ClassID:

20430

A61K31/527 - CPC Classification

Classification description:

Medicinal preparations containing organic active ingredients; Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two nitrogen atoms as the only ring heteroatoms, e.g. piperazine; Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim spiro-condensed

Recent Application in this class:
#1
20260125392
2026-05-07

URACIL DERIVATIVES HAVING VIRUS REPLICATION INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

#2
20260103471
2026-04-16

CYCLIC UREA THIAZOLYL COMPOUNDS FOR TREATMENT OF HSV

#3
20260092071
2026-04-02

COMPOUNDS AND COMPOSITIONS AS SMARCA2/4 DEGRADERS AND USES THEREOF

#4
20260070917
2026-03-12

CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF

#5
20260060970
2026-03-05

Use of a Therapeutic Agent with Phosphodiesterase-7 Inhibitory Activity for the Treatment and Prevention of Diseases Associated with Chronic Fatigue, Exhaustion and/or Exertional Intolerance

#6
20260060941
2026-03-05

ENGAGING THE CERVICAL SPINAL CORD CIRCUITRY TO RE-ENABLE VOLITIONAL CONTROL OF HAND FUNCTION IN TETRAPLEGIC SUBJECTS

#7
20260048059
2026-02-19

USE OF SUBSTITUTED BENZOXAZOLE AND BENZOFURAN COMPOUNDS FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANC

#8
20260008777
2026-01-08

INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE

#9
20250376478
2025-12-11

CYCLIC UREA THIAZOLYL COMPOUNDS FOR TREATMENT OF HSV

#10
20250361213
2025-11-27

1,4-DIHYDROQUINAZOLINONE COMPOUNDS AND USES THEREOF

#11
20250340560
2025-11-06

SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINES AS BRUTON'S TYROSINE KINASE MODULATORS

#12
20250188057
2025-06-12

NON-AROMATIC CYCLIC-PYRIMIDINE ANALOGS AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS

#13
20250154153
2025-05-15

DIHYDROIMIDAZO-PYRIMIDINONE COMPOUNDS AS LP-PLA2 INHIBITORS AND USE THEREOF

#14
20250154138
2025-05-15

Small Molecule IL-17A Modulators

#15
20250154111
2025-05-15

1,4-DIHYDROQUINAZOLINONE COMPOUNDS AND USES THEREOF

#16
20250092056
2025-03-20

URACIL DERIVATIVES HAVING VIRUS REPLICATION INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

#17
20250034161
2025-01-30

SPIROCYCLIC COMPOUND AS KRAS-G12C INHIBITOR

#18
20250026765
2025-01-23

SPIROHETEROCYCLE DERIVATIVE HAVING SEROTONIN RECEPTOR BINDING ACTIVITY

#19
20250019385
2025-01-16

SPIROCYCLIC ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER

#20
20240374541
2024-11-14

ENGAGING THE CERVICAL SPINAL CORD CIRCUITRY TO RE-ENABLE VOLITIONAL CONTROL OF HAND FUNCTION IN TETRAPLEGIC SUBJECTS

#21
20240285645
2024-08-29

MODULATORS OF TOLL-LIKE RECEPTORS FOR THE TREATMENT OF HIV

#22
20240254128
2024-08-01

SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINES AS BRUTON'S TYROSINE KINASE MODULATORS

#23
20240246995
2024-07-25

PYRIMIDINONE DERIVATIVE AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USE

