20537 ⎘
Medicinal preparations containing organic active ingredients; Carbohydrates; Sugars; Derivatives thereof; Compounds having three or more nucleosides or nucleotides Double-stranded nucleic acids or oligonucleotides
Inhibitors of prolyl-hydroxylase-1 for the treatment of skeletal muscle degeneration
#4802Novel cochleate formulations
#4803Cancer cell-specific apoptosis-inducing agents that target chromosome stabilization-associated genes
#4804Double-Stranded Oligonucleotides
#4805DECOY-OLIGNUCLEOTIDE INHIBITION OF CD40-EXPRESSION
#4806Complex Particles and Coated Complex Particles
#4807TREATMENT OF CANCER WITH ANTI-MUSCARINIC RECEPTOR AGENTS
#4808INTRANASAL DELIVERY OF NUCLEIC ACID MOLECULES
#4809Method of treatment of skin inflammation
#4810Pharmaceutical preparation with RNA as hemostasis cofactor
#4811Use of Sirnas in Organ Storage/Reperfusion Solutions
#4812siRNA targeting proprotein convertase subtilisin/kexin type 9 (PCSK9)
#4813Therapeutic Agents for the Treatment of Hmgb1-Related Pathologies
#4814siRNA targeting vascular endothelial growth factor receptor 1 (VEGFR1)
#4815Bacterially derived intact minicells that encompass plasmid free functional nucleic acid for in vivo delivery to mammalian cells
#4816siRNA targeting protein tyrosine phosphatase-1B (PTP1B)
#4817siRNA targeting casitas B cell lymphoma-B (CBL-B)
#4818Intranuclear protein transduction through a nucleoside salvage pathway
#4819Modulation of MUC1 activity
#4820Methods for bone treatment by modulating an arachidonic acid metabolic or signaling pathway
#4821SATB1: A DETERMINANT OF MORPHOGENESIS AND TUMOR METASTASIS
#4822METHOD AND COMPOSITION FOR TREATING CANCER
#4823Methods and compositions for modulating vascular integrity
#4824Lipids, lipid complexes and use thereof
#4825Compositions for silencing the expression of VDAC1 and uses thereof
#4826Bispecific antisense oligonucleotides that inhibit IGFBP-2 and IGFBP-5 and methods of using same
#4827METHODS AND COMPOSITIONS FOR ENHANCING DELIVERY OF DOUBLE-STRANDED RNA OR A DOUBLE-STRANDED HYBRID NUCLEIC ACID TO REGULATE GENE EXPRESSION IN MAMMALIAN CELLS
#4828Method and medicament for inhibiting the expression of a given gene
#4829Use of anti-mortalin 2 antibody and functional nucleic acid for cancer therapies
#4830Genetic inhibition of double-stranded RNA
#4831Inhibitor Nucleic Acids
#4832Method and medicament for inhibiting the expression of a given gene
#4833siRNA targeting ribonucleotide reductase M2 polypeptide (RRM2 or RNR-R2)
#4834siRNA targeting cystic fibrosis transmembrane conductance regulator (CFTR)
#4835Methods and compositions for reducing activity of the atrial natriuretic peptide receptor and for treatment of diseases
#4836METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER OR OTHER DISEASES
#4837RNA inteference mediated inhibition of hepatitis C virus (HVC) gene expression using short interfering nucleic acid (siNA)
#4838Methods and compositions to treat misfolded-SOD1 mediated diseases
#4839Highly Potent Hsirna Mixtures and Method for Gene Splicing
#4840siRNA targeting human hairless protein (HR)
#4841siRNA targeting DNA-damage-inducible transcript 4 (DDIT4)
#4842Method and medicament for inhibiting the expression of a given gene
#4843Methods and compositions for transdermal delivery of nucleotides
#4844siRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B)
#4845Methods and compositions involving miRNA and miRNA inhibitor molecules
#4846Method and medicament for inhibiting the expression of a given gene
#4847Method and medicament for inhibiting the expression of a given gene
#4848Methods and compositions involving miRNA and miRNA inhibitor molecules
#4849Stabilized immune modulatory RNA (SIMRA) compounds for TLR7 and TLR8
#4850Methods for Modulating the Efficacy of Nucleic Acid Based Therapies
#4851Method and medicament for inhibiting the expression of a given gene
#4852Methods of altering bone growth by administration of sost or wise antagonist or agonist
#4853Oligonucleotides for RNA interference and biological applications thereof
#4854Treatment of neurological disorders by dsRNA administration
#4855Efficient process for producing dumbbell DNA
#4856siRNA targeting myeloid cell leukemia sequence 1
#4857Functional and hyperfunctional siRNA directed against Bcl-2
#4858Compositions and methods for inhibiting expression of the PCSK9 gene
#4859Polynucleotides for causing RNA interference and method for inhibiting gene expression using the same
#4860Functional and hyperfunctional siRNA directed against Bcl-2
#4861Functional and hyperfunctional siRNA directed against Bcl-2
#4862Functional and hyperfunctional siRNA directed against Bcl-2
#4863Functional and hyperfunctional siRNA directed against Bcl-2
#4864Functional and hyperfunctional siRNA directed against Bcl-2
#4865Functional and hyperfunctional siRNA directed against Bcl-2
#4866Functional and hyperfunctional siRNA directed against Bcl-2
#4867Amphoteric liposomes, a method of formulating an amphoteric liposome and a method of loading an amphoteric liposome
