ClassID:

94298

C07D217/14 - CPC Classification

Classification description:

Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Sub-classes:
Recent Application in this class:
#1
20260130925
2026-05-14

METHODS FOR TREATING CANCER

#2
20250382271
2025-12-18

SODIUM-HYDROGEN EXCHANGER 3 INHIBITOR COMPOUNDS

#3
20250376443
2025-12-11

MASP-2 INHIBITORS AND METHODS OF USE

#4
20250368604
2025-12-04

MASP-2 INHIBITORS AND METHODS OF USE

#5
20250367188
2025-12-04

COMPOUNDS AND METHODS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS

#6
20250129020
2025-04-24

MASP-2 INHIBITORS AND METHODS OF USE

#7
20240366590
2024-11-07

COMPOUNDS AND METHODS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS

#8
20240092739
2024-03-21

COMPOUNDS AND METHODS OF USE

#9
20230150981
2023-05-18

N-HETEROARYLALKYL-2-(HETEROCYCLYL AND HETEROCYCLYLMETHYL) ACETAMIDE DERIVATIVES AS SSTR4 AGONISTS

#10
20230145071
2023-05-11

MASP-2 inhibitors and methods of use

#11
20230115534
2023-04-13

PROGRANULIN MODULATORS AND METHODS OF USING THE SAME

#12
20230039846
2023-02-09

COMPOUNDS AND METHODS OF USE

#13
20230031776
2023-02-02

Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders

#14
20220411378
2022-12-29

SMALL MOLECULES POLYMERASE INHIBITORS

#15
20220323460
2022-10-13

Combination pharmaceutical agents as RSV inhibitors

#16
20220274929
2022-09-01

THIOSEMICARBAZONE COMPOUNDS AND USES THEREOF

#17
20220213042
2022-07-07

SODIUM-HYDROGEN EXCHANGER 3 INHIBITOR COMPOUNDS

#18
20220177488
2022-06-09

SUMO INHIBITOR COMPOUNDS AND USES THEREOF

#19
20210188733
2021-06-24

Process for the halogenation at the alpha-h position of alkylarenes variously substituted on the aromatic ring

#20
20210163471
2021-06-03

PROGRANULIN MODULATORS AND METHODS OF USING THE SAME

#21
20210163402
2021-06-03

Opioid receptor modulators and products and methods related thereto

#22
20210147343
2021-05-20

OPIOID RECEPTOR MODULATORS AND PRODUCTS AND METHODS RELATED THERETO

#23
20210015948
2021-01-21

Manganese-based chelate conjugates for molecular MR imaging

#24
20200268741
2020-08-27

Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders

#25
20190390196
2019-12-26

3′ end caps for RNAi agents for use in RNA interference

#26
20190367452
2019-12-05

MASP-2 inhibitors and methods of use

#27
20190263802
2019-08-29

Compounds and methods of use

#28
20190192535
2019-06-27

Combination pharmaceutical agents as RSV inhibitors

#29
20190077786
2019-03-14

Tetrahydroisoquinolines for use as MOR/NOP dual agonists

#30
20190062279
2019-02-28

Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders

#31
20190008742
2019-01-10

Use of substituted dihydroisoquinolinium salts for treating keratin materials, compositions and implementation processes

#32
20190001003
2019-01-03

Manganese-based chelate conjugates for molecular MR imaging

#33
20180298020
2018-10-18

Piperidine derivative and preparation method and pharmaceutical use thereof

#34
20180265476
2018-09-20

Condensed ring derivative, and preparation method, intermediate, pharmaceutical composition and use thereof

#35
20180263934
2018-09-20

Necrosis inhibitors

#36
20180251428
2018-09-06

Method for the production of praziquantel and precursors thereof

#37
20180072678
2018-03-15

Condensed ring derivative, and preparation method, intermediate, pharmaceutical composition and use thereof

#38
20170320873
2017-11-09

Method for the production of Praziquantel and precursors thereof

#39
20170253593
2017-09-07

Inhibitors of the fibroblast growth factor receptor

#40
20170144973
2017-05-25

Heterocyclic compounds and their use as retinoid-related orphan receptor (ROR) gamma-T inhibitors