#24
20240109906
2024-04-04

CDK INHIBITORS

#25
20230390301
2023-12-07

HIGH-ACTIVITY WNT PATHWAY INHIBITOR COMPOUND

#26
20230381189
2023-11-30

TRANSIENT PROTECTION OF NORMAL CELLS DURING CHEMOTHERAPY

#27
20230364098
2023-11-16

HSPC-SPARING TREATMENTS FOR RB-POSITIVE ABNORMAL CELLULAR PROLIFERATION

#28
20230295171
2023-09-21

FUSED HETEROAROMATIC PYRROLIDINONES

#29
20230248733
2023-08-10

HIGHLY ACTIVE ANTI-NEOPLASTIC AND ANTI-PROLIFERATIVE AGENTS

#30
20230241059
2023-08-03

ANTI-NEOPLASTIC COMBINATIONS AND DOSING REGIMENS USING CDK4/6 INHIBITOR COMPOUNDS TO TREAT RB-POSITIVE TUMORS

#31
20230158025
2023-05-25

GALACTOKINASE INHIBITORS

#32
20230110784
2023-04-13

TREATMENT OF ADDICTION AND IMPULSE-CONTROL DISORDERS USING PDE7 INHIBITORS

#33
20230013862
2023-01-19

SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINES AS BRUTON'S TYROSINE KINASE MODULATORS

#34
20230010886
2023-01-12

SHP2 INHIBITORS AND USES THEREOF

#35
20220306634
2022-09-29

FUSED HETEROAROMATIC PYRROLIDINONES

#36
20220296593
2022-09-22

METHODS OF TREATING ELEVATED PLASMA CHOLESTEROL

#37
20220233512
2022-07-28

INHIBITING AN IMMUNE RESPONSE MEDIATED BY ONE OR MORE OF TLR2, RAGE, CCR5, CXCR4 AND CD4

#38
20220062293
2022-03-03

MODULATORS OF TOLL-LIKE RECEPTORS FOR THE TREATMENT OF HIV

#39
20210395259
2021-12-23

CDK INHIBITORS

#40
20210378991
2021-12-09

Engaging the cervical spinal cord circuitry to re-enable volitional control of hand function in tetraplegic subjects

#41
20210299130
2021-09-30

Transient protection of normal cells during chemotherapy

#42
20210267986
2021-09-02

THERAPEUTIC REGIMENS FOR TREATMENT OF CANCER USING ERIBULIN AND SELECTIVE CDK4/6 INHIBITOR COMBINATIONS

#43
20210213022
2021-07-15

HSPC-sparing treatments for RB-positive abnormal cellular proliferation

#44
20210114982
2021-04-22

Indole derivatives and their use as protein kinase inhibitors

#45
20210077498
2021-03-18

TRANSIENT PROTECTION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS AGAINST IONIZING RADIATION

#46
20200375994
2020-12-03

Uses

#47
20200345743
2020-11-05

HIGHLY ACTIVE ANTI-NEOPLASTIC AND ANTI-PROLIFERATIVE AGENTS

#48
20200345742
2020-11-05

Transient protection of normal cells during chemotherapy

#49
20200277300
2020-09-03

CDK inhibitors

#50
20200230140
2020-07-23

N3-substituted iminopyrimidinones as antimalarial agents

#51
20200148690
2020-05-14

Substituted pyrazolo[1,5-a]pyrimidines as Bruton's tyrosine kinase modulators

#52
20190321366
2019-10-24

Modulators of toll-like receptors

#53
20190192519
2019-06-27

Uses

#54
20190183824
2019-06-20

USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS

#55
20190167987
2019-06-06

Engaging the cervical spinal cord circuitry to re-enable volitional control of hand function in tetraplegic subjects

#56
20190167691
2019-06-06

TRANSIENT PROTECTION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS AGAINST IONIZING RADIATION

#57
20190151311
2019-05-23

Anti-neoplastic combinations and dosing regimens using CDK4/6 inhibitor compounds to treat Rb-positive tumors

#58
20190134056
2019-05-09

K-RAS MUTATIONS AND ANTAGONISTS

#59
20190134055
2019-05-09

Treatment of addiction and impulse-control disorders using PDE7 inhibitors

#60
20190125752
2019-05-02

Highly active anti-neoplastic and anti-proliferative agents

#61
20190071399
2019-03-07

Indole derivatives and their use as protein kinase inhibitors

#62
20190070185
2019-03-07

HSPC-sparing treatments for RB-positive abnormal cellular proliferation

#63
20190030031
2019-01-31

Galactokinase inhibitors for the treatment and prevention of associated diseases and disorders

