Patent Applications published on Jul 1, 2010 - page 20

#5701 ✅ Patent 8,399,479 granted on 2013-03-19
US20100168158A1
Chemistry; metallurgy

Modulators of cystic fibrosis transmembrane conductance regulator

#5702 ✅ Patent 7,951,825 granted on 2011-05-31
US20100168159A1
Chemistry; metallurgy

Hetero compound

#5703 ✅ Patent 8,093,288 granted on 2012-01-10
US20100168160A1
Chemistry; metallurgy

Genipin derivatives and uses thereof

#5704
US20100168161A1
Chemistry; metallurgy

DERIVATIVES OF 4-(2-AMINO-1-HYDROXYETHYL)PHENOL AS AGONISTS OF THE BETA2 ADRENERGIC RECEPTOR

#5705
US20100168162A1
Human necessities

SELECTIVE INHIBITORS OF AKT AND METHODS OF USING SAME

#5706 ✅ Patent 8,088,795 granted on 2012-01-03
US20100168163A1
Chemistry; metallurgy

Cyclic-alkylamine derivatives as inhibitors of the interaction between MDM2 and p53

#5707 ✅ Patent 7,807,692 granted on 2010-10-05
US20100168164A1
Chemistry; metallurgy

Antidiabetic oxazolidinediones and thiazolidinediones

#5708
US20100168165A1
Human necessities

METHOD OF TREATING DISEASE INVOLVING MYELIN AND/OR AXONAL LOSS

#5709
US20100168166A1
Human necessities

Method of Providing An Antihistaminic Effect in a Hepatically Impaired Patient

#5710
US20100168167A1
Chemistry; metallurgy

Piperidinones Useful in the Treatment of Inflammation

#5711 ✅ Patent 7,998,981 granted on 2011-08-16
US20100168168A1
Chemistry; metallurgy

Aminoaryl sulphonamide derivatives as functional 5-HTligands

#5712 ✅ Patent 8,536,196 granted on 2013-09-17
US20100168169A1
Chemistry; metallurgy

Substituted 1,3-dioxanes useful as PPAR modulators

#5713
US20100168170A1
Chemistry; metallurgy

Piperidinones Useful in the Treatment of Inflammation

#5714
US20100168171A1
Chemistry; metallurgy

Piperidinone Carboxamide Derivatives as P2X7 Modulators

#5715 ✅ Patent 8,183,268 granted on 2012-05-22
US20100168172A1
Chemistry; metallurgy

Heteroaryl (substituted)alkyl -substituted sulfoximines as insecticides

#5716 ✅ Patent 8,158,657 granted on 2012-04-17
US20100168173A1
Human necessities

Heterocycles substituted pyridine derivatives and antifungal agent containing thereof

#5717
US20100168174A1
Human necessities

Combination of AMPA Receptor Antagonists and Acetylcholinesterase Inhibitors for the Treatment of Neuropathic Pain

#5718
US20100168175A1
Chemistry; metallurgy

ATPENINS

#5719
US20100168176A1
Chemistry; metallurgy

NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME

#5720
US20100168177A1
Human necessities

Stable insecticide compositions

#5721 ✅ Patent 8,507,532 granted on 2013-08-13
US20100168178A1
Human necessities

Stable insecticide compositions and methods for producing same

#5722
US20100168179A1
Chemistry; metallurgy

6-ALKENYL-, 6-ALKINYL- AND 6-EPOXY-EPOTHILONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION, AND THEIR USE IN PHARMACEUTICAL PREPARATIONS

#5723 ✅ Patent 8,236,827 granted on 2012-08-07
US20100168180A1
Chemistry; metallurgy

Compounds

#5724 ✅ Patent 7,956,190 granted on 2011-06-07
US20100168181A1
Chemistry; metallurgy

Benzimidazole amido derivatives as kinase inhibitors

#5725
US20100168182A1
Chemistry; metallurgy

COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS

#5726 ✅ Patent 8,039,492 granted on 2011-10-18
US20100168183A1
Chemistry; metallurgy

Substituted cyclic compound, its preparation process and its medical use

#5727 ✅ Patent 8,309,582 granted on 2012-11-13
US20100168184A1
Chemistry; metallurgy

Small molecule Bcl-Xl/Bcl-2 binding inhibitors

#5728 ✅ Patent 9,198,426 granted on 2015-12-01
US20100168185A1
Human necessities

Use of 5 pyridin-4-yl-1,3-thiazoles for controlling phytopathogenic fungi

#5729 ✅ Patent 8,466,178 granted on 2013-06-18
US20100168186A1
Human necessities

Pre-mixed, ready-to-use pharmaceutical compositions

#5730
US20100168187A1
Human necessities

THERAPEUTIC COMBINATION

#5731 ✅ Patent 7,923,568 granted on 2011-04-12
US20100168188A1
Chemistry; metallurgy

Estrogen receptor modulators

#5732 ✅ Patent 8,362,054 granted on 2013-01-29
US20100168189A1
Chemistry; metallurgy

Therapeutic substituted lactams

#5733 ✅ Patent 8,492,415 granted on 2013-07-23
US20100168190A1
Chemistry; metallurgy

Azoles and related derivatives as non-nucleoside reverse transcriptase inhibitors (NNRTIs) in antiviral therapy (HIV)

#5734
US20100168191A1
Human necessities

PHARMACEUTICAL FORMULATION COMPRISING PRAMIPEXOLE

#5735
US20100168192A1
Chemistry; metallurgy

BENZISOXAZOLE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS FOR THE TREATMENT OF E.G. RESPIRATORY DISEASES, EPILEPSY AND CONVULSIONS

#5736 ✅ Patent 8,455,526 granted on 2013-06-04
US20100168193A1
Chemistry; metallurgy

Therapeutic use of imidazole-5-carboxylic acid derivatives

#5737
US20100168194A1
Chemistry; metallurgy

Amino-5-[4-(difluoromethoxy)phenyl]-5-phenylimidazolone Compounds For The Inhibition Of Beta-secretase

#5738 ✅ Patent 8,470,863 granted on 2013-06-25
US20100168195A1
Chemistry; metallurgy

Derivatives and analogs of chroman as functionally selective ALPHA2C adrenoreceptor agonists

#5739 ✅ Patent 8,067,614 granted on 2011-11-29
US20100168196A1
Chemistry; metallurgy

