ClassID:

94325

C07D221/22 - CPC Classification

Classification description:

Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups  -  condensed with carbocyclic rings or ring systems Bridged ring systems

Sub-classes:
Recent Application in this class:
#1
20260116858
2026-04-30

NOVEL LAPPACONITINE DERIVATIVE AND USE THEREOF

#2
20260022098
2026-01-22

BULLEYACONITINE A DERIVATIVE WITH ANALGESIC ACTIVITY, AND PREPARATION METHOD AND APPLICATION THEREOF

#3
20260022097
2026-01-22

SELECTIVE OPIOID RECEPTOR AGONISTS AND ANTAGONISTS

#4
20250059200
2025-02-20

PROCESS FOR C-H INSERTION BY GEM-HYDROGENATION OF AN INTERNAL ALKYNE

#5
20240398959
2024-12-05

C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION

#6
20240391877
2024-11-28

COMPOUND AS INHIBITOR OF COMPLEMENT FACTOR D, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF

#7
20240376041
2024-11-14

METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS

#8
20240343692
2024-10-17

SELECTIVE PSYCHEDELIC COMPOUNDS

#9
20240150290
2024-05-09

HETEROCYCLIC P2Y14 RECEPTOR ANTAGONISTS

#10
20240124394
2024-04-18

Carboxylic Acid Containing Indanyl Compounds for the Treatment of Neurodegenerative Diseases

#11
20240025843
2024-01-25

Methods and compositions for terpenoid synthesis

#12
20230174484
2023-06-08

ANTAGONISTS OF GPR39 PROTEIN

#13
20230158017
2023-05-25

Methods for treating depressive symptoms

#14
20230144767
2023-05-11

TARGETED NITROXIDE AGENTS

#15
20230121302
2023-04-20

Methods of iron catalyzed C-H bond amination

#16
20220401430
2022-12-22

ALLOSTERIC MODULATORS OF THE MU OPIOID RECEPTOR

#17
20220313826
2022-10-06

C-carbon linked glutarimide degronimers for target protein degradation

#18
20220249411
2022-08-11

CALIXARENE COMPOUNDS AND USES THEREOF

#19
20220185781
2022-06-16

BULLEYACONITINE D CRYSTAL AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

#20
20220153704
2022-05-19

CRYSTAL FORM E OF BULLEYACONITINE A, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

#21
20220073469
2022-03-10

Process for the preparation of exo-tert-butyl N-(3-azabicyclo[3.2.1]octan-8-yl)carbamate

#22
20220064123
2022-03-03

(−)-huperzine A processes and related compositions and methods of treatment

#23
20220064122
2022-03-03

Analogs of dextromethorphan with balanced receptor activities

#24
20210371460
2021-12-02

TARGETED NITROXIDE AGENTS

#25
20210078947
2021-03-18

Therapeutic compounds and methods of use thereof

#26
20210040042
2021-02-11

Method for preparing mesaconine and related intermediaries thereof

#27
20210000818
2021-01-07

Methods for treating depressive symptoms

#28
20200392086
2020-12-17

(−)-huperzine A processes and related compositions and methods of treatment

#29
20200361896
2020-11-19

Tricyclic compounds as histone methyltransferase inhibitors

#30
20200345718
2020-11-05

Morphinan Derivatives for the Treatment of Drug Overdose

#31
20200339514
2020-10-29

Crystalline forms of mesaconine and preparation methods therefor

#32
20200317730
2020-10-08

TARGETED NITROXIDE AGENTS

#33
20200276177
2020-09-03

Allosteric modulators of the mu opioid receptor

#34
20200140387
2020-05-07

Tetrahydroisoquinolines as selective NADPH oxidase 2 inhibitors

#35
20200109118
2020-04-09

(−)-huperzine A processes and related compositions and methods of treatment

#36
20200069646
2020-03-05

Inhibitors of indoleamine 2,3-dioxygenase and methods of their use

#37
20190337911
2019-11-07

Centrally active and orally bioavailable antidotes for organophosphate exposure and methods for making and using them

#38
20190270700
2019-09-05

Methods and compositions for terpenoid synthesis

#39
20190210972
2019-07-11

Methods of resolving racemic mixture to obtain (−)-Huperzine A

#40
20190202820
2019-07-04

PROCESS FOR PRODUCING FLUORINATED COMPOUNDS USING ALCOHOL SOLVENT HAVING CARBONYL GROUP

#41
20190167666
2019-06-06

Methods for treating depressive symptoms

#42
20190135733
2019-05-09

Caspase inhibitor and pharmaceutical composition, use and therapeutic method thereof

#43
20190119237
2019-04-25

Centrally active and orally bioavailable antidotes for organophosphate exposure and methods for making and using them