#64
20180360841
2018-12-20

HSPC-sparing treatments for Rb-positive abnormal cellular proliferation

#65
20180360840
2018-12-20

Transient protection of normal cells during chemotherapy

#66
20180303838
2018-10-25

TRANSIENT PROTECTION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS AGAINST IONIZING RADIATION

#67
20180251466
2018-09-06

Substituted pyrazolo[1,5-a]pyrimidines as Bruton's tyrosine kinase modulators

#68
20180235934
2018-08-23

NORADRENERGIC DRUG TREATMENT OF OBSTRUCTIVE SLEEP APNEA

#69
20180221378
2018-08-09

Transient protection of normal cells during chemotherapy

#70
20180169104
2018-06-21

Fused, spirocyclic heteroaromatic compounds for the treatment of bacterial infections

#71
20180141951
2018-05-24

FUSED HETEROAROMATIC PYRROLIDINONES

#72
20180085370
2018-03-29

Modulators of toll-like receptors

#73
20180042928
2018-02-15

Methods and compositions for treating bacterial infection

#74
20180015096
2018-01-18

HIGHLY ACTIVE ANTI-NEOPLASTIC AND ANTI-PROLIFERATIVE AGENTS

#75
20170333440
2017-11-23

Tricyclic lactams for use in HSPC-sparing treatments for Rb-positive abnormal cellular proliferation

#76
20170182043
2017-06-29

Anti-neoplastic combinations and dosing regimens using CDK4/6 inhibitor compounds to treat RB-positive tumors

#77
20170128453
2017-05-11

Uses

#78
20170119774
2017-05-04

Transient Protection of Hematopoietic Stem and Progenitor Cells Against Ionizing Radiation

#79
20170100405
2017-04-13

HSPC-sparing treatments for RB-positive abnormal cellular proliferation

#80
20170073349
2017-03-16

Substituted pyrazolo[1,5-a]pyrimidines as bruton's tyrosine kinase modulators

#81
20170065597
2017-03-09

Transient protection of normal cells during chemotherapy

#82
20170065592
2017-03-09

MODULATORS OF TOLL-LIKE RECEPTORS

#83
20170056405
2017-03-02

Methods and compositions for treating bacterial infection

#84
20170037051
2017-02-09

Transient protection of normal cells during chemotherapy

#85
20170035760
2017-02-09

GALACTOKINASE INHIBITORS FOR THE TREATMENT AND PREVENTION OF ASSOCIATED DISEASES AND DISORDERS

#86
20160310499
2016-10-27

Highly Active Anti-Neoplastic and Anti-Proliferative Agents

#87
20160235977
2016-08-18

Engaging the cervical spinal cord circuitry to re-enable volitional control of hand function in tetraplegic subjects

#88
20160083392
2016-03-24

Substituted imidazo[1,2-b]pyrazoles as bruton'S tyrosine kinase modulators

#89
20160045507
2016-02-18

Method of treating a CNS injury with a PDE1 inhibitor

#90
20160015715
2016-01-21

USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS

#91
20160015713
2016-01-21

Modulators of toll-like receptors

#92
20160008374
2016-01-14

Modulators of toll-like receptors for the treatment of HIV

#93
20150361079
2015-12-17

Spiro-quinazolinone derivatives and their use as positive allosteric modulators of mGluR4

#94
20150336964
2015-11-26

FUSED HETEROAROMATIC PYRROLIDINONES

#95
20150299215
2015-10-22

Spiro ring compound as hepatitis C virus (HCV) inhibitor and uses thereof

#96
20150299212
2015-10-22

Tricyclic lactams for use in HSPC-sparing treatments for RB-positive abnormal cellular proliferation

