ClassID:

95394

C07D475/04 - CPC Classification

Classification description:

Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Recent Application in this class:
#1
20250368632
2025-12-04

CRYPTOPHYCIN COMPOUNDS AND CONJUGATES THEREOF

#2
20250243161
2025-07-31

DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS

#3
20250230164
2025-07-17

POLYMORPHS OF SEPIAPTERIN AND SALTS THEREOF

#4
20250115604
2025-04-10

SULFOXIMINE GLYCOSIDASE INHIBITORS

#5
20240400574
2024-12-05

NEW STABLE SALT OF 5,10-METHYLENE-(6R)-TETRAHYDROFOLIC ACID

#6
20240252693
2024-08-01

FOLATE RECEPTOR-TARGETED RADIOTHERAPEUTIC AGENTS AND THEIR USE

#7
20240246910
2024-07-25

Delivery of therapeutic alkaloid compounds

#8
20240043426
2024-02-08

Polymorphs of sepiapterin and salts thereof

#9
20230416253
2023-12-28

Folate salts

#10
20230364243
2023-11-16

CANCER-SELECTIVE TARGET DEGRADATION BY TARGETING GROUP CAGED PROTACS

#11
20230159455
2023-05-25

Delivery of therapeutic alkaloid compounds

#12
20230054325
2023-02-23

COMPOSITIONS COMPRISING FOLIC ACID DERIVATIVES, THEIR PREPARATIONS AND METHODS OF USE

#13
20220177470
2022-06-09

Sulfoximine glycosidase inhibitors

#14
20220143027
2022-05-12

Stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid

#15
20220081443
2022-03-17

POLYMORPHIC FORM OF SEPIAPTERIN

#16
20220024940
2022-01-27

Stable salt of 5,10-methylene-(6R)-tetrahydrofolic acid

#17
20210403471
2021-12-30

Folate salts

#18
20210300930
2021-09-30

Polymorphs of sepiapterin and salts thereof

#19
20210277006
2021-09-09

Crystalline salts of 5-methyl-(6S)-tetrahydrofolic acid and amino ethyl esters

#20
20210269444
2021-09-02

Crystalline salt of 5-methyl-(6S)-tetrahydrofolic acid and L-isoleucine ethyl ester

#21
20210269443
2021-09-02

PHARMACEUTICALLY ACCEPTABLE SALTS OF SEPIAPTERIN

#22
20210107902
2021-04-15

Crystalline sodium salt of 5-methyl-(6S)-tetrahydrofolic acid

#23
20210061764
2021-03-04

BIVALENT LINKERS AND CONJUGATES THEREOF

#24
20210002281
2021-01-07

Compositions comprising folic acid derivatives, their preparations and methods of use

#25
20200297765
2020-09-24

Modified immune cells and uses thereof

#26
20200283443
2020-09-10

Stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid

#27
20200247807
2020-08-06

Folate derivatives, useful in particular in the context of the folate assay

#28
20200124521
2020-04-23

FLUORESCENT PROBE FOR FLOW CYTOMETRY, AND METHOD FOR SCREENING FLUORESCENCE-LABELED CELLS

#29
20200039982
2020-02-06

Crystalline binary sodium salts of 5-methyl-(6S)-tetrahydrofolic acid with organic bases

#30
20200010469
2020-01-09

Polymorphic form of sepiapterin

#31
20200009145
2020-01-09

Medicinal agent and beverage/food for preventing cerebral dysfunction and improving same

#32
20200002326
2020-01-02

Sulfoximine glycosidase inhibitors

#33
20190388427
2019-12-26

Stable 5-methyltetrahydrofolate formulations to moderate methylenetetrahydrofolate reductase associated polymorphisms

#34
20190388415
2019-12-26

Substituted dihydrobenzofuran glycosidase inhibitors

#35
20190359682
2019-11-28

INHIBITORS OF THE FIBROBLAST GROWTH FACTOR RECEPTOR

#36
20190315749
2019-10-17

Compositions comprising folic acid derivatives, their preparations and methods of use

#37
20190308975
2019-10-10

Polymorphs of sepiapterin and salts thereof

#38
20190300482
2019-10-03

Bivalent linkers and conjugates thereof

#39
20190298721
2019-10-03

STABLE PRO-VITAMIN DERIVATIVE COMPOUNDS, PHARMACEUTICAL AND DIETARY COMPOSITIONS, AND METHODS OF THEIR USE

#40
20190270745
2019-09-05

Stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid

#41
20190241605
2019-08-08

HPPK inhibitors useful as antibacterial agents

#42
20190175572
2019-06-13

Bis-benzylidine piperidone proteasome inhibitor with anticancer activity

#43
20190152974
2019-05-23

SUBSTITUTED PTERIDINES USEFUL FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTIONS

#44
20190106431
2019-04-11

NEW STABLE SALT OF 5,10-METHYLENE-(6R)-TETRAHYDROFOLIC ACID

#45
20190100494
2019-04-04

BIVALENT LINKERS AND CONJUGATES THEROF

#46
20190048011
2019-02-14

Compositions comprising folic acid derivatives, their preparations and methods of use

#47
20180362613
2018-12-20

Inhibitors of the fibroblast growth factor receptor

#48
20180362456
2018-12-20

NEW COMPOUNDS WITH ANTIOXIDANT AND ANTIAGING ACTIVITY

#49
20180280522
2018-10-04

Folate-conjugated molecules for delivery of toxic small molecule inhibitors to cancer cells and methods of use

#50
20180258099
2018-09-13

Labeled chemically reactive and biologically active conjugates, and methods and compositions thereof

#51
20180170934
2018-06-21

Folate derivatives, useful in particular in the context of the folate assay

#52
20180134711
2018-05-17

Stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid

#53
20180133334
2018-05-17

Targeting aminoacid lipids

#54
20180078557
2018-03-22

MEDICINAL AGENT AND BEVERAGE/FOOD FOR PREVENTING CEREBRAL DYSFUNCTION AND IMPROVIDNG SAME

#55
20180072734
2018-03-15

F-labelled folates as PET radiotracers

#56
20180000823
2018-01-04

Stable 5-methyltetrahydrofolate formulations to moderate methylenetetrahydrofolate reductase associated polymorphisms

#57
20170320826
2017-11-09

BIVALENT LINKERS AND CONJUGATES THEREOF

#58
20170283442
2017-10-05

Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules

#59
20170281800
2017-10-05

Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors

#60
20170273984
2017-09-28

Solid solution comprising (6S)-5-methyl tetrahydrofolic acid or salt thereof, and preparation and use thereof

#61
20170129893
2017-05-11

Novel Crystalline Form of Levomefolate

#62
20170128599
2017-05-11

FOLATE-CONJUGATES AND CORRESPONDING METAL-CHELATE COMPLEXES FOR USE IN DIAGNOSTIC IMAGING AND RADIOTHERAPY

#63
20170121333
2017-05-04

Compositions comprising folic acid derivatives, their preparations and methods of use

#64
20170066812
2017-03-09

INHIBITORS OF THE FIBROBLAST GROWTH FACTOR RECEPTOR

#65
20160339122
2016-11-24

Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors

#66
20160229814
2016-08-11

Heterocyclic compound

#67
20160207925
2016-07-21

L-METHYLFOLATE SALT PREPARATIONS, MEDICAMENTS, AND NUTRITIONAL SUPPLEMENTS COMPRISING SUCH SALTS THEREOF

#68
20160207890
2016-07-21

ETHYNYL DERIVATIVES

#69
20160159802
2016-06-09

F-labelled folates

#70
20160106725
2016-04-21

Bis-benzylidine piperidone proteasome inhibitor with anticancer activity

#71
20160011199
2016-01-14

Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors

#72
20160002167
2016-01-07

Bivalent linkers and conjugates thereof

#73
20150361090
2015-12-17

Labeled chemically reactive and biologically active comjugates, and methods and compositions thereof

#74
20150355201
2015-12-10

Folate derivatives, useful in particular in the context of the folate assay

#75
20150315189
2015-11-05

F-labelled folates

#76
20150307524
2015-10-29

Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules

#77
20150291590
2015-10-15

COMPOSITIONS AND METHODS FOR THE TREATMENT OF METABOLIC DISEASES

#78
20150218167
2015-08-06

Linked purine pterin HPPK inhibitors useful as antibacterial agents

#79
20150210695
2015-07-30

Compositions comprising folic acid derivatives, their preparations and methods of use

#80
20150203497
2015-07-23

Composition, synthesis, and use of new substituted pyran and pterin compounds

#81
20150166542
2015-06-18

Immunological reagents and uses therefor

#82
20150166465
2015-06-18

Lipid formulations

#83
20150152110
2015-06-04

Stable complexes of an alkaline earth metal salt of N-methyl-tetrahydrofolic acid and a polyol

