CALCILYTIC COMPOUNDS

Use of tetrahydropyridines in the treatment of central nervous system disorders

Processes and intermediates for preparing steric compounds

Organocatalysts and methods of use in chemical synthesis

Cyclopropanes with central nervous system activity

Carboxylic Derivatives

Asymmetric hydrogenation of acyl enamides

Method for producing enantiomeric form of 2,3-diaminopropionic acid derivatives

Methamphetamine-like hapten compounds, linkers, carriers and compositions and uses thereof

Hydride reduction process for preparing quinolone intermediates

Tropane prodrugs with central nervous system activity

Process for Producing Optically Active Alcohol

Method for the production of optically active 3-alkylcarboxylic acids and the intermediate products thereof

Process for the diastereoselective alkylation of an ether oxime of the compound nopinone and novel intermediates for the synthesis of diastereospecific 2-amino-nopinone derivatives substituted on carbon 3

Zn-chelating motif-tethered short-chain fatty acids as a novel class of histone deacetylase inhibitors

Levodopa prodrug mesylate, compositions thereof, and uses thereof

Deuterated hepatitis C protease inhibitors

Method for producing asymmetric alkyl compound using alkali-treated solid support, and alkali-treated solid support used in this method

(R)-Chiral Halogenated Substituted Fused Heterocyclic Amino Compounds Useful for Inhibiting Cholesterol Ester Transfer Protein Activity

Stereoselective method for the production of Clopidogrel

Process for the hydrogenation of imines

Process for the enantiomeric enrichment of cis-8-benzyl-7,9-dioxo-2,8-diazabicyclo[4.3.0]nonane

Crystalline forms of (-)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol hydrochloride

Method and apparatus for conducting microwave assisted organic reactions with gas-phase reactants

Process for preparation of nonnatural amino acid and intermediate thereof

Process for preparation of optically active 1-erythro-2-amino-1-phenyl-1-propanol

Propargylated aminoindans, processes for preparation, and uses thereof

Methods for preparing sulfonamide substituted alcohols and intermediates thereof

Method of preparing optically pure phenethylamine derivatives

Asymmetric synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid

Selective N-sulfonylation of 2-amino fluoro- and trifluoroalkyl substituted alcohols

Method for the production of chiral secondary alcohols

Method for producing optically active carbonyl compounds

Chiral 3-carbamoylmethyl-5-methyl hexanoic acids, key intermediates for the synthesis of (S)-Pregabalin

Process for producing optically active fluorochemical

Multicyclic amino acid derivatives and methods of their use

Method for the separation of intermediates which may be used for the preparation of escitalopram

Chemical process for the preparation of intermediates to obtain -formyl hydroxy-lamine compounds

Processes and intermediates for the preparations of prostaglandins

Preparation of 2-(2-arylmorpholin-2-yl) ethanol derivatives and intermediates

Angiogenesis inhibitors and pharmaceutical/cosmetic applications thereof

Method of enantioselective nucleophilic addition reaction of enamide to imine and synthesis method of α-amino-γ-keto acid ester

Method of optically resolving racemic alcohols with a bicyclooxaoctane or a bicycooxaoctene resolving reagents

Chiral diphosphorus compounds and their transition metal complexes

SUBSTITUTED ARYLOXYPROPYLAMINES WITH SEROTONINERGIC AND/OR NOREPINEPHRINERGIC ACTIVITY

Carbonates of fenicol antibiotics

Diamine derivatives as inhibitors of leukotriene Ahydrolase

Optically active transition metal-diamine compound and process for producing optically active alcohol with the same

Process for preparing enantiomerically enriched 2-alkoxy-3-phenylpropionic acids

Process for chlorinating tertiary alcohols

Optically active 1-(fluoro-, trifluoromethyl- or trifluoromethoxy- substituted phenyl)alkylamine N-monoalkyl derivatives and process for producing same

Ferrocenyl-1,2-diphosphines, the production thereof and their use

Hydrogenation method for producing optically active alcohols or carboxylic acids

Asymmetric reductive amination of keto acid derivatives for producing amino acid derivatives

Method for producing optically active alcohols or carboxylic acids

Process for selective synthesis of enantiomers of substituted 1-(2-amino-1-phenyl-ethyl)-cyclohexanols

