Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof

Compounds and their use as BACE inhibitors

Nuclear transport modulators and uses thereof

Annelated phenoxyacetamides

GLP-1 receptor modulators

EGFR inhibitor, preparation method and use thereof

Diheteroaryl histone deacetylase inhibitors and their use in therapy

Nonanoic and decanoic acid derivatives and uses thereof

Modulators of calcium release-activated calcium channel

Heteroarylamide inhibitors of TBK1

1-pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl) oxy) napththalen-1-yl) ureas as P38 MAP knase inhibitors

Dual-warhead covalent inhibitors of FGFR-4

Aminopyridine compounds useful as inhibitors of protein prenylation

Heterocyclic compounds as pesticides

SMALL MOLECULE INHIBITORS OF NECROPTOSIS

QUINAZOLINE DERIVATIVES SUBSTITUTED BY ANILINE, PREPARATION METHOD AND USE THEREOF

Carbamate, ester, and ketone compounds for treatment of complement mediated disorders

Amide compounds for treatment of complement mediated disorders

Glycosidase inhibitors

HETEROCYCLIC RING AND CARBOCYCLIC DERIVATIVE

Compositions and methods for inhibition of the JAK pathway

Pyrimidines as sodium channel blockers

Kinase inhibitors

Therapeutic compounds as inhibitors of the orexin-1 receptor

1,2,4-triazine-4-amine derivatives

Small molecule regulators of steroid receptor coactivators and methods of use thereof

1,4-disubstituted pyridazine analogs there of and methods for treating SMN-deficiency-related conditions

Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules

Compounds for the inhibition of cyclophilins and uses thereof

COMPOUNDS FOR THE INHIBITION OF CYCLOPHILINS AND USES THEREOF

Diamide macrocycles that are FXIa inhibitors

2-aminopyrimidine compound and pharmaceutical composition and use thereof

PYRIMIDINEDIONE COMPOUNDS

Benzenesulfonyl-asymmetric ureas and medical uses thereof

Indazole compounds as FGFR kinase inhibitor, preparation and use thereof

Therapeutic compounds and uses thereof

Benzazepine sulfonamide compounds

SMALL LIPOPEPTIDOMIMETIC INHIBITORS OF GHRELIN O-ACYL TRANSFERASE

Substituted phenylpyrrolecarboxamides with therapeutic activity in HIV

Organic electroluminescent element, display device, lighting device, PI-conjugated compound, and light-emitting thin film

Certain protein kinase inhibitors

Quinazoline derivatives, compositions thereof, and use as pharmaceuticals

SUBSTITUTED URACILS AS CHYMASE INHIBITORS

Substituted diaminocarboxamide and diaminocarbonitrile pyrimidines, compositions thereof, and methods of treatment therewith

Pyrazolyl guanidine FF-ATPase inhibitors and therapeutic uses thereof

Compounds as CRTH2 antagonist and uses thereof

Nonsteroidal and steroidal compounds with potent androgen receptor down-regulation and anti prostate cancer activity

Methods for treating pulmonary emphysema using substituted 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides inhibitors of Cathepsin C

Biaryl amide compounds as kinase inhibitors

Androgen receptor modulating compounds

Sulfoximine substituted quinazolines for pharmaceutical compositions

Compounds

Heteroaryl orexin receptor antagonists

Heterocyclic compound

Nampt Inhibitors

N4-PHENYL-QUINAZOLINE-4-AMINE DERIVATIVES AND RELATED COMPOUNDS AS ERBB TYPE I RECEPTOR TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES

ALK kinase inhibitor, and preparation method and uses thereof

Inhibitors of IRAK4 activity

Methods and compositions for inhibition of Ras

Compounds

PHARMACEUTICALLY ACTIVE PYRAZINE DERIVATIVES

Inhibitors of low molecular weight protein tyrosine phosphatase and uses thereof

SUBSTITUTED PYRIMIDINES AS INHIBITORS OF HIF PROLYL HYDROXYLASE

Octahydrocyclopentapyrroles, their preparation and use

Substituted Pyrrolidine Carboxamide Compounds

Composition and methods of use of small molecules as binding ligands for the modulation of proprotein convertase subtilisin/kexin type 9(PCSK9) protein activity

2,4-pyrimidinediamine compounds and their uses

3-alkyl-5-fluoro-4-substituted-imino-3,4-dihydropyrimidin-2(1)-one derivatives as fungicides

G protein-coupled receptor kinase 2 inhibitors and methods for use of the same

Small molecule agonists of neurotensin receptor 1

Heterocycle and carbocycle derivatives having TrkA inhibitory activity

Pyrimidine derivatives for the treatment of viral infections

Heterocyclic compounds as NaV channel inhibitors and uses thereof

T-type calcium channel modulator and uses thereof

Substituted 6,7-dihydro-5H-benzo[7]annulene compounds, processes for their preparation and therapeutic uses thereof