#97
20150297607
2015-10-22

Tricyclic Lactams for Use in the Protection of Normal Cells During Chemotherapy

#98
20150297606
2015-10-22

Tricyclic Lactams for Use in the Protection of Hematopoietic Stem and Progenitor Cells Against Ionizing Radiation

#99
20150274747
2015-10-01

Substituted heteroaryl compounds and methods of use

#100
20150274733
2015-10-01

Substituted pyrrolo[3,4-d]pyrimidines as kinase inhibitors

#101
20150274705
2015-10-01

Substituted heteroaryl compounds and methods of use

#102
20150274704
2015-10-01

Substituted heteroaryl compounds and methods of use

#103
20150259354
2015-09-17

Substituted pyrazolo[1,5-a]pyrimidines as bruton's tyrosine kinase modulators

#104
20150152118
2015-06-04

Tetrahydroquinazolinone derivatives as PARP inhibitors

#105
20150105374
2015-04-16

Substituted annellated pyrimidines and use thereof

#106
20150087627
2015-03-26

COMBINATION OF KINASE INHIBITORS AND USES THEREOF

#107
20150005295
2015-01-01

4,4-disubstituted-1,4-dihydropyrimidines and the use thereof as medicaments for the treatment of hepatitis B

#108
20140357626
2014-12-04

Hetero-bicyclic derivatives as HCV inhibitors

#109
20140350020
2014-11-27

Ring-fused pyrimidines and triazines and use thereof for the treatment and/or prophylaxis of cardiovascular diseases

#110
20140275067
2014-09-18

Transient protection of normal cells during chemotherapy

#111
20140275066
2014-09-18

Transient protection of normal cells during chemotherapy

#112
20140274896
2014-09-18

Transient Protection of Hematopoietic Stem and Progenitor Cells Against Ionizing Radiation

#113
20140271466
2014-09-18

HSPC-sparing treatments for RB-positive abnormal cellular proliferation

#114
20140179717
2014-06-26

Use of PDE7 inhibitors for the treatment of movement disorders

#115
20130289012
2013-10-31

1,2,4-oxadiazole and 1,2,4-thiadiazole β-lactamase inhibitors

#116
20130267502
2013-10-10

Treatment of addiction and impulse-control disorders using PDE7 inhibitors

#117
20130245031
2013-09-19

Fused heteroaromatic pyrrolidinones

#118
20130116260
2013-05-09

Fused heteroaromatic pyrrolidinones as SYK inhibitors

#119
20120294930
2012-11-22

Combination of mTOR inhibitors and P13-kinase inhibitors, and uses thereof

#120
20110152273
2011-06-23

Fused heteroaromatic pyrrolidinones

#121
20110091388
2011-04-21

USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS

#122
20110052612
2011-03-03

SPIROPIPERIDINE COMPOUND AND MEDICINAL USE THEREOF

#123
20100152176
2010-06-17

Modulators of Muscarinic Receptors

#124
20100143301
2010-06-10

Modulators of toll-like receptors

#125
20100120719
2010-05-13

Lyophilization formulation

#126
20100113486
2010-05-06

Use of PDE7 inhibitors for the treatment of movement disorders

#127
20090253747
2009-10-08

Remedy for sleep disturbance

#128
20090111837
2009-04-30

USE OF PDE7 INHIBITORS FOR THE TREATMENT OF NEUROPATHIC PAIN

#129
20080260643
2008-10-23

USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS

#130
20080176843
2008-07-24

Modulators of muscarinic receptors

#131
20080081820
2008-04-03

Substituted 8′-pyri(MI)dinyl-dihydrospiro-[cycloalkylamine]-pyrimido[1,2-]pyrimidin-6-one derivatives

#132
20070010539
2007-01-11

Substituted 8′-pyri(MI)dinyl-dihydrospiro-[cycloalkylamine]-pyrimido[1,2-]pyrimidin-6-one derivatives

#133
20060019977
2006-01-26

Spiroheterocyclic derivative compounds and drugs comprising the compound as the active ingredient

#134
20050119308
2005-06-02

Remedy for sleep disturbance