2189 ⎘
Genetically modified animals Animals comprising multiple alterations of the genome, by transgenesis or homologous recombination, e.g. obtained by cross-breeding
Antibody producing non-human animals
#302IL-17A binding proteins
#303Anti-MUC16 antibodies and uses thereof
#304Transgenic animal for visualization of ATP and use thereof
#305Genetically modified cells, tissues, and organs for treating disease
#306METHODS AND COMPOSITIONS RELATING TO AN EMBRYONIC STEM CELL-BASED TUMOR MODEL
#307Transgenic chicken comprising an inactivated immunoglobulin gene
#308Human lambda light chain mice
#309Transgenic mouse capable of spatial and temporal control of expression and site-specific modification of target protein, production method and uses thereof
#310IMMUNOTHERAPY COMPOSITIONS AND METHODS FOR TREATMENT OF TAUOPATHY AND TRANSGENIC MOUSE
#311Genetically modified non-human animals and methods of use thereof
#312Generation of an inducible pericyte-specific CRE mouse model
#313Identification of a 5-Gene Expression Signature Predicting Clinical Outcome of Patients with Brain Tumors
#314ANTIBODIES, VARIABLE DOMAINS & CHAINS TAILORED FOR HUMAN USE
#315Porcine reproductive and respiratory syndrome virus resistant animals
#316Genetically Modified Non-Human Animals And Methods Of Use Thereof
#317Humanized FcγR mice
#318Mice expressing a limited immunoglobulin light chain repertoire
#319Methods of treating cognitive impairment
#320Co-activation of mTOR and STAT3 pathways to promote neuronal survival and regeneration
#321Non-human animals expressing pH-sensitive immunoglobulin sequences
#322Animal models and therapeutic molecules
#323Non-human animals expressing exogenous terminal deoxynucleotidyltransferase
#324METHODS FOR BREAKING IMMUNOLOGICAL TOLERANCE USING MULTIPLE GUIDE RNAS
#325Humanized light chain mice
#326TRIPLE TRANSGENIC PIGS SUITABLE FOR XENOGRAFT
#327Transgenic mammals and methods of use thereof
#328Transgenic mammals and methods of use thereof
#329SIGNATURES AND PCDETERMINANTS ASSOCIATED WITH PROSTATE CANCER AND METHODS OF USE THEREOF
#330COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF NEUROLOGICAL DISEASE
#331Humanized M-CSF mice
#332Method for producing polyclonal antibodies with improved complement-dependent cytotoxicity
#333GENE EXPRESSION SYSTEM
#334Genetically modified mice and engraftment
#335Transgene construct encoding delta 12 fatty acid
#336Genetically modified major histocompatibility complex mice
#337Methods of treating fragile X syndrome and related disorders
#338ENGINEERING OF HUMANIZED CAR T-CELL AND PLATELETS BY GENETIC COMPLEMENTATION
#339Modulation of BCL11A for treatment of hemoglobinopathies
#340Non-human animals having a humanized lymphocyte-activation gene 3
#341Animal models and therapeutic molecules
#342CO-ACTIVATION OF MTOR AND STAT3 PATHWAYS TO PROMOTE NEURONAL SURVIVAL AND REGENERATION
#343GENETICALLY MODIFIED NON-HUMAN MAMMALS HAVING MODIFIED LIVER CELLS AND/OR TISSUE AND METHODS OF MAKING SAME
#344Human lambda light chain mice
#345METHODS INVOLVING MACROPHAGE TUMOR CELL FUSION HYBRIDS
#346Animal models and therapeutic molecules
#347Animal Models and Therapeutic Molecules
#348TRANSGENIC ANIMALS CAPABLE OF PRODUCING HUMANIZED IGE AT MUCH HIGHER LEVELS THAN MOUSE IGE
#349Animal Models and Therapeutic Molecules
#350Human artificial chromosome containing human antibody lambda light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmission
#351METHOD OF GENERATING STERILE TERMINAL SIRES IN LIVESTOCK AND ANIMALS PRODUCED THEREBY
#352Animal models and therapeutic molecules
#353GERMLINE TRANSMISSION OF CHICKEN PRIMORDIAL GERM CELLS (PGCS)
#354METHOD OF IDENTIFYING THE PRESENCE OF FOREIGN ALLELES IN A DESIRED HAPLOTYPE
#355Humanized IL-6 and IL-6 receptor
#356Genetic modification of rats
#357High-throughput mouse model for optimizing antibody affinities
#358Genetically modified non-human animals and methods of use thereof
#359Treatment of neurological disorders
#360Population control using engineered translocations
