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Assignee profile:

LEICA MICROSYSTEMS CMS GMBH

City:

Wetzlar

Country:

Germany

Published Applications:

526

Last publication date:

2025-04-03

Patent Grants:

497

Last grant date:

2025-06-03

Quarterly LEICA MICROSYSTEMS CMS GMBH Patent Applications

Top Inventors for applications by LEICA MICROSYSTEMS CMS GMBH

These are the the leading inventors for applications assigned to LEICA MICROSYSTEMS CMS GMBH:

Werner KNEBEL 63 Kronau, Germany
Volker Seyfried 44 Nussloch, Germany
Holger Birk 36 Meckesheim, Germany
Bernd Widzgowski 34 Dossenheim, Germany

Florian Fahrbach 32 Mannheim, Germany
Christian Schumann 31 Lich, Germany
Hilmar GUGEL 22 Dossenheim, Germany
Frank Schreiber 17 Dossenheim, Germany

Heinrich ULRICH 17 Heidelberg, Germany
Rafael Storz 16 Heidelberg, Germany
Albrecht Weiss 14 Linden, Germany
Frank Olschewski 13 Heidelberg, Germany

Michael Ganser 13 Giessen, Germany
Falk SCHLAUDRAFF 13 Butzbach, Germany
Peter Euteneuer 12 Lahnau, Germany
Frank Sieckmann 12 Eppingen, Germany

Frank Sieckmann 12 Bochum, Germany
Kyra Moellmann 12 Trippstadt, Germany
Jonas FOELLING 10 Heidelberg, Germany
Marcus Dyba 10 Heidelberg, Germany

LEICA MICROSYSTEMS CMS GMBH 9 Wetzlar, Germany
Constantin KAPPEL 9 Schriesheim, Germany
Manfred Gilbert 9 Schoeffengrund, Germany
Vishnu Vardhan KRISHNAMACHARI 9 Seeheim-Jugenheim, Germany

Patric PELZER 8 Wetzlar, Germany
Roland SEIFERT 8 Heidelberg, Germany
Alexander WEISS 8 Linden, Germany
Florian Fahrbach 8 Heidelberg, Germany

Lars Friedrich 7 Weinheim, Germany
William C. HAY 7 Heppenheim, Germany
Andreas Hecker 7 Asslar, Germany
Falk Schlaudraff 6 Butzbach/Nieder-Weisel, Germany

Reiner Rygiel 6 Altrip, Germany
Wernher Fouquet 6 Mannheim, Germany
Thorsten KOESTER 6 Edingen-Neckarhausen, Germany
Kai WALTER 6 Schriesheim, Germany

Kai RITSCHEL 6 Wetzlar, Germany
Marcus Dyba 6 Mannheim, Germany
Frank Schreiber 6 Heidelberg, Germany
Ingo BOEHM 6 Heidelberg, Germany

Stefan CHRIST 5 Schoeffengrund, Germany
Volker Leimbach 5 Ludwigshafen, Germany
Ralf KRUEGER 5 Butzbach Griedel, Germany
Kai RITSCHEL 5 Heuchelheim, Germany

Arnold Mueller-Rentz 5 Brechen, Germany
Christian Schulz 5 Solms, Germany
Wolfgang Oestreicher 5 Mannheim, Germany
Benjamin DEISSLER 5 Butzbach, Germany

Shih-Jong James Lee 5 Bellevue, WA United States
Jose Miguel Serra Lleti 5 Wetzlar, Germany
Russell Bonaventura 5 Williamsville, NY United States
Patric Mrawek 5 Hassloch, Germany

Manuel KREMER 5 Leimen, Germany
Christian Schumann 5 Giessen, Germany
Claus Bender 5 Asslar-Werdorf, Germany
Jochen Sieber 4 Mannheim, Germany

Florian Hoffmann 4 Giessen, Germany
Ingo Böhm 4 Heidelberg, Germany
Jonas FOELLING 4 Freiburg, Germany
Johann Engelhardt 4 Bad Schoenborn, Germany

Felix NEUGART 4 Mannheim, Germany
Patric Mrawek 4 Neustadt, Germany
Frank Hecht 4 Wetzlar, Germany
Christian SCHUMANN 4 Wetzlar, Germany

