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Assignee profile:

Parion Sciences, Inc.

City:

Durham, North Carolina

Country:

United States

Published Applications:

110

Last publication date:

2025-04-10

Patent Grants:

Last grant date:

2023-02-14

Top Inventors for applications by Parion Sciences, Inc.

These are the the leading inventors for applications assigned to Parion Sciences, Inc.:

MICHAEL R. JOHNSON 68 Chapel Hill, NC United States
Michael Ross Johnson 27 Chapel Hill, NC United States
Richard C. Boucher 17 Chapel Hill, NC United States
Jianzhong Zhang 15 Rensselaer, NY United States

Michael R. Johnson 14 Durham, NC United States
Bruce Sargent 14 Delmar, NY United States
Bruce F. MOLINO 13 Slingerlands, NY United States
William Robert THELIN 9 Chapel Hill, NC United States

Bruce Molino 8 Slingerlands, NY United States
William R. Thelin 8 Chapel Hill, NC United States
Tomas NAVRATIL 6 Carrboro, NC United States
Andrew J. Hirsh 5 Durham, NC United States

Mark Jeffrey Edhouse 4 Cambridge, United Kingdom
Anthony J. Hickey 4 Chapel Hill, NC United States
Brian M. Button 4 Hillsborough, NC United States
Donal Joseph TAYLOR 4 Cambridge, United Kingdom

James B. Fink 4 San Mateo, CA United States
Paul Boucher 4 Cary, NC United States
Stuart Robert ABERCROMBIE 4 Cambridge, United Kingdom
Samuel E. HOPKINS 3 Raleigh, NC United States

Richard Boucher 3 Chapel Hill, NC United States
Nicholas O. Heijne 3 Cambridge, United Kingdom
Philip Jerome Driver 3 Cambridge, United Kingdom
Ronald A. Aungst, JR. 2 Clifton Park, NY United States

Marino Convertino 2 Durham, NC United States
Brian Button 2 Hillsborough, NC United States
Jonathan Hugh Wilkins 2 Chichester, United Kingdom
Matthew Voss 2 Durham, NC United States

Michael R. Johnson 1 , United States
Parion Sciences, Inc. 1 , United States
Jonathan Hugh WILKINS 1 Cambridge, United Kingdom
Stuart Robert Abercrombie 1 Cambrige, United Kingdom

Diane VILLALON 1 Cary, NC United States
Donial Joseph Taylor 1 Cambridge, United Kingdom
Keith A. Johnson 1 Durham, NC United States
Jone L. BOYER 1 Chapel Hill, NC United States

Jonathan Hugh WILKINS 1 West Sussex, United Kingdom
Guy Conwyn Julian MOSELEY 1 Cambridge, United Kingdom
Emma Jane HASLER 1 Suffolk, United Kingdom
Jose L. BOYER 1 Chapel Hill, NC United States

Jamie Alan GREENWOOD 1 Royston, United Kingdom
Michael Richard BURCHER 1 Cambridge, United Kingdom
William R. Thelin 1 Durham, NC United States
Richard BOUCHER 1 Cary, NC United States

Richard C. BOUCHER 1 Durham, NC United States
Michael JOHNSON 1 Chapel Hill, NC United States
David William SMITH 1 Cambridge, United Kingdom

Recent patent applications by Parion Sciences, Inc.

Parion Sciences, Inc. based in Durham, US has been assigned the rights to these inventions. The list includes both Pending Applications and Patent Grants:

#1 | 2025-04-10

US20250115561A1

Chemistry; metallurgy

BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS

#2 | 2025-04-03

US20250109110A1

Chemistry; metallurgy

BICYCLIC-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS

#3 | 2021-01-28 ✅ Patent 11,578,042 granted on 2023-02-14

US20210024471A1

Chemistry; metallurgy

3,5-diamino-6-chloro-N-(N-(4-(4-(2-(hexyl(2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)carbamimidoyl)pyrazine-2-carboxamide

