Santen Pharmaceutical Co., Ltd. based in Osaka, JP has been assigned the rights to these inventions. The list includes both Pending Applications and Patent Grants:

#1 | 2025-07-24

US20250235439A1

Human necessities

PHARMACEUTICAL FORMULATIONS COMPRISING A PYRIDYLAMINOACETIC ACID COMPOUND

#2 | 2024-01-25 ✅ Patent 12,636,367 granted on 2026-05-26

US20240024484A1

Human necessities

PHARMACEUTICAL COMPOSITION CONTAINING PYRIDYLAMINOACETIC ACID COMPOUND

#3 | 2024-01-04 ✅ Patent 12,295,946 granted on 2025-05-13

US20240000763A1

Human necessities

Pharmaceutical formulations comprising a pyridylaminoacetic acid compound

#4 | 2023-11-09 ✅ Patent 12,611,509 granted on 2026-04-28

US20230355885A1

Human necessities

ACCURATE, PRECISE MICROLITER DOSING SYRINGE

#5 | 2023-09-07 ✅ Patent 12,290,511 granted on 2025-05-06

US20230277515A1

Human necessities

Pharmaceutical preparation containing pyridyl aminoacetic acid compound

#6 | 2023-06-22 ✅ Patent 11,951,098 granted on 2024-04-09

US20230190716A1

Human necessities

Therapeutic agent for meibomian dysfunction

#7 | 2023-05-11

US20230145529A1

Human necessities

SILVER SALT-CONTAINING OPHTHALMIC AQUEOUS COMPOSITION FILLED IN RESIN CONTAINER

#8 | 2023-03-23 ✅ Patent 12,005,063 granted on 2024-06-11

US20230087826A1

Human necessities

Medicament for preventing and/or treating dry eye

#9 | 2023-02-09

US20230040386A1

Human necessities

URSODEOXYCHOLIC ACID-CONTAINING AGENT FOR TREATING OR PREVENTING PRESBYOPIA

#10 | 2023-01-19

US20230015595A1

Human necessities

USE OF VALPROIC ACID FOR REDUCING POST-OPERATIVE SCARRING FOLLOWING A GLAUCOMA SURGERY

#11 | 2022-12-08 ✅ Patent 12,201,602 granted on 2025-01-21

US20220387372A1

Human necessities

Medicament comprising combination of sepetaprost and Rho-associated coiled-coil containing protein kinase inhibitor

#12 | 2022-05-17 ✅ Patent 11,331,322 granted on 2022-05-17

US17513593

Human necessities

Medicament for preventing and/or treating dry eye

#13 | 2022-03-31 ✅ Patent 11,419,880 granted on 2022-08-23

US20220096497A1

Human necessities

Ursodeoxycholic acid-containing agent for treating or preventing presbyopia

#14 | 2022-03-10

US20220072012A1

Human necessities

URSODEOXYCHOLIC ACID-CONTAINING AGENT FOR TREATING OR PREVENTING PRESBYOPIA

#15 | 2022-03-03 ✅ Patent 12,290,497 granted on 2025-05-06

US20220062209A1

Human necessities

Agent containing 4-phenylbutyrate, for preventing or treating presbyopia

#16 | 2022-02-24 ✅ Patent 11,793,798 granted on 2023-10-24

US20220054466A1

Human necessities

Pharmaceutical formulations comprising a pyridylaminoacetic acid compound

#17 | 2021-10-28 ✅ Patent 11,974,994 granted on 2024-05-07

US20210330654A1

Human necessities

Agent for treating or preventing glaucoma including a sulfonamide compound and another drug