N-substituted (benzoimidazol-2-yl)phenylamines, processes for their preparation, their use as a medicament or diagnostic aid, and a medicament comprising them

#5740
US20100168197A1
Chemistry; metallurgy

MUSCARINIC RECEPTOR ANTAGONISTS

#5741 ✅ Patent 8,470,861 granted on 2013-06-25
US20100168198A1
Chemistry; metallurgy

Mitochondria-targeted antioxidant prodrugs and methods of use

#5742 ✅ Patent 8,034,957 granted on 2011-10-11
US20100168199A1
Chemistry; metallurgy

Kinase inhibitors

#5743 ✅ Patent 9,480,678 granted on 2016-11-01
US20100168200A1
Human necessities

Antifungal pharmaceutical composition

#5744
US20100168201A1
Chemistry; metallurgy

Polymorphs of [R-(R*, R*) ]-2-(4-Fluorophenyl)-Beta, Delta-Dihydroxy-5-(1-Methylethyl)-3-Phenyl-4-[(Phenylamino)Carbonyl]-1H-Pyrrole-1-Heptanoic Acid Magnesium Salt (2:1)

#5745
US20100168202A1
Chemistry; metallurgy

RAD 9 AS A DIAGNOSTIC,PROGNOSTIC,AND THERAPEUTIC TOOL FOR PROSTATE CANCER

#5746 ✅ Patent 9,017,681 granted on 2015-04-28
US20100168203A1
Human necessities

Adenylyl cyclases as novel targets for antibactrial interventions

#5747 ✅ Patent 8,017,764 granted on 2011-09-13
US20100168204A1
Chemistry; metallurgy

Therapeutic uses of inhibitors of RTP801L

#5748
US20100168205A1
Chemistry; metallurgy

Methods and Compositions for Prevention or Treatment of RSV Infection Using Modified Duplex RNA Molecules

#5749 ✅ Patent 8,324,368 granted on 2012-12-04
US20100168206A1
Chemistry; metallurgy

GNAQ targeted dsRNA compositions and methods for inhibiting expression

#5750
US20100168207A1
Chemistry; metallurgy

COMPOSITIONS AND METHODS FOR SIRNA INHIBITION OF ANGIOGENESIS

#5751 ✅ Patent 8,017,765 granted on 2011-09-13
US20100168208A1
Human necessities

RNA interference mediated treatment of alzheimer's disease using short interfering nucleic acid (siNA)

#5752 ✅ Patent 8,299,044 granted on 2012-10-30
US20100168209A1
Human necessities

Apoptosis inducer for cancer cell

#5753
US20100168210A1
Human necessities

T-Cell Cytokine-Inducing Surface Molecules and Methods of Use

#5754 ✅ Patent 8,124,337 granted on 2012-02-28
US20100168211A1
Chemistry; metallurgy

Hereditary cataract status in canines based on HSF4 gene marker

#5755 ✅ Patent 8,084,601 granted on 2011-12-27
US20100168212A1
Chemistry; metallurgy

Oligomers

#5756 ✅ Patent 9,127,080 granted on 2015-09-08
US20100168213A1
Chemistry; metallurgy

Protein-coding RNA to correct mitochondrial dysfunction

#5757 ✅ Patent 7,960,527 granted on 2011-06-14
US20100168214A1
Chemistry; metallurgy

Nucleic acid and corresponding protein entitled 151P3D4 useful in treatment and detection of cancer

#5758
US20100168215A1
Chemistry; metallurgy

METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEUROLOGICAL DISEASE

#5759
US20100168216A1
Chemistry; metallurgy

PROSTAGLANDIN PHARMACEUTICAL COMPOSITIONS

#5760
US20100168217A1
Chemistry; metallurgy

SULFAMATOBENZOTHIOPHENE DERIVATIVES

#5761
US20100168218A1
Human necessities

METHOD OF REDUCING FOOD INTAKE

#5762
US20100168219A1
Human necessities

Chronic inflammation and transplantation

#5763
US20100168220A1
Human necessities

PLANT EXTRACT COMPOSITION FOR TREATING HEPATITIS C

#5764
US20100168221A1
Human necessities

PHARMACEUTICAL COMPOSITION FOR TREATING HEPATITIS B VIRUS AND HEALTH FOOD PRODUCT HAVING HEPATITIS B VIRUS INHIBITING EFFECTS

#5765 ✅ Patent 8,217,074 granted on 2012-07-10
US20100168222A1
Human necessities

Use of sargachromenol

#5766 ✅ Patent 8,110,555 granted on 2012-02-07
US20100168223A1
Human necessities

7-hydroxy chromones as potent antioxidants

#5767 ✅ Patent 8,198,320 granted on 2012-06-12
US20100168224A1
Human necessities

Hypoglycemic activity of osthole

#5768
US20100168225A1
Chemistry; metallurgy

Small-Molecule Hepatitis C Virus (HCV) NS3/4A Serine Protease Inhibitors

#5769 ✅ Patent 8,247,579 granted on 2012-08-21
US20100168226A1
Chemistry; metallurgy

Spirocyclic tetronic acid derivatives

#5770 ✅ Patent 8,158,165 granted on 2012-04-17
US20100168227A1
Human necessities

Preventative treatment and remission of allergic diseases

#5771
US20100168228A1
Human necessities

NOVEL CHEMOTHERAPEUTIC AGENTS AGAINST INFLAMMATION AND CANCER

#5772 ✅ Patent 8,415,508 granted on 2013-04-09
US20100168229A1
Human necessities

Process for the preparation of optically active compounds using transfer hydrogenation

#5773 ✅ Patent 8,258,180 granted on 2012-09-04
US20100168230A1
Chemistry; metallurgy

Methods for making organozinc salts and compositions containing the same

#5774
US20100168231A1
Chemistry; metallurgy

TARGET ENZYME FOR THE TREATMENT OF ACNE

#5775 ✅ Patent 8,389,759 granted on 2013-03-05
US20100168232A1
Chemistry; metallurgy