Quaternary amine compounds and antibody-drug conjugates thereof

Compounds, compositions and methods

PHTHALAZINONE DERIVATIVES

Quinazoline derivative

Pyridinyloxy- and phenyloxy-pyrazolyl compounds

Compounds for preventing, inhibiting, or treating cancer, AIDS and/or premature aging

2,2,2-trifluoroethyl-thiadiazines

Indoline sulfonamide inhibitors of DapE and NDM-1 and use of the same

Substituted 1,2,3-triazoles as NR2B-selective NMDA modulators

Forms and compositions of an ERK inhibitor

Pyrrolidinone derivatives as MetAP-2 inhibitors

Potent dual BRD4-kinase inhibitors as cancer therapeutics

Pyrrolopyrimidine compounds as inhibitors of protein kinases

TLR-independent small molecule adjuvants

Ligand-directed covalent modification of protein

Inhibitors of IRAK4 activity

Hepatitis B antiviral agents

Pyrimidine-2,4-diamine derivatives for treatment of cancer

Metabotropic glutamate receptor negative allosteric modulators (NAMS) and uses thereof

Bicyclo[3.2.1]Octyl Amide Derivatives and Uses of Same

SUBSTITUTED BENZENE AND 6,5-FUSED BICYCLIC HETEROARYL COMPOUNDS

Additive for imparting ultraviolet absorbency and/or high refractive index to matrix, and resin member using same

Pyrrolidinyl urea, pyrrolidinyl thiourea and pyrrolidinyl guanidine compounds as TrkA kinase inhibitors

Benzotriazine Oxides as Drugs Targeting Mycobacterium Tuberculosis

Aminopyrimidine derivatives for use as modulators of kinase activity

SUBSTITUTED 1,2,3,4-TETRAHYDROCYCLOPENTA[b]INDOL-3-YL)ACETIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS

Activators of autophagic flux and phospholipase D and clearance of protein aggregates including tau and treatment of proteinopathies

Synthesis of an antiviral compound

Substituted azaspiro(4.5)decane derivatives

ERK inhibitors and uses thereof

6-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same

Pyrimidine carboxamides as sodium channel blockers

Process for preparing pyrazoles

3-aryl propiolonitrile compounds for thiol labeling

BIOCIDAL COATINGS AND METHODS FOR MAKING SAME

4,6-disubstituted aminopyrimidine derivatives have anti-HIV activity

Inhibitors of histone deacetylase

Compositions, methods, and systems for the synthesis and use of imaging agents

Heterocyclic compounds having cholesterol 24-hydroxylase activity

Inhibitors of bacterial DNA gyrase with efficacy against gram-negative bacteria

Heteroaryl substituted compounds as RORγ inhibitors

MTH1 inhibitors for treatment of cancer

3-(Carboxymethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives

Process for producing alkynylketone derivative

Bifunctional compounds and use for reducing uric acid levels

3-(Carboxyethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives

Estrogen receptor modulators and uses thereof

Urea and amide derivatives of aminoalkylpiperazines and use thereof

5-acylsulfanyl-histidine compounds as precursors of the corresponding 5-sulfanylhistidines and their disulfides

Imidazol- or 1,2,4-triazol-derivatives and their use

BIS(ARYL)CATECHOL DERIVATIVES AS HERBICIDES

Pyrazole compounds and methods of making and using same

Amino compounds for treatment of complement mediated disorders

Neprilysin inhibitors

Heterocyclic amides as kinase inhibitors

Benzimidazole derivatives as ERBB tyrosine kinase inhibitors for the treatment of cancer

Difluoromethoxy compound with low bioactivation potential for the reduction of beta-amyloid production

Quinoxaline compounds and uses thereof

Biotin Derivatives

Protein kinase conjugates and inhibitors

Substituted indole Mcl-1 inhibitors

Antiviral compounds and methods using same

Pyridazine compounds as JAK inhibitors

Inhibitors of the fibroblast growth factor receptor

Fused bicyclic 2,4-diaminopyrimidine derivative as a dual ALK and FAK inhibitor

Apelin receptor (APJ) agonists and uses thereof

2-amino-benzimidazole derivatives and their use as 5-lipoxygenase and/or prostaglandin E synthase inhibitors

Five-membered heterocycles useful as serine protease inhibitors

6-substituted quinazolinone inhibitors

Ethers, secondary amines and derivatives thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto

N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors

Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3

Water-soluble activatable molecular probes, intermediates for the synthesis thereof and associated detection methods