#18 | 2021-07-29 ✅ Patent 11,872,271 granted on 2024-01-16

US20210228700A1

Human necessities

High-affinity anti-VEGF antibody KLHa505

#19 | 2021-06-17 ✅ Patent 11,707,577 granted on 2023-07-25

US20210178080A1

Human necessities

Accurate, precise microliter dosing syringe

#20 | 2021-05-06

US20210128601A1

Human necessities

THERAPEUTIC AGENT FOR DRY EYE CHARACTERIZED BY BEING APPLIED TO EYE OF DRY EYE PATIENT WEARING SOFT CONTACT LENS

#21 | 2021-03-04

US20210059931A1

Human necessities

METHOD AND COMPOSITION FOR TREATING OCULAR HYPERTENSION AND GLAUCOMA

#22 | 2021-01-14 ✅ Patent 12,510,536 granted on 2025-12-30

US20210011004A1

Physics

METHOD FOR CHANGING CONDITION OF EYELID OF HAIRLESS ANIMAL

#23 | 2020-12-10

US20200383957A1

Human necessities

DEPOT FORMULATIONS

#24 | 2020-11-12 ✅ Patent 11,439,652 granted on 2022-09-13

US20200352964A1

Human necessities

Ophthalmic aqueous composition

#25 | 2020-11-12

US20200352852A1

Human necessities

DEPOT FORMULATIONS

#26 | 2020-11-05 ✅ Patent 11,666,563 granted on 2023-06-06

US20200345713A1

Human necessities

Pharmaceutical preparation containing pyridyl aminoacetic acid compound

#27 | 2020-10-08 ✅ Patent 11,446,273 granted on 2022-09-20

US20200316009A1

Human necessities

Medicament comprising combination of sepetaprost and Rho-associated coiled-coil containing protein kinase inhibitor

#28 | 2020-09-17 ✅ Patent 11,197,849 granted on 2021-12-14

US20200289483A1

Human necessities

Pharmaceutical formulations comprising a pyridylaminoacetic acid compound

#29 | 2020-08-13 ✅ Patent 10,918,656 granted on 2021-02-16

US20200254000A1

Human necessities

Therapeutic agent for dry eye characterized by being applied to eye of dry eye patient wearing soft contact lens

#30 | 2020-07-09 ✅ Patent 11,166,974 granted on 2021-11-09

US20200215093A1

Human necessities

Ophthalmic solution comprising Diquafosol

#31 | 2020-07-02 ✅ Patent 11,331,311 granted on 2022-05-17

US20200206200A1

Human necessities

Prophylactic and/or therapeutic agent containing pyridylaminoacetic acid compound

#32 | 2020-06-18 ✅ Patent 10,940,144 granted on 2021-03-09

US20200188377A1

Human necessities

Drug containing pyridylaminoacetic acid compound

#33 | 2020-05-28 ✅ Patent 11,007,259 granted on 2021-05-18

US20200165330A1

Chemistry; metallurgy

High-affinity anti-VEGF antibody

#34 | 2020-05-14 ✅ Patent 11,324,829 granted on 2022-05-10

US20200147222A1

Human necessities

Antiseptic agent comprising meglumine or salt thereof

#35 | 2020-05-14 ✅ Patent 11,642,350 granted on 2023-05-09

US20200147098A1

Human necessities

Agent for preventing myopia, treating myopia, and/or preventing myopia progression comprising tiotropium as active ingredient

#36 | 2020-05-14 ✅ Patent 11,400,080 granted on 2022-08-02

US20200147056A1

Human necessities

Use of sirolimus to treat exudative age-related macular degeneration with persistent edema

