CONTINUOUS NONINVASIVE BLOOD PRESSURE MEASUREMENT

A blood pressure monitoring system may include an acoustic exciter configured to receive an electrical input signal and to produce an acoustic signal and an acoustic detector spaced apart from the acoustic exciter. The acoustic detector may be configured to detect the acoustic signal and to produce an electrical output signal. The acoustic exciter may be provided on a first substrate portion and the acoustic detector may be provided on a second substrate portion that is acoustically decoupled from the first substrate portion. The blood pressure monitoring system may also include a processor configured to determine a blood pressure measurement from the electrical output signal.

PULSE OXIMETRY SYSTEM

A pulse oximetry system for measuring at least one physiological parameter includes a wearable device configured to be secured to a subject's foot, a sensor hub that is removably securable to the wearable device, and a sensor strap connected to the sensor hub and configured to be wrapped around the subject's foot and secured to the wearable device. In some implementations, the wearable device is configured such that the cavity is positioned adjacent a bottom portion of the subject's foot. The system further includes one or more emitters arranged within the sensor hub and configured to face toward said bottom portion of the subject's foot and one or more detectors arranged within the sensor strap and configured to be positioned adjacent a top portion of the subject's foot.

ENTERPRISE CYBERSECURITY AI PLATFORM

A method includes obtaining data associated with operation of a monitored system. The method also includes using one or more first machine learning models to identify anomalies in the monitored system based on the obtained data, where each anomaly identifies an anomalous behavior. The method further includes using one or more second machine learning models to classify each of at least some of the identified anomalies into one of multiple classifications. Different ones of the classifications are associated with different types of cyberthreats to the monitored system, and the identified anomalies are classified based on risk scores determined using the one or more second machine learning models. In addition, the method includes identifying, for each of at least some of the anomalies, one or more actions to be performed in order to counteract the cyberthreat associated with the anomaly.

Low latency and low defect media file transcoding using optimized storage, retrieval, partitioning, and delivery techniques

Systems, methods and computer program products for high-performance, low latency start-up of large shared media files. A method for low latency startup with low defect playback commences upon identifying a first media file having a first format to be converted to a second media file having a second format. A scheduler divides the first media file into multiple partitions separated by partition boundaries. The method continues by converting the partitions into respective converted partitions that comport with the second format. Determinations as to the position of the partition boundaries is made based on measurable conditions present at a particular moment in time. Different formats receive different treatment based on the combination of characteristics of the first format, characteristics of the second format, as well as on characteristics of measurable conditions present at the moment in time just before conversion of a segment.

DE-CROSSLINKING COMPOUNDS AND METHODS OF USE FOR SPATIAL ANALYSIS

Provided herein are methods for de-crosslinking fixed biological samples (e.g., fixed biological samples including aminal crosslinks). The compositions and methods disclosed can de-crosslink oligonucleotides (e.g., DNA or RNA) or proteins from fixed biological samples (e.g., fixed biological samples with aminal crosslinks), wherein the de-crosslinked biological sample is compatible with and can be used in spatial gene expression analysis.

Nucleic acid library methods

Provided herein are methods, compositions, and kits for removing a portion of a sequence in a member of a nucleic acid library.

METHOD FOR TRANSPOSASE MEDIATED SPATIAL TAGGING AND ANALYZING GENOMIC DNA IN A BIOLOGICAL SAMPLE

The present disclosure relates to materials and methods for spatially analyzing nucleic acids fragmented with a transposase enzyme, optionally complexed to an antibody-binding moiety (e.g., an antibody-binding protein) bound to an antibody for at least one chromatin protein, in a biological sample.

Apparatus and methods for receiving discharged urine

A system suitable for collecting and transporting urine away from the body of a person or animal may include an assembly having a fluid impermeable casing having a fluid reservoir at a first end, a fluid outlet at a second end, and a longitudinally extending fluid impermeable layer coupled to the fluid reservoir and the fluid outlet and defining a longitudinally elongated opening between the reservoir and the outlet. The assembly can further include a fluid permeable support disposed within the casing with a portion extending across the elongated opening, and a fluid permeable membrane disposed on the support and covering at least the portion of the support that extends across the elongated opening, so that the membrane is supported on the support and disposed across the elongated opening. The assembly can further include a tube having a first end disposed in the reservoir and a second, fluid discharge end.

EMPTY CLIP CARTRIDGE LOCKOUT

A surgical device for clipping tissue can include a replaceable cartridge comprising a stack of clips contained therein and a firing drive configured to reciprocatingly eject, or deploy, the clips from the cartridge. After the clips have been deployed from the cartridge, a blocking member can be positioned to impede or block the firing drive. In at least one embodiment, the cartridge can include a biasing member configured to bias the blocking member into a firing chamber defined in the cartridge and/or surgical device. The surgical device can also include a crimping drive configured to deform a clip after it has been ejected from the cartridge. The blocking member can also be configured to impede or block the crimping drive after all of the clips from the cartridge have been used.

Photovoltaic module systems and methods

Some embodiments of the present disclosure relate to methods that may include attaching a first photovoltaic module and a second photovoltaic module to a back-sheet, wherein the first photovoltaic module includes a first end and a second end, and wherein the second photovoltaic module includes a first end and a second end; forming a seam on the back-sheet between the first and second photovoltaic modules; forming an electrical connection between the first and second photovoltaic modules by electrically connecting the first end of the first photovoltaic module to the second end of the second photovoltaic module; and separating the first and second photovoltaic modules along the seam while maintaining the electrical connection between the first and second photovoltaic modules. Some embodiments of the present disclosure relate to roofing systems that may include photovoltaic modules.