil_Crickmore/Btl), or insecticidal portions thereof, e.g., proteins of the Cry protein classes Cry1Ab, Cry1Ac, Cry1B, Cry1C, Cry1D, Cry1F, Cry2Ab, Cry3Aa or Cry3Bb or insecticidal portions thereof (e.g. EP-A 1999141 and WO 2007/107302), or such proteins encoded by synthetic genes as for example described in U.S. patent application Ser. No. 12/249,016; or
  • 2) a crystal protein from Bacillus thuringiensis or a portion thereof which is insecticidal in the presence of a second other crystal protein from Bacillus thuringiensis or a portion thereof, such as the binary toxin made up of the Cry34 and Cry35 crystal proteins (Moellenbeck et al., Nat. Biotechnol. (2001), 19, 668-72; Schnepf et al., Applied Enviromn. Microbiol. (2006), 71, 1765-1774) or the binary toxin made up of the Cry1A or Cry1F proteins and the Cry2Aa or Cry2Ab or Cry2Ae proteins (U.S. patent application Ser. No. 12/214,022 and EP 08010791.5); or
  • 3) a hybrid insecticidal protein comprising parts of two different insecticidal crystal proteins front Bacillus thuringiensis, such as a hybrid of the proteins of 1) above or a hybrid of the proteins of 2) above, e.g. the CrylA.105 protein produced by corn event MON89034 (WO 2007/027777); or
  • 4) a protein of any one of 1) to 3) above wherein some, particularly 1 to 10, amino acids have been replaced by another amino acid to obtain a higher insecticidal activity to a target insect species, and/or to expand the range of target insect species affected, and/or because of changes induced in the eneodirtu DNA during cloning or transformation, such as the Cry3Bb1 protein in corn events MON863 or MON88017, or the Cry3A protein in corn event MIR604; or
  • 5) an insecticidal secreted protein Bacillus thuringiensis or from Bacillus cereus, or an insecticidal portion thereof, such as the vegetative insecticidal (VIP) proteins listed at: http://www.lifesci.sussex.ac.uk/home/Neil_Crickmore/Bt/vip.html, e.g., proteins from the VIP3Aa protein class; or
  • 6) a secreted protein from Bacillus thuringiensis or Bacillus cereus which is insecticidal in the presence of a second secreted protein front Bacillus thuringiensis or B. cereus, such as the binary toxin made up of the VIP1A and VIP2A proteins (WO 94/21795) or
  • 7) a hybrid insecticidal protein comprising parts from different secreted proteins from Bacillus thuringiensis or Bacillus cereus, such as a hybrid of the proteins in 1) above or a hybrid of the proteins in 2) above; or
  • 8) a protein of any one of 5) to 7) above wherein some, particularly 1 to 10, amino acids have been replaced by another amino acid to obtain a higher insecticidal activity to a target insect species, and/or to expand therange of target insect species affected, and/or because of changes introduced into the encoding DNA during cloning or transformation (while still encoding an insecticidal protein), such as the VIP3Aa protein in cotton event COT 102; or
  • 9) a secreted protein from Bacillus thuringiensis or Bacillus cereus which is insecticidal in the presence of a crystal protein from Bacillus thuringiensis, such as the binary toxin made up of VIP3 and Cry1A or Cry1F (U.S. patent application Nos. 61/126,083 and 61/195,019), or the binary toxin made up of the VIP3 protein and the Cry2Aa or Cry2Ab or Cry2Ae proteins (U.S. patent application Ser. No. 12/214,022 and EP 08010791.5); or
  • 10) a protein of 9) above wherein some, particularly 1 to 10, amino acids have been replaced by another amino acid to obtain a higher insecticidal activity to a target insect species, and/or to expand the range of target insect species affected, and/or because of changes introduced into the encoding DNA during cloning or transformation (while still encoding an insecticidal protein).

Of course, an insect-resistant transgenic plant, as used herein, also includes any plant comprising a combination of genes encoding the proteins of any one of the above classes 1 to 10. In one embodiment, an insect-resistant plant contains more than one transgene encoding a protein of any one of the above classes 1 to 10, to expand the range of target insect species affected when using different proteins directed at different target insect species, or to delay insect resistance development to the plants by using different proteins insecticidal to the same target insect species but having a different mode of action, such as binding to different receptor binding sites in the insect.

An “insect-resistant transgenic plant”, as used herein, further includes any plant containing at least one transgene comprising a sequence producing upon expression a double-stranded RNA which upon ingestion by a plant insect pest inhibits the growth of this insect pest, as described for example in WO 2007/080126, WO 2006/129204, WO 2007/074405, WO 2007/080127 and WO 2007/035650.

Plants or plant cultivars (obtained by plant hiotechnoogy methods such as genetic engineering) which may also be treated according to the invention are tolerant to abiotic stresses. Such plants can be obtained by genetic transformation, or by selection of plants containing a mutation imparting such stress resistance. Particularly useful stress tolerance plants include:

• • 1) plants which contain a transgene capable of reducing the expression and/or the activity of the poly(ADP-ribose)polymerase (PARP) gene in the plant cells or plants as described in WO 00/04173, WO/2006/045633, EP 04077984.5 or EP 06009836.5;
  • 2) plants which contain a stress tolerance-enhancing transgene capable of reducing the expression and/or the activity of the PARC-encoding genes of the plants or plants cells, as described in e.g. WO 2004/090140;
  • 3) plants wTaien contain a stress tolerance-enhancing transgene encoding a plant-functional enzyme of the nicotinamide adenine dinucleotide salvage biosynthesis pathway including nicotinamidase, nicotinate phosphoribosyltransferase, nicotinic acid mononucleotide adenyl transferase, nicotinamide adenine dinucleotide synthetase or nicotine amide phosphoribosyltransferase as described e.g. in EP 04077624.7, WO 2006/133827, PCT/EP07/002433, EP 1999263 or WO 2007/107326.

Plants or plant cultivars (obtained by plant biotechnology methods such as genetic engineering) which may also be treated according to the invention show altered quantity, quality and/or storage qualities of the harvested product and/or altered properties of specific constituents of the harvested product, such as:

• • 1) transgenic plants which synthesize a modified starch, which in its physical-chemical characteristics, in particular the amylose content or the amyloselamylopectin ratio, the degree of branching, the average chain length, the side chain distribution, the viscosity behavior, the gelling strength, the starch grain size and/or the starch grain morphology, is changed in comparison with the synthesized starch in wild type plant cells or plants, so that this modified starch is better suited for special applications. Such transgenic plants synthesizing a modified starch are disclosed, for example in EP 0571427, WO 95/04826, EP 0719338, WO 96/15248, WO 96/19581, WO 96/27674, WO 97/11188, WO 97/26362, WO 97/32985, WO 97/42328, WO 97/44472, WO 97/45545, WO 98/27212, WO 98/40503, WO 99/58688, WO 99/58690, WO 99/58654, WO 00/08184, WO 00/08185, WO 00/08175, WO 00/28052, WO 00/77229, WO 01/12782, WO 01/12826, WO 02/101059, WO 03/071860, WO 2004/056999, WO 2005/030942, WO 2005/030941., WO 2005/095632, WO 2005/095617, WO 2005/095619, WO 2005/095618, WO 2005/123927, WO 2006/018319, WO 2006/103107, WO 2006/108702, WO 2007/009823, WO 00/22140, WO 2006/063862, WO 2006/072603, WO 02/034923, EP 06090134.5, EP 06090228.5, EP 06090227.7, EP 07090007.1, EP 07090009.7, WO 01/14569, WO 02/79410, WO 03/33540, WO 2004/078983, WO 01/19975, WO 95/26407, WO 96/34968, WO 98/20145, WO 99/12950, WO 99/66050, WO 99/53072, U.S. Pat. No. 6,734,341, WO 00/11192, WO 98/22604, WO 98/32326, WO 01/98509, WO 01/98509, WO 2005/002359, U.S. Pat. No. 5,824,790, U.S. Pat. No. 6,013,861, WO 94/04693, WO 94/09144, WO 94/11520, WO 95/35026 and WO 97/20936.

Transgenic plants which synthesize non-starch carbohydrate polymers or which synthesize non-starch carbohydrate polymers with altered properties in comparison to wild type plants without genetic modification. Example are plants producing polyfructose, especially of the inulin and levan type, as disclosed in EP 0663956, WO 96/01904, WO 96/21023, WO 98/39460 and WO 99/24593, plants producing alpha-1,4-glucans as disclosed in WO 95/31553, US 2002031826, U.S. Pat. No. 6,284,479, U.S. Pat. No. 5,712,107, WO 97/47806, WO 97/47807, WO 97/47808 and WO 00/14249, plants producing alpha-1,6 branched alpha-1,4-glucans, as disclosed in WO 00/73422, and plants producing alternan, as disclosed in WO 00/47727, WO 00/73422, EP 06077301.7, U.S. Pat. No. 5,908,975 and EP 0728213.

• • 3) Transgenic plants which produce hyaluronan, as for example disclosed in WO 2006/032538, WO 2007/039314, WO 2007/039315, WO 2007/039316, JP 2006304779 and WO 2005/012529.
  • 4) Transgenic plants or hybrid plants, such as onions with characteristics such as ‘high soluble solids content’, ‘low pungency’ (LP) and/or ‘long storage’ (LS), as described in U.S. patent application Ser. Nos. 12/020,360 and 61/054,026.

Plants or plant cultivars (that have been obtained by plant biotechnology methods such as genetic engineering) which may also be treated according to the invention are plants, such as cotton plants, with altered fiber characteristics. Such plants can be obtained by genetic transformation, or by selection of plants which contain a mutation imparting such altered fiber characteristics and include:

• • a) plants, such as cotton plants, containing an altered form of cellulose synthase genes as described in WO 98/00549,
  • b) plants, such as cotton plants, cont, containing an altered form of rsw2 or rsw3 homologous :nucleic acids as described in WO 2004/053219;
  • c) plants, such as cotton plants, with increased expression of sucrose phosphate synthase as described in WO 01/17333;
  • d) plants, such as cotton plants, with increased expression of sucrose synthase as described in WO 02/45485;
  • e) plants, such as cotton plants, wherein the timing of the plasmodesmatal gating at the basis of the fiber cell is altered, e.g. through downregulation of fiber-selective β-1,3-glucanase as described in WO 2005/017157, or as described in EP 08075514.3 or in U.S. patent application No. 61/128,938;
  • f) plants, such as cotton plants, having fibers with altered reactivity, e.g. through the expression of N-acetylglucosamintransferase gene including nodC and chitin synthase genes as described in WO 2006/136351.

Plants or plant cultivars (that have been obtained by plant biotechnology methods such as genetic engineering) which may also be treated according to the invention are plants, such as oilseed rape or related Brassica plants, with altered oil profile characteristics, Such plants can be obtained by genetic transformation, or by selection of plants which contain a mutation imparting such altered oil characteristics and include;

• • a) plants, such as oilseed rape plants, producing oil having a high oleic acid content as described e.g. in U.S. Pat. No. 5,969,169, U.S. Pat. No. 5,840,946 or U.S. Pat. No. 6,323,392 or U.S. Pat. No. 6,063, 947;
  • b) plants such as oilseed rape plants, producing oil having a low linolenic acid content as described in U.S. Pat. No. 6,270,828, U.S. Pat. No. 6,169,190 or U.S. Pat. No. 5,965,755.
  • c) Plants such as oilseed rape plants, producing oil having a low level of saturated fatty acids as described e.g. in U.S. Pat. No. 5,434,283 or U.S. patent application Ser. No. 12/668,303.

Plants or plant cultivars (that have been obtained by plant biotechnology methods such as genetic engineering) which may also be treated according to the invention are plants, such as oilseed rape or related Brassica plants, with altered seed shattering characteristics. Such plants can be obtained by genetic transformation, or by selection of plants which contain a mutation imparting such altered seed shattering characteristics and include plants such as oilseed rape plants with delayed or reduced seed shattering as described in U.S. patent application No. 61/135,230, WO09/068313 and WO10/006732.

Particularly useful transgenic plants which may be treated according to tare invention are plants containing transformation events, or combinations of transformation events, that are the subject of petitions for non-regulated status, in the United States of America, to the Animal and Plant Health Inspection Service (APHIS) of the United States Department of Agriculture (USDA), whether such petitions are granted or are still pending, At any time this information is readily available from APHIS (4700 River Road, Riverdale, Md. 20737, USA), for instance on its Internet site (URL http://www.aphis.usda.gov/brs/not_eg.html). On the filing date of this application the petitions for non-regulated status that were pending with APHIS or granted by APHIS were those listed in table B which contains the following information:

• • Petition: the identification number of the petition. Technical descriptions of the transformation events can he found in the individual petition documents wnich are obtainable from APHIS, for example on the APHIS website, byr reference to this petition number. These descriptions are herein incorporated by reference,
  • Extension of a peri n: reference to a previous petition for which an extension is requested.
  • Institution: the name of the entity submitting the petition.
  • Regulated article: the plant species concerned.
  • Transgenic phenotype: the trait conferred to the plants by the transfo. ation event,
  • Transformation event or line: the name of the event or events (sometimes also designated as line or lines) for which non-regulated status is requested,
  • APHIS documents: various documents published by APHIS in relation to the petition and which can be requested from APHIS.

Additionally particularly useful plants containing single transformation events or a combination of transformation events are listed for example in the database from various national or regional regulatory agencies (see for example http://gmoinfojrc.itigmp_browse,aspx and http://cera-gmc.org/index.php?evidcode=&hstIDXCode=&gType=&AbbrCode=&atCode=&stCode=&coIDCode=&action=gm_crop_database&mode=Submit).

Further particular transgenic plants include plants containinga transgene in an agronomically neutral or beneficial position as described in any of the patent publications listed in table C.

In one embodiment of the invention the plants A-1 to A-183 of table A, in total or in part, or propagation material of said plants, is treated or contacted with the active ingredient combinations of the invention, alone or in the form of compositions coin ising an active ingredient combination.