#4868Genetic inhibition by double-stranded RNA
#4869Methods for inhibiting osteoclastic bone resorption and bone loss comprising administration of an anti-FSH or anti-FSHR antibody
#4870Methods and compositions involving miRNA and miRNA inhibitor molecules
#4871Genetic inhibition by double-stranded RNA
#4872Targeted delivery of drugs, therapeutic nucleic acids and functional nucleic acids to mammalian cells via intact killed bacterial cells
#4873Conductance of improperly folded proteins through the secretory pathway and related methods for treating disease
#4874Method for the treatment of neurological disorders by enhancing the activity of β-glucocerebrosidase
#4875Antisense modulation of kinesin-like 1 expression
#4876Delivering functional nucleic acids to mammalian cells via bacterially-derived, intact minicells
#4877Methods and compositions to treat and detect misfolded-SOD1 mediated diseases
#4878siRNA hat inhibits WT1 gene expression and uses thereof
#4879Cancer Associated Antigens
#4880RNAI-mediated inhibition of tumor necrosis factor α-related conditions
#4881Induction of Cellular Senescence by Cdk4 Disruption for Tumor Suppression and Regression
#4882Therapeutic compositions
#4883Nucleic acid-based compounds and methods of use thereof
#4884Multitargeting interfering RNAs having two active strands and methods for their design and use
#4885Methods of treating diabetes
#4886Identification and use of target genes for control of plant parasitic nematodes
#4887Individualized cancer therapy
#4888Apoptosis Inducer for Cancer Cell
#4889Polynucleotides for Reducing Respiratory Syncytial Virus Gene Expression
#4890Method and composition for treating and preventing tumor metastasis in vivo
#4891Methods for preventing and/or treating a cell proliferative disorder
#4892Small interfering RNA specific to sub-units α, α′and β of the Kinase Protein ck2, and the applications of the same
#4893siRNA silencing of influenza virus gene expression
#4894Pharmaceutical preparation with RNA as hemostasis cofactor
#4895Functional and hyperfunctional siRNA
#4896Muc1 Antagonist Enhancement of Death Receptor Ligand-Induced Apoptosis
#4897Compositions, devices and methods for treatment of huntington's disease through intracranial delivery of sirna
#4898RNAi-mediated inhibition of HIF1A for treatment of ocular angiogenesis
#4899Pharmaceutical composition
#4900Insulated herpesvirus-derived gene expression cassettes for sustained and regulatable gene expression
#4901siRNA targeting spleen tyrosine kinase
#4902Methods of using molecules related to organic cation transporter 3 (oct3) for treating depression, anxiety neuroses, drug dependencies, and other similar mental disorders
#4903Modified siRNA molecules and uses thereof
#4904Methods and compositions for the treatment of persistent infections
#4905Amphoteric liposomes
#4906siRNA targeting carbonic anhydrase II
#4907Method of evaluating inflammatory skin disorders using IL-17 and/or IL-19
#4908siRNA targeting MCL1
#4909Compositions and methods for diagnosing and treating cancers
#4910siRNA targeting tumor necrosis factor superfamily member 1A
#4911siRNA targeting complement factor B
#4912siRNA targeting BCL2L1
#4913siRNA targeting KRAS
#4914Gene therapy for regulating smooth muscle tone
#4915Polymer-based delivery system for immunotherapy of cancer
#4916siRNA targeting survivin
#4917Substituted, non-coding nucleic acid molecule for therapeutic and prophylactic stimulation of the immune system in humans and higher animals
#4918Oligonucleotide inhibiting the expression of star-binding protein (sbp) gene and method therefor
#4919Functional and hyperfunctional siRNA
#4920Functional and hyperfunctional siRNA
#4921Antibody against nox1 polypeptide, method of diagnosing cancer with the use of nox1 gene and method of screening cancer growth inhibitor
#4922Vectorization of dsRNA by cationic particles and use of same on a skin model
#4923Preparation for preventing contact of pathogenic matter with living organism
#4924Methods for treating parkinsons disease and parkinsonism
#4925Short interfering nucleic acid hybrids and methods thereof
#4926Decoy-oligonucleotide-inhibition of cd40-expression
#4927Methods and compositions for modulating vascular integrity
#4928Compositions and methods for treatment of prostate and other cancers
#4929Staple type oligonucleotide and drug comprising the same
#4930RNAi modulation of RSV and therapeutic uses thereof
#4931Sensitizing cells for apoptosis by selectively blocking cytokines
#4932Method and apparatus for treatment of cardiac disorders
#4933Methods for treating infectious disease exacerbated asthma
#4934RNAi-mediated inhibition of frizzled related protein-1 for treatment of glaucoma
#4935IRNA agents targeting VEGF
#4936Chemically modified double stranded nucleic acid molecules that mediate RNA interference
#4937Therapeutic uses of inhibitors of RTP801
#4938Methods and compositions to generate and control the effector profile of t cells by simultaneous loading and activation of selected subsets of antigen presenting cells
