Glucokinase activators

Pyrimidine derivatives for the treatment of viral infections

THIOPYRIMIDINE-BASED COMPOUNDS AND USES THEREOF

Inhibitors of PI3K-delta and methods of their use and manufacture

4-(4-cyano-2-thioaryl)dihydropyrimidinones and their use

N-alkyl lactam ethers, and compositions and uses thereof

Pesticidal pyrazole compounds

Process for the preparation of acylguanidines and acylthioureas

Pyrimidine derivatives that inhibit FAK/PTK2

Substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives useful in the treatment of autoimmune and inflammatory disorders

AMINO-HETEROARYL-CONTAINING PROKINETICIN 1 RECEPTOR ANTAGONISTS

Imidazole based LXR modulators

CDK8-CDK19 selective inhibitors and their use in anti-metastatic and chemopreventative methods for cancer

Therapeutic applications of pro-apoptotic benzodiazepines

SEROTONIN RECEPTOR MODULATOR

Beta amino acid derivatives as integrin antagonists

SELECTIVE HDAC INHIBITORS

Inhibitors of protein kinases

Quinazolinediones and their use

Protein kinase inhibitors

2,4-pyrimidinediamine compounds and their uses

Quinazolines as potassium ion channel inhibitors

Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapy

Small molecule inhibitors of necroptosis

Pyridazinone compounds

Aromatic heterocyclic derivative having TRPV4-inhibiting activity

Fumaric acid salt of 9-[4-(3-chloro-2-fluoro-phenylamino)-7-methoxy-quinazolin-6-yloxy]-1,4-diaza-spiro[5.5]undecan-5-one, its use as a medicament and the preparation thereof

5-fluoro pyrimidine derivatives

N4-phenyl-quinazoline-4-amine derivatives and related compounds as ErbB type I receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases

1-(Arylmethyl)quinazoline-2,4(1,3)-diones as PARP inhibitors and the use thereof

No-releasing nonoate(nitrogen-bound)sulfonamide-linked-coxib anti-cancer agents

Hedgehog antagonists having zinc binding moieties

Precursor compound connected to solid support for manufacturing 18F radiopharmaceutical, method for manufacturing same, and application thereof

Compounds that modulate EGFR activity and methods for treating or preventing conditions therewith

Nitrogen-containing saturated heterocyclic compound

Phenyl amino pyrimidine compounds and uses thereof

Arylsulfonyl pyrazoline carboxamidine derivatives as 5-HTantagonists

Compositions and methods for inhibition of the JAK pathway

ANTIVIRAL COMPOUNDS

Quinazoline based EGFR inhibitors

Nitrogen-containing condensed heterocyclic compound

Phenyl amino pyrimidine compounds and uses thereof

PYRIDINYL- AND PYRAZINYL-METHYLOXY-ARYL DERIVATIVES USEFUL AS INHIBITORS OF SPLEEN TYROSINE KINASE (SYK)

2-phenoxy- and 2-phenylsulfonamide derivatives with CCR3 antagonistic activity for the treatment of inflammatory or immunological disorders

INDOLE DERIVATIVES USEFUL AS CCR2 ANTAGONISTS

SUBSTITUTED 3-AZABICYCLO[3.1.0]HEXANE DERIVATIVES USEFUL AS CCR2 ANTAGONISTS

WNT PATHWAY ANTAGONISTS

Efficient peptide couplings and their use in the synthesis and isolation of a cyclopenta (G) quinazoline trisodium salt

1,2,4-triazine-6-carboxamide kinase inhibitors

2,4- DIAMINOPYRIMIDINE DERIVATIVES

Peptide deformylase inhibitors

Tartrate salts of quinazoline based EGFR inhibitors containing a zinc binding moiety

MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION

Fused ring analogues of anti-fibrotic agents

4,6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES

NOVEL INDOLE MODULATORS OF S1P RECEPTORS

Compounds for the treatment of proliferative disorders

HCV protease inhibitors and uses thereof

Ring-substituted N-pyridinyl amides as kinase inhibitors

Compounds and methods for inhibiting phosphate transport

Pyridinone and pyridazinone derivatives

Certain kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof

Compound for organic light-emitting device and organic light-emitting device including the same

Carbazole derivative, light-emitting element material, light-emitting element, light-emitting device, electronic device, and lighting device

Selective FAK inhibitors

Benzimidazole cannabinoid agonists bearing a substituted heterocyclic group

2,4-pyrimidinediamine compounds and their uses

Quinoline carboxamide derivatives as protein tyrosine kinase inhibitors

Aminoquinazoline and pyridopyrimidine derivatives

Method for applying a first metal onto a second metal, an isolator or semiconductor substrate, and the respective binding units

NOVEL CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE

Nuclear transport modulators and uses thereof

OXYPYRIMIDINES AS SYK MODULATORS

EP4 RECEPTOR AGONIST, COMPOSITIONS AND METHODS THEREOF

N-substituted benzamides and methods of use thereof

N-substituted benzamides and methods of use thereof

N-alkoxyamide conjugates as imaging agents

THIAZOLIDINE DERIVATIVES AND THEIR THERAPEUTIC USE

Monocyclic Heteroaryl Cycloalkyldiamine Derivatives

Modulators of calcium release-activated calcium channel

N-(hetero)aryl, 2-(hetero)aryl-substituted acetamides for use as WNT signaling modulators

Cyclohexyl-azetidinyl antagonists of CCR2

Compositions and methods for inhibition of the JAK pathway

Compounds and compositions as kinase inhibitors

METHODS AND COMPOSITIONS FOR THE TREATMENT OF NECROTIZING ENTEROCOLITIS

Hybrid molecules containing pharmacophores of fluconazole as antifungal agents and their preparation

Compounds

HCV Protease Inhibitors and Uses Thereof

4-tolyl-ethynyl-octahydro-indole-1-ester derivatives

Fused heterocyclic derivatives and methods of use

Kappa opioid receptor agonists

Carbazole-containing sulfonamides as cryptochrome modulators

Quinoxalines and AZA-quinoxalines as CRTHreceptor modulators

Compounds useful for the treatment of metabolic and inflammatory diseases

TGR5 agonists

DEUTERATED 5-HT1A RECEPTOR AGONISTS

Triazole compounds that modulate HSP90 activity

3,5-diaminopyrazole kinase inhibitors

7-MEMBERED RING COMPOUND AND METHOD OF PRODUCTION AND PHARMACEUTICAL APPLICATION THEREOF

Glucagon receptor modulators

Isoindolinone derivatives

Hedgehog pathway modulators

SUBSTITUTED HETEROCYLIC COMPOUNDS

Serotonin reuptake inhibitors

Pyrrolidinones as MetAP-2 inhibitors

Aminopyrrolidinone Derivatives and Uses Thereof

N-arylaminomethylene benzothiophenones for treatment of cardiovascular disease

Piperazinyl methyl phenyl cyclohexane compound

Quinazoline compounds as sodium channel blockers

Substituted quinoxalines and uses thereof

PYRAZOLE-SUBSTITUTED ARYLAMIDES AS P2X3 AND P2X2/3 ANTAGONISTS

Emissive aryl-heteroaryl compounds

Inhibitors of C-FMS kinase

PYRAZOLE DERIVATIVE

Spirocyclic heterocycles medicaments containing said compounds, use thereof and method for their production

Anti-cancer serine hydrolase inhibitory carbamates

Isoindolone derivatives

2,4-DIAMINO-PYRIMIDINES AS AURORA INHIBITORS

TREATMENT OF DISEASES BY EPIGENETIC REGULATION

TREATMENT OF DISEASES BY EPIGENETIC REGULATION

Process and intermediates for preparing macrolactams

Chemical compounds

Crystalline forms of 5-chloro-N2-(2-isopropoxy-5-methyl-4-piperidin-4-yl-phenyl)-N4-[2-(propane-2-sulfonyl)-phenyl]-pyrimidine-2, 4-diamine

