Ablynx N.V. based in Zwijnaarde, BE has been assigned the rights to these inventions. The list includes both Pending Applications and Patent Grants:

#1 | 2026-05-21

US20260139042A1

Chemistry; metallurgy

IMMUNOGLOBULIN VARIABLE DOMAINS

#2 | 2026-05-21

US20260139040A2

Chemistry; metallurgy

PRECISION ACTIVATED POLYPEPTIDES

#3 | 2026-02-12

US20260042798A1

Chemistry; metallurgy

CHROMATOGRAPHY-FREE ANTIBODY PURIFICATION METHOD

#4 | 2025-07-24

US20250236673A1

Chemistry; metallurgy

PROTEIN-BASED CARRIERS FOR SITE-SPECIFIC AMINE CONJUGATION

#5 | 2025-04-24

US20250129183A1

Chemistry; metallurgy

MMP13 BINDING IMMUNOGLOBULINS

#6 | 2025-04-17

US20250122547A1

Chemistry; metallurgy

METHOD FOR THE PRODUCTION OF DOMAIN ANTIBODIES

#7 | 2024-12-19

US20240415974A1

Human necessities

PROTEIN-BASED CONJUGATION CARRIERS

#8 | 2024-11-07

US20240368250A1

Chemistry; metallurgy

POLYPEPTIDES BINDING TO THE NEONATAL FC RECEPTOR

#9 | 2024-10-17

US20240343823A1

Chemistry; metallurgy

POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS TARGETING GLYPICAN-3 AND T CELL RECEPTOR

#10 | 2024-09-12

US20240301049A1

Chemistry; metallurgy

POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS TARGETING IL-6 AND TNF ALPHA

#11 | 2024-09-05

US20240294617A1

Chemistry; metallurgy

SERUM ALBUMIN BINDERS

#12 | 2024-08-22 ✅ Patent 12,221,487 granted on 2025-02-11

US20240279349A2

Chemistry; metallurgy

CX3CR1-BINDING POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS

#13 | 2024-06-20

US20240199740A1

Chemistry; metallurgy

T CELL RECRUITING POLYPEPTIDES CAPABLE OF BINDING CD123 AND TCR ALPHA/BETA

#14 | 2024-06-06

US20240182575A1

Chemistry; metallurgy

AMINO ACID SEQUENCES THAT MODULATE THE INTERACTION BETWEEN CELLS OF THE IMMUNE SYSTEM

#15 | 2024-06-06

US20240181006A1

Human necessities

POLYPEPTIDES BINDING ADAMTS5, MMP13 AND AGGRECAN

#16 | 2024-04-11

US20240117038A1

Chemistry; metallurgy

CX3CR1-BINDING COMPOUNDS, METHODS AND USES THEREOF

#17 | 2024-04-04

US20240109965A1

Chemistry; metallurgy

IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS TARGETING T CELL RECEPTOR

#18 | 2024-01-25

US20240026013A2

Chemistry; metallurgy

CX3CR1-BINDING POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS

#19 | 2023-10-05

US20230312694A1

Chemistry; metallurgy

AGGRECAN BINDING IMMUNOGLOBULINS

#20 | 2023-08-03

US20230242620A1

Chemistry; metallurgy

TECHNIQUES FOR PREDICTING, DETECTING AND REDUCING ASPECIFIC PROTEIN INTERFERENCE IN ASSAYS INVOLVING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS

#21 | 2023-07-06 ✅ Patent 12,384,835 granted on 2025-08-12

US20230211006A1

Human necessities

CYSTEINE LINKED NANOBODY DIMERS

#22 | 2023-05-04

US20230136595A1

Chemistry; metallurgy

METHOD FOR THE PRODUCTION AND PURIFICATION OF MULTIVALENT IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS

#23 | 2023-03-02 ✅ Patent 12,630,617 granted on 2026-05-19

US20230060574A1

Chemistry; metallurgy

SERUM ALBUMIN BINDERS

#24 | 2023-02-16 ✅ Patent 12,662,527 granted on 2026-06-23

US20230050615A1

Chemistry; metallurgy

IMPROVED SERUM ALBUMIN BINDING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS

