Institut Curie

METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF

#2 | 2026-05-21

US20260137709A1

QUINOLINE DERIVATIVES FOR USE IN THE TREATMENT OF INFLAMMATION DISEASES

#3 | 2026-02-05

US20260035348A1

PHENYL-N-QUINOLINE DERIVATIVES FOR TREATING A RNA VIRUS INFECTION

#4 | 2025-10-02

US20250304915A1

Myeloid Cells Overexpressing BCL2

#5 | 2025-10-02

US20250304718A1

HER2 SINGLE DOMAIN ANTIBODY AND USES THEREOF

#6 | 2025-09-04

US20250275994A1

Quinoline Derivatives For Use In The Treatment Of Inflammation Diseases

#7 | 2025-07-03

US20250213614A1

Modified RELA Protein for Inducing Interferon Expression and Engineered Immune Cells with Improved Interferon Expression

#8 | 2025-06-19

US20250197945A1

Method for Detecting Microsatellite Instability in Cancer Patient

#9 | 2025-05-20 ✅ Patent 12,308,126 granted on 2025-05-20

US18626942

Device and method for predicting a relapse of a cancer for a patient

#10 | 2025-05-01

US20250135232A1

SCANNING DYNAMIC DEVICE FOR MINIBEAMS PRODUCTION

#11 | 2025-03-27

US20250100971A1

IN VITRO OR EX VIVO METHODS FOR SCREENING A QUINOLINE DERIVATIVE

#12 | 2025-01-23

US20250029678A1

METHOD AND DEVICE FOR DETERMINING AND QUANTIFYING MODES OF ACTIVATION OF BIOLOGICAL PATHWAYS IN INDIVIDUAL CELLS

#13 | 2025-01-09 ✅ Patent 12,371,471 granted on 2025-07-29

US20250011389A1

IMMUNE CELLS DEFECTIVE FOR SUV39H1

#14 | 2024-11-28 ✅ Patent 12,152,077 granted on 2024-11-26

US20240392010A1

IMMUNOTHERAPY TARGETING TUMOR NEOANTIGENIC PEPTIDES

#15 | 2024-11-07

US20240371520A1

Prediction of BRCAness/Homologous Recombination Deficiency of Breast Tumors on Digitalized Slides

#16 | 2024-10-17

US20240343716A1

COMPOUNDS FOR PREVENTING, INHIBITING, OR TREATING CANCER, AIDS AND/OR PREMATURE AGING

#17 | 2024-09-19 ✅ Patent 12,479,802 granted on 2025-11-25

US20240308964A1

PHENYL-N-QUINOLINE DERIVATIVES FOR TREATING A RNA VIRUS INFECTION

#18 | 2024-08-15 ✅ Patent 12,640,232 granted on 2026-05-26

US20240274233A1

CELL-FREE DETECTION OF METHYLATED PROSTATE TUMOUR

#19 | 2024-08-15 ✅ Patent 12,640,231 granted on 2026-05-26

US20240274232A1

CELL-FREE DETECTION OF METHYLATED BREAST TUMOR

#20 | 2024-08-15

US20240269282A1

Methods for the Treatment of Cancer, Inflammatory Diseases and Autoimmune Diseases