Method for the separation of intermediates which may be used for the preparation of escitalopram

Amino acids with affinity for the α2δ-protein

Production method of aminochlorohydrin sulfate

Process for preparing simvastatin and intermediates thereof

Process for the preparation of aminoalcohol derivatives and their further conversion to (1R, 4S)-4(2-amino-6-chloro-5-formamido-4-pyrimidinyl)-amino-2-cyclopentenyl-1-methanol

PROCESS FOR PREPARING SIMVASTATIN

Intermediates for the production of optically active cyclopropylamine derivatives and process for the production of the intermediates

Method for producing chiral mercapto amino acids

Process for the synthesis of (2S)-indoline-2-carboxylic acid

-C,D analogs of 1α,25-dihydroxy-19-norvitamin D

1-Amino-alkylcyclohexanes as 5-HT3 and neuronal nicotinic receptor antagonists

Method for producing optically active bisamidoalcohol compound

Peptidomimetic ligands for cellular receptors and ion channels

Enzyme-catalyzed dynamic kinetic resolution process for preparing (+)-(2s,3s)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinoland salts and solvates thereof

Synthesis of phenoxyacetic acid derivatives

Asymmetric carbon-carbon-bond-forming reactions catalyzed by bifunctional cinchona alkaloids

Process for the preparation of (s)-or (r)-4-halo-3-hydroxybutyrates

Method of enantioselective nucleophilic addition reaction of enamide to carbonyl group and synthesis method of optically active α-hydroxy-γ-keto acid ester and hydroxydiketone

Antitumor agents

Phosphines, transition metal complexes containing the same as the ligand, and process for production of optically active carboxylic acids

Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof

Method of manufacturing glimepiride and the respective intermediate

Aspirin-triggered lipid mediators

Process for preparing Cinacalcet hydrochloride

Method for the synthesis of 4-hydroxyisoleucine and the derivatives thereof

Synthetic techniques and intermediates for polyhydroxy dienyl lactones and mimics thereof

Novel compounds

Glutamate aggrecanase inhibitors

Novel compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them

Method for producing an optically active nitro compound

Polyethylene glycol esters of r-(+)-mcpp acid

Process for producing optically active 2-alkycysteine, derivative thereof, and processes for production

Process for the preparation of 1-(2,2,6-trimethylcyclohexyl)-hexan-3-ol

Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same

Alpha 2 delta ligands for post-traumatic stress disorder

Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use

Method of preparation of optically active alcohols

Phospholane salts and their use in enantioselective hydrogenation

NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS

Enantioselective synthesis of enantiomerically enriched compounds

Optically active 3,3'-dithiobis(2-amino-2methylpropionic acid) derivative and process for producing optically active 2-amino-3-mercapto-2-methylpropionic acid derivative

Stereospecific enrichment of heterocyclic enantiomers

Phospinite-imidazolines and metal complexes thereof

Process for the production of a hydroxyalkyne by coupling reaction between acetaldehyde and a terminal alkyne

Method of preparation of an alkyne with an optically active hydroxyl group in the beta or gamma position of a triple bond and intermediates obtained

Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids

Optically active α-aminooxyketone derivatives and process for production thereof

Catalytic asymmetric desymmetrization of prochiral and meso compounds

Method of preparing amine stereoisomers

2-alkylcysteinamide or salt thereof, process for producing these, and use of these

Compounds to treat alzheimer's disease

Process for producing optically active 1-alkyl-substituted 2,2,2-trifluoroethylamine

Synthesis of 2-alkylcysteine via phase transfer catalysis

Hydrogen succinate salts of trans-4-((1R, 3S)-6-chloro-3-phenylindan-1-YL)-1,2,2-trimethylpiperazine and the use as a medicament

-1(6-chloro-3-phenylindan-1-yl)-3,3-dimethylpiperazine

Compounds to treat Alzheimer's disease

Process for producing optically active dihydropyridinephosphonic ester

Analogs of discodermolide and dictyostatin-1, intermediates therefor and methods of synthesis thereof

Compounds, pharmaceutical compositions and methods for their use in treating metabolic disorders

Process for preparing 4-chloro-3-hydroxybutanoic acid ester

Process for the preparation of cyclopropyl carboxylic acid esters and derivatives