#361Methods, Compositions and Systems for Production of Recombinant Spider Silk Polypeptides
#362Animal models and therapeutic molecules
#363Genetically modified non-human animals and methods relating to innate immune system response detection
#364Compositions and methods for treating autoimmune and inflammatory diseases
#365Animal model and cell model developing amyotrophic lateral sclerosis
#366TRANSGENIC PRODUCTION OF HEPARIN
#367Anti-tumor properties of Dickkopf 3b
#368Transgenic transchromosomal rodents for making human antibodies
#369Histidine engineered light chain antibodies and genetically modified non-human animals for generating same
#370Animal model and method for studying gene-gene interactions
#371Transgenic chicken comprising an inactivated immunoglobulin gene
#372Genetically modified non-human animals and methods of use thereof
#373Antibody production
#374Humanized IL-6 and IL-6 receptor
#375Multi-transgenic pigs for diabetes treatment
#376Animal models and therapeutic molecules
#377Non-human mammals for the production of chimeric antibodies
#378Non-human mammals for the production of chimeric antibodies
#379Non-human mammals for the production of chimeric antibodies
#380Non-human mammals for the production of chimeric antibodies
#381Non-human mammals for the production of chimeric antibodies
#382COMMON LIGHT CHAIN MOUSE
#383Animal models and therapeutic molecules
#384Methods of Mutating, Modifying or Modulating Nucleic Acid in a Cell or Nonhuman Mammal
#385GENETICALLY MODIFIED RAT MODELS FOR DRUG METABOLISM
#386GENETICALLY MODIFIED RAT MODELS FOR PAIN
#387Animal models and therapeutic molecules
#388Genetically modified cells, tissues, and organs for treating disease
#389Non-human animals having a humanized cluster of differentiation 47 gene
#390Genetically modified mouse whose genome comprises a humanized CD274 gene
#391Transgenic non-human mammal for producing chimeric human immunoglobulin E antibodies
#392Micro-RNA family that modulates fibrosis and uses thereof
#393Micro-RNA family that modulates fibrosis and uses thereof
#394Micro-RNA family that modulates fibrosis and uses thereof
#395Dosage compensating transgenes and cells
#396Method for measuring cell-to-cell transmission of α-synuclein aggregates using bimolecular fluorescence complementation system and method for screening a substance for preventing or treating neurodegenerative disease using the same
#397Composition comprising ASM inhibitor as active ingredient for preventing or treating degenerative neurological disorders
#398NON HUMAN ANIMAL MODEL FOR ULCERATIVE COLITIS AND ITS MAIN COMPLICATIONS
#399Human lambda light chain mice
#400Method for treating arthritis using IK factor or nucleic acid encoding IK factor
#401Human lambda light chain mice
#402Methods and agents for treating Alzheimer's disease
#403MULTIPLEX GENE EDITING
#404Genetically modified T cell receptor mice
#405TGIF2-induced reprogramming of hepatic cells to pancreatic progenitor cells and medical uses thereof
#406Activation of innate immunity by miRNA for cancer and infection treatment
#407Animal models of cancer
#408Methods, compositions and systems for production of recombinant spider silk polypeptides
#409Proteins with modified glycosylation and methods of production thereof
#410Methods compositions and systems for production of recombinant spider silk polypeptides
#411STABLE TRANSFORMATION OF A POPULATION AND A METHOD OF BIOCONTAINMENT USING HAPLOINSUFFICIENCY AND UNDERDOMINANCE PRINCIPLES
#412Methods of treating, preventing and diagnosing leukemia and other blood diseases and disorders
#413Hybrid light chain mice
#414Treatment of muscular dystrophy
#415Genetically modified non-human animals expressing human EPO
#416Human lambda light chain mice
#417Fibrotic non-human animal, and use thereof
#418Low affinity FCGR deficient mice
#419Non-human animals that make single domain binding proteins
#420Humanized IL-6 and IL-6 receptor
#421Methods of treating cognitive impairment
