2187 ⎘
Genetically modified animals; Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
Cathepsin-associated genetically modified nonhuman mammal
#1502Site-specific gene conversion promoter and gene therapeutic
#1503ANGE gene in atopy
#1504Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1505Transgenic Mice Containing Kir3.3 Potassium Channel Gene Disruptions
#1506Ha4,a new osteoblast-and chondrocyte-specific small secreted peptide, compositions and methods of use
#1507Methods of treatment of feeding disorders or disorders of glucose uptake and for modifying metabolism and identifying therapeutic reagents therefor
#1508Kinase suppressor of Ras inactivation for therapy of Ras mediated tumorigenesis
#1509CCR6 chemokine receptor disruptions, compositions and methods relating thereto
#1510Beta-amyloid peptide-binding proteins and polynucleotides encoding the same
#1511Yeast genes that affect viral replication
#1512Metabolic gene polynucleotides and polypeptides and uses thereof
#1513Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1514Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1515Antibodies directed to the testis-specific tubulin tyrosine-ligase-like protein, BGS42
#1516Methods and vectors for making knockout animals
#1517Receptor
#1518Chimeric mouse with regulated bradeion gene expression
#1519Method to enrich for α(1,3)-galactosyltransferase null pig cells
#1520Inducible site-directed mutagenesis through conditional gene rescue
#1521Methods for treatment of pain
#1522PT32 sperm protein, sperm c-Yes, oocyte cytoplasmic c-Yes, and uses thereof
#1523Serine protease BSSP4
#1524Protein Arginine N-Methyltransferase 2 (PRMT-2)
#1525Genetically modified non-human mammals and cells
#1526Transgenic mammal carrying GANP gene transferred thereinto and utilization thereof
#1527Modulation of angiogenesis
#1528Sequences used to identify if a female mammal comprises a mutation in the alpha-fetoprotein sequence(S) or a partial or total deletion of the alpha-fetoprotein sequence(S)
#1529Antibodies specific for sclerostin
#1530Splicing variant of TGF-beta2 and uses thereof
#1531Diagnosis of human glycosylation disorders
#1532Directed complementation
#1533Method of screening for inhibitors of human Fatty Acid-CoA Ligase 4
#1534Diagnostic and therapeutic use of a sulfotransferase for neurodegenerative diseases
#1535Method of diagnosis of type 2 diabetes and early onset thereof
#1536Directed complementation
#1537Transgenic mice containing mGluR7 metabotropic glutamate receptor gene disruptions
#1538Transposase and method of gene modification
#1539Transposase and method of gene modification
#1540Transgenic mice containing lymphoid-specific GPCR gene disruptions
#1541Tr2, tr4, tr2/tr4 double knockouts and uses thereof
#1542Inducible small RNA expression constructs for targeted gene silencing
#1543Transposase and method of gene modification
#1544GABA B1A receptor disruptions, compositions and methods relating thereto
#1545Method of disrupting heme transport in nematodes and of modelling and evaluating eukaryotic heme transport
#1546Targeted transgenesis using the rosa26 locus
#1547Mammalian IAP gene family, primers, probes and detection methods
#1548Methods of treating muscular dystrophy
#1549Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1550Method for preparing anti-MIF antibodies
#1551Methods and compositions for inhibiting neoplastic cell growth
#1552Transgenic mice containing SOCS-5 cytokine signalling suppressor gene disruptions
#1553Transgenic mice containing channel activating protease 1 (CAP1) gene disruptions
#1554Transgenic mice containing deubiquitinated enzyme gene disruptions
#1555Transgenic mice containing MSK2 serine/threonine kinase gene disruptions
#1556Transgenic mice containing adrenocorticotropin hormone receptor gene disruptions
#1557Methods and compositions for screening for modulators of neuronal cell death in Parkinson's disease
#1558Highly efficient gene targeting vectors and methods for gene targeting method forward epithelial cell line
#1559Transgenic mice containing melanocyte stimulating hormone receptor gene disruptions
#1560DNA markers for cattle growth
#1561Protecting cell therapy for neurological disorders including Parkinson's disease
