2170 ⎘
Modified animals Animals modified by non-integrating nucleic acids, e.g. antisense, RNAi, morpholino, episomal vector, for non-therapeutic purpose
PROTEIN HAVING NUCLEASE ACTIVITY, FUSION PROTEINS AND USES THEREOF
#2METHOD FOR PROMOTING SEXUAL MATURATION OF FISH
#3METHODS FOR PRODUCING ANTIGEN-BINDING PROTEINS AGAINST FOREIGN ANTIGENS
#4piRNA-BASED CONSTRUCTS FOR REGULATING GENE EXPRESSION AND METHODS OF USE THEREOF
#5BLOCK COPOLYMERS
#6TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS
#7BRAIN TUMOR MODEL
#8METHOD FOR PRODUCING STERILIZED MALE INDIVIDUALS OF MARINE FISH, METHOD FOR PREVENTING REPRODUCTION OF MARINE FISH, AND STERILIZED MALE INDIVIDUALS OF MARINE FISH
#9Multiplexed Genome Editing
#10BLOCK COPOLYMERS
#11METHOD FOR DIAGNOSIS AND TREATMENT OF AUTISM SPECTRUM DISORDER ON BASIS OF ACTIVITY REGULATION MECHANISM OF DORMANT NEURAL STEM CELL
#12Use Of Citicoline In Regulating Respiratory Chain Function Related Protein Level And Preparing Drug For Preventing And Treating Respiratory Chain Dysfunction
#13Novel Structurally Designed shRNAs
#14RNAi COMPOSITIONS AND METHODS FOR GENERATION OF SINGLE SEX OFFSPRING
#15POULTRY CELL IN WHICH A GENE ENCODING A PROTEIN OF INTEREST IS KNOCKED-IN AT EGG WHITE PROTEIN GENE, AND METHOD FOR PRODUCING SAID POULTRY CELL
#16Methods of reducing FUS/TLS- or TDP-43-mediated neuronal cytotoxicity in amyotrophic lateral sclerosis (ALS) by UPF2
#17METHODS FOR PRODUCING ANTIGEN-BINDING PROTEINS AGAINST FOREIGN ANTIGENS
#18SCREENING METHOD FOR SELECTED AMINO-LIPID-CONTAINING COMPOSITIONS
#19PROTEIN HAVING NUCLEASE ACTIVITY, FUSION PROTEINS AND USES THEREOF
#20Method for preparing fish skin mucous gland bioreactor and application thereof
#21Nuclease-mediated nucleic acid modification
#22COMPOSITIONS AND METHODS FOR GENERATING PHYSIOLOGICAL X CHROMOSOME INACTIVATION
#23A RODENT MODEL OF B4GALT1-MEDIATED FUNCTIONS
#24CORRECTION OF DYSTROPHIN EXON 43, EXON 45, OR EXON 52 DELETIONS IN DUCHENNE MUSCULAR DYSTROPHY
#25Methods of genetic mediated engineering of RNAi models
#26Structurally designed shRNAs
#27Isolation of novel AAV's and uses thereof
#28Multiplexed genome editing
#29COMPOSITIONS AND METHODS FOR DETERMINING GENETIC POLYMORPHISMS IN THE TMEM216 GENE
#30Block copolymers
#31METHODS FOR THE PRODUCTION OF STERILE FISH AND OTHER EGG-PRODUCING AQUATIC ANIMALS AND COMPOUNDS FOR USE IN THE METHODS
#32LOSS OF FUNCTION RODENT MODEL OF SOLUTE CARRIER 39 MEMBER 5
#33SCREENING METHOD FOR SELECTED AMINO-LIPID-CONTAINING COMPOSITIONS
#34Multiplexed genome editing
#35MODULATING BIOMARKERS TO INCREASE TUMOR IMMUNITY AND IMPROVE THE EFFICACY OF CANCER IMMUNOTHERAPY
#36Methods of reducing FUS/TLS- or TDP-43-mediated neuronal cytotoxicity by UPF1
#37Stable transformation of a population and a method of biocontainment using haploinsufficiency and underdominance principles
#38Novel Structurally Designed shRNAs
#39METHODS FOR IDENTIFYING MBLAC1-DEPENDENT MOLECULAR NETWORKS
#40METHODS OF A DROSOPHILA MODEL FOR CHRONIC MYELOID LEUKEMIA (CML) TREATMENT
#41EFFICIENT PROTEIN EXPRESSION IN VIVO USING MODIFIED RNA (MOD-RNA)
#42Nucleic acid constructs and methods of using the same
#43Multiplexed genome editing
#44Mouse Models Having a Knockin Scavenger Receptor Class B Type I
