2178 ⎘
Genetically modified animals
Ion channel
#302Transgenic non-human animals for pharmacological and toxicological studies
#303Production of humanized antibodies in transgenic animals
#304Perlecan transgenic animals and methods of identifying compounds for the treatment of amyloidoses
#305Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders
#306Chimeric mouse having an immune system constructed with human CD34+ cells and use thereof
#307Transgenic mouse expressing a polynucleotide encoding human tissue factor
#308Using cytosine deaminases to diminish retroelement transfer from pigs to humans
#309Uses for Eph receptor antagonists and agonists
#310Tau hyperphosphorylation in transgenic mice expressing the APP double mutation
#311Transgenic rodents as animal models for modulation of B1 bradykinin receptor protein
#312Lysosomal proteins produced in the milk of transgenic animals
#313Multivalent entrain-and-amplify immunotherapeutics for carcinoma
#314Cloning of transgenic unglulates comprising artificial chromosomes
#315SCREENING SYSTEMS AND METHODS FOR IDENTIFYING MODULATORS OF XENOBIOTICMETABOLISM
#316Treatment of hemophilia with human Factor IX produced in mammary tissue of transgenic mammals
#317Intervertebral Disc Repair, Methods and Devices Therefor
#318Transgenic Alzheimer's mouse model vectors and uses thereof
#319Therapeutic agent for fibromyalgia
#320Animal models of long QT syndrome and uses thereof
#321Production of hSA-linked butyrylcholinesterases in transgenic mammals
#322Methods of treatment of feeding disorders or disorders of glucose uptake and for modifying metabolism and identifying therapeutic reagents therefor
#323Genetically modified non-human mammals and cells
#324Porcine uroplakin II promoter and the production method of useful proteins using said promoter
#325Gene-targeted animal model of apolipoprotein E4 domain interaction and uses thereof
#326Transgenic mice expressing human CD20 and/or CD16
#327Method and system for introducing a gene into a human stem cell
#328Custom-made meganuclease and use thereof
#329Heterologous antibodies which bind human CD4
#330Transgenic mice expressing human cd20
#331Transgenically produced non-secreted proteins
#332Transgenic nonhuman mammals producing fibrinogen in milk and methods of producing fibrin
#333Transgenic animals as models for neurodegenerative disease
#334Truncated tau proteins
#335Artificial human chromosome containing human antibody a light chain gene
#336Methods and compositions for the generation of antibodies
#337Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof
#338Method of expressing gene in transgenic birds using retrovirus vector and transgenic birds thus obtained
#339Transgenic animals for producing specific isotypes of human antibodies via non-cognate switch regions
#340Ungulates with genetically modified immune systems
#341Animal models
#342Methods of identifying modulators of NMUR2-mediated activity
#343Method for rendering a system immunologically compatible utilizing a nucleic acid construct, a nucleic acid construct for inhibiting or regulating the function of an immune response (Ir) gene and an immunologically compatible system containing a nucleic acid construct for inhibiting or regulating the function of an immune response (Ir) gene
#344Suppression of endogenous immunoglobulin expression
#345Expression of xenogenous (human) immunoglobulins in cloned, transgenic ungulates
#346Expression of xenogenous (human) immunoglobulins in cloned, transgenic ungulates
#347Fish disease models and uses thereof
#348Transgenic animal expressing alzheimer's tau protein
#349Immunologically privileged cells and uses thereof
#350Hepatic cirrhosis model animal and method of constructing the same
#351Mutation associated with epilepsy
#352Expression system for stem-loop rna molecule having rnai effect
#353Gene reactivation by somatic hypermutation
#354Treatment of neurodegenerative conditions with nimesulide
#355Therapeutic methods employing PAI-1 inhibitors and transgenic non-human animal for screening candidate PAI-1 inhibitors
#356Therapeutic retroviral vectors for gene therapy
#357Tissue specific expression of exogenous proteins in transgenic chickens
#358Human MEKK proteins, corresponding nucleic acid molecules and uses therefor
#359Diagnostic and therapeutic use of ensadin-0477 gene and protein for neurodegenerative diseases
#360Therapeutic agent for fibromyalgia
#361Transgenic animals and uses thereof
#362Human antibodies derived from immunized xenomice
#363Transgenic transchromosomal rodents for making human antibodies
#364Universal stem cells
#365Transgenic mouse expressing human FcRn protein
#366Human albumin animal models for drug evaluation, Toxicology and immunogenicity studies
#367Transgenic transchromosomal rodents for making human antibodies
#368Humanized immunoglobulin loci
