Patent Applications published on Jun 9, 2011 - page 18

#5101 ✅ Patent 8,088,817 granted on 2012-01-03
US20110136794A1
Chemistry; metallurgy

Pyrrole derivative having, as substituents, ureido group, aminocarbonly group and bicyclic group which may have substituent

#5102 ✅ Patent 8,466,168 granted on 2013-06-18
US20110136795A1
Chemistry; metallurgy

Tricyclic alkylaminomethyloxazolidinone derivatives

#5103 ✅ Patent 8,748,469 granted on 2014-06-10
US20110136796A1
Chemistry; metallurgy

IDO inhibitors

#5104 ✅ Patent 8,026,242 granted on 2011-09-27
US20110136797A1
Chemistry; metallurgy

Cyclopropyl amines as modulators of the histamine Hreceptor

#5105 ✅ Patent 8,093,242 granted on 2012-01-10
US20110136798A1
Chemistry; metallurgy

Crystalline forms of a pyridine derivative

#5106 ✅ Patent 8,415,482 granted on 2013-04-09
US20110136799A1
Chemistry; metallurgy

Proline derivatives

#5107 ✅ Patent 8,497,281 granted on 2013-07-30
US20110136800A1
Chemistry; metallurgy

Aryl- and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline

#5108
US20110136801A1
Chemistry; metallurgy

Novel Compounds

#5109 ✅ Patent 8,101,605 granted on 2012-01-24
US20110136802A1
Chemistry; metallurgy

SHIP1 modulators and methods related thereto

#5110
US20110136803A1
Chemistry; metallurgy

Triazolophthalazines

#5111
US20110136804A1
Chemistry; metallurgy

Nicotinic Acetylcholine Receptor Ligands 101

#5112 ✅ Patent 8,399,461 granted on 2013-03-19
US20110136805A1
Chemistry; metallurgy

Bicyclic heterocycles, medicaments containing said compounds, use thereof, and method for production of same

#5113
US20110136806A1
Chemistry; metallurgy

Bicyclic heterocycles, pharmaceutical compositions containing these compounds, the use thereof and processes for the preparation thereof

#5114
US20110136807A1
Chemistry; metallurgy

Bicyclic compositions and methods for modulating a kinase cascade

#5115 ✅ Patent 8,829,203 granted on 2014-09-09
US20110136808A1
Chemistry; metallurgy

3′,6-substituted indirubins and their biological applications

#5116 ✅ Patent 8,207,166 granted on 2012-06-26
US20110136809A1
Chemistry; metallurgy

Substituted pyrazolyl urea derivatives useful in the treatment of cancer

#5117 ✅ Patent 8,410,096 granted on 2013-04-02
US20110136810A1
Human necessities

Antitumor agent, kit and method of treating cancer

#5118 ✅ Patent 8,188,081 granted on 2012-05-29
US20110136811A1
Human necessities

Methods of treating inflammation using prokineticin 1 receptor antagonists

#5119 ✅ Patent 8,389,721 granted on 2013-03-05
US20110136812A1
Chemistry; metallurgy

Solubilized topoisomerase poisons

#5120 ✅ Patent 8,445,491 granted on 2013-05-21
US20110136813A1
Human necessities

Wnt protein signalling inhibitors

#5121 ✅ Patent 8,592,403 granted on 2013-11-26
US20110136814A1
Chemistry; metallurgy

Diazepine and diazocane compounds as MC4 agonists

#5122
US20110136815A1
Human necessities

SOLID ORAL FILM DOSAGE FORMS AND METHODS FOR MAKING SAME

#5123 ✅ Patent 8,394,848 granted on 2013-03-12
US20110136816A1
Chemistry; metallurgy

Compounds that modulate intracellular calcium

#5124 ✅ Patent 8,137,992 granted on 2012-03-20
US20110136817A1
Human necessities

Methods of identifying responders to dopamine agonist therapy and treating metabolic conditions thereof

#5125 ✅ Patent 8,809,334 granted on 2014-08-19
US20110136818A1
Human necessities

Therapeutic compositions containing macitentan

#5126
US20110136819A1
Chemistry; metallurgy

6-THIOXOPYRIDAZINE DERIVATIVES

#5127
US20110136820A1
Human necessities

Heterocyclic Compounds as CCR2 Antagonists

#5128 ✅ Patent 8,383,629 granted on 2013-02-26
US20110136821A1
Chemistry; metallurgy

Inhibitors of 11β-hydroxysteroid dehydrogenase type 1

#5129 ✅ Patent 8,916,567 granted on 2014-12-23
US20110136822A1
Chemistry; metallurgy

Certain crystalline hydrates, pharmaceutical compositions thereof and methods for preparation and use thereof

#5130 ✅ Patent 8,338,599 granted on 2012-12-25
US20110136823A1
Chemistry; metallurgy

Compounds having a potentiating effect on the activity of ethionamide and uses thereof

#5131 ✅ Patent 8,193,191 granted on 2012-06-05
US20110136824A1
Chemistry; metallurgy

Urotensin II receptor antagonists

#5132
US20110136825A1
Human necessities

Treatment of Vasomotor Symptoms

#5133
US20110136826A1
Human necessities

COMBINATIONS FOR THE TREATMENT OF DISEASES INVOLVING CELL PROLIFERATION, MIGRATION OR APOPTOSIS OF MYELOMA CELLS, OR ANGIOGENESIS

#5134 ✅ Patent 9,018,411 granted on 2015-04-28
US20110136827A1
Chemistry; metallurgy

Bis-acylated hydroxylamine derivatives

#5135 ✅ Patent 8,202,874 granted on 2012-06-19
US20110136828A1
Human necessities

Substituted N-oxide pyrazine derivatives

#5136
US20110136829A1
Chemistry; metallurgy

3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS

#5137 ✅ Patent 8,304,416 granted on 2012-11-06
US20110136830A1
Chemistry; metallurgy

Chromenone derivatives

#5138 ✅ Patent 8,378,114 granted on 2013-02-19
US20110136831A1
Chemistry; metallurgy

N-2-(hetero)arylethylcarboxamide derivative, and pest-controlling agent comprising the same