#4 | 2020-02-20

US20200054558A1

Human necessities

AEROSOL DELIVERY SYSTEMS, COMPOSITIONS AND METHODS

#5 | 2019-10-10

US20190308943A1

Chemistry; metallurgy

3,5-DIAMINO-6-CHLORO-N-(N-(4-PHENYLBUTYL)CARBAMIMIDOYL) PYRAZINE-2- CARBOXAMIDE COMPOUNDS

#6 | 2019-08-08

US20190241528A1

Chemistry; metallurgy

SODIUM CHANNEL BLOCKERS

#7 | 2019-03-21

US20190084943A1

Chemistry; metallurgy

CHLORO-PYRAZINE CARBOXAMIDE DERIVATIVES WITH EPITHELIAL SODIUM CHANNEL BLOCKING ACTIVITY

#8 | 2019-01-31 ✅ Patent 10,968,233 granted on 2021-04-06

US20190031679A1

Chemistry; metallurgy

Monothiol mucolytic agents

#9 | 2019-01-10 ✅ Patent 10,233,158 granted on 2019-03-19

US20190010132A1

Chemistry; metallurgy

Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds

#10 | 2018-04-26 ✅ Patent 10,526,292 granted on 2020-01-07

US20180111907A1

Chemistry; metallurgy

Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry eye and other mucosal diseases

#11 | 2018-04-19 ✅ Patent 10,159,672 granted on 2018-12-25

US20180104241A1

Human necessities

Chemically and metabolically stable dipeptide possessing potent sodium channel blocker activity

#12 | 2018-04-05

US20180092915A1

Human necessities

SODIUM CHANNEL BLOCKERS FOR SKIN DISORDERS

#13 | 2017-12-21 ✅ Patent 10,246,425 granted on 2019-04-02

US20170362187A1

Chemistry; metallurgy

3,5-diamino-6-chloro-N-(N-(4-phenylbutyl)carbamimidoyl) pyrazine-2-carboxamide compounds

#14 | 2017-11-23 ✅ Patent 10,752,597 granted on 2020-08-25

US20170334864A1

Chemistry; metallurgy

3,5-diamino-6-chloro-N—(N-(4-(4-(2-(hexyl(2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)carbamimidoyl)pyrazine-2-carboxamide

#15 | 2017-11-16 ✅ Patent 10,071,970 granted on 2018-09-11

US20170327472A1

Chemistry; metallurgy

Chloro-pyrazine carboxamide derivatives with epithelial sodium channel blocking activity

#16 | 2017-10-26 ✅ Patent 9,957,238 granted on 2018-05-01

US20170305868A1

Chemistry; metallurgy

Arylalkyl-and aryloxyalkyl-substituted epithelial sodium channel blocking compounds

#17 | 2017-10-05

US20170281620A1

Human necessities

CHEMICALLY AND METABOLICALLY STABLE DIPEPTIDE POSSESSING POTENT SODIUM CHANNEL BLOCKER ACTIVITY

#18 | 2017-09-21 ✅ Patent 10,167,266 granted on 2019-01-01

US20170267650A1

Chemistry; metallurgy

Sodium channel blockers

#19 | 2017-09-21 ✅ Patent 9,856,224 granted on 2018-01-02

US20170267649A1

Chemistry; metallurgy

Stable sodium channel blockers

#20 | 2017-06-01 ✅ Patent 9,987,443 granted on 2018-06-05

US20170151396A1

Human necessities

Inhaled hypertonic saline delivered by a heated nasal cannula

#21 | 2017-01-26 ✅ Patent 9,849,129 granted on 2017-12-26

US20170020870A1

Human necessities

Sodium channel blockers for skin disorders

#22 | 2016-11-03 ✅ Patent 10,526,283 granted on 2020-01-07

US20160318861A1

Chemistry; metallurgy

Prodrugs of dithiol mucolytic agents

#23 | 2016-08-04 ✅ Patent 10,106,551 granted on 2018-10-23

US20160222023A1

Chemistry; metallurgy

Monothiol mucolytic agents

#24 | 2016-07-07 ✅ Patent 9,963,427 granted on 2018-05-08

US20160194278A1

Chemistry; metallurgy

Dithiol mucolytic agents

#25 | 2016-05-05 ✅ Patent 9,878,988 granted on 2018-01-30

US20160122306A1

Chemistry; metallurgy

Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry eye and other mucosal diseases

#26 | 2015-12-31

US20150376146A1

Chemistry; metallurgy

SODIUM CHANNEL BLOCKERS

#27 | 2015-12-31

US20150376145A1

Chemistry; metallurgy

STABLE SODIUM CHANNEL BLOCKERS

#28 | 2015-10-29

US20150307530A1

Chemistry; metallurgy

NOVEL MUCOLYTIC AGENTS

#29 | 2015-10-22 ✅ Patent 9,695,134 granted on 2017-07-04

US20150299142A1

Chemistry; metallurgy

3,5-diamino-6-chloro-N-(n-(4-phenylbutyl)carbamimidoyl)pyrazine-2-carboxamide compounds