Oligomer-anticholinergic agent conjugates

#5776
US20100168233A1
Human necessities

TERBINAFINE FORMULATION

#5777 ✅ Patent 8,168,676 granted on 2012-05-01
US20100168234A1
Human necessities

Production on peracids using an enzyme having perhydrolysis activity

#5778 ✅ Patent 8,178,581 granted on 2012-05-15
US20100168235A1
Human necessities

Production of peracids using an enzyme having perhydrolysis activity

#5779 ✅ Patent 8,293,792 granted on 2012-10-23
US20100168236A1
Human necessities

Production of peracids using an enzyme having perhydrolysis activity

#5780 ✅ Patent 8,367,728 granted on 2013-02-05
US20100168237A1
Human necessities

Production of peracids using an enzyme having perhydrolysis activity

#5781 ✅ Patent 8,148,425 granted on 2012-04-03
US20100168238A1
Human necessities

Pharmaceutical composition containing phloroglucinol and paracetamol

#5782 ✅ Patent 8,809,310 granted on 2014-08-19
US20100168239A1
Human necessities

Use of rasagiline for the treatment of multiple system atrophy

#5783 ✅ Patent 7,985,876 granted on 2011-07-26
US20100168240A1
Chemistry; metallurgy

Substituted dibenzoic acid derivatives and use thereof

#5784
US20100168241A1
Human necessities

TREATMENT OF ACNE DISEASE STATES, NOTABLY ACNE VULGARIS

#5785 ✅ Patent 8,101,663 granted on 2012-01-24
US20100168242A1
Human necessities

Polymorphs of suberoylanilide hydroxamic acid

#5786
US20100168243A1
Chemistry; metallurgy

Renin Inhibitors

#5787 ✅ Patent 7,947,852 granted on 2011-05-24
US20100168244A1
Chemistry; metallurgy

Naphthalene compounds, a process for their preparation and pharmaceutical compositions containing them

#5788
US20100168245A1
Chemistry; metallurgy

PREPARATION OF (R,R)-FENOTEROL AND (R,R)-OR (R,S)-FENOTEROL ANALOGUES AND THEIR USE IN TREATING CONGESTIVE HEART FAILURE

#5789
US20100168246A1
Chemistry; metallurgy

AMINE COMPOUNDS AND INHIBITING NEUROTRANSMITTER REUPTAKE

#5790
US20100168247A1
Human necessities

SOLID COMPOSITES OF A CALCIUM RECEPTOR-ACTIVE COMPOUND

#5791 ✅ Patent 8,568,802 granted on 2013-10-29
US20100168248A1
Chemistry; metallurgy

Process for producing enriched fractions of tetrahydroxycurcumin and tetrahydrotetrahydroxy-curcumin from the extracts of

#5792
US20100168249A1
Human necessities

COMPOSITION CONTAINING REDUCED COENZYME Q10, AND METHOD FOR STABILIZING THE COMPOSITION

#5793
US20100168250A1
Human necessities

USE OF CYCLOHEXANEHEXOL DERIVATIVES IN THE TREATMENT OF OCULAR DISEASE

#5794 ✅ Patent 9,119,973 granted on 2015-09-01
US20100168251A1
Human necessities

Fragrance composition for core shell microcapsules

#5795
US20100168252A1
Chemistry; metallurgy

SUGAR DERIVATIVES, METHOD FOR PREPARATION THEREOF, THEIR USE AS SURFACE-ACTIVE AGENTS

#5796 ✅ Patent 8,507,564 granted on 2013-08-13
US20100168253A1
Chemistry; metallurgy

Method for selecting perfume ingredient, method for formulating fragrance, and preference-enhancing agent

#5797
US20100168254A1
Human necessities

HYDROGEL COMPOSITION FOR THE TREATMENT OF DERMATOLOGICAL DISORDERS

#5798
US20100168255A1
Chemistry; metallurgy

METHOD FOR PRODUCING A COMPOUND WHICH HAS AT LEAST ONE ETHER GROUP

#5799
US20100168256A1
Chemistry; metallurgy

USE OF PHOSPHORIC TRIAMIDES IN CLEANER AND HYGIENE APPLICATIONS

#5800
US20100168257A1
Performing operations; transporting

METAL-DOPED NICKEL OXIDES AS CATALYSTS FOR THE METHANATION OF CARBON MONOXIDE

#5801 ✅ Patent 8,263,523 granted on 2012-09-11
US20100168258A1
Performing operations; transporting

Preparation of cobalt-ruthenium/zeolite Fischer-Tropsch catalysts

#5802
US20100168259A1
Performing operations; transporting

PROMOTED CARBIDE-BASED FISCHER-TROPSCH CATALYST, METHOD FOR ITS PREPARATION AND USES THEREOF

#5803
US20100168260A1
Chemistry; metallurgy

POROUS MATERIALS AND PROCESS FOR THEIR PRODUCTION

#5804
US20100168261A1
Chemistry; metallurgy

FOAM AND FABRICATION METHOD THEREOF AND BUFFER MATERIALS COMPRISING THE SAME

#5805 ✅ Patent 8,242,184 granted on 2012-08-14
US20100168262A1
Chemistry; metallurgy

Process for producing flexible polyurethane foam

#5806
US20100168263A1
Chemistry; metallurgy

FLAME-RETARDED STYRENE-BASED RESIN COMPOSITIONS

#5807 ✅ Patent 8,865,786 granted on 2014-10-21
US20100168264A1
Physics

Antireflective coating compositions

#5808 ✅ Patent 8,735,534 granted on 2014-05-27
US20100168265A1
Chemistry; metallurgy

Precursor composition for polyimide and use thereof

#5809 ✅ Patent 8,252,879 granted on 2012-08-28
US20100168266A1
Physics

Photosensitive resin, method for preparing the resin, photosensitive resin composition and cured product of the resin composition

#5810 ✅ Patent 7,935,740 granted on 2011-05-03
US20100168267A1
Chemistry; metallurgy

Process for producing high melt strength polypropylene

#5811 ✅ Patent 7,906,562 granted on 2011-03-15
US20100168268A1
Chemistry; metallurgy

Epoxy resin, epoxy resin composition containing the epoxy resin as an essential component and a cured product containing the epoxy resin as an essential component

#5812
US20100168269A1
Chemistry; metallurgy

RADIATION AND CHEMICAL CURABLE COATING COMPOSITION

#5813
US20100168270A1
Chemistry; metallurgy

BIOCOMPATIBLE POLYCARBONATE AND RADIOPAQUE POLYMER COMPOSITIONS AND METHODS OF MANUFACTURING MEDICAL DEVICES WITH SAME

#5814 ✅ Patent 9,642,932 granted on 2017-05-09
US20100168271A1
Human necessities

Bone cement and methods of use thereof

#5815 ✅ Patent 8,304,494 granted on 2012-11-06
US20100168272A1
Chemistry; metallurgy