#84
20150125390
2015-05-07

18F-labelled folate/antifolate analogues

#85
20150119574
2015-04-30

Method for producing sepiapterin and tetrahydrolactoylpterin

#86
20150119573
2015-04-30

Method for synthesizing sapropterin dihydrochloride

#87
20150105555
2015-04-16

Method for synthesizing sapropterin dihydrochloride

#88
20150099000
2015-04-09

Polyamine derivatives

#89
20150065708
2015-03-05

Compound JK12A and preparation thereof

#90
20150030669
2015-01-29

Targeting aminoacid lipids

#91
20150018357
2015-01-15

Crystal form of (6S)-5-methyltetrahydrofolate salt and method for preparing same

#92
20140315853
2014-10-23

Methods, formulations, and kits for rapidly repleting folate levels in women

#93
20140234216
2014-08-21

Folate conjugates of albumin-binding entities

#94
20140121371
2014-05-01

PROCESSES AND REAGENTS FOR MAKING DIARYLIODONIUM SALTS

#95
20140121361
2014-05-01

NSchelator-folate derivatives, preparation method thereof and composition for diagnosis or treatment of cancer containing the same as an active ingredient

#96
20140112866
2014-04-24

Positron emission tomography imaging method

#97
20140050775
2014-02-20

Polyamine derivatives

#98
20130310390
2013-11-21

Composition, synthesis, and use of new substituted pyran and pterin compounds

#99
20130251809
2013-09-26

Polyamine derivatives

#100
20130197222
2013-08-01

Preparation process of (6R)-tetrahydrobiopterin hydrochloride

#101
20130172285
2013-07-04

Linked purine pterin HPPK inhibitors useful as antibacterial agents

#102
20130171074
2013-07-04

TARGETING COMPOUNDS

#103
20130158271
2013-06-20

Bivalent linkers and conjugates thereof

#104
20130144045
2013-06-06

Self-reactive arms and prodrugs comprising same

#105
20130090474
2013-04-11

Process for the preparation of pteridine derivatives

#106
20130040956
2013-02-14

Process for the preparation of stable, amorphous calcium salt of (6S)-N(5)-methyl-5,6,7,8-tetrahydrofolic acid

#107
20120329803
2012-12-27

Dihydropteridinones, method for production and use thereof

#108
20120315679
2012-12-13

Synthesis of (6S)-5,6,7,8-tetrahydrofolic acid

#109
20120270791
2012-10-25

Methods and compositions for treating and diagnosing kidney disease

#110
20120245177
2012-09-27

Crystalline levofolinic acid and process for its preparation

#111
20120245168
2012-09-27

Composition, synthesis, and use of new substituted pyran and pterin compounds

#112
20120183602
2012-07-19

Lipid formulation

#113
20120115244
2012-05-10

MATERIALS AND METHODS FOR IMMUNOASSAY OF PTERINS

#114
20120077792
2012-03-29

Lanthanide metal complexes useful in treating cancer

#115
20120022072
2012-01-26

PTERIN ANALOGS

#116
20110288090
2011-11-24

Inhibitors of AKT Activity

#117
20110286921
2011-11-24

18F-LABELLED FOLATES AS PET RADIOTRACERS

#118
20110218339
2011-09-08

Crystalline polymorph of biopterin and production method thereof

#119
20110212942
2011-09-01

Inhibitors of polo-like kinase

#120
20110207716
2011-08-25

Inhibitors of polo-like kinase

#121
20110207164
2011-08-25

Method for assessment of folate phenotypes, disease risk and response to therapy

#122
20110065714
2011-03-17

SUBSTITUTED QUINAZOLINES

#123
20110028714
2011-02-03

Folate mimetics and folate-receptor binding conjugates thereof

#124
20100324120
2010-12-23

Lipid formulation

#125
20100322854
2010-12-23

Positron emission tomography imaging method

#126
20100305117
2010-12-02

Substituted pteridines useful for the treatment and prevention of viral infections

#127
20100260817
2010-10-14

Polyamine derivatives

#128
20100249141
2010-09-30

Inhibitors of folic acid-dependent enzymes

#129
20100240667
2010-09-23

Process for preparing crystalline polymorphic forms of (6R)-L-erythro-tetrahydrobiopterin dihydrochloride

#130
20100234385
2010-09-16

Compsition Containing Biopterin and Method for Using The Same

#131
20100209347
2010-08-19

Cyclodextrin compound modified with folic acid, process for production thereof, drug delivery agent for targeting drug delivery system, pharmaceutical composition, and imaging agent