#37 | 2020-03-19

US20200085804A1

Human necessities

AGENT FOR TREATING OR PREVENTING GLAUCOMA INCLUDING A SULFONAMIDE COMPOUND AND ANOTHER DRUG

#38 | 2020-02-13 ✅ Patent 10,765,750 granted on 2020-09-08

US20200046839A1

Human necessities

Pharmaceutical composition containing pyridylaminoacetic acid compound

#39 | 2019-11-28

US20190359577A1

Chemistry; metallurgy

[4-(1,3,3-TRIMETHYL-2-OXO-3,4-DIHYDRO-1H-QUINOXALIN-7-YL)PHENOXY]ETHYLOXY COMPOUND OR SALT THEREOF

#40 | 2019-11-28 ✅ Patent 11,285,081 granted on 2022-03-29

US20190358128A1

Human necessities

Sealed preparation container and use for same

#41 | 2019-11-14 ✅ Patent 11,013,731 granted on 2021-05-25

US20190343821A1

Human necessities

Intratumoral administration of sirolimus for treatment of prostate cancer

#42 | 2019-10-24 ✅ Patent 11,008,387 granted on 2021-05-18

US20190322732A1

Chemistry; metallurgy

Antibody inhibiting binding of VEGF to NRP1

#43 | 2019-08-22 ✅ Patent 11,612,590 granted on 2023-03-28

US20190255026A1

Human necessities

Therapeutic agent for meibomian dysfunction

#44 | 2019-04-11 ✅ Patent 10,435,379 granted on 2019-10-08

US20190106393A1

Chemistry; metallurgy

[4-(1,3,3-trimethyl-2-OXO-3,4-dihydro-1H-quinoxalin-7-yl)phenoxy]ethyloxy compound or salt thereof

#45 | 2019-04-11 ✅ Patent 10,702,511 granted on 2020-07-07

US20190105310A1

Human necessities

Pharmaceutical formulations comprising a pyridylaminoacetic acid compound

#46 | 2019-02-28 ✅ Patent 10,485,872 granted on 2019-11-26

US20190060459A1

Human necessities

Pharmaceutical composition containing pyridylaminoacetic acid compound

#47 | 2018-12-13 ✅ Patent 10,632,139 granted on 2020-04-28

US20180353531A1

Human necessities

Ophthalmic solution comprising diquafosol

#48 | 2018-12-13

US20180353518A1

Human necessities

OPHTHALMIC SOLUTIONS

#49 | 2018-11-01

US20180311152A1

Human necessities

LIQUID FORMULATIONS FOR TREATMENT OF DISEASES OR CONDITIONS

#50 | 2018-10-11 ✅ Patent 10,864,159 granted on 2020-12-15

US20180289618A1

Human necessities

Method and composition for treating ocular hypertension and glaucoma

#51 | 2018-09-27 ✅ Patent 10,166,217 granted on 2019-01-01

US20180271841A1

Human necessities

Fungal keratitis prophylactic or therapeutic agent

#52 | 2018-08-30

US20180246081A1

Physics

METHOD FOR CHANGING CONDITION OF EYELID OF HAIRLESS ANIMAL

#53 | 2018-05-03 ✅ Patent 10,682,340 granted on 2020-06-16

US20180117016A1

Human necessities

Depot formulations

#54 | 2018-02-15 ✅ Patent 11,090,296 granted on 2021-08-17

US20180042907A1

Human necessities

Sustained-release pharmaceutical composition

#55 | 2018-01-04 ✅ Patent 10,668,011 granted on 2020-06-02

US20180000729A1

Human necessities

Depot formulations

#56 | 2017-09-21

US20170266109A1

Human necessities

RAPAMYCIN FORMULATIONS AND METHODS OF THEIR USE

#57 | 2017-08-31

US20170247342A1

Chemistry; metallurgy

PRODUCTION METHOD FOR 3,3-DIMETHYL-3,4-DIHYDRO-1H-QUINOXALIN-2-ONE DERIVATIVE AND INTERMEDIATE FOR SAID PRODUCTION METHOD

#58 | 2017-03-23 ✅ Patent 9,902,698 granted on 2018-02-27

US20170081286A1

Chemistry; metallurgy

2-[[[2-[(Hydroxyacetyl)amino]-4-pyridinyl]methyl]thio]-N-[4-(trifluoromethoxy)phenyl]-3-pyridinecarboxamide benzenesulfonate, crystal of same, crystal polymorph thereof, and methods for production thereof