#44
20190077789
2019-03-14

Piperazinyl norbenzomorphan compounds and methods for using the same

#45
20190076542
2019-03-14

C3-carbon linked glutarimide degronimers for target protein degradation

#46
20190031607
2019-01-31

Therapeutic compounds and methods of use thereof

#47
20190030020
2019-01-31

Allosteric modulators of the mu opioid receptor

#48
20190016682
2019-01-17

Azepane derivatives and methods of treating hepatitis B infections

#49
20180327421
2018-11-15

5-HT3 receptor antagonists

#50
20180298054
2018-10-18

Targeted nitroxide agents

#51
20180237395
2018-08-23

(−)-huperzine A processes and related compositions and methods of treatment

#52
20180127369
2018-05-10

LSD1 inhibitors

#53
20180072758
2018-03-15

5HT3 RECEPTOR ANTAGONISTS

#54
20180036436
2018-02-08

Ethylenediaminetetraacetic acid bis(amide) derivatives and their respective complexes with Mn(II) ion for use as MRI contrast agent

#55
20180009762
2018-01-11

TETRAHYDROISOQUINOLINES AS SELECTIVE NADPH OXIDASE 2 INHIBITORS

#56
20170333422
2017-11-23

Morphinan Derivatives for the Treatment of Drug Overdose

#57
20170320855
2017-11-09

Spiroacridine-triazine hybrids and applications for electroluminescent devices

#58
20170305883
2017-10-26

Compositions and Methods for Inhibiting BMP

#59
20170260201
2017-09-14

5-HT3 receptor antagonists

#60
20170240555
2017-08-24

Inhibitors of HIF prolyl hydroxylase

#61
20170216279
2017-08-03

Methods for treating depressive symptoms

#62
20170183308
2017-06-29

LSD1 inhibitors

#63
20170015629
2017-01-19

Azepane derivatives and methods of treating hepatitis B infections

#64
20160340316
2016-11-24

Ring-contracted morphinans and the use thereof

#65
20160251373
2016-09-01

5-HT3 receptor antagonists

#66
20160233443
2016-08-11

Metal complexes

#67
20160226003
2016-08-04

Heterocyclic compounds

#68
20160204358
2016-07-14

Polycyclic compounds

#69
20160190447
2016-06-30

Materials for organic electroluminescent devices

#70
20160185801
2016-06-30

5-HT3 receptor antagonists

#71
20160159745
2016-06-09

Preparation of (−)-huperzine A

#72
20160137692
2016-05-19

Targeted nitroxide agents

#73
20160096808
2016-04-07

Methods of resolving racemic mixture to obtain (−)-huperzine A

#74
20160083351
2016-03-24

Tetrahydroisoquinolines as selective NADPH oxidase 2 inhibitors

#75
20150291624
2015-10-15

5-HT3 receptor antagonists

#76
20150291617
2015-10-15

Thiazole derivatives as alpha 7 nAChR modulators

#77
20150239832
2015-08-27

ANALOGS AND PRODRUGS OF LOOP DIURETICS, INCLUDING BUMETANIDE, FUROSEMIDE AND PIRETANIDE; COMPOSITIONS AND METHODS OF USE

#78
20150225355
2015-08-13

Azepane derivatives and methods of treating hepatitis B infections

#79
20150210647
2015-07-30

ATX modulating agents

#80
20150197735
2015-07-16

7,11-methanocycloocta [b] quinoline derivative as highly functionalizable acetylcholinesterase inhibitors

#81
20150182533
2015-07-02

5-HT3 receptor antagonists

#82
20150158817
2015-06-11

(−)-Huperzine A processes and related compositions and methods of treatment

#83
20150152120
2015-06-04

Methods for one-pot N-demethylation/N-functionalization of morphine and tropane alkaloids

#84
20150126514
2015-05-07

Bridged bicyclic heteroaryl substituted triazoles useful as Axl inhibitors

#85
20150119416
2015-04-30

Carboxamide bioisosteres of opiates

#86
20150099776
2015-04-09

Beta-amyloid-directed multitarget compounds for the treatment of alzheimer's disease

#87
20150072971
2015-03-12

Methods for treating depressive symptoms

#88
20150057443
2015-02-26

Cycloalkyl Amine Compounds

#89
20150051194
2015-02-19

Large substituent, non-phenolic opioids and methods of use thereof

#90
20150031887
2015-01-29

9-azanoradamantane N—oxyl compound and method for producing same, and organic oxidation catalyst and method for oxidizing alcohols using 9-azanoradamantane N—oxyl compound

#91
20140378504
2014-12-25

Method of using substituted 2-Aza-bicyclo[2.2.2]octane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin C

