ClassID:

20431

A61K31/529 - CPC Classification

Classification description:

Medicinal preparations containing organic active ingredients; Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two nitrogen atoms as the only ring heteroatoms, e.g. piperazine; Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim forming part of bridged ring systems

Recent Application in this class:
#1
20260144795
2026-05-28

SPIROMACROCYCLIC OREXIN 2 RECEPTOR AGONISTS

#2
20260137703
2026-05-21

2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER

#3
20260116889
2026-04-30

MACROCYCLIC PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE DISEASE CONTAINING SAME AS ACTIVE INGREDIENT

#4
20260083744
2026-03-26

METHODS TO STRENGTHEN VISUAL PATHWAYS

#5
20260078379
2026-03-19

Use of a Janus Kinase Inhibitor and a Telomerase Inhibitor for the Treatment of Myeloproliferative Neoplasms

#6
20260070927
2026-03-12

INDAZOLE MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE

#7
20260049077
2026-02-19

Neurotrophic Receptor Tyrosine Kinase (NTRK) Inhibitors and Methods Using Same

#8
20260028352
2026-01-29

MACROCYCLIC IMIDAZO [1,2-B] PYRIDAZINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF

#9
20260014161
2026-01-15

Uses of JAK Inhibitors in the Management of Inflammation-Associated Depression and Central Nervous System (CNS) Pathologies

#10
20260008777
2026-01-08

INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE

#11
20250382303
2025-12-18

NOVEL COMPOUND AS NADPH OXIDASE 2 INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

#12
20250360136
2025-11-27

Treatment or Reversal of Treatment Resistant Depression and Related Central Nervous System (CNS) Inflammatory Conditions with a JAK Inhibitor