#1562Anti-pro1477 antibodies
#1563Differentiation and/or proliferation modulating agents and uses therefor
#1564Transgenic mice containing lumulus clotting factor protease-like gene disruptions
#1565Visualization of avian eggs
#1566ADAM-like protease disruptions, compositions and methods related thereto
#1567Eukaryotic genes involved in adult lifespan regulation
#1568Mammalian grainyhead transcription factors
#1569Functional assays for cholesterol absorption inhibitors
#1570Transgenic mice containing, cGMP phosphodiesterase gene disruptions
#1571GNG4 gene disruptions, compositions and methods related thereto
#1572Method of screening antiobesity agents and animal model of obesity
#1573Methods and compositions for the generation of antibodies
#1574Malarial animal model having a chimeric human liver
#1575Transgenic mice containing CX2 gene disruptions
#1576Methods for preventing or treating a condition or a disease associated with angiogenesis
#1577TRP6 calcium channel disruptions, compositions and methods related thereto
#1578Transgenic mice containing sulfotransferase gene disruptions
#1579METHODS FOR SUPPORTING AND PRODUCING HUMAN CELLS AND TISSUES IN NON-HUMAN MAMMAL HOSTS
#1580Methods and compositions for the treatment and diagnosis of body weight disorders
#1581Compositions and methods for treating female fertility
#1582Transgenic mice containing anaphylatoxin C3a gene disruptions
#1583OGR1 gene disruptions, compositions and methods relating thereto
#1584Transgenic mice containing tryptase gene disruptions
#1585Transgenic mice containing chordin gene disruptions
#1586ANKTM1, a cold-activated TRP-like channel expressed in nociceptive neurons
#1587Selective inhibition of rock1 in cardiac therapy
#1588Method of detecting bone paget's disease
#1589Transgenic mice containing retinoid X receptor interacting protein gene disruptions
#1590Protein tyrosine phosphatase RPTP-beta disruptions, compositions and methods relating thereto
#1591Proteins involved in the regulation of energy homeostasis
#1592Transgenic animals for producing specific isotypes of human antibodies via non-cognate switch regions
#1593Toll/interleukin-1 receptor adapter protein (TIRAP)
#1594Ungulates with genetically modified immune systems
#1595Mammalian IAP gene family, primers, probes, and detection methods
#1596RAG polypeptides, nucleic acids, and their use
#1597V1a arginine vasopressin receptor disruptions, compositions and methods relating thereto
#1598Assay methods for identifying RE2-like antagonists, methods of use, and non-human transgenic animals
#1599Knockout mice and their use
#1600Methods of identifying modulators of NMUR2-mediated activity
#1601Method for rendering a system immunologically compatible utilizing a nucleic acid construct, a nucleic acid construct for inhibiting or regulating the function of an immune response (Ir) gene and an immunologically compatible system containing a nucleic acid construct for inhibiting or regulating the function of an immune response (Ir) gene
#1602Methods for increasing the diversity of monoclonal antibodies produced against an antigen
#1603Prostacyclin-stimulating Factor-2
#1604Protein kinases
#1605Assay methods for identifying modulators of OPSDL3 and transgenic knockouts
#1606Expression of xenogenous (human) immunoglobulins in cloned, transgenic ungulates
#1607Expression of xenogenous (human) immunoglobulins in cloned, transgenic ungulates
#1608Glucose and/or fructose transporter naglt1 and its gene
#1609CYT28 serpentine receptor disruptions, compositions and methods relating thereto
#1610Delta opioid receptor disruptions, compositions and methods related thereto
#1611Transgenic mice containing glucocorticoid-induced receptor gene disruptions
#1612Method for determining genotoxicity
#1613Immunologically privileged cells and uses thereof
#1614Calpain large subunit (n-CL4) cysteine protease gene disruptions, and compositions and methods related thereto
#1615Transgenic mice containing NTTP1 phosphatase gene disruptions
#1616Transgenic mice containing beta3GalT2 gene disruptions
#1617Transgenic mice containing TMEM3 beta-1,3-N-acetylglucosaminyltransferase gene disruptions
#1618Lymphocyte surface receptor that binds CAML and methods of use thereof