#5139 ✅ Patent 8,530,516 granted on 2013-09-10
US20110136832A1
Human necessities

Promoting cycling of ApoE4 isoform

#5140 ✅ Patent 8,324,249 granted on 2012-12-04
US20110136833A1
Chemistry; metallurgy

Tetrahydropyridinyl and dihydropyrrolyl compounds and the use thereof

#5141
US20110136834A1
Chemistry; metallurgy

INHIBITORS OF E1 ACTIVATING ENZYMES

#5142
US20110136835A1
Human necessities

COMBINATION FORMULATIONS OF TRANILAST AND ALLOPURINOL AND METHODS RELATED THERETO

#5143
US20110136836A1
Human necessities

Methods for Altering MRNA Splicing and Treating Familial Dysautonomia and Other Mechanistically Related Disorders

#5144 ✅ Patent 8,592,434 granted on 2013-11-26
US20110136837A1
Human necessities

Mucoadhesive buccal tablets for the treatment of orofacial herpes

#5145 ✅ Patent 8,383,635 granted on 2013-02-26
US20110136838A1
Chemistry; metallurgy

Chemical compounds

#5146 ✅ Patent 8,273,757 granted on 2012-09-25
US20110136839A1
Human necessities

Combination of two analgesic chemicals

#5147 ✅ Patent 8,450,318 granted on 2013-05-28
US20110136840A1
Human necessities

Method to treat infections using anti-infective agents

#5148 ✅ Patent 8,524,728 granted on 2013-09-03
US20110136841A1
Human necessities

Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase

#5149
US20110136842A1
Chemistry; metallurgy

Substituted Dihydroisoquinolinone and Isoquinolinedione Derivatives as Calcium Channel Blockers

#5150
US20110136843A1
Human necessities

Novel Combination of Compounds to be Used in the Treatment of Airway Diseases, Especially Chronic Obstructive Pulmonary Disease (COPD) and Asthma

#5151
US20110136844A1
Human necessities

METHODS FOR INHIBITING DYRK1A TO TREAT CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS

#5152 ✅ Patent 9,562,014 granted on 2017-02-07
US20110136845A1
Chemistry; metallurgy

(+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof

#5153 ✅ Patent 8,530,494 granted on 2013-09-10
US20110136846A1
Chemistry; metallurgy

Buprenophine analogs

#5154
US20110136847A1
Human necessities

High Concentration Formulations of Opioids and Opioid Derivatives

#5155 ✅ Patent 9,119,848 granted on 2015-09-01
US20110136848A1
Human necessities

Morphinan derivatives for the treatment of drug overdose

#5156 ✅ Patent 9,034,893 granted on 2015-05-19
US20110136849A1
Human necessities

Process for reducing contaminating michael acceptor levels in oxycodone and other compositions

#5157 ✅ Patent 8,431,353 granted on 2013-04-30
US20110136850A1
Chemistry; metallurgy

Methods and compositions for topoisomerase I modulated tumor suppression

#5158
US20110136851A1
Human necessities

Sucralose Formulations To Mask Unpleasant Tastes

#5159
US20110136852A1
Human necessities

Rapamycin Derivative or an Impdh Inhibitor for Treating Polycystic Kidney Disease

#5160
US20110136853A1
Human necessities

LIGAND WITH A BROAD SPECTRUM OF PHARMACOLOGICAL ACTIVITY, A PHARMACEUTICAL COMPOSITION, A MEDICINAL AGENT AND A METHOD OF TREATMENT

#5161
US20110136854A1
Chemistry; metallurgy

NOVEL 9-AZA-BICYCLO[3.3.1]NON-3-YLOXY CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS

#5162
US20110136855A1
Chemistry; metallurgy

GEMIFLOXACIN PROCESS AND POLYMORPHS

#5163 ✅ Patent 8,633,216 granted on 2014-01-21
US20110136856A1
Chemistry; metallurgy

Imidazo[1,5-a]pyridine derivatives, method for preparing same and pharmaceutical compositions containing same

#5164 ✅ Patent 8,198,298 granted on 2012-06-12
US20110136857A1
Chemistry; metallurgy

Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors

#5165
US20110136858A1
Human necessities

Preferred Combination Therapy

#5166 ✅ Patent 8,399,481 granted on 2013-03-19
US20110136859A1
Chemistry; metallurgy

Compounds

#5167 ✅ Patent 8,426,442 granted on 2013-04-23
US20110136860A1
Chemistry; metallurgy

Compounds

#5168 ✅ Patent 8,575,348 granted on 2013-11-05
US20110136861A1
Chemistry; metallurgy

Quinolone inhibitors of lipoprotein-associated phospholipase A2

#5169
US20110136862A1
Chemistry; metallurgy

NOVEL TETRAMETHYL SUBSTITUTED PIPERIDINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS

#5170 ✅ Patent 8,426,598 granted on 2013-04-23
US20110136863A1
Human necessities

N-heterocyclic M1 receptor positive allosteric modulators

#5171 ✅ Patent 8,318,770 granted on 2012-11-27
US20110136864A1
Chemistry; metallurgy

Tetrahydroquinoline indole derivatives and uses thereof

#5172
US20110136865A1
Human necessities

Use of D4 and 5-HT2A antagonists, inverse agonists or partial agonists

#5173 ✅ Patent 8,518,971 granted on 2013-08-27
US20110136866A1
Human necessities

Insecticidal phenyl- or pyridyl-piperdine compounds

#5174
US20110136867A1
Human necessities

Treatment of Synucleinopathies

#5175
US20110136868A1
Human necessities

AGENTS FOR INHIBITING OSTEOCLASTOGENESIS AND/OR OSTEOCLAST ACTIVATION

#5176 ✅ Patent 8,299,103 granted on 2012-10-30
US20110136869A1
Chemistry; metallurgy

Compounds which selectively modulate the CB2 receptor

#5177
US20110136870A1
Human necessities

GACYCLIDINE FORMULATIONS

#5178 ✅ Patent 8,791,146 granted on 2014-07-29
US20110136871A1
Human necessities

2-alkoxy-substituted dicyanopyridines and their use

#5179
US20110136872A1
Human necessities

STABLE AQUEOUS COMPOSITIONS OF PROSTGLANDIN AGONIST PRODRUGS AND METHODS FOR USE THEREOF

#5180 ✅ Patent 8,304,449 granted on 2012-11-06
US20110136873A1
Human necessities

Inhibitors of cyclin dependent kinases and their use

#5181 ✅ Patent 8,927,581 granted on 2015-01-06
US20110136874A1
Chemistry; metallurgy