	Transgenic
No.	event	Company	Description	Crop
A-1	ASR368	Scotts Seeds	Glyphosate tolerance derived by inserting a modified 5-	Agrostis
			enolpyruvylshikimate-3-phosphate synthase (EPSPS)	stolonifera
			encoding gene from Agrobacterium tumefaciens, parent	Creeping
			line B99061.	bentgrass
A-2	Asr-368		Glyphosate tolerance; US 2006-162007	bentgrass
A-3	H7-1	Monsanto	Glyphosate herbicide tolerant sugar beet produced by	Beta vulgaris
		Company	inserting a gene encoding the enzyme 5-
			enolypyruvylshikimate-3-phosphate synthase (EPSPS)
			from the CP4 strain of Agrobacterium tumefaciens;
			WO 2004-074492
A-4	T120-7	Bayer Crop-	Introduction of the PPT-acetyltransferase (PAT)	Beta vulgaris
		Science	encoding gene from Streptomyces viridochromogenes,
		(Aventis Crop-	an aerobic soil bacterium. PPT normally acts to inhibit
		Science	glutamine synthetase, causing a fatal accumulation of
		(AgrEvo))	ammonia. Acetylated PPT is inactive.
A-5	GTSB77	Novartis Seeds;	Glyphosate herbicide tolerant sugar beet produced by	Beta vulgaris
		Monsanto	inserting a gene encoding the enzyme 5-	(sugar beet)
		Company	enolypyruvylshikimate-3-phosphate synthase (EPSPS)
			from the CP4 strain of Agrobacterium tumefaciens.
A-6	T227-1		Glyphosate tolerance; US 2004-117870	Beta vulgaris
				sugar beet
A-7	23-18-17, 23-	Monsanto	High laurate acid (12:0) and myristate acid (14:0) canola	Brassica
	198	Company	produced by inserting a thioesterase encoding gene from	napus
		(formerly	the California bay laurel (Umbellularia californica).	(Argentine
		Calgene)		Canola)
A-8	45A37, 46A40	Pioneer Hi-Bred	High oleic acid and low linolenic acid canola produced	Brassica
		International	through a combination of chemical mutagenesis to select	napus
		Inc.	for a fatty acid desaturase mutant with elevated oleic	(Argentine
			acid content, and traditional back-crossing to introduce	Canola)
			the low linolenic acid trait.
A-9	46A12, 46A16	Pioneer Hi-Bred	Combination of chemical mutagenesis, to achieve the	Brassica
		International	high oleic acid trait, and traditional breeding with	napus
		Inc.	registered canola varieties.	(Argentine
				Canola)
A-10	GT200	Monsanto	Glyphosate herbicide tolerant canola produced by	Brassica
		Company	inserting genes encoding the enzymes 5-	napus
			enolypyruvylshikimate-3-phosphate synthase (EPSPS)	(Argentine
			from the CP4 strain of Agrobacterium tumefaciens and	Canola)
			glyphosate oxidase from Ochrobactrum anthropi.
A-11	GT73, RT73	Monsanto	Glyphosate herbicide tolerant canola produced by	Brassica
		Company	inserting genes encoding the enzymes 5-	napus
			enolypyruvylshikimate-3-phosphate synthase (EPSPS)	(Argentine
			from the CP4 strain of Agrobacterium tumefaciens and	Canola)
			glyphosate oxidase from Ochrobactrum anthropi.
A-12	HCN10	Aventis	Introduction of the PPT-acetyltransferase (PAT)	Brassica
		CropScience	encoding gene from Streptomyces viridochromogenes,	napus
			an aerobic soil bacterium. PPT normally acts to inhibit	(Argentine
			glutamine synthetase, causing a fatal accumulation of	Canola)
			ammonia. Acetylated PPT is inactive.
A-13	HCN92	Bayer Crop-	Introduction of the PPT-acetyltransferase (PAT)	Brassica
		Science	encoding gene from Streptomyces viridochromogenes,	napus
		(Aventis Crop-	an aerobic soil bacterium. PPT normally acts to inhibit	(Argentine
		Science	glutamine synthetase, causing a fatal accumulation of	Canola)
		(AgrEvo))	ammonia. Acetylated PPT is inactive.
A-14	MS1, RF1 =>	Aventis	Male sterility, fertility restoration, pollination control	Brassica
	PGS1	CropScience	system displaying glufosinate herbicide tolerance. MS	napus
		(formerly Plant	lines contained the barnase gene from Bacillus	(Argentine
		Genetic	amyloliquefaciens, RF lines contained the barstar gene	Canola)
		Systems)	from the same bacterium, and both lines contained the
			phosphinothricin N-acetyltransferase (PAT) encoding
			gene from Streptomyces hygroscopicus.
A-15	MS1, RF2 =>	Aventis	Male sterility, fertility restoration, pollination control	Brassica
	PGS2	CropScience	system displaying glufosinate herbicide tolerance. MS	napus
		(formerly Plant	lines contained the barnase gene from Bacillus	(Argentine
		Genetic	amyloliquefaciens, RF lines contained the barstar gene	Canola)
		Systems)	from the same bacterium, and both lines contained the
			phosphinothricin N-acetyltransferase (PAT) encoding
			gene from Streptomyces hygroscopicus.
A-16	MS8 × RF3	Bayer	Male sterility, fertility restoration, pollination control	Brassica
		CropScience	system displaying glufosinate herbicide tolerance. MS	napus
		(Aventis	lines contained the barnase gene from Bacillus	(Argentine
		CropScience	amyloliquefaciens, RF lines contained the barstar gene	Canola)
		(AgrEvo))	from the same bacterium, and both lines contained the
			phosphinothricin N-acetyltransferase (PAT) encoding
			gene from Streptomyces hygroscopicus.
A-17	MS-B2		Male sterility, WO 01/31042	Brassica
				napus
				(Argentine
				Canola)
A-18	MS-BN1/RF-		Male sterility/restoration; WO 01/41558	Brassica
	BN1			napus
				(Argentine
				Canola)
A-19	NS738,	Pioneer Hi-Bred	Selection of somaclonal variants with altered	Brassica
	NS1471,	International	acetolactate synthase (ALS) enzymes, following	napus
	NS1473	Inc.	chemical mutagenesis. Two lines (P1, P2) were initially	(Argentine
			selected with modifications at different unlinked loci.	Canola)
			NS738 contains the P2 mutation only.
A-20	OXY-235	Aventis	Tolerance to the herbicides bromoxynil and ioxynil by	Brassica
		CropScience	incorporation of the nitrilase gene from Klebsiella	napus
		(formerly Rhône	pneumoniae.	(Argentine
		Poulenc Inc.)		Canola)
A-21	PHY14,	Aventis	Male sterility was obtained via insertion of the barnase	Brassica
	PHY35	CropScience	ribonuclease gene from Bacillus amyloliquefaciens;	napus
		(formerly Plant	fertility restoration by insertion of the barstar RNase	(Argentine
		Genetic	inhibitor; PPT resistance via PPT-acetyltransferase	Canola)
		Systems)	(PAT) from Streptomyces hygroscopicus.
A-22	PHY36	Aventis	Male sterility was obtained via insertion of the barnase	Brassica
		CropScience	ribonuclease gene from Bacillus amyloliquefaciens;	napus
		(formerly Plant	fertility restoration by insertion of the barstar RNase	(Argentine
		Genetic	inhibitor; PPT-acetyltransferase (PAT) from	Canola)
		Systems)	Streptomyces hygroscopicus.
A-23	RT73		Glyphosate resistance; WO 02/36831	Brassica
				napus
				(Argentine
				Canola)
A-24	T45 (HCN28)	Bayer Crop-	Introduction of the PPT-acetyltransferase (PAT)	Brassica
		Science	encoding gene from Streptomyces viridochromogenes,	napus
		(Aventis	an aerobic soil bacterium. PPT normally acts to inhibit	(Argentine
		CropScience	glutamine synthetase, causing a fatal accumulation of	Canola)
		(AgrEvo))	ammonia. Acetylated PPT is inactive.
A-25	HCR-1	Bayer Crop	Introduction of the glufosinate ammonium herbicide	Brassica
		Science	tolerance trait from transgenic B. napus line T45. This	rapa
		(Aventis	trait is imparted by the gene for phosphinothricin	(Polish
		CropScience	acetyltransferase (PAT) from S. viridochromogenes.	Canola)
		(AgrEvo))
A-26	ZSR500/502	Monsanto	Introduction of a modified 5-enol-pyruvylshikimate-3-	Brassica
		Company	phosphate synthase (EPSPS) and a gene from	rapa
			Achromobacter sp., that degrades glyphosate by	(Polish
			conversion to aminomethylphosphonic acid (AMPA)	Canola)
			and glyoxylate by interspecific crossing with GT73.
A-27	EE-1		Insect resistance (Cry1Ac); WO 2007/091277	aubergine
A-28	55-1/63-1	Cornell	Papaya ringspot virus (PRSV)-resistant papaya produced	Carica
		University	by inserting the coat protein (CP)-encoding sequences	papaya
			from this plant potyvirus.	(papaya)
A-29	RM3-3, RM3-	Bejo Zaden BV	Male sterility was obtained via insertion of the barnase	Cichorium
	4, RMS-6		ribonuclease gene from Bacillus amyloliquefaciens; PPT	intybus
			resistance was obtained via the bar gene from	(chicory)
			S. hygroscopicus, which encodes the PAT enzyme.
A-30	A, B	Agritope Inc.	Reduced accumulation of S-adenosylmethionine (SAM),	Cucumis
			and consequently reduced ethylene synthesis, by	melo
			introduction of the gene encoding S-adenosylmethionine	(melon)
			hydrolase.
A-31	CZW-3	Asgrow (USA);	Cucumber mosaic virus (CMV)-, zucchini yellows	Cucurbita
		Seminis	mosaic virus (ZYMV)- and watermelon mosaic virus	pepo
		Vegetable Inc.	(WMV) 2-resistant squash (Curcurbita pepo) produced	(squash)
		(Canada)	by inserting the coat protein (CP)-encoding sequences
			from each of these plant viruses into the host genome.
A-32	ZW20	Upjohn (USA);	Zucchini yellows mosaic (ZYMV)- and watermelon	Cucurbita
		Seminis	mosaic virus (WMV) 2-resistant squash (Curcurbita	pepo
		Vegetable Inc.	pepo) produced by inserting the coat protein	(squash)
		(Canada)	(CP)-encoding sequences from each of these plant
			potyviruses into the host genome.
A-33	66	Florigene Pty	Delayed senescence and sulfonylurea herbicide-tolerant	Dianthus
		Ltd.	carnations produced by inserting a truncated copy of the	caryophyllus
			carnation aminocyclopropane cyclase (ACC) synthase	(carnation)
			encoding gene in order to suppress expression of the
			endogenous unmodified gene, which is required for
			normal ethylene biosynthesis. Tolerance to sulfonylurea
			herbicides was obtained via the introduction of a
			chlorosulfuron-tolerant version of the acetolactate
			synthase (ALS)-encoding gene from tobacco.
A-34	4, 11, 15, 16	Florigene Pty	Modified color and sulfonylurea herbicide-tolerant	Dianthus
		Ltd.	carnations produced by inserting two anthocyanin	caryophyllus
			biosynthetic genes whose expression results in a	(carnation)
			violet/mauve coloration. Tolerance to sulfonylurea
			herbicides was obtained via the introduction of a
			chlorosulfuron-tolerant version of the acetolactate
			synthase (ALS)-encoding gene from tobacco.
A-35	959A, 988A,	Florigene Pty	Introduction of two anthocyanin biosynthetic genes	Dianthus
	1226A, 1351A,	Ltd.	which results in a violet/mauve coloration; introduction	caryophyllus
	1363A, 1400A		of a variant form of acetolactate synthase (ALS).	(carnation)
A-36	3560.4.3.5		Glyphosate/ALS inhibitor-tolerance; WO 2008002872	Glycine max
				L. (soya
				bean)
A-37	A2704-12		Glufosinate tolerance; WO 2006/108674	Glycine max
				L. (soya
				bean)
A-38	A2704-12,	Aventis	Glufosinate ammonium herbicide-tolerant soya bean	Glycine max
	A2704-21,	CropScience	produced by inserting a modified phosphinothricin	L. (soya
	A5547-35		acetyltransferase (PAT)-encoding gene from the soil	bean)
			bacterium Streptomyces viridochromogenes.
A-39	A5547-127	Bayer	Glufosinate ammonium herbicide-tolerant soya bean	Glycine max
		CropScience	produced by inserting a modified phosphinothricin	L. (soya
		(Aventis	acetyltransferase (PAT)-encoding gene from the soil	bean)
		CropScience	bacterium Streptomyces viridochromogenes.
		(AgrEvo))
A-40	A5547-35		Glufosinate tolerance; WO 2006/108675	Glycine max
				L. (soya
				bean)
A-41	DP-305423-1		High oleic acid content/ALS inhibitor tolerance;	Glycine max
			WO 2008/054747	L. (soya
				bean)
A-42	DP356043	Pioneer Hi-Bred	Soya bean event with two herbicide tolerance genes:	Glycine max
		International	glyphosate N-acetyltransferase, which detoxifies	L. (soya
		Inc.	glyphosate, and a modified acetolactate synthase (A	bean)
A-43	G94-1, G94-	DuPont Canada	High oleic acid soya bean produced by inserting a	Glycine max
	19, G168	Agricultural	second copy of the fatty acid desaturase (GmFad2-1)	L. (soya
		Products	encoding gene from soya bean, which resulted in	bean)
			“silencing” of the endogenous host gene.
A-44	GTS 40-3-2	Monsanto	Glyphosate-tolerant soya bean variety produced by	Glycine max
		Company	inserting a modified 5-enolpyruvylshikimate-3-	L. (soya
			phosphate synthase (EPSPS)-encoding gene from the	bean)
			soil bacterium Agrobacterium tumefaciens.
A-45	GU262	Bayer	Glufosinate ammonium herbicide-tolerant soya bean	Glycine max
		CropScience	produced by inserting a modified phosphinothricin	L. (soya
		(Aventis	acetyltransferase (PAT)-encoding gene from the soil	bean)
		CropScience	bacterium Streptomyces viridochromogenes.
		(AgrEvo))
A-46	MON87701		Insect resistance (Cry1Ac); WO 2009064652	Glycine max
				L. (soya
				bean)
A-47	MON87705		altered fatty acid levels (mid-oleic acid and low	Glycine max
			saturated); WO 2010037016	L. (soya
				bean)
A-48	MON87754		Increased oil content; WO 2010024976	Glycine max
				L. (soya
				bean)
A-49	MON87769		Stearidonic acid (SDA)-comprising oil;	Glycine max
			WO 2009102873	L. (soya
				bean)
A-50	MON89788	Monsanto	Glyphosate-tolerant soya bean variety produced by	Glycine max
		Company	inserting a modified 5-enolpyruvylshikimate-3-	L. (soya
			phosphate synthase (EPSPS)-encoding aroA (epsps)	bean)
			gene from Agrobacterium tumefaciens CP4;
			WO 2006130436
A-51	OT96-15	Agriculture &	Low linolenic acid soya bean produced through	Glycine max
		Agri-Food	traditional cross-breeding to incorporate the novel trait	L. (soya
		Canada	from a naturally occurring fan1 gene mutant that was	bean)
			selected for low linolenic acid content.
A-52	W62, W98	Bayer	Glufosinate ammonium herbicide-tolerant soya bean	Glycine max
		CropScience	produced by inserting a modified phosphinothricin	L. (soya
		(Aventis	acetyltransferase (PAT)-encoding gene from the soil	bean)
		CropScience	bacterium Streptomyces hygroscopicus.
		(AgrEvo))
A-53	15985	Monsanto	Insect-resistant cotton derived by transformation of the	Gossypium
		Company	DP50B parent variety, which contained event 531	hirsutum L.
			(expressing Cry1Ac protein), with purified plasmid	(cotton)
			DNA containing the cry2Ab- gene from B. thuringiensis
			subsp. kurstaki.
A-54	1143-14A		Insect resistance (Cry1Ab); WO 2006/128569	Gossypium
				hirsutum L.
				(cotton)
A-55	1143-51B		Insect resistance (Cry1Ab); WO 2006/128570	Gossypium
				hirsutum L.
				(cotton)
A-56	19-51A	DuPont Canada	Introduction of a variant form of acetolactate synthase	Gossypium
		Agricultural	(ALS).	hirsutum L.
		Products		(cotton)
A-57	281-24-236	DOW	Insect-resistant cotton produced by inserting the cry1F	Gossypium
		AgroSciences	gene from Bacillus thuringiensisvar. aizawai. The	hirsutum L.
		LLC	PAT-encoding gene from Streptomyces	(cotton)
			viridochromogenes was introduced as a selectable
			marker.
A-58	3006-210-23	DOW	Insect-resistant cotton produced by inserting the cry1Ac	Gossypium
		AgroSciences	gene from Bacillus thuringiensissubsp. kurstaki. The	hirsutum L.
		LLC	PAT-encoding gene from Streptomyces	(cotton)
			viridochromogenes was introduced as a selectable
			marker.
A-59	31807/31808	Calgene Inc.	Insect-resistant bromoxynil herbicide-tolerant cotton	Gossypium
			produced by inserting the cry1Ac gene from Bacillus	hirsutum L.
			thuringiensis and a nitrilase-encoding gene from	(cotton)
			Klebsiella pneumoniae.
A-60	BXN	Calgene Inc.	Bromoxynil herbicide-tolerant cotton produced by	Gossypium
			inserting a nitrilase-encoding gene from Klebsiella	hirsutum L.
			pneumoniae.	(cotton)
A-61	CE43-67B		Insect resistance (Cry1Ab); WO 2006/128573	Gossypium
				hirsutum L.
				(cotton)
A-62	CE44-69D		Insect resistance (Cry1Ab); WO 2006/128571	Gossypium
				hirsutum L.
				(cotton)
A-63	CE46-02A		Insect resistance (Cry1Ab); WO 2006/128572	Gossypium
				hirsutum L.
				(cotton)
A-64	Cot102		Insect resistance (Vip3A); US 2006-130175	Gossypium
				hirsutum L.
				(cotton)
