Hoffmann-La Roche Inc.

GLYCOSYLATED ANTIBODIES

#2 | 2025-02-06

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CELL CLASSIFICATION USING CENTER EMPHASIS OF A FEATURE MAP

#3 | 2023-07-20 ✅ Patent 12,559,561 granted on 2026-02-24

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GLYCOSYLATED ANTIBODIES

#4 | 2021-03-11 ✅ Patent 11,738,003 granted on 2023-08-29

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Method for administration

#5 | 2021-03-04 ✅ Patent 11,697,636 granted on 2023-07-11

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Substituted benzamides

#6 | 2020-07-02 ✅ Patent 11,104,668 granted on 2021-08-31

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Inhibitors of bruton's tyrosine kinase

#7 | 2020-05-28 ✅ Patent 12,023,378 granted on 2024-07-02

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Covalently linked antigen-antibody conjugates

#8 | 2020-03-19 ✅ Patent 11,382,892 granted on 2022-07-12

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Method for administration

#9 | 2020-01-23 ✅ Patent 10,767,181 granted on 2020-09-08

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Performing operations; transporting

Oligomers and oligomer conjugates

#10 | 2019-08-22 ✅ Patent 11,241,638 granted on 2022-02-08

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Chromatography column support

#11 | 2019-05-23 ✅ Patent 10,927,163 granted on 2021-02-23

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Bivalent, bispecific antibodies

#12 | 2019-04-11 ✅ Patent 10,935,298 granted on 2021-03-02

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Mechanical engineering

Cryogenic container

#13 | 2018-12-20 ✅ Patent 10,684,227 granted on 2020-06-16

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Method for detection of binding affinities

#14 | 2018-10-25 ✅ Patent 10,640,491 granted on 2020-05-05

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Inhibitors of bruton's tyrosine kinase

#15 | 2018-08-09 ✅ Patent 10,501,482 granted on 2019-12-10

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Compounds for treating spinal muscular atrophy

#16 | 2018-05-31 ✅ Patent 10,174,985 granted on 2019-01-08

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Mechanical engineering

Cryogenic container

#17 | 2018-04-12 ✅ Patent 11,491,178 granted on 2022-11-08

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Chitosan covalently linked with small molecule integrin antagonist for targeted delivery

#18 | 2017-07-27 ✅ Patent 10,877,030 granted on 2020-12-29

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Velocity factor

#19 | 2017-06-29 ✅ Patent 10,093,657 granted on 2018-10-09

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Inhibitors of bruton's tyrosine kinase

#20 | 2017-05-18 ✅ Patent 10,590,186 granted on 2020-03-17

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Immunoglobulin purification

#21 | 2017-02-09 ✅ Patent 10,227,298 granted on 2019-03-12

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Solid forms of a pharmaceutically active compound

#22 | 2017-01-19 ✅ Patent 9,951,140 granted on 2018-04-24

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Antibodies against human CSF-1R and uses thereof

#23 | 2017-01-19 ✅ Patent 10,377,794 granted on 2019-08-13

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Optimized method for antibody capturing by mixed mode chromatography

#24 | 2016-12-22 ✅ Patent 10,724,000 granted on 2020-07-28

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Small molecule based conversion of somatic cells into neural crest cells

#25 | 2016-11-17 ✅ Patent 9,580,455 granted on 2017-02-28

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Process for the recovery of beta acetylfuranoside

#26 | 2016-11-10 ✅ Patent 10,329,346 granted on 2019-06-25

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TNFa-IL-17 bispecific antibodies

#27 | 2016-11-03 ✅ Patent 9,605,006 granted on 2017-03-28

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5-aryl-1-imino-1-oxo-[1,2,4]thiadiazines

#28 | 2016-11-03 ✅ Patent 9,624,201 granted on 2017-04-18

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Inhibitors of bruton's tyrosine kinase

#29 | 2016-10-27 ✅ Patent 9,556,150 granted on 2017-01-31

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Inhibitors of bruton's tyrosine kinase

#30 | 2016-09-29 ✅ Patent 9,945,834 granted on 2018-04-17

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Method for examining a plurality of cultured cells for the presence of periodic structures of at least one target component contained in the cultured cells

#31 | 2016-09-29 ✅ Patent 9,617,260 granted on 2017-04-11

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Inhibitors of bruton's tyrosine kinase

#32 | 2016-09-22 ✅ Patent 10,053,431 granted on 2018-08-21

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Tetrahydro-benzodiazepinones

#33 | 2016-09-15 ✅ Patent 10,501,411 granted on 2019-12-10

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Substituted benzamides

#34 | 2016-08-18 ✅ Patent 9,447,086 granted on 2016-09-20

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6-amino acid heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis B virus infection

