ClassID:

95424

C07D487/20 - CPC Classification

Classification description:

Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups - in which the condensed system contains three hetero rings Spiro-condensed systems

Recent Application in this class:
#1
20260092071
2026-04-02

COMPOUNDS AND COMPOSITIONS AS SMARCA2/4 DEGRADERS AND USES THEREOF

#2
20250353860
2025-11-20

PIPERIDINE CARBOXAMIDE AZAINDANE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF

#3
20250340560
2025-11-06

SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINES AS BRUTON'S TYROSINE KINASE MODULATORS

#4
20250270226
2025-08-28

SUBSTITUTED 1',2'-DIHYDRO-3'H-SPIRO[CYCLOHEXANE-1,4'-PYRIMIDO[5',4':4,5]PYRROLO[2,1-c][1,2,4]TRIAZIN]-3'-ONES AS CYCLIN-DEPENDENT KINASE INHIBITORS

#5
20250243214
2025-07-31

MORPHIC FORMS OF TRILACICLIB AND METHODS OF MANUFACTURE THEREOF

#6
20250243213
2025-07-31

MORPHIC FORMS OF TRILACICLIB AND METHODS OF MANUFACTURE THEREOF

#7
20250243212
2025-07-31

MORPHIC FORMS OF TRILACICLIB AND METHODS OF MANUFACTURE THEREOF

#8
20250230168
2025-07-17

AZASPIRO WRN INHIBITORS

#9
20250136610
2025-05-01

CRYSTALLINE FORMS OF TRILACICLIB AND TRILACICLIB SALTS

#10
20250101030
2025-03-27

MORPHIC FORMS OF TRILACICLIB AND METHODS OF MANUFACTURE THEREOF

#11
20250059179
2025-02-20

Heterocyclic Compounds and Methods of Use

#12
20250019380
2025-01-16

PI3K-ALPHA INHIBITORS AND METHODS OF USE THEREOF

#13
20250002492
2025-01-02

COMPOSITIONS OF FOLATE ABSORPTION INHIBITORS AND METHODS THEREOF

#14
20240254128
2024-08-01

SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINES AS BRUTON'S TYROSINE KINASE MODULATORS

#15
20240246989
2024-07-25

DISPIROPYRROLIDINE DERIVATIVES

#16
20240199647
2024-06-20

ANTI-VIRAL COMPOUNDS

#17
20240174683
2024-05-30

MAP4K1 INHIBITORS

#18
20240150369
2024-05-09

Substituted 1′,2′-dihydro-3′H-spiro[cyclohexane-1,4′-pyrimido[5′,4′:4,5]pyrrolo[2,1-c][1,2,4]triazin]-3′-ones as cyclin-dependent kinase inhibitors

#19
20240116942
2024-04-11

SELECTIVE CDK 4/6 INHIBITOR CANCER THERAPEUTICS

#20
20240109913
2024-04-04

Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-p53 inhibitors

#21
20240109906
2024-04-04

CDK INHIBITORS

#22
20230374028
2023-11-23

SOLID STATE FORMS OF TRILACICLIB AND OF TRILACICLIB SALTS

#23
20230348482
2023-11-02

TETRAHYDRO-SPIROINDOLINE-PYRROLOPYRROLE-TRIONES INHIBITORS OF THE NRF2-BETA-TRCP INTERACTION FOR USE IN THE TREATMENT OF FATTY LIVER DISEASE

#24
20230227461
2023-07-20

Selective CDK4/6 inhibitor cancer therapeutics

#25
20230139809
2023-05-04

BENZIMIDAZOLE DERIVATIVES

#26
20230055237
2023-02-23

COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS

#27
20230042042
2023-02-09

UNNATURAL AMINO ACIDS AND USES THEREOF

#28
20230013862
2023-01-19

SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINES AS BRUTON'S TYROSINE KINASE MODULATORS

#29
20220370420
2022-11-24

Spirocyclic 2,3-dihydro-7-azaindole compounds and uses thereof

#30
20220306644
2022-09-29

Substituted 1′,2′-dihydro-3′H-spiro[cyclohexane-1,4′-pyrimido[5′,4′:4,5]pyrrolo[2,1-c][1,2,4]triazin]-3′-ones as cyclin-dependent kinase inhibitors