A-65	COT102	Syngenta Seeds,	Insect-resistant cotton produced by inserting the	Gossypium
		Inc.	vip3A(a) gene from Bacillus thuringiensis AB88. The	hirsutum L.
			APH4-encoding gene from E. coli was introduced as a	(cotton)
			selectable marker.
A-66	COT202		Insect resistance (VIP3A); US2009181399	Gossypium
				hirsutum L.
				(cotton)
A-67	Cot202		Insect resistance (VIP3); US 2007-067868	Gossypium
				hirsutum L.
				(cotton)
A-68	DAS-21Ø23-5 ×	DOW	WideStrike ™, a stacked insect-resistant cotton derived	Gossypium
	DAS-24236-5	AgroSciences	from conventional cross-breeding of parental lines 3006-	hirsutum L.
		LLC	210-23 (OECD identifier: DAS-21Ø23-5) and 281-24-	(cotton)
			236 (OECD identifier: DAS-24236-5).
A-69	DAS-21Ø23-5 ×	DOW	Stacked insect-resistant and glyphosate-tolerant cotton	Gossypium
	DAS-24236-5 ×	AgroSciences	derived from conventional cross-breeding of WideStrike	hirsutum L.
	MON88913	LLC und	cotton (OECD identifier: DAS-21Ø23-5 × DAS-24236-	(cotton)
		Pioneer Hi-Bred	5) with MON88913, known as RoundupReady Flex
		International	(OECD identifier: MON-88913-8).
		Inc.
A-70	DAS-21Ø23-5 ×	DOW	WideStrike ™/Roundup Ready ® cotton, a stacked	Gossypium
	DAS-24236-5 ×	AgroSciences	insect-resistant and glyphosate-tolerant cotton derived	hirsutum L.
	MON-Ø1445-2	LLC	from conventional cross-breeding of WideStrike cotton	(cotton)
			(OECD identifier: DAS-21Ø23-5 × DAS-24236-5) with
			MON1445 (OECD identifier: MON-Ø1445-2).
A-71	EE-GH3		Glyphosate tolerance; WO 2007/017186	Gossypium
				hirsutum L.
				(cotton)
A-72	EE-GH5		Insect resistance (Cry1Ab); WO 2008/122406	Gossypium
				hirsutum L.
				(cotton)
A-73	EE-GH6		Insect resistance (cry2Ae); WO2008151780	Gossypium
				hirsutum L.
				(cotton)
A-74	event 281-24-		Insect resistance (Cry1F); WO 2005/103266	Gossypium
	236			hirsutum L.
				(cotton)
A-75	event3006-		Insect resistance (Cry1Ac); WO 2005/103266	Gossypium
	210-23			hirsutum L.
				(cotton)
A-76	GBH614	Bayer	Glyphosate herbicide-tolerant cotton produced by	Gossypium
		CropScience	inserting the 2MEPSPS gene into variety Coker312 by	hirsutum L.
		(Aventis	Agrobacterium under the control of Ph4a748At and	(cotton)
		CropScience	TpotpC.
		(AgrEvo))
A-77	LLCotton25	Bayer	Glufosinate ammonium herbicide-tolerant cotton	Gossypium
		CropScience	produced by inserting a modified phosphinothricin	hirsutum L.
		(Aventis	acetyltransferase (PAT)-encoding gene from the soil	(cotton)
		CropScience	bacterium Streptomyces hygroscopicus;
		(AgrEvo))	WO 2003013224
A-78	LLCotton25 ×	Bayer	Stacked herbicide-tolerant and insect-resistant cotton	Gossypium
	MON15985	CropScience	combining tolerance to glufosinate ammonium herbicide	hirsutum L.
		(Aventis	from LLCotton25 (OECD identifier: ACS-GHØØ1-3)	(cotton)
		CropScience	with resistance to insects from MON15985 (OECD
		(AgrEvo))	identifier: MON-15985-7).
A-79	MON 15985		Insect resistance (Cry1A/Cry2Ab); US 2004-250317	Gossypium
				hirsutum L.
				(cotton)
A-80	MON1445/1698	Monsanto	Glyphosate herbicide-tolerant cotton produced by	Gossypium
		Company	inserting a naturally glyphosate-tolerant form of the	hirsutum L.
			enzyme 5-enolpyruvylshikimate-3-phosphate synthase	(cotton)
			(EPSPS) from the CP4 strain of A. tumefaciens.
A-81	MON15985 ×	Monsanto	Stacked insect-resistant and glyphosate-tolerant cotton	Gossypium
	MON88913	Company	produced by conventional cross-breeding of the parental	hirsutum L.
			lines MON88913 (OECD identifier: MON-88913-8) and	(cotton)
			15985 (OECD identifier: MON-15985-7). Glyphosate
			tolerance is derived from line MON88913 which
			contains two genes encoding the enzyme 5-
			enolypyruvylshikimate-3-phosphate synthase (EPSPS)
			from the CP4 strain of Agrobacterium tumefaciens.
			Insect resistance is derived from the line MON15985
			which was produced by transformation of the DP50B
			parent variety, which contained event 531 (expressing
			the Cry1Ac protein), with purified plasmid DNA
			containing the cry2Ab gene from B. thuringiensis subsp.
			kurstaki.
A-82	MON-15985-7 ×	Monsanto	Stacked insect-resistant and herbicide-tolerant cotton	Gossypium
	MON-Ø1445-2	Company	derived from conventional cross-breeding of the parental	hirsutum L.
			lines 15985 (OECD identifier: MON-15985-7) and	(cotton)
			MON-1445 (OECD identifier: MON-Ø1445-2).
A-83	MON531/757/	Monsanto	Insect-resistant cotton produced by inserting the cry1Ac	Gossypium
	1076	Company	gene from Bacillus thuringiensis subsp. kurstaki HD-73	hirsutum L.
			(B.t.k.).	(cotton)
A-84	MON88913	Monsanto	Glyphosate herbicide-tolerant cotton produced by	Gossypium
		Company	inserting two genes encoding the enzyme 5-	hirsutum L.
			enolypyruvylshikimate-3-phosphate synthase (EPSPS)	(cotton)
			from the CP4 strain of Agrobacterium tumefaciens; WO
			2004/072235
A-85	MON-ØØ531-	Monsanto	Stacked insect-resistant and herbicide-tolerant cotton	Gossypium
	6 × MON-	Company	derived from conventional cross-breeding of the parental	hirsutum L.
	Ø1445-2		lines MON531 (OECD identifier: MON-ØØ531-6) and	(cotton)
			MON-1445 (OECD identifier: MON-Ø1445-2).
A-86	PV-GHGT07		Glyphosate tolerance; US 2004-148666	Gossypium
	(1445)			hirsutum L.
				(cotton)
A-87	T304-40		Insect resistance (Cry1Ab); WO2008/122406	Gossypium
				hirsutum L.
				(cotton)
A-88	T342-142		Insect resistance (Cry1Ab); WO 2006/128568	Gossypium
				hirsutum L.
				(cotton)
A-89	X81359	BASF Inc.	Tolerance to imidazolinone herbicides by selection of a	Helianthus
			naturally occurring mutant.	annuus
				(sunflower)
A-90	RH44	BASF Inc.	Selection for a mutagenized version of the enzyme	Lens
			acetohydroxy acid synthase (AHAS), also known as	culinaris
			acetolactate synthase (ALS) or acetolactate pyruvate	(lentil)
			lyase.
A-91	FP967	University of	A variant form of acetolactate synthase (ALS) was	Linum
		Saskatchewan,	obtained from a chlorosulfuron-tolerant line of	usitatissimum
		Crop Dev.	A. thaliana and used to transform flax.	L. (flax,
		Centre		linseed)
A-92	5345	Monsanto	Resistance to lepidopteran pests through the introduction	Lycopersicon
		Company	of the cry1Ac gene from Bacillus thuringiensis subsp.	esculentum
			kurstaki.	(tomato)
A-93	8338	Monsanto	Introduction of a gene sequence encoding the enzyme 1-	Lycopersicon
		Company	aminocyclopropane-1-carboxylic acid deaminase	esculentum
			(ACCd) that metabolizes the precursor of the fruit	(tomato)
			ripening hormone ethylene.
A-94	1345-4	DNA Plant	Delayed ripening tomatoes produced by inserting an	Lycopersicon
		Technology	additional copy of a truncated, gene encoding 1-	esculentum
		Corporation	aminocyclopropane-1-carboxylic acid (ACC) synthase,	(tomato)
			which resulted in downregulation of the endogenous
			ACC synthase and reduced ethylene accumulation.
A-95	35 1 N	Agritope Inc.	Introduction of a gene sequence encoding the enzyme S-	Lycopersicon
			adenosylmethionine hydrolase that metabolizes the	esculentum
			precursor of the fruit ripening hormone ethylene.	(tomato)
A-96	B, Da, F	Zeneca Seeds	Delayed softening tomatoes produced by inserting a	Lycopersicon
			truncated version of the polygalacturonase	esculentum
			(PG)-encoding gene in the sense or anti-sense	(tomato)
			orientation in order to reduce expression of the
			endogenous PG gene, and thus reduce pectin
			degradation.
A-97	FLAVR SAVR	Calgene Inc.	Delayed softening tomatoes produced by inserting an	Lycopersicon
			additional copy of the polygalacturonase (PG)-encoding	esculentum
			gene in the anti-sense orientation in order to reduce	(tomato)
			expression of the endogenous PG gene and thus reduce
			pectin degradation.
A-98	J101, J163	Monsanto	Glyphosate herbicide-tolerant alfalfa (Lucerne) produced	Medicago
		Company und	by inserting a gene encoding the enzyme 5-	sativa
		Forage Genetics	enolypyruvylshikimate-3-phosphate synthase (EPSPS)	(alfalfa)
		International	from the CP4 strain of Agrobacterium tumefaciens.
A-99	C/F/93/08-02	Societe National	Tolerance to the herbicides bromoxynil and ioxynil by	Nicotiana
		d'Exploitation	incorporation of the nitrilase gene from Klebsiella	tabacum L.
		des Tabacs et	pneumoniae.	(tobacco)
		Allumettes
A-100	Vector 21-41	Vector Tobacco	Reduced nicotine content through introduction of a	Nicotiana
		Inc.	second copy of the tobacco quinolinic acid	tabacum L.
			phosphoribosyltransferase (QTPase) in the antisense	(tobacco)
			orientation. The NPTII-encoding gene from E. coli was
			introduced as a selectable marker to identify
			transformants.
A-101	CL121,	BASF Inc.	Tolerance to the imidazolinone herbicide imazethapyr,	Oryza sativa
	CL141,		induced by chemical mutagenesis of the acetolactate	(rice)
	CFX51		synthase (ALS) enzyme using ethyl methanesulfonate (EMS).
A-102	GAT-OS2		Glufosinate tolerance; WO 01/83818	Oryza sativa
				(rice)
A-103	GAT-OS3		Glufosinate tolerance; US 2008-289060	Oryza sativa
				(rice)
A-104	IMINTA-1,	BASF Inc.	Tolerance to imidazolinone herbicides induced by	Oryza sativa
	IMINTA-4		chemical mutagenesis of the acetolactate synthase (ALS)	(rice)
			enzyme using sodium azide.
A-105	LLRICE06,	Aventis	Glufosinate ammonium herbicide-tolerant rice produced	Oryza sativa
	LLRICE62	CropScience	by inserting a modified phosphinothricin	(rice)
			acetyltransferase (PAT)-encoding gene from the soil
			bacterium Streptomyces hygroscopicus.
A-106	LLRICE601	Bayer Crop-	Glufosinate ammonium herbicide-tolerant rice produced	Oryza sativa
		Science	by inserting a modified phosphinothricin	(rice)
		(Aventis	acetyltransferase (PAT)-encoding gene from the soil
		CropScience	bacterium Streptomyces hygroscopicus.
		(AgrEvo))
A-107	PE-7		Insect resistance (Cry1Ac); WO 2008/114282	Oryza sativa
				(rice)
A-108	PWC16	BASF Inc.	Tolerance to the imidazolinon herbicide imazethapyr,	Oryza sativa
			induced by chemical mutagenesis of the acetolactate	(rice)
			synthase (ALS) enzyme using ethyl methanesulfonate
			(EMS).
A-109	TT51		Insect resistance (Cry1Ab/Cry1Ac); CN1840655	Oryza sativa
				(rice)
A-110	C5	United States	Plum pox virus (PPV)-resistant plum tree produced	Prunus
		Department of	through Agrobacterium-mediated transformation with a	domestica
		Agriculture -	coat protein (CP) gene from the virus.	(plum)
		Agricultural
		Research
		Service
	EH92-527	BASF Plant	Crop composition; Amflora; Unique EU identifier: BPS-25271-9
		Science
A-111	ATBT04-6,	Monsanto	Colorado potato beetle-resistant potatoes produced by	Solanum
	ATBT04-27,	Company	inserting the cry3A gene from Bacillus thuringiensis	tuberosum
	ATBT04-30,		(subsp. tenebrionis).	L. (potato)
	ATBT04-31,
	ATBT04-36,
	SPBT02-5,
	SPBT02-7
A-112	BT6, BT10,	Monsanto	Colorado potato beetle-resistant potatoes produced by	Solanum
	BT12, BT16,	Company	inserting the cry3A gene from Bacillus thuringiensis	tuberosum
	BT17, BT18,		(subsp. tenebrionis).	L. (potato)
	BT23
A-113	RBMT15-101,	Monsanto	Colorado potato beetle- and potato Y-virus (PVY)-	Solanum
	SEMT15-02,	Company	resistant potatoes produced by inserting the cry3A gene	tuberosum
	SEMT15-15		from Bacillus thuringiensis (subsp. tenebrionis) and the	L. (potato)
			coat protein-encoding gene from PVY.
A-114	RBMT21-129,	Monsanto	Colorado potato beetle- and potato leaf roll virus	Solanum
	RBMT21-350,	Company	(PLRV)-resistant potatoes produced by inserting the	tuberosum
	RBMT22-082		cry3A gene from Bacillus thuringiensis (subsp.	L. (potato)
			tenebrionis) and the replicase-encoding gene from
			PLRV.
A-115	AP205CL	BASF Inc.	Selection for a mutagenized version of the enzyme	Triticum
			acetohydroxy acid synthase (AHAS), also known as	aestivum
			acetolactate synthase (ALS) or acetolactate pyruvate	(wheat)
			lyase.
A-116	AP602CL	BASF Inc.	Selection for a mutagenized version of the enzyme	Triticum
			acetohydroxy acid synthase (AHAS), also known as	aestivum
			acetolactate synthase (ALS) or acetolactate pyruvate	(wheat)
			lyase.
A-117	BW255-2,	BASF Inc.	Selection for a mutagenized version of the enzyme	Triticum
	BW238-3		acetohydroxy acid synthase (AHAS), also known as	aestivum
			acetolactate synthase (ALS) or acetolactate pyruvate	(wheat)
			lyase.
A-118	BW7	BASF Inc.	Tolerance to imidazolinone herbicides induced by	Triticum
			chemical mutagenesis of the acetohydroxy acid synthase	aestivum
			(AHAS) gene using sodium azide.	(wheat)
A-119	Event 1		Fusarium resistance (trichothecene 3-O-	Triticum
			cetyltransferase); CA 2561992	aestivum
				(wheat)
A-120	JOPLIN1		Disease (fungal) resistance (trichothecene 3-O-	Triticum
			acetyltransferase); US 2008064032	aestivum
				(wheat)
A-121	MON71800	Monsanto	Glyphosate-tolerant wheat variety produced by inserting	Triticum
		Company	a modified 5-enolpyruvylshikimate-3-phosphate	aestivum
			synthase (EPSPS)-encoding gene from the CP4 strain of	(wheat)
			the soil bacterium Agrobacterium tumefaciens.
A-122	SWP965001	Cyanamid Crop	Selection for a mutagenized version of the enzyme	Triticum
		Protection	acetohydroxy acid synthase (AHAS), also known as	aestivum
			acetolactate synthase (ALS) or acetolactate pyruvate	(wheat)
			lyase.
A-123	Teal 11A	BASF Inc.	Selection for a mutagenized version of the enzyme	Triticum
			acetohydroxy acid synthase (AHAS), also known as	aestivum
			acetolactate synthase (ALS) or acetolactate pyruvate	(wheat)
			lyase.
A-124	176	Syngenta Seeds,	Insect-resistant maize produced by inserting the cry1Ab	Zea mays
		Inc.	gene from Bacillus thuringiensis subsp. kurstaki. The	L. (maize)
			genetic modification affords resistance to attack by the
			European Corn Borer (ECB).
A-125	3272		Self-processing corn (alpha-amylase); US 2006-230473	Zea mays
				L. (maize)
A-126	3751IR	Pioneer Hi-Bred	Selection of somaclonal variants by culture of embryos	Zea mays
		International	on imidazolinone-containing media.	L. (maize)
		Inc.
A-127	676, 678, 680	Pioneer Hi-Bred	Male-sterile and glufosinate ammonium herbicide-	Zea mays
		International	tolerant maize produced by inserting genes encoding	L. (maize)
		Inc.	DNA adenine methylase and phosphinothricin
			acetyltransferase (PAT) from Escherichia coli and
			Streptomyces viridochromogenes.
A-128	ACS-ZMØØ3-	Bayer Crop-	Stacked insect-resistant and herbicide-tolerant maize	Zea mays
	2 × MON-	Science	hybrid derived from conventional cross-breeding of the	L. (maize)
	ØØ81Ø-6	(Aventis	parental lines T25 (OECD identifier: ACS-ZMØØ3-2)
		CropScience	and MON810 (OECD identifier: MON-ØØ81Ø-6).
		(AgrEvo))
A-129	B16		Glufosinate resistance; US 2003-126634	Zea mays
				L. (maize)
A-130	B16 (DLL25)	Dekalb Genetics	Glufosinate ammonium herbicide-tolerant maize	Zea mays
		Corporation	produced by inserting the gene encoding	L. (maize)
			phosphinothricin acetyltransferase (PAT) from
			Streptomyces hygroscopicus.
A-131	BT11	Syngenta Seeds,	Insect-resistant and herbicide-tolerant maize produced	Zea mays
	(X4334CBR,	Inc.	by inserting the cry1Ab gene from Bacillus thuringiensis	L. (maize)
	X4734CBR)		subsp. kurstaki, and the phosphinothricin N-
			acetyltransferase (PAT)-encoding gene from
			S. viridochromogenes.
A-132	BT11 ×	Syngenta Seeds,	Stacked insect-resistant and herbicide-tolerant maize	Zea mays
	MIR604	Inc.	produced by conventional cross-breeding of parental	L. (maize)
			lines BT11 (OECD unique identifier: SYN-BTØ11-1)
			and MIR604 (OECD unique identifier: SYN-IR6Ø5-5).
			Resistance to the European Corn Borer and tolerance to
			the herbicide glufosinate ammonium (Liberty) is derived
			from BT11, which contains the cry1Ab gene from
			Bacillus thuringiensis subsp. kurstaki, and the