#35 | 2016-08-11 ✅ Patent 9,670,211 granted on 2017-06-06

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Aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection

#36 | 2016-08-04

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Performing operations; transporting

COMBINATION THERAPY OF ANTIBODIES AGAINST HUMAN CSF-1R AND TLR9 AGONIST

#37 | 2016-07-28 ✅ Patent 10,052,567 granted on 2018-08-21

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Moveable chromatography column separator

#38 | 2016-07-21 ✅ Patent 10,023,589 granted on 2018-07-17

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Pyrazolo[1,5a]pyrimidine derivatives as IRAK4 modulators

#39 | 2016-07-07 ✅ Patent 9,932,335 granted on 2018-04-03

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Pyrrolopyridine or pyrazolopyridine derivatives

#40 | 2016-06-16

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THERAPEUTIC FUSION PROTEIN

#41 | 2016-03-03 ✅ Patent 9,809,599 granted on 2017-11-07

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Aryl-quinoline derivatives

#42 | 2016-02-25 ✅ Patent 9,624,302 granted on 2017-04-18

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Nucleic acids encoding antibodies against human CSF-1R

#43 | 2016-02-25 ✅ Patent 11,447,478 granted on 2022-09-20

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BACE1 inhibitors

#44 | 2016-02-25 ✅ Patent 9,486,445 granted on 2016-11-08

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Combination therapy for proliferative disorders

#45 | 2016-01-28 ✅ Patent 9,409,888 granted on 2016-08-09

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Dimeric compounds

#46 | 2016-01-21 ✅ Patent 10,308,659 granted on 2019-06-04

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Pyridine derivatives

#47 | 2016-01-07 ✅ Patent 9,469,644 granted on 2016-10-18

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Inhibitors of Bruton's tyrosine kinase

#48 | 2016-01-07 ✅ Patent 9,828,340 granted on 2017-11-28

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Asymmetric synthesis of a substituted pyrrolidine-2-carboxamide

#49 | 2016-01-07 ✅ Patent 9,382,218 granted on 2016-07-05

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N-heteroaryl substituted aniline derivatives as HCV-antivirals

#50 | 2016-01-07 ✅ Patent 9,693,997 granted on 2017-07-04

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Antiviral compounds

#51 | 2015-12-31 ✅ Patent 10,155,970 granted on 2018-12-18

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Use of an amino acid auxotrophy cured prokaryotic strain for the recombinant production of a polypeptide

#52 | 2015-12-31 ✅ Patent 9,663,494 granted on 2017-05-30

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Inhibitors of bruton's tyrosine kinase

#53 | 2015-12-31 ✅ Patent 9,896,433 granted on 2018-02-20

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Antiviral compounds

#54 | 2015-12-24 ✅ Patent 9,540,345 granted on 2017-01-10

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Antiviral compounds

#55 | 2015-12-10

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ANTIBODY FORMULATION

#56 | 2015-12-10 ✅ Patent 9,359,345 granted on 2016-06-07

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Thiazole derivatives as inhibitors of Bruton's tyrosine kinase

#57 | 2015-12-10 ✅ Patent 9,511,059 granted on 2016-12-06

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Antiviral compounds

#58 | 2015-12-10 ✅ Patent 9,611,224 granted on 2017-04-04

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Antiproliferative benzo [B] azepin-2-ones

#59 | 2015-11-26 ✅ Patent 9,405,069 granted on 2016-08-02

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Method for preparing an outer surface of a planar waveguide to be capable of binding target samples along a plurality of predeterminded lines and a planar waveguide

#60 | 2015-11-19 ✅ Patent 9,464,098 granted on 2016-10-11

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Substituted triazole boronic acid compounds

#61 | 2015-11-12 ✅ Patent 9,766,251 granted on 2017-09-19

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Anti-human IgG1 antibody

#62 | 2015-11-05 ✅ Patent 9,290,465 granted on 2016-03-22

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Substituted isoxazole amine compounds as inhibitors of SCD1

#63 | 2015-10-29

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ANTIVIRAL COMPOUNDS

#64 | 2015-10-29

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CHITOSAN COVALENTLY LINKED WITH SMALL MOLECULE INTEGRIN ANTAGONIST FOR TARGETED DELIVERY

#65 | 2015-10-15 ✅ Patent 9,458,105 granted on 2016-10-04

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Inhibitors of Bruton's tyrosine kinase

#66 | 2015-10-08 ✅ Patent 10,112,928 granted on 2018-10-30

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Inhibitors of SYK

#67 | 2015-10-01 ✅ Patent 10,156,524 granted on 2018-12-18

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Device for use in the detection of binding affinities

#68 | 2015-10-01 ✅ Patent 9,499,626 granted on 2016-11-22

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Antibodies against human CSF-1R and uses thereof

