ClassID:

21047

A61K38/52 - CPC Classification

Classification description:

Medicinal preparations containing peptides; Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof; Enzymes; Proenzymes; Derivatives thereof Isomerases (5)

Recent Application in this class:
#1
20260115266
2026-04-30

COMPOSITIONS COMPRISING PROTEIN DISULFIDE ISOMERASE AND METHODS OF PRODUCTION AND USE THEREOF

#2
20260115265
2026-04-30

METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING FOOD ALLERGIES

#3
20250228971
2025-07-17

DESIGN AND CONSTRUCTION OF EVOLUTIONARY-GUIDED "SELECTION GENE DRIVE" THERAPY

#4
20250177500
2025-06-05

SUCROSE ISOMERASES AS FOOD AND NUTRITIONAL SUPPLEMENTS

#5
20250144189
2025-05-08

ASPARAGINE RACEMASE AND USES THEREOF

#6
20250099384
2025-03-27

THIOESTER CATIONIC LIPIDS

#7
20240425839
2024-12-26

MODIFIED CASPASE-9 POLYPEPTIDES AND METHODS OF USE THEREOF

#8
20240424068
2024-12-26

USE OF LOW pH ACTIVE ALPHA-1,4;/1,6-GLYCOSIDE HYDROLASES (GLCH) AS A FEED ADDITIVE FOR RUMINANTS TO ENHANCE STARCH DIGESTION

#9
20240335517
2024-10-10

AGENT FOR USE IN THE CASE OF FRUCTOSE INTOLERANCE

#10
20240269248
2024-08-15

POLYNUCLEOTIDES ENCODING METHYLMALONYL-COA MUTASE FOR THE TREATMENT OF METHYLMALONIC ACIDEMIA

#11
20240238394
2024-07-18

COMPOSITIONS, SYSTEMS AND METHODS OF RNA EDITING USING DKC1

#12
20240226153
2024-07-11

COMPOSITIONS AND METHODS FOR SELECTIVE ELIMINATION AND REPLACEMENT OF HEMATOPOIETIC STEM CELLS

#13
20240226025
2024-07-11

POLYNUCLEOTIDES ENCODING METHYLMALONYL-COA MUTASE FOR THE TREATMENT OF METHYLMALONIC ACIDEMIA

#14
20240209341
2024-06-27

COMPOSITIONS AND METHODS FOR TARGETING INFLAMMATORY OR ACTIVATED CELLS AND TREATING OR AMELIORATING INFLAMMATORY CONDITIONS AND PAIN

#15
20240131067
2024-04-25

COMPOSITIONS AND METHODS FOR SELECTIVE ELIMINATION AND REPLACEMENT OF HEMATOPOIETIC STEM CELLS

#16
20240102001
2024-03-28

COUPLING ENDONUCLEASES WITH END-PROCESSING ENZYMES DRIVES HIGH EFFICIENCY GENE DISRUPTION

#17
20240075108
2024-03-07

HEPATOCELLULAR CARCINOMA TREATMENTS, PROPHYLACTIC THERAPIES, AND COMPOSITIONS FOR USE THEREWITH

#18
20240000969
2024-01-04

COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACIDS

#19
20230398195
2023-12-14

COMPOSITION DERIVED FROM MAMMALIAN UMBILICAL CORD AND WHARTONS JELLY FOR USE IN THERAPEUTIC AND REGENERATIVE APPLICATIONS