#31
20220106324
2022-04-07

DISPIROPYRROLIDINE DERIVATIVES

#32
20220098211
2022-03-31

SPIRO-LACTAM AND BIS-SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF

#33
20210395259
2021-12-23

CDK INHIBITORS

#34
20210387993
2021-12-16

Morphic forms of trilaciclib and methods of manufacture thereof

#35
20210261552
2021-08-26

ERK inhibitor and use thereof

#36
20210122755
2021-04-29

Synthesis of N-(heteroaryl)-pyrrolo[3,2-d]pyrimidin-2-amines

#37
20210101912
2021-04-08

NEW SPIRO[3H-INDOLE-3,2'-PYRROLIDIN]-2(1H)-ONE COMPOUNDS AND DERIVATIVES AS MDM2-P53 INHIBITORS

#38
20210079007
2021-03-18

MDM2 inhibitors

#39
20210077498
2021-03-18

TRANSIENT PROTECTION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS AGAINST IONIZING RADIATION

#40
20200377519
2020-12-03

Hepatitis B antiviral agents

#41
20200354372
2020-11-12

1,2,3',5'-TETRAHYDRO-2'H-SPIRO[INDOLE-3,1'-PYRROLO[3,4-C]PYRROLE]-2,3'-DIONE COMPOUNDS AS THERAPEUTIC AGENTS ACTIVATING TP53

#42
20200317683
2020-10-08

MTOR inhibitor compounds

#43
20200277300
2020-09-03

CDK inhibitors

#44
20200181159
2020-06-11

Spiro-lactam and bis-spiro-lactam NMDA receptor modulators and uses thereof

#45
20200148690
2020-05-14

Substituted pyrazolo[1,5-a]pyrimidines as Bruton's tyrosine kinase modulators

#46
20200140449
2020-05-07

Spiroindolinones and therapeutic uses thereof

#47
20190169209
2019-06-06

Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-p53 inhibitors

#48
20190167691
2019-06-06

TRANSIENT PROTECTION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS AGAINST IONIZING RADIATION

#49
20190135820
2019-05-09

Synthesis of n-(heteroaryl)-pyrrolo[3,2-d]pyrimidin-2-amines

#50
20190119292
2019-04-25

CDK inhibitors

#51
20190106325
2019-04-11

Metal halide crystals having a nanotube structure and methods

#52
20190055204
2019-02-21

COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF

#53
20180303838
2018-10-25

TRANSIENT PROTECTION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS AGAINST IONIZING RADIATION

#54
20180291030
2018-10-11

NEW SPIRO[3H-INDOLE-3,2'-PYRROLIDIN]-2(1H)-ONE COMPOUNDS AND DERIVATIVES AS MDM2-P53 INHIBITORS

#55
20180251466
2018-09-06

Substituted pyrazolo[1,5-a]pyrimidines as Bruton's tyrosine kinase modulators

#56
20180201619
2018-07-19

CDK inhibitors

#57
20180201618
2018-07-19

CDK inhibitors

#58
20180201617
2018-07-19

CDK inhibitors

#59
20180127431
2018-05-10

Lactam kinase inhibitors

#60
20170334924
2017-11-23

Spirocyclic heterocyclic compounds useful as HIV integrase inhibitors

#61
20170333440
2017-11-23

Tricyclic lactams for use in HSPC-sparing treatments for Rb-positive abnormal cellular proliferation

#62
20170247394
2017-08-31

Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-p53 inhibitors

#63
20170204110
2017-07-20

Compounds and methods for the treatment of cystic fibrosis

#64
20170186977
2017-06-29

Organic electroluminescent materials and devices

#65
20170174690
2017-06-22

Substituted 4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrazine derivatives and 5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a][1,4]diazepine derivatives as Ros1 inhibitors

#66
20170130124
2017-05-11

Pentaarylbiimidazole compound and production method for said compound

#67
20170129903
2017-05-11

COMPOUNDS COMPRISING 1,1a,2,5a-TETRAHYDROSPIRO[INDOLE-3,2a-PYRROLE]-2,5a-DIONE SYSTEM AS INHIBITORS P53-MDM2 PROTEIN-PROTEIN INTERACTION

#68
20170073349
2017-03-16

Substituted pyrazolo[1,5-a]pyrimidines as bruton's tyrosine kinase modulators

#69
20170057972
2017-03-02

Lactam kinase inhibitors

#70
20170057971
2017-03-02

CDK inhibitors

#71
20160368921
2016-12-22

Substituted polycyclic carbamolypyridone derivative

#72
20160311824
2016-10-27

Substituted 4,5,6,7-tetrahydropyrazolo[1,5-A]pyrazine derivatives as casein kinase 1 D/E inhibitors

#73
20160297828
2016-10-13

SPIROCYCLIC COMPOUNDS CONTAINING SPIRO[INDOLYL-3,1'-PYRROLO[3,4-C]PYRROLE] CORE AND SULPHUR-CONTAINING AMINO ACID RESIDUES