			phosphinothricin N-acetyltransferase (PAT)-encoding
			gene from S. viridochromogenes. Corn rootworm-
			resistance is derived from MIR604 which contains the
			mcry3A-gene from Bacillus thuringiensis.
A-133	BT11 ×	Syngenta Seeds,	Stacked insect-resistant and herbicide-tolerant maize	Zea mays
	MIR604 ×	Inc.	produced by conventional cross-breeding of parental	L. (maize)
	GA21		lines BT11 (OECD unique identifier: SYN-BTØ11-1),
			MIR604 (OECD unique identifier: SYN-IR6Ø5-5) and
			GA21 (OECD unique identifier: MON- Ø Ø Ø21-9).
			Resistance to the European Corn Borer and tolerance to
			the herbicide glufosinate ammonium (Liberty) is derived
			from BT11, which contains the cry1Ab gene from
			Bacillus thuringiensis subsp. kurstaki, and the
			phosphinothricin N-acetyltransferase (PAT)-encoding
			gene from S. viridochromogenes. Corn rootworm-
			resistance is derived from MIR604 which contains the
			mcry3A gene from Bacillus thuringiensis. Tolerance to
			glyphosate herbicide is derived from GA21 which
			contains a modified EPSPS gene from maize.
A-134	CBH-351	Aventis	Insect-resistant and glufosinate ammonium herbicide-	Zea mays
		CropScience	tolerant maize developed by inserting the genes	L. (maize)
			encoding Cry9C protein from Bacillus thuringiensis
			subsp. tolworthi and phosphinothricin acetyltransferase
			(PAT) from Streptomyces hygroscopicus.
A-135	DAS-06275-8	DOW	Lepidopteran insect-resistant and glufosinate ammonium	Zea mays
		AgroSciences	herbicide-tolerant maize variety produced by inserting	L. (maize)
		LLC	the cry1F gene from Bacillus thuringiensis var. aizawai
			and the phosphinothricin acetyltransferase (PAT) from
			Streptomyces hygroscopicus.
A-136	DAS-59122-7	DOW	Corn rootworm-resistant maize produced by inserting	Zea mays
		AgroSciences	the cry34Ab1 and cry35Ab1 genes from the PS149B1	L. (maize)
		LLC and	strain of Bacillus thuringiensis. The PAT-encoding gene
		Pioneer Hi-Bred	from Streptomyces viridochromogenes was introduced
		International	as a selectable marker; US 2006-070139
		Inc.
A-137	DAS-59122-7 ×	DOW	Stacked insect-resistant and herbicide-tolerant maize	Zea mays
	NK603	AgroSciences	produced by conventional cross-breeding of parental	L. (maize)
		LLC and	lines DAS-59122-7 (OECD unique identifier: DAS-
		Pioneer Hi-Bred	59122-7) with NK603 (OECD unique identifier: MON-
		International	ØØ6Ø3-6). Corn rootworm-resistance is derived from
		Inc.	line DAS-59122-7 which contains the cry34Ab1 and
			cry35Ab1 genes from the PS149B1 strain of Bacillus
			thuringiensis. Tolerance to glyphosate herbicide is
			derived from NK603.
A-138	DAS-59122-7 ×	DOW	Stacked insect-resistant and herbicide-tolerant maize	Zea mays
	TC1507 ×	AgroSciences	produced by conventional cross-breeding of parental	L. (maize)
	NK603	LLC and	lines DAS-59122-7 (OECD unique identifier: DAS-
		Pioneer Hi-Bred	59122-7) and TC1507 (OECD unique identifier DAS-
		International	Ø15Ø7-1) with NK603 (OECD unique identifier: MON-
		Inc.	ØØ6Ø3-6). Corn rootworm-resistance is derived from
			line DAS-59122-7, which contains the cry34Ab1 and
			cry35Ab1 genes from the PS149B1 strain of Bacillus
			thuringiensis. Lepidopteran resistance and tolerance to
			glufosinate ammonium herbicide are derived from
			TC1507. Tolerance to glyphosate herbicide is derived
			from NK603.
A-139	DAS-Ø15Ø7-1 ×	DOW	Stacked insect-resistant and herbicide-tolerant maize	Zea mays
	MON-ØØ6Ø3-6	AgroSciences	derived from conventional cross-breeding of the parental	L. (maize)
		LLC	lines 1507 (OECD identifier: DAS-Ø15Ø7-1) and
			NK603 (OECD identifier: MON-ØØ6Ø3-6).
A-140	DBT418	Dekalb Genetics	Insect-resistant and glufosinate ammonium herbicide-	Zea mays
		Corporation	tolerant maize developed by inserting genes encoding	L. (maize)
			Cry1AC protein from Bacillus thuringiensis subsp
			kurstaki and phosphinothricin acetyltransferase (PAT)
			from Streptomyces hygroscopicus.
A-141	DK404SR	BASF Inc.	Somaclonal variants with a modified acetyl-CoA-	Zea mays
			carboxylase (ACCase) were selected by culture of	L. (maize)
			embryos on sethoxydim-enriched medium.
A-142	DP-098140-6		Glyphosate tolerance/ALS inhibitor tolerance;	Zea mays
			WO 2008/112019	L. (maize)
A-143	DP-Ø9814Ø-6	Pioneer Hi-Bred	Maize line 98140 was genetically engineered to express	Zea mays
	(Event 98140)	International	the GAT4621 (glyphosate acetyltransferase) and ZM-	L. (maize)
		Inc.	HRA (modified maize version of a acetolactate synthase)
			proteins. The GAT4621 protein, encoded by the gat4621
			gene, confers tolerance to glyphosate-containing
			herbicides by acetylating glyphosate and thereby
			rendering it non-phytotoxic. The ZM-HRA protein,
			encoded by the zm-hra gene, confers tolerance to the
			ALS-inhibiting class of herbicides.
A-144	Event 3272	Syngenta Seeds,	Maize line expressing a heat-stable alpha-amylase gene	Zea mays
		Inc.	amy797E for use in the dry-grind ethanol production	L. (maize)
			process. The phosphomannose isomerase gene from
			E. coli was used as a selectable marker.
A-145	EXP1910IT	Syngenta Seeds,	Tolerance to the imidazolinone herbicide imazethapyr,	Zea mays
		Inc. (formerly	induced by chemical mutagenesis of the acetolactate	L. (maize)
		Zeneca Seeds)	synthase (ALS) enzyme using ethyl methanesulfonate(EMS).
A-146	FI117		Glyphosate resistance; U.S. Pat. No. 6,040,497	Zea mays
				L. (maize)
A-147	GA21	Monsanto	Induction, by gene-gun bombardment, of a modified 5-	Zea mays
		Company	enolpyruvylshikimate-3-phosphate synthase (EPSPS), an	L. (maize)
			enzyme involved in the shikimate biosynthesis pathway
			for the production of the aromatic amino acids.
A-148	GAT-ZM1		Glufosinate tolerance; WO 01/51654	Zea mays
				L. (maize)
A-149	GG25		Glyphosate resistance; U.S. Pat. No. 6,040,497	Zea mays
				L. (maize)
A-150	GJ11		Glyphosate resistance; U.S. Pat. No. 6,040,497	Zea mays
				L. (maize)
A-151	IT	Pioneer Hi-Bred	Tolerance to the imidazolinone herbicide imazethapyr,	Zea mays
		International	was obtained by in vitro selection of somaclonal	L. (maize)
		Inc.	variants.
A-152	LY038	Monsanto	Altered amino acid composition, specifically elevated	Zea mays
		Company	levels of lysine, through the introduction of the cordapA	L. (maize)
			gene, derived from Corynebacterium glutamicum,
			encoding the enzyme dihydrodipicolinate synthase
			(cDHDPS); U.S. Pat. No. 7,157,281
A-153	MIR162		Insect resistance; WO 2007142840	Zea mays
				L. (maize)
A-154	MIR604	Syngenta Seeds,	Corn rootworm-resistant maize was produced by	Zea mays
		Inc.	transformation with a modified cry3A gene. The	L. (maize)
			phosphomannose isomerase gene from E. coli was used
			as a selectable marker; (Cry3a055); EP 1 737 290
A-155	MIR604 ×	Syngenta Seeds,	Stacked insect-resistant and herbicide-tolerant maize	Zea mays
	GA21	Inc.	produced by conventional cross-breeding of parental	L. (maize)
			lines MIR604 (OECD unique identifier: SYN-IR60Ø5-5)
			and GA21 (OECD unique identifier: MON- ØØØ21-9).
			Corn rootworm-resistance is derived from MIR604
			which contains the mcry3A gene from Bacillus
			thuringiensis. Tolerance to glyphosate herbicide is
			derived from GA21.
A-156	MON80100	Monsanto	Insect-resistant maize produced by inserting the cry1Ab	Zea mays
		Company	gene from Bacillus thuringiensis subsp. kurstaki. The	L. (maize)
			genetic modification affords resistance to attack by the
			European Corn Borer.
A-157	MON802	Monsanto	Insect-resistant and glyphosate herbicide-tolerant maize	Zea mays
		Company	produced by inserting the genes encoding the Cry1Ab	L. (maize)
			protein from Bacillus thuringiensis and the 5-
			enolpyruvylshikimate-3-posphate synthase (EPSPS)
			from the CP4 strain of A. tumefaciens.
A-158	MON809	Pioneer Hi-Bred	Resistance to European Corn Borer (Ostrinia nubilalis)	Zea mays
		International	by introduction of a synthetic cry1Ab gene. Glyphosate	L. (maize)
		Inc.	resistance via introduction of the bacterial version of a
			plant enzyme, 5-enolpyruvylshikimat-3-phosphate
			synthase (EPSPS).
A-159	MON810	Monsanto	Insect-resistant maize produced by inserting a truncated	Zea mays
		Company	form of the cry1Ab gene from Bacillus thuringiensis	L. (maize)
			subsp. kurstaki HD-1. The genetic modification affords
			resistance to attack by the European Corn Borer (ECB);
			US 2004-180373
A-160	MON810 ×	Monsanto	Stacked insect-resistant and glyphosate-tolerant maize	Zea mays
	MON88017	Company	derived from conventional cross-breeding of the parental	L. (maize)
			lines MON810 (OECD identifier: MON-ØØ81Ø-6) and
			MON88017 (OECD identifier: MON-88Ø17-3).
			European Corn Borer (ECB) resistance is derived from a
			truncated form of the cry1Ab gene from Bacillus
			thuringiensis subsp. kurstaki HD-1, present in MON810.
			Corn rootworm-resistance is derived from the cry3Bb1
			gene from the EG4691 strain of Bacillus thuringiensis
			subspecies kumamotoensis present in MON88017.
			Glyphosate tolerance is derived from a 5-
			enolpyruvylshikimate-3-phosphate synthase (EPSPS)-
			encoding gene from the CP4 strain of Agrobacterium
			tumefaciens present in MON88017.
A-161	MON832	Monsanto	Introduction, by gene-gun bombardment, of glyphosate	Zea mays
		Company	oxidase (GOX) and a modified 5-enolpyruvylshikimate-	L. (maize)
			3-phosphate synthase (EPSPS), an enzyme involved in
			the shikimate biosynthesis pathway for the production of
			the aromatic amino acids.
A-162	MON863	Monsanto	Corn rootworm-resistant maize produced by inserting	Zea mays
		Company	the cry3Bb1 gene from Bacillus thuringiensis subsp.	L. (maize)
			kumamotoensis.
A-163	MON87460		Drought tolerance; water deficit tolerance; WO	Zea mays
			2009/111263	L. (maize)
A-164	MON88017	Monsanto	Corn rootworm-resistant maize produced by inserting	Zea mays
		Company	the cry3Bb1 gene from the EG4691 strain of Bacillus	L. (maize)
			thuringiensis subsp. kumamotoensis. Glyphosate
			tolerance was derived by inserting a 5-
			enolpyruvylshikimate-3-phosphate synthase (EPSPS)-
			encoding gene from the CP4 strain of Agrobacterium
			tumefaciens; WO 2005059103
A-165	MON89034	Monsanto	Maize event expressing two different insecticidal	Zea mays
		Company	proteins from Bacillus thuringiensis providing resistance	L. (maize)
			to a number of lepidopteran pests; insect resistance
			(Lipidoptera-Cry1A.105-Cry2Ab); WO 2007140256
A-166	MON89034 ×	Monsanto	Stacked insect-resistant and glyphosate-tolerant maize	Zea mays
	MON88017	Company	derived from conventional cross-breeding of the parental	L. (maize)
			lines MON89034 (OECD identifier: MON-89 Ø34-3)
			and MON88017 (OECD identifier: MON-88Ø17-3).
			Resistance to lepidopteran insects is derived from two
			cry genes present in MON89043. Corn rootworm-
			resistance is derived from a single cry gene and
			glyphosate tolerance is derived from a 5-
			enolpyruylshikimate-3-phosphate synthase (EPSPS)-
			encoding gene from Agrobacterium tumefaciens present
			in MON88017.
A-167	MON-ØØ6Ø3-	Monsanto	Stacked insect-resistant and herbicide-tolerant maize	Zea mays
	6 × MON-	Company	hybrid derived from conventional cross-breeding of the	L. (maize)
	ØØ81Ø-6		parental lines NK603 (OECD identifier: MON-ØØ6Ø3-
			6) and MON810 (OECD identifier: MON-Ø81Ø-6).
A-168	MON-ØØ81Ø-	Monsanto	Stacked insect-resistant and increased lysine-content	Zea mays
	6 × LY038	Company	maize hybrid derived from conventional cross-breeding	L. (maize)
			of the parental lines MON810 (OECD identifier: MON-
			ØØ81Ø-6) and LY038 (OEC identifier: REN-ØØØ38-
			3).
A-169	MON-ØØ863-	Monsanto	Stacked insect-resistant and herbicide-tolerant maize	Zea mays
	5 × MON-	Company	hybrid derived from conventional cross-breeding of the	L. (maize)
	ØØ6Ø3-6		parental lines MON863 (OECD identifier: MON-
			ØØ863-5) and NK603 (OECD identifier: MON-ØØ6Ø3-
			6).
A-170	MON-ØØ863-	Monsanto	Stacked insect-resistant maize hybrid derived from	Zea mays
	5 × MON	Company	conventional cross-breeding of the parental lines	L. (maize)
	ØØ81Ø-6		MON863 (OECD identifier: MON-Ø863-5) und
			MON810 (OECD identifier: MON-ØØ81Ø-6)
A-171	MON-ØØ863-	Monsanto	Stacked insect-resistant and herbicide-tolerant maize	Zea mays
	5 × MON-	Company	hybrid derived from conventional cross-breeding of the	L. (maize)
	Ø81Ø-6 ×		stacked hybrids MON-ØØ863-5 × MON-ØØ81Ø-6 and
	MON-ØØ6Ø3-6		NK603 (OECD identifier: MON-ØØ6Ø3-6).
A-172	MON-ØØØ21-	Monsanto	Stacked insect-resistant and herbicide-tolerant maize	Zea mays
	9 × MON-	Company	hybrid derived from conventional cross-breeding of the	L. (maize)
	ØØ81Ø-6		parental lines GA21 (OECD identifier: MON-ØØØ21-9)
			and MON810 (OECD identifier: MON-ØØ81Ø-6).
A-173	MS3	Bayer Crop-	Male sterility caused by expression of the barnase	Zea mays
		Science	ribonuclease gene from Bacillus amyloliquefaciens; PPT	L. (maize)
		(Aventis	resistance was obtained via PPT acetyltransferase (PAT).
		CropScience
		(AgrEvo))
A-174	MS6	Bayer Crop-	Male sterility caused by expression of the barnase	Zea mays
		Science	ribonuclease gene from Bacillus amyloliquefaciens; PPT	L. (maize)
		(Aventis	resistance was attained via PPT acetyltransferase (PAT).
		CropScience
		(AgrEvo))
A-175	NK603	Monsanto	Introduction by gene-gun bombardment of a modified 5-	Zea mays
		Company	enolpyruvylshikimate-3-phosphate synthase (EPSPS), an	L. (maize)
			enzyme involved in the shikimate biosynthesis pathway
			for the production of the aromatic amino acids.
A-176	PV-ZMGT32		Glyphosate tolerance; US 2007-056056	Zea mays
	(NK603)			L. (maize)
A-177	PV-ZMGT32		Glyphosate tolerance; US 2007292854	Zea mays
	(nk603)			L. (maize)
A-178	PV-ZM1R13		Insect resistance (Cry3Bb); US 2006-095986	Zea mays
	(MON863)			L. (maize)
A-179	SYN-BTØ11-	Syngenta Seeds,	Stacked insect-resistant and herbicide-tolerant maize	Zea mays
	1 × MON-	Inc.	produced by conventional cross-breeding of parental	L. (maize)
	ØØØ21-9		lines BT11 (OECD unique identifier: SYN-BTØ11-1)
			and GA21 (OECD unique identifier: MON-ØØØ21-9).
A-180	T14, T25	Bayer	Glufosinate herbicide-tolerant maize produced by	Zea mays
		CropScience	inserting the phosphinothricin N-acetyltranferase (PAT)-	L. (maize)
		(Aventis	encoding gene from the aerobic actinomycete
		CropScience	Streptomyces viridochromogenes.
		(AgrEvo))
A-181	TC1507	Mycogen (c/o	Insect-resistant and glufosinate ammonium	Zea mays
		Dow	herbicide-tolerant maize produced by inserting the cry1F	L. (maize)
		AgroSciences);	gene from Bacillus thuringiensis var. aizawai and the
		Pioneer (c/o	phosphinothricin N-acetyltransferase-encoding gene
		Dupont)	from Streptomyces viridochromogenes.
A-182	TC1507 ×	DOW	Stacked insect-resistant and herbicide-tolerant maize	Zea mays
	DAS-59122-7	AgroSciences	produced by conventional cross-breeding of parental	L. (maize)
		LLC and	lines TC1507 (OECD unique identifier: DAS-Ø15Ø7-1)
		Pioneer Hi-Bred	with DAS-59122-7 (OECD unique identifier: DAS-
		International	59122-7). Resistance to lepidopteran insects is derived
		Inc.	from TC1507 due to the presence of the cry1F gene from
			Bacillus thuringiensis var. aizawai. Corn rootworm-
			resistance is derived from line DAS-59122-7 which
			contains the cry34b1 and cry35Ab1 genes from
			Bacillus. Thuringiensis strain PS149B1. Tolerance to
			glufosinate ammonium herbicide is derived from
			TC1507 from the phosphinothricin N-acetyltransferase-
			encoding gene from Streptomyces viridochromogenes.
A-183	VIP1034		Insect resistance; WO 03/052073	Zea mays
				L. (maize)