#422Double knockout (GT/CMAH-KO) pigs, organs and tissues
#423Histidine engineered light chain antibodies and genetically modified non-human animals for generating the same
#424Genetic test and genetic basis for SCID in pigs
#425ADAM6 mice
#426Genetically modified non-human animals and methods of use thereof
#427Transgenic biosensor
#428ADAM6 mice
#429Anti-tumor properties of Dickkopf 3b
#430MOUSE MODEL OF AMYOTROPHIC LATERAL SCLEROSIS AND/OR FRONTOTEMPORAL LOBAR DEGENERATION
#431TRANSGENIC MOUSE EXPRESSING HUMAN ISOGLUTAMINYL CYCLOTRANSFERASE
#432Artificial oocyte activation
#433MATERIALS AND METHODS FOR MAKING A RECESSIVE GENE DOMINANT
#434Transgenic non-human vertebrate for the in vivo production of dual specificity immunoglobulins or hypermutated heavy chain only immunoglobulins
#435Normalization of the enterohepatic circulation in animals with a chimeric humanized liver
#436Urokinase-type plasminogen activator transgenic mouse
#437Methods and compositions for the treatment of insulin-associated medical conditions
#438Genetically modified non-human animals and methods relating to innate immune system response detection
#439Human lambda light chain mice
#440Transgenic non-human vertebrate for the expression of class-switched, fully human, antibodies
#441TRANSGENIC MOUSE EXPRESSING HUMAN LIPOPROTEIN (A) WITH DISABLED VITAMIN C GENE AND ITS USE AS A DISEASE TREATMENT MODEL
#442Methods for making fully human bispecific antibodies using a common light chain
#443Transgenic immunodeficient mouse expressing human SIRP-alpha
#444GENETICALLY MODIFIED RAT MODELS FOR PAIN
#445GENETICALLY MODIFIED RAT MODELS FOR PHARMACOKINETICS
#446Humanized M-CSF mice
#447Animals, repertoires and methods
#448Isolated cells from humanized FcγR mice
#449RAB6KIFL/KIF20A epitope peptide and vaccines containing the same
#450Humanized IL-6 and IL-6 receptor
#451Humanized IL-6 and IL-6 receptor
#452Production of heavy chain only antibodies in transgenic mammals
#453Antibody production
#454Controllable on-off method for fish reproduction
#455Histidine engineered light chain antibodies and genetically modified non-human animals for generating the same
#456Antibody producing non-human mammals
#457Method of treating a metabolic disorder induced by obesity in a subject in need thereof by administering MK2/3 inhibitors
#458Antibody producing non-human mammals
#459Animal models and therapeutic molecules
#460Co-activation of mTOR and STAT3 pathways to promote neuronal survival and regeneration
#461ADAM6 mice
#462Manipulation of immunoglobulin gene diversity and multi-antibody therapeutics
#463Boosting human dendritic cell development, homeostasis and function in xenografted immunodeficient mice
#464Low affinity FCGR deficient mice
#465Humanized Fc gamma R mice
#466Animal models and therapeutic molecules
#467Genetically modified non-human animals and methods of use thereof
#468Animal models and therapeutic molecules
#469Porcine reproductive and respiratory syndrome virus resistant animals
#470Genetically modified mice and engraftment
#471Non-human animals expressing pH-sensitive immunoglobulin sequences
#472Transgenic chicken comprising an inactivated immunoglobulin gene
#473Humanized light chain mice
#474Plasma anti-diabetic NUCB2 peptide (pladin) and uses thereof
#475Antibody production
#476Restricted immunoglobulin heavy chain mice
#477Multifunctional alleles
#478Compositions and methods relating to non-human animals modified to promote production of selected gametes
#479Animal models and therapeutic molecules
#480Animal models and therapeutic molecules
#481Micro-RNA family that modulates fibrosis and uses thereof
#482Micro-RNA family that modulates fibrosis and uses thereof
#483Humanized transgenic animal
#484Non-human animals expressing pH-sensitive immunoglobulin sequences
#485Mice that produce antigen-binding proteins with pH-dependent binding characteristics
#486Histidine engineered light chain antibodies and genetically modified non-human animals for generating the same