Polycarbonate resin composition with improved scratch resistance and melt flow index

#5816 ✅ Patent 7,947,127 granted on 2011-05-24
US20100168273A1
Chemistry; metallurgy

Cement retarder systems, and retarded cement compositions

#5817 ✅ Patent 8,808,445 granted on 2014-08-19
US20100168274A1
Chemistry; metallurgy

Asphalt-rubber compositions and systems and methods for preparing same

#5818
US20100168275A1
Performing operations; transporting

MICROCAPSULES, THEIR USE AND PROCESSES FOR THEIR MANUFACTURE

#5819 ✅ Patent 8,907,001 granted on 2014-12-09
US20100168276A1
Chemistry; metallurgy

Use of a pretreated precipitated silica as a reinforcing filler for silicon elastomer and the curable silicone elastomer compositions thus obtained by cold mixing

#5820 ✅ Patent 8,067,093 granted on 2011-11-29
US20100168277A1
Chemistry; metallurgy

Curing agents for epoxy-functional compounds

#5821 ✅ Patent 8,304,034 granted on 2012-11-06
US20100168278A1
Chemistry; metallurgy

One-solution type thermosetting composition for protective film of color filter, and color filter using same

#5822
US20100168279A1
Chemistry; metallurgy

THERMALLY CURABLE EPOXY-AMINE BARRIER SEALANTS

#5823 ✅ Patent 8,273,806 granted on 2012-09-25
US20100168280A1
Chemistry; metallurgy

Process for preparing a self-healing composite material

#5824
US20100168281A1
Chemistry; metallurgy

Spalling-Preventing Composite Material Composed of Fiber and Powder Having Different Diameters and Melting Points, and High-Strength Refractory Concrete Comprising the Same

#5825
US20100168282A1
Chemistry; metallurgy

DISPERSION COMPRISING INORGANIC PARTICLES, WATER, AND AT LEAST ONE POLYMERIC ADDITIVE

#5826 ✅ Patent 7,915,328 granted on 2011-03-29
US20100168283A1
Chemistry; metallurgy

Flame retardant resinous compositions and process

#5827 ✅ Patent 7,915,329 granted on 2011-03-29
US20100168284A1
Chemistry; metallurgy

Flame retardant resinous compositions and process

#5828
US20100168285A1
Chemistry; metallurgy

Diethylene tricarbamide and diethylene tricarbamide-formaldehyde condensation resins

#5829
US20100168286A1
Textiles; paper

NONWOVEN PANEL AND METHOD OF CONSTRUCTION THEREOF

#5830 ✅ Patent 9,314,947 granted on 2016-04-19
US20100168287A1
Chemistry; metallurgy

Adhesives, reaction systems, and processes for production of lignocellulosic composites

#5831 ✅ Patent 8,314,166 granted on 2012-11-20
US20100168288A1
Fixed constructions

Waterproof sheet

#5832 ✅ Patent 7,829,614 granted on 2010-11-09
US20100168289A1
Chemistry; metallurgy

Reinforced polyester compositions, methods of manufacture, and articles thereof

#5833 ✅ Patent 8,138,244 granted on 2012-03-20
US20100168290A1
Chemistry; metallurgy

Reinforced polyester compositions, method of manufacture, and articles thereof

#5834 ✅ Patent 8,013,045 granted on 2011-09-06
US20100168291A1
Chemistry; metallurgy

Monoazo colorants for mass-colouring of polymers

#5835 ✅ Patent 8,119,720 granted on 2012-02-21
US20100168292A1
Chemistry; metallurgy

Thermoplastic resin composition having improved flowability

#5836 ✅ Patent 7,858,680 granted on 2010-12-28
US20100168293A1
Chemistry; metallurgy

Thermoplastic polycarbonate compositions

#5837 ✅ Patent 8,048,945 granted on 2011-11-01
US20100168294A1
Chemistry; metallurgy

4,4′-biphenol polysulfone compositions, process to prepare them, and articles made thereof

#5838
US20100168295A1
Chemistry; metallurgy

Polycarbonate Flame Retardant Compositions

#5839 ✅ Patent 8,008,382 granted on 2011-08-30
US20100168296A1
Chemistry; metallurgy

Flameproof thermoplastic resin composition

#5840
US20100168297A1
Chemistry; metallurgy

HIGH-GLOSS POLYURETHANE COATINGS PREPARED FROM ALLOPHANATE/POLYISOCYANATE HARDENER COMPOSITIONS

#5841 ✅ Patent 8,058,356 granted on 2011-11-15
US20100168298A1
Chemistry; metallurgy

Method for manufacturing hydrogenated block copolymer

#5842
US20100168299A1
Textiles; paper

Flame-Retardant Polyester Fibers and Preparation Process Thereof

#5843 ✅ Patent 8,338,517 granted on 2012-12-25
US20100168300A1
Chemistry; metallurgy

Aqueous compositions of fluorinated surfactants and methods of using the same

#5844
US20100168301A1
Chemistry; metallurgy

AQUEOUS FLUORINE-CONTAINING POLYMER DISPERSION AND METHOD FOR PRODUCTION THEREOF

#5845 ✅ Patent 8,153,712 granted on 2012-04-10
US20100168302A1
Chemistry; metallurgy

Crosslinkable rubber composition and cross-linked rubber

#5846 ✅ Patent 8,916,633 granted on 2014-12-23
US20100168303A1
Electricity

TAB leader tape made of polyphenylene ether-based resin

#5847 ✅ Patent 9,175,177 granted on 2015-11-03
US20100168304A1
Chemistry; metallurgy

Coating composition

#5848 ✅ Patent 8,075,862 granted on 2011-12-13
US20100168305A1
Chemistry; metallurgy

Hydrophobic fumed silica and silicone rubber materials containing the fumed silica

#5849
US20100168306A1
Performing operations; transporting

Rubber Composition Exhibiting Improved Adhesion to a Metal Reinforcement

#5850 ✅ Patent 8,247,075 granted on 2012-08-21
US20100168307A1
Chemistry; metallurgy