#59 | 2017-03-16 ✅ Patent 9,999,594 granted on 2018-06-19

US20170071852A1

Human necessities

Therapeutic or preventive agent for meibomian gland dysfunction or meibomian gland blockage

#60 | 2017-02-23

US20170049786A1

Human necessities

MTOR PATHWAY INHIBITORS FOR TREATING OCULAR DISORDERS

#61 | 2017-01-26 ✅ Patent 10,071,113 granted on 2018-09-11

US20170020910A1

Human necessities

Ophthalmic solution comprising diquafosol

#62 | 2017-01-26

US20170020809A1

Human necessities

LIQUID FORMULATIONS FOR TREATMENT OF DISEASES OR CONDITIONS

#63 | 2016-11-17 ✅ Patent 10,206,815 granted on 2019-02-19

US20160331587A1

Human necessities

Injector for intraocular lens

#64 | 2016-11-10 ✅ Patent 9,943,510 granted on 2018-04-17

US20160324838A1

Human necessities

Pharmaceutical formulations comprising a pyridylaminoacetic acid compound

#65 | 2016-11-03 ✅ Patent 10,149,908 granted on 2018-12-11

US20160317664A1

Human necessities

Pharmaceutical composition containing pyridylaminoacetic acid compound

#66 | 2016-10-20

US20160303093A1

Human necessities

RAPAMYCIN FORMULATIONS AND METHODS OF THEIR USE

#67 | 2016-09-01 ✅ Patent 9,546,140 granted on 2017-01-17

US20160251314A1

Chemistry; metallurgy

2-[[[2-[(hydroxyacetyl)amino]-4-pyridinyl]methyl]thio]-N[4-(trifluoromethoxy)phenyl]-3-pyridinecarboxamide benzenesulfonate, crystal of same, crystal polymorph thereof, and methods for production thereof

#68 | 2016-07-14 ✅ Patent 9,676,703 granted on 2017-06-13

US20160200690A1

Chemistry; metallurgy

Production method for 3,3-dimethyl-3,4-dihydro-1H-quinoxalin-2-one derivative and intermediate for said production method

#69 | 2016-04-21

US20160106757A1

Human necessities

OPHTHALMIC SOLUTIONS

#70 | 2016-01-14 ✅ Patent 9,579,309 granted on 2017-02-28

US20160008333A1

Human necessities

Prophylactic or therapeutic agent for posterior ocular disease containing tetrahydropyranylaminocyclopentylcarbonyltetrahydropyridopyridine derivative as effective ingredient

#71 | 2015-11-19 ✅ Patent 9,987,128 granted on 2018-06-05

US20150327992A1

Human necessities

Intraocular lens injector

#72 | 2015-10-15 ✅ Patent 9,359,328 granted on 2016-06-07

US20150291560A1

Chemistry; metallurgy

2-[[[2-[(hydroxyacetyl)amino]-4-pyridinyl]methyl]thio]-N-[4-(trifluoromethoxy)phenyl]-3-pyridinecarboxamide benzenesulfonate, crystal of same, crystal polymorph thereof, and methods for production thereof

#73 | 2015-10-01 ✅ Patent 9,827,139 granted on 2017-11-28

US20150272779A1

Human necessities

Intraocular lens injector

#74 | 2015-09-24 ✅ Patent 9,452,156 granted on 2016-09-27

US20150265581A1

Human necessities

Formulations and methods for vascular permeability-related diseases or conditions

#75 | 2015-09-03 ✅ Patent 9,539,204 granted on 2017-01-10

US20150245994A1

Human necessities

Therapeutic or preventive agent for meibomian gland dysfunction or meibomian gland blockage

