95387 ⎘
Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both Nitrogen atom
Sub-classes:PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED
#2NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF
#3HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38
#4COMPOUND USED AS INHIBITOR OF CDK4 KINASE AND USE THEREOF
#5HETEROCYCLIC COMPOUND CCR4 INHIBITOR AND USER THEREOF
#6NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF
#7BICYCLIC HETEROCYCLES AS MRGPRX2 ANTAGONISTS
#8COMPOUNDS, COMPOSITIONS, AND METHODS
#9BICYCLIC HETEROARENES AND METHODS OF THEIR USE
#10SUBSTITUTED PURINES AS TLR7 AGONISTS
#114-SUBSTITUTED AMINOISOQUINOLINE DERIVATIVES
#12CYCLIC DINUCLEOTIDES AS AGONISTS OF STIMULATOR OF INTERFERON GENE DEPENDENT SIGNALLING
#13CRYSTAL FORM OF IMIDAZOLINONE DERIVATIVE
#14HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38
#15COMPOUNDS THAT INHIBIT PI3K ISOFORM ALPHA AND METHODS FOR TREATING CANCER
#16IDH MUTANT INHIBITOR AND USE THEREOF
#17PURINONE COMPOUNDS AND THEIR USE IN TREATING CANCER
#18HPK1 INHIBITORS AND USES THEREOF
#19Heterobicyclic amides as inhibitors of CD38
#20GLP-1R MODULATING COMPOUNDS
#21NOVEL INHIBITORS OF PIKFYVE AND METHODS USING SAME
#22TREX1 INHIBITORS AND USES THEREOF
#23Development of potential antidotes for arsenicals
#24IMIDAZOLIDINONE DERIVATIVES AND MEDICAL USE THEREOF
#25SUBSTITUTED AMINOPURINE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
#26SALT OF ARYLAMINOPURINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF
#27STABILIZATION OF MHC COMPLEXES
#28PROCESSES AND INTERMEDIATES FOR PREPARING A BTK INHIBITOR
#29Photoactive fluorophores and methods of in vivo labeling
#30Certain chemical entities, compositions, and methods
#31PURINE DERIVATIVE AND MEDICAL USE THEREOF
#32HPK1 INHIBITORS AND USES THEREOF
#33Cyclic dinucleotides as agonists of stimulator of interferon gene dependent signalling
#34Substituted purines as TLR7 agonists
#35Cyclic dinucleotides as agonists of stimulator of interferon gene dependent signalling
#36AMINE-SUBSTITUTED ARYL OR HETEROARYL COMPOUNDS
#374-SUBSTITUTED AMINOISOQUINOLINE DERIVATIVES
#38Purinone compounds and their use in treating cancer
#39CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS
#40Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith
#41Heterocyclic compounds and uses as anticancer agents
#42TYK2 inhibitors and uses thereof
#43Heterobicyclic amides as inhibitors of CD38
#44Dual CLK/CDK1 inhibitors for cancer treatment
#45Animal and human anti-malarial agents
#46Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith
#47Certain chemical entities, compositions, and methods
#48Inhibitors of human phosphatidylinositol 3-kinase delta
#49PROCESSES AND INTERMEDIATES FOR PREPARING A BTK INHIBITOR
#50Animal and human anti-malarial agents
#51Substituted purines as TLR7 agonists
#52Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith
#53Dual CLK/CDK1 inhibitors for cancer treatment
#54Heterocyclic amide compound
#55Triazolopyrazine
#56Carbocyclic nucleoside reverse transcriptase inhibitors
#574-substituted aminoisoquinoline derivatives
#58Processes for the preparation of cis-4-[2-{[(3S,4R)-3-fluorooxan-4-yl]amino}-8-(2,4,6-trichloroanilino)-9H-purin-9-yl]-1-methylcyclohexane-1-carboxamide
#59Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith
#60Solid forms of (1S,4S)-4-(2-(((3S,4R)-3-fluorotetrahydro-2H-pyran-4-yl)amino)-8-((2,4,6-trichlorophenyl)amino)-9H-purin-9-yl)-1-methylcyclohexane-1-carboxamide and methods of their use
#61Inhibitors of human phosphatidylinositol 3-kinase delta
#62Preparation and use of kinase inhibitor
#63FUSED IMIDAZOLE COMPOUNDS
#64Animal and human anti-trypanosomonal and anti-leishmania agents
#65Animal and human anti-malarial agents