Compounds for the treatment of neurodegenerative diseases

QUINAZOLINE DERIVATIVES AS KINASE INHIBITORS

3,5-diaminopyrazole kinase inhibitors

Viral polymerase inhibitors

Viral polymerase inhibitors

METHODS FOR TREATING ATHEROSCLEROSIS

Compound for organic light-emitting diode and organic light-emitting diode including the same

Insecticidal triazines and pyrimidines

Benzyloxypyrimidine derivative, agricultural/ horticultural insecticide comprising derivative and method for using same

Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases

HETEROCYCLIC COMPOUNDS AND THEIR USES

Heterocyclic compounds and their uses

Heterocyclic compounds and uses thereof

Indole and indazole compounds that activate AMPK

Pyrimidine compounds as inhibitors of protein kinases IKK epsilon and/or TBK-1, processes for their preparation, and pharmaceutical compositions containing them

Tetrazine-trans-cyclooctene ligation for the rapid construction of radionuclide labeled probes

Pyridazinyl derivatives as SMO inhibitors

Use of a quinazoline compound in preparing a medicament against flaviviridae virus

Anti-cancer agents

Inhibition of memapsin 1 cleavage in the treatment of diabetes

Quinazoline carboxamide azetidines

Process for the preparation of pazopanib using novel intermediate

Amide compounds

Indazole, benzisoxazole, and benzisothiazole kinase inhibitors

JAK kinase modulating compounds and methods of use thereof

Carbamate and urea inhibitors of 11-beta-hydroxysteroid dehydrogenase 1

Substituted pyrrolidine-2-carboxamides

HETEROCYCLIC COMPOUNDS AND METHODS OF USE

Carboxylic acid amides, the preparation thereof and their use as medicaments

Compounds and method for treatment of cancer

Substituted pyrimidinyl-amines as protein kinase inhibitors

Amino pyrimidine anticancer compounds

Quinazoline derivatives and quinazoline complex protein kinase inhibitor for inhibiting multiplication of tumor cells and preparation method thereof

Preparation of crystalline bazedoxifene and its salts

INDOLES AND THEIR THERAPEUTIC USE

2-CYCLOQUINAZOLINE DERIVATIVES AND METHODS OF USE THEREOF

4-AZOLYLAMINOQUINAZOLINE DERIVATIVES AND METHODS OF USE THEREOF

N-hetarylmethyl pyrazolylcarboxamides

Substituted [1,2,4]triazolo[4,3-A]pyrazines for medicaments and pharmaceutical compositions

Compound for increasing kinase active and application thereof

2-(benzyloxy) benzamides as LRRK2 kinase inhibitors

7-CYCLYLQUINAZOLINE DERIVATIVES AND METHODS OF USE THEREOF

Substituted phthalazin-1(2H)-ones, preparation processes and medical uses thereof

Cyclic amine azaheterocyclic carboxamides

PYRAZOLE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO

4,6-disubstituted pyrimidines useful as kinase inhibitors

Compounds for modulating RNA binding proteins and uses therefor

Quinoxalines derivatives and pharmaceutical compositions and kits

Metal complexes of poly(carboxyl)amine-containing ligands having an affinity for carbonic anhydrase IX

Methods and compositions for protein labelling

7-AZA-SPIRO[3,5]NONANE-7-CARBOXYLATE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF

Method for stereoselective synthesis of bicyclic heterocyclic compounds

SUBSTITUTED HETEROCYCLES AS THERAPEUTIC AGENTS FOR TREATING CANCER

Method for preparing substituted N-(3-amino-quinoxalin-2-yl)-sulfonamides and their intermediates N-(3-chloro-quinoxalin-2-yl)-sulfonamides