#21 | 2024-07-11 ✅ Patent 12,371,741 granted on 2025-07-29

US20240229122A1

Method for Detecting a Mutation in a Microsatellite Sequence

#22 | 2024-06-20

US20240201192A1

FOLR2+ MACROPHAGES AND ANTI-TUMOR IMMUNITY

#23 | 2024-06-06

US20240182422A1

PREPARATION METHOD OF QUINOLINE DERIVATIVE COMPOUNDS

#24 | 2024-03-28

US20240101616A1

DAP10/12 BASED CARS ADAPTED FOR RUSH

#25 | 2024-03-14

US20240084354A1

MEANS AND METHODS FOR REGULATING INTRACELLULAR TRAFFICKING OF SECRETORY OR CELL MEMBRANE-ANCHORED PROTEINS OF INTEREST

#26 | 2024-03-14 ✅ Patent 12,622,926 granted on 2026-05-12

US20240082372A1

IMMUNOTHERAPY TARGETING TUMOR NEOANTIGENIC PEPTIDES

#27 | 2024-02-01

US20240033366A1

FUNCTIONALIZED SHIGA TOXIN B-SUBUNIT (STxB) PROTEINS AND CONJUGATES THEREOF

#28 | 2024-01-18 ✅ Patent 12,252,517 granted on 2025-03-18

US20240018197A1

Hook fusion protein for regulating the cellular trafficking of a target protein

#29 | 2024-01-04

US20240002776A1

DEVICE FOR PROVIDING A LIQUID MEDIUM WITH A CONTROLLED FLOW RATE AND WITH A CONTROLLED DISSOLVED GAS CONCENTRATION

#30 | 2023-09-28

US20230303974A1

Immune Cells Defective for SOCS1

#31 | 2023-09-28 ✅ Patent 12,594,302 granted on 2026-04-07

US20230302050A1

Single Domain Antibodies and Their Use in Cancer Therapies

#32 | 2023-09-21

US20230293478A1

NITROGEN-CONTAINING ANALOGS OF SALINOMYCIN FOR USE IN ACUTE MYELOID LEUKEMIA

#33 | 2023-07-13

US20230220480A1

IRON-SCORE AND IN VITRO METHOD FOR IDENTIFYING HIGH RISK DLBCL SUBJECTS AND THERAPEUTIC USES AND METHODS

#34 | 2023-07-13

US20230218605A1

AMORPHOUS SOLID DISPERSION OF 8-CHLORO-N-(4-(TRIFLUOROMETHOXY)PHENYL)QUINOLIN-2-AMINE

#35 | 2023-07-06

US20230212243A1

Neoantigenic Epitopes Associated with SF3B1 Mutations

#36 | 2023-06-15

US20230184775A1

KINDLIN-1 AS A MARKER OF SENSITIVITY TO EGFR/RAS PATHWAY INHIBITORS

#37 | 2023-06-15

US20230183675A1

Synthetic Single Domain Library

#38 | 2023-04-20

US20230117652A1

Method for Detecting a Mutation in a Microsatellite Sequence

#39 | 2023-04-06

US20230107291A1

Method for Identifying Functional Disease-Specific Regulatory T Cells

#40 | 2023-04-06 ✅ Patent 12,617,756 granted on 2026-05-05

US20230106420A1

ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION

#41 | 2023-03-02

US20230067676A1

CO-CRYSTALS AND SALTS OF 8-CHLORO-N-(4-(TRIFLUOROMETHOXY)PHENYL)QUINOLIN-2-AMINE

#42 | 2022-12-22

US20220401539A1

Immunotherapy Targeting Tumor Neoantigenic Peptides

#43 | 2022-12-15

US20220396840A1

IRON-SCORE AND IN VITRO METHOD FOR IDENTIFYING MANTLE CELL LYMPHOMA (MCL) SUBJECTS AND THERAPEUTIC USES AND METHODS

#44 | 2022-11-10 ✅ Patent 12,247,018 granted on 2025-03-11

US20220356175A1

Aryl-n-aryl derivatives for treating a RNA virus infection

#45 | 2022-10-06 ✅ Patent 12,202,804 granted on 2025-01-21

US20220315535A1

In vitro or ex vivo methods for screening a quinoline derivative

#46 | 2022-07-28 ✅ Patent 12,527,854 granted on 2026-01-20

US20220233673A1

METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STxB) MONOMERS AND OLIGOMERS, AND USES THEREOF

#47 | 2022-06-23 ✅ Patent 12,611,445 granted on 2026-04-28

US20220193198A1

Interleukin-2 Variants with Modified Biological Activity

#48 | 2022-05-12

US20220145406A1

BIOMARKERS, AND USES IN TREATMENT OF VIRAL INFECTIONS, INFLAMMATIONS, OR CANCER

#49 | 2022-04-28

US20220127253A1

COMPOUNDS FOR PREVENTING, INHIBITING, OR TREATING CANCER, AIDS AND/OR PREMATURE AGING

#50 | 2022-04-28 ✅ Patent 12,414,991 granted on 2025-09-16

US20220125923A1

NOVEL AZOBENZENE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THERAPEUTIC TREATMENT ASSOCIATED WITH IONIZING RADIATIONS