#74
20160158201
2016-06-09

Chemical compounds

#75
20160122358
2016-05-05

NOVEL SUBSTITUTED PYRAZOLO-PIPERAZINES AS CASEIN KINASE 1 D/E INHIBITORS

#76
20160108054
2016-04-21

Lactam kinase inhibitors

#77
20160083400
2016-03-24

TRICYCLIC GUANIDINE DERIVATIVE

#78
20160083392
2016-03-24

Substituted imidazo[1,2-b]pyrazoles as bruton'S tyrosine kinase modulators

#79
20160000764
2016-01-07

Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-P53 inhibitors

#80
20150299212
2015-10-22

Tricyclic lactams for use in HSPC-sparing treatments for RB-positive abnormal cellular proliferation

#81
20150291611
2015-10-15

Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-P53 inhibitors

#82
20150259354
2015-09-17

Substituted pyrazolo[1,5-a]pyrimidines as bruton's tyrosine kinase modulators

#83
20150246926
2015-09-03

CDK inhibitors

#84
20150246925
2015-09-03

CDK inhibitors

#85
20140371455
2014-12-18

Chemical compounds

#86
20140350243
2014-11-27

Materials for organic electroluminescent devices

#87
20140349992
2014-11-27

Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof

#88
20140274896
2014-09-18

Transient Protection of Hematopoietic Stem and Progenitor Cells Against Ionizing Radiation

#89
20140249195
2014-09-04

7-azoniabicyclo[2.2.1]heptane derivatives, methods of production, and pharmaceutical uses thereof

#90
20140206661
2014-07-24

Thiadiazole analogs thereof and methods for treating SMN-deficiency-related-conditions

#91
20140121196
2014-05-01

DISPIROPYRROLIDINE DERIVATIVES

#92
20140099681
2014-04-10

Process for producing optically active succinimide derivatives and intermediates thereof

#93
20130237544
2013-09-12

CDK inhibitors

#94
20130237534
2013-09-12

CDK inhibitors

#95
20130237533
2013-09-12

CDK inhibitors

#96
20130196388
2013-08-01

Process for producing optically active succinimide derivatives

#97
20130165424
2013-06-27

Dispiropyrrolidine derivatives

#98
20130109679
2013-05-02

Heterocyclic compounds containing an indole core

#99
20130102775
2013-04-25

Photochromic material

#100
20130059898
2013-03-07

7-azoniabicyclo [2.2.1] heptane derivatives, methods of production, and pharmaceutical uses thereof

#101
20130012700
2013-01-10

Materials for organic electroluminescent devices

#102
20120264738
2012-10-18

DISPIROPYRROLIDINE DERIVATIVES

#103
20120184734
2012-07-19

Substituted polycyclic carbamoylpyridone derivative

#104
20120107328
2012-05-03

Gamma secretase modulators

#105
20120071499
2012-03-22

Substituted Spiro[3H-Indole-3,6'(5'H)-[1H]Pyrrolo[1,2c]Imidazole-1',2(1H,2'H)-diones

#106
20120034660
2012-02-09

Process for producing optically active succinimide derivatives and intermediates thereof

#107
20120029044
2012-02-02

7-azoniabicyclo[2.2.1]heptane derivatives, methods of production, and pharmaceutical uses thereof

#108
20110319380
2011-12-29

Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof

#109
20110275613
2011-11-10

Organic compounds

#110
20110190497
2011-08-04

Process for production of 2,5 dioxopyrrolidine 3 carboxylate

#111
20110184171
2011-07-28

Acylation of hindered amines and functionalized bis-peptides obtained thereby

#112
20110152237
2011-06-23

Chemical compounds

#113
20110117651
2011-05-19

Cell adhesion promoting agent and method of promoting cell adhesion

#114
20110105548
2011-05-05

N-ARYL DIAZASPIROCYCLIC COMPOUNDS AND METHODS OF PREPARATION AND USE THEREOF

#115
20100063021
2010-03-11

Modulators of muscarinic receptors

#116
20090275560
2009-11-05

Organic compounds

#117
20080214591
2008-09-04

N-aryl diazaspirocyclic compounds and methods of preparation and use thereof

#118
20080113958
2008-05-15

Modulators of muscarinic receptors

#119
20080108632
2008-05-08

HCV PROTEASE INHIBITORS

#120
20060217406
2006-09-28

N-aryl diazaspiracyclic compounds and methods of preparation and use thereof

#121
20060057647
2006-03-16

Detection and identification of saxiphilins using saxitoxin-biotin conjugates

#122
20050272739
2005-12-08

N-aryl diazaspiracyclic compounds and methods of preparation and use thereof

#123
20050026901
2005-02-03

Antihistaminic spiro compounds

#124
17479669
2022-05-03

Macrocyclic spiropyrrolidine derived antiviral agents

#125
15467940
2018-02-20

Organic compound with tetrahedral-like geometry