#30 | 2015-10-15 ✅ Patent 9,655,896 granted on 2017-05-23

US20150290189A1

Human necessities

Chemically and metabolically stable dipeptide possessing potent sodium channel blocker activity

#31 | 2015-06-18 ✅ Patent 9,586,911 granted on 2017-03-07

US20150166488A1

Chemistry; metallurgy

Arylalkyl- and aryloxyalkyl-substituted epthelial sodium channel blocking compounds

#32 | 2015-06-18 ✅ Patent 9,102,633 granted on 2015-08-11

US20150166487A1

Chemistry; metallurgy

Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds

#33 | 2015-06-04

US20150150803A1

Human necessities

AEROSOL DELIVERY SYSTEMS, COMPOSITIONS AND METHODS

#34 | 2015-04-16 ✅ Patent 10,335,558 granted on 2019-07-02

US20150101597A1

Human necessities

Methods of treatment

#35 | 2015-04-09 ✅ Patent 9,260,398 granted on 2016-02-16

US20150099764A1

Chemistry; metallurgy

Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry eye and other mucosal diseases

#36 | 2015-02-26 ✅ Patent 9,346,753 granted on 2016-05-24

US20150056305A1

Chemistry; metallurgy

Dithiol mucolytic agents

#37 | 2014-06-26

US20140179625A1

Chemistry; metallurgy

SODIUM CHANNEL BLOCKERS

#38 | 2014-06-19 ✅ Patent 9,593,084 granted on 2017-03-14

US20140171447A1

Chemistry; metallurgy

Chloro-pyrazine carboxamide derivatives with epithelial sodium channel blocking activity

#39 | 2014-06-19 ✅ Patent 9,029,382 granted on 2015-05-12

US20140170244A1

Chemistry; metallurgy

3,5-diamino-6-chloro-N-(N-(4-phenylbutyl)carbamimidoyl) pyrazine-2-carboxamide compounds

#40 | 2014-06-12

US20140158127A1

Human necessities

NASAL CANNULA FOR DELIVERY OF AEROSOLIZED MEDICAMENTS

#41 | 2014-05-22 ✅ Patent 9,072,738 granted on 2015-07-07

US20140142118A1

Human necessities

Chemically and metabolically stable dipeptide possessing potent sodium channel blocker activity

#42 | 2014-04-24 ✅ Patent 8,945,605 granted on 2015-02-03

US20140109899A1

Human necessities

Aerosol delivery systems, compositions and methods

#43 | 2014-04-17 ✅ Patent 9,586,910 granted on 2017-03-07

US20140107133A1

Chemistry; metallurgy

3,5-diamino-6-chloro-N-(N-(4-(4-(2-(hexyl(2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)carbamimidoyl)pyrazine-2-carboxamide

#44 | 2014-04-10 ✅ Patent 9,408,988 granted on 2016-08-09

US20140096765A1

Human necessities

Inhaled hypertonic saline delivered by a heated nasal cannula

#45 | 2014-01-30

US20140031371A1

Chemistry; metallurgy

POLY AROMATIC SODIUM CHANNEL BLOCKERS

#46 | 2013-12-05 ✅ Patent 8,980,898 granted on 2015-03-17

US20130324559A1

Human necessities

Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry eye and other mucosal diseases

#47 | 2013-07-11 ✅ Patent 8,669,262 granted on 2014-03-11

US20130178482A1

Human necessities

3,5-diamino-6-chloro-N-(N-(4-(4-(2-(hexyl(2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)carbamimidoyl)pyrazine-2-carboxamide