#51 | 2022-03-10

US20220071985A1

QUINOLINE DERIVATIVES FOR USE IN THE TREATMENT OR PREVENTION OF CANCER

#52 | 2022-03-03 ✅ Patent 12,618,832 granted on 2026-05-05

US20220065849A1

IDENTIFICATION OF COGNATE PAIRS OF LIGANDS AND RECEPTORS

#53 | 2022-02-10 ✅ Patent 11,285,176 granted on 2022-03-29

US20220040235A1

Immune cells defective for Suv39h1

#54 | 2022-01-27 ✅ Patent 11,992,499 granted on 2024-05-28

US20220023324A1

Quinoline derivatives for use in the treatment of inflammation diseases

#55 | 2021-11-11 ✅ Patent 11,866,484 granted on 2024-01-09

US20210347855A1

Synthetic single domain antibody

#56 | 2021-10-07 ✅ Patent 12,084,422 granted on 2024-09-10

US20210309611A1

Phenyl-n-quinoline derivatives for treating a RNA virus infection

#57 | 2021-09-30 ✅ Patent 11,739,073 granted on 2023-08-29

US20210300871A1

Aryl-n-aryl derivatives for treating a RNA virus infection

#58 | 2021-08-12

US20210246518A1

Method for Detecting in a Cell RNA-Protein Interaction

#59 | 2021-07-29 ✅ Patent 12,415,781 granted on 2025-09-16

US20210230105A1

COMPOUNDS WITH BIGUANIDYL RADICAL AND USES THEREOF

#60 | 2021-06-03 ✅ Patent 11,406,631 granted on 2022-08-09

US20210161887A1

Hydrazone derivatives for preventing or treating EBV-related cancers

#61 | 2021-04-29 ✅ Patent 12,421,206 granted on 2025-09-23

US20210122732A1

ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION

#62 | 2021-03-25 ✅ Patent 11,649,211 granted on 2023-05-16

US20210087145A1

Use of quinoline derivatives for the treatment of inflammatory diseases

#63 | 2021-02-18 ✅ Patent 11,649,210 granted on 2023-05-16

US20210047273A1

Use of quinoline derivatives for the treatment of inflammatory diseases

#64 | 2021-01-28 ✅ Patent 12,584,165 granted on 2026-03-24

US20210024984A1

Method for Identifying One or More Mutations in a Hotspot Mutation Sequence

#65 | 2020-09-17

US20200291466A1

Method for Detecting a Mutation in a Microsatellite Sequence

#66 | 2020-08-06 ✅ Patent 10,947,491 granted on 2021-03-16

US20200247046A1

Print head of a printer, printer and printing method

#67 | 2020-07-30 ✅ Patent 11,427,566 granted on 2022-08-30

US20200239444A1

Compounds useful for treating cancer

#68 | 2020-06-04 ✅ Patent 11,162,095 granted on 2021-11-02

US20200172901A1

Use of a combination of Dbait molecule and PARP inhibitors to treat cancer

#69 | 2020-06-04 ✅ Patent 11,014,918 granted on 2021-05-25

US20200172525A1

Compounds and pharmaceutical compositions containing at least one of the compounds

#70 | 2020-06-04 ✅ Patent 11,097,275 granted on 2021-08-24

US20200171499A1

Device for manipulation of packets in micro-containers, in particular in microchannels

#71 | 2020-06-04 ✅ Patent 11,622,978 granted on 2023-04-11

US20200171090A1

Immune cells defective for SUV39H1

#72 | 2020-04-23 ✅ Patent 11,162,951 granted on 2021-11-02

US20200124611A1

Membrane-impermeant fluorogenic chromophores

#73 | 2020-01-09 ✅ Patent 10,927,179 granted on 2021-02-23

US20200010556A1

Human follicle-stimulating hormone receptor (FSHR) extracellular domain antibodies and methods of use thereof

#74 | 2019-12-19 ✅ Patent 10,981,874 granted on 2021-04-20

US20190382347A1

Use of quinoline derivatives for the treatment of inflammatory diseases

#75 | 2019-12-05 ✅ Patent 10,968,281 granted on 2021-04-06

US20190367635A1

Anti-LSP1 antibody

#76 | 2019-12-05 ✅ Patent 10,576,103 granted on 2020-03-03

US20190365807A1

Immune cells defective for SUV39H1

#77 | 2019-10-24 ✅ Patent 10,975,063 granted on 2021-04-13

US20190322656A1

Compound, and production method thereof, and methods of treatment using the compound