#45Isolation of novel AAV's and uses thereof
#46DEVICES, SYSTEMS AND METHODS FOR OPTOGENETIC MODULATION OF ACTION POTENTIALS IN TARGET CELLS
#47EFFICIENT PROTEIN EXPRESSION IN VIVO USING MODIFIED RNA (MOD-RNA)
#48Oncogenic Models Based on Delivery and Use of the CRISPR-Cas Systems, Vectors and Compositions
#49METHOD OF PRODUCING INFERTILE FISH AND EGG-PRODUCING AQUATIC ANIMALS AND OF DELIVERING COMPOUNDS INTO EGGS AND EMBRYOS
#50Antihelminthic medications for pathogenic nematodes
#51Methods of agent delivery into eggs and embryos of egg-producing aquatic animals for drug screening, agent toxicity assay and production of infertile fish
#52Method of producing infertile fish and egg-producing aquatic animals and of delivering compounds into eggs and embryos
#53Multiplexed genome editing
#54Thyroid stimulating hormone receptor peptides and uses thereof
#55Delivery, use and therapeutic applications of the CRISPR-cas systems and compositions for modeling mutations in leukocytes
#56Block copolymers
#57Protein having nuclease activity, fusion proteins and uses thereof
#58SCREENING METHOD FOR SELECTED AMINO-LIPID-CONTAINING COMPOSITIONS
#59Compositions and methods for determining genetic polymorphisms in the TMEM216 gene
#60Host cells with artificial endosymbionts
#61Mouse with D4R iRNA in the intercalating cell mass of the amygdala
#62Gene knockout method
#63Microdystrophin peptides and methods for treating muscular dystrophy using the same
#64Structurally designed shRNAs
#65METHODS FOR BREAKING IMMUNOLOGICAL TOLERANCE USING MULTIPLE GUIDE RNAS
#66RECOMBINANT HBV CCCDNA, THE METHOD TO GENERATE THEREOF AND THE USE THEREOF
#67Method for Preventing or Treating a Protein Aggregation Disease
#68Isolation of novel AAV's and uses thereof
#69Isolation of novel AAV's and uses thereof
#70All sterile males of culicine mosquitoes: a method of creation
#71METHOD OF GENERATING STERILE TERMINAL SIRES IN LIVESTOCK AND ANIMALS PRODUCED THEREBY
#72NOVEL GERM CELL ABLATION COMPOUNDS AND USES THEREOF
#73Eukaryotic cells with artificial endosymbionts for multimodal detection
#74Metabolism-based drug screening platform in bioengineered zebrafish
#75Light-sensitive ion-passing molecules
#76Method of producing infertile fish and egg-producing aquatic animals and of delivering compounds into eggs and embryos
#77Biological control of insects
#78Block copolymers
#79Eukaryotic cells with artificial endosymbionts for multimodal detection
#80Methods of Mutating, Modifying or Modulating Nucleic Acid in a Cell or Nonhuman Mammal
#81GENETICALLY MODIFIED RAT MODELS FOR PHARMACOKINETICS
#82GENETICALLY MODIFIED RAT MODELS FOR DRUG METABOLISM
#83GENETICALLY MODIFIED RAT MODELS FOR PAIN
#84Isolation of novel AAV's and uses thereof
#85Maternally induced sterility in animals
#86Devices, systems and methods for optogenetic modulation of action potentials in target cells
#87Transgenic Animals With Customizable Traits
#88RNA sequence-specific mediators of RNA interference
#89ANIMAL MODEL RESISTANT TO HEARING LOSS
#90Proteins with modified glycosylation and methods of production thereof
#91METHODS FOR PRODUCING FISH WITH HIGH LIPID CONTENT
#92Eukaryotic cells with artificial endosymbionts for multimodal detection