#20
20230321280
2023-10-12

COMPOSITIONS AND METHODS FOR THE TREATMENT OF OCULAR DISEASES

#21
20230270831
2023-08-31

METHODS FOR INDUCING SELECTIVE APOPTOSIS

#22
20230270685
2023-08-31

POLYNUCLEOTIDES ENCODING METHYLMALONYL-CoA MUTASE

#23
20230092238
2023-03-23

Tricine and Citric Acid Lipids

#24
20220305097
2022-09-29

METABOLIC THERAPY FOR OXIDATIVE STRESS IN THE BRAIN THROUGH TARGETED NEURONAL CATABOLISM OF N-ACETYL-ASPARTIC ACID

#25
20220235346
2022-07-28

Modified caspase-9 polypeptides and methods of use thereof

#26
20220142919
2022-05-12

DYNAMIC COVALENTLY LINKED HYDROGELS AS STABILIZATION NETWORK PLATFORMS

#27
20220125837
2022-04-28

METHODS FOR CONTROLLED ELIMINATION OF THERAPEUTIC CELLS

#28
20220106608
2022-04-07

FUSOGENIC LIPID NANOPARTICLES FOR THE TARGET CELL-SPECIFIC PRODUCTION OF RAPAMYCIN INDUCIBLE THERAPEUTIC PROTEINS

#29
20220088223
2022-03-24

METHODS AND COMPOSITIONS FOR INCREASING SIALIC ACID PRODUCTION AND TREATING SIALIC RELATED DISEASE CONDITIONS

#30
20220072111
2022-03-10

Agent for use in the case of fructose intolerance

#31
20220008338
2022-01-13

Thioester cationic lipids

#32
20210361753
2021-11-25

CYCLOPHILIN 40 FOR REDUCTION OF NEUROTOXIC FIBRILS AND TREATMENT OF NEURODEGENERATIVE DISEASES

#33
20210299229
2021-09-30

USE OF LOW pH ACTIVE ALPHA-1,4;/1,6-GLYCOSIDE HYDROLASES (GLCH) AS A FEED ADDITIVE FOR RUMINANTS TO ENHANCE STARCH DIGESTION

#34
20210261946
2021-08-26

Coupling endonucleases with end-processing enzymes drives high efficiency gene disruption

#35
20210254043
2021-08-19

Coupling endonucleases with end-processing enzymes drives high efficiency gene disruption

#36
20210220273
2021-07-22

Cationic lipids comprising a steroidal moiety

#37
20210196804
2021-07-01

SUCROSE ISOMERASES AS FOOD AND NUTRITIONAL SUPPLEMENTS

#38
20210130806
2021-05-06

ENGINEERED BACTERIA EXPRESSING RACEMASE FOR TREATING DISEASES ASSOCIATED WITH HYPERAMMONEMIA

#39
20200390906
2020-12-17

Compositions and methods for treating or ameliorating neuroinflammation, neurodegeneration, neuropathic pain, and migraine

#40
20200360494
2020-11-19

Method of making PDIA2 and compositions containing PDIA2

#41
20200338194
2020-10-29

CHIMERIC ANTIGEN RECEPTOR (CAR) SIGNALLING SYSTEM

#42
20200171134
2020-06-04

Metabolic therapy for oxidative stress in the brain through targeted neuronal catabolism of N-acetyl-aspartic acid

#43
20200171109
2020-06-04

Method for inducing production of vascular endothelial growth factor

#44
20200131498
2020-04-30

POLYNUCLEOTIDES ENCODING METHYLMALONYL-COA MUTASE

#45
20200078402
2020-03-12

Compositions and methods for selective elimination and replacement of hematopoietic stem cells

#46
20200078314
2020-03-12

Polynucleotides encoding methylmalonyl-CoA mutase

#47
20200030421
2020-01-30

METHODS FOR INDUCING SELECTIVE APOPTOSIS

#48
20190390203
2019-12-26

REDUCTION OF LIPASE ACTIVITY IN PRODUCT FORMULATIONS

#49
20190367945
2019-12-05

Method of treating type I diabetes using an AAV vector encoding uracortin 2

#50
20190365875
2019-12-05

Regulating chimeric antigen receptors

#51
20190358307
2019-11-28

THERAPEUTIC AGENT FOR CEREBRAL INFARCTION

#52
20190298814
2019-10-03

Synthetic methylmalonyl-CoA mutase transgene for the treatment of MUT class methylmalonic acidemia (MMA)

#53
20190290724
2019-09-26

COMPOSITIONS AND USES THEREOF

#54
20190282678
2019-09-19

Agent for use in the case of fructose intolerance

#55
20190224257
2019-07-25

Drug composition for angiogenesis therapy

#56
20190134167
2019-05-09

CYCLOPHILIN 40 FOR REDUCTION OF NEUROTOXIC FIBRILS AND TREATMENT OF NEURODEGENERATIVE DISEASES

#57
20190127721
2019-05-02

Modified caspase-9 polypeptides and methods of use thereof

#58
20190091300
2019-03-28

METHODS OF TREATING CANCER OF THE CENTRAL NERVOUS SYSTEM

#59
20180360993
2018-12-20

Compositions and methods for treating or ameliorating neuroinflammation, neurodegeneration, neuropathic pain, and migraine