Juergen Riedmann 4 Harthausen, Germany
Dirk-Oliver FEHRER 4 Bad Schoenborn, Germany
Ronja Capellmann 4 Wetzlar, Germany
Frank Hecht 4 Mannheim, Germany

Urban Liebel 4 Dielheim-Horrenberg, Germany
Martin Kubek 4 Driedorf, Germany
Hideki Sasaki 4 Bellevue, WA United States
Jonas Fölling 4 Heidelberg, Germany

Paul M. Harrison 3 Alden, NY United States
Gerhard Pfeifer 3 Solms, Germany
Gerhard Pfeifer 3 Wetzlar, Germany
Jasna Roeth 3 Solms, Germany

Andreas LOTTER 3 Wetzlar, Germany
Klaus Hermanns 3 Asslar, Germany
Oliver Schlicker 3 Wetzlar, Germany
Jochen Nickel 3 Mannheim, Germany

Lioba Kuschel 3 Mannheim, Germany
Mate BELJAN 3 Wetzlar, Germany
Juergen Schneider 3 Sinsheim, Germany
Dirk-Oliver Fehrer 3 Bad Schonborn, Germany

Tobias Bauer 3 Koenigstein, Germany
Benjamin DEISSLER 3 Wetzlar, Germany
Markus Weber 3 Wetzlar, Germany
Christian SCHULZ 3 Huettenberg, Germany

Volker SCHACHT 3 Marburg, Germany
Vishnu Vardhan Krishnamachari 3 Mannheim, Germany
Sebastian HITZLER 3 Hohenahr-Erda, Germany
Arnold Giske 3 Heidelberg, Germany

Florian ZIESCHE 3 Mannheim, Germany
Christian Woditschka 3 Wetzlar, Germany
Luis Alvarez 3 Wetzlar, Germany
Rafael STORZ 3 Bammental, Germany

Roland Seifert 3 Kassel, Germany
Frank Eisenkrämer 3 Biebertal, Germany
Malte Wachsmuth 2 Heidelberg, Germany
David Andrew Shoudy 2 Niskayuna, NY United States

Recent patent applications by LEICA MICROSYSTEMS CMS GMBH

LEICA MICROSYSTEMS CMS GMBH based in Wetzlar, DE has been assigned the rights to these inventions. The list includes both Pending Applications and Patent Grants:

#1 | 2025-04-03 ✅ Patent 12,320,967 granted on 2025-06-03

US20250110323A1

Physics

Positioning device for an imaging device and method

#2 | 2024-12-12 ✅ Patent 12,625,359 granted on 2026-05-12

US20240411123A1

Physics

METHOD FOR PROVIDING POSITION INFORMATION FOR RETRIEVING A TARGET POSITION IN A MICROSCOPIC SAMPLE, METHOD FOR EXAMINING AND/OR PROCESSING SUCH A TARGET POSITION AND MEANS FOR IMPLEMENTING THESE METHODS

#3 | 2024-09-12 ✅ Patent 12,430,723 granted on 2025-09-30

US20240303785A1

Physics

DATA PROCESSING APPARATUS AND METHOD FOR PROCESSING A DIGITAL IMAGE HAVING PHOTON ARRIVAL-TIME DATA

#4 | 2024-08-29 ✅ Patent 12,626,523 granted on 2026-05-12

US20240290117A1

Physics

PROCESSOR FOR LIFETIME-BASED UNMIXING IN FLUORESCENCE MICROSCOPY

#5 | 2024-08-15 ✅ Patent 12,510,743 granted on 2025-12-30

US20240272415A1

Physics

COMPUTER SYSTEM FOR DISPLAYING SAMPLE IMAGES, MICROSCOPE SYSTEM, AND METHOD THEREFOR

#6 | 2024-07-25 ✅ Patent 12,513,386 granted on 2025-12-30

US20240251151A1

Electricity

METHOD AND DEVICE FOR GENERATING A COMPOSITE IMAGE OF A SAMPLE

#7 | 2024-07-18 ✅ Patent 12,510,741 granted on 2025-12-30

US20240241359A1

Physics

METHOD FOR EXAMINING A FLUORESCENT SAMPLE, MICROSCOPE SYSTEM AND COMPUTER PROGRAM

#8 | 2024-06-27 ✅ Patent 12,482,074 granted on 2025-11-25

US20240212109A1

Physics

SYSTEMS AND METHODS FOR TRAINING A MACHINE-LEARNING ALGORITHM AND APPLICATION OF A MACHINE-LEARNING MODEL FOR DENOISING IMAGES