#487Transgenic animals and methods of use
#488Conditional Mst overexpressing construct and conditional myostatin overexpressing transgenic mouse
#489Humanized transgenic mouse model
#490Hairless NOD scid mouse
#491Mice expressing a limited immunoglobulin light chain repertoire
#492Humanized universal light chain mice
#493Micro-RNA family that modulates fibrosis and uses thereof
#494Genetically modified major histocompatibility complex animals
#495Humanized light chain mice
#496Regulatory proteins and inhibitors
#497Antibody producing non-human mammals
#498Modulation of BCL11A for treatment of hemoglobinopathies
#499Humanized IL-6 and IL-6 receptor
#500Methods and uses of TIE2 binding and/or activating agents
#501Genetically modified major histocompatibility complex mice
#502Genetically modified mice having humanized TCR variable genes
#503Restricted immunoglobulin heavy chain mice
#504METHOD AND SYSTEM FOR MAPPING SYNAPTIC CONNECTIVITY USING LIGHT MICROSCOPY
#505IN VIVO SCREENING MODELS FOR TREATMENT OF QC-RELATED DISORDERS
#506Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain
#507Transgenic mouse homozygous for chimeric IgH locus
#508Humanized M-CSF mice
#509Use of Follistatin-Like Related Gene (FLRG) to Increase Muscle Mass
#510Genetically modified mice and engraftment
#511Genetically modified mice and engraftment
#512ADAM6 mice
#513Transgenic biosensors
#514TRANSGENIC MICE OVER-EXPRESSING RECEPTOR FOR ADVANCED GLYCATION ENDPRODUCT (RAGE) IN BRAIN AND USES THEREOF
#515Transgenic pig in which HO-1 and TNFR1-Fc are simultaneously expressed, and method for producing same
#516DIAGNOSIS MARKER, DIAGNOSIS METHOD AND THERAPEUTIC AGENT FOR AMYOTROPHIC LATERAL SCLEROSIS, AND ANIMAL MODEL AND CELL MODEL DEVELOPING AMYOTROPHIC LATERAL SCLEROSIS
#517STROMAL INTERACTING MOLECULE KNOCKOUT MOUSE AND USES THEREOF
#518Low affinity FcγR deficient mice
#519METHODS AND SYSTEMS FOR INDUCIBLE ABLATION OF NEURAL CELLS
#520Transparent zebrafish and preparation method thereof
#521ANIMAL MODELS AND THERAPEUTIC MOLECULES
#522METHODS OF MONITORING ENDOPLASMIC RETICULUM (ER) STRESS RESPONSE
#523UBIQUITIN INTERACTING MOTIF PEPTIDES AS CANCER THERAPEUTICS
#524Common Light Chain Mouse
#525METHOD OF TREATING NEURODEGENERATIVE DISEASE
#526DOUBLE MUTANT MOUSE AND CELL LINES
#527Transgenic pig model of cystic fibrosis
#528Genetically modified rat models for severe combined immunodeficiency (SCID)
#529Mouse model for diagnosis of T cell acute lymphoblastic leukemia and for screening of therapeutic agents, and methods of use therefor
#530Compositions and methods relating to non-human animals modified to promote production of selected gametes
#531ANIMAL MODELS AND THERAPEUTIC MOLECULES
#532GENOME EDITING OF GENES INVOLVED IN ADME AND TOXICOLOGY IN ANIMALS
#533GENOMIC EDITING OF GENES INVOLVED IN MACULAR DEGENERATION
#534Genetically Modified Rat Models for Pain
#535Targeted and regional cellular ablation in zebrafish
#536Methods for modulating embryonic stem cell differentiation
#537DHX36 / RHAU KNOCKOUT MICE AS EXPERIMENTAL MODELS OF MUSCULAR DYSTROPHY
#538Polynucleotides encoding a human TRIM-Cyp fusion polypeptide, compositions thereof, and methods of using same
#539BOOSTING HUMAN DENDRITIC CELL DEVELOPMENT, HOMEOSTASIS AND FUNCTION IN XENOGRAFTED IMMUNODEFICIENT MICE
#540Transgenic non-human animals expressing human blood clotting factors and uses thereof
#541Use of IL-17 Polypeptides for Use in the Prevention or Treatment of Atherosclerosis
#542Hybrid light chain mice
#543Human lambda light chain mice
#544IN VIVO SCREENING MODELS FOR TREATMENT OF isoQC-RELATED DISORDERS
#545Methods for Conditional and Inducible Transgene Expression to Direct the Development of Embryonic, Embryonic Stem, Precursor and Induced Pluripotent Stem Cells
#546Common Light Chain Mouse
#547Non-human animal model for amyotrophic lateral sclerosis (ALS) with loss-of-TDP-43 function
#548ANTIBODY PRODUCTION
#549Methods of treating cognitive impairment