#60
20180344818
2018-12-06

Agent for use in the case of fructose intolerance

#61
20180320165
2018-11-08

Coupling endonucleases with end-processing enzymes drives high efficiency gene disruption

#62
20180289838
2018-10-11

Polynucleotides encoding methylmalonyl-CoA mutase

#63
20180271961
2018-09-27

METHODS FOR INDUCING SELECTIVE APOPTOSIS

#64
20180271795
2018-09-27

Polynucleotides encoding methylmalonyl-CoA mutase

#65
20180251746
2018-09-06

MODIFIED CASPASE POLYPEPTIDES AND USES THEREOF

#66
20180243385
2018-08-30

Methods for inducing selective apoptosis

#67
20180179545
2018-06-28

Reduction of lipase activity in product formulations

#68
20180169197
2018-06-21

Agent for use in the case of fructose intolerance

#69
20180140687
2018-05-24

Metabolic therapy for oxidative stress in the brain through targeted neuronal catabolism of N-acetyl-aspartic acid

#70
20180087041
2018-03-29

TAGGED FORM OF MUT ENZYME, GENETIC CONSTRUCTS INCORPORATING IT, AND ITS USE IN GENE THEREAPY

#71
20180010148
2018-01-11

Method of treating type I diabetes using an AAV vector encoding uracortin 2

#72
20170326212
2017-11-16

Synthetic methylmalonyl-CoA mutase transgene for the treatment of MUT class methylmalonic acidemia (MMA)

#73
20170319668
2017-11-09

AGENT FOR USE IN THE CASE OF FRUCTOSE INTOLERANCE

#74
20170176417
2017-06-22

Method and pharmaceutical composition for use in the treatment of neurodegenerative disorders

#75
20170152505
2017-06-01

Coupling endonucleases with end-processing enzymes drives high efficiency gene disruption

#76
20170152504
2017-06-01

Coupling endonucleases with end-processing enzymes drives high efficiency gene disruption

#77
20170152503
2017-06-01

Coupling endonucleases with end-processing enzymes drives high efficiency gene disruption

#78
20170152502
2017-06-01

Coupling endonucleases with end-processing enzymes drives high efficiency gene disruption

#79
20170119829
2017-05-04

METHOD FOR INDUCING PRODUCTION OF VASCULAR ENDOTHELIAL GROWTH FACTOR

#80
20170056485
2017-03-02

CRYSTALLIZED XYLOSE ISOMERASE IN PREVENTION OF THE DEVELOPMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE

#81
20170042985
2017-02-16

METHODS OF USING CYCLOOXYGENASE-PROSTACYCLIN SYNTHASE FUSION GENE

#82
20170015987
2017-01-19

Modified Caspase polypeptides and uses thereof

#83
20170014508
2017-01-19

Chimeric antigen receptor (CAR) signalling system

#84
20160312226
2016-10-27

Reduction of lipase activity in product formulations

#85
20160312210
2016-10-27

Coupling endonucleases with end-processing enzymes drives high efficiency gene disruption

#86
20160311934
2016-10-27

HYDROXYALKYL STARCH DERIVATIVES AS REACTANTS FOR COUPLING TO THIOL GROUPS

#87
20160258966
2016-09-08

Compositions and Methods for Diagnosing and Treating Diseases and Disorders Associated With D-DT

#88
20160243207
2016-08-25

AGENT FOR USE IN THE CASE OF FRUCTOSE INTOLERANCE

#89
20160175404
2016-06-23

Agent for reducing the useable calorie content of food and for therapeutic reduction of weight, in particular for use in the case of adiposity (obesity)

#90
20160166613
2016-06-16

METHODS FOR CONTROLLED ELIMINATION OF THERAPEUTIC CELLS

#91
20160114005
2016-04-28

HYBRID PROTEIN THAT CONVERTS ARACHIDONIC ACID INTO PROSTACYCLIN

#92
20160090585
2016-03-31

ISOMERASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM

#93
20150366954
2015-12-24

Methods for inducing selective apoptosis

#94
20150328292
2015-11-19

CASPASE POLYPEPTIDES HAVING MODIFIED ACTIVITY AND USES THEREOF

#95
20150216949
2015-08-06

Methods of treating cancer of the central nervous system

#96
20150209262
2015-07-30

Composition for preventing hair loss or enhancing hair growth comprising cyclophilin A