#9 | 2024-06-06 ✅ Patent 12,393,024 granted on 2025-08-19

US20240184104A1

Physics

OPTICAL SYSTEM FOR A MICROSCOPE

#10 | 2024-05-23 ✅ Patent 12,393,011 granted on 2025-08-19

US20240168274A1

Physics

Optical imaging system, methods, systems, and computer programs

#11 | 2024-04-11 ✅ Patent 12,474,558 granted on 2025-11-18

US20240118527A1

Physics

FLUORESCENCE MICROSCOPY FOR A PLURALITY OF SAMPLES

#12 | 2024-03-21 ✅ Patent 12,585,566 granted on 2026-03-24

US20240095145A1

Physics

MAINTENANCE PREDICTION FOR MODULES OF A MICROSCOPE

#13 | 2024-02-29 ✅ Patent 12,347,527 granted on 2025-07-01

US20240071574A1

Physics

DATA STORAGE DEVICE AND METHOD FOR STORING DATA

#14 | 2024-02-15 ✅ Patent 12,366,741 granted on 2025-07-22

US20240053596A1

Physics

CONTROL DEVICE FOR A MICROSCOPE

#15 | 2024-02-01 ✅ Patent 12,579,657 granted on 2026-03-17

US20240037755A1

Physics

IMAGING DEVICE AND METHOD

#16 | 2023-12-14 ✅ Patent 12,422,365 granted on 2025-09-23

US20230400411A1

Physics

CONTROLLER FOR AN IMAGING DEVICE AND METHOD

#17 | 2023-12-07 ✅ Patent 12,626,338 granted on 2026-05-12

US20230394632A1

Physics

METHOD AND IMAGE PROCESSING DEVICE FOR IMPROVING SIGNAL-TO-NOISE RATIO OF IMAGE FRAME SEQUENCES

#18 | 2023-11-30 ✅ Patent 12,609,267 granted on 2026-04-21

US20230386779A1

Electricity

SAMPLE HOLDER, LOADING DEVICE, AND METHOD FOR INSERTING A SAMPLE INTO A SAMPLE HOLDER

#19 | 2023-10-26 ✅ Patent 12,278,654 granted on 2025-04-15

US20230344447A1

Electricity

Method for compression of time tagged data from time correlated single photon counting

#20 | 2023-10-12 ✅ Patent 12,313,830 granted on 2025-05-27

US20230324662A1

Physics

Method for adjusting the illumination in a fluorescence microscope, and corresponding fluorescence microscope