#76 | 2015-07-16 ✅ Patent 9,415,038 granted on 2016-08-16

US20150196541A1

Human necessities

Pharmaceutical formulations comprising a pyridylaminoacetic acid compound

#77 | 2015-06-04 ✅ Patent 9,381,153 granted on 2016-07-05

US20150150794A1

Human necessities

Liquid formulations for treatment of diseases or conditions

#78 | 2015-01-08

US20150011518A1

Human necessities

NON-AQUEOUS LIQUID COMPOSITION

#79 | 2014-10-02 ✅ Patent 9,029,572 granted on 2015-05-12

US20140296540A1

Chemistry; metallurgy

3-hydroxy-6H-benzo [C] chromene-6-one derivative and manufacturing method thereof

#80 | 2014-08-28 ✅ Patent 9,062,061 granted on 2015-06-23

US20140243320A1

Chemistry; metallurgy

Compound having PARP inhibitory activity

#81 | 2014-08-07

US20140221306A1

Human necessities

OPHTHALMIC SOLUTION COMPRISING DIQUAFOSOL, METHOD FOR PRODUCING THE SAME, AND METHOD FOR INHIBITING FORMATION OF INSOLUBLE PRECIPITATE

#82 | 2014-07-10 ✅ Patent 9,387,165 granted on 2016-07-12

US20140194461A1

Human necessities

Rapamycin formulations and methods of their use

#83 | 2014-03-27

US20140088039A1

Human necessities

OPHTHALMIC SOLUTION CONTAINING HYALURONIC ACID OR SALT THEREOF AND PROPYLENE GLYCOL

#84 | 2014-01-16 ✅ Patent 9,339,496 granted on 2016-05-17

US20140018396A1

Human necessities

Composition for treating or preventing glaucoma comprising a sulfonamide compound, and a beta-receptor antagonist

#85 | 2014-01-09 ✅ Patent 8,658,667 granted on 2014-02-25

US20140011834A1

Human necessities

Stable formulations, and methods of their preparation and use

#86 | 2013-11-14 ✅ Patent 8,975,256 granted on 2015-03-10

US20130303537A1

Chemistry; metallurgy

1,2,3,4-tetrahydroquinoxaline compounds having glucocorticoid receptor binding activity

#87 | 2013-10-17

US20130275349A1

Physics

Comprehensive Glaucoma Determination Method Utilizing Glaucoma Diagnosis Chip And Deformed Proteomics Cluster Analysis

#88 | 2013-08-01 ✅ Patent 8,927,005 granted on 2015-01-06

US20130197024A1

Human necessities

Liquid formulations for treatment of diseases or conditions

#89 | 2013-07-11

US20130178524A1

Human necessities

PROSTAGLANDIN-CONTAINING PRODUCT

#90 | 2013-07-04 ✅ Patent 9,006,208 granted on 2015-04-14

US20130172287A1

Human necessities

Agent for treatment of dry eye characterized by combining P2Yreceptor agonist and hyaluronic acid or salt thereof, method for treating dry eye, and use of the P2Yreceptor agonist and hyaluronic acid or salt thereof

#91 | 2013-05-02

US20130109646A1

Human necessities

METHOD FOR TREATING GLAUCOMA OR OCULAR HYPERTENSION WITH AN ADENOSINE DERIVATIVE

#92 | 2013-04-11 ✅ Patent 8,901,155 granted on 2014-12-02

US20130090359A1

Human necessities

Method for treating a TRPV1-mediated disease

#93 | 2012-12-27 ✅ Patent 8,486,960 granted on 2013-07-16

US20120329759A1

Human necessities

Formulations and methods for vascular permeability-related diseases or conditions

#94 | 2012-12-13

US20120316158A1

Human necessities

OPHTHALMIC SOLUTION FOR TREATING OCULAR INFECTION COMPRISING LEVOFLOXACIN OR SALT THEREOF OR SOLVATE OF THE SAME, METHOD FOR TREATING OCULAR INFECTION, LEVOFLOXACIN OR SALT THEREOF OR SOLVATE OF THE SAME, AND USE THEREOF

#95 | 2012-09-13 ✅ Patent 8,536,207 granted on 2013-09-17