#97
20150104437
2015-04-16

Methods for the treatment and diagnosis of bone mineral density related diseases

#98
20140377224
2014-12-25

Method of treating or retarding the development of blindness

#99
20140286924
2014-09-25

Agent for use in the case of disorders of blood sugar metabolism, including diabetes

#100
20140275230
2014-09-18

Methods and compositions for increasing sialic acid production and treating sialic related disease conditions

#101
20140030244
2014-01-30

EXTRACTS ISOLATED FROM ELECTROPORATED AMBHIBIAN OOCYTES AND USE THEREOF IN TREATING DISEASES AND DISORDERS

#102
20140010791
2014-01-09

Methods for regulating protein function in cells in vivo using synthetic small molecules

#103
20130336950
2013-12-19

MATERIAL COMBINATION FOR TREATING INFLAMMATORY OR INFECTIOUS DISEASES

#104
20130330368
2013-12-12

Eye drop composition for prevention and treatment of ophthalmic diseases containing fusion protein of FK506 binding protein

#105
20130323229
2013-12-05

Metabolic therapy for oxidative stress in the brain through targeted neuronal catabolism of N-acetyl-aspartic acid

#106
20130302411
2013-11-14

Agent for use in the case of fructose intolerance

#107
20130224171
2013-08-29

Agent for use in the case of fructose intolerance

#108
20130216500
2013-08-22

METHOD OF TREATING OR RETARDING THE DEVELOPMENT OF BLINDNESS

#109
20130209488
2013-08-15

Methods and compositions for malic enzyme 2 (ME2) as a target for cancer therapy

#110
20130202696
2013-08-08

Agent for use in the case of fructose intolerance

#111
20130202695
2013-08-08

Agent for use in the case of fructose intolerance

#112
20130202694
2013-08-08

Agent for use in the case of fructose intolerance

#113
20130123188
2013-05-16

Methods for diagnosing and treating alzheimer's disease (AD) using the molecules that stabilize intracellular calcium (Ca) release

#114
20130030040
2013-01-31

METHODS AND COMPOSITIONS FOR INCREASING SIALIC ACID PRODUCTION AND TREATING SIALIC RELATED DISEASE CONDITIONS

#115
20120276074
2012-11-01

Coupling endonucleases with end-processing enzymes drives high efficiency gene disruption

#116
20120225930
2012-09-06

METHOD OF TREATING OR RETARDING THE DEVELOPMENT OF BLINDNESS

#117
20120156221
2012-06-21

Method and Pharmaceutical Composition for Use in the Treatment of Neurodegenerative Disorders

#118
20120156170
2012-06-21

DRUG COMPOSITION FOR ANGIOGENESIS THERAPY

#119
20110318308
2011-12-29

LIPOCALIN-TYPE PROSTAGLANDIN D2 SYNTHASE AS A BIOMARKER FOR LUNG CANCER PROGRESSION AND PROGNOSIS

#120
20110286980
2011-11-24

Methods for inducing selective apoptosis

#121
20110165231
2011-07-07

Treatment of fructose malabsorption

#122
20110151006
2011-06-23

STIMULI-RESPONSIVE HYDROGEL

#123
20110070218
2011-03-24

Methods of treating cancer of the central nervous system

#124
20110053245
2011-03-03

Isomerases, nucleic acids encoding them and methods for making and using them

#125
20100284991
2010-11-11

Methods for the Treatment and Diagnosis of Bone Mineral Density Related Diseases

#126
20100272688
2010-10-28

Method of treating or retarding the development of blindness

#127
20100240735
2010-09-23

Compositions and methods for angiogenic therapy utilizing genes encoding ets-1

#128
20100168209
2010-07-01

Apoptosis inducer for cancer cell

#129
20100034777
2010-02-11

Method for regulating protein function in cells in vivo using synthetic small molecules

#130
20100016224
2010-01-21

COMPOSITIONS AND METHODS FOR MODULATING AN IMMUNE RESPONSE

#131
20100015120
2010-01-21

HYBRID PROTEIN THAT CONVERTS ARACHIDONIC ACID INTO PROSTACYCLIN

#132
20090311232
2009-12-17

Agent for use in the case of fructose intolerance

#133
20090298771
2009-12-03

USE OF SECRETED PROTEIN PRODUCTS FOR PREVENTING AND TREATING PANCREATIC DISEASES AND/OR OBESITY AND/OR METABOLIC SYNDROME