Molecules having combinable groups

Melam granulate material and process for preparation thereof

Isoindoline derivatives, pharmaceutical compositions containing them, and their use in therapy

Compounds and their use as BACE inhibitors

Cycloalkyl substituted pyrimidinediamine compounds and their uses

Vitamin E conjugates, and their uses as antioxidants and prodrug delivery vehicles

Ionic Viscoelastics and Viscoelastic Salts

Polymorphs of brimonidine pamoate

Compounds for the treatment of hepatitis C

N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors

INTEGRIN ANTAGONIST CONJUGATES FOR TARGETED DELIVERY TO CELLS EXPRESSING LFA-1

Heterocyclic alkynyl benzene compounds and medical compositions and uses thereof

Alkoxy-substituted 2-aminopyridines as ALK inhibitors

Magnetic media and magnetic recording devices using fluorine compounds

Dual inhibitors of farnesyltransferase and geranylgeranyltransferase I

Pro-neurogenic compounds

Heterocyclic compounds and uses as anticancer agents

PHTHALAZINONE AND RELATED ANALOGS AS SIRTUIN MODULATORS

Modulators of amyloid beta

Substituted pyridazine carboxamide compounds

X-ray and gamma-photon activable organic compounds, their preparation and their uses

Compounds for inhibition of cancer cell proliferation

Glycine transporter inhibiting substances

Small molecule inhibitors of the pleckstrin homology domain and methods for using same

Methods of treating post-traumatic stress disorder using pro-neurogenic compounds

Methods of treating traumatic brain injury using pro-neurogenic compounds

Quinazoline derivatives substituted by aniline, preparation method and use thereof

Indazole compounds and their uses

Adamantyl diamide derivatives and uses of same

Methods for treating Parkinson's disease using pro-neurogenic compounds

Heteroaromatic and aromatic piperazinyl azetidinyl amides as monoacylglycerol lipase inhibitors

Substituted triazoles useful as mGlu5 receptor modulators

Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapy

Pyridazine amide compounds useful as SYK inhibitors

Modulators of ATP-binding cassette transporters

COMPOUNDS FOR THE REDUCTION OF BETA-AMYLOID PRODUCTION

GLP-1 receptor modulators

Nitrogen-containing heteroaryl compounds and methods of use thereof

Small-molecule inhibitors of Rac1 in metastatic breast cancer

Benzimidazole derivatives as selective blockers of persistent sodium current

2,3-DIARYL- OR HETEROARYL-SUBSTITUTED 1,1,1-TRIFLUORO-2-HYDROXYPROPYL COMPOUNDS

Substituted N- [1-cyano-2- (phenyl) ethyl] -2-azabicyclo [2.2.1] heptane-3-carboxamide inhibitors of cathepsin C

Triazine derivative and pharmaceutical composition having an analgesic activity comprising the same

Azetidine derivatives, pharmaceutical compositions and uses thereof

Azetidine derivatives

Substituted Heteroaryls

Pyridinyl amides as P2X3 and P2X2/3 inhibitors

JAK1 Inhibitors

Inhibitors of syk and JAK protein kinases

Substituted benzimidazoles and benzopyrazoles as CCR(4) antagonists

Cannabinoid receptor modulators

Quinoline or quinazoline derivatives with apoptosis inducing activity on cells

1,4-SUBSTITUTED PIPERAZINE DERIVATIVES AND METHODS OF USE THEREOF

Aminopyrimidine derivatives as LRRK2 modulators

Compounds

Aminopyrimidine derivatives as LRRK2 modulators

Aminopyrimidine derivatives as LRRK2 modulators

Pyrimidine derivatives as FAK inhibitors

Azetidine derivatives

Substituted pyrazines and their use in the treatment of disease

Fluorine-18 and carbon-11 labeled radioligands for positron emission tomography (PET) imaging for LRRK2