#48 | 2013-03-28 ✅ Patent 8,778,383 granted on 2014-07-15

US20130074842A1

Human necessities

Methods of treatment

#49 | 2013-01-10 ✅ Patent 8,846,688 granted on 2014-09-30

US20130012692A1

Human necessities

Sodium channel blockers

#50 | 2012-08-30 ✅ Patent 8,507,497 granted on 2013-08-13

US20120220606A1

Chemistry; metallurgy

Capped pyrazinoylguanidine sodium channel blockers

#51 | 2012-06-28

US20120165342A1

Chemistry; metallurgy

Methods of Reducing Risk of Infection from Pathogens

#52 | 2012-05-10 ✅ Patent 8,575,176 granted on 2013-11-05

US20120116083A1

Chemistry; metallurgy

Heteroaromatic pyrazinoylguanidine sodium channel blockers

#53 | 2011-08-11

US20110195973A1

Chemistry; metallurgy

CYCLIC SUBSTITUTED PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS POSSESSING BETA AGONIST ACTIVITY

#54 | 2011-06-16 ✅ Patent 8,314,105 granted on 2012-11-20

US20110144338A1

Chemistry; metallurgy

Methods of reducing risk of infection from pathogens

#55 | 2011-02-24 ✅ Patent 8,431,579 granted on 2013-04-30

US20110046158A1

Chemistry; metallurgy

Capped pyrazinoylguanidine sodium channel blockers

#56 | 2011-01-13 ✅ Patent 8,163,758 granted on 2012-04-24

US20110008268A1

Chemistry; metallurgy

Phenyl substituted pyrazinoylguanidine sodium channel blockers possessing beta agonist activity

#57 | 2011-01-06 ✅ Patent 8,211,895 granted on 2012-07-03

US20110003832A1

Chemistry; metallurgy

Capped pyrazinoylguanidine sodium channel blockers

#58 | 2010-10-21 ✅ Patent 8,324,218 granted on 2012-12-04

US20100267746A1

Chemistry; metallurgy

Aliphatic pyrazinoylguanidine sodium channel blockers with beta agonist activity

#59 | 2010-06-10 ✅ Patent 8,227,474 granted on 2012-07-24

US20100144661A1

Human necessities

Sodium channel blockers

#60 | 2010-03-25

US20100074881A1

Human necessities

MULTIPLE NEBULIZER SYSTEMS

#61 | 2009-12-31

US20090324724A1

Chemistry; metallurgy

SOLUBLE AMIDE & ESTER PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS

#62 | 2009-09-10 ✅ Patent 7,956,059 granted on 2011-06-07

US20090227594A1

Chemistry; metallurgy

Aliphatic amide and ester pyrazinoylguanidine sodium channel blockers

#63 | 2009-09-10 ✅ Patent 8,198,286 granted on 2012-06-12

US20090227530A1

Human necessities

Sodium channel blockers

#64 | 2009-08-27 ✅ Patent 8,124,607 granted on 2012-02-28

US20090214444A1

Chemistry; metallurgy

Poly aromatic pyrazinoylguanidine sodium channel blockers

#65 | 2009-04-23 ✅ Patent 8,551,534 granted on 2013-10-08

US20090104272A1

Human necessities

Inhaled hypertonic saline delivered by a heated nasal cannula

#66 | 2009-03-26 ✅ Patent 7,981,898 granted on 2011-07-19

US20090082287A1

Human necessities

Methods of enhancing mucosal hydration and mucosal clearance by treatment with sodium channel blockers and osmolytes