#25 | 2023-02-16 ✅ Patent 12,221,487 granted on 2025-02-11

US20230046772A1

Chemistry; metallurgy

Nucleic acids encoding CX3CR1-binding polypeptides comprising immunoglobulin single variable domains

#26 | 2023-02-02

US20230031229A1

Chemistry; metallurgy

NANOBODIES AGAINST TUMOR NECROSIS FACTOR-ALPHA

#27 | 2022-12-29 ✅ Patent 11,919,966 granted on 2024-03-05

US20220411521A1

Chemistry; metallurgy

Methods for inhibiting tumor growth or treating cancer by administering an immunoglobulin single variable domain that binds glucocorticoid-induced TNFR family-related receptor (GITR)

#28 | 2022-11-24

US20220372128A1

Chemistry; metallurgy

POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS TARGETING TNFA AND IL-23

#29 | 2022-11-17 ✅ Patent 12,528,860 granted on 2026-01-20

US20220363747A1

Chemistry; metallurgy

POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS TARGETING TNFA AND IL-23

#30 | 2022-11-17 ✅ Patent 12,285,493 granted on 2025-04-29

US20220362393A1

Human necessities

Polypeptides antagonizing Wnt signaling in tumor cells

#31 | 2022-11-10 ✅ Patent 11,897,951 granted on 2024-02-13

US20220356241A1

Chemistry; metallurgy

Polypeptides comprising immunoglobulin single variable domains targeting IL-6 and TNF-α

#32 | 2022-10-20

US20220332807A1

Chemistry; metallurgy

IMMUNOGLOBULIN VARIABLE DOMAINS

#33 | 2022-10-20

US20220332806A1

Chemistry; metallurgy

IMMUNOGLOBULIN VARIABLE DOMAINS

#34 | 2022-10-13

US20220324951A1

Chemistry; metallurgy

GLYCOSYLATED IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS

#35 | 2022-09-22 ✅ Patent 12,662,525 granted on 2026-06-23

US20220298227A9

Chemistry; metallurgy

TECHNIQUES FOR PREDICTING, DETECTING AND REDUCING ASPECIFIC PROTEIN INTERFERENCE IN ASSAYS INVOLVING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS

#36 | 2022-08-11 ✅ Patent 11,708,404 granted on 2023-07-25

US20220251183A1

Chemistry; metallurgy

Immunoglobulin variable domains

#37 | 2022-08-04

US20220242958A1

Chemistry; metallurgy

BISPECIFIC NANOBODIES

#38 | 2022-07-07 ✅ Patent 11,932,702 granted on 2024-03-19

US20220213215A1

Chemistry; metallurgy

Polypeptides comprising immunoglobulin single variable domains targeting glypican-3 and T cell receptor

#39 | 2022-06-09 ✅ Patent 12,492,248 granted on 2025-12-09

US20220177566A1

Chemistry; metallurgy

POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS TARGETING IL-13 AND TSLP

#40 | 2022-06-09 ✅ Patent 11,840,566 granted on 2023-12-12

US20220177565A1

Chemistry; metallurgy

Methods of treating asthma with polypeptides targeting IL-13 and TSLP

#41 | 2022-06-09 ✅ Patent 12,384,840 granted on 2025-08-12

US20220177564A1

Chemistry; metallurgy

POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS TARGETING IL-13 AND TSLP

#42 | 2022-06-09

US20220175923A1

Human necessities

FORMULATIONS OF SINGLE DOMAIN ANTIGEN BINDING MOLECULES

#43 | 2022-05-19 ✅ Patent 12,509,522 granted on 2025-12-30

US20220153854A1

Chemistry; metallurgy

POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS TARGETING IL-13 AND OX40L