#13
20250345329
2025-11-13

HETEROARYL DERIVATIVE COMPOUND AND USES THEREOF

#14
20250340574
2025-11-06

MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

#15
20250340569
2025-11-06

INHIBITORS OF KIF18A AND USES THEREOF

#16
20250319111
2025-10-16

METHODS OF TREATING FLT3-MUTATED HEMATOLOGIC CANCERS

#17
20250319025
2025-10-16

COMPOSITIONS COMPRISING MODIFIED PHOSPHOLIPIDS AND USES THEREOF

#18
20250313575
2025-10-09

MACROCYCLES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF

#19
20250288683
2025-09-18

TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS

#20
20250282771
2025-09-11

TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS

#21
20250262216
2025-08-21

THERAPEUTIC USES OF MACROCYCLIC COMPOUNDS

#22
20250255870
2025-08-14

METHODS FOR TREATING HAIR LOSS AND NAIL BRITTLENESS, FRAGILITY, OR PITTING

#23
20250241862
2025-07-31

EXOSOMAL COMPOSITIONS INCLUDING ANESTHETICS

#24
20250221971
2025-07-10

METHODS OF TREATMENT FOR CYSTIC FIBROSIS

#25
20250197424
2025-06-19

QUINOLINE COMPOUND AND USE THEREOF

#26
20250188093
2025-06-12

TYK2 INHIBITORS AND USES THEREOF

#27
20250154153
2025-05-15

DIHYDROIMIDAZO-PYRIMIDINONE COMPOUNDS AS LP-PLA2 INHIBITORS AND USE THEREOF

#28
20250122218
2025-04-17

MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

#29
20250049711
2025-02-13

COMPOSITIONS COMPRISING MODIFIED PHOSPHOLIPIDS AND USES THEREOF

#30
20240398824
2024-12-05

Inhibition Of Rip Kinases For Treating Neurodegenerative Disorders

#31
20240390707
2024-11-28

METHODS FOR TREATING HAIR LOSS DISORDERS

#32
20240352021
2024-10-24

COVALENT EGFR INHIBITORS AND METHODS OF USE THEREOF

#33
20240343740
2024-10-17

MACROCYCLIC GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS

#34
20240317777
2024-09-26

NOVEL MACROCYCLIC AMINOPYRAZOLE COMPOUNDS AS CDK2 INHIBITORS

#35
20240254142
2024-08-01

POLYMORPHIC FORM OF TG02 FOR TREATING CANCER

#36
20240254141
2024-08-01

POLYMORPHIC FORM OF TG02 FOR TREATING CANCER

#37
20240228506
2024-07-11

RIPK1 INHIBITORS AND METHODS OF USE

#38
20240189315
2024-06-13

Cyclic Pyridine Derivatives as cGAS Inhibitors

#39
20240156824
2024-05-16

TREATMENT OF CANCER WITH TG02

#40
20240150377
2024-05-09

MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

#41
20240033330
2024-02-01

TYPE I DIABETES THERAPY

#42
20240001086
2024-01-04

SYSTEMS, DEVICES, AND METHODS FOR TREATING A PULMONARY DISORDER WITH AN AGENT

#43
20230382924
2023-11-30

MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

#44
20230374038
2023-11-23

MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

#45
20230248733
2023-08-10

HIGHLY ACTIVE ANTI-NEOPLASTIC AND ANTI-PROLIFERATIVE AGENTS

#46
20230167166
2023-06-01

TARGETED THERAPY FOR THE TREATMENT & PREVENTION OF LIFE-THREATENING COMPLICATIONS OF INFECTION

#47
20230139282
2023-05-04

ANTIMALARIAL AGENTS

#48
20230111697
2023-04-13

Methods for treating hair loss disorders

#49
20230099804
2023-03-30

MACROCYCLIC ULK1/2 INHIBITORS

#50
20230099745
2023-03-30

MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

#51
20230075851
2023-03-09

SYSTEMS, DEVICES, AND METHODS FOR TREATING A PULMONARY DISORDER WITH AN AGENT

#52
20230043374
2023-02-09

Methods for treating hair loss disorders

#53
20220313698
2022-10-06

MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

#54
20220125933
2022-04-28

LIPID PRODRUGS OF JAK INHIBITORS AND USES THEREOF

#55
20220047686
2022-02-17

METHODS FOR TREATING INFECTIOUS DISEASES

#56
20220008448
2022-01-13

METHODS OF TREATING FLT3-MUTATED HEMATOLOGIC CANCERS

#57
20210322427
2021-10-21

INHIBITION OF RIP KINASES FOR TREATING NEURODEGENERATIVE DISORDERS

#58
20210322396
2021-10-21

COMPOSITIONS WITH SYNERGISTIC PERMEATION ENHANCERS FOR DRUG DELIVERY

#59
20210269807
2021-09-02

USE OF A JANUS KINASE INHIBITOR AND A TELOMERASE INHIBITOR FOR THE TREATMENT OF MYELOPROLIFERATIVE NEOPLASMS

#60
20210252004
2021-08-19

Use of sodium channel blockers for the treatment of neuropathic pain developing as a consequence of chemotherapy

#61
20210213021
2021-07-15

TOPICAL COMPOSITIONS FOR STIMULATING HAIR GROWTH

#62
20210161997
2021-06-03

TREATING DISEASES VIA TARGETED MODULATION OF GENE SIGNALING NETWORKS

#63
20210069199
2021-03-11

METHODS OF TREATING TRANSPLANT REJECTION

#64
20210053988
2021-02-25

Substituted 1,4-methanopyrido[1′,2′:4,5]pyrazino[1,2-a]pyrimidines for treating viral infections

#65
20200405725
2020-12-31

Pyrazolopyrimidine derivative and use thereof

#66
20200345815
2020-11-05

Type I diabetes therapy

#67
20200345743
2020-11-05

HIGHLY ACTIVE ANTI-NEOPLASTIC AND ANTI-PROLIFERATIVE AGENTS

#68
20200323862
2020-10-15

Treatment of cancer with TG02

#69
20200262843
2020-08-20

Polymorphic form of TG02 for treating cancer

#70
20200237635
2020-07-30

Methods for treating hair loss disorders

#71
20190262250
2019-08-29

Methods for treating hair loss disorders

#72
20190160074
2019-05-30

Use of sodium channel blockers for the treatment of neuropathic pain developing as a consequence of chemotherapy

#73
20190151322
2019-05-23

Macrocyclic compounds as ROS1 kinase inhibitors

#74
20190125752
2019-05-02

Highly active anti-neoplastic and anti-proliferative agents

#75
20190092787
2019-03-28

Substituted 3,4,5,6,8,10,14,14a-octahydro-2h-2,6-methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazocines and methods for treating viral infections

#76
20190076437
2019-03-14

Macrocylic compounds as ROS1 kinase inhibitors

#77
20190076436
2019-03-14

MACROCYCLIC COMPOUNDS AS ROS1 KINASE INHIBITORS

#78
20190055263
2019-02-21

Polymorphic form of TG02

#79
20180318306
2018-11-08

METHODS OF TREATING TRANSPLANT REJECTION

#80
20180303839
2018-10-25

Methods and devices for renal nerve blocking

#81
20180289670
2018-10-11

COMBINATION OF LBH589 WITH OTHER THERAPEUTIC AGENTS FOR TREATING CANCER

#82
20180282346
2018-10-04

Modified macrocyclic compounds

#83
20180256586
2018-09-13

Compounds and methods for the targeted degradation of fetal liver kinase polypeptides

#84
20180207154
2018-07-26

Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor and/or a JAK-2 Inhibitor

#85
20180086761
2018-03-29

Heterocyclic compounds and their use in preventing or treating bacterial infections

#86
20180071251
2018-03-15

COMBINATION OF LBH589 WITH OTHER THERAPEUTIC AGENTS FOR TREATING CANCER

#87
20180021235
2018-01-25

Methods for treating hair loss disorders

#88
20180015096
2018-01-18

HIGHLY ACTIVE ANTI-NEOPLASTIC AND ANTI-PROLIFERATIVE AGENTS

#89
20170260204
2017-09-14

Substituted 2,3,4,5,7,9,13,13a-octahydro-1,5-methanopyrido[1′,2′:4,5]pyrazino[1,2-a][1,3]diazepines and methods for treating viral infections