In one embodiment of the invention the plants B-1 to B-129 of table B, in total or in part, or propagation material of said plants, is treated or contacted with the active ingredient combinations of the invention, alone or in the form of compositions comprising an active ingredient combination.

TABLE B
Non-exhaustive list of transgenic plants to carry out the invention from the APHIS
database of the United States Department of Agriculture (USDA). The database can be found
on: http://www.aphis.usda.gov/animal_welfare/efoia/index.shtml.

						EA final
		Extension of			Transformation	conclusion &
No.	Petition	Petition***	Institution	Plant	Event or Line	determination
B-1	10-070-01p		Virginia Tech	Peanut	Sclerotinia	N70, P39 and
					blight-resistant	W171
B-2	09-349-01p		Dow	Soya bean	2,4-D- and	DAS-68416-4
			AgroSciences		glufosinate
					tolerance
B-3	09-328-01p		Bayer Crop	Soya bean	glyphosate and	FG72
			Science		isoxaflutole
					tolerance
B-4	09-233-01p		Dow	Maize	2,4-D and ACCase-	DAS-40278-9
					inhibitor tolerance
B-5	09-201-01p		Monsanto	Soya bean	improved fatty acid	MON-877Ø5-6
					profile
B-6	09-183-01p		Monsanto	Soya bean	stearidonic acid	MON-87769
					production
B-7	09-082-01p		Monsanto	Soya bean	Lepidopteran	MON 87701
					resistance
B-8	09-063-01p		Stine Seed	Maize	Glyphosate	HCEM485
					tolerance
B-9	09-055-01p		Monsanto	Maize	Drought tolerance	MON 87460
B-10	09-015-01p		BASF Plant	Soya bean	Imidazolinon	BPS-CV127-9
			Science, LLC		tolerance	Soya bean
B-11	08-366-01p		ArborGen	Eucalyptus	Freeze tolerance,	ARB-FTE1-08
					fertility altered
B-12	08-340-01p		Bayer	Cotton	Glufosinate	T304-40XGHB119
					tolerance, insect
					resistance
B-13	08-338-01p		Pioneer	Maize	Male sterility,	DP-32138-1
					fertility restored,
					visual marker
B-14	08-315-01p		Florigene	Rose	Altered flower	IFD-524Ø1-4 and
					color	IFD-529Ø1-9
B-15	07-108-01p		Syngenta	Cotton	Lepidopteran	COT67B
					resistance
B-16	06-354-01p		Pioneer	Soya bean	High oleic acid	DP-3Ø5423-1
B-17					content
B-18	05-280-01p		Syngenta	Maize	Thermostable	3272
B-19					alpha-amylase
B-20	04-110-01p		Monsanto &	Alfalfa	Glyphosate	J101, J163
B-21			Forage		tolerance
B-22			Genetics
B-23
B-24	03-104-01p		Monsanto &	Creeping	Glyphosate	ASR368
B-25			Scotts	bentgrass	tolerance
B-26
B-27
B-28
B-29
B-30	07-253-01p		Syngenta	Maize	Lepidopteran	MIR-162 Maize
B-31					resistance
B-32	07-152-01p		Pioneer	Maize	Glyphosate &	DP-098140-6
B-33					imidazolinone
					tolerance
B-34	04-337-01p		University of	Papaya	Papaya ringspot	X17-2
B-35			Florida		virus-resistant
B-36	06-332-01p		Bayer	Cotton	Glyphosate	GHB614
B-37			CropScience		tolerance
B-38	06-298-01p		Monsanto	Maize	European Corn	MON 89034
B-39					Borer resistance
B-40	06-271-01p		Pioneer	Soya bean	Glyphosate &	356043
B-41					acetolactate	(DP-356Ø43-5)
					synthase tolerance
B-42	06-234-01p	98-329-01p	Bayer	Rice	Phosphinothricin	LLRICE601
B-43			CropScience		tolerance
B-44	06-178-01p		Monsanto	Soya bean	Glyphosate	MON 89788
B-45					tolerance
B-46	04-362-01p		Syngenta	Maize	Corn rootworm-	MIR604
B-47					protected
B-48
B-49	04-264-01p		ARS	Plum	Plum Pox	C5
B-50					virus-resistant
B-51	04-229-01p		Monsanto	Maize	High lysine content	LY038
B-52
B-53	04-125-01p		Monsanto	Maize	Corn rootworm-	88017
B-54					resistance
B-55	04-086-01p		Monsanto	Cotton	Glyphosate	MON 88913
B-56					tolerance
B-57
B-58	03-353-01p		Dow	Maize	Corn rootworm-	59122
B-59					resistance
B-60	03-323-01p		Monsanto	Sugar beet	Glyphosate	H7-1
B-61					tolerance
B-62	03-181-01p	00-136-01p	Dow	Maize	Lepidopteran	TC-6275
B-63					resistance &
					phosphinothricin
					tolerance
B-64	03-155-01p		Syngenta	Cotton	Lepidopteran	COT 102
B-65					resistance
B-66	03-036-01p		Mycogen/Dow	Cotton	Lepidopteran	281-24-236
B-67					resistance
B-68	03-036-02p		Mycogen/Dow	Cotton	Lepidopteran	3006-210-23
B-69					resistance
B-70	02-042-01p		Aventis	Cotton	Phosphinothricin	LLCotton25
					tolerance
B-71	01-324-01p	98-216-01p	Monsanto	Oilseed	Glyphosate	RT200
				rape	tolerance
B-72	01-206-01p	98-278-01p	Aventis	Oilseed	Phosphinothricin-	MS1 & RF1/RF2
				rape	tolerance &
					pollination control
B-73	01-206-02p	97-205-01p	Aventis	Oilseed	Phosphinothricin	Topas 19/2
				rape	tolerance
B-74	01-137-01p		Monsanto	Maize	Corn rootworm-	Mon 863
					resistance
B-75	01-121-01p		Vector	Tobacco	Reduced nicotine	Vector 21-41
					content
B-76	00-342-01p		Monsanto	Cotton	Lepidopteran	Cotton Event
					resistance	15985
B-77	00-136-01p		Mycogen c/o	Maize	Lepidopteran	Line 1507
			Dow & Pioneer		resistance &
					phosphinothricin
					tolerance
B-78	00-011-01p	97-099-01p	Monsanto	Maize	Glyphosate	NK603
					tolerance
B-79	99-173-01p	97-204-01p	Monsanto	Potato	PLRV & CPB	RBMT22-82
					resistance
B-80	98-349-01p	95-228-01p	AgrEvo	Maize	Phosphinothricin	MS6
					tolerance and male
					sterility
B-81	98-335-01p		U. of	Flax	Tolerant to soil	CDC Triffid
			Saskatchewan		residues of
					sulfonylurea
					herbicide
B-82	98-329-01p		AgrEvo	Rice	Phosphinothricin	LLRICE06,
					tolerance	LLRICE62
B-83	98-278-01p		AgrEvo	Oilseed	Phosphinothricin	MS8 & RF3
				rape	tolerance &
					pollination control
B-84	98-238-01p		AgrEvo	Soya bean	Phosphinothricin	GU262
					tolerance
B-85	98-216-01p		Monsanto	Oilseed	Glyphosate	RT73
				rape	tolerance
B-86	98-173-01p		Novartis Seeds	Beet	Glyphosate	GTSB77
			& Monsanto		tolerance
B-87	98-014-01p	96-068-01p	AgrEvo	Soya bean	Phosphinothricin	A5547-127
					tolerance
B-88	97-342-01p		Pioneer	Maize	Male sterility &	676, 678, 680
					phosphinothricin
					tolerance
B-89	97-339-01p		Monsanto	Potato	CPB & PVY	RBMT15-101,
					resistance	SEMT15-02,
						SEMT15-15
B-90	97-336-01p		AgrEvo	Beet	Phosphinothricin	T-120-7
					tolerance
B-91	97-287-01p		Monsanto	Tomato	Lepidopteran	5345
					resistance
B-92	97-265-01p		AgrEvo	Maize	Phosphinothricin	CBH-351
					tolerance &
					Lepidopteran
					resistance
B-93	97-205-01p		AgrEvo	Oilseed	Phosphinothricin	T45
				rape	tolerance
B-94	97-204-01p		Monsanto	Potato	CPB & PLRV	RBMT21-129 &
					resistance	RBMT21-350
B-95	97-148-01p		Bejo	Cichorium	Male sterility	RM3-3, RM3-4,
				intybus		RM3-6
B-96	97-099-01p		Monsanto	Maize	Glyphosate	GA21
					tolerance
B-97	97-013-01p		Calgene	Cotton	Bromoxynil	Events 31807 &
					tolerance &	31808
					Lepidopteran
					resistance
B-98	97-008-01p		Du Pont	Soya bean	Oil profile	G94-1, G94-19,
					altered	G-168
B-99	96-317-01p		Monsanto	Maize	Glyphosate	MON802
					tolerance & ECB
					resistance
B-100	96-291-01p		DeKalb	Maize	European Corn	DBT418
					Borer resistance
B-101	96-248-01p	92-196-01p	Calgene	Tomato	Fruit ripening	1 additional
					altered	FLAVRSAVR line
B-102	96-068-01p		AgrEvo	Soya bean	Phosphinothricin	W62, W98, A2704-
					tolerance	12, A2704-
						21, A5547-35
B-103	96-051-01p		Cornell U	Papaya	PRSV resistance	55-1, 63-1
B-104	96-017-01p	95-093-01p	Monsanto	Maize	European Corn	MON809 &
					Borer resistance	MON810
B-105	95-352-01p		Asgrow	Summer	CMV, ZYMV,	CZW-3
				squash	WMV2 resistance
B-106	95-338-01p		Monsanto	Potato	CPB resistance	SBT02-5 & -7,
						ATBT04-6
						&-27, -30, -31, -36
B-107	95-324-01p		Agritope	Tomato	Fruit ripening	35 1 N
					altered
B-108	95-256-01p		Du Pont	Cotton	Sulfonylurea	19-51a
					resistance
B-109	95-228-01p		Plant Genetix	Maize	Male sterile	MS3
			Systems
B-110	95-195-01p		Northrup	Maize	European Corn	Bt11
			King		Borer resistance
B-111	95-179-01p	92-196-01p	Calgene	Tomato	Fruit ripening	2 additional
					altered	FLAVRSAVR-
						lines
B-112	95-145-01p		DeKalb	Maize	Phosphinothricin	B16
					tolerance
B-113	95-093-01p		Monsanto	Maize	Lepidopteran	MON 80100
					resistance
B-114	95-053-01p		Monsanto	Tomato	Fruit ripening	8338
					altered
B-115	95-045-01p		Monsanto	Cotton	Glyphosate	1445, 1698
					tolerance
B-116	95-030-01p	92-196-01p	Calgene	Tomato	Fruit ripening	20 additional
					altered	FLAVRSAVR
						lines
B-117	94-357-01p		AgrEvo	Maize	Phosphinothricin	T14, T25
					tolerance
B-118	94-319-01p		Ciba Seeds	Maize	Lepidopteran	Event 176
					resistance
B-119	94-308-01p		Monsanto	Cotton	Lepidopteran	531, 757, 1076
					resistance
B-120	94-290-01p		Zeneca &	Tomato	Fruit	B, Da, F
			Petoseed		polygalacturonase
					level decreased
B-121	94-257-01p		Monsanto	Potato	Coleopteran	BT6, BT10, BT12,
					resistance	BT16, BT17,
						BT18, BT23
B-122	94-230-01p	92-196-01p	Calgene	Tomato	Fruit ripening	9 additional
					altered	FLAVRSAVR
						lines
B-123	94-228-01p		DNA Plant	Tomato	Fruit ripening	1345-4
			Tech		altered
B-124	94-227-01p	92-196-01p	Calgene	Tomato	Fruit ripening	Line N73 1436-
					altered	111
B-125	94-090-01p		Calgene	Oilseed	Oil profile	pCGN3828-
				rape	altered	212/86- 18 & 23
B-126	93-258-01p		Monsanto	Soya bean	Glyphosate	40-3-2
					tolerance
B-127	93-196-01p		Calgene	Cotton	Bromoxynil	BXN
					tolerance
B-128	92-204-01p		Upjohn	Summer	WMV2 & ZYMV	ZW-20
				squash	resistance
B-129	92-196-01p		Calgene	Tomato	Fruit ripening	FLAVR SAVR
					altered
Abbreviations used in this table:
CMV—cucumber mosaic virus,
CPB—Colorado potato beetle,
PLRV—potato leafroll virus,
PRSV—papaya ringspot virus,
PVY—potato virus Y,
WMV2—watermelon mosaic virus 2
ZYMV—zucchini yellow mosaic virus