#44 | 2022-05-05 ✅ Patent 11,312,765 granted on 2022-04-26

US20220135657A9

Chemistry; metallurgy

Immunoglobulin variable domains

#45 | 2022-04-21 ✅ Patent 11,485,778 granted on 2022-11-01

US20220119512A1

Chemistry; metallurgy

Immunoglobulin variable domains

#46 | 2022-04-21 ✅ Patent 12,516,105 granted on 2026-01-06

US20220119497A1

Chemistry; metallurgy

TECHNIQUES FOR PREDICTING, DETECTING AND REDUCING ASPECIFIC PROTEIN INTERFERENCE IN ASSAYS INVOLVING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS

#47 | 2022-03-03 ✅ Patent 11,332,525 granted on 2022-05-17

US20220064281A1

Chemistry; metallurgy

Polypeptides comprising immunoglobulin single variable domains targeting TNFA and IL-23

#48 | 2021-12-30

US20210403536A1

Chemistry; metallurgy

TECHNIQUES FOR PREDICTING, DETECTING AND REDUCING ASPECIFIC PROTEIN INTERFERENCE IN ASSAYS INVOLVING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS

#49 | 2021-12-16

US20210388062A1

Chemistry; metallurgy

TECHNIQUES FOR PREDICTING, DETECTING AND REDUCING ASPECIFIC PROTEIN INTERFERENCE IN ASSAYS INVOLVING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS

#50 | 2021-12-16

US20210388061A1

Chemistry; metallurgy

TECHNIQUES FOR PREDICTING, DETECTING AND REDUCING ASPECIFIC PROTEIN INTERFERENCE IN ASSAYS INVOLVING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS

#51 | 2021-12-02 ✅ Patent 12,479,885 granted on 2025-11-25

US20210371457A1

Chemistry; metallurgy

CHROMATOGRAPHY-FREE ANTIBODY PURIFICATION METHOD

#52 | 2021-09-02 ✅ Patent 11,319,364 granted on 2022-05-03

US20210269515A1

Chemistry; metallurgy

Immunoglobulin variable domains

#53 | 2021-09-02 ✅ Patent 11,312,765 granted on 2022-04-26

US20210269514A1

Chemistry; metallurgy

Immunoglobulin variable domains

#54 | 2021-08-26 ✅ Patent 11,485,777 granted on 2022-11-01

US20210261653A1

Chemistry; metallurgy

Immunoglobulin variable domains

#55 | 2021-07-15 ✅ Patent 11,208,476 granted on 2021-12-28

US20210214431A1

Chemistry; metallurgy

Polypeptides comprising immunoglobulin single variable domains targeting IL-13 and TSLP

#56 | 2021-06-24 ✅ Patent 11,753,465 granted on 2023-09-12

US20210188967A1

Chemistry; metallurgy

Nucleic acids encoding polypeptides against IL-23

#57 | 2021-06-24

US20210188965A1

Chemistry; metallurgy

POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS TARGETING IL-13 AND TSLP

#58 | 2021-06-24

US20210188963A1

Chemistry; metallurgy

POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS TARGETING TNFA AND IL-23

#59 | 2021-05-13 ✅ Patent 11,858,997 granted on 2024-01-02

US20210139587A1

Chemistry; metallurgy

Amino acid sequences that modulate the interaction between cells of the immune system