Fungicidal N-(2-pyridylpropyl) carboxamide derivatives and their oxa, aza and thia analogues

#5182 ✅ Patent 8,642,628 granted on 2014-02-04
US20110136875A1
Chemistry; metallurgy

Pyrrole inhibitors of S-nitrosoglutathione reductase

#5183
US20110136876A1
Human necessities

Altering Pharmacokinetics of Pirfenidone Therapy

#5184
US20110136877A1
Chemistry; metallurgy

2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS

#5185 ✅ Patent 8,633,228 granted on 2014-01-21
US20110136878A1
Human necessities

Amide derivative, pest control agent containing the amide derivative, and pest controlling method

#5186 ✅ Patent 9,597,318 granted on 2017-03-21
US20110136879A1
Chemistry; metallurgy

2-oxothiazole compounds and method of using same for chronic inflammatory disorders

#5187
US20110136880A1
Chemistry; metallurgy

Latrunculin-Based Macrolides and Their Uses

#5188 ✅ Patent 8,470,857 granted on 2013-06-25
US20110136881A1
Chemistry; metallurgy

Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents

#5189 ✅ Patent 8,002,614 granted on 2011-08-23
US20110136882A1
Human necessities

Microbiocidal control in the processing of meat-producing four-legged animals

#5190
US20110136883A1
Human necessities

GRANULATION OF ACTIVE PHARMACEUTICAL INGREDIENTS

#5191 ✅ Patent 8,486,985 granted on 2013-07-16
US20110136884A1
Human necessities

Selective subtype alpha 2 adrenergic agents and methods for use thereof

#5192 ✅ Patent 8,598,221 granted on 2013-12-03
US20110136885A1
Human necessities

Synergistic combination of analgesic compounds

#5193 ✅ Patent 8,008,337 granted on 2011-08-30
US20110136886A1
Chemistry; metallurgy

Azabicyclo[3.2.0] hept-3-yl compounds, a process for their preparation and pharmaceutical compositions containing them

#5194 ✅ Patent 8,404,736 granted on 2013-03-26
US20110136887A1
Human necessities

Heterocyclic amide derivatives as EP4 receptor antagonists

#5195 ✅ Patent 8,258,182 granted on 2012-09-04
US20110136888A1
Chemistry; metallurgy

Substituted 1,3-diphenylpropane derivatives, preparations and uses thereof

#5196 ✅ Patent 8,299,041 granted on 2012-10-30
US20110136889A1
Chemistry; metallurgy

Compositions and their uses directed to acetyl-CoA carboxylases

#5197 ✅ Patent 8,975,237 granted on 2015-03-10
US20110136890A1
Chemistry; metallurgy

Treatment of fibrotic conditions

#5198
US20110136891A1
Chemistry; metallurgy

Nucleic acid molecules and collections thereof, their application and Identification

#5199 ✅ Patent 9,095,126 granted on 2015-08-04
US20110136892A1
Human necessities

Targeting TGF-β as a therapy for Alzheimer's disease

#5200
US20110136893A1
Human necessities

OLIGONUCLEOTIDE-, PROTEIN AND/OR PEPTIDE-POLYMER CONJUGATES

#5201 ✅ Patent 8,431,392 granted on 2013-04-30
US20110136894A1
Chemistry; metallurgy

Shortened Alk1 regulatory fragment

#5202 ✅ Patent 8,563,314 granted on 2013-10-22
US20110136895A1
Human necessities

Methods and compositions for modulating PD1

#5203
US20110136896A1
Chemistry; metallurgy

VARIANT HCMV PP65, IE1, AND IE2 POLYNUCLEOTIDES AND USES THEREOF

#5204
US20110136897A1
Chemistry; metallurgy

TOLL-LIKE RECEPTOR 9 AGONISTS FOR THE TREATMENT OF ANXIETY-RELATED DISORDERS AND INFLAMMATORY DISORDERS

#5205
US20110136898A1
Human necessities

TREATMENT OF RETINAL DEGENERATION

#5206
US20110136899A1
Human necessities

COMBINATION OF DRONEDARONE WITH AT LEAST ONE DIURETIC, AND THERAPEUTIC USE THEREOF

#5207 ✅ Patent 8,399,032 granted on 2013-03-19
US20110136900A1
Human necessities

Bruise amelioration composition and method of use

#5208 ✅ Patent 8,673,971 granted on 2014-03-18
US20110136901A1
Chemistry; metallurgy

Derivatives of 4-nerolidylcatechol, pharmaceutical compositions comprising them and process for producing the same

#5209
US20110136902A1
Chemistry; metallurgy

12-MEMBERED-RING MACROLACTAM DERIVATIVES

#5210 ✅ Patent 8,367,087 granted on 2013-02-05
US20110136903A1
Human necessities

Soil amendment compositions and methods for using the same

#5211 ✅ Patent 8,058,467 granted on 2011-11-15
US20110136904A1
Chemistry; metallurgy

Prostaglandin derivatives

#5212 ✅ Patent 8,598,384 granted on 2013-12-03
US20110136905A1
Chemistry; metallurgy

Crystalline teglicar

#5213 ✅ Patent 8,778,995 granted on 2014-07-15
US20110136906A1
Human necessities

Use of hydroxyoleic acid and related compounds in the manufacture of drugs

#5214 ✅ Patent 7,960,528 granted on 2011-06-14
US20110136907A1
Chemistry; metallurgy

Perhydrolase providing improved peracid stability

#5215 ✅ Patent 7,964,383 granted on 2011-06-21
US20110136908A1
Human necessities

Perhydrolase providing improved peracid stability

#5216
US20110136909A1
Human necessities

METHOD FOR SUPPRESSING EXCESSIVE APPETITE

#5217 ✅ Patent 8,404,266 granted on 2013-03-26
US20110136910A1
Human necessities

Method for stabilization of S-nitrosoglutathione and composition prepared by the same