Pyrimidinone derivative having autotaxin-inhibitory activity

MULTIVALENT RAS BINDING COMPOUNDS

TrKA kinase inhibitors, compositions and methods thereof

Compounds and methods for inhibiting fascin

Substituted pyrimidines for inhibiting Raf kinase activity

Histone demethylase inhibitors

Substituted indazole derivatives active as kinase inhibitors

Quinazolinone derivatives as PARP inhibitors

FUNCTIONALISED AND SUBSTITUTED INDOLES AS ANTI-CANCER AGENTS

Combinations of AKT inhibitor compounds and chemotherapeutic agents, and methods of use

Anti-depression compounds

TRPV1 vanilloid receptor antagonists with a bicyclic portion

Benzimidazole derivatives as kinase inhibitors

Amino quinazolines as kinase inhibitors

NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND

Compounds for selective histone deacetylase inhibitors, and pharmaceutical composition comprising the same

Compositions, methods, and systems for the synthesis and use of imaging agents

Substituted asymmetric ureas as modulators of ghrelin receptor activity

Pyrimidine-5-carboxamides as spleen tyrosine kinase inhibitors

Pyrimidine-2,4-diamine derivative and anticancer pharmaceutical composition comprising same as effective ingredient

Substituted azetidine derivatives

Tetrazole-substituted arylamides as PXand PXantagonists

Nuclear Transport Modulators And Uses Thereof

Compositions and methods for inhibition of the JAK pathway

Compounds for the treatment of HIV

Inhibitors of lysine specific demethylase-1

Neprilysin inhibitors

Methods for treating MS using pyrimidine and pyridine compounds with BTK inhibitory activity

Cyclic amine azaheterocyclic carboxamides

Tetrazolones as a carboxylic acid bioisosteres

6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides

Isoindoline, azaisoindoline, dihydroindenone and dihydroazaindenone inhibitors of Mnk1 and Mnk2

Compounds

HIV REPLICATION INHIBITING PYRIMIDINES

COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY

Auristatin derivatives and conjugates thereof

2-(2-methylamino-pyrimidin-4-yl)-1h-indole-5-carboxylic acid [(S)-1-carbamoyl-2-(phenyl-pyrimidin-2-yl-amino)-ethyl]-amide for use in the treatment of pain associated to osteoarthritis

Compounds having muscarinic receptor antagonist and BETA2 adrenergic receptor agonist activity

Tetrazolinone compound and application thereof

Compound and organic light-emitting device including the same

Compounds and compositions as kinase inhibitors

TrkA kinase inhibitors, compositions and methods thereof

NOVEL EFFECTIVE ANTIVIRAL COMPOUNDS AND METHODS USING SAME

Histone demethylase inhibitors

N-acylethanolamine hydrolyzing acid amidase (NAAA) inhibitors and their use thereof

Phenyl triazole derivative and its use for modulating the GABAreceptor complex

Water-soluble triazabutadienes

Inhibitors of lysine specific demethylase-1

Tyrosine kinase inhibitor and uses thereof

Treatment of GVHD

Dihydroxy aromatic heterocyclic compound

Benzimidazole compounds and medical uses thereof

AMINOPYRAZOLONE DERIVATIVE

TrkA kinase inhibitors, compositions and methods thereof

HETEROCYCLIC INHIBITORS OF THE SODIUM CHANNEL

Compounds useful as immunomodulators

Indole derivatives for use in medicine

Tetrazolinone compound and application thereof

Anthracene derivative, light-emitting element using the same, and light-emitting device using the same

Carboxamide derivatives and use thereof

Pyrazole-substituted arylamides as P2Xand P2Xantagonists

Dual inhibitor compounds for use in the treatment of neurodegenerative disorders and alzheimer's disease

Compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions comprising the same

DIAMINOPYRIMIDINES AS P2X3 AND P2X2/3 ANTAGONISTS

Pyrazole compounds and their use as T-type calcium channel blockers

Light-Emitting Element, Display Device, Electronic Device, and Lighting Device

Substituted indol-5-ol derivatives and their therapeutical applications

Compositions, methods of use, and methods of treatment

Benzimidazole derivatives and uses thereof

1 -((3S,4R)-4-(3-fluorophenyl)-1-(2-methoxyethyl)pyrrolidin-3-yl)-3-(4-methyl-3-(2-methylpyrimidin-5-yl)-1-phenyl-1H-pyrazol-5-yl)urea as a TrkA kinase inhibitor

Phenyl and benzodioxinyl substituted indazoles derivatives

Prostaglandin receptor EP2 antagonists, derivatives, compositions, and uses related thereto