#1619Methods and compositions for screening for modulators of Parkinson's disease
#1620Transgenic mice containing CLCN4 chloride ion channel gene disruptions
#1621PRO16090 antibodies
#1622Olfactory receptor expression libraries and methods of making and using them
#1623Compositions and methods of using angiopoietin-like 4 protein antibody
#1624Method of treatment and prophylaxis
#1625Method of treatment and an animal model useful for same
#1626Transgenic mice containing Kir5.1 inwardly rectifying potassium channel gene disruptions
#1627Modulation of type IIß phosphoinositide phosphate kinase
#1628Methods for the production of cells and mammals with desired genetic modifications
#1629Prostate cancer therapeutics and diagnostics based on conformers of prostatic cid phosphatase
#1630Expression system for stem-loop rna molecule having rnai effect
#1631Schizophrenia associated genes
#1632Tap-70, a novel marker for epithelial tumors
#1633Isolated clk-1 -/- cells from clk-1 heterozygous animals and their use in treating oxidative stress disorders
#1634Transgenic mice containing GPCR-like gene disruptions
#1635Human cDNA clones comprising polynucleotides encoding polypeptides and methods of their use
#1636Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1637Porcine fgl2
#1638Transgenic mice containing PAFR gene disruptions
#1639Muir-Torre-like syndrome in Fhit deficient mice
#1640Murine genomic polynucleotide sequence encoding a G-protein coupled receptor and methods of use therefor
#1641PRO19624 antibodies
#1642PRO9835 antibodies
#1643Angiogenesis associated proteins, and nucleic acids encoding the same
#1644Prevention of primary Sjogren's Syndrome by ICA69 deficiency
#1645Unique dendritic cell-associated C-type lectins, dectin-1 and dectin-2; compositions and uses thereof
#1646Antibodies to insulin/IGF/relaxin family polypeptides
#1647Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1648Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1649Methods of assessing the risk for the development of sporadic prostate cancer
#1650Animal model for studying hormone signalling and method of modulating the signalling
#1651Meg-3 protein
#1652Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1653Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1654Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1655Conditional disruption of dicer1 in cell lines and non-human mammals
#1656Murine Pten null prostate cancer model
#1657Histamine receptor H3 modified transgenic mice
#1658Method for determining MIF content
#1659Model animals non-responsive to mycobacterial-origin lipoprotein/lipopeptide
#1660Adiponectin-knoucout nonhuman animal
#1661Melusin a muscle specific protein, as a drug target for prevention and treatment of heart failure
#1662Methods of promoting neurite outgrowth with soluble TAJ polypeptides
#1663Carbohydrate determinant selection system for homologous recombination
#1664Vascular endothelial growth factor 2
#1665Methods
#1666Cranial and vertebral defects associated with loss-of-function of Nell
#1667Systems and methods for protein production
#1668Modification of sugar metabolic processes in transgenic cells, tissues and animals
#1669An invertebrate animal model with neurodegenerative phenotype for screening and testing substances
#1670Methods and compositions for cell activation
#1671Mammalian genes involved in rapamycin resistance and tumorgenesis annexin XIII genes
#1672Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1673Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1674Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1675Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1676Transgenic TIEG non-human animals
#1677Transgenic mice containing chemokine receptor 9A gene disruptions
#1678Transgenic animals and uses thereof
#1679Nucleic acid sequences encoding melanoma associated antigen molecules, aminotransferase molecules, ATPase molecules, acyltransferase molecules, pyridoxal-phosphate dependant enzyme molecules and uses therefor
#1680Antagonizing interleukin-21 receptor activity
#1681Secreted protein associated with depression, compositions and methods of use thereof
#1682Transgenic transchromosomal rodents for making human antibodies