#92
20140378444
2014-12-25

Targeted nitroxide agents

#93
20140350246
2014-11-27

Nitrogen-containing heterocyclic compounds and methods of making the same

#94
20140275545
2014-09-18

8-CARBOXAMIDO-2,6-METHANO-3-BENZAZOCINES

#95
20140275159
2014-09-18

Substituted 2-aza-bicyclo[2.2.2]octane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin C

#96
20140275155
2014-09-18

Substituted bicyclic 1-carboxylic-acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin C

#97
20140194457
2014-07-10

Carboxamide bioisosteres of opiates

#98
20140179669
2014-06-26

Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use

#99
20140179638
2014-06-26

9-aminomethyl substituted tetracycline compounds

#100
20140128400
2014-05-08

Bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors

#101
20130345251
2013-12-26

Large substituent, non-phenolic opioids and methods of use thereof

#102
20130338182
2013-12-19

Morphinans useful as analgesics

#103
20130331569
2013-12-12

Cross-linked cyclic amine compounds and agents for pest control

#104
20130303570
2013-11-14

Modulators of cystic fibrosis transmembrane conductance regulator

#105
20130225628
2013-08-29

Carboxamide bioisosteres of opiates

#106
20130102626
2013-04-25

Targeted nitroxide agents

#107
20130045169
2013-02-21

Compounds having muscarinic receptor antagonist and beta2 Adrenergic receptor agonist activity

#108
20130029941
2013-01-31

7,11-methanocycloocta [B] quinoline derivative as highly functionalizable acetylcholinesterase inhibitors

#109
20130018051
2013-01-17

Bridged bicyclic heteroaryl substituted triazoles useful as inhibitors

#110
20120302591
2012-11-29

Methods of using 8-carboxamido-2,6-methano-3-benzazocines

#111
20120295923
2012-11-22

Aminocyclohexanes and Aminotetrahydropyrans and Related Compounds As Gamma-Secretase Modulators

#112
20120271046
2012-10-25

NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING THE SAME

#113
20120238526
2012-09-20

Aconitine compounds, compositions, uses, and preparation thereof

#114
20120209004
2012-08-16

Process for production of azabicycloalkanol derivative

#115
20120208841
2012-08-16

Modulators of cystic fibrosis transmembrane conductance regulator

#116
20120165320
2012-06-28

Azabicyclohexanes

#117
20120156219
2012-06-21

NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND MEDICINAL USE THEREOF

#118
20120149900
2012-06-14

FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF

#119
20110313163
2011-12-22

Methods for one-pot -demethylation/-functionalization of morphine and tropane alkaloids

#120
20110306633
2011-12-15

SELECTIVE M4 RECEPTOR ANTAGONIST AND ITS MEDICAL USE

#121
20110306603
2011-12-15

Large substituent, non-phenolic opioids and methods of use thereof

#122
20110301187
2011-12-08

Bis [O-(14-benzoylaconine-8-yl)] esters

#123
20110269791
2011-11-03

Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use

#124
20110257389
2011-10-20

Cross-linked cyclic amine compounds and agents for pest control

#125
20110230511
2011-09-22

Carboxamide bioisosteres of opiates

#126
20110207763
2011-08-25

8-carboxamido-2,6-methano-3-benzazocines

#127
20110136848
2011-06-09

Morphinan derivatives for the treatment of drug overdose

#128
20110105512
2011-05-05

Bridged bicyclic heteroaryl substituted triazoles useful as AXL inhibitors

#129
20100316607
2010-12-16

Hepatitis C virus inhibitors

#130
20100221259
2010-09-02

Nitrogen-containing heterocyclic compounds and medicinal use thereof

#131
20100190985
2010-07-29

Heterodiamondoids

#132
20100179183
2010-07-15

PHARMACEUTICAL COMPOSITIONS AND METHODS FOR RELIEVING PAIN AND TREATING CENTRAL NERVOUS SYSTEM DISORDERS

#133
20100173968
2010-07-08

Sub-type selective azabicycloalkane derivatives

#134
20100160328
2010-06-24

NEW COMPOUNDS USEFUL FOR DPP-IV ENZYME INHIBITION

#135
20100152228
2010-06-17

Pharmaceutical compositions and methods for relieving pain and treating central nervous system disorders

#136
20100113508
2010-05-06

Modulators of cystic fibrosis transmembrane conductance regulator

#137
20100094012
2010-04-15

Heterodiamondoids

#138
20100056497
2010-03-04

AMIDE DERIVATIVE

#139
20100035869
2010-02-11

Targeted nitroxide agents

#140
20100016545
2010-01-21

Process for the covalent coupling of two molecules by means of a diels-alder reaction with inverse electron requirement

