Active matrix display device

A manufacturing method of an active matrix light emitting device in which the active matrix light emitting device can be manufactured in a shorter time with high yield at low cost compared with conventional ones will be provided. It is a feature of the present invention that a layered structure is employed for a metal electrode which is formed in contact with or is electrically connected to a semiconductor layer of each TFT arranged in a pixel area of an active matrix light emitting device. Further, the metal electrode is partially etched and used as a first electrode of a light emitting element. A buffer layer, a layer containing an organic compound, and a second electrode layer are stacked over the first electrode.

Surgical stapling apparatus

A surgical stapling apparatus is provided and includes a cartridge assembly defining a tissue contacting surface and a longitudinally extending elongate slot; an anvil assembly defining a tissue contacting surface and a longitudinally extending elongate slot; a surgical buttress releasably secured to at least one of the tissue contacting surface of the cartridge assembly and the tissue contacting surface of the anvil assembly by at least one anchor; a central knife blade slidably disposable in the longitudinal extending elongate slot of the cartridge assembly and the anvil assembly; and a knife blade supported in a distal end portion of at least one of the cartridge assembly and the anvil assembly, wherein the distal knife blade is actuatable by the central knife blade upon an actuation of the central knife blade.

Robotic instrument systems and methods utilizing optical fiber sensor

Robotic medical instrument systems and associated methods utilizing an optical fiber sensors such as Bragg sensor optical fibers. In one configuration, an optical fiber is coupled to an elongate instrument body and includes a fiber core having one or more Bragg gratings. A controller is configured to initiate various actions in response thereto. For example, a controller may generate and display a graphical representation of the instrument body and depict one or more position and/or orientation variables thereof, or adjust motors of an instrument driver to reposition the catheter or another instrument. Optical fibers having Bragg gratings may also be utilized with other system components including a plurality of working instruments that are positioned within a sheath lumen, an instrument driver, localization sensors, and/or an image capture device, and may also be coupled to a patient's body or associated structure that stabilizes the body.

Immunizing compositions comprising nucleic acids encoding the HIV-1 matrix protein myristate binding site

The present invention relates to an immunogenic composition. More particularly, the present invention is a composition directed to eliciting an immune response to at least one covalent binding site of myristate (SEQ ID NOS: 1-3) on the HIV matrix protein. The present invention contemplates three categories of embodiments: protein or protein fragments (SEQ ID NO: 1), messenger RNA, or DNA/RNA (SEQ ID NOS:2-3). DNA/RNA compositions may be either naked or recombinant. The present invention further contemplates use with a variety of immune stimulants.

Surgical method for stapling tissue

An exemplary method for surgically stapling tissue may include providing a surgical stapler that includes at least one staple, a pusher configured to hold at least one staple, a splay arm movable relative to the pusher, where that splay arm includes two spaced-apart splay tips, and a driver movable relative to the pusher; splaying at least one staple by plastically deforming the distalmost staple against the splay tips; and after splaying, closing at least one staple by plastically deforming the distalmost staple against the splay tips. Another exemplary method for surgically stapling tissue may include providing a surgical stapler comprising a plurality of staples, a pusher configured to hold the staples, a splay arm movable relative to the pusher, a driver movable relative to the pusher, wherein the pusher, splay arm and driver are initially in a first configuration relative to one another; splaying at least one staple to a splayed state; after splaying, closing at least one splayed staple, after which the pusher, splay arm and driver are in a second configuration relative to one another; and resetting the stapler to the first configuration of the pusher, splay arm and driver; where the splaying and closing each plastically deform at least one staple.

Analyte sensor

Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

Cordless power-assisted medical cauterization and cutting device

A cordless cautery and cutting surgical device includes a modular battery and a surgical handle operable to removably hold the battery thereto. The handle has a cordless radio-frequency-signal-generation assembly and a surgical bipolar end effector having jaws and a cutting blade therebetween. The signal-generation assembly selectively supplies radio-frequency signal to the end effector when powered for electrocautery of tissue between the jaws. The handle defines therein an aseptically sealable battery-holding compartment selectively exposed to the environment and removably holding therein the battery. A motor assembly is disposed in the handle and is electrically connected to the battery and/or the signal-generation assembly and is powered and controlled thereby. The motor assembly physically couples to the blade and/or at least one jaw for moving the blade/jaw(s). The second connector part electrically connects the battery to the signal-generation assembly and/or the motor assembly when the battery is removably disposed in the compartment.

Analyte sensor

Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

PROSTHETIC HEART VALVE FOR TRANSFEMORAL DELIVERY

Apparatus is provided that includes a valve prosthesis for attachment to a native valve complex of a subject. The prosthesis includes a support frame, which is shaped so as to define a plurality of axial support arches, which extend in a radially outward direction, and are configured to apply, regardless of a rotational orientation of the support frame with respect to the native valve complex, an upstream axial force to a downstream side of one or more native structures selected from the group consisting of: native leaflet tips of the native valve complex, and native valve commissures. The support frame is also shaped so as to define an upstream skirt, which is configured to apply a downstream axial force on an upstream side of the native valve complex. The prosthesis further includes a prosthetic heart valve, coupled to a portion of the support frame. Other embodiments are also described.

Cordless medical cauterization and cutting device

A cordless cautery and cutting surgical device includes a modular battery and a surgical handle. The battery has a cordless radio-frequency-signal-generation assembly generating an output radio-frequency signal and a first selectively removable connector part. The surgical handle has a first handle body portion with a bipolar cautery and cutting end effector. The end effector has jaws with bipolar contacts and a cutting blade disposed between the jaws. The handle has a second body portion connected to the first body portion, defines therein an aseptically sealable battery-holding compartment selectively exposed to the environment and removably holding therein the battery, and a second selectively removable connector part operable to removably hold the first connector part thereto. The second connector part has conductors electrically connecting the RF assembly to the bipolar contacts for supplying the radio-frequency signal to the bipolar contacts when the first and second connector parts are removably secured together.