Surgical instrument having force feedback capabilities

A surgical instrument. The surgical instrument has a force delivery system which communicates a changing force to a user of the surgical instrument when a limit of a surgical function is reached. A sensor senses position of a moving element to communicate a signal to the force delivery system. In various embodiments, the system generates a vibratory force to signal the user.

Method for determining driving characteristics of a vehicle

To provide an enhanced method to determine from a driving characteristics of the vehicle a long term mechanical stress of a vehicle, it is proposed that during operation of the vehicle an acceleration of the vehicle is detected by an acceleration sensor in the vehicle and evaluated by a vehicle analyzing system in the vehicle, wherein a driving parameter occurring during an acceleration event in which the vehicle acceleration is above a predetermined threshold is used to determine a driving characteristics value of the vehicle.

Simultaneous spatio-temporal measurement of gene expression and cellular activity

Provided herein are methods for simultaneous spatio-temporal measurement of gene expression and cellular activity.

Methods for spatial analysis using targeted RNA depletion

Provided herein are methods for spatial analysis using targeted RNA depletion.

Methods of Detecting Analytes

Localized detection of RNA in a tissue sample that includes cells is accomplished on an array. The array include a number of features on a substrate. Each feature includes a different capture probe immobilized such that the capture probe has a free 3′ end. Each feature occupies a distinct position on the array and has an area of less than about 1 mm2. Each capture probe is a nucleic acid molecule, which includes a positional domain including a nucleotide sequence unique to a particular feature, and a capture domain including a nucleotide sequence complementary to the RNA to be detected. The capture domain can be at a position 3′ of the positional domain.

INTEGRATION OPTIMIZATION USING MACHINE LEARNING ALGORITHMS

A method comprises receiving configuration data comprising a plurality of parameters of at least one computing environment. One or more of the parameters correspond to integration of one or more elements of the least one computing environment with one or more other elements at least one of within and external to the least one computing environment. In the method, the parameters are analyzed to detect one or more anomalies in the configuration data, and the configuration data and the one or more detected anomalies are inputted to one or more machine learning models. The method also comprises determining, using the one or more machine learning models, one or more modifications to at least one of the plurality of parameters based on the inputted configuration data and one or more detected anomalies, and transmitting the determination comprising the one or more modifications to a user over a communications network.

Hydraulic fracturing system for driving a plunger pump with a turbine engine

The present invention discloses a hydraulic fracturing system for driving a plunger pump with a turbine engine, including a fracturing equipment comprising a turbine engine fueled by natural gas or diesel as a power source, an exhaust system, and a plunger pump; a high-low pressure manifold; a blending equipment adapted to blend a fracturing base fluid; and a sand-mixing equipment adapted to provide the fracturing base fluid and a fracturing proppant to the high-low pressure manifold. A first end of the high-low pressure manifold is connected to the fracturing equipment through a connection pipeline. A second end of the high-low pressure manifold is connected to a wellhead. An exhaust end of the turbine engine is connected to the exhaust system whereas an output driving end of the turbine engine is connected to the plunger pump via a connection device. The connection device comprises at least a reduction gearbox. An input speed of the reduction gearbox matches an output driving speed of the turbine engine, and an input torque of the reduction gearbox matches an output driving torque of the turbine engine.

Devices, methods, and graphical user interfaces for interacting with three-dimensional environments

A computer system displays a first view of a three-dimensional environment. While displaying the first view, the computer system detects a first movement of a first hand that meets first criteria, and in response, displays a first virtual object that includes a first plurality of selectable controls at a first position in the first view, wherein the first position corresponds to a location of the first hand after the first movement in a physical environment. While displaying the first virtual object at the first position, the computer system detects a second movement of the first hand, and in response, displays movement of a representation of the first hand in the first view in accordance with the second movement of the first hand relative to a position of the first virtual object in the first view.

Fracturing apparatus and fracturing system

A fracturing apparatus and a fracturing system are provided. The fracturing apparatus includes: a plunger pump configured to pressurize a fracturing fluid to form a high-pressure fracturing fluid; a turbine engine coupled to the plunger pump and configured to provide a driving force to the plunger pump; an auxiliary unit including a driving electric motor, the auxiliary unit being configured to provide the fracturing apparatus with at least one selected from the group consisting of start-up assist function, lubrication function, cooling function, and air supply function; and a power supply electrically coupled to the driving electric motor of the auxiliary unit to provide driving power.

Fracturing device

A fracturing device, including a power unit, wherein the power unit comprises a muffling compartment, a turbine engine, an air intake unit, and a starter; the air intake unit is communicated with the turbine engine through an intake pipe, and configured to provide a combustion-supporting gas to the turbine engine; the air intake unit is located at the top of the muffling compartment, the muffling compartment comprises an accommodation space, the turbine engine and the starter are located in the accommodation space, and the starter is configured to start the turbine engine, the starter comprises a first electric motor.