#141
20100004455
2010-01-07

Method for producing piperidin-4-one derivative

#142
20090318694
2009-12-24

Cross-linked cyclic amine compounds and agents for pest control

#143
20090318491
2009-12-24

Cytisine and Acetylcholine Analogs and Methods of Treating Mood Disorders

#144
20090259046
2009-10-15

Cyclic amine compounds and agents for pest control

#145
20090259045
2009-10-15

Process for production of azabicycloalkanol derivative

#146
20090247754
2009-10-01

METHOD OF PREPARING HUPERZINE A AND DERIVATIVES THEREOF

#147
20090247562
2009-10-01

Large substituent, non-phenolic opioids and methods of use thereof

#148
20090227582
2009-09-10

Tetrahydroquinolinones and their use as modulators of metabotropic glutamate receptors

#149
20090176705
2009-07-09

Modular platform for targeted therapeutic delivery

#150
20090156818
2009-06-18

Process and compounds for the production of (+)opiates

#151
20090118320
2009-05-07

Derivatives of 5,9-methanocycloocta[b]pyridin-2-(1H)-one, their preparation and use as analgesics

#152
20090090628
2009-04-09

NUCLEIC ACID DERIVATIVES AND METHODS OF USE

#153
20090048447
2009-02-19

Method for decreasing opioid metabolism

#154
20080312292
2008-12-18

Antipruritics

#155
20080261999
2008-10-23

Azabicycloalkane Derivatives Useful as Nicotinic Acetylcholine Receptor Agonists

#156
20080242693
2008-10-02

Pharmaceutical Compositions and Methods for Relieving Pain and Treating Central Nervous System Disorders

#157
20080214537
2008-09-04

BRIDGED PHENANTHRIDINES

#158
20080207689
2008-08-28

Formamide derivatives for the treatment of diseases

#159
20080009489
2008-01-10

ANDROGEN RECEPTOR MODULATORS AND METHOD OF TREATING DISEASE USING THE SAME

#160
20070275973
2007-11-29

ARYL FUSED AZAPOLYCYCLIC COMPOUNDS

#161
20070270454
2007-11-22

Huperzine a compound for treatment of alzheimer's disease

#162
20070241065
2007-10-18

Extraction of alkaloids from opium

#163
20070185151
2007-08-09

Azabicyclic, azatricyclic and azaspirocyclic derivatives of aminocyclohexane NMDA, 5HT3 and neuronal nicotinic receptor antagonists

#164
20070167459
2007-07-19

Nitrogen-containing heterocyclic compounds and medicinal use thereof

#165
20070082922
2007-04-12

Huperzine a prodrugs and uses thereof

#166
20070021457
2007-01-25

Large substituent, non-phenolic opioids

#167
20070004679
2007-01-04

Androgen receptor modulators and methods of treating disease using the same

#168
20060276487
2006-12-07

Compounds useful for DPP-IV enzyme inhibition

#169
20060241135
2006-10-26

Opioid receptor agonist compounds and their use in treatment of pain

#170
20060223840
2006-10-05

Substituted piperidine compounds and methods of their use

#171
20060217534
2006-09-28

Bis (amino acid) molecular scaffolds

#172
20060183870
2006-08-17

Heterodiamondoids

#173
20060167036
2006-07-27

Tyrosine kinase inhibitors

#174
20060030580
2006-02-09

Method for decreasing opioid metabolism

#175
20060019983
2006-01-26

Azabicyclic, azatricyclic and azaspirocyclic derivatives of aminocyclohexane NMDA, 5HT3 and neuronal nicotinic receptor antagonists

#176
20060019982
2006-01-26

Azabicyclic, azatricyclic and azaspirocyclic derivatives of aminocyclohexane NMDA, 5HT, and neuronal nicotinic receptor antagonists

#177
20060014957
2006-01-19

Resolution of an aryl-fused azapolycyclic compound

#178
20060014739
2006-01-19

Androgen receptor modulators and method of treating disease using the same

#179
20060004001
2006-01-05

Tetrahydroquinolones and their use as modulators of metabotropic glutamate receptors

#180
20050288284
2005-12-29

Tetrahydroquinolones and their use as modulators of metabotropic glutamate receptors

#181
20050282823
2005-12-22

Pharmaceutical compositions and methods for relieving pain and treating central nervous system disorders

#182
20050215590
2005-09-29

Formamide derivatives for the treatment of diseases

#183
20050203123
2005-09-15

Substituted piperidine compounds and methods of their use

#184
20050197361
2005-09-08

Tetrahydroquinolinones and their use as antagonists of metabotropic glutamate receptors

#185
20050101590
2005-05-12

Antipruritics

#186
20050090519
2005-04-28

1-alkyl-4-(3-substitutedphenyl)piperidines

#187
20050059712
2005-03-17

Acylsulfonamides as inhibitors of steroid sulfatase

#188
20050020616
2005-01-27

Aryl fused azapolycyclic compounds