ClassID:

2188

A01K2217/077 - CPC Classification

Classification description:

Genetically modified animals; Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out heterozygous knock out animals displaying phenotype

Recent Application in this class:
#1
20260130347
2026-05-14

TRANSGENIC ANIMALS AND RECOMBINANT HOST CELLS COMPRISING SPECIFIC GENE VARIANTS AND METHODS OF CREATING SAME

#2
20250318509
2025-10-16

TRANSGENIC ANIMAL PHENOTYPING PLATFORM AND USES THEREOF

#3
20250228980
2025-07-17

GENE THERAPY FOR HAPLOINSUFFICIENCY

#4
20240294487
2024-09-05

INHIBITORS OF THE IRE-1/XBP-1 PATHWAY AND METHODS OF USING THEREOF

#5
20230371483
2023-11-23

METHODS AND COMPOSITIONS FOR SEXING AND STERILIZATION IN DROSOPHILA SUZUKII AND AEDES AEGYPTI

#6
20230337647
2023-10-26

TRANSGENIC ANIMAL PHENOTYPING PLATFORM AND USES THEREOF

#7
20230293729
2023-09-21

Gene therapy for haploinsufficiency

#8
20230189771
2023-06-22

LINCRNA-DEFICIENT NON-HUMAN ANIMALS

#9
20230146102
2023-05-11

MONOGENIC OR POLYGENIC DISEASE MODEL ORGANISMS HUMANIZED WITH TWO OR MORE GENES

#10
20230138759
2023-05-04

NON-HUMAN ALZHEIMER'S DISEASE MODEL ANIMAL AND METHOD FOR PRODUCING SAME

#11
20230134819
2023-05-04

MODIFIED SALMON WHICH PRODUCE STERILE OFFSPRING

#12
20220275394
2022-09-01

Application of a fragment of an isolated nucleotide sequence in construction of non-mineralized intermuscular bone of

#13
20220272953
2022-09-01

GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC IL33

#14
20220217956
2022-07-14

Rodent Model Of Increased Bone Mineral Density

#15
20220053740
2022-02-24

A GENETIC MOUSE MODEL OF AUTOIMMUNE ADVERSE EVENTS AND IMMUNE CHECKPOINT BLOCKADE THERAPY

#16
20210392865
2021-12-23

NON-HUMAN ANIMAL EXHIBITING DIMINISHED UPPER AND LOWER MOTOR NEURON FUNCTION AND SENSORY PERCEPTION

#17
20210045366
2021-02-18

Genetically modified non-human animal with human or chimeric LAG3

#18
20200404890
2020-12-31

MODELING TDP-43 PROTEINOPATHY

#19
20200288683
2020-09-17

LOSS OF FUNCTION RODENT MODEL OF SOLUTE CARRIER 39 MEMBER 5

#20
20200261598
2020-08-20

ADENO-ASSOCIATED VIRAL VECTORS FOR TREATING MUCOLIPIDOSIS TYPE II

#21
20200187466
2020-06-18

METHOD FOR CONSTRUCTING MOUSE MODEL WITH CONDITIONAL KNOCKOUT OF TMEM30A GENE FROM PANCREATIC BETA CELL, AND USE THEREOF

#22
20200060246
2020-02-27

Transgenic animal phenotyping platform and uses thereof

#23
20200024247
2020-01-23

Inhibitors of the IRE-1/XBP-1 pathway and methods of using thereof

#24
20190351074
2019-11-21

Gene therapy for haploinsufficiency

#25
20190335725
2019-11-07

GENETICALLY STERILE ANIMALS

#26
20190261610
2019-08-29

NON-HUMAN ANIMAL EXHIBITING DIMINISHED UPPER AND LOWER MOTOR NEURON FUNCTION AND SENSORY PERCEPTION

#27
20190218540
2019-07-18

METHOD FOR ESTABLISHING A NON-HUMAN MAMMALIAN ANIMAL MODEL SUFFERING FROM OBESITY OR RELATED DISEASE AND USE THEREOF

#28
20190141966
2019-05-16

Non-Human Animals Comprising SLC30A8 Mutation And Methods Of Use

#29
20190106710
2019-04-11

Oncogenic Models Based on Delivery and Use of the CRISPR-Cas Systems, Vectors and Compositions