In one embodiment the plants which comprise a transgenic event as per D-1 to D-48 of table 1) or express such a trait, in whole or in part, or propagation material of these plants, are or is contacted or treated with the active ingredient combinations of the invention, alone or in the form of compositions which comprise an active ingredient combination.

TABLE D
Non-exhaustive list of transgenic events and traits the invention
can be worked on, with reference to patent applications.

No.	Plant species	Transgenic event	Trait	Patent reference
D-1	Maize	PV-ZMGT32 (NK603)	Glyphosate tolerance	US 2007-056056
D-2	Maize	MIR604	Insect resistance (Cry3a055)	EP-A 1 737 290
D-3	Maize	LY038	High lysine content	U.S. Pat. No. 7,157,281
D-4	Maize	3272	Self-processing maize	US 2006-230473
			(alpha-amylase)
D-5	Maize	PV-ZMIR13 (MON863)	Insect resistance (Cry3Bb)	US 2006-095986
D-6	Maize	DAS-59122-7	Insect resistance	US 2006-070139
			(Cry34Ab1/Cry35Ab1)
D-7	Maize	TC1507	Insect resistance (Cry1F)	U.S. Pat. No. 7,435,807
D-8	Maize	MON810	Insect resistance (Cry1Ab)	US 2004-180373
D-9	Maize	VIP1034	Insect resistance	WO 03/052073
D-10	Maize	B16	Glufosinate resistance	US 2003-126634
D-11	Maize	GA21	Glyphosate resistance	U.S. Pat. No. 6,040,497
D-12	Maize	GG25	Glyphosate resistance	U.S. Pat. No. 6,040,497
D-13	Maize	GJ11	Glyphosate resistance	U.S. Pat. No. 6,040,497
D-14	Maize	FI117	Glyphosate resistance	U.S. Pat. No. 6,040,497
D-15	Maize	GAT-ZM1	Glufosinate tolerance	WO 01/51654
D-16	Maize	DP-098140-6	Glyphosate tolerance/ALS-	WO 2008/112019
			inhibitor tolerance
D-17	Wheat	Event 1	Fusarium resistance	CA 2561992
			(trichothecene 3-O-
			acetyltransferase)
D-18	Sugar beet	T227-1	Glyphosate tolerance	US 2004-117870
D-19	Sugar beet	H7-1	Glyphosate tolerance	WO 2004-074492
D-20	Soya bean	MON89788	Glyphosate tolerance	US 2006-282915
D-21	Soya bean	A2704-12	Glufosinate tolerance	WO 2006/108674
D-22	Soya bean	A5547-35	Glufosinate tolerance	WO 2006/108675
D-23	Soya bean	DP-305423-1	High oleic acid/ALS-	WO 2008/054747
			inhibitor tolerance
D-24	Rice	GAT-OS2	Glufosinate tolerance	WO 01/83818
D-25	Rice	GAT-OS3	Glufosinate tolerance	US 2008-289060
D-26	Rice	PE-7	Insect resistance (Cry1Ac)	WO 2008/114282
D-27	Oilseed rape	MS-B2	Male sterility	WO 01/31042
D-28	Oilseed rape	MS-BN1/RF-BN1	Male sterility/restoration	WO 01/41558
D-29	Oilseed rape	RT73	Glyphosate resistance	WO 02/36831
D-30	Cotton	CE43-67B	Insect resistance (Cry1Ab)	WO 2006/128573
D-31	Cotton	CE46-02A	Insect resistance (Cry1Ab)	WO 2006/128572
D-32	Cotton	CE44-69D	Insect resistance (Cry1Ab)	WO 2006/128571
D-33	Cotton	1143-14A	Insect resistance (Cry1Ab)	WO 2006/128569
D-34	Cotton	1143-51B	Insect resistance (Cry1Ab)	WO 2006/128570
D-35	Cotton	T342-142	Insect resistance (Cry1Ab)	WO 2006/128568
D-36	Cotton	event3006-210-23	Insect resistance (Cry1Ac)	WO 2005/103266
D-37	Cotton	PV-GHGT07 (1445)	Glyphosate tolerance	US 2004-148666
D-38	Cotton	MON88913	Glyphosate tolerance	WO 2004/072235
D-39	Cotton	EE-GH3	Glyphosate tolerance	WO 2007/017186
D-40	Cotton	T304-40	Insect resistance (Cry1Ab)	WO2008/122406
D-41	Cotton	Cot202	Insect resistance (VIP3)	US 2007-067868
D-42	Cotton	LLcotton25	Glufosinate resistance	WO 2007/017186
D-43	Cotton	EE-GH5	Insect resistance (Cry1Ab)	WO 2008/122406
D-44	Cotton	event 281-24-236	Insect resistance (Cry1F)	WO 2005/103266
D-45	Cotton	Cot102	Insect resistance (Vip3A)	US 2006-130175
D-46	Cotton	MON 15985	Insect resistance	US 2004-250317
			(Cry1A/Cry2Ab)
D-47	Bentgrass	Asr-368	Glyphosate tolerance	US 2006-162007
D-48	Aubergine	EE-1	Insect resistance (Cry1Ac)	WO 2007/091277

In one embodiment the plants which comprise a transgenic event as per E-1 to E-50 of table E or express such a trait, in whole or in part, or propagation material of these plants, are or is contacted or treated with the active ingredient combinations of the invention, a one or in the form of compositions which comprise an active ingredient coinbination.

TABLE E
Non-exhaustive list of transgenic events and traits and their trade names.

No.	Trade name	Plant	Company	Genetically modified properties	Additional information
E-1	Roundup	Beta vulgaris	Monsanto	Glyphosate tolerance
	Ready ®	(sugar beet)	Company
E-2	InVigor ®	Brassica napus	Bayer	Canola rape was genetically modified with the
		(Argentine	CropScience	following result:
		canola rape)		Ø expression of a gene which confers tolerance
				to the herbicide glyfosinate ammonium;
				Ø introduction of a novel hybrid breeding system
				for canola rape which is based on genetically
				modified male-sterility (MS) and fertility-
				restorer (RF) lines;
				Ø expression of a gene for resistance to
				antibiotics.
E-3	Liberty Link ®	Brassica napus	BayerCrop-	Phosphinotricin tolerance
		(Argentine	Science
		canola rape)
E-4	Roundup	Brassica napus	Monsanto	Glyphosate tolerance
	Ready ®	(canola rape)	Company
E-5	Clearfield ®	(Canola rape)	BASF	Non-GMO, imazamox tolerance
			Corporation
E-6	Optimum ™	Glycine max	Pioneer Hi-	Glyphosate and ALS herbicide tolerance
	GAT ™	L. (soya bean)	Bred
			International,
			Inc
E-7	Roundup	Glycine max	Monsanto	Glyphosate tolerance
	Ready ®	L. (soya bean)	Company
E-8	Roundup	Glycine max	Monsanto	Glyphosate tolerance
	RReady2Yiel ™	L. (soya bean)	Company
E-9	STS ®	Glycine max	DuPont	Sulfonylurea tolerance
		L. (soya bean)
E-10	YIELD	Glycine max	Monsanto
	GARD ®	L. (soya bean)	Company
E-11	AFD ®	Gossypium	Bayer	The lines include, for example, AFD5062LL,
		hirsutum	CropScience	AFD5064F, AFD 5065B2F; AFD seed is available
		L. (cotton)		in a wide range of varieties with integrated
				technology such as, for example, the Bollgard ®,
				Bollgard II, Roundup Ready, Roundup
				Ready Flex and LibertyLink ® technologies
E-12	Bollgard II ®	Gossypium	Monsanto	MON 15985 event: Cry2(A)b1; Cry1A(c)
		hirsutum	Company
		L. (cotton)
E-13	Bollgard ®	Gossypium	Monsanto	Cry 1Ac
		hirsutum	Company
		L. (cotton)
E-14	FiberMax ®	Gossypium	Bayer
		hirsutum	CropScience
		L. (cotton)
E-15	Liberty Link ®	Gossypium	Bayer	Phosphinotricin tolerance
		hirsutum	CropScience
		L. (cotton)
E-16	Nucotn 33B	Gossypium	Delta Pine	Bt toxin in the lines from Delta Pine: CrylAc
		hirsutum	and Land
		L. (cotton)
E-17	Nucotn 35B	Gossypium	Delta Pine	Bt toxin in the lines from Delta Pine: CrylAc
		hirsutum	and Land
		L. (cotton)
E-18	Nucotn ®	Gossypium	Delta Pine	Bt toxin in the lines from Delta Pine
		hirsutum	and Land
		L. (cotton)
E-19	PhytoGen ™	Gossypium	PhytoGen Seed	Comprises varieties which contain, for
		hirsutum	Company, Dow	example, Roundup Ready flex, Widestrike
		L. (cotton)	AgroSciences
			LLC
E-20	Roundup	Gossypium	Monsanto	Glyphosate tolerance
	Ready Flex ®	hirsutum	Company
		L. (cotton)
E-21	Roundup	Gossypium	Monsanto	Glyphosate tolerance
	Ready ®	hirsutum	Company
		L. (cotton)
E-22	Widestrike ™	Gossypium	Dow	Cry1F and Cry1Ac	Monsanto/Dow
		hirsutum	AgroSciences
		L. (cotton)	LLC
E-23	YIELD	Gossypium	Monsanto		http://www.garstseed.com/
	GARD ®	hirsutum	Company		GarstClient/Technology/
		L. (cotton)			agrisure.aspx
E-24	Roundup	Medicago	Monsanto	Glyphosate tolerance
	Ready ®	sativa (alfalfa)	Company
E-25	Clearfield ®	Oryza sativa	BASF	Non-GMO, imazamox tolerance
		(rice)	Corporation
E-26	NewLeaf ®	Solanum	Monsanto	Resistance to infection by potato leafroll virus
		tuberosum	Company	(PLRV) and feeding damage by the Colorado
		L. (potato)		beetle Leptinotarsa decemlineata
E-27	NewLeaf ®	Solanum	Monsanto	Resistance to infection by potato leafroll virus	http://www.dowagro.com/
	plus	tuberosum	Company	(PLRV) and feeding damage by the Colorado	phytogen/index.htm
		L. (potato)		beetle Leptinotarsa decemlineata
E-28	Protecta ®	Solanum
		tuberosum
		L. (potato)
E-29	Clearfield ®	Sunflower	BASF	Non-GMO, imazamox tolerance
			Corporation
E-30	Roundup	Triticum	Monsanto	Glyphosate tolerance, NK603
	Ready ®	aestivum	Company
		(wheat)
E-31	Clearfield ®	Wheat	BASF	Non-GMO, imazamox tolerance
			Corporation
E-32	Agrisure ®	Zea mays	Syngenta	These include Agrisure CB/LL (BT 11 event plus
	(Family)	L. (maize)	Seeds, Inc.	phosphinotricin tolerance as the result of
				GA21 event); Agrisure CB/LL/RW (Bt 11 event,
				modified synthetic Cry3A gene, phosphinotricin
				tolerance as the result of GA21 event);
				Agrisure GT (glyphosate tolerance); Agrisure
				GT/CB/LL(glyphosate tolerance and
				phosphinotricin tolerance as the result of
				GA21 event, Bt 11 event); Agrisure 3000GT
				(CB/LL/RW/GT: glyphosate and phosphinotricin
				tolerance as the result of GA21 event;
				Bt 11 event, modified synthetic Cry3A gene);
				Agrisure GT/RW (glyphosate tolerance, modified
				synthetic Cry3A gene); Agrisure RW (modified
				synthetic Cry3A gene); future traits
E-33	BiteGard ®	Zea mays	Novartis Seeds	cry1A(b) gene
		L. (maize)
E-34	Bt-Xtra ®	Zea mays	DEKALB	cry1Ac gene
		L. (maize)	Genetics
			Corporation
E-35	Clearfield ®	Zea mays	BASF	Non-GMO, imazamox tolerance
		L. (maize)	Corporation
E-36	Herculex ®	Zea mays	Dow
	(Familie)	L. (maize)	AgroSciences
			LLC
E-37	IMI ®	Zea mays	DuPont	Imidazolinone tolerance
		L. (maize)
E-38	KnockOut ®	Zea mays	Syngenta	SYN-EV176-9: cry1A(b) gene
		L. (maize)	Seeds, Inc,
E-39	Mavera ®	Zea mays	Renessen	High lysine	http://www.dowagro.com/
		L. (maize)	LLC		widestrike/
E-40	NatureGard ®	Zea mays	Mycogen	cry1A(b) gene
		L. (maize)
E-41	Roundup	Zea mays	Monsanto	Glyphosate tolerance	http://www.starlinkcorn.com/
	Ready ®	L. (maize)	Company		starlinkcorn.htm
E-42	Roundup	Zea mays	Monsanto	Glyphosate tolerance
	Ready ®2	L. (maize)	Company
E-43	SmartStax	Zea mays	Monsanto	Combination of eight genes
		L. (maize)	Company
E-44	StarLink ®	Zea mays	Aventis	Cry9c gene
		L. (maize)	CropScience −>
			Bayer
			CropScience
E-45	STS ®	Zea mays	DuPont	Sulfonylurea tolerance
		L. (maize)
E-46	YIELD	Zea mays	Monsanto	Mon810, Cry1Ab1; resistance to the	http://www.dowagro.com/
	GARD ®	L. (maize)	Company	European Corn Borer	herculex/about/herculexfamily/
E-47	YieldGard ®	Zea mays	Monsanto	Mon810 × Mon863, dual resistance to
	Plus	L. (maize)	Company	European Corn Borer and corn rootworm
E-48	YieldGard ®	Zea mays	Monsanto	Mon863, Cry3Bb1, resistance to corn
	Rootworm	L. (maize)	Company	rootworm
E-49	YieldGard ®	Zea mays	Monsanto	Stacked traits
	VT	L. (Maize)	Company
E-50	YieldMaker ™	Zea mays	DEKALB	Contains Roundup Ready 2 technology,
		L. (Maize)	Genetics	YieldGard VT, YieldGard Corn Borer,
			Corporation	YieldGard Rootworm and YieldGard Plus