#132
20100168117
2010-07-01

Stable, crystalline (6S)-N(5)-methyl-5,6,7,8,-tetrahydrofolic acid

#133
20100151533
2010-06-17

Synthesis of (6S)-5methyl-5,6,7,8-tetrahydrofolic acid

#134
20100143249
2010-06-10

FOLATE-CONJUGATES AND CORRESPONDING METAL-CHELATE COMPLEXES FOR USE IN DIAGNOSTIC IMAGING AND RADIOTHERAPY

#135
20100111864
2010-05-06

18F-LABELLED FOLATES

#136
20100111863
2010-05-06

F-labelled folates

#137
20100105692
2010-04-29

Dipterinyl Calcium Pentahydrate (DCP) and Therapeutic Methods Based Thereon

#138
20100104626
2010-04-29

METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING KIDNEY DISEASE

#139
20100099685
2010-04-22

Crystalline forms of (6R)-L-erythro-tetrahydrobiopterin dihydrochloride

#140
20100056533
2010-03-04

18F-labelled folates

#141
20100016328
2010-01-21

PTERIN ANALOGS

#142
20090318456
2009-12-24

SUBSTITUTED PTERIDINES FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTIONS

#143
20090281083
2009-11-12

Combination Product

#144
20090270619
2009-10-29

Method for producing alpha form crystals of sapropterin hydrochloride

#145
20090227539
2009-09-10

Boron compounds useful in BNCT

#146
20090209543
2009-08-20

Folates, compositions and uses thereof

#147
20090203889
2009-08-13

Bivalent linkers and conjugates thereof

#148
20080306263
2008-12-11

Process For The Preparation Of Optically Pure Tetrahydropterins And Derivatives, And Specifically Of Optically Pure Tetrahydrofolic Acid And Derivatives Thereof, By Stereospecific Hydrogenation

#149
20080214550
2008-09-04

Inhibitors of folic acid-dependent enzymes

#150
20080207652
2008-08-28

Novel inhibitors of folic acid-dependent enzymes

#151
20080188423
2008-08-07

PI-3 kinase inhibitor prodrugs

#152
20080166355
2008-07-10

Dipterinyl calcium pentahydrate (DCP) and therapeutic methods based thereon

#153
20080153849
2008-06-26

Process for the Preparation of Crystalline (6Rrs)-N(5)-Formyl-5,6,7,8-Tetrahydrofolic Acid

#154
20070265444
2007-11-15

Inhibitors of folic acid-dependent enzymes

#155
20070244322
2007-10-18

Process for preparing tetrahydrobiopterin and analogs of tetrahydrobiopterin

#156
20070190596
2007-08-16

Synthesis of (6S)-5-methyl-5,6,7,8-tetrahydrofolic acid

#157
20070155752
2007-07-05

2-Amino-o4-substituted pteridines and their use as inactivators of o6-alkylguanine-dna alkyltransferase

#158
20070134729
2007-06-14

Novel antibacterial agents

#159
20070004721
2007-01-04

Pteridine derivatives for the treatment of septic shock and tnf-a-related diseases

#160
20060287314
2006-12-21

Immunosuppressive effects of pteridine derivatives

#161
20060189620
2006-08-24

Immunosuppressive effects of pteridine derivatives

#162
20060173035
2006-08-03

3-aryloxy/thio-2,3-substituted propanamines and their use in inhibiting serotonin and norepinephrine reuptake

#163
20060142573
2006-06-29

Method for producing L-biopterin

#164
20060116388
2006-06-01

CXCR3 antagonists

#165
20060046990
2006-03-02

Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions

#166
20060035901
2006-02-16

Methotrexate derivatives useful for treating cancer and arthritis

#167
20060035900
2006-02-16

Crystalline forms of (6R)-L-erythro-tetrahydrobiopterin dihydrochloride

#168
20060009458
2006-01-12

Methods of treating hypertension

#169
20050227985
2005-10-13

Folate mimetics and folate-receptor binding conjugates thereof

#170
20050203173
2005-09-15

PI-3 kinase inhibitor prodrugs

#171
20050171348
2005-08-04

(6S)-5,6,7,8-tetrahydrofolic acid production process

#172
20050165227
2005-07-28

Vitamin-mitomycin conjugates

#173
18231103
2023-12-19

Antiproliferative selenated-folate hybrids