#1683Universal stem cells
#1684Artery- and vein-specific proteins and uses therefor
#1685Antibodies to the extracellular domain of human polypeptide and methods of making said antibodies
#1686JNK3 modulators and methods of use
#1687DRG11-responsive (DRAGON) gene family
#1688Immunoglobulins comprising predominantly a MAN3GLCNAC2 glycoform
#1689Transgenic mouse expressing human FcRn protein
#1690Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1691GRP94-based compositions and methods of use thereof
#1692Lysyl oxidase-like 1 (LOXL1) and elastogenesis
#1693Transgenic transchromosomal rodents for making human antibodies
#1694Method of resistance of epilepsy by suppressing the function of alpha 1g protein
#1695Methods and compositions for the treatment of fibrotic conditions & impaired lung function & to enhance lymphocyte production
#1696Immunoglobulins comprising predominantly a Gal2GlcNAc2Man3GlcNAc2 glycoform
#1697Stem cell-derived endothelial cells modified to disrupt tumor angiogenesis
#1698Methods and products related to the production of inner ear hair cells
#1699Noc2 knockout mouse
#1700Cell in which genome is modified
#1701Apo-2DcR
#1702Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1703GPR54 knock-out mammals and screening methods using them
#1704Methods of inhibiting tumor cell proliferation
#1705Endophilin III gene disruptions, compositions and methods related thereto
#1706Vectors having both isoforms of beta-hexosaminidase
#1707Novel 38594, 57312, 53659, 57250, 63760, 49938, 32146, 57259, 67118, 67067, 62092, FBH58295FL, 57255, and 57255alt molecules and uses therefor
#1708Unc-13 in the modulation of neurotransmission and secretion events
#1709Methods and agents for maintaining muscle mass and for preventing muscle atrophy and biomarkers for monitoring same
#1710Means and methods for the specific modulation of target genes in the CNS and the eye and methods for their identification
#1711Smad6 and uses thereof
#1712Therapeutic and diagnostic proteins comprising a SOCS box
#1713Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1714Methods for treating conditions associated with MASP-2 dependent complement activation
#1715CXCR6 chemokine receptor gene disruptions, and compositions and methods related thereto
#1716CYCLIC AMP PHOSPHODIESTERASE 4D7 ISOFORMS AND METHODS OF USE
#1717Human mast cell-expressed membrane proteins
#1718RTD receptor
#1719CARD-4 molecules and uses thereof
#1720Inhibition of gene expression using polynucleotide analogues
#1721Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
#1722Mipp1 homologous nucleic acids and proteins involved in the regulation of energy homeostatis
#1723β-amyloid peptide-binding proteins and polynucleotides encoding the same
#1724Method for preventing or treating cardiac hypertrophy
#1725Therapeutic delivery of adenosine into a tissue
#1726Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1727Diagnostic and therapeutic uses for prox 1
#1728Transgenic mice containing brain-specific membrane-anchored protein gene disruptions
#1729Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1730Transgenic mouse with a targeted deletion of Elovl4 gene
#1731Polypeptides and nucleic acids encoding these and their use for the prevention, diagnosis or treatment of liver disorders and epithelial cancer
#1732Antisense composition and method for treating cancer
#1733DNA encoding mammalian neuropeptide FF (NPFF) receptors and uses thereof
#1734Schizophrenia associated genes, proteins and biallelic markers
#1735Compositions and methods that modulate RNA interference
#1736Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1737Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1738Tissue products derived from porcine animals lacking any expression of functional alpha 1,3 galactosyltransferase
#1739Nonhuman model animal nonresponsive to endotoxin and lipoprotein or lipopeptide
#1740Agouti-related protein deficient cells, non-human transgenic animals and methods of selecting compounds which regulate energy metabolism
#1741Transgenic non-human animals expressing a truncated activin type II receptor
#1742IRAK-4: compositions and methods of use