#550Mouse having human leukemic stem cell and leukemic non-stem cell amplified therein, and method for production thereof
#551Animal Model for Osteoarthritis and Intervertebral Disc Disease
#552Recombinant vaccinia virus having hepatitis C virus gene
#553Signatures and PCDeterminants Associated with Prostate Cancer and Methods of Use Thereof
#554NUCLEAR RECEPTOR SENSOR SYSTEM IN TRANSGENIC ANIMAL
#555RAB6KIFL/KIF20A epitope peptide and vaccines containing the same
#556Humanized FcgR mice
#557Methods and systems for identifying modulators of longevity
#558VACCINE COMPOSITIONS
#559Non-human mammals for the production of chimeric antibodies
#560Evaluation/screening method for diseases associated with D-amino acid utilizing DAO1-/-mouse
#561Genetically modified mice and engraftment
#562Common light chain mouse
#563Modulation of BCL11A for treatment of hemoglobinopathies
#564PROBE FOR VISUALIZING NEURAL ACTIVITY
#565Humanized FcγR mice
#566Genetically Modified Rat Models for Pharmacokinetics
#567Targeting TGF-β as a therapy for Alzheimer's disease
#568TRIPLE TRANSGENIC MOUSE MODEL OF AUTOIMMUNE DISEASE AND NF-KAPPA B IN VIVO IMAGING
#569Transgenic mice over-expressing receptor for advanced glycation endproduct (RAGE) in brain and uses thereof
#570Efficient Insertion of DNA Into Embryonic Stem Cells
#571Multifunctional Alleles
#572METHOD FOR PRODUCING FOUNDER ANIMAL FOR REPRODUCING ANIMAL HAVING LETHAL PHENOTYPE CAUSED BY GENE MODIFICATION
#573HEAT SHOCK PROTEIN DEFICIENCIES AS MODEL SYSTEMS FOR BRAIN PATHOLOGY AND CANCER
#574Recombinant non-human mammalian model for hepatitis infection and immunopathogenesis
#575Multi-transgenic pigs for diabetes treatment
#576Genetically Modified Rat Models for Drug Metabolism
#577COMPOSITIONS AND METHODS FOR CANCER GENE DISCOVERY
#578Transgenic Animal Model of Cancer and Methods of Use
#579Therapeutic or prophylactic agent, detection method and detection agent for metabolic syndrome, and method for screening of candidate compound for therapeutic agent for metabolic syndrome
#580PRODUCTS AND THEIR USE FOR THE DIAGNOSIS, PREVENTION AND/OR CARE OF HUMAN AND/OR ANIMAL PATHOLOGIES CHARACTERISED BY THE ANOMALOUS DEPOSITION OF B-AMYLOID AND/OR AMYLOID-LIKE SUBSTANCE IN HUMAN AND/OR ANIMAL ORGANS AND TISSUES, AND SCREENING METHOD FOR DETERMINING THE RISK OF SUCH PATHOLOGIES
#581Method of identifying a compound for preventing and/or treating an autoimmune disease
#582METHODS FOR PRODUCTION OF ATRIAL PROGENITORS AND THEIR DIFFERENTIATION INTO SMOOTH MUSCLE CELLS AND CARDIOMYOCYTES
#583Transgenic trasnchromosomal rodents for making human antibodies
#584STROMAL INTERACTING MOLECULE KNOCKOUT MOUSE AND USES THEREOF
#585Inhibitors of Caspase I-Dependent Cytokines in the Treatment of Neurodegenerative Disorders
#586QUADRUPLE TRANSGENIC NON-HUMAN ANIMAL
#587Cardiac Conduction System (CCS) Progenitor Cells and Uses Thereof
#588Micro-RNA family that modulates fibrosis and uses thereof
#589LexA-based chemical-inducible gene expression system for use in transgenic animals
#590Mouse models with enhanced essential tremor and preparation method thereof
#591Regulator of ephrin-Eph receptor signaling and mouse having abnormal ephrin-Eph receptor signaling mechanisms
#592Compositions and methods for the treatment and prevention of ulcerative colitis and colon cancer and screening methods to identify same
#593METHOD FOR TARGETED CELL ABLATION
#594Targeted and regional cellular ablation in zebrafish
#595Method of deleting an IgM gene in an isolated rat cell
#596Methods of increasing muscle mass using follistatin-like related gene (FLRG)
#597Conditional Mst overexpressing construct and conditional myostatin overexpressing transgenic mouse
#598Antibody producing non-human mammals
#599Use of FGF-18 Protein, Target Proteins and Their Respective Encoding Nucleotide Sequences to Induce Cartilage Formation
#600ANIMAL MODEL FOR THE SELECTION AND VALIDATION OF AGENTS ACTIVE AGAINST PULMONARY EMPHYSEMA AND COLORECTAL CANCER