#60 | 2021-04-22 ✅ Patent 11,603,401 granted on 2023-03-14

US20210115117A9

Chemistry; metallurgy

Aggrecan binding immunoglobulins

#61 | 2021-03-25 ✅ Patent 11,220,539 granted on 2022-01-11

US20210087261A1

Chemistry; metallurgy

Immunoglobulin variable domains

#62 | 2021-02-18 ✅ Patent 11,851,480 granted on 2023-12-26

US20210047392A1

Chemistry; metallurgy

Method for the production of immunoglobulin single variable domains

#63 | 2021-01-14 ✅ Patent 11,813,307 granted on 2023-11-14

US20210008160A1

Human necessities

Polypeptides binding ADAMTS5, MMP13 and aggrecan

#64 | 2020-10-08 ✅ Patent 11,261,260 granted on 2022-03-01

US20200317802A1

Chemistry; metallurgy

ADAMTS binding immunoglobulins

#65 | 2020-09-10 ✅ Patent 11,332,519 granted on 2022-05-17

US20200283509A1

Chemistry; metallurgy

Serum albumin binders

#66 | 2020-06-18 ✅ Patent 12,129,308 granted on 2024-10-29

US20200190216A1

Chemistry; metallurgy

MMP13 binding immunoglobulins

#67 | 2020-05-21 ✅ Patent 11,840,569 granted on 2023-12-12

US20200157216A1

Chemistry; metallurgy

T cell recruiting polypeptides capable of binding CD123 and TCR alpha/beta

#68 | 2020-05-07

US20200140532A1

Chemistry; metallurgy

AGGRECAN BINDING IMMUNOGLOBULINS

#69 | 2020-04-23 ✅ Patent 11,518,799 granted on 2022-12-06

US20200123233A1

Chemistry; metallurgy

Amino acid sequences directed against envelope proteins of a virus and polypeptides comprising the same for the treatment of viral diseases

#70 | 2020-03-12 ✅ Patent 11,472,871 granted on 2022-10-18

US20200079844A1

Chemistry; metallurgy

Nanobodies against tumor necrosis factor-alpha

#71 | 2019-12-05 ✅ Patent 11,897,944 granted on 2024-02-13

US20190367598A1

Chemistry; metallurgy

Immunoglobulin single variable domain (ISVD) capable of binding to serum albumin

#72 | 2019-12-05 ✅ Patent 11,414,481 granted on 2022-08-16

US20190367597A1

Chemistry; metallurgy

Serum albumin binders

#73 | 2019-12-05 ✅ Patent 11,414,480 granted on 2022-08-16

US20190367596A1

Chemistry; metallurgy

Serum albumin binding immunoglobulin single variable domains

#74 | 2019-10-24 ✅ Patent 11,384,151 granted on 2022-07-12

US20190322753A1

Chemistry; metallurgy

CX3CR1-binding polypeptides comprising immunoglobulin single variable domains

#75 | 2019-05-16 ✅ Patent 11,370,835 granted on 2022-06-28

US20190144531A1

Chemistry; metallurgy

Methods for purification of single domain antigen binding molecules

#76 | 2019-04-25 ✅ Patent 11,149,089 granted on 2021-10-19

US20190119393A1

Chemistry; metallurgy

Method for treating rheumatoid arthritis by administering IL-6 receptor antibodies

#77 | 2019-02-21 ✅ Patent 11,312,788 granted on 2022-04-26

US20190055322A1

Chemistry; metallurgy

PcrV binding single variable domain antibodies

#78 | 2019-01-24 ✅ Patent 10,808,032 granted on 2020-10-20

US20190023796A1

Chemistry; metallurgy

Biological materials related to HER3

#79 | 2019-01-10 ✅ Patent 12,662,550 granted on 2026-06-23

US20190010249A1

Chemistry; metallurgy

STABLE FORMULATIONS OF IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS

#80 | 2018-12-13 ✅ Patent 11,248,055 granted on 2022-02-15

US20180355050A1

Chemistry; metallurgy

Polypeptides inhibiting CD40L

#81 | 2018-11-01 ✅ Patent 11,142,569 granted on 2021-10-12

US20180312578A1

Chemistry; metallurgy

Serum albumin-binding immunoglobulin variable domains

#82 | 2018-01-25 ✅ Patent 11,466,089 granted on 2022-10-11

US20180022811A1

Chemistry; metallurgy

Chemokine receptor binding polypeptides

#83 | 2018-01-18 ✅ Patent 10,618,966 granted on 2020-04-14

US20180016342A1

Chemistry; metallurgy

Methods for the treatment of interleukin-6 receptor-related diseases and disorders