#1743Mice lacking alpha 1G showing enhanced novelty-seeking and alcohol preference and therapeutic methods for mood disorders by modulating alpha 1G T-type calcium channels
#1744ACE2 activation for treatment of heart, lung and kidney disease and hypertension
#1745Novel compound
#1746Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1747Methods for use of TSLP and agonists and antagonists thereof
#1748Transgenic aves producing human polyclonal antibodies
#1749Method of screening a compound for anxiolytic activity in an apolipoprotein E knockout animal
#1750Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1751Method for functional mapping of an alzheimer's disease gene network and for identifying therapeutic agents for the treatment of alzheimer' s disease
#1752GMG-3 GMG-4 and GMG-6 polynucleotides and polypeptides and uses thereof
#1753Proteases
#1754Human G protein-coupled receptor and modulators thereof for the treatment of ischemic heart disease and congestive heart failure
#1755IEX-1 knockout animals
#1756Nonhuman model animal unresponsive to immunopotentiating synthetic compound
#1757RNA interference mediating small RNA molecules
#1758RNA interference mediating small RNA molecules
#1759Longevity and PAPP-A
#1760Method for producing non-human mammal RNAi phenotype using papilloma virus vector
#1761Insect ammunition vectors and methods of use to identify pesticide targets
#1762Inducible heart attack animal model
#1763Porcine CMP-N-Acetylneuraminic acid hydroxylase gene
#1764Compositions and methods for increasing animal size growth rate
#1765Pancreas-specific proteins
#1766Means and methods for the specific inhibition of genes in cells and tissue of the cns and/or eye
#1767Arrays of PDZ domain polypeptides
#1768Nucleic acid encoding a retinoblastoma binding protein (RBP-7) and polymorphic markers associated with said nucleic acid
#1769Sphingosine-1-phosphate lyase polypeptides, polynucleotides and modulating agents and methods of use therefor
#1770Prion-free transgenic ungulates
#1771Growth differentiation factor-8 nucleic acid and polypeptide from aquatic species, and transgenic aquatic species
#1772Modulation of an innate immune response by altering TRIAL-R signaling
#1773Cells of which genome is modified
#1774In vivo homologous sequence targeting in cells
#1775Methods of identifying modulators of interaction between PDZ domain proteins and PL proteins
#1776Antibody specific for mutant presenilin 1
#1777Secreted and transmembrane polypeptides and nucleic acids encoding the same
#1778In vitro uptake of SPAM 1 (PH-20) by mammalian sperm
#1779Methods of preforming homologous recombination based modification of nucleic acids in recombination deficient cells and use of the modified nucleic acid products thereof
#1780Non-human animal model of oligodendrocyte developmental disorder
#1781Methods and compositions for the treatment of obesity
#1782PT32 sperm protein, sperm c-Yes, oocyte cytoplasmic c-Yes and uses thereof
#1783Artery- and vein-specific proteins and uses therefor
#1784SIRT6 transgenic non-human animals and assay methods
#1785Methods for detecting mutations associated with familial dysautonomia
#1786G-coupled receptor showing selective affinity for ATP
#1787Therapeutic and diagnostic applications based on the role of the CXCR-4 gene in tumorigenesis
#1788Human CTLA-4 antibodies and their uses
#1789Method and apparatus for data transmission using multiple transmit antennas
#1790Knockin non-human animal and tissue-specific MnSOD knockout non-human animal
#1791β-secretase enzyme compositions and methods
#1792Genomic sequence of the 5-Lipoxygenase-activating protein (FLAP), polymorphic markers thereof and methods for detection of asthma
#1793Compositions and methods of modulating cholesterol metabolism
#1794Lysyl oxidase-like 1 (LOXL1) and elastogenesis
#1795Expressed ligand-vascular intercellular signaling molecule
#1796Mouse exhibiting characteristics of Rothmund-Thomson syndrome and preparation method thereof
#1797Lymphocyte surface receptor that binds caml and methods of use thereof
#1798Production of ungulates, preferably bovines that produce human immunoglobulins
#1799Beta-secretase enzyme compositions and methods
#1800Somatic cells, germ cells and cell lines derived from a PTTG knockout rodent