#66FUSED PYRIMIDINE-BASED HYDROXAMATE DERIVATIVES
#67TYK2 inhibitors and uses thereof
#68Preparation and use of kinase inhibitor
#69Certain chemical entities, compositions, and methods
#70Heterocyclic compounds and use thereof
#71AMINE-SUBSTITUTED ARYL OR HETEROARYL COMPOUNDS
#72Animal and human anti-malarial agents
#73Animal and human anti-trypanosomonal and anti-leishmania agents
#74Inhibitors of human phosphatidylinositol 3-kinase delta
#75Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith
#76Solid forms of (1S,4S)-4-(2-(((3S,4R)-3-fluorotetrahydro-2H-pyran-4-yl)amino)-8-((2,4,6-trichlorophenyl)amino)-9H-purin-9-yl)-1-methylcyclohexane-1-carboxamide and methods of their use
#77Pyrrolopyrimidine compounds as inhibitors of protein kinases
#78PYRIMIDINE SUBSTITUTED PURINE COMPOUNDS AS KINASE (S) INHIBITORS
#79Fused pyrimidine-based hydroxamate derivatives
#80Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith
#81Fused imidazole compounds
#82Certain chemical entities, compositions, and methods
#83Purine derivatives as modulators of TNF activity
#84FATTY ACID ANTIVIRAL CONJUGATES AND THEIR USES
#85Substituted [1,2,4]triazolo[4,3-a]pyrazines as BRD4 inhibitors
#86Substituted aminopurine compounds, compositions thereof, and methods of treatment therewith
#87Heterocyclic compounds and use thereof
#88Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith
#89Chemical compounds, compositions and methods for kinase modulation
#90Imidazopyrimidine derivatives
#91Inhibitors of bruton's tyrosine kinase
#92N-(1-(substituted-phenyl)ethyl)-9H-purin-6-amines as PI3K inhibitors
#93Wee1 degradation inhibitors
#94Pyridinones
#95N-aryl unsaturated fused ring tertiary amine compounds, preparation method and anti-tumor applications thereof
#96Pyrimidine substituted purine compounds as kinase (S) inhibitors
#97Paralytic shellfish poison
#98Thiazolopyrimidine modulators as immunosuppressive agents
#99Chemical Compounds - 759
#100SUBSTITUTED PIPERAZINYL-PYRROLIDINE COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS
#101Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK)
#102Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith
#103Chemical Compounds - 759
#104Inhibitors of human phosphatidylinositol 3-kinase delta
#105Substituted [1,2,4]triazolo[4,3-A]pyrazines that are BRD4 inhibitors
#106Immune system modulators
#107Chemical compounds, compositions and methods for kinase modulation
#108Anti-cancer activity of novel bicyclic heterocycles
#109PYRIMIDINE SUBSTITUTED PURINE DERIVATIVES
#110WNT PATHWAY ANTAGONISTS
#111Cyclopropanecarboxylate esters of purine analogues
#112Indolin-2-one derivatives as protein kinase inhibitors
#113HALOARYL SUBSTITUTED AMINOPURINES, COMPOSITIONS THEREOF,AND METHODS OF TREATMENT THEREWITH
#114Arylamino purine derivatives, preparation method and pharmaceutical use thereof
#115Heterocyclic compounds and uses as anticancer agents
#116Pyrimidine substituted purine derivatives
#117ISOTOPOLOGUES OF 4-[9-(TETRAHYDRO-FURAN-3-YL)-8-(2,4,6-TRIFLUORO-PHENYLAMINO)-9H-PURIN-2-YLAMINO]-CYCLOHEXAN-1-OL
#118Method for assaying histone methylation enzyme activity
#119Artificial fluorescent bases
#120Heterocyclic compounds and methods of use
#121Inhibitors of human phosphatidylinositol 3-kinase delta
#122N-(1-(substituted-phenyl)ethyl)-9H-purin-6-amines as PI3K inhibitors
#123Pyrimidine substituted purine compounds as kinase (S) inhibitors
#124Inhibitors of human phosphatidylinositol 3-kinase delta
#125Purine PI3K inhibitor compounds and methods of use
#126CHEMICAL COMPOUNDS
#127Chemical compounds, compositions and methods for kinase modulation
#128Thiazolopyrimidine modulators as immunosuppressive agents
#129Purine compounds selective for PI3K P110 delta, and methods of use