#84 | 2018-01-11

US20180009888A9

Chemistry; metallurgy

TECHNIQUES FOR PREDICTING, DETECTING AND REDUCING ASPECIFIC PROTEIN INTERFERENCE IN ASSAYS INVOLVING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS

#85 | 2017-11-23 ✅ Patent 10,100,110 granted on 2018-10-16

US20170334983A1

Chemistry; metallurgy

Sequences directed against hepatocyte growth factor (HGF) and polypeptides comprising the same for the treatment of cancers and/or tumors

#86 | 2017-11-23 ✅ Patent 11,007,146 granted on 2021-05-18

US20170333344A1

Human necessities

Methods and compositions for the preparation of aerosols

#87 | 2017-09-28 ✅ Patent 11,192,938 granted on 2021-12-07

US20170275361A1

Chemistry; metallurgy

Serum albumin binding proteins containing immunoglobulin single variable domains

#88 | 2017-09-28 ✅ Patent 11,192,937 granted on 2021-12-07

US20170275360A1

Chemistry; metallurgy

Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains

#89 | 2017-09-21 ✅ Patent 10,544,211 granted on 2020-01-28

US20170267752A1

Chemistry; metallurgy

TNF binders

#90 | 2017-09-07

US20170253652A1

Chemistry; metallurgy

INHIBITION OF BONE RESORPTION WITH RANKL BINDING PEPTIDES

#91 | 2017-07-27 ✅ Patent 10,858,445 granted on 2020-12-08

US20170210822A1

Chemistry; metallurgy

Methods of treating TTP with immunoglobulin single variable domains and uses thereof

#92 | 2017-07-27

US20170210789A1

Chemistry; metallurgy

SERUM ALBUMIN BINDING PROTEINS

#93 | 2017-07-06 ✅ Patent 9,745,372 granted on 2017-08-29

US20170190769A1

Chemistry; metallurgy

TNF binders

#94 | 2017-06-15 ✅ Patent 11,078,290 granted on 2021-08-03

US20170166647A1

Chemistry; metallurgy

Amino acid sequences directed against RANK-L and polypeptides comprising the same for the treatment of bone diseases and disorders

#95 | 2017-05-18 ✅ Patent 11,149,086 granted on 2021-10-19

US20170137512A1

Chemistry; metallurgy

KV1.3 binding immunoglobulins

#96 | 2017-05-04 ✅ Patent 12,180,268 granted on 2024-12-31

US20170121399A1

Chemistry; metallurgy

Immunoglobulin variable domains

#97 | 2017-04-20

US20170107302A1

Chemistry; metallurgy

STABILIZED SINGLE DOMAIN ANTIBODIES

#98 | 2017-04-06

US20170096490A1

Chemistry; metallurgy

AMINO ACID SEQUENCES DIRECTED AGAINST RANK-L AND POLYPEPTIDES COMPRISING THE SAME FOR THE TREATMENT OF BONE DISEASES AND DISORDERS

#99 | 2017-04-06

US20170096481A1

Chemistry; metallurgy

SINGLE DOMAIN ANTIBODIES DIRECTED AGAINST TUMOR NECROSIS FACTOR-ALPHA AND USES THEREFOR

#100 | 2017-03-23 ✅ Patent 11,009,511 granted on 2021-05-18

US20170082637A1

Physics

Methods for detecting and/or measuring anti-drug antibodies, in particular treatment-emergent anti-drug antibodies

Also check out ABLYNX NV's (Zwijnaarde, Belgium) applicant profile with 94 patent applications submitted.

AssigneeID:

3818 ⎘