#134
20090258794
2009-10-15

APOPTOSIS METHODS, GENES AND PROTEINS

#135
20090214620
2009-08-27

AGENT FOR USE IN THE CASE OF DISORDERS OF BLOOD SUGAR METABOLISM, INCLUDING DIABETES

#136
20090081300
2009-03-26

AGENT FOR USE IN THE CASE OF FRUCTOSE INTOLERANCE

#137
20090074723
2009-03-19

Method of Treating or Retarding the Development of Blindness

#138
20090060956
2009-03-05

AGENT FOR REDUCING THE USEABLE CALORIE CONTENT OF FOOD AND FOR THERAPEUTIC REDUCTION OF WEIGHT, IN PARTICULAR FOR USE IN THE CASE OF ADIPOSITY (OBESITY)

#139
20090053209
2009-02-26

Blockade of Pin1 Prevents Cytokine Production by Activated Immune Cells

#140
20090010911
2009-01-08

METHODS AND COMPOSITIONS FOR AFFECTING CYCLOPHILIN A REGULATION OF KINASES IN MODULATING CELLULAR ACTIVITIES

#141
20090004172
2009-01-01

SERVICE FOR EFFECTING LOCALIZED, NON-SYSTEMIC AND SYSTEMIC, IMMUNOGENIC TREATMENT OF CANCER USING ERP57 TRANSLOCATION

#142
20080279821
2008-11-13

ARYLPIPERIDINYL AND ARYLPYRROLIDINYL MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS

#143
20080233099
2008-09-25

Method and composition for protecting neuronal tissue from damage induced by elevated glutamate levels

#144
20080233096
2008-09-25

Method and composition for protecting neuronal tissue from damage induced by elevated glutamate levels

#145
20080182777
2008-07-31

Regulation of cell migration and adhesion

#146
20080181875
2008-07-31

USE OF CYCLOPHILIN AS ANTIOXIDANT AND PREVENTION OF CYCLOSPORIN A-INDUCED TOXICITY IN CELL TRANSPLANTATION BY OVEREXPRESSION OF CYCLOPHILIN

#147
20080145340
2008-06-19

Neuroactive agents and methods of their use

#148
20080075713
2008-03-27

Protein Disulfide Isomerase and ABC Transporter Homologous Proteins Involved in the Regulation of Energy Homeostasis

#149
20070281885
2007-12-06

Macrocylic oximyl hepatitis C protease inhibitors

#150
20070248607
2007-10-25

NEGATIVE IMMUNOMODULATION OF IMMUNE RESPONSES BY NKG2D-POSITIVE CD4+ CELLS

#151
20070248579
2007-10-25

Use of Secreted Protein Products for Preventing and Treating Pancreatic Diseases and/or Obesity and/or Metabolic Syndrome

#152
20070243570
2007-10-18

Apoptosis Inducer for Cancer Cell

#153
20070185048
2007-08-09

Protein disulfide isomerase and ABC transporter homologous proteins involved in the regulation of energy homeostasis

#154
20070077228
2007-04-05

Method of treating or retarding the development of blindness

#155
20070032423
2007-02-08

Methods and compositions for modulating somatolactogenic functions

#156
20060264359
2006-11-23

Blockade of Pin1 prevents cytokine production by activated immune cells

#157
20060052326
2006-03-09

Werner's syndrome helicase as a target for anti -HIV/AIDS therapy

#158
20060024284
2006-02-02

Method and composition for protecting neuronal tissue from damage induced by elevated glutamate levels

#159
20060024234
2006-02-02

Protein markers for pharmaceuticals and related toxicity

#160
20050282740
2005-12-22

Methods and compositions for regulating protein-protein interactions

#161
20050147601
2005-07-07

Regulation of cell migration and adhesion

#162
20050096273
2005-05-05

Regulation of matrix metalloproteinases by PSP94 family members

#163
20050074438
2005-04-07

Use of cyclophilin as antioxidant and prevention of cyclosporin a-induced toxicity in cell transplantation by overexpression of cyclophilin