Transgenic crop plants that can be treated in accordance with the invention are preferably plants Which comprise transformation events (transformation-integration events) or a. combination of transformation events (transformation-integration events) and which, for example, are listed in the databases for various national or regional registration authorities, including event 1143-14A (cotton, insect control, not filed, described in WO2006/128569); event 1143-51B (cotton, insect control, not filed, described in WO2006/128570); event 1445 (cotton, herbicide tolerance, not filed, described in US2002120964 or WO2002/034946); event 17053 (rice, herbicide tolerance, filed as PTA-9843, described in WO2010/117737); event 17314 (rice, herbicide tolerance, filed as PTA-9844, described in WO2010/117735); event 281-24-236 (cotton, insect control—herbicide tolerance, filed as PTA-(233, described in WO2005/103266 or US2005216969); event 3006-210-23 (cotton, insect control—herbicide tolerance, filed as PTA-6233, described in US2007143876 or WO2005/103266); event 3272 (maize, quality trait, filed as PTA-9972, described in WO2006098952 or US2006230473); event 40416 (maize, insect control—herbicide tolerance, filed as ATCC PTA-11508, described in WO2011/075593); event 43A47 (maize, insect control—tolerance, filed as ATCC PTA-11509, described in WO2011/075595); event 5307 (maize, insect control, filed as ATCC PTA-9561, described in WO2010/077816); event ASR-368 [bent grass, herbicide tolerance, filed as ATCC PTA-4816, described in US2006162007 or WO2004053062]; event B16 (Maize, herbicide tolerance, not filed, described in US2003126634); event BPS-CV127-9 (soya bean, herbicide tolerance, filed as NCIMB No. 41603, described in WO2010/080829); event CE43-67B (cotton, insect control, filed as DSM ACC2724, described in US2009217423 or WO2006/128573); event CE44-69D (cotton, insect control, not filed, described in US20100024077); event CE44-69D (cotton, insect control, not filed, described in WO2006/128571); event CE46-02A (cotton, insect control, not filed, described in WO2006/128572); event car102 (cotton, insect control, not filed, described in US2006130175 or WO2004039986); event COT202 (cotton, insect control, not filed, described in US2007067868 or WO2005054479); event COT203 (cotton, insect control, not filed, described in WO2005/054480); event DAS40278 (maize, herbicide tolerance, filed as ATCC PTA-10244, described in WO2011/022469); event DAS-59122-7 (maize, insect control—herbicide tolerance, filed as ATCC PTA 11384, described in US2006070139); event D.kS-59132 (maize, insect control—herbicide tolerance, not filed, described in WO2009/100188); event DAS68416 (soya bean, herbicide tolerance, filed as ATCC PTA-10442, described in WO2011/066384 or 11/02011/066360); event DP-098140-6 (maize, herbicide tolerance, filed as ATCC PTA-8296, described in US2009137395 or WO2008/112019); event DP-305423-1 (soya bean, quality trait, not filed, described in US2008312082 or WO2008/054747); event DP-32138-1 (maize, hybrid system, filed as ATCC PTA-9158, described in US20090210970 or WO2009/103049); event DP-356043-5 (soya bean, herbicide tolerance, filed as ATCC PTA-8287, described in US20100184079 or WO2008/002872); event EE-1 (aubergine, insect control, not filed, described in WO2007/091277); event FI117 (maize, herbicide tolerance, filed as ATCC 209031, described in US2006059581 or WO1998/044140); event GA21 (maize, herbicide tolerance, filed as ATCC 209033, described in US2005086719 or WO1998/044140); event. GG25 (maize, herbicide tolerance, filed as ATCC 209032, described in US2005188434 or WO1998/044140); event GHB119 (cotton, insect control—herbicide tolerance, filed as ATCC PTA-8398, described in WO2008/151780); event GHB614 (cotton, herbicide tolerance, filed as ATCC PTA-6878, described in US2010050282 or WO2007/017186); event GJ11 (maize, herbicide tolerance, filed as ATCC 209030, described in US2005188434 or WO1998/044140); event GM RZ13 (sugar beet, virus resistance, filed as NCIMB-41601, described in WO2010/076212); event H7-1 (sugar beet, herbicide tolerance, filed as NCIMB 41158 or NCIMB 41159, described in US2004172669 or WO2004/074492); event JOPUN1 (wheat, fungus resistance, not filed, described in US2008064032); event LL27 (soya bean, herbicide tolerance, filed as NCIMB41658, described in WO2006/108674 or US2008320616); event LL55 (soya bean, herbicide tolerance, filed as NCIMB 41660, described in WO2006/108675 or US2008196127); event LLcotton25 (cotton, herbicide tolerance, filed as ATCC PTA-3343, described in WO2003013224 or US2003097687); event LLRICE06 (rice, herbicide tolerance, flied as ATCC-23352, described in U.S. Pat. No. 6,468,747 or WO2000/026345); event LLRICE601 (rice, herbicide tolerance, filed as ATCC PTA-2600, described in US20082289060 or WO2000/026356); event LY038 (maize, quality trait, filed as ATCC PTA-5623, described in US2007028322 or 11%02005061720); event MIR162 (maize, insect control, flied as PTA-8166, described in US2009300784 or WO2007/142840); event MIR604 (maize, insect control, not filed, described in US2008167456 or WO2005103301); event MON15985 (cotton, insect control, filed as ATCC PTA-2516, described in US2004-250317 or WO2002/100163); event MON810 (maize, insect control, not filed, described in US2002102582); event MON863 (maize, insect control, filed as ATCC PTA-2605, described in WO2004/011601 or US2006095986); event MON87427 (maize, pollination control, filed as ATCC PTA-7899, described in WO2011/062904); event MON87460 (maize, stress tolerance, filed as ATCC PTA-8910, described in WO2009/111263 or US2011.0138504); event MON87701 (soya bean, insect control, filed as ATCC PTA-8194, described in US2009130071 or WO2009/064652); event MON87705 (soya bean, quality trait—herbicide tolerance, filed as ATCC PTA-9241, described in US20100080887 or WO2010/037016); event MON87708 (soya bean, herbicide tolerance, filed as ATCC PTA9670, described in WO2011/034704); event MON87754 (soya bean, quality feature, filed as ATCC PTA-9385, described in WO2010/024976); event MON87769 (soya bean, quality trait, filed as ATCC PTA-8911, described in US20110067141 or WO2009/102873); event MON88017 (maize, insect control—herbicide tolerance, filed as ATCC PTA-5582, described in US2008028482 or WO2005/059103); event MON88913 (cotton, herbicide tolerance, filed as ATCC PTA-4854, described in WO2004/072235 or US2006059590); event MON89034 (maize, insect control, filed as ATCC PTA-7455, described in WO2007/1.40256 or US2008260932); event MON89788 (soya bean, herbicide tolerance, filed as ATCC PTA-6708, described in US2006282915 or WO2006/130436); event MS11 (oilseed rape, pollination control—herbicide tolerance, filed as ATCC PTA-850 or PTA-2485, described in WO2001/031042); event MS8 (oilseed rape, pollination control herbicide tolerance, filed as ATCC PTA-730, described in WO2001/041558 or US2003188347); event NK603 (maize, herbicide tolerance, filed as ATCC PTA-2478, described in US2007-292854); event PE-7 (rice, insect control, not flied, described in WO2008/114282); event RF3 (oilseed rape, pollination control herbicide tolerance, filed as ATCC PTA-730, described in WO2001/041558 or US2003188347); event RT73 (oilseed rape, herbicide tolerance, not filed, described in WO2002/036831 or US2008070260); event T227-1 (sugar beet, herbicide tolerance, not filed, described in WO2002/44407 or US2009265817); event T25 (maize, herbicide tolerance, not filed, described in US2001029014 or WO2001/051654); event T304-40 (cotton, insect control—herbicide tolerance, filed as ATCC PTA-8171, described in US2010077501 or WO2008/122406); event T342-142 (cotton, insect control, not filed, described in WO2006/128568); event TC1507 (maize, insect control herbicide tolerance, not filed, described in US2005039226 or WO2004/099447); event VIP1034 (maize, insect control—herbicide tolerance, filed as ATCC PTA-3925, described in WO2003/052073); event 32316 (maize, insect control—herbicide tolerance, filed as PTA-11507, described in WO2011/084632); event 4114 (maize, insect control—herbicide tolerance, tiled as PTA-1 1506, described in WO201 1/084621).

The plants listed can be treated in accordance with the invention in a particularly advantageous manner with the inventive active ingredient mixture. The preferred ranges staled above for the mixtures also apply to the treatment of these plants. Particular emphasis is given to the treatment of plants with the mixtures specifically mentioned in the present text.

The control of animal pests, especially of nematodes, by treating the seed of plants has been known for a long time and is the subject of continual improvements. However, in the treatment of seed, a number of problems are encountered which cannot always be resolved in a satisfactory manner. Thus, it is desirable to develop methods for protecting the seed and the germinating plant which at least significantly reduce, or make superfluous, the additional application of crop protection agents after sowing or after the emergence of the plants. It is additionally desirable to optimize the amount of active ingredient employed in such a way as to provide maximum protection for the seed and the germinating plant from attack by animal pests, especially nematodes, but without damaging the plant itself by the active ingredient used. In particular, methods for the treatment of seed should a sotake into consideration the intrinsic insecticidal properties of transgenic plants in order to achieve optimum protection of the seed and the germinating plant with a minimum of crop protection agents being employed.

The present invention therefore also relates especially to a method for the protection of seed and germinating plants from attack by animal pests, especially by nematodes, and also to a method for increasing yields, by treating the seed with an inventive composition.

The invention likewise relates to the use of the inventive compositions for the treatment of seed for protecting the seed and the germinating plant from animal pests, especially from nematodes, and. also for increasing yields.

The invention further relates to seed which has been treated with an inventive composition for protection from animal pests, especial y nematodes.

One of the advantages of the present invention is that the particular systemic properties of the inventive compositions mean that treatment of the seed with these compositions not only protects the seed itself, but also the resulting plants after emergence, front animal pests, especially nematodes. in this manner, the immediate treatment of the crop at the time of sowing or shortly thereafter can be dispensed with.

It is also considered to be advantageous that the inventive mixtures can also be used for transgenic seed in particular.

Formulations

The active ingredient combinations can be converted to the customary formulations such as solutions, emulsions, wettable powders, suspensions, powders, dusts, pastes, soluble powders, granules, suspension-emulsion concentrates, natural and synthetic materials impregnated with active ingredient, and microencapsulations in polymeric materials, for the foliar and soil applications.

These formulations are produced in a known manner, for example by mixing the active ingredients with extenders, that is, liquid solvents and/or solid carriers, optionally with the use of surfactants, that is, emulsifiers and/or dispersants, and/or foam formers.

If the extender used comprises water, it is also possible, for example, to use organic solvents as cosolvents. The following are essentially suitable as liquid solvents: aromatics such as xylene, toluene or alkyinaphthalenes, chlorinated aromatics or chlorinated aliphatic hydrocarbons such as chlorobenzenes, chloroethylenes or methylene chloride, aliphatic hydrocarbons such as cyclohexane or paraffins, for example mineral oil fractions, mineral and vegetable oils, alcohols such as butanol or glycol and their ethers and esters, ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone, strongly polar solvents such as dimethylformamide and dimethyl suifoxide, and water.

Suitable solid carriers are:

for example ammoniam safis and ground natural minerals such as kaolins, clays, talc, chalk, quartz, attapulgite, montmorillonite or diatomaceous earth, and ground synthetic minerals such as highly disperse silica, alumina and silicates; suitable solid carriers for granules are: for example crushed and fractionated natural rocks such as calcite, marble, pumice, sepiolite and dolomite, or else synthetic granules of inorganic and organic meals, and granules of organic material such as sawdust, coconut shells, maize cobs and tobacco stalks; suitable emulsifiers and/or foam formers are: for example nonionic and anionic emulsifiers such as polyoxyethylene fatty acid. esters, polyoxyethylene fatty alcohol ethers, for example alkylaryl polyglycol ethers, alkylsulfon.ates, alkyl sulfates, arylsulfonates, or else protein hydrolysates; suitable dispersants are: for example lignosulfite waste liquors and methylcellulose.

Tackifiers such as carboxymethylcellulose and natural and synthetic polymers in the form of powders, granules or latices, such as gum arabic, polyvinyl alcohol and polyvinyl acetate, or else natural phospholipids such as cephalins and lecithins and synthetic phospholipids can be used in the formulations. Other possible additives are mineral and vegetable oils.

It is possible to use colorants such as inorganic pigments, for example iron oxide, titanium oxide and Prussian Blue, and organic dyes such as alizarin dyes, azo dyes and metal plithalocyanine dyes, and trace nutrients such as salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc.

The formulations generally contain between 0.1 and 95 wt % of active ingredient, preferably between 0.5 and 90%.

The inventive active ingredient combinations may be present in commercially standard formulations and in the use forms, prepared from these formulations, as a mixture with other active ingredients, such as insecticides, attractants, sterilants, bactericides, acaricides, nematicides, fungicides, growth-regulating substances or herbicides. The insecticides include, for example, phosphates, carbamates, carboxylates, chlorinated hydrocarbons, phenylureas and substances produced by microorganisms, etc.

Mixing with other known active ingredients such as herbicides or with fertilizers and growth regulators is also possible.

When used as insecticides, the inventive active ingredient combinations may additionally be present in their commercially available formulations and in the use forms, prepared from these formulations, as a mixture with synergists. Synergists are compounds which enhance the action of the active ingredients, without it being necessary for the synergist added to be active itself.

The active ingredient content of the use forms prepared from the commercially available formulations may vary within wide limits. The active ingredient concentration of the use forms may be front 0.0000001 to 95 wt % of active ingredient, preferably between 0.0001 and 50 wt %.

The compounds are employed in a customary manner appropriate for the use forms.

Use Forms

When the active ingredients of the invention are used for controlling animal pests, more particularly nematodes, the application rates may be varied within a relatively wide range, depending on the mode of application. The application rate of the active ingredients of the invention

• • when treating parts of plants, such as leaves, is as follows: from 0.1 to 10 000 g/ha, preferably from 10 to 1000 g/ha, more preferably from 50 to 300 g/ha (if applied by watering or dripping, the application rate may even be reduced, especially if inert substrates such as rock wool or perlite are used);
  • in the treatment of seed is as follows: from 2 to 200 g per 100 kg of seed, preferably from 3 to 150 g per 100 kg of seed, more preferably from 2.5 to 25 g per 100 kg of seed, very preferably from 2.5 to 12.5 g per 100 kg of seed;
  • for soil treatment is as follows: from 0.1 to 10 000 g/ha, preferably from 1 to 5000 g/ha.

These application rates are given only by way of example and without limitation for the purposes of the invention.

The active ingredients and/or compositions of the invention can therefore be used to protect plants, within a certain period of time after treatment, against infestation by animal pests, more particularly nematodes. The period of time within which protection of the plant is brought about extends in general over 1 to 28 days, preferably over 1 to 14 days, more preferably over 1 to 10 days, very preferably over 1 to 7 days after the treatment of the plants with the active ingredients, or to up to 200 days after seed treatment.

Foliar Applications

Foliar application is understood to mean the inventive treatment of the plants and plant parts with the active ingredients directly or by action on the environment, habitat or storage space thereof by the customary treatment methods, for example by dipping, spraying, vaporizing, nebulizing, scattering, painting and injecting. Plant parts are understood to mean all above-ground and below-ground parts and organs of the plants, such as shoot, leaf, flower and root, examples including leaves, needles, sterns, stalks, flowers, fruit-bodies, fruits and seeds, and also roots, tubers and rhizomes. The plant parts also include harvested plants and vegetative and generative propagation material, for example seedlings, tubers, rhizomes, runners and seeds.