Modified perovskite complex oxide, method for producing the same and composite dielectric material

#5851 ✅ Patent 8,084,528 granted on 2011-12-27
US20100168308A1
Chemistry; metallurgy

Heat-resistant paint

#5852 ✅ Patent 8,592,545 granted on 2013-11-26
US20100168309A1
Chemistry; metallurgy

Polymer and polymer compositions

#5853 ✅ Patent 7,754,789 granted on 2010-07-13
US20100168310A1
Chemistry; metallurgy

Method for forming flame-retardant clay-polyolefin composites

#5854 ✅ Patent 7,999,037 granted on 2011-08-16
US20100168311A1
Chemistry; metallurgy

Polycarbonate compositions

#5855
US20100168312A1
Performing operations; transporting

Rubber Composition for Tread

#5856 ✅ Patent 8,178,207 granted on 2012-05-15
US20100168313A1
Chemistry; metallurgy

Silicone-based pressure-sensitive adhesive composition and adhesive tape

#5857
US20100168314A1
Chemistry; metallurgy

THERMOPLASTIC COMPOSITION WITH IMPROVED LOW TEMPERATURE DUCTILITY

#5858 ✅ Patent 8,389,628 granted on 2013-03-05
US20100168315A1
Chemistry; metallurgy

High flow thermoplastic resin composition with excellent chemical resistance, impact resistance and gloss

#5859 ✅ Patent 8,871,856 granted on 2014-10-28
US20100168316A1
Chemistry; metallurgy

Wetting agents and dispersants based on mixtures of structure copolymers

#5860
US20100168317A1
Chemistry; metallurgy

POLY(BUTYLENE TEREPHTHALATE) COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF

#5861 ✅ Patent 8,916,058 granted on 2014-12-23
US20100168318A1
Chemistry; metallurgy

Fluorobetaine copolymer and fire fighting foam concentrates therefrom

#5862 ✅ Patent 8,193,276 granted on 2012-06-05
US20100168319A1
Chemistry; metallurgy

Fluorocopolymer and water and oil proofing composition, and processes for their production

#5863 ✅ Patent 8,193,279 granted on 2012-06-05
US20100168320A1
Chemistry; metallurgy

Flexible, radiation-curable coating compositions

#5864
US20100168321A1
Chemistry; metallurgy

POLY(BUTYLENE TEREPHTHALATE) COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF

#5865
US20100168322A1
Chemistry; metallurgy

INKJET RECORDING LIQUID

#5866 ✅ Patent 8,324,335 granted on 2012-12-04
US20100168323A1
Chemistry; metallurgy

Propylene-based polymer and method for producing the same, and propylene-based resin composition

#5867 ✅ Patent 8,481,638 granted on 2013-07-09
US20100168324A1
Chemistry; metallurgy

High temperature PP adhesive

#5868 ✅ Patent 8,481,640 granted on 2013-07-09
US20100168325A1
Chemistry; metallurgy

Polymer compositions

#5869 ✅ Patent 8,338,528 granted on 2012-12-25
US20100168326A1
Chemistry; metallurgy

RTV two-component silicone rubber

#5870 ✅ Patent 8,404,786 granted on 2013-03-26
US20100168327A1
Chemistry; metallurgy

Polymer and process for producing the same, composition for forming insulating film, and insulating film and method of forming the same

#5871
US20100168328A1
Chemistry; metallurgy

PROCESS FOR THE MANUFACTURE OF POLYCYCLOHEXANE DIMETHYLENE TEREPHTHALATE COPOLYMERS FROM POLYETHYLENE TEREPHTHALATE, AND COMPOSITIONS AND ARTICLES THEREOF

#5872
US20100168329A1
Chemistry; metallurgy

ALIPHATIC, CYCLOALIPHATIC OR (CYCLO)ALIPHATIC DIISOCYANATES THAT ARE STABLE IN STORAGE

#5873 ✅ Patent 8,202,958 granted on 2012-06-19
US20100168330A1
Chemistry; metallurgy

Long chain branched (LCB), block or interconnected copolymers of ethylene in combination with one other polymer

#5874 ✅ Patent 8,247,478 granted on 2012-08-21
US20100168331A1
Chemistry; metallurgy

Thermoplastic resin composition

#5875
US20100168332A1
Chemistry; metallurgy

Polylactic Acid Resin Composition and Molded Product Using the Same

#5876
US20100168333A1
Chemistry; metallurgy

Thermoplastic Resin Having Excellent Heat Resistance and Impact Strength and Method of Preparing the Same

#5877
US20100168334A1
Chemistry; metallurgy

Polymeric Compositions and Polymerization Initiators Using Photo-Peroxidation Process

#5878
US20100168335A1
Chemistry; metallurgy

METHOD FOR PRODUCING POLYMER MIXTURES

#5879 ✅ Patent 7,910,657 granted on 2011-03-22
US20100168336A1
Chemistry; metallurgy

Process for the manufacture of polybutylene terephthalate copolymers from polyethylene terephthalate, and compositions and articles thereof

#5880 ✅ Patent 8,440,387 granted on 2013-05-14
US20100168337A1
Physics

Graded topcoat materials for immersion lithography

#5881
US20100168338A1
Chemistry; metallurgy

METHOD FOR PREPARING A POLYMERIC MATERIAL INCLUDING A MULTIBLOCK COPOLYMER PREPARED BY CONTROLLED FREE-RADICAL POLYMERISATION

#5882
US20100168339A1
Chemistry; metallurgy

NOVEL METHODS FOR FORMING COPOLYMERS COMPRISING OLEFIN AND PROTECTED OR UNPROTECTED HYDROXYSTYRENE UNITS

#5883 ✅ Patent 7,972,680 granted on 2011-07-05
US20100168340A1
Chemistry; metallurgy

Resin composition and film

#5884 ✅ Patent 8,138,284 granted on 2012-03-20
US20100168341A1
Chemistry; metallurgy

Process for producing propylene block copolymer

#5885 ✅ Patent 7,935,766 granted on 2011-05-03
US20100168342A1
Chemistry; metallurgy

Propylene impact copolymer and method

#5886 ✅ Patent 9,000,099 granted on 2015-04-07
US20100168343A1
Chemistry; metallurgy

Functionalized polymers, articles prepared therefrom, and methods for making the same

#5887
US20100168344A1
Chemistry; metallurgy

POLYESTER BASED BLEND AND PACKAGING ARTICLE MADE THEREFROM

#5888 ✅ Patent 7,919,640 granted on 2011-04-05
US20100168345A1
Chemistry; metallurgy

Synthesis with metal methacrylates as comonomers

#5889
US20100168346A1
Chemistry; metallurgy

Sulfonated Poly (Arylene Ether) Containing Crosslinkable Moiety at End Group, Method of Manufacturing the Same, and Polymer Electrolyte Membrane Using the Sulfonated Poly (Arylene Ether) and the Method

#5890 ✅ Patent 7,956,157 granted on 2011-06-07
US20100168347A1
Chemistry; metallurgy

Processes using dividing wall distillation column

#5891
US20100168348A1
Chemistry; metallurgy

ANIONIC SPRAY POLYMERIZATION OF STYRENE

#5892
US20100168349A1
Chemistry; metallurgy

PROCESS FOR PRODUCING ALPHA-OLEFIN POLYMERIZATION CATALYST

#5893 ✅ Patent 9,200,094 granted on 2015-12-01
US20100168350A1
Chemistry; metallurgy

Catalyst components for the polymerization of olefins

#5894 ✅ Patent 8,420,563 granted on 2013-04-16
US20100168351A1
Performing operations; transporting

Catalyst complex and process for producing multimodal molecular weight polyolefins

#5895 ✅ Patent 7,956,132 granted on 2011-06-07
US20100168352A1
Chemistry; metallurgy

Production of telechelic compounds by metathesis depolymerization

#5896 ✅ Patent 8,263,692 granted on 2012-09-11
US20100168353A1
Chemistry; metallurgy

Propylene-based polymer, articles, and process for producing same

#5897 ✅ Patent 8,097,680 granted on 2012-01-17
US20100168354A1
Chemistry; metallurgy

Low gloss thermoplastic resin having excellent heat resistance and impact strength and method of preparing the same

#5898 ✅ Patent 8,076,435 granted on 2011-12-13
US20100168355A1
Chemistry; metallurgy

Acrylic copolymers with high heat-resistance and preparation thereof

#5899
US20100168356A1
Human necessities

Biomedical Devices

#5900
US20100168357A1
Chemistry; metallurgy

Branched Ionomers with Metal Methacrylates as Comonomers

#5901 ✅ Patent 8,324,331 granted on 2012-12-04
US20100168358A1
Chemistry; metallurgy

Fluorine-containing compound and polymeric compound

#5902 ✅ Patent 8,324,256 granted on 2012-12-04
US20100168359A1
Chemistry; metallurgy

Tri-functional UV-absorbing compounds and use thereof

#5903 ✅ Patent 8,252,869 granted on 2012-08-28
US20100168360A1
Electricity

Process for production of crosslinked poly(meth) acrylic acid nitroxide compounds

#5904 ✅ Patent 8,101,700 granted on 2012-01-24
US20100168361A1
Chemistry; metallurgy

Phosphonic polymers having a phosphinate backbone and methods of making and using thereof

#5905
US20100168362A1
Chemistry; metallurgy

Vinyl acetate / butenedioic acid cycloalkyl ester copolymers and uses thereof

#5906
US20100168363A1
Chemistry; metallurgy

Low Birefringent Copolymers

#5907 ✅ Patent 8,153,745 granted on 2012-04-10
US20100168364A1
Chemistry; metallurgy

Multi-branched polypropylene

#5908
US20100168365A1
Chemistry; metallurgy

Production Process of Glucan Derivative Modified With Cyclic Ester

#5909 ✅ Patent 8,450,441 granted on 2013-05-28
US20100168366A1
Chemistry; metallurgy

Synthetic N-linked sialo-glycan-containing polymer and method for producing the same

#5910 ✅ Patent 8,309,673 granted on 2012-11-13
US20100168367A1
Chemistry; metallurgy

Polyether siloxane-containing alkoxylation products by direct alkoxylation of organomodified α,ω-dihydroxysiloxanes over double metal cyanide (DMC) catalysts, and also process for producing them

#5911
US20100168368A1
Chemistry; metallurgy

Epoxy Resin, Method for Producing Same and Epoxy Resin Composition Thereof

#5912 ✅ Patent 7,999,058 granted on 2011-08-16
US20100168369A1
Chemistry; metallurgy

Method for producing aromatic polymer

#5913 ✅ Patent 7,848,025 granted on 2010-12-07
US20100168370A1
Chemistry; metallurgy

Transparent articles prepared from thermoplastic compositions having high flow and ductility, and method of preparing articles

#5914
US20100168371A1
Chemistry; metallurgy

Bio-Based Terephthalate Polyesters

#5915 ✅ Patent 8,946,472 granted on 2015-02-03
US20100168372A1
Chemistry; metallurgy

Bio-based terephthalate polyesters

#5916
US20100168373A1
Chemistry; metallurgy

Bio-Based Terephthalate Polyesters

#5917 ✅ Patent 7,790,836 granted on 2010-09-07
US20100168374A1
Chemistry; metallurgy

Diamine compound having dendron side chain and liquid crystal aligning agent using same

#5918 ✅ Patent 8,772,439 granted on 2014-07-08
US20100168375A1
Chemistry; metallurgy

Production of solutions of diacid/diamine salts

#5919 ✅ Patent 8,026,337 granted on 2011-09-27
US20100168376A1
Textiles; paper

Production of a functionalized polytriazole polymer

#5920
US20100168377A1
Chemistry; metallurgy

Catalytic conversion of amide compounds to methyl ether polymers and methyl ether ladder polymers

#5921 ✅ Patent 8,188,195 granted on 2012-05-29
US20100168378A1
Chemistry; metallurgy

Polymers functionalized with nitroso compounds

#5922 ✅ Patent 8,399,692 granted on 2013-03-19
US20100168379A1
Chemistry; metallurgy

Epichlorohydrin, manufacturing process and use

#5923 ✅ Patent 9,090,668 granted on 2015-07-28
US20100168380A1
Chemistry; metallurgy

Process for synthesizing cyclic peptide compound

#5924 ✅ Patent 8,017,727 granted on 2011-09-13
US20100168381A1
Chemistry; metallurgy

Conjugates of membrane translocating agents and pharmaceutically active agents

#5925
US20100168382A1
Human necessities

NEUROPLASTIN DERIVED PEPTIDES

#5926 ✅ Patent 8,546,528 granted on 2013-10-01
US20100168383A1
Chemistry; metallurgy

Skin or hair binding peptides

#5927 ✅ Patent 8,232,246 granted on 2012-07-31
US20100168384A1
Chemistry; metallurgy

Anti-viral compounds

#5928
US20100168385A1
Chemistry; metallurgy

PROCESS FOR PREPARING ENANTIOMERICALLY ENRICHED AMINO-ALCOHOLS

#5929
US20100168386A1
Chemistry; metallurgy

FUSION PROTEIN CARRYING NEUROTROPHIN ACROSS THE BLOOD-BRAIN BARRIER, ENCODING GENE AND USES THEREOF

#5930
US20100168387A1
Chemistry; metallurgy

Chimeric CrylE Delta Endotoxin and Methods of Controlling Insects

#5931 ✅ Patent 8,889,632 granted on 2014-11-18
US20100168388A1
Chemistry; metallurgy

Stabilized p53 peptides and uses thereof

#5932
US20100168389A1
Chemistry; metallurgy

PROCESS FOR PRODUCING EXTRACT FOR CELL-FREE PROTEIN SYNTHESIS AND CELL EXTRACT PRODUCED THEREBY

#5933 ✅ Patent 10,030,065 granted on 2018-07-24
US20100168390A1
Chemistry; metallurgy

MHC multimers, methods for their generation, labeling and use

#5934 ✅ Patent 8,053,561 granted on 2011-11-08
US20100168391A1
Chemistry; metallurgy

Pegylated factor VIII

#5935
US20100168392A1
Chemistry; metallurgy

EXPRESSION OF FULL LENGTH IGG AND SECRETION INTO THE CULTURE MEDIUM OF PROKARYOTIC CELLS

#5936
US20100168393A1
Chemistry; metallurgy

Antibody Polypeptide Libray Screening and Selected Antibody Polypeptides

#5937 ✅ Patent 8,026,343 granted on 2011-09-27
US20100168394A1
Chemistry; metallurgy

Antibody modulating the differentiation and function of dendritic cells via binding intercellular adhesion molecule-1 and use thereof

#5938 ✅ Patent 8,198,409 granted on 2012-06-12
US20100168395A1
Chemistry; metallurgy

Polypeptide, an affinity chromatography material, and a method for separating and/or purifying immunoglobulin

#5939 ✅ Patent 8,680,235 granted on 2014-03-25
US20100168396A1
Chemistry; metallurgy

Branchiostoma derived fluorescent proteins

#5940 ✅ Patent 8,008,450 granted on 2011-08-30
US20100168397A1
Chemistry; metallurgy

Therapeutic use of anti-CS1 antibodies

#5941
US20100168398A1
Physics

Method, computing routine, device for predicting properties of MHC/peptide complexes, and data and peptides produced therefrom.

#5942 ✅ Patent 7,939,640 granted on 2011-05-10
US20100168399A1
Chemistry; metallurgy

Antibodies that bind B7L-1

#5943 ✅ Patent 7,939,638 granted on 2011-05-10
US20100168400A1
Chemistry; metallurgy

Superagonistic anti-CD28 antibodies

#5944
US20100168401A1
Human necessities

Method, composition and kit for detecting phosphatidylserine (PS) on cell membranes

#5945
US20100168402A1
Chemistry; metallurgy

Direct Attachment of Polypeptides to Virus Like Particles

#5946
US20100168403A1
Chemistry; metallurgy

Protein refolding agent and refolding method

#5947 ✅ Patent 8,362,220 granted on 2013-01-29
US20100168404A1
Electricity

Metal complex compositions and methods for making metal-containing films

#5948
US20100168405A1
Chemistry; metallurgy

ACTIVATOR INCLUDING BIOSURFACTANT AS ACTIVE INGREDIENT, MANNOSYL ERYTHRITOL LIPID, AND PRODUCTION METHOD THEREOF

#5949
US20100168406A1
Human necessities

USE OF GINSENOSIDE Rb2 MONOMER IN THE MANUFACTURE OF MEDICAMENTS FOR THROMBOLYSIS

#5950
US20100168407A1
Human necessities

Quaternized Carboxymethyl Chitosan Derivatives and Preparation Method Thereof

#5951
US20100168408A1
Chemistry; metallurgy

COMPOSITIONS AND METHODS FOR LABELING OF NUCLEIC ACID MOLECULES

#5952
US20100168409A1
Performing operations; transporting

THERMOPLASTIC RESIN FILM AND METHOD FOR PRODUCING SAME

#5953
US20100168410A1
Human necessities

Hydroxypropyl Methyl Cellulose Hard Capsules and Process of Manufacture

#5954
US20100168411A1
Chemistry; metallurgy

Method of producing fermentation product and fermentation product

#5955
US20100168412A1
Chemistry; metallurgy

Continuous Neutralizer Mixer Reactor and a Continuous Process for Quenching Chlorination Reaction Mixture in Production of Chlorinated Sucrose

#5956 ✅ Patent 7,947,844 granted on 2011-05-24
US20100168413A1
Chemistry; metallurgy

One-pot synthesis of benzisoindolenines used in the preparation of naphthalocyanines

#5957
US20100168414A1
Chemistry; metallurgy

PROCESSES FOR PREPARING EZETIMIBE AND INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION THEREOF

#5958
US20100168415A1
Chemistry; metallurgy

Process for preparation of Caspofungin acetate

#5959 ✅ Patent 8,618,331 granted on 2013-12-31
US20100168416A1
Chemistry; metallurgy

Polycyclic heteroaryl substituted triazoles useful as axl inhibitors

#5960 ✅ Patent 8,148,392 granted on 2012-04-03
US20100168417A1
Chemistry; metallurgy

2-indolyl imidazo [4,5-d] phenanthroline derivatives and their use in the treatment of cancer

#5961 ✅ Patent 8,329,694 granted on 2012-12-11
US20100168418A1
Chemistry; metallurgy

Quinoxalinones as antibacterial composition

#5962
US20100168419A1
Chemistry; metallurgy

Diacylglycerol Acyltransferase Inhibitors

#5963 ✅ Patent 8,362,240 granted on 2013-01-29
US20100168420A1
Chemistry; metallurgy