Carboxylic derivates

Ppar modulators

Process for the preparation of optically active cyclohexenones

Process for the preparation of aromatic amines

Interleukin-1 and tumor necrosis factor-α modulators, synthesis of said modulators and their enantiomers and methods of using said modulators

Process for the production of optically active compounds having substituents at the 2-position

Chiral arylketones in the treatment of neutrophil-dependent inflammatory diseases

Non-imidazole alkylamines as histamine H- receptor ligands and their therapeutic applications

Process for the preparation of and crystalline forms of optical enantiomers of modafinil

Efficient and economic asymmetric synthesis of nootkatone, tetrahydronootkatone, their precursors and derivatives

Long-chain, straight-chain 2-amino-3-hydroxyalkanes

Substituted paracyclophane derivatives in asymmetric catalysis

(R)-chiral halogenated substituted fused heterocyclic amino compounds useful for inhibiting cholesterol ester transfer protein activity

Compounds and compositions for use in the prevention and treatment of obesity and related syndromes

Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity

Process for resolving aimines that are useful for the treatment of disorders associated with insulin resistance syndrome

Optically active 2-allylcarboxylic acid derivative and process for producing the same

Synthesis of substituted thiazoline carboxylic acids

Amino alcohol ligand and its use in preparation of chiral proparglic tertiary alcohols and tertiary amines via enantioselective addition reaction

Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine

Process for the isomerisation of a cyclohexenyl alkyl or alkenyl ketone

Method for producing optically active carboxylic acid

Optically active copper catalyst composition

Method for preparing enantiomerically pure 4-pyrrolidino phenylbenzyl ether derivatives

Process for the preparation of aminoalcohol derivatives and their further conversion to (1R, 4S)-4(2-amino-6-chloro-5-formamido-4- pyrimidinyl)-amino-2-cyclopentenyl-1-methanol

Process for producing enantiopure β-amino acid derivatives, and enantiopure β-amino acid derivatives

Methods for detecting vasculopathies and tumors

2-oxabicyclo[3.3.0]octane compounds, process for producing the same, optical resolver, method of separating diastereomer mixture, and method of optically resolving alcohol

Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation

Process for enantioselective synthesis of single enantiomers of thio-substituted arylmethanesulfinyl derivatives by asymmetric oxidation

Process for the synthesis of enantiomeric indanylamine derivatives

Process for producing an alcohol or a silyl ether thereof

Methods of using derivatives of (-)-venlafaxine

Salts of (-)-O-desmethylvenlafaxine

Analogs of 4-hydroxyisoleucine and uses thereof

Enantioselective amination and etherification

Process for the preparation of optically pure isomers of 2-(4-hydroxy phenoxy)-2-methyl-butyric acid methyl ester

Pharmaceutically useful salts of carboxylic acid derivates

Method for making 2-(7-chloro-1,8-naphthyridine-2-yl)-3-(5-methyl-2-oxo-hexyl)-1-isoindolinone)

Enantioselective alpha-fluorination of aldehydes using chiral organic catalysts

Methods for the synthesis of astaxanthin

Method of hydroaminating N-alkenoylcarbamates with primary aromatic amines

Chiral monophosphorus compounds

Method for the synthesis of s-indoline-2-carboxylic acid and application thereof in the synthesis of perindopril

Compositions and methods comprising long-chain, straight-chain 2-amino-3-hydroxyalkanes

Methods of the treatment or prevention of exercise-induced asthma using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione

Method for the synthesis of astaxanthin

Methods for the synthesis of chiral dihydroxy intermediates useful for the chiral synthesis of carotenoids

Muscarinic agonists

3-Amino-3-arylpropionic acid n-alkyl esters, process for production thereof, and process for production of optically active 3-amino-3-arylpropionic acids and esters of the antipodes thereto

Process for the preparation of enantiomerically pure (r) or (s)-5-(2-aminopropyl)-2-methoxybenzenesulfonamide

Binaphthol derivatives and their use in optical resolution or optical transformation

New 3-aryl propionic acid derivatives and analogs

Method for producing menthol

Methods for the synthesis of unsaturated ketone intermediates useful for the synthesis of carotenoids

Process for the dehydration of substituted 4-dimethylamino-2-aryl-butan-2-ol compounds and process for the preparation of substituted dimethyl-(3-aryl-butyl)- amine compounds by heterogeneous catalysis