#41
20160329500
2016-11-10

Polycyclic compound and organic electronic device comprising the same

#42
20160304863
2016-10-20

3′end caps for RNAi agents for use in RNA interference

#43
20160176873
2016-06-23

Heterocyclic compound

#44
20160176872
2016-06-23

Heterocyclic compound

#45
20160176822
2016-06-23

Heterocyclic compound

#46
20160060282
2016-03-03

Method for producing novel organometallic complex and amine compound

#47
20160046583
2016-02-18

Isoquinoline derivatives

#48
20160039786
2016-02-11

Method for producing 3,4-dihydroisoquinoline derivatives and production intermediates of same

#49
20160002169
2016-01-07

Heterocyclic compound

#50
20150274713
2015-10-01

Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin

#51
20150197519
2015-07-16

Inhibitors of the fibroblast growth factor receptor

#52
20150190389
2015-07-09

Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorder

#53
20150126517
2015-05-07

Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof

#54
20150099732
2015-04-09

3-aryl-5-substituted-isoquinolin-1-one compounds and their therapeutic use

#55
20150065538
2015-03-05

TRPA1 antagonists

#56
20140370556
2014-12-18

Method for preparing (R)-praziquantel

#57
20140370555
2014-12-18

Method for preparing (R)-praziquantel

#58
20140323518
2014-10-30

Estrogen receptor ligands

#59
20140243524
2014-08-28

Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin

#60
20140151670
2014-06-05

Polycyclic compound and organic electronic device comprising the same

#61
20140148453
2014-05-29

Sulfonamide compounds useful as CYP17 inhibitors

#62
20140135327
2014-05-15

N- (2 -AMINOPHENYL) BENZAMIDE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS

#63
20140107074
2014-04-17

Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders

#64
20130274287
2013-10-17

Phenyl-tetrahydroisoquinoline derivatives

#65
20130274285
2013-10-17

Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders

#66
20130184241
2013-07-18

Naphthalene derivative

#67
20130178457
2013-07-11

Cannabinoid receptor modulators

#68
20130116278
2013-05-09

Antimicrobial agents

#69
20130116216
2013-05-09

Transglutaminase TG2 inhibitors, pharmaceutical compositions, and methods of use thereof

#70
20130018046
2013-01-17

Acetylenic heteroaryl compounds

#71
20130005965
2013-01-03

Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin

#72
20120263670
2012-10-18

Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders

#73
20120196851
2012-08-02

Wnt pathway antagonists

#74
20120189537
2012-07-26

Nitrile derivatives and their pharmaceutical use and compositions

#75
20120142727
2012-06-07

Nitrogenous-ring acylguanidine derivative

#76
20120122834
2012-05-17

Small molecule CD4 mimetics and uses thereof

#77
20120101097
2012-04-26

ARYL SULFONAMIDES

#78
20120064062
2012-03-15

INHIBITORS OF BACTERIAL PLASMINOGEN ACTIVATORS

#79
20120040936
2012-02-16

Cyclic compound having substituted phenyl group

#80
20110275797
2011-11-10

N-acyl anthranilic acid derivative or salt thereof

#81
20110237595
2011-09-29

DERIVATIVES OF HETEROARYL-ALKYLCARBAMATES, METHODS FOR THEIR PREPARATION AND USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS

#82
20110201610
2011-08-18

ARYL SULFONAMIDES

#83
20110098285
2011-04-28

Bicyclic-substituted amines as histamine-3 receptor ligands

#84
20110082130
2011-04-07

PIPERAZINYL OXOALKYL TETRAHYDROISOQUINOLINES AND RELATED ANALOGUES

#85
20100331312
2010-12-30

MODULATORS OF THE HISTAMINE H3 RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO

#86
20100292242
2010-11-18

Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof

#87
20100267945
2010-10-21

Amine derivative having NPY Y5 receptor antagonistic activity

#88
20100168154
2010-07-01

1-substituted tetrahydroisoquinoline compound

#89
20100130545
2010-05-27

Bridged six-membered ring compounds

#90
20100120844
2010-05-13

Tetrahydroisoquinoline compound

#91
20100069405
2010-03-18

DERIVATIVES OF HETEROARYL-ALKYLCARBAMATES, METHODS FOR THEIR PREPARATION AND USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS

#92
20100063027
2010-03-11

Amine derivative having NPY Y5 receptor antagonistic activity

#93
20090325962
2009-12-31

TYROSINE DERIVATIVE

#94
20090318454
2009-12-24

NOVEL ANTIOXIDANTS AND METHODS OF TREATMENT

#95
20090291949
2009-11-26

SUBSTITUTE ISOQUINOLINES USEFUL IN THE TREATMENT OF DISEASES SUCH AS CANCER AND ATHEROSCLEROSIS

#96
20090275607
2009-11-05

Tetrahydro isoquinoline derivatives, preparation methods and medicinal uses thereof