#369Transgenically produced fusion proteins
#370Promoter sequences for corticotropin releasing-factor receptor CRF2α and method of identifying agents that alter the activity of the promoter sequences
#371Human artificial chromosome containing human antibody λ light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmission
#372Vectors having both isoforms of beta-hexosaminidase
#373Means and methods for the specific modulation of target genes in the CNS and the eye and methods for their identification
#374In vitro screening of cellular events using 3d cell culture systems
#375Transgenic pigs carrying both hHO-1 and hDAF transgenes for xenotransplantation
#376Transgenic non-human animals expressing a truncated activin type II receptor
#377Genetically modified non-human mammal cells, procedure for their production and use in toxicity tests
#378IRAK-4: compositions and methods of use
#379Transgenic aves producing human polyclonal antibodies
#380Transgenic production in saliva
#381BAFF, inhibitors thereof and their use in the modulation of B-cell response and treatment of autoimmune disorders
#382Enclosed aquacultural systems for production of purified recombinant proteins
#383Transgenic mouse whose genome comprises an APP having a mutation at amino acid 664
#384Peptide production
#385Exogenous protein expression system in an avian system
#386C1 inhibitor produced in the milk of transgenic mammals
#387Means and methods for the specific inhibition of genes in cells and tissue of the cns and/or eye
#388Growth differentiation factor-8 nucleic acid and polypeptide from aquatic species, and transgenic aquatic species
#389Antibody specific for mutant presenilin 1
#390SIRT6 transgenic non-human animals and assay methods
#391Human CTLA-4 antibodies and their uses
#392Production of recombinant polypeptides by bovine species and transgenic methods
#393Transgenic zebra fish embryo model for hematopoiesis and lymphoproliferative disorders
#394Intervertebral disk repair, methods and devices therefor
#395Somatic cell line
#396Mutated recombinant collagens
#397Expressed ligand-vascular intercellular signaling molecule
#398Production of ungulates, preferably bovines that produce human immunoglobulins
#399Method for the production of an erythropoietin analog-human IgG fusion proteins in transgenic mammal milk
#400Chimeric nonhuman animal
#401FcγRIIa transgenic animal model for autoimmune disease
#402Polynucleotides encoding growth differentiation factor-8
#403Animal model for identifying agents that inhibit or enhance CTLA4 signaling
#404Production of collagen in the milk of transgenic mammals
#405Human G protein-coupled receptors for metabolic-related disorders
#406Transgenesis with humanized immunoglobulin loci
#407Animals and cells containing a mutated alpha2delta gene
#408Expression of polypeptides in rod outer segment membranes
#409Compositions and methods for the treatment and diagnosis of immune disorders
#410Anticoagulant fusion protein anchored to cell membrane
#411Transgenic mice having a human major histocompatability complex (MHC) phenotype, experimental uses and applications
#412Inhibition of PEX in the treatment of metabolic bone diseases
#413Expressed ligand-vascular intercellular signaling molecule
#414Transgenic bovines having reduced prion protein production
#415Expression of polypeptides in rod outer segment membranes
#416P450 gene regulation
#417Generation of xenogeneic antibodies
#418HBM variants that modulate bone mass and lipid levels
#419PERV screening method and use thereof
#420Cell and transgenic animal modelling human antigenic presentation and their uses
#421Expression of dominant negative transmembrane receptors in the milk of transgenic animals
#422Use of transgenic mice for the efficient isolation of novel human monoclonal antibodies with neutralizing activity against primary HIV-1 strains and novel HIV-1 neutralizing antibodies
#423Human antibodies derived from immunized xenomice
#424Animals and cells containing a mutated alpha2/omega1 gene
#425Mouse showing neurofibril change due to senile dementia
#426Transgenic mice expressing heterologous complement receptor type 1 (CR1) molecules on erythrocytes and uses therefor
#427Monitoring APP cleavage in transgenic rodents comprising an APP-Swedish mutation
#428Triple transgenic mouse model of Alzheimer's disease
#429Spinster-like protein genes, expression products, non-human animal model: uses in human metabolic disorders
#430Method of inducing the formation of neurofibrillary tangles in transgenic animals
#431SK3-1B GFP transgenic mouse model for spinocerebellar ataxia and hyperexcitable behavior
#432Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders
#433Vertebrate embryonic pattern-inducing proteins and uses related thereto
#434Methods for modulating hematopoiesis and vascular growth
#435Parkinson's disease model and methods