Process for producing optically active β-hydroxy-α-aminocarboxylic acid derivative

Process for preparing enantiomerically enriched 2-fluorocarboxylic esters

Propanolamine derivatives, process for preparation of 3-n-methylamino-1-(2-thienyl)-1-propanols and process for preparation of propanolamine derivatives

Synthesis of 2-alkyl amino acids

Method for producing a 3,5-dihydroxy-6-heptenoate

Isotopically labelly indlinone derivatives and process for their preparation

Compositions and methods for sterol isolation and purification

Hydride reduction of α,β-unsaturated carbonyl compounds using chiral organic catalysts

Asymmetric urea compound and process for producing asymmetric compound by asymmetric conjugate addition reaction with the same as catalyst

Adamantane derivatives, processes for their preparation and pharmaceutical composition containing them

Methods for making(-)-menthol and oxygenated menthane compounds

Methods for the synthesis of lutein

Optically active halohydrin derivative and process for producing optically active epoxy alcohol derivative from the same

Process for preparing optically active cyclic amines

Optically active bisoxazoline compounds, process for production of the same and use thereof

Preparation of 2-(2-arylmorpholin-2-yl) ethanol derivatives and intermediates

Transition metal complex and process for producing optically active alcohol

Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases

Synthesis of 2-alkyl amino acids

Pharmaceutically useful salts of carboxylic acid derivatives

5-HT7 receptor antagonists

Process for the preparation of chiral 8-(-3-aminopiperidin-1-yl) xanthines

Process for producing muscone and its intermediate

Process for producing (2R)-2-propyloctanoic acid and intermediate therefor

Method for the production of crystalline forms and crystalline forms of optical enantiomers of modafinil

Nitrogen-containing ligands

Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine and its formamide

Methods of preparing sulfinamides and sulfoxides

2-heptylcyclopropyl-1-carboxylic acid

Preparation of optically active amines

Method for producing an optically active β-amino acid

Method of production of (−)-(S)-3-[1-(dimethylamino)ethyl]phenyl-N-ethyl-N-methylcarbamate

Method for the production of optically active 2-amino 2-chloro, 2 hydroxy or 2-alkoxy-1-alcohols

Methods for the synthesis of chiral dihydroxy ketone intermediates useful for the chiral synthesis of carotenoids

Synthesis, characterization and biological action of optically active isomers of floxacins

Production process of gamma-cyhalothrin

Method for preparing L-iditol

Transition metal complex having diphosphine compound as ligand

Estrogen receptor modulators

Method of producing ethyl (3R, 5S, 6E)-7-[2 cyclopropyl-4-(fluorophenyl) quinoline-3-yl]-3, 5-dihydroxy-6-heptenoate

Methods for the synthesis of zeazanthin

Methods for the synthesis of astaxanthin

Enantioselective, catalytic allylation of ketones and olefins

Process for the resolution of racemic (R,S) -5-(2-(2-(2- ethoxyphenoxy) ethylamino)Propyl)-2-methoxybenzene sulfonamide (tamsulosin), its novel R and S isomers and their salts and processes for their preparation

Method of separating optically active dihydroxy-heptenoic acid esters

New process

Diazaphospholane ligands for asymmetric catalysis

Synthesis of chiral 2-alkyl amino acids

Process for producing optically active alpha-substituted cysteine or salt thereof, intermediate therefor, and process for producing the same

Process of preparing O-carbamoyl compounds in the presence of active amine group

Processes for the recovery of optically active diacyltartaric acids

Intermediates of bupropion metabolites synthesis

Synthesis of alpha fluoroalkyl amines

Process for producing l-alpha-methylcysteine derivative

Antibacterial agents

Enantioselective biotransformation for preparation of protein tyrosine kinase inhibitor intermediates

Acid and ester compounds and methods of using the same

Syntheses of quinazolinones

Process for α,β-dihydroxyalkenes and derivatives

Chiral diols, their manufacture and ligands and catalysts derived therefrom

Diastereoselective reductive amination process

Methods of making and using N-desmethylzopiclone

Analogs of dictyostatin, intermediates therefor and methods of synthesis thereof

Process for preparing enantiomerically pure 1,1′-spirobiindane-6,6′-diol derivatives