#130Antithrombotic diadenosine tetraphosphates and related analogs
#131Substituted piperazinyl-pyrrolidine compounds useful as chemokine receptor antagonists
#1328-HETEROARYLPURINE MNK2 INHIBITORS FOR TREATING METABOLIC DISORDERS
#133Methods of treatment using heteroaryl compounds and compositions thereof
#134STABILIZED SOLID DISPERSION OF ADEFOVIR DIPIVOXIL AND PREPARATION METHOD THEREOF
#135PI3K isoform selective inhibitors
#136PYRAZINE SUBSTITUTED PURINES
#137PURINES AS PKC-THETA INHIBITORS
#1382-MORPHOLINYLPURINES AS INHIBITORS OF PI3K
#1399-(pyrazol-3-yl)-9H-purine-2-amine and 3-(pyrazol-3-yl) -3H-imidazo[4,5-B] pyridin-5-amine derivatives and their use for the treatment of cancer
#140Pyrimidine substituted purine derivatives
#141Methods of modulating inflammatory cell recruitment and gene expression using haloaryl substituted aminopurines
#142BICYCLIC HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE
#143Convertible nucleoside derivatives
#144Inhibitors of human phosphatidylinositol 3-kinase delta
#145Inhibitors of human phosphatidylinositol 3-kinase delta
#146PROCESS FOR PREPARING PURINE DERIVATIVE
#147Azacycloalkane Derivatives as Inhibitors of Stearoyl-Coenzyme a Delta-9 Desaturase
#148Purine PI3K inhibitor compounds and methods of use
#149METHODS OF TREATMENT COMPRISING THE ADMINISTRATION OF HALOARYL SUBSTITUTED AMINOPURINES OR COMPOSITIONS THEREOF
#150Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith
#151Chemical compounds
#152PHARMACEUTICALLY ACCEPTABLE SALTS AND POLYMORPHIC FORMS
#153Drying process for preparing crystalline solid famciclovir
#1546-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
#155Heteroaryl compounds, compositions thereof, and methods of treatment therewith
#156Purinone derivatives for treating neurodegenerative diseases
#157Purine and imidazopyridine derivatives for immunosuppression
#1586-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
#159Purine derivatives for use as adenosine A-2A receptor agonists
#160Chemical compounds
#161Process for the manufacture of famciclovir using phase-transfer catalysts
#1628-substituted 2-(benzimidazolyl)purine derivatives for immunosuppression
#163Purine, Pyrimidine, and Azaindole Derivatives
#1645-membered annelated heterocyclic pyrimidines as kinase inhibitors
#1658-heteroarylpurine MNK2 inhibitors for treating metabolic disorders
#166Methods of treatment and prevention using haloaryl substituted aminopurines
#167AMINOPURINE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES
#168Purine compounds
#169Process for producing dioxolane nucleoside analogues
#170c-MET modulators and method of use
#171Tyrosine kinase inhibitors
#172Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith
#173Purine and imidazopyridine derivatives for immunosuppression
#174Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith
#175Purine derivatives as purinergic receptor antagonists
#176Preparation of famciclovir and other purine derivatives
#1772-amino-9-(2-substituted ethyl)purines and preparing methods for 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine using the same
#178Substituted piperazinyl-pyrrolidine compounds useful as chemokine receptor antagonists
#179Antiviral methods employing double esters of 2′, 3′-dideoxy-3′-fluoroguanosine
#180Fused 1,3-dihydro-imidazole ring compounds
#181Antiviral methods employing double esters of 2′, 3′-dideoxy-3′-fluoroguanosine
#182Drying process for preparing crystalline solid famciclovir
#183Inhibitors of human phosphatidylinositol 3-kinase delta
#184Purine nucleosides
#185AN IMPROVED PROCESS FOR THE PREPARATION OF PURINES
#186Phenyl substituted imidaopyridines and phenyl substituted benzimidazoles
#187Process for preparing famciclovir
#188Process for producing dioxolane nucleoside analogues