#30
20190076502
2019-03-14

Medical use of CREG protein

#31
20180282761
2018-10-04

Chimaeric Surrogate Light Chains (SLC) Comprising Human VpreB

#32
20180255751
2018-09-13

Delivery, use and therapeutic applications of the CRISPR-cas systems and compositions for modeling mutations in leukocytes

#33
20180243305
2018-08-30

Compositions and methods for treating bone diseases

#34
20180116191
2018-05-03

Method for producing non-human large mammal or fish each capable of producing gamete originated from different individual

#35
20180110829
2018-04-26

TAFA4 COMPOUNDS AND USES THEREOF FOR TREATING PAIN

#36
20180066318
2018-03-08

METHODS OF CHARACTERIZING E-SYT2 INHIBITORS, E-SYT2 INHIBITORS, AND METHODS OF USE

#37
20170360873
2017-12-21

Modulation and detection of a neuronal alternative splicing regulatory network for treatment and diagnosis of neurological disorders

#38
20170191058
2017-07-06

PERFORIN 2 DEFENSE AGAINST INVASIVE AND MULTIDRUG RESISTANT PATHOGENS

#39
20170157218
2017-06-08

Methods of treating fragile X syndrome and related disorders

#40
20170071173
2017-03-16

Method for screening gene expression in lincRNA-deficient mice or rats

#41
20160302398
2016-10-20

Animal model and method for studying gene-gene interactions

#42
20160270377
2016-09-22

Non-human animal exhibiting diminished upper and lower motor neuron function and sensory perception

#43
20160165860
2016-06-16

Domain 5 of CD163 for use in antiviral compositions against PRRS, and transgenic animals

#44
20160113996
2016-04-28

TAFA4 compounds and uses thereof for treating pain

#45
20160083361
2016-03-24

Inhibitors of the IRE-1/XBP-1 pathway and methods of using thereof

#46
20150296757
2015-10-22

Animal model for type 2 diabetes and obesity

#47
20150182495
2015-07-02

Methods and compositions for treating pain

#48
20140359797
2014-12-04

Chimaeric surrogate light chains (SLC) comprising human VpreB

#49
20140255975
2014-09-11

Transgenic pig models of cystic fibrosis

#50
20130291132
2013-10-31

ANF-RGC in-gene knock-out animal

#51
20120189638
2012-07-26

METHOD OF TREATING NEURODEGENERATIVE DISEASE

#52
20120185956
2012-07-19

GLOBAL NAV1.7 KNOCKOUT MICE AND USES

#53
20120039912
2012-02-16

RSPONDIN-3 INHIBITION IN BONE DISORDERS

#54
20110219462
2011-09-08

G-Protein Coupled Receptor 30 (GPR30) transgenic animals as a model for cardiovascular diseases

#55
20110123484
2011-05-26

METHODS AND COMPOSITIONS FOR TREATING FUS1 RELATED DISORDERS

#56
20110030071
2011-02-03

Transgenic Animal Model of Cancer and Methods of Use

#57
20110027187
2011-02-03

Therapeutic or prophylactic agent, detection method and detection agent for metabolic syndrome, and method for screening of candidate compound for therapeutic agent for metabolic syndrome

#58
20110004953
2011-01-06

Method of identifying a compound for preventing and/or treating an autoimmune disease

#59
20100239596
2010-09-23

GRP78 AND TUMOR ANGIOGENESIS

#60
20100137205
2010-06-03

Use of FGF-18 Protein, Target Proteins and Their Respective Encoding Nucleotide Sequences to Induce Cartilage Formation

#61
20090158448
2009-06-18

DNA encoding polypeptide capable of modulating muscle-specific tyrosine kinase activity

#62
20080194472
2008-08-14

Use of Fgf-18 Protein, Target Proteins and Their Respective Encoding Nucleotide Sequences to Induce Cartilage Formation