ANTIVIRAL COMPOUNDS

2,4-pyrimidinediamine compounds and their uses

Small molecule inhibitor of MYD88 for therapeutic treatment against alphavirus and staphylococcal enterotoxin infections and toxin exposure

Pyrazolyl-substituted heteroaryls and their use as medicaments

Treatments for gastrointestinal conditions

Guanidine compounds and use thereof

Multivalent ligands targeting VEGFR

Crystal form of dabigatran etexilate mesylate and preparation method and use thereof

Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto

Methods of regioselective synthesis of 2,4-disubstituted pyrimidines

Human plasma kallikrein inhibitors

Benzomorphan analogs and use thereof

Treatment of brain and central nervous system tumors

CDK8-CDK19 selective inhibitors and their use in anti-metastatic and chemopreventative methods for cancer

Pyridine and pyrazine derivative for the treatment of CF

Selective octahydro-cyclopenta[C] pyrrole negative modulators of NR2B

Derivatives of 6-(2,3-dichlorophenyl)-1,2,4-triazin-5-amine

Methods and compositions useful in treating cancer and reducing Wnt mediated effects in a cell

Herbicidal compounds

1,2-substituted cyclopentanes as orexin receptor antagonists

Urea derivative or pharmacologically acceptable salt thereof

NEW PHENYLAZETIDINECARBOXYLATE OR -CARBOXAMIDE COMPOUNDS

Combinations for the treatment of neuroblastoma

Indazole inhibitors of the Wnt signal pathway and therapeutic uses thereof

Fumarate analogs and uses thereof

Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device

Compound for organic electronic element, organic electronic element using the same, and an electronic device thereof

2,3,4,6-tetra-substituted benzene-1,5-diamine derivatives, preparation method therefor and medicinal use thereof

Compositions useful for treating disorders related to kit

Arginine methyltransferase inhibitors and uses thereof

NOVEL ANNELATED PHENOXYACETAMIDES

Small molecule inhibitors of G protein coupled receptor 6 kinases polypeptides

Lactam-containing compounds and derivatives thereof as factor Xa inhibitors

NEW BICYCLIC DERIVATIVES

Annelated benzamides

Uracil derivatives as AXL and c-MET kinase inhibitors

3-CYCLOALKYLAMINOPYRROLIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS

COMPOUNDS AND THERAPEUTICAL USE THEREOF

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS

Benzamide compounds and related methods of use

Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents

Heterocyclic compounds and their use as dopamine D1 ligands

2-amino-pyridine and 2-amino-pyrimidine derivatives and medicinal use thereof

Disubstituted 1, 2, 4-triazine compound

Hydrophobically tagged janus kinase inhibitors and uses thereof

Janus kinase inhibitors and uses thereof

INHIBITORS OF DRUG-RESISTANT MYCOBACTERIUM TUBERCULOSIS

JAK1 inhibitors

ALANINE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE

Nitrogen-containing heteroaryl compounds and methods of use thereof

Heterocyclic compounds and uses thereof

Diazaspirocycloalkane and azaspirocycloalkane

Enhancer of zeste homolog 2 inhibitors

Antibacterial 1-indazole and 1-indole derivatives

Compositions useful for treating disorders related to kit

N-alkoxyamide conjugates as imaging agents

Tetrahydro-benzoimidazolyl modulators of TGR5

Condensed 5-oxazolidinone derivative

Amide-substituted heterocyclic compounds useful as modulators of IL-12, IL-23 and/or IFN alpha responses

Benzamides

Halogenated quinazolin-THF-amines as PDE1 inhibitors

Neprilysin inhibitors

Amido-substituted azole compounds

Spiro compound having azafluorene ring structure, light-emitting material, and organic electroluminescent device

Hepatitis B core protein allosteric modulators

Pyrimidone carboxamide compounds as PDE2 inhibitors

PKM2 modulators and methods for their use

Azepane derivatives and methods of treating hepatitis B infections

Somatostatin receptor subtype 4 (SSTR4) agonists

Cysteine protease inhibitors and uses thereof

Neprilysin inhibitors

Heterocyclic amides as kinase inhibitors

Bicyclic lactams and methods of use thereof

Heteroaryl compounds as BTK inhibitors and uses thereof

NOVEL HETEROBICYCLIC COMPOUNDS AS KAPPA OPIOID AGONISTS

1-pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl)oxy)napththalen-1-yl) ureas as P38 MAP knase inhibitors

Pyrimidine FGFR4 inhibitors

Azaspiro derivatives as TRPM8 antagonists

Substituted heterocyclic acetamides as kappa opioid receptor (KOR) agonists

PIPERIDINE AND PIPERAZINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS AND CANCER