#97
20090264480
2009-10-22

TRPA1 antagonists

#98
20090253906
2009-10-08

Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin

#99
20090176781
2009-07-09

Acetylenic heteroaryl compounds

#100
20090148382
2009-06-11

Technetium- and rhenium-bis(heteroaryl) complexes, and methods of use thereof

#101
20090118453
2009-05-07

Metal complexes

#102
20090099229
2009-04-16

Isoquinolines as IGF-1R inhibitors

#103
20090054420
2009-02-26

Bicyclic-substituted amines as histamine-3 receptor ligands

#104
20090048443
2009-02-19

Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin

#105
20090036679
2009-02-05

METHOD FOR RESOLVING ENANTIOMERS FROM RACEMIC MIXTURE HAVING CHIRAL CARBON IN ALPHA POSITION OF NITROGEN

#106
20080318952
2008-12-25

Diaryl-substituted tetrahydroisoquinolines as histamine Hreceptor and serotonin transporter modulators

#107
20080242861
2008-10-02

Synthesis of amino-protected cyclohexane-1,4-diyldimethanamine and its derivatives

#108
20080234272
2008-09-25

Piperazines as antimalarial agents

#109
20080194621
2008-08-14

Substituted 4-phenyltetrahydroisoquinolines, process for their preparation, pharmaceutical compositions and therapeutic use

#110
20080176838
2008-07-24

Dpp-IV Inhibitors

#111
20080161345
2008-07-03

Aryl sulfonamides

#112
20080139610
2008-06-12

Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators

#113
20080111473
2008-05-15

Anthracene derivative and organic electroluminescent element using the same

#114
20080025915
2008-01-31

Technetium- and rhenium-bis (heteroaryl) complexes, and methods of use thereof

#115
20070265301
2007-11-15

Dpp-IV Inhibitors

#116
20070265248
2007-11-15

Substituted piperazines and methods of use

#117
20070249665
2007-10-25

1-aryl-4-substituted isoquinolines

#118
20070232591
2007-10-04

Piperazinyl oxoalkyl tetrahydroisoquinolines and related analogues

#119
20070225365
2007-09-27

CETP inhibitors

#120
20070225323
2007-09-27

Substituted 4-phenyltetrahydroisoquinolines, pharmaceutical compositions thereof, methods for their preparation and therapeutic use

#121
20070224447
2007-09-27

Organometallic Complex, Luminescent Solid, Organic el Element and Organic el Display

#122
20070205412
2007-09-06

Anthracene derivative and organic electronic device using the same

#123
20070203118
2007-08-30

SUBSTITUTED TETRAHYDROISOQUINOLINES USED IN THE FORM OF MMP INHIBITORS, METHOD FOR THE PRODUCTION AND USE THEREOF IN THE FORM OF DRUGS

#124
20070197522
2007-08-23

Dpp-iv inhibitors

#125
20070129399
2007-06-07

Tetrahydroisoquinoline-and tetrahydrobenzazepine derivatives as igf-1 r inhibitors

#126
20070027158
2007-02-01

High affinity small molecule C5a receptor modulators

#127
20070021426
2007-01-25

Derivatives of heteroaryl-alkylcarbamates, methods for their preparation and use thereof as fatty acid amido hydrolase enzyme inhibitors

#128
20060276450
2006-12-07

Isoquinoline potassium channel inhibitors

#129
20060194837
2006-08-31

Tetrahydroisoquinoline compounds

#130
20060194798
2006-08-31

Bicyclic-substituted amines as histamine-3 receptor ligands

#131
20060167054
2006-07-27

Immunomodulation with novel pharmaceutical compositions

#132
20060122388
2006-06-08

Thiocarbamate inhibitors of alpha-4 integrins

#133
20060063766
2006-03-23

Use of aryl- and heteroaryl-substituted tetrahydroisoquinolines to block reuptake of norepinephrine, dopamine, and serotonin

#134
20060052378
2006-03-09

Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin

#135
20060014752
2006-01-19

Heterocyclic anti-epileptogenic agents and methods of use thereof

#136
20050124652
2005-06-09

Guanidino compounds

#137
20050101584
2005-05-12

Selective estrogen receptor-β ligands

#138
20050070719
2005-03-31

Inhibitors of dipeptidyl peptidase iv

#139
20050042407
2005-02-24

Optical data carrier comprising a cyanine dye as light-absorbent compound in the information layer