#69 | 2015-10-01 ✅ Patent 9,499,625 granted on 2016-11-22

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Antibodies against human CSF-1R and uses thereof

#70 | 2015-10-01 ✅ Patent 9,403,805 granted on 2016-08-02

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Antiviral compounds

#71 | 2015-09-24 ✅ Patent 9,309,248 granted on 2016-04-12

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Azaindolines

#72 | 2015-09-10 ✅ Patent 9,340,573 granted on 2016-05-17

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Azaindolines

#73 | 2015-09-03 ✅ Patent 9,403,768 granted on 2016-08-02

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Indolines

#74 | 2015-08-27 ✅ Patent 9,303,076 granted on 2016-04-05

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Cell-penetrating peptides and uses thereof

#75 | 2015-08-13 ✅ Patent 9,422,331 granted on 2016-08-23

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2-oxo-2,3,4,5-tetrahydro-1 H-benzo[B]diazepines and their use in the treatment of cancer

#76 | 2015-08-06 ✅ Patent 9,334,278 granted on 2016-05-10

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Pyrrolo[2,3-B]pyrazines as SYK inhibitors

#77 | 2015-08-06 ✅ Patent 9,169,215 granted on 2015-10-27

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LPAR—substituted cyanopyrazole compounds

#78 | 2015-07-30 ✅ Patent 9,422,332 granted on 2016-08-23

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Azaheterocycles as BIR2 and/or BIR3 inhibitors

#79 | 2015-07-30 ✅ Patent 9,499,548 granted on 2016-11-22

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Inhibitors of bruton's tyrosine kinase

#80 | 2015-07-23 ✅ Patent 9,266,861 granted on 2016-02-23

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Method of synthesizing thyroid hormone analogs and polymorphs thereof

#81 | 2015-07-16 ✅ Patent 9,334,480 granted on 2016-05-10

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Compounds for improved stem cell differentiation into hepatocytes

#82 | 2015-06-25 ✅ Patent 9,617,342 granted on 2017-04-11

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Nucleic acids encoding antibodies against human CSF-1R and uses thereof

#83 | 2015-06-18 ✅ Patent 9,409,961 granted on 2016-08-09

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Cell penetrating peptides to target EIF4E

#84 | 2015-06-18 ✅ Patent 9,133,170 granted on 2015-09-15

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Inhibitors of HCV NS5A

#85 | 2015-06-11 ✅ Patent 9,499,624 granted on 2016-11-22

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Antibodies against human CSF-1R and uses thereof

#86 | 2015-06-11 ✅ Patent 9,181,218 granted on 2015-11-10

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Compounds for improved stem cell differentiation into hepatocytes

#87 | 2015-06-11 ✅ Patent 9,956,243 granted on 2018-05-01

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Combination treatment for acute myeloid leukemia (AML)

#88 | 2015-06-04 ✅ Patent 10,385,022 granted on 2019-08-20

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3-amino-pyridines as GPBAR1 agonists

#89 | 2015-05-21 ✅ Patent 9,273,042 granted on 2016-03-01

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5-amino[1,4]thiazines as BACE 1 inhibitors

#90 | 2015-05-14 ✅ Patent 9,181,232 granted on 2015-11-10

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Difluoro-hexahydro-cyclopentaoxazinyls and difluoro-hexahydro-benzooxazinyls as BACE1 inhibitors

#91 | 2015-05-14 ✅ Patent 9,714,292 granted on 2017-07-25

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Bispecific antibodies against human TWEAK and human IL17 and uses thereof

#92 | 2015-04-30 ✅ Patent 9,212,171 granted on 2015-12-15

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Ethynyl compounds

#93 | 2015-03-19

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ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOF

#94 | 2015-03-12 ✅ Patent 9,671,394 granted on 2017-06-06

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Method for the detection of free binding partner of a multispecific binder

#95 | 2015-03-05 ✅ Patent 9,650,363 granted on 2017-05-16

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Integrin antagonist conjugates for targeted delivery to cells expressing LFA-1

#96 | 2015-02-26

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COMBINATION THERAPY OF A TYPE II ANTI-CD20 ANTIBODY WITH AN ANTI-BCL-2 ACTIVE AGENT

#97 | 2015-02-12

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BISPECIFIC, TETRAVALENT ANTIGEN BINDING PROTEINS

#98 | 2015-02-05 ✅ Patent 9,586,916 granted on 2017-03-07

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Integrin antagonist conjugates for targeted delivery to cells expressing alpha-V-beta-3

#99 | 2015-02-05

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FULL LENGTH ANTIBODY DISPLAY SYSTEM FOR EUKARYOTIC CELLS AND ITS USE

#100 | 2015-01-29 ✅ Patent 9,447,035 granted on 2016-09-20

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