#4939Methods and sequences to suppress pro-inflamatory cytokine actions locally to treat pain
#4940Human liver regeneration associated protein and the use thereof
#4941Therapies for cancer using RLIP76
#4942Method for transporting a compound across the blood-brain barrier
#4943RNAi modulation of RSV and therapeutic uses thereof
#4944RNAi inhibition of CTGF for treatment of ocular disorders
#4945Induction of apoptosis in toll-like receptor expressing tumor cells
#4946RNA interference mediated inhibition of cyclin dependent kinase-2 (CDK2) gene expression using short interfering nucleic acid (siNA)
#4947Treatment of cancer by inhibition of IGFBP's and clusterin
#4948Methods and compositions for treating cellular proliferative diseases
#4949Diagnosis and treatment of cancers with microRNA located in or near cancer associated chromosomal features
#4950iRNA agents targeting VEGF
#4951Proteins, polynucleotides encoding them and methods of using the same
#4952Methods for the treatment of osteoarthritis and compositions thereof
#4953Chemically modified oligonucleotides
#4954Method to inhibit cell growth using oligonucleotides
#4955Administration of FGF2 for treamtent of anxiety
#4956Nanoparticles containing polymeric nucleic acid homologs
#4957Compositions and methods for treatment of prostate and other cancers
#4958Treatment of neurological disorders by dsrna administration
#4959Methods and compositions for enhancing delivery of double-stranded RNA or a double-stranded hybrid nucleic acid to regulate gene expression in mammalian cells
#4960Double-stranded oligonucleotides
#4961Means and methods for the specific modulation of target genes in the CNS and the eye and methods for their identification
#4962Modified L-nucleic acid
#4963Use of cytokine expression to predict skin inflammation; methods of treatment
#4964Combinatorial methods and compositions for treatment of melanoma
#4965Biodegradable poly(beta-amino esters) and uses thereof
#4966Intranasal delivery of nucleic acid molecules
#4967Dilation introducer for orthopedic surgery
#4968Inhibitor nucleic acids
#4969Methods and compositions for selecting siRNA of improved functionality
#4970Functional and hyperfunctional siRNA
#4971Functional and hyperfunctional siRNA directed against Bcl-2
#4972Means and methods for the specific inhibition of genes in cells and tissue of the cns and/or eye
#4973Compositions and methods to initiate or enhance antibody and major-histocompatibility class I or class II-restricted t cell responses by using immunomodulatory, non-coding rna motifs
#4974Therapeutic and diagnostic applications based on the role of the CXCR-4 gene in tumorigenesis
#4975Novel cochleate formulations
#4976Reducing arthritis and lameness in subjects by growth hormone releasing hormone (GHRH) supplementation
#4977Method and carrier complexes for delivering molecules to cells
#4978Pharmaceutical compositions containing angiogenic activators
#4979Nucleic acid-based compounds and methods of use thereof
#4980Compositions and methods for diagnosing and treating cancers
#4981Method and medicament for inhibiting the expression of a given gene
#4982Delivery of dsRNA to arthropods
#4983Pharmaceutical preparation with RNA as hemostasis cofactor
#4984Chimeric oligomeric compounds and their use in gene modulation
#4985System and method for delivering polynucleotides to the central nervous system
#4986Use of double-stranded ribonucleic acid for inducing cell lysis
#4987Modulation of insulin-regulated aminopeptidase (irap)/angiotensin iv (at4) receptor activity
#4988Xanthine dehydrogenase (XDH) iRNA compositions and methods of use thereof
#4989Nucleic acid-polypeptide compositions and methods of inducing exon skipping
#4990Nucleic acid-polypeptide compositions and uses thereof
#4991Biodegradable lipids for the delivery of active agents
#4992Conjugated antisense compounds and their use
#4993RNAs for complement inhibition
#4994Bacteria carrying bacteriophage and protease inhibitors for the treatment of disorders and methods of treatment
#4995LEMD3 antagonizes TGF-beta-driven Smad2/3 transcription in a stiffness-dependent fashion in both the nucleus and cytosol
#4996Modified RNA agents with reduced off-target effect
#4997Targeted nanoparticles
#4998Combination therapies for the treatment of Alzheimer's disease and related disorders
#4999High efficiency reprogramming of fibroblasts into cardiomyocytes
#5000Long noncoding RNAs and cell reprogramming and differentiation
#5001Bacteria carrying bacteriophage and protease inhibitors for the treatment of disorders and methods of treatment
#5002High efficiency reprogramming of fibroblasts into cardiomyocytes
#5003Multi-functional particles and methods of using the same
#5004Preventing tumor development and metastasis
#5005Long noncoding RNAs and cell reprogramming and differentiation
#5006Bacteria carrying bacteriophage and protease inhibitors for the treatment of disorders and methods of treatment
#5007Long noncoding RNAS and cell reprogramming and differentiation