Aryloxyalkylamine NK-1/SSRI inhibitors

Synthesis of beta-elemene, intermediates thereto, analogues and uses thereof

Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine and its formamide

Asymmetric Michael and Aldol additions using bifunctional cinchona-alkaloid-based catalysts

Optically enhanced chiral ionic liquids

Process for producing benzoxazine derivative and production intermediate thereof

Isolated atomoxetine impurity, processes for the preparation of atomoxetine impurities and their use as reference standards

Processes for the preparation of tomoxetine

Process for the optical resolution and recycling of tomoxetine

Process and intermediates for preparing escitalopram

Enantiomerically pure atomoxetine and tomoxetine mandelate

Process for the preparation of atomoxetine hydrochloride

Method for producing lysine derivative

Diterpenoid compounds imparting stress resistance to plants

Reagents for asymmetric allylation, aldol, and tandem aldol and allyation reactions

Chiral diphosphorus compounds and transition metal complexes thereof

Process for the synthesis of intermediates useful for the synthesis of tubulin inhibitors

Process for preparing optically pure active compounds

Methods for making 2-(7-chloro-1,8-naphthyridine-2-yl)-3-(5-methyl-2oxo-hexyl)-1-isoidolinone

Bistropylidenediamines and use thereof

Diamines as modulators of chemokine receptor activity

Therapeutic agents

Process for producing optically active β-amino alcohol

Monophosphine compound, transition metal complex thereof and production method of optically active compound using the complex as asymmetric catalyst

Process for producing 3-hydroxycyclohexanone

Chiral diphosphinoterpenes and transition metal complexes thereof

2-amino- and 2-thio- substituted 1,3-diaminopropanes

Methods of using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4 acetylaminoisoindoline 1,3-dione

Process for preparing (r)-aryloxypropionic acid ester derivatives

Process for the synthesis of (1S)-4,5-dimethoxy-1-(methylaminomethyl)-benzocyclobutane and addition salts thereof, and to the application thereof in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

Chiral catalyst, process for preparing the same and its use in the oxidate coupling of naphthols

Chiral C2-symmetric biphenyls, their preparation and also metal complexes in which these ligands are present and their use as catalysts in chirogenic syntheses

Intermediates useful in the synthesis of HIV-protease inhibitors and methods for preparing the same

Novel sulfonic acid derivatives

Antitumor agents

Process for producing optically active 2-substituted carboxylic acid

Process for preparing R-(-)carnitine from S-(-)-chlorosuccinic acid or from a derivative thereof

Process for stereoselectively reducing 4-aryl-4-oxobutanoic acid derivatives

Method for the production of (s)-3-methylamino-1-(thien-2-yl)propan-1-ol

Catalytic hydrogenation processes

Process for the preparation of substituted tetralin and substituted indane derivatives

Pharmaceutical salts of 3-O-(3',3'-dimethylsuccinyl) betulinic acid

Supported ruthenium nanoparticle catalyst for cis -dihydroxylation and oxidative cleavage of alkenes

Ligand antagonists of RAR receptors and pharmaceutical/cosmetic applications thereof

Process for producing (4E)-5-chloro-2-isopropyl-4-pentenoate and optically active form thereof

Process for making chiral 1,4-disubstituted piperazines

Process for preparing secondary alcohol

Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation

Process for producing trans-4-amino-1-cyclohexanecarboxilic acid derivative

α-(Trifluoromethyl-substituted aryloxy, arylamino, arylthio or arylmethyl)-trifluoromethyl-substituted phenylacetic acids and derivatives as antidiabetic agents

Process for producing optically active nitroalcohols

Process for the preparation of enantiomerically enriched compounds

Cyclic ketones, their preparation and their use in the synthesis of amino acids

New process

Serine protease inhibitors

Stereoselective synthesis of certain trifluoromethyl-substituted alcohols

Process for hydrogenating unactivated imines using ruthenium complexes as catalysts

Main-group metal-based asymmetric catalysts and applications thereof

Synthesis of a 4-methylthiazole-4(S)-carboxylic acid compound

Process for the asymmetric epoxidation of olefins

Glucagon antagonists/inverse agonists

Compounds and methods for treatment of cancer and modulation of programmed cell death for melanoma and other cancer cells

Process for the synthesis of 1,3-diols