Soil Application

Soil application is understood to mean the control of insects and/or spider mites and/or nematodes by drenching pesticides onto the soil, incorporating them into the soil and in irrigation systems as droplet application onto the soil. Alternatively, the inventive active ingredient combinations can be introduced into the site of the plants in solid form (for example in the form of granules), In the case of paddy rice crops, this may also be accomplished by metering the inventive active ingredient combinations in a solid application form (for example as a granule) into a flooded paddy field.

The invention relates to these application forms to natural (soil) or artificial substrates (for example rock wool, glass wool, quartz sand, pebbles, expanded clay, vermiculite), outdoors or in closed systems (e.g. greenhouses or under film cover) and in annual (e.g. vegetables, potatoes, cotton, beet, ornamental plants) or perennial crops (e.g. citrus plants, fruit, tropical crops, spices, nuts, vines, conifers and ornamental plants). It is additionally possible to deploy the active ingredients by the ultra-low-volume method or to inject the active ingredient formulation or the active ingredient itself into the soil.

Seed Treatment

The inventive active ingredient combinations are suitable especially for protection of seed of any plant variety which is used in agriculture, in greenhouses, in forests or in horticulture from the aforementioned animal pests, especially from nematodes. More particularly, the seed is that of cereals (such as wheat, barley, rye, millet and sorghum, and oats), maize, cotton, soya, rice, potatoes, sunflower, beans, coffee, beet (e.g. sugar beet and fodder beet), peanut, vegetables (such as tomato, cucumber, onions and lettuce), lawns and ornamental plants. Of particular significance is the treatment of the seed of cereals (such as wheat, barley, rye and oats), maize and rice, and the treatment of cotton and soya seed.

In the context of the present invention, the inventive composition is applied on its own or in a suitable formulation to the seed. Preferably, the seed is treated in a state in which it is sufficiently stable that the treatment does not cause any damage. In general, treatment of the seed may take place at any point in time between harvesting and sowing. Typically, the seed used has been separated :Aom the plant and freed from cobs, shells, stalks, coats, hairs or the flesh of the fruits. For example, it is possible to use seed which has been harvested, cleaned and dried to a moisture content of less than 15 wt %. Alternatively, it is also possible to use seed which, after drying, has been treated, for example, with water and then dried again.

When treating the seed, it generally has to be ensured that the amount of the inventive composition applied to the seed and/or the amount of further additives is selected such that the germination of the seed is not adversely affected, and that the resulting plant is not damaged. This must be borne in mind in particular in. the case of active ingredients which may exhibit phytotoxic effects at certain application rates.

The inventive active ingredient combinations/compositions can be applied directly, i.e. without comprising any further components and without having been diluted. In general, it is preferable to apply the compositions to the seed in the form of a suitable formulation. Suitable formulations and methods for the treatment of seed are known to the person skilled in the art and are described, for example, in the following documents: U.S. Pat. No. 4,272,417 A, U.S. Pat. No. 4,245,432 A, U.S. Pat. No. 4,808,430 A, U.S. Pat. No. 5,876,739 A, US 2003/0176428 A1. WO 2002/080675 A1, WO 2002/028186 A2.

The active ingredient combinations usable in accordance with the invention can be converted to the customary seed dressing product formulations such as solutions, emulsions, suspensions, powders, foams, slurries and other coating compositions for seed, and ULV formulations.

These formulations are prepared in the known manner by mixing the active ingredients or active ingredient combinations with customary additives, for example customary extenders and also solvents or diluents, dyes, wetters, dispersants, emulsifiers, antifoams, preservatives, secondary thickeners, adhesives, gibberellins, and also water.

The colorants which may be present in the seed dressing product formulations usable in accordance with the invention are all colorants which are customary for such purposes. Both pigments, which are sparingly soluble in water, and colorants, which are soluble in water, may be used. Examples of dyes include those known by the names Rhodamine 13, C.I. Pigment Red 112 and C.I. Solvent Red 1.

The wetters which may be present in the seed dressing product formulations usable in accordance with the invention are all substances which are conventionally used for the formulation of active agrochemical ingredients and for promoting wetting. Alkylnaphthalenesulfonates, such as diisopropyl- or ditsobutylnaphthalenesulfonates, can be used with preference.

Useful dispersants and/or emulsifiers which may be present in the seed dressing product formulations usable in accordance with the invention are all nonionic, anionic and cationic dispersants which are conventionally used for the formulation of active agrochemical ingredients. Nonionic or anionic dispersants or mixtures of nonionic or anionic dispersants can be used with preference. Suitable nonionic dispersants include, in particular, ethylene oxide/propylene oxide block polymers, alkylphenol polyglycol ethers and tristryrylphen.ol polyglycol ethers, and their phosphated or sulfated derivatives. Suitable anionic dispersants are, in particular, lignosulfonates, polyacrylic acid salts and arylsulfonate/formaldehyde condensates.

The antifoams which may be present in the seed dressing product formulations usable in accordance with the invention are all foam-suppressing substances conventionally used for the formulation of active agrochemical ingredients. Silicone antifoams and magnesium stearate can be used with preference.

The preservatives which may be present in the seed dressing product formulations usable in accordance with the invention are all substances which can be employed in agrochemical compositions for such purposes. Examples include dichlorophen and benzyl alcohol hemiformal.

The secondary thickeners which may be present in the seed dressing product formulations usable in accordance with the invention are all substances which can be employed in agrochemical compositions for such purposes. Cellulose derivatives, acrylic acid derivatives, xanthan, modified clays and finely divided silica are preferred.

The adhesives which may be present in the seed dressing product formulations usable in accordance with the invention are all customary binders which can be employed in seed dressing products. Preference is given to polyvinylpyrrolidone, polyvinyl acetate, polyvinyl alcohol and tylose.

The gibberellins which may be present in the seed dressing product formulations usable in accordance with the invention are preferably the gibberellins A1, A3 (=gibberellic acid), A4 and A7, particular preference being given to using gibberellic acid. The gibberellins are known (cf. R. Wegler “Chemie der Pflanzenschutz- and Schadlingsbekampfungsmittel” [Chemistry of Plant Protectants and Pesticides], Vol. 2, Springer Verlag, 1970, pp. 401-412).

The seed dressing product formulations usable in accordance with the invention can be employed either directly or after preceding dilution with water for the treatment of a wide range of seeds. For instance, the concentrates or the formulations obtainable therefrom by dilution with water can be used to dress the seed of cereals, such as wheat, barley, rye, oats and triticale, and the seed of maize, rice, rape, peas, beans, cotton, soya, sunflowers and beet, or else a wide variety of different vegetable seeds. The seed dressing product formulations usable in accordance with the invention or the dilute preparations thereof can also be used to dress seed of transgenic plants. In this context, additional synergistic effects may also occur as a consequence of the interaction with the substances formed by expression.

Useful apparatus which can be used to treat seed with the seed dressing product formulations usable in accordance with the invention, or with the preparations prepared therefrom by addition of water, is all mixing apparatus which can typically be used to dress seed. Specifically, the seed dressing procedure is to place the seed into a mixer, add the amount of seed dressing product formulation desired in each case, either as such or after preceding, dilution with water, and mix until the formulation has been distributed homogeneously on the seed. If appropriate, this is followed by a drying process.

The application rate of the seed dressing product formulations usable in accordance with the invention can be varied within a relatively wide range. It is guided by the particular content of the active ingredients in the formulations and by the seed. The application rates of the active ingredient combinations are generally between 0.001 and 50 g per kilogram of seed, preferably between 0.01 and 25 g per kilogram of seed.

Calculationmla for the mortality of a combination of two active ingredients

The anticipated effect of a given combination of two active ingredients may be calculated (ci Colby, S. R., “Calculating Synergistic and Antagonistic Responses of Herbicide Combinations”, Weeds 15, pages 20-22, 1967) as follows:

• • if
  • X is the mortality, expressed in % of the untreated control, when active ingredient is used in an application rate of m ppm, or m g/ha
  • Y is the mortality, expressed in % of the untreated control, when active ingredient B is used in an application rate of n ppm, or n g/ha
  • E is the mortality, expressed in % of the untreated control, when active ingredients A and B are used at application rates of m and n ppm or of m and n g/ha,
  • then

E = X + Y - X · Y 100 .

If the actual insecticide mortality is greater than calculated, then the combination is superadditive in its kill—that is, there is a synergistic effect. In this case the mortality actually observed must be greater than the value for the expected mortality IP calculated on the basis of the formula given above.

EXAMPLE 1

Myzus test (spray treatment)

Solvent: 78 parts by weight of acetone

• • 1.5 parts by weight of dimethylformamide

Emulsifier: 0.5 part by weight of alkylaryi polyglycol ether

A suitable preparation of active ingredient is prepared by mixing one part by weight of active ingredient with the stated amounts of solvent and emulsifier and diluting the concentrate with emulsifier-containing water to the desired concentration. A suitable suspension of biological agent is prepared by dissolving the cells, spores or viruses in emulsifier-containing water in the desired concentration.

Chinese cabbage (Brassica pekinensis) leaf disks infested by all stages of the green peach aphid (Myrus persicae) are sprayed with an active ingredient andlor biological agent preparation in the desired concentration.

After the desired time, the effect in % is ascertained. Here, 100% means that all of the aphids have been killed; 0% means that no aphids have been killed. The mortality figures determined are used for calculation according to the Colby formula (see sheet 1).

In this test, the following combination of fluopyram with a further active ingredient or with a biological agent in accordance with the present specification gave a synergistically boosted activity in comparison to the substances employed individually:

TABLE 1
Myzus persicae test

Active ingredient/biological	Concentration
agents	g ai/ha	Mortality in % after 1d

Fluopyram	1000	0
	500	0
Imicyafos	67.5	0
		found*	calc.**
Fluopyram + imicyafos	1000 + 67.5	100	0
Pyrethrum	100	80
		found*	calc.**
Fluopyram + pyrethrum	1000 + 100	100	80
Fluensulfone	2000	0
		found*	calc.**
Fluopyram + fluensulfone	500 + 2000	90	0
Paecilomyces lilacinus strain 251	5000	0
		found*	calc.**
Fluopyram + Paecilomyces lilacinus	1000 + 5000	70	0
strain 251
Bacillus amyloliquefaciens strain FZB 42	2000	0
		found*	calc.**
Fluopyram + Bacillus amyloliquefaciens	1000 + 2000	90	0
Cydia pomonella granulosis virus (CpGV)	1000	0
		found*	calc.**
Fluopyram + Cydia pomonella granulosis	1000 + 1000	70	0
virus (CpGV)

Active ingredient/biological	Concentration
agents	g ai/ha	Mortality in % after 6d

Fluopyram	1000	0
	500	0
Bacillus thuringiensis subsp. tenebrionis	1000	0
		found*	calc.**
Fluopyram. + Bacillus thuringiensis subsp.	1000 + 1000	80	0
tenebrionis
Azadirachtin	100	0
		found*	calc.**
Fluopyram + azadirachtin	1000 + 100	70	0
Metschnikowia fructicola	1000	0
		found*	calc.**
Fluopyram + Metschnikowia fructicola	500 + 3000	90	0
*found = insecticidal action found,
**calc. = action calculated by the Colby formula

EXAMPLE 2

Spodoptera frugiperda Test (Spray Treatment)

Solvent 78.0 parts by weight of acetone

• • 1.5 parts by weight of dimethylformamide

Emulsifier: 0.5 part by weight of alkylaryl polyglycol ether

A suitable preparation of active ingredient is prepared by mixing one part by weight of active ingredient with the stated amounts of solvent and emulsifier and diluting the concentrate with emulsifier-containing water to the desired concentration.

Maize (Zea mays; corn) leaf disks are sprayed with an active ingredient preparation of the desired concentration and, after drying off, are populated with caterpillars of the army worm (Spodoptera frugiperda).

After the desired time, the effect in % is ascertained. Here, 100% means that all of the caterpillars have been killed, 0% means that no caterpillar has been killed. The mortality figures determined are used for calculation according to the Colby formula (see sheet 1).

In this test, the following combination of fluopyram and a further active ingredient in accordance with the present specification gave a synergistically boosted activity in comparison to the active ingredients employed individually:

TABLE 2
Spodoptera frugiperda test

Active ingredient/biological	Concentration
agents	g ai/ha	Mortality in % after 2d

Fluopyram	1000	0
Pyrethrum	100	33
		found*	calc.**
Fluopyram + pyrethrum	1000 + 100	50	33
*found = insecticidal action found,
**calc. = action calculated by the Colby formula

EXAMPLE 3

Seed Treatment—Cotton Emergence Test

Seed of cotton :iossypium hirsutum) is mixed with the desired amount of active ingredient and spores and also water. After drying, 25 seed grains in each case are sown in pots filled with sandy loam.

After 2 days, the effect in % is ascertained on the basis of the cotton plants that have emerged.

The following combinations of fluopyram and biological agents gave a better emergence rate in comparison to the substances employed individually and to the untreated control:

TABLE 3
Cotton emergence

		Emergence in % in
Active ingredient/biological	Concentration	comparison to
agents	g ai/kg seed	untreated control

Control (untreated seed)		100
Fluopyram	1	133
	0.5	100
Bacillus subtilis strain GB 03	0.078	158
Fluopyram + B. subtilis	0.5 + 0.078	288
strain GB 03
Bacillus amyloliquefaciens	0.15	163
strain FZB 42	0.075	158
Fluopyram. + B. amyloliquefaciens	1.0 + 0.15	225
strain FZB 42	0.5 + 0.075	221
* found = insecticidal action found,
** calc. = action calculated by the Colby formula

EXAMPLE 4

Meloidogyne Incognita Test

Solvent: 125.0 parts by weight of acetone

A suitable preparation of active ingredient is prepared by mixing one part by weight of active ingredient with the stated amounts of solvent and diluting the concentrate with water to the desired concentration. A spore suspension is prepared by diluting the spores with water to the desired concentration.

Vessels are filled with sand, active ingredient solution, Meloidogyne incognita egg-and-larvae suspension, and lettuce seeds. The lettuce seeds germinate and the seedlings develop. The galls develop on the roots.

After the desired time, the nematicidal effect is determined on the basis of gall formation in %. Here, 100% means that no galls have been found; 0% means that the number of galls on the treated plants corresponds to the untreated control. The figures ascertained are used for calculation according to the Colby formula (see sheet 1).

In this test, the following combination of fluopyram and biological agents in accordance with the present specification gave a synergistically boosted activity in comparison to the active ingredients employed individually:

TABLE 4
Meloidogyne incognita test

Active ingredient/biological	Concentration
agents	in ppm	Mortality in % after 21d

Fluopyram	0.0005	0
Metarhizium anisopliae	5	0
strain F52
		found*	calc.**
Fluopyram + M. anisopliae	0.0005 + 5	80	0
strain F52
*found = insecticidal action found,
**calc. = action calculated by the Colby formula

EXAMPLE 5

Glycine max—Growth Promotion in Combination with Mycorrhiza

Seed of soya beans (Glycine max) is mixed with the desired amount of active ingredient in water. After drying, the seeds are sown in pots filled with sand and perlite (1:1). For inoculation with arbuscular mycorrhiza fungi, the sand-perlite mixture is mixed beforehand with the Mycorrhiza inoculum (AMykor GmbH; Germany) in a concentration of 25 ml/L. The seed is covered with 3 cm of Lecaton (expanded clay).

Over the following 44 days, the plants are cultivated in a greenhouse in good g-,to conditions. The pots are watered with nutrient solution (Hoagland and Artion, 1950, half-concentrated solution) with a low phosphate concentration (20 μM).

The untreated control plants are cultured without arbuscular mycorrhiza fungi, but under the same conditions.

The growth-promoting effect on shoot and roots is ascertained via the weight of the fresh roots of the treated plant in comparison to the untreated control.

The following combination of active ingredient and biological agents gives increased root growth in comparison to the ingredients and agents applied individually, and to the control:

TABLE 5
Plant growth of soya bean

		Root weight in % in
Active ingredient/biological	Concentration	comparison to
agents	mg/seed grain	untreated control

Control	—	100
Fluopyram	0.1	116.90
Arbuscular mycorrhiza fungus	—	133.21
Fluopyram + arbuscular	0.1	137.91
mycorrhiza fungus