Hypoglycemic compounds

Benzotriazine oxides as drugs targeting

THERAMUTEIN MODULATORS

Acyl piperazine derivatives as TTX-S blockers

Compounds

2,4-pyrimidinediamine compounds and their uses

Kinase inhibitors

Bicyclic aryl and heteroaryl sodium channel inhibitors

Autotaxin inhibitors and uses thereof

Piperazine derivatives and methods of use

N-cyclopropyl-N-piperidinyl-amide derivatives, pharmaceutical compositions and uses thereof

MODULATORS FOR AMYLOID BETA

Pyrimidyl cyclopentanes as Akt protein kinase inhibitors

Guanidine compound

Compositions and methods for inhibition of the JAK pathway

Organic light-emitting diode including multi-layered hole transporting layer, and flat display device including the organic light-emitting diode

Methods and compositions for kinase inhibition

N-aryl-piperazine derivatives and their use as positive allosteric modulators of mGluR5 receptors

BENZENE, PYRIDINE, AND PYRIDAZINE DERIVATIVES

Functionally selective ligands of dopamine Dreceptors

Bicyclic azaheterocyclic carboxamides

Inhibitors of JAK

Gonadotropin releasing hormone receptor antagonist, preparation method thereof and pharmaceutical composition comprising the same

Pyridine derivatives useful as kinase inhibitors

TRYPTOPHAN HYDROXYLASE INHIBITORS FOR THE TREATMENT OF METASTATIC BONE DISEASE

Tricarbonyl complexes with tridentate chelators for myocardium imaging

N-substituted aminobenzocycloheptene, aminotetraline, aminoindane and phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy

PYRIDONE GLUCOKINASE ACTIVATORS

PYRIDONE AND PYRIDAZONE ANALOGUES AS GPR119 MODULATORS

Substituted pyridazines as EGFR and/or KRAS inhibitors

METHOD FOR TREATING OPHTHALMIC DISEASES USING KINASE INHIBITOR COMPOUNDS IN PRODRUG FORMS

Pharmacokinetically improved compounds

Substituted pyrazine-2-carboxamide kinase inhibitors

Compositions and methods for treating cancer

Tricarbonyl complexes with tridentate chelators for myocardium imaging

BICYCLO-SUBSTITUTED PYRAZOLON AZO DERIVATIVES, PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF

Process for the synthesis of substituted urea compounds

Organogel compositions comprising alkylated benzimidazolones

Substituted imidazolones, compositions containing such compounds and methods of use

Heterocyclic compounds useful for kinase inhibition

Compositions and Methods for Inhibition of TBL-1 Binding to Disease-Associated Molecules

Methods

DIAMINE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE

2-thiopyrimidinones

Substituted pyridazines for controlling invertebrate pests

NOVEL PROCESS FOR THE PREPARATION OF ACYLGUANIDINES AND ACYLTHIOUREAS

Quinazoline-based T cell proliferation inhibitors

6-amino-pyrimidine-4-carboxamide derivatives and related compounds which bind to the sphingosine 1-phosphate (S1P) receptor for the treatment of multiple sclerosis

Quinazoline-2,4-dione derivative, and medical compositions for the prophylaxis and treatment of cranial nerve disease containing the same

Ureido-pyrazole derivatives for use in the treatment of respiratory syncitial virus (RSV) infection

NOVEL CYCLOPROPANE INDOLINONE DERIVATIVES

Azetidinyl diamides as monoacylglycerol lipase inhibitors

Alkoxyimino derivative and pest control agent

Materials for organic electroluminescent devices

Pyrazole compounds useful as protein kinase inhibitors

Antimicrobial compounds and methods of making and using the same

Compound for organic photoelectric device and organic photoelectric device including the same

Pyrazole compound and pharmaceutical use thereof

Pyrazole compounds

Cationic 6-aminoindolines, dyeing compositions containing them, processes and uses thereof

REGIOSELECTIVE PREPARATION OF SUBSTITUTED PYRIMIDINES

5-AMINO-3,6-DIHYDRO-1H-PYRAZIN-2-ONE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE)