96634 ⎘
General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
Sub-classes:COMPOSITIONS AND METHODS FOR MODIFICATION OF TARGET MOLECULES
#2PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST
#3METHOD FOR CLEAVING DISULFIDE BOND IN PROTEIN AND DEVICE FOR CLEAVING DISULFIDE BOND IN PROTEIN
#4ANTI-VEGF PROTEIN COMPOSITIONS AND METHODS FOR PRODUCING THE SAME
#5PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST
#6PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST
#7PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST
#8ANTI-VEGF PROTEIN COMPOSITIONS AND METHODS FOR PRODUCING THE SAME
#9Methods to imbue polymeric materials with new structures and functions
#10ANTI-VEGF PROTEIN COMPOSITIONS AND METHODS FOR PRODUCING THE SAME
#11PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST
#12PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST
#13CYCLIC PEPTIDE AND PREPARATION METHOD AND USE THEREOF
#14Anti-VEGF protein compositions and methods for producing the same
#15Anti-VEGF protein compositions and methods for producing the same
#16ANTI-VEGF PROTEIN COMPOSITIONS AND METHODS FOR PRODUCING THE SAME
#17DECARBOXYLATIVE CONJUGATE ADDITIONS AND APPLICATIONS THEREOF
#18PYRIDINIUM SALTS, METHODS OF MAKING, AND METHODS OF USE
#19MECHANOCHEMICAL GENERATION OF NOVEL COLLAGEN GEL ARCHITECTURES AND SCAFFOLDS
#20PEPTIDE-COMPOUND CYCLIZATION METHOD
#21PREPARATION OF MAYTANSINOID ANTIBODY CONJUGATES BY A ONE-STEP PROCESS
#22PROLINE-LOCKED STAPLED PEPTIDES AND USES THEREOF
#23Process for the preparation of cyclic depsipeptides
#24PREPARATION OF FUNCTIONAL HOMOCYSTEINE RESIDUES IN POLYPEPTIDES AND PEPTIDES
#25METHOD FOR SYNTHESIZING PEPTIDE THIOESTERS AND HEAD-TO-TAIL AMIDE CYCLIC PEPTIDE THEREOF
#26Anti-VEGF protein compositions and methods for producing the same
#27METHOD FOR PRODUCING INFLUENZA HA SPLIT VACCINE
#28POLYPEPTIDE OR PROTEIN DIRECTIONAL MODIFICATION METHOD BASED ON SULFHYDRYL-ALKENYL AZIDE COUPLING
#29Anti-VEGF protein compositions and methods for producing the same
#30Anti-VEGF protein compositions and methods for producing the same
#31Anti-VEGF protein compositions and methods for producing the same
#32Anti-VEGF protein compositions and methods for producing the same
#33METHOD FOR SYNTHESIS OF THIOETHER-CONTAINING PEPTIDES
#34HMGB1 antagonist treatment of severe sepsis
#35METHOD FOR CLEAVING DISULFIDE BOND IN PROTEIN AND DEVICE FOR CLEAVING DISULFIDE BOND IN PROTEIN
#36Anti-VEGF protein compositions and methods for producing the same
#37PEPTIDOMIMETIC MACROCYCLES
#38Anti-VEGF protein compositions and methods for producing the same
#39PEG-MODIFIED POLYPEPTIDE CAPABLE OF INHIBITING GP96, PREPARATION METHOD THEREFOR AND USE THEREOF
#40Anti-VEGF protein compositions and methods for producing the same
#41Anti-VEGF protein compositions and methods for producing the same
#42Anti-VEGF protein compositions and methods for producing the same
#43Stapled and stitched polypeptides and uses thereof
#44BIFUNCTIONAL STAPLED POLYPEPTIDES AND USES THEREOF
#45Anti-VEGF protein compositions and methods for producing the same
#46Anti-VEGF protein compositions and methods for producing the same
#47Anti-VEGF protein compositions and methods for producing the same
#48Anti-VEGF protein compositions and methods for producing the same
#49CYCLIC COMPOUNDS AND METHODS OF MAKING AND USING
#50PROLINE-LOCKED STAPLED PEPTIDES AND USES THEREOF
#51METHOD FOR MODIFYING AMINO GROUP IN MOLECULE WITH THE ZOLINIUM AND USE THEREOF