#5218
US20110136911A1
Human necessities

TREATMENT OF SEPSIS AND INHIBITION OF MIF BY D-T4

#5219
US20110136912A1
Human necessities

OPHTHALMIC EMULSION

#5220
US20110136913A1
Physics

ASSESSING AND TREATING BREAST CANCER PATIENTS

#5221
US20110136914A1
Chemistry; metallurgy

SUBSTITUTED ARYLOXYPROPYLAMINES WITH SEROTONINERGIC AND/OR NOREPINEPHRINERGIC ACTIVITY

#5222 ✅ Patent 9,375,405 granted on 2016-06-28
US20110136915A1
Human necessities

Rapid dissolution formulation of a calcium receptor-active compound

#5223
US20110136916A1
Human necessities

6-SHOGAOL FOR USING IN A METHOD FOR THE TREATMENT OF LEUKEMIA

#5224
US20110136917A1
Physics

TETRAHYDRO-ISOALPHA ACID COMPOSITIONS AND METHODS FOR WEIGHT MANAGEMENT

#5225 ✅ Patent 8,865,774 granted on 2014-10-21
US20110136918A1
Human necessities

Methods of treating infectious diseases

#5226 ✅ Patent 8,962,519 granted on 2015-02-24
US20110136919A1
Chemistry; metallurgy

Precipitated silicic acids for support applications

#5227
US20110136920A1
Human necessities

O/W EMULSION CONTAINING A HYDROPHILIC POLYMER AND A SEMI-CRYSTALLINE POLYMER

#5228
US20110136921A1
Human necessities

SUSTAINED RELEASE COMPOSITION

#5229 ✅ Patent 8,288,160 granted on 2012-10-16
US20110136922A1
Chemistry; metallurgy

Activation induced deaminase (AID)

#5230 ✅ Patent 8,653,148 granted on 2014-02-18
US20110136923A1
Performing operations; transporting

Microwave process and apparatus for breaking emulsions

#5231
US20110136924A1
Performing operations; transporting

CATALYST AND PROCESS FOR PRODUCING LIQUEFIED PETROLEUM GAS

#5232 ✅ Patent 8,673,988 granted on 2014-03-18
US20110136925A1
Chemistry; metallurgy

Graft copolymers for ion exchange chromatography

#5233
US20110136926A1
Performing operations; transporting

Catalysts for Olefin Hydration and Method of Preparation

#5234 ✅ Patent 8,354,463 granted on 2013-01-15
US20110136927A1
Chemistry; metallurgy

Flame retardant thermoplastic elastomers

#5235 ✅ Patent 8,617,786 granted on 2013-12-31
US20110136928A1
Physics

Poly-oxycarbosilane compositions for use in imprint lithography

#5236
US20110136929A1
Physics

TRAPPING GLUCOSE PROBE IN PORES OF POLYMER

#5237
US20110136930A1
Chemistry; metallurgy

METHOD FOR PREPARING VISCOELASTIC POLYURETHANE FOAM

#5238 ✅ Patent 8,703,836 granted on 2014-04-22
US20110136931A1
Chemistry; metallurgy

Modified olefin polymers

#5239 ✅ Patent 8,455,174 granted on 2013-06-04
US20110136932A1
Physics

Polymers, methods of use thereof, and methods of decomposition thereof

#5240 ✅ Patent 8,470,903 granted on 2013-06-25
US20110136933A1
Chemistry; metallurgy

Ultra high molecular weight polyethylene articles and methods of forming ultra high molecular weight polyethylene articles

#5241 ✅ Patent 8,507,178 granted on 2013-08-13
US20110136934A1
Physics

Polychromic substances and their use

#5242
US20110136935A1
Chemistry; metallurgy

BONE AND/OR DENTAL CEMENT COMPOSITION AND USES THEREOF

#5243
US20110136936A1
Chemistry; metallurgy

High PVC Fast-Drying Aqueous Binder Compositions With Small Particle Binders And Traffic Markings Made Therewith

#5244 ✅ Patent 8,729,155 granted on 2014-05-20
US20110136937A1
Chemistry; metallurgy

Intumescent material for fire protection

#5245 ✅ Patent 8,048,941 granted on 2011-11-01
US20110136938A1
Chemistry; metallurgy

Silica/elastomer composite, rubber composition and pneumatic tire

#5246
US20110136939A1
Chemistry; metallurgy

TIRE WITH COMPONENT CONTAINING CELLULOSE

#5247 ✅ Patent 8,129,495 granted on 2012-03-06
US20110136940A1
Chemistry; metallurgy

Coating compositions for containers and methods of coating

#5248 ✅ Patent 8,354,467 granted on 2013-01-15
US20110136941A1
Chemistry; metallurgy

Underfill formulation and method of increasing an adhesion property of same

#5249 ✅ Patent 8,344,059 granted on 2013-01-01
US20110136942A1
Chemistry; metallurgy

Two-component mortar composition suitable for construction purposes, its use and the cured structural objects obtained thereby

#5250 ✅ Patent 8,530,541 granted on 2013-09-10
US20110136943A1
Chemistry; metallurgy

Cement compositions including polymer particles

#5251
US20110136944A1
Chemistry; metallurgy

COPOLYMERS BASED ON UNSATURATED MONO- OR DICARBOXYLIC ACID DERIVATIVES AND OXYALKYLENEGLYCOL-ALKENYL ETHERS, PROCESSES FOR THE PRODUCTION AND USE THEREOF

#5252 ✅ Patent 8,741,989 granted on 2014-06-03
US20110136945A1
Chemistry; metallurgy

Incorporation of a resin dispersion to improve the moisture resistance of gypsum products

#5253
US20110136946A1
Chemistry; metallurgy

SLURRY COMPOSITIONS FOR GROUND IMPROVEMENT USING BLAST-FURNACE SLAG CEMENT AND METHOD OF PRODUCING SOIL CEMENT SLURRY BY USING SAME

#5254 ✅ Patent 8,569,430 granted on 2013-10-29
US20110136947A1
Chemistry; metallurgy

Method of spray drying phenol-formaldehyde resin

#5255 ✅ Patent 8,785,579 granted on 2014-07-22
US20110136948A1
Chemistry; metallurgy

Linear perfluoropolyethers having an improved thermooxidative stability

#5256
US20110136949A1
Chemistry; metallurgy

Molding compositions of a glass fiber-reinforced olefin polymer

#5257 ✅ Patent 9,029,446 granted on 2015-05-12
US20110136950A1
Chemistry; metallurgy

Clarified polypropylene articles with improved optical properties and/or increased temperature of crystallization

#5258 ✅ Patent 8,524,804 granted on 2013-09-03
US20110136951A1
Textiles; paper

Surface-treated fiber, resin composition, and molded article of the composition

#5259 ✅ Patent 8,492,469 granted on 2013-07-23
US20110136952A1
Physics

Positive-type photosensitive resin composition, cured film, protective film, insulating film, and semiconductor device and display device including the cured film

#5260 ✅ Patent 9,115,259 granted on 2015-08-25
US20110136953A1
Chemistry; metallurgy

Filled poly vinyl chloride composition

#5261
US20110136954A1
Human necessities

BIOSOURCED ACROLEIN POLYMER, METHOD FOR OBTAINING SAME, AND USES THEREOF

#5262 ✅ Patent 8,497,219 granted on 2013-07-30
US20110136955A1
Chemistry; metallurgy

Highly temperature-resistant and chemically resistant glass and glass fiber having improved UV light transmission and the use thereof

#5263
US20110136956A1
Chemistry; metallurgy

1,4-CIS-POLYBUTADIENE FUNCTIONALIZED WITH ORGANOSULFUR COMPOUND FOR PREPARATION OF GOLF BALL CORE

#5264
US20110136957A1
Chemistry; metallurgy

Resin Material for Refrigeration Circuit

#5265
US20110136958A1
Chemistry; metallurgy

MIXED ORGANIC AND INORGANIC POLYMERS

#5266 ✅ Patent 9,115,276 granted on 2015-08-25
US20110136959A1
Chemistry; metallurgy

Polyolefin composition with low CLTE

#5267
US20110136960A1
Chemistry; metallurgy

METHOD OF MAKING AN ATOMIZING AGENT

#5268 ✅ Patent 8,846,791 granted on 2014-09-30
US20110136961A1
Performing operations; transporting

Tire rubber composition and pneumatic tire

#5269 ✅ Patent 8,455,582 granted on 2013-06-04
US20110136962A1
Chemistry; metallurgy

Tire rubber composition and pneumatic tire

#5270
US20110136963A1
Chemistry; metallurgy

METHOD FOR SNYTHESIZING AMPHIPHILIC GRADIENT COPOLYMERS SOLUBLE IN AN ALKALINE MEDIUM

#5271
US20110136964A1
Chemistry; metallurgy

COLORING PROCESS FOR POLY (METH) ACRYLATES WITH WATER-BASED LIQUID DYES AND WATER-BASED LIQUID DYES

#5272 ✅ Patent 8,822,591 granted on 2014-09-02
US20110136965A1
Chemistry; metallurgy

Pigment dispersions

#5273 ✅ Patent 8,889,784 granted on 2014-11-18
US20110136966A1
Chemistry; metallurgy

Crosslinkable polymer dispersion

#5274 ✅ Patent 8,119,752 granted on 2012-02-21
US20110136967A1
Chemistry; metallurgy

Method for producing ethylene copolymers

#5275 ✅ Patent 8,669,321 granted on 2014-03-11
US20110136968A1
Chemistry; metallurgy

Tire rubber composition and pneumatic tire

#5276 ✅ Patent 9,074,073 granted on 2015-07-07
US20110136969A1
Chemistry; metallurgy

Rubber composition containing silica reinforcement and functionalized crosslinks and products with component thereof

#5277 ✅ Patent 8,143,344 granted on 2012-03-27
US20110136970A1
Chemistry; metallurgy

Method of making a silica/elastomer composite

#5278 ✅ Patent 8,784,616 granted on 2014-07-22
US20110136971A1
Chemistry; metallurgy

Pyrolysis systems, methods, and resultants derived therefrom

#5279
US20110136972A1
Chemistry; metallurgy

THERMAL CURABLE POWDER COATING COMPOSITION

#5280
US20110136973A1
Electricity

POLYBENZOTHIOPHENE POLYMERS AND PROCESS FOR THEIR PREPARATION

#5281 ✅ Patent 8,227,565 granted on 2012-07-24
US20110136974A1
Human necessities

Polyurethane compositions for golf balls

#5282
US20110136975A1
Chemistry; metallurgy

MONOMER MIXTURE, POLYMER, COATING MEANS AND METHOD FOR PRODUCING A COATING

#5283
US20110136976A1
Chemistry; metallurgy

AQUEOUS POLYURETHANE RESIN DISPERSION AND PROCESS FOR PREPARING THE SAME

#5284 ✅ Patent 8,697,889 granted on 2014-04-15
US20110136977A1
Chemistry; metallurgy

Metal compound, polymerizable composition containing the same, resin, method for producing the resin, and use of the resin

#5285 ✅ Patent 8,445,604 granted on 2013-05-21
US20110136978A1
Human necessities

Thermoformed article made from polybutylene succinate (PBS) and modified polybutylene succinate (MPBS)

#5286 ✅ Patent 8,426,519 granted on 2013-04-23
US20110136979A1
Chemistry; metallurgy

Silicone-thermoplastic polymer reactive blends and copolymer products

#5287 ✅ Patent 8,466,214 granted on 2013-06-18
US20110136980A1
Chemistry; metallurgy

Core-shell impact modifiers for transparent polymer matrices

#5288
US20110136981A1
Chemistry; metallurgy

BUTENE-1 COPOLYMERS AND PROCESS FOR THEIR PREPARATION

#5289 ✅ Patent 8,410,217 granted on 2013-04-02
US20110136982A1
Chemistry; metallurgy

Thermoplastic polyolefin blends

#5290 ✅ Patent 9,574,064 granted on 2017-02-21
US20110136983A1
Chemistry; metallurgy

Processes and compositions for injection blow molding

#5291 ✅ Patent 8,372,921 granted on 2013-02-12
US20110136984A1
Chemistry; metallurgy

Process for brominating unsaturated organic compounds using a quaternary phosphonium tribromide as the brominating agent

#5292
US20110136985A1
Performing operations; transporting

MOLDED ARTICLE HAVING A MOLD IMPARTED RELEASE LAYER COATING

#5293 ✅ Patent 8,410,233 granted on 2013-04-02
US20110136986A1
Chemistry; metallurgy

Method for producing superabsorbers with a low residual monomer content

#5294 ✅ Patent 8,354,473 granted on 2013-01-15
US20110136987A1
Chemistry; metallurgy

Halogenation processes

#5295
US20110136988A1
Chemistry; metallurgy

CONDENSATION POLYMERS WITH MODIFIED PROPERTIES

#5296 ✅ Patent 8,829,120 granted on 2014-09-09
US20110136989A1
Chemistry; metallurgy

Polyetheramide compositions

#5297
US20110136990A1
Human necessities

POLYMER DERIVATIVE OF DOCETAXEL, METHOD OF PREPARING THE SAME AND USES THEREOF

#5298 ✅ Patent 8,519,062 granted on 2013-08-27
US20110136991A1
Chemistry; metallurgy

Elastomeric materials having a high hardblock content and process for preparing them

#5299
US20110136992A1
Chemistry; metallurgy

COMPOSITION FOR INSULATING LAYER

#5300
US20110136993A1
Chemistry; metallurgy

PHOSPHORUS-CONTAINING COMPOUNDS AND POLYMERIC COMPOSITIONS COMPRISING SAME

#5301
US20110136994A1
Chemistry; metallurgy

OLEFIN POLYMERIZATION CATALYST AND PRODUCTION PROCESS OF OLEFIN POLYMER

#5302 ✅ Patent 8,507,627 granted on 2013-08-13
US20110136995A1
Performing operations; transporting

Aromatic vinyl compound-conjugated diene compound copolymer and method of producing the same as well as rubber composition and tire

#5303 ✅ Patent 8,697,599 granted on 2014-04-15
US20110136996A1
Chemistry; metallurgy

Methods of preparing a polymerization catalyst

#5304 ✅ Patent 7,951,883 granted on 2011-05-31
US20110136997A1
Chemistry; metallurgy

Preparation of multimodal, high density, ethylene homopolymer barrier resins and films

#5305 ✅ Patent 10,207,238 granted on 2019-02-19
US20110136998A1
Performing operations; transporting

Catalyst composition with mixed selectivity control agent and method

#5306 ✅ Patent 8,138,274 granted on 2012-03-20
US20110136999A1
Chemistry; metallurgy

Process for preparation of fluorosilicon polymer

#5307 ✅ Patent 8,637,620 granted on 2014-01-28
US20110137000A1
Chemistry; metallurgy

Method for preparing polymer materials doped with metal elements and resulting materials

#5308
US20110137001A1
Chemistry; metallurgy

COPOLYMER FOR IMPROVED DRYING

#5309 ✅ Patent 8,617,858 granted on 2013-12-31
US20110137002A1
Chemistry; metallurgy

Method for the enzyme-catalysed hydrolysis of polyacrylic acid esters, and esterases used therefor

#5310 ✅ Patent 8,314,191 granted on 2012-11-20
US20110137003A1
Chemistry; metallurgy

Classified catalyst composition, apparatus, and method

#5311 ✅ Patent 8,889,653 granted on 2014-11-18
US20110137004A1
Human necessities

Grafting polymerization of guar and other polysaccharides by electron beams

#5312 ✅ Patent 8,080,626 granted on 2011-12-20
US20110137005A1
Chemistry; metallurgy

Chain extenders

#5313 ✅ Patent 9,790,318 granted on 2017-10-17
US20110137006A1
Chemistry; metallurgy

Methods for polymerizing films in-situ

#5314 ✅ Patent 8,093,346 granted on 2012-01-10
US20110137007A1
Chemistry; metallurgy

Method for producing an aminohydroxybenzoic acid-type compound

#5315 ✅ Patent 8,106,147 granted on 2012-01-31
US20110137008A1
Chemistry; metallurgy

High strength polyimide membrane and method for forming the same

#5316 ✅ Patent 8,426,550 granted on 2013-04-23
US20110137009A1
Chemistry; metallurgy

Polyamic acid, polyimide, manufacturing method thereof, and polyimide film

#5317 ✅ Patent 8,541,569 granted on 2013-09-24
US20110137010A1
Chemistry; metallurgy

Phosphoramidites for synthetic RNA in the reverse direction, efficient RNA synthesis and convenient introduction of 3'-end ligands, chromophores and modifications of synthetic RNA

#5318
US20110137011A1
Chemistry; metallurgy

HYPERGLYCOSYLATED HUMAN COAGULATION FACTOR IX

#5319
US20110137012A1
Chemistry; metallurgy

CELL CULTURE METHOD USING AMINO ACID-ENRICHED MEDIUM

#5320 ✅ Patent 8,173,775 granted on 2012-05-08
US20110137013A1
Chemistry; metallurgy

Collagen-like protein CLAC, a precursor thereof, and genes encoding the same

#5321
US20110137014A1
Chemistry; metallurgy

SUPER HUMANIZED ANTIBODIES

#5322 ✅ Patent 8,183,349 granted on 2012-05-22
US20110137015A1
Chemistry; metallurgy

Markers of XMRV infection and uses thereof

#5323 ✅ Patent 8,535,675 granted on 2013-09-17
US20110137016A1
Chemistry; metallurgy

Compositions and methods for the diagnosis and treatment of tumor

#5324
US20110137017A1
Human necessities

CYSTEINE ENGINEERED ANTIBODIES AND CONJUGATES

#5325
US20110137018A1
Physics

MAGNETIC SEPARATION SYSTEM WITH PRE AND POST PROCESSING MODULES

#5326 ✅ Patent 8,957,191 granted on 2015-02-17
US20110137019A1
Chemistry; metallurgy

Nucleic acid comprising zwitterionic nucleotides

#5327 ✅ Patent 8,158,349 granted on 2012-04-17
US20110137020A1
Performing operations; transporting

Method and device for purifying nucleic acids

#5328 ✅ Patent 8,552,175 granted on 2013-10-08
US20110137021A1
Chemistry; metallurgy

Sulfur transfer reagents for oligonucleotide synthesis

#5329
US20110137022A1
Chemistry; metallurgy

METHOD FOR THE ANALYSIS OF OLIGONUCLEOTIDES

#5330 ✅ Patent 8,629,265 granted on 2014-01-14
US20110137023A1
Chemistry; metallurgy

Method for producing phosphate-bridged nucleoside conjugates

#5331 ✅ Patent 8,481,753 granted on 2013-07-09
US20110137024A1
Chemistry; metallurgy

Method for producing isoindole

#5332 ✅ Patent 8,946,454 granted on 2015-02-03
US20110137025A1
Chemistry; metallurgy

Chemical framework compositions and methods of use

#5333 ✅ Patent 8,865,697 granted on 2014-10-21
US20110137026A1
Chemistry; metallurgy

Crystalline (6R,7R)-7-{2-(5-amino-[1,2,4] thiadiazol-3-yl)-2-[(Z)-trityloxyimino]-acetylamino}-3-[(R)-1′-tert-butoxycarbonyl-2-oxo-[1,3′]bipyrrolidinyl-(3E)-ylidenemethyl]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester; its manufacture and use

#5334
US20110137027A1
Chemistry; metallurgy

METHOD FOR PREPARING LACTAMES, COMPRISING A PHOTONITROSATION STEP, FOLLOWED BY A BECKMANN TRANSPOSITION STEP

#5335 ✅ Patent 8,569,494 granted on 2013-10-29
US20110137028A1
Human necessities

Methods of synthesis and purification of heteroaryl compounds

#5336 ✅ Patent 8,318,982 granted on 2012-11-27
US20110137029A1
Performing operations; transporting

Catalyst and process for preparing an amine

#5337 ✅ Patent 8,487,135 granted on 2013-07-16
US20110137030A1
Chemistry; metallurgy

Catalyst and process for preparing an amine

#5338 ✅ Patent 8,106,194 granted on 2012-01-31
US20110137031A1
Chemistry; metallurgy

Pyrrolopyrimidine and pyrrolotriazine derivatives

#5339 ✅ Patent 8,536,176 granted on 2013-09-17
US20110137032A1
Chemistry; metallurgy

GPR119 agonist

#5340
US20110137033A1
Chemistry; metallurgy

PROCESS FOR PREPARING (4,6-DIMETHYLPYRIMIDIN-2-YL)PHENYLAMINE (PYRIMETHANIL)

#5341 ✅ Patent 8,536,151 granted on 2013-09-17
US20110137034A1
Chemistry; metallurgy

Process for preparing lamivudine polymorph form

#5342
US20110137035A1
Chemistry; metallurgy

PREPARATION OF MICROBIOLOGICALLY PRODUCED ERGOT ALKALOIDS

#5343 ✅ Patent 8,680,276 granted on 2014-03-25
US20110137036A1
Chemistry; metallurgy

Synthesis of (4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridine

#5344 ✅ Patent 8,168,798 granted on 2012-05-01
US20110137037A1
Chemistry; metallurgy

Caspase inhibitor prodrugs

#5345
US20110137038A1
Chemistry; metallurgy

SYNTHESIS OF SELECTED STEREOISOMERS OF CERTAIN SUBSTITUTED ALCOHOLS

#5346
US20110137039A1
Chemistry; metallurgy

PROCESS FOR THE PREPARATION OF MONTELUKAST AND ITS SALTS

#5347
US20110137040A1
Chemistry; metallurgy

SYNTHESIS OF 3,4-DIARYL-4,5-DIHYDRO-(H)-PYRAZOLE-1-CARBOXAMIDINE DERIVATIVES

#5348
US20110137041A1
Chemistry; metallurgy

PROCESS FOR PREPARING ATOVAQUONE AND ASSOCIATE INTERMEDIATES

#5349
US20110137042A1
Chemistry; metallurgy

Process for Synthesis of Intermediates Useful for Making Substituted Indazole and Azaindazole Compounds

#5350
US20110137043A1
Chemistry; metallurgy

Process for the preparation of bidentate schiff base ruthenium catalysts containing a salicylaldimine-type ligand

#5351 ✅ Patent 8,143,416 granted on 2012-03-27
US20110137044A1
Chemistry; metallurgy

Alternative synthesis of renin inhibitors and intermediates thereof

#5352 ✅ Patent 8,093,402 granted on 2012-01-10
US20110137045A1
Chemistry; metallurgy

Benzimidazole derivatives

#5353
US20110137046A1
Chemistry; metallurgy

PREPARATION METHOD OF (4S,5R)-SEMIESTER

#5354
US20110137047A1
Chemistry; metallurgy

Process for enantiomerically pure 8-Aryloctanoic acids as Aliskiren

#5355 ✅ Patent 8,350,056 granted on 2013-01-08
US20110137048A1
Chemistry; metallurgy

Functionalized N-substituted pyrrolidonium ionic liquids

#5356
US20110137049A1
Chemistry; metallurgy

CHIRAL IRIDIUM AQUA COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE HYDROXY COMPOUND USING THE SAME

#5357
US20110137050A1
Chemistry; metallurgy

Process for the Preparation of 4,7-Dimethoxy-5-Methyl-1,3-Benzodioxole and Derivatives Thereof

#5358 ✅ Patent 8,530,695 granted on 2013-09-10
US20110137051A1
Chemistry; metallurgy

Process for recovery of formic acid

#5359 ✅ Patent 8,115,020 granted on 2012-02-14
US20110137052A1
Chemistry; metallurgy

Processes for the preparation and purification of hydroxymethylfuraldehyde and derivatives

#5360 ✅ Patent 8,569,525 granted on 2013-10-29
US20110137053A1
Chemistry; metallurgy

Process for producing ethylene oxide

#5361 ✅ Patent 8,729,282 granted on 2014-05-20
US20110137054A1
Chemistry; metallurgy

Process for the manufacture of a 1,2-epoxide

#5362 ✅ Patent 8,802,873 granted on 2014-08-12
US20110137055A1
Chemistry; metallurgy

Process for the manufacture of epichlorohydrin

#5363
US20110137056A1
Chemistry; metallurgy

Chemical Process For Preparation Of Intermediates

#5364 ✅ Patent 8,586,770 granted on 2013-11-19
US20110137057A1
Human necessities

Unsaturated steroid compounds

#5365
US20110137058A1
Chemistry; metallurgy

PREPARATION OF PARICALCITOL

#5366 ✅ Patent 8,816,113 granted on 2014-08-26
US20110137059A1
Chemistry; metallurgy

Process for the carbonylation of ethylenically unsaturated compounds, novel carbonylation ligands and catalyst systems incorporating such ligands

#5367
US20110137060A1
Chemistry; metallurgy

PREPARATION OF ANSA METALLOCENE COMPOUNDS

#5368
US20110137061A1
Chemistry; metallurgy

NANOINK FOR FORMING ABSORBER LAYER OF THIN FILM SOLAR CELL AND METHOD OF PRODUCING THE SAME

#5369 ✅ Patent 8,241,922 granted on 2012-08-14
US20110137062A1
Physics

Surface enhanced Raman spectroscopy using shaped gold nanoparticles

#5370
US20110137063A1
Chemistry; metallurgy

COMPOUNDS AND PROCESSES FOR PRODUCTION OF RADIOPHARMACEUTICALS

#5371
US20110137064A1
Physics

METHACRYLATE-BOUND PHOTOISOMERIZABLE CHROMOPHORE, METHODS FOR ITS SYNTHESIS

#5372
US20110137065A1
Chemistry; metallurgy

PROCESSES FOR SYNTHESIZING 1-(2-ETHYLBUTYL)CYCLOHEXANE CARBONITRILE

#5373
US20110137066A1
Chemistry; metallurgy

PROCESS OF INHIBITING POLYMERIZATION OF ISOCYANATE GROUP-CONTAINING, ETHYLENICALLY UNSATURATED CARBOXYLATE COMPOUNDS, AND PROCESS FOR PRODUCING THE COMPOUNDS

#5374 ✅ Patent 8,729,291 granted on 2014-05-20
US20110137067A1
Chemistry; metallurgy

Method for producing urethanes composed of di-functional aromatic amines and dialkyl carbonates

#5375 ✅ Patent 8,853,440 granted on 2014-10-07
US20110137068A1
Chemistry; metallurgy

Method for producing amide derivative

#5376 ✅ Patent 8,541,615 granted on 2013-09-24
US20110137069A1
Chemistry; metallurgy

Method for producing biphenyltetracarboxylic acid tetraester

#5377 ✅ Patent 8,476,470 granted on 2013-07-02
US20110137070A1
Chemistry; metallurgy

Process for production of bicyclo[2.2.2]octylamine derivative

#5378 ✅ Patent 8,049,043 granted on 2011-11-01
US20110137071A1
Chemistry; metallurgy

Processes related to the hydroformylation of butenes

#5379 ✅ Patent 8,586,791 granted on 2013-11-19
US20110137072A1
Chemistry; metallurgy

Method for producing (meth)acrylic anhydride, method for storing (meth)acrylic anhydride, and method for producing (meth)acrylate

#5380 ✅ Patent 8,466,310 granted on 2013-06-18
US20110137073A1
Chemistry; metallurgy

Process for producing α-substituted norbornanyl acrylates

#5381 ✅ Patent 8,440,855 granted on 2013-05-14
US20110137074A1
Chemistry; metallurgy

Process for the production of acetic acid ethylene and vinyl acetate monomer

#5382
US20110137075A1
Chemistry; metallurgy

Vinyl acetate production process

#5383 ✅ Patent 8,334,402 granted on 2012-12-18
US20110137076A1
Chemistry; metallurgy

Biological buffers with wide buffering ranges

#5384 ✅ Patent 8,492,584 granted on 2013-07-23
US20110137077A1
Chemistry; metallurgy

Process and apparatus for oxidizing organic compounds

#5385
US20110137078A1
Chemistry; metallurgy

Catalyst And Method For Producing Unsaturated Aldehyde And Unsaturated Carboxylic Acid

#5386 ✅ Patent 8,222,449 granted on 2012-07-17
US20110137079A1
Chemistry; metallurgy

Metal oxide-chelating ligands

#5387
US20110137080A1
Chemistry; metallurgy

PROCESS AND APPARATUS FOR RECOVERY OF ACETIC ACID FROM A FEED STREAM CONTAINING THE CORRESPONDING ESTER

#5388
US20110137081A1
Chemistry; metallurgy

Continuous Method For Producing Amides Of Low Aliphatic Carboxylic Acids

#5389
US20110137082A1
Chemistry; metallurgy

CHARGE-ENHANCING ADDITIVES FOR ELECTRETS

#5390
US20110137083A1
Performing operations; transporting

CONTINUOUS METHOD AND REACTOR FOR HYDROGENATING ORGANIC COMPOUNDS

#5391
US20110137084A1
Chemistry; metallurgy

METHOD FOR PRODUCING PURE OR ENRICHED Q10 COENZYME

#5392 ✅ Patent 8,383,864 granted on 2013-02-26
US20110137085A1
Chemistry; metallurgy

Method for the conversion of cellulose and related carbohydrate materials to low-molecular-weight compounds

#5393 ✅ Patent 8,558,030 granted on 2013-10-15
US20110137086A1
Chemistry; metallurgy

Process for telomerization of butadiene

#5394 ✅ Patent 8,143,456 granted on 2012-03-27
US20110137087A1
Chemistry; metallurgy

Method of reducing methanol in recycle streams in bisphenol-A production process

#5395
US20110137088A1
Chemistry; metallurgy

Methods and Apparatuses for Producing Renewable Materials From Inhibiting Compounds

#5396 ✅ Patent 8,642,667 granted on 2014-02-04
US20110137089A1
Performing operations; transporting

Process for increasing hydrogen content of synthesis gas

#5397 ✅ Patent 8,198,491 granted on 2012-06-12
US20110137090A1
Chemistry; metallurgy

Process for preparing 2,3,3,3-tetrafluoropropene and 1,3,3,3-tetrafluoropropene

#5398
US20110137091A1
Chemistry; metallurgy

Manufacture of Oligomers from Nonene

#5399 ✅ Patent 8,461,404 granted on 2013-06-11
US20110137092A1
Performing operations; transporting

Aromatization catalyst comprising prolongated silica and methods of making and using same

#5400 ✅ Patent 8,673,804 granted on 2014-03-18
US20110137093A1
Chemistry; metallurgy

Enhancing catalytic activity of nanoporous materials