#21 | 2023-10-05 ✅ Patent 12,474,560 granted on 2025-11-18

US20230314783A1

Physics

OPTICAL DEVICE, RETROFITTING SET AND METHOD FOR PRODUCING LIGHT SHEETS BY MEANS OF A REFLECTOR

#22 | 2023-10-05 ✅ Patent 12,650,584 granted on 2026-06-09

US20230314780A1

Physics

METHOD, OPTICAL APPARATUS AND RETROFIT KIT FOR PRODUCING LIGHT SHEETS BY MEANS OF A RETROREFLECTOR

#23 | 2023-09-21 ✅ Patent 12,644,803 granted on 2026-06-02

US20230296483A1

Physics

METHOD AND SYSTEM FOR EXTRACTING A PART OF A MICROSCOPIC SAMPLE

#24 | 2023-08-03 ✅ Patent 12,449,648 granted on 2025-10-21

US20230244069A1

Physics

INVERTED MICROSCOPE

#25 | 2023-07-27 ✅ Patent 11,885,950 granted on 2024-01-30

US20230236402A1

Physics

Light source module for a microscope

#26 | 2023-07-27 ✅ Patent 12,210,145 granted on 2025-01-28

US20230236401A1

Physics

Single-particle localization microscope

#27 | 2023-06-22 ✅ Patent 12,437,506 granted on 2025-10-07

US20230196725A1

Physics

IMAGE ANNOTATION SYSTEM AND METHOD

#28 | 2023-06-22 ✅ Patent 12,488,461 granted on 2025-12-02

US20230196566A1

Physics

IMAGE ANNOTATION SYSTEM AND METHOD

#29 | 2023-06-22 ✅ Patent 11,763,434 granted on 2023-09-19

US20230196531A1

Physics

Image processing system

#30 | 2023-06-22 ✅ Patent 12,625,357 granted on 2026-05-12

US20230196513A1

Physics

FLUORESCENCE MICROSCOPE SYSTEM AND METHOD

#31 | 2023-06-22 ✅ Patent 12,434,238 granted on 2025-10-07

US20230191404A1

Performing operations; transporting

IMAGING SYSTEM AND METHOD FOR IMAGING BIOLOGICAL SAMPLES

#32 | 2023-06-15 ✅ Patent 12,254,639 granted on 2025-03-18

US20230186483A1

Physics

Method for determining boundaries of a z-stack of images of an object, corresponding optical instrument and computer program therefor

#33 | 2023-06-15 ✅ Patent 12,422,659 granted on 2025-09-23

US20230185071A1

Physics

METHOD FOR CONTROLLING MICROSCOPIC IMAGING AND CORRESPONDING MICROSCOPE CONTROL ARRANGEMENT AND MICROSCOPE

#34 | 2023-06-15 ✅ Patent 12,596,242 granted on 2026-04-07

US20230185068A1

Physics

INCLINED-PLANE MICROSCOPE HAVING IMPROVED COLLECTION EFFICIENCY

#35 | 2023-06-15 ✅ Patent 12,629,214 granted on 2026-05-19

US20230181262A1

Human necessities

Devices and Methods for Imaging and Surgical Applications

#36 | 2023-06-08 ✅ Patent 12,339,229 granted on 2025-06-24

US20230175963A1

Physics

METHOD OF ANALYZING A MIXED FLUORESCENCE RESPONSE OF A PLURALITY OF FLUOROPHORES, FLUORESCENCE ANALYZER, FLUORESCENCE MICROSCOPE AND COMPUTER PROGRAM