#78 | 2019-10-17 ✅ Patent 10,765,758 granted on 2020-09-08

US20190314511A1

Optimized in vivo delivery system with endosomolytic agents for nucleic acid conjugates

#79 | 2019-09-26 ✅ Patent 11,209,421 granted on 2021-12-28

US20190293629A1

Cytidine deaminase expression level in cancer as a new therapeutic target

#80 | 2019-08-22 ✅ Patent 12,300,356 granted on 2025-05-13

US20190256921A1

Cell-free detection of methylated tumour DNA

#81 | 2019-03-28 ✅ Patent 10,821,128 granted on 2020-11-03

US20190091254A1

Treatment of cancer by systemic administration of Dbait molecules

#82 | 2019-02-21 ✅ Patent 11,236,300 granted on 2022-02-01

US20190055511A1

Microfluidic device for controlling the geometry of living bodies

#83 | 2019-01-31 ✅ Patent 10,969,389 granted on 2021-04-06

US20190033311A1

Method to monitor and quantify interphase nuclear envelope rupture events

#84 | 2019-01-24 ✅ Patent 10,654,813 granted on 2020-05-19

US20190022037A1

Chemical molecules that inhibit the slicing mechanism for treating diseases resulting from splicing anomalies

#85 | 2018-12-27 ✅ Patent 11,536,724 granted on 2022-12-27

US20180372754A1

Bladder cancer biomarker proteins

#86 | 2018-12-20 ✅ Patent 10,563,197 granted on 2020-02-18

US20180362972A1

Use of a combination of Dbait molecule and PARP inhibitors to treat cancer

#87 | 2018-11-29 ✅ Patent 10,683,284 granted on 2020-06-16

US20180339981A1

Compounds for preventing, inhibiting, or treating cancer, aids and/or premature aging

#88 | 2018-11-15 ✅ Patent 11,014,977 granted on 2021-05-25

US20180327481A1

Synthetic single domain antibody

#89 | 2018-08-09 ✅ Patent 10,717,724 granted on 2020-07-21

US20180222888A1

Compounds useful for treating cancer

#90 | 2018-07-19 ✅ Patent 10,661,274 granted on 2020-05-26

US20180200714A1

Composite woven fluidic device

#91 | 2018-07-12 ✅ Patent 10,780,435 granted on 2020-09-22

US20180193833A1

Fluidic devices with at least one actionnable fiber

#92 | 2018-05-10 ✅ Patent 10,538,485 granted on 2020-01-21

US20180127353A1

Compounds for use as therapeutic agents affecting P53 expression and/or activity

#93 | 2018-02-01 ✅ Patent 10,718,770 granted on 2020-07-21

US20180031557A1

Methods for screening compounds for treating or preventing a viral infection or a virus-related condition

#94 | 2018-02-01 ✅ Patent 10,030,068 granted on 2018-07-24

US20180030117A1

Synthetic single domain antibody

#95 | 2018-02-01 ✅ Patent 10,329,317 granted on 2019-06-25

US20180030078A1

Quinoline derivative for use in the treatment and prevention of viral infections

#96 | 2018-02-01 ✅ Patent 10,806,729 granted on 2020-10-20

US20180028522A1

Quinoline derivatives for use in the treatment or prevention of viral infection

#97 | 2018-01-25 ✅ Patent 11,248,240 granted on 2022-02-15

US20180023091A1

Method for inducing targeted meiotic recombinations

#98 | 2017-11-23 ✅ Patent 10,809,261 granted on 2020-10-20

US20170336414A1

Prediction of recurrence for bladder cancer by a protein signature in tissue samples

#99 | 2017-10-19 ✅ Patent 10,363,317 granted on 2019-07-30

US20170298089A1

Optimized in vivo delivery system with endosomolytic agents for nucleic acid conjugates

#100 | 2017-09-14 ✅ Patent 11,149,316 granted on 2021-10-19

US20170260588A1