#67 | 2009-03-19 ✅ Patent 7,842,697 granted on 2010-11-30

US20090076273A1

Chemistry; metallurgy

Soluble amide and ester pyrazinoylguanidine sodium channel blockers

#68 | 2009-03-05

US20090062308A1

Human necessities

METHODS OF USING SODIUM CHANNEL BLOCKERS

#69 | 2009-01-15

US20090018144A1

Chemistry; metallurgy

CAPPED PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS

#70 | 2008-11-27

US20080293740A1

Human necessities

METHOD OF TREATING ACID-SENSING ION CHANNEL MEDIATED PAIN, COUGH SUPPRESSION, AND CENTRAL NERVOUS SYSTEM DISORDERS

#71 | 2008-10-09 ✅ Patent 8,288,391 granted on 2012-10-16

US20080249109A1

Human necessities

Pyrazinoylguanidine compounds for use as taste modulators

#72 | 2008-08-21

US20080200476A1

Chemistry; metallurgy

ALAPHATIC PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS

#73 | 2008-07-24 ✅ Patent 8,022,210 granted on 2011-09-20

US20080177072A1

Chemistry; metallurgy

Soluble amide and ester pyrazinoylguanidine sodium channel blockers

#74 | 2008-07-24

US20080176863A1

Chemistry; metallurgy

CAPPED PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS

#75 | 2008-07-17 ✅ Patent 7,868,010 granted on 2011-01-11

US20080171880A1

Chemistry; metallurgy

Capped pyrazinoylguanidine sodium channel blockers

#76 | 2008-07-17 ✅ Patent 8,008,494 granted on 2011-08-30

US20080171879A1

Chemistry; metallurgy

Soluble amide and ester pyrazinoylguanidine sodium channel blockers

#77 | 2008-07-10

US20080167466A1

Chemistry; metallurgy

CAPPED PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS

#78 | 2008-05-06 ✅ Patent 7,368,450 granted on 2008-05-06

US10828354

Sodium channel blockers

#79 | 2008-05-01

US20080103148A1

Chemistry; metallurgy

CYCLIC PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS

#80 | 2008-04-24 ✅ Patent 8,143,256 granted on 2012-03-27

US20080096896A1

Chemistry; metallurgy

Cyclic amide and ester pyrazinoylguanidine sodium channel blockers

#81 | 2008-04-17 ✅ Patent 8,058,278 granted on 2011-11-15

US20080090841A1

Human necessities

Methods of enhancing mucosal hydration and mucosal clearance by treatment with sodium channel blockers and osmolytes

#82 | 2008-03-27 ✅ Patent 7,820,678 granted on 2010-10-26

US20080076782A1

Human necessities

Sodium channel blockers

#83 | 2008-02-19 ✅ Patent 7,332,496 granted on 2008-02-19

US10828479

Methods of using sodium channel blockers

#84 | 2007-11-15

US20070265280A1

Human necessities

METHODS OF USING SODIUM CHANNEL BLOCKERS

#85 | 2007-07-24 ✅ Patent 7,247,636 granted on 2007-07-24

US10828235

Phenolic guanidine sodium channel blockers

#86 | 2007-07-10 ✅ Patent 7,241,766 granted on 2007-07-10

US10828278

Methods of using phenolic guanidine sodium channel blockers

#87 | 2007-03-20 ✅ Patent 7,192,960 granted on 2007-03-20

US10828466

Sodium channel blockers

#88 | 2007-03-20 ✅ Patent 7,192,959 granted on 2007-03-20

US10828353

Sodium channel blockers

#89 | 2007-03-20 ✅ Patent 7,192,958 granted on 2007-03-20

US10828329

Sodium channel blockers

#90 | 2007-03-13 ✅ Patent 7,189,719 granted on 2007-03-13

US10828171

Sodium channel blockers

#91 | 2007-03-06 ✅ Patent 7,186,833 granted on 2007-03-06

US10828352

Sodium channel blockers

#92 | 2007-02-08 ✅ Patent 7,807,834 granted on 2010-10-05

US20070032509A1

Chemistry; metallurgy

Capped pyrazinoylguanidine sodium channel blockers

#93 | 2006-09-14 ✅ Patent 7,410,968 granted on 2008-08-12

US20060205738A1

Chemistry; metallurgy

Capped pyrazinoylguanidine sodium channel blockers

#94 | 2006-06-29 ✅ Patent 7,875,619 granted on 2011-01-25

US20060142581A1

Human necessities

Hetero substituted sodium channel blockers

#95 | 2006-03-23 ✅ Patent 7,345,044 granted on 2008-03-18

US20060063780A1

Human necessities

Sodium channel blockers

#96 | 2006-03-09 ✅ Patent 7,368,451 granted on 2008-05-06

US20060052395A1

Chemistry; metallurgy

Capped pyrazinoylguanidine sodium channel blockers

#97 | 2006-03-09 ✅ Patent 7,368,447 granted on 2008-05-06

US20060052394A1

Chemistry; metallurgy

Capped pyrazinoylguanidine sodium channel blockers

#98 | 2006-02-23 ✅ Patent 7,399,766 granted on 2008-07-15

US20060040954A1

Chemistry; metallurgy

Soluble amide & ester pyrazinoylguanidine sodium channel blockers

#99 | 2005-10-20 ✅ Patent 7,247,637 granted on 2007-07-24

US20050234072A1

Chemistry; metallurgy

Capped pyrazinoylguanidine sodium channel blockers

#100 | 2005-10-13 ✅ Patent 7,388,013 granted on 2008-06-17

US20050228182A1

Chemistry; metallurgy

Capped pyrazinoylguanidine sodium channel blockers

Also check out Parion Sciences, Inc.'s (Durham, United States) applicant profile with 32 patent applications submitted.

AssigneeID:

3751 ⎘