#37 | 2023-06-08 ✅ Patent 12,553,770 granted on 2026-02-17

US20230175886A1

Physics

METHOD AND APPARATUS CONFIGURED TO COUNT N-PHOTON EVENTS

#38 | 2023-05-25 ✅ Patent 12,443,025 granted on 2025-10-14

US20230161146A1

Physics

METHOD AND DEVICE FOR EXAMINING MICROSCOPE SPECIMENS USING OPTICAL MARKERS

#39 | 2023-05-25 ✅ Patent 12,436,373 granted on 2025-10-07

US20230161143A1

Physics

FLUORESCENCE MICROSCOPE SYSTEM AND METHOD

#40 | 2023-05-18 ✅ Patent 12,449,647 granted on 2025-10-21

US20230152562A1

Physics

LIGHT SHEET MICROSCOPE AND METHOD FOR MANIPULATING A TARGET AREA OF A SAMPLE

#41 | 2023-05-11 ✅ Patent 12,253,726 granted on 2025-03-18

US20230147321A1

Physics

System and method for coupling an optical beam into a light receiver

#42 | 2023-04-27 ✅ Patent 12,038,380 granted on 2024-07-16

US20230129462A1

Physics

Fluorescence microscope and method for imaging an object

#43 | 2023-04-27 ✅ Patent 12,518,355 granted on 2026-01-06

US20230126326A1

Physics

TRAINING A DENOISING MODEL FOR A MICROSCOPE

#44 | 2023-04-06 ✅ Patent 12,326,549 granted on 2025-06-10

US20230104545A1

Physics

OPTICAL ASSEMBLY FOR AN INCLINED-PLANE MICROSCOPE FOR IMPROVING THE RESOLUTION

#45 | 2023-03-16 ✅ Patent 11,762,182 granted on 2023-09-19

US20230085581A1

Physics

SPIM microscope with a sequential light sheet

#46 | 2023-03-02 ✅ Patent 12,631,888 granted on 2026-05-19

US20230067865A1

Physics

OPTICAL APPARATUS

#47 | 2023-03-02 ✅ Patent 12,638,396 granted on 2026-05-26

US20230063660A1

Physics

PROCESSOR FOR DEMIXING A FLUORESCENT-LIGHT INPUT SIGNAL, FLUORESCENCE MICROSCOPE AND FLUORESCENCE MICROSCOPY METHOD

#48 | 2023-02-23 ✅ Patent 11,940,718 granted on 2024-03-26

US20230056633A1

Physics

Optical assembly having a movable lens unit

#49 | 2023-02-02 ✅ Patent 12,422,671 granted on 2025-09-23

US20230035107A1

Physics

OBLIQUE PLANE MICROSCOPE AND METHOD FOR CORRECTING AN ABERRATION IN AN OBLIQUE PLANE MICROSCOPE

#50 | 2023-01-12 ✅ Patent 12,111,454 granted on 2024-10-08

US20230008453A1

Physics

Laser scanning microscope and method for determining a position of a fluorophore

#51 | 2022-12-15 ✅ Patent 12,416,797 granted on 2025-09-16

US20220397753A1

Physics

MICROSCOPE AND METHOD FOR EXAMINING A SAMPLE

#52 | 2022-12-08 ✅ Patent 12,449,649 granted on 2025-10-21

US20220390732A1

Physics

MICROSCOPE FOR TRANSMITTED LIGHT CONTRASTING

#53 | 2022-12-08 ✅ Patent 12,332,417 granted on 2025-06-17

US20220390730A1

Physics

OPTICAL SYSTEM FOR A LIGHT SHEET MICROSCOPE

#54 | 2022-11-24 ✅ Patent 12,019,229 granted on 2024-06-25

US20220373778A1

Physics

Illumination arrangement for a microscope, microscope and method for illuminating a sample volume in a microscope

#55 | 2022-11-24 ✅ Patent 12,571,736 granted on 2026-03-10

US20220373464A1

Physics

CONTROL SYSTEM AND METHOD FOR DETERMINING AN ILLUMINATION INTENSITY IN A FLUORESCENCE MICROSCOPE AND CORRESPONDING MICROSCOPE SYSTEM

#56 | 2022-11-10 ✅ Patent 12,260,529 granted on 2025-03-25

US20220357558A1

Physics

Image processing apparatus and method for enhancing a phase distribution

#57 | 2022-11-03 ✅ Patent 11,953,407 granted on 2024-04-09

US20220349783A1

Physics

Laboratory system particularly for use in microscopy

#58 | 2022-11-03 ✅ Patent 11,826,760 granted on 2023-11-28

US20220347691A1

Performing operations; transporting

Self-contained slide processing unit for biological specimens

#59 | 2022-10-27 ✅ Patent 12,243,194 granted on 2025-03-04

US20220343467A1

Physics

STED microscopy method with improved signal to noise ratio in low photon count imaging conditions

#60 | 2022-10-27 ✅ Patent 12,136,184 granted on 2024-11-05

US20220343463A1

Physics

Changing the size of images by means of a neural network

#61 | 2022-10-06 ✅ Patent 12,228,716 granted on 2025-02-18

US20220317429A1

Physics

Microscope and method for imaging an object using a microscope

#62 | 2022-09-29 ✅ Patent 12,041,340 granted on 2024-07-16

US20220311933A1

Electricity

Controller and method for providing an operational setting of an imaging device

#63 | 2022-09-29 ✅ Patent 12,517,339 granted on 2026-01-06

US20220308329A1

Physics

MICROSCOPE FOR EXAMINATION OF A SAMPLE AND CORRESPONDING METHOD OF OPERATING SUCH A MICROSCOPE

#64 | 2022-09-08 ✅ Patent 12,277,719 granted on 2025-04-15

US20220284604A1

Physics

Multispectral microscope system and method for registering first and second images by means thereof

#65 | 2022-09-08 ✅ Patent 12,228,719 granted on 2025-02-18

US20220283422A1

Physics

Device and method for imaging an object

#66 | 2022-09-01 ✅ Patent 12,106,454 granted on 2024-10-01

US20220277441A1

Physics

Image processing apparatus and method for use in an autofocus system

#67 | 2022-09-01 ✅ Patent 12,038,357 granted on 2024-07-16

US20220276136A1

Physics

Method for obtaining dissectates microscopic sample, laser microdissection system and computer program