#90
20170246147
2017-08-31

COMBINATION OF LBH589 WITH OTHER THERAPEUTIC AGENTS FOR TREATING CANCER

#91
20170136043
2017-05-18

Therapeutic uses of selected pyrrolopyrimidine compounds with anti-mer tyrosine kinase activity

#92
20170136014
2017-05-18

Therapeutic combinations of a BTK inhibitor, a PI3K inhibitor and/or a JAK-2 inhibitor

#93
20170112842
2017-04-27

Macrocyclic compounds as Trk kinase inhibitors

#94
20170065598
2017-03-09

Methods to treat visual impairment

#95
20170027948
2017-02-02

MACROCYCLIC COMPOUNDS AS ALK, FAK AND JAK2 INHIBITORS

#96
20170015681
2017-01-19

Imidazopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication

#97
20170000797
2017-01-05

Use of sodium channel blockers for the treatment of neuropathic pain developing as a consequence of chemotherapy

#98
20160256461
2016-09-08

Methods for treating hair loss disorders

#99
20160256374
2016-09-08

Methods for treating hair loss disorders

#100
20160221963
2016-08-04

Pyridazinone compounds and uses thereof

#101
20160095862
2016-04-07

Methods and devices for renal nerve blocking

#102
20160058765
2016-03-03

Methods for treating hair loss disorders

#103
20160058764
2016-03-03

Methods for treating hair loss disorders

#104
20160039844
2016-02-11

Inhibitors of human immunodeficiency virus replication

#105
20160002263
2016-01-07

Inhibitors of human immunodeficiency virus replication

#106
20150328201
2015-11-19

Nitrogen containing compounds

#107
20150174133
2015-06-25

Nitrogen containing compounds

#108
20150094274
2015-04-02

COMBINATION OF LBH589 WITH OTHER THERAPEUTIC AGENTS FOR TREATING CANCER

#109
20150005285
2015-01-01

Nitrogen containing compounds

#110
20140348803
2014-11-27

Compositions and methods for obtaining cells to treat heart tissue

#111
20140256746
2014-09-11

Methods for Treating Osteoarthritis

#112
20140221356
2014-08-07

Substituted 2,3,4,5,7,9,13,13a-octahydropyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazepines and methods for treating viral infections

#113
20140148431
2014-05-29

1,6-diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections

#114
20140113920
2014-04-24

Tricyclic heterocycles useful as dipeptidyl peptidase-IV inhibitors

#115
20130281389
2013-10-24

Drug targets to overcome de novo drug-resistance in multiple myeloma

#116
20130029927
2013-01-31

COMBINATION OF LBH589 WITH OTHER THERAPEUTIC AGENTS FOR TREATING CANCER

#117
20120301538
2012-11-29

PHARMACEUTICAL COMPOSITIONS FOR THE STIMULATION OF STEM CELLS

#118
20120277307
2012-11-01

Method for treating osteoarthritis

#119
20120264767
2012-10-18

Stable pharmaceutical composition of freeze-dried tetrodotoxin powder

#120
20120034296
2012-02-09

PROLONGED DURATION LOCAL ANESTHESIA WITH MINIMAL TOXICITY

#121
20110275581
2011-11-10

Nuclear export inhibitors of topoisomerase II alpha

#122
20110245214
2011-10-06

Organic compounds

#123
20110201627
2011-08-18

FREEZE-DRIED REPARATION OF TETRODOTOXIN AND THE PRODUCING METHOD THEREOF

#124
20110117065
2011-05-19

Compositions and methods for obtaining cells to treat heart tissue

#125
20110071104
2011-03-24

Methods for treating osteoarthritis

#126
20100249150
2010-09-30

Stable pharmaceutical composition of freeze-dried tetrodoxin powder

#127
20100215771
2010-08-26

Use of sodium channel blockers for the treatment of neuropathic pain developing as a consequence of chemotherapy

#128
20100069458
2010-03-18

COMBINATION OF LBH589 WITH OTHER THERAPEUTIC AGENTS FOR TREATING CANCER

#129
20100048592
2010-02-25

Use of sodium channel blockers for the management of musculoskeletal pain

#130
20090239850
2009-09-24

Kinase modulating compounds and uses thereof for treatment of cancer

#131
20080213331
2008-09-04

METHODS AND DEVICES FOR RENAL NERVE BLOCKING

#132
20060270716
2006-11-30

Method for treating osteoarthritis

#133
20060039930
2006-02-23

METHODS FOR ENHANCING WOUND HEALING

#134
20050282836
2005-12-22

Solid orally ingestible formulations of tetrodotoxin

#135
20050175637
2005-08-11

Methods for enhancing wound healing

#136
20050159337
2005-07-21

Use of botulinum toxin therapy for treatment of recalcitrant voiding dysfunction

#137
20050020610
2005-01-27

Stable pharmaceutical composition of freeze-dried tetrodotoxin powder