#93Methods of reducing TDP-43-mediated neuronal cytotoxicity in amyotrophic lateral sclerosis by a UPF1 polypeptide or polynucleotide
#94Baculoviral DNA elements for the expression of recombinant proteins in a host insect
#95Structurally designed shRNAs
#96Method of treating a metabolic disorder induced by obesity in a subject in need thereof by administering MK2/3 inhibitors
#97Protein having nuclease activity, fusion proteins and uses thereof
#98Recombinant baculovirus and use thereof
#99Germ cell ablation compounds and uses thereof
#100Modified viral structural protein with antiviral activity
#101Epitope and its use of hepatitis B virus surface antigen
#102Efficient protein expression in vivo using modified RNA (MOD-RNA)
#103Compositions and methods for determining genetic polymorphisms in the TMEM216 gene
#104Micro-RNAs of the miR-15 family modulate cardiomyocyte survival and cardiac repair
#105Structurally designed shRNAs
#106Regulatory proteins and inhibitors
#107Light-sensitive ion-passing molecules
#108Light-sensitive ion-passing molecules
#109MODULATORS OF PROTEASOME ACTIVITY
#110METHOD AND SYSTEM FOR MAPPING SYNAPTIC CONNECTIVITY USING LIGHT MICROSCOPY
#111Light-sensitive ion-passing molecules
#112Modulation of oocyte meiotic progression and oocyte activation
#113Maternally induced sterility in animals
#114Method for acquiring genetically identical gamete from lethal fish haploid-derived germ cell via germ line chimera
#115KNOCK DOWN MODEL OF DICKKOPF HOMOLOGUE 3 (Dkk3) FOR ASSESSING ROLE OF SAID Dkk3 IN SPERMATOGENESIS AND SEX REVERSAL
#116Compositions and methods for determining genetic polymorphisms in the TMEM216 gene
#117Identification of RNAI targets and use of RNAI for rational therapy of chemotherapy-resistant leukemia and other cancers
#118Methods of Modulating the Sex of Avians
#119SCREENING METHOD FOR SELECTED AMINO LIPID-CONTAINING COMPOSITIONS
#120THERAPEUTIC USE OF A GROWTH FACTOR, NSG33
#121Genetically Modified Rat Models for Pain
#122INCREASING LIFESPAN BY MODULATION OF WWP-1 AND UBC-18
#123Compositions And Methods Of Inhibiting NADPH Oxidase Expression
#124RNA sequence-specific mediators of RNA interference
#125Insulin-like gene in prawns and uses thereof
#126RNA sequence-specific mediators of RNA interference
#127Structurally designed shRNAs
#128Genome editing of a locus using zinc-finger nucleases
#129RAPID METHOD FOR GENERATING GENE KNOCK DOWN MODEL
#130RNA sequence-specific mediators of RNA interference
#131ANIMAL MODEL FOR PARKINSON'S DISEASE
#132ShRNA gene therapy for treatment of ischemic heart disease
#133RNA sequence-specific mediators of RNA interference
#134RNA sequence-specific mediators of RNA interference
#135HDAC4 nucleic acid administration to treat retinal disease
#136Genome editing of a locus using nucleases
#137RNA sequence-specific mediators of RNA interference
#138RNA sequence-specific mediators of RNA interference
#139RNA sequence-specific mediators of RNA interference
#140METHODS FOR PRODUCING FISH WITH HIGH LIPID CONTENT
#141Oligoribonucleotide inhibitors of Nrf2 and methods of use thereof for treatment of cancer
#142METHOD FOR TREATING AND PREVENTING RADIATION DAMAGE USING GENETICALLY MODIFIED MESENCHYMAL STEM CELLS