#68 | 2022-08-11 ✅ Patent 12,272,161 granted on 2025-04-08

US20220254177A1

Physics

System and method for processing biology-related data and a microscope

#69 | 2022-08-11 ✅ Patent 12,315,119 granted on 2025-05-27

US20220253983A1

Physics

Signal processing apparatus and method for enhancing a digital input signal

#70 | 2022-08-04 ✅ Patent 12,026,191 granted on 2024-07-02

US20220245188A1

Physics

System and method for processing biology-related data, a system and method for controlling a microscope and a microscope

#71 | 2022-08-04 ✅ Patent 12,496,586 granted on 2025-12-16

US20220241792A1

Performing operations; transporting

MICROPLATE FOR CONTAINING A PLURALITY OF SAMPLES

#72 | 2022-07-21 ✅ Patent 11,960,518 granted on 2024-04-16

US20220229862A1

Physics

System and method for processing biology-related data, a system and method for controlling a microscope and a microscope

#73 | 2022-07-21 ✅ Patent 12,306,391 granted on 2025-05-20

US20220229279A1

Physics

Microscope and method for operating a microscope

#74 | 2022-07-07 ✅ Patent 11,928,819 granted on 2024-03-12

US20220214533A1

Physics

Method, processing system and system for approximating image data

#75 | 2022-06-30 ✅ Patent 11,500,189 granted on 2022-11-15

US20220206281A1

Physics

Light sheet microscope and method for determining the refractive indices of objects in the specimen space

#76 | 2022-06-23 ✅ Patent 12,306,103 granted on 2025-05-20

US20220196555A1

Physics

Fluorescence microscope and method for imaging a sample

#77 | 2022-06-23 ✅ Patent 11,650,158 granted on 2023-05-16

US20220196554A1

Physics

Fluorescence scanning microscope and method for imaging a sample

#78 | 2022-06-23 ✅ Patent 12,522,791 granted on 2026-01-13

US20220195363A1

Chemistry; metallurgy

MICROPLATE ASSEMBLY AND METHOD FOR TRANSFERRING SAMPLE BY MEANS OF A MICROPLATE ASSEMBLY

#79 | 2022-06-02 ✅ Patent 12,326,550 granted on 2025-06-10

US20220171176A1

Physics

DEVICE FOR HOLDING SPECIMENS IN A MICROSCOPE

#80 | 2022-05-05 ✅ Patent 12,020,405 granted on 2024-06-25

US20220138910A1

Physics

Methods and systems for training convolutional neural networks

#81 | 2022-05-05 ✅ Patent 12,625,355 granted on 2026-05-12

US20220137385A1

Physics

MICROSCOPE AND METHOD FOR MICROSCOPIC EXAMINATION OF LARGE SAMPLES

#82 | 2022-05-05 ✅ Patent 11,874,207 granted on 2024-01-16

US20220136936A1

Physics

Method for laser microdissection, laser microdissection system and computer program

#83 | 2022-04-28 ✅ Patent 12,181,652 granted on 2024-12-31

US20220128809A1

Physics

Method for generating an image by means of a microscope and corresponding microscope

#84 | 2022-04-14 ✅ Patent 12,253,663 granted on 2025-03-18

US20220113531A1

Physics

Control device for a microscope

#85 | 2022-04-14 ✅ Patent 12,124,019 granted on 2024-10-22

US20220113523A1

Physics

Microscope with a wide-field illuminator and a common detection objective for a camera detector and a point detector

#86 | 2022-03-24 ✅ Patent 11,933,972 granted on 2024-03-19

US20220091411A1

Physics

Optical system for a microscope

#87 | 2022-02-24 ✅ Patent 11,797,337 granted on 2023-10-24

US20220058052A1

Physics

Data processing management methods for imaging applications

#88 | 2022-02-24 ✅ Patent 11,933,960 granted on 2024-03-19

US20220057618A1

Physics

Microscope system with an input unit for simultaneously adjusting at least three adjustment parameters by means of an input pointer that is positionable in an input area

#89 | 2022-02-17 ✅ Patent 11,972,542 granted on 2024-04-30