Taxol derivatives with antitumor activity

#5964
US20100168421A1
Chemistry; metallurgy

A NEW PEPTIDE DEFORMYLASE INHIBITOR COMPOUND AND MANUFACTURING PROCESS THEREOF

#5965
US20100168422A1
Chemistry; metallurgy

METHODS AND INTERMEDIATES USEFUL IN THE SYNTHESIS OF HEXAHYDROFURO [2,3-B]FURAN-3-OL

#5966
US20100168423A1
Chemistry; metallurgy

METHOD FOR THE PRODUCTION OF BRIDGED DIBENZ[c,e] [1,2]-OXAPHOSPHORIN-6-OXIDES

#5967
US20100168424A1
Chemistry; metallurgy

FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF

#5968 ✅ Patent 8,569,489 granted on 2013-10-29
US20100168425A1
Chemistry; metallurgy

7-[4-(Benzhydrylpiperazinyl-1)butyl]-3-methylxanthine and its salts with organic or inorganic acids possessing antihistaminic and antiallergenic activity

#5969
US20100168426A1
Chemistry; metallurgy

NOVEL PROCESSES FOR THE PRODUCTION OF USEFUL INTERMEDIATES

#5970 ✅ Patent 8,318,936 granted on 2012-11-27
US20100168427A1
Chemistry; metallurgy

Method for producing N-methylnaltrexone bromide

#5971 ✅ Patent 8,440,835 granted on 2013-05-14
US20100168428A1
Chemistry; metallurgy

Environmentally sensitive fluorophores

#5972 ✅ Patent 8,026,375 granted on 2011-09-27
US20100168429A1
Chemistry; metallurgy

Transition metal catalyzed synthesis of N-aminoindoles

#5973 ✅ Patent 8,299,252 granted on 2012-10-30
US20100168430A1
Chemistry; metallurgy

Pyrazolopyridine and pyrrolopyridine multikinase inhibitors

#5974 ✅ Patent 8,357,807 granted on 2013-01-22
US20100168431A1
Chemistry; metallurgy

Isoquinolinium compounds useful in the preparation of cisatracurium and associated intermediates

#5975
US20100168432A1
Chemistry; metallurgy

Process for the Preparation of Montelukast

#5976
US20100168433A1
Chemistry; metallurgy

PROCESS FOR PREPARING BEPOTASTINE AND INTERMEDIATES USED THEREIN

#5977
US20100168434A1
Chemistry; metallurgy

INHIBITION OF POLYMERISATION

#5978 ✅ Patent 8,318,946 granted on 2012-11-27
US20100168435A1
Chemistry; metallurgy

Process for the preparation of 2-substituted-5-(1-alkylthio)alkylpyridines

#5979 ✅ Patent 8,129,539 granted on 2012-03-06
US20100168436A1
Chemistry; metallurgy

Process for the preparation of 2-substituted-5-(1-alkylthio)alkylpyridines

#5980
US20100168437A1
Chemistry; metallurgy

PROCESS FOR THE PREPARATION OF 2-SUBSTITUTED-5-(1-ALKYLTHIO)ALKYLPYRIDINES

#5981 ✅ Patent 8,119,830 granted on 2012-02-21
US20100168438A1
Human necessities

Dual function UV-absorbers for ophthalmic lens materials

#5982 ✅ Patent 8,507,778 granted on 2013-08-13
US20100168439A1
Physics

Self-assembled polyhedra

#5983 ✅ Patent 8,481,791 granted on 2013-07-09
US20100168440A1
Chemistry; metallurgy

Homogeneous asymmetric hydrogenation process

#5984
US20100168441A1
Chemistry; metallurgy

PROCESS FOR PRODUCTION OF SUBSTITUTED BENZENE

#5985 ✅ Patent 8,088,932 granted on 2012-01-03
US20100168442A1
Chemistry; metallurgy

Pentaaryldiamine-containing bismaleimide compound and method of producing the compound

#5986
US20100168443A1
Human necessities

Ethoid-Containing Compounds, Methods for Preparing Ethoid-Containing Compounds, and Methods of Use

#5987 ✅ Patent 8,236,967 granted on 2012-08-07
US20100168444A1
Chemistry; metallurgy

Diindenothiophene derivatives and use thereof

#5988
US20100168445A1
Chemistry; metallurgy

PROCESS FOR PREPARING EPSILON-CAPROLACTONE

#5989 ✅ Patent 8,404,868 granted on 2013-03-26
US20100168446A1
Chemistry; metallurgy

Method for purification of cyclic ester

#5990 ✅ Patent 8,765,975 granted on 2014-07-01
US20100168447A1
Chemistry; metallurgy

Production of dihydronepetalactone

#5991 ✅ Patent 8,846,409 granted on 2014-09-30
US20100168448A1
Performing operations; transporting

Methods of preparing cannabinoids from plant material

#5992
US20100168449A1
Performing operations; transporting

Spray dried zeolite catalyst

#5993
US20100168450A1
Chemistry; metallurgy

NOVEL BRANCHED ALKOXYLATES

#5994
US20100168451A1
Human necessities

PREPARATIVE METHOD OF DIHYDROCUCURBITACIN F-25-O-ACETATE AND THE USE THEREOF IN THE MANUFACTURE OF MEDICAMENTS FOR TREATING CANCERS

#5995 ✅ Patent 8,558,062 granted on 2013-10-15
US20100168452A1
Human necessities

High oleic imidazolinone resistant sunflower

#5996 ✅ Patent 8,642,792 granted on 2014-02-04
US20100168453A1
Chemistry; metallurgy

Method for the synthesis of omega-amino-alkanoic acids

#5997 ✅ Patent 8,242,318 granted on 2012-08-14
US20100168454A1
Chemistry; metallurgy

Catalytic hydrogenation

#5998
US20100168455A1
Chemistry; metallurgy

Production of Hydroxylated Fatty Acids in Genetically Modified Plants

#5999 ✅ Patent 8,067,642 granted on 2011-11-29
US20100168456A1
Performing operations; transporting

Chiral phosphorous compounds

#6000 ✅ Patent 8,680,311 granted on 2014-03-25
US20100168457A1
Mechanical engineering

Monolithic electrokinetic pump fabrication