#143PIRNA AND USES RELATED THERETO
#144AGENT FOR PROMOTING NEURONAL DIFFERENTIATION AND METHOD THEREFOR
#145Genetically Modified Rat Models for Pharmacokinetics
#146TREATMENT OF SURGICAL ADHESIONS
#147RAB3B for treatment and prevention of Parkinson's disease
#148SCREENING METHOD FOR SELECTED AMINO LIPID-CONTAINING COMPOSITIONS
#149Upregulation of opioid receptors for management
#150Crustacean androgenic gland hormone, associated peptides, and use thereof
#151Genetically Modified Rat Models for Drug Metabolism
#152TRYPANOSOME RESISTANT NON-HUMAN TRANSGENIC ANIMAL
#153Insulin-like gene of prawns and uses thereof
#154Treatment of squamous cell carcinoma with HSP27 antisense oligonucleotides and radiotherapy
#155Micro-RNAS of the MIR-15 family modulate cardiomyocyte survival and cardiac repair
#156Intracellular pH sensor using nucleic acid assemblies
#157TUMOR SUPPRESSOR GENE SCREENING USING RNA INTERFERENCE LIBRARIES AND METHOD OF TREATMENT
#158COMPOSITIONS AND METHODS FOR INHIBITING NADPH OXIDASE EXPRESSION
#159METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER
#160METHODS AND COMPOSITIONS RELATED TO DLK-1 AND THE P38 MAPK PATHWAY IN NERVE REGENERATION
#161RNA Interference Mediated Inhibition of Cyclic Nucleotide Type 4 Phosphodiesterase (PDE4B) Gene Expression Using Short Interfering Nucleic Acid (siNA)
#162Isolation of novel AAV'S and uses thereof
#163METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEUROLOGICAL DISEASE
#164RNA Interference Mediated Inhibition of Cyclic Nucleotide Type 4 Phosphodiesterase (PDE4B) Gene Expression Using Short Interfering Nucleic Acid (siNA)
#165Growth differentiation factor-11
#166Transgenic Zebrafish
#167RNAi Therapeutics for Treatment of Eye Neovascularization Diseases
#168Transgenic mouse model of B cell malignancy
#169Oligoribonucleotide inhibitors of NRF2 and methods of use thereof for treatment of cancer
#170Cre-lox based gene knockdown constructs and methods of use thereof
#171RNA sequence-specific mediators of RNA interference
#172ANTIFIBROTIC THERAPY
#173Increasing lifespan by modulation of WWP-1 and UBC-18
#174piRNA and uses related thereto
#175ZEBRAFISH MODEL OF MLL LEUKEMOGENESIS
#176Angiogenesis Affecting Polypeptides, Proteins, and Composition, and Methods of Use Thereof
#177ANTI-TUMOR VACCINES DELIVERED BY DENDRITIC CELLS DEVOID OF INTERLEUKIN-10
#178Method for activating efferent sympathetic nerves innervating adipose tissues to improve obesity and symptoms associated therewith
#179Tumor mouse models using lentiviral vectors
#180Method for treating asthma and chronic obstructive pulmonary disease (COPD) comprising administering FGF2
#181Treatment of parkinson's disease and related disorders
#182RNA sequence-specific mediators of RNA interference
#183Polycationic sterol derivatives as transfection agents
#184Therapeutic use of a growth factor, NsG33
#185RNA sequence-specific mediators of RNA interference
#186RNA sequence-specific mediators of RNA interference
#187RNA sequence-specific mediators of RNA interference
#188RNA sequence-specific mediators of RNA interference
#189Models for viral-based cancer therapy
#190Methods and compositions for the treatment of neurological disease