Explore the 6,879 U.S. Patent Applications published on the 32nd week of 2025, including 1,142 applications that subsequently received a Patent Grant.
CRISPR ENZYMES AND SYSTEMS
New systems and methods have been created to target specific pieces of DNA. These systems use a special protein from CRISPR technology, along with a guide RNA that helps direct the protein to the right DNA. The invention includes ways to make these systems and how to use them effectively. It also covers the products that can result from using these methods. Overall, this technology aims to improve our ability to edit genes accurately.
Published: 2025-08-07 Assignee: President and Fellows of Harvard College, MASSACHUSETTS INSTITUTE OF TECHNOLOGY, THE BROAD INSTITUTE, INC..
CRISPR ENZYMES AND SYSTEMS
New systems and methods have been developed to target specific pieces of DNA. These systems use a special protein called a CRISPR effector, which is designed to find and attach to the DNA. They also include a guide RNA that helps direct the protein to the right spot in the DNA. The invention explains how to create and use these systems effectively. Overall, it offers new ways to work with and manipulate genetic material.
Published: 2025-08-07 Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, THE BROAD INSTITUTE, INC..
CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION
CRISPR-Cas systems allow scientists to change specific DNA sequences in living organisms. These systems include special tools called vectors that help deliver the CRISPR components into cells. Researchers can design these vectors to target particular genes for editing. The technology can be used to create precise changes in the DNA of eukaryotic cells, which are cells with a nucleus. Additionally, it enables the selection of specific cells that have been modified in desired ways.
Published: 2025-08-07 Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION.
PERSONALIZED REAL-TIME ADVERTISEMENT CONTENT GENERATION
A system predicts which product a user is most likely to prefer from a selection of items. It uses a trained neural network along with data about the user and the current availability of products. In real time, it creates a personalized script that includes a special offer for that preferred product. Then, it generates customized content, which can include audio or video, based on the script and the user's preferences. Finally, this tailored content is displayed on the user's device.
Published: 2025-08-07 Assignee: LG ELECTRONICS INC..
ARTIFICIAL INTELLIGENCE DEVICE FOR A HYBRID NEURAL RENDERING MODEL FOR 3D ANIMATION AND METHOD THEREOF
A device uses a two-dimensional (2D) image to create a three-dimensional (3D) animation. It combines two sets of triangles: one set forms a basic mesh, while the other includes special features and transparency maps. The device adjusts these triangles according to specific animation settings and rigging information. It then applies different rendering techniques to show the animated 3D object. Finally, the result is displayed, bringing the 3D animation to life based on the original 2D image.
Published: 2025-08-07
ULTRA-SENSITIVE LIQUID BIOPSY THROUGH DEEP LEARNING EMPOWERED WHOLE GENOME SEQUENCING OF PLASMA
Researchers have developed a method to detect cancer markers in blood samples using advanced computer technology. They analyze DNA fragments from a patient's plasma and compare them to known reference sequences. By using two trained computer models, they assess the likelihood of these fragments being related to tumors. If both assessments show a high probability, they label the fragments as tumor markers. This approach aims to improve the accuracy of cancer detection through a simple blood test.
Published: 2025-08-07
Upcycling Plastic Wastes into Graphites, Graphenes and Graphitic Carbons, for Electrochemical Energy Storage Devices
Plastic waste can be turned into useful materials like graphite and graphitic carbons using special solid additives. A new method helps process large amounts of plastic by improving how oxygen moves during the process. This allows for a much higher yield of usable material compared to older methods. The resulting graphite is very pure and can be made at lower temperatures, making it suitable for high-performance energy storage devices. This new type of graphite works well as an anode in lithium-ion batteries and other energy storage systems.
Published: 2025-08-07
LIVE SURGICAL AID FOR BRAIN TUMOR RESECTION USING AUGMENTED REALITY AND DEEP LEARNING
A new system uses augmented reality to help doctors during brain tumor surgeries. It stores 3D scans of the patient's brain, including images of the tumor and blood vessels. Cameras capture real-time images of the brain while the surgery is happening. Advanced computer programs analyze these images to identify and outline the tumor and nearby blood vessels. This information is then displayed in augmented reality, helping surgeons see exactly where to operate.
Published: 2025-08-07 Assignee: HUAWEI TECHNOLOGIES CO., LTD..
ANTENNA ARRAY AND APPARATUS
An antenna array consists of multiple smaller groups called subarrays, each containing several antenna elements. These elements are set up in a specific way to improve performance, with their spacing carefully controlled. The arrangement of these subarrays is designed so that they work together effectively, with one direction being perpendicular to another. This setup helps the antenna array operate better at certain frequencies. Overall, the design aims to enhance communication and signal quality.
Published: 2025-08-07 Assignee: QUALCOMM INCORPORATED.
TEMPORALLY CONSISTENT AND SEMANTICS GUIDED TEXT-BASED VIDEO EDITING GENERATIVE ARTIFICIAL INTELLIGENCE (AI) MODEL WITH IMPROVED INITIALIZATION
A new method allows users to edit videos using text descriptions. First, it takes a video and a written prompt from the user. Then, it analyzes the video to create a special representation of it. Next, some noise is added to this representation, which helps in making changes based on the video content. Finally, an artificial intelligence model uses the noisy representation and the text prompt to modify the video accordingly.