#52Anti-VEGF protein compositions and methods for producing the same
#53PEPTIDE COMPLEX AND PRODUCTION METHOD THEREFOR, AND USE OF SAID PEPTIDE COMPLEX
#54COMPOSITIONS AND METHODS FOR MODIFICATION OF TARGET MOLECULES
#55PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST
#56Preparation of maytansinoid antibody conjugates by a one-step process
#57Methods for producing aflibercept in chemically defined media having reduced aflibercept variants
#58Anti-VEGF protein compositions and methods for producing the same
#59Anti-VEGF protein compositions and methods for producing the same
#60Anti-VEGF protein compositions and methods for producing the same
#61Methods for producing aflibercept in chemically defined media having reduced aflibercept variants
#62CXCR3 LIGAND
#63ORTHO-PHTHALALDEHYDE CONTAINING LINKERS AND USE FOR PREPARATION OF ANTIBODY-DRUG CONJUGATE
#64Anti-VEGF protein compositions and methods for producing the same
#65Anti-VEGF protein compositions and methods for producing the same
#66Anti-VEGF protein compositions and methods for producing the same
#67Process for the preparation of cyclic depsipeptides
#68Decarboxylative conjugate additions and applications thereof
#69PEPTIDOMIMETIC MACROCYCLES
#70Anti-VEGF protein compositions and methods for producing the same
#71Solutions of quaternary and tertiary ammonium cation detergents to denature proteins, and kits for making them
#72Thiophosphorodichloridate reagents for chemoselective histidine bioconjugation
#73Anti-VEGF protein compositions and methods for producing the same
#74Anti-VEGF protein compositions and methods for producing the same
#75STAPLED PEPTIDES
#76Polypeptides Capable of Forming Homo-Oligomers with Modular Hydrogen Bond Network-Mediated Specificity and Their Design
#77Peptide-compound cyclization method
#78Production Method for Protein Molded Article, Production Method for Protein Solution, and Production Method for Protein
#79METHOD FOR DETECTING AN ANTIGEN-SPECIFIC ANTIBODY AND REAGENT FOR USE THEREIN
#80METHOD FOR EFFICIENTLY RECOVERING AND PURIFYING ACTIVE CRM197 FROM INSOLUBLE CRM197 PROTEIN EXPRESSED IN INCLUSION BODY
#81HMGB1 antagonist treatment of severe sepsis
#82HMGB1 antagonist treatment of acute lung injury
#83HMGB1 antagonist treatment of diabetic peripheral neuropathy
#84HMGB1 antagonist
#85Process for the preparation of cyclic depsipeptides
#86Preparation of maytansinoid antibody conjugates by a one-step process
#87Bispecific antibodies against HER2 and CD3
#88Stabilized anti-microbial peptides for the treatment of antibiotic-resistant bacterial infections
#89Asx-specific protein ligase
#90Conjugates comprising an GLP-1/Glucagon dual agonist, a linker and hyaluronic acid
#91Peptide-based multiple-drug delivery vehicle
#92Norbornene-based amphipathic compound and utilization thereof
#93Method for producing influenza HA split vaccine
#94Peptidomimetic macrocycles
#95Thiol-yne based peptide stapling and uses thereof
#96Stapled and stitched polypeptides and uses thereof
#97Selective Bfl-1 peptides
#98Process for the preparation of cyclic depsipeptides
#99Use of quaternary and tertiary ammonium cations to denature proteins
#100Dithioamine reducing agents
#101Preparation of functional homocysteine residues in polypeptides and peptides
#102Polypeptdes capable of forming homo-oligomers with modular hydrogen bond network-mediated specificity and their design
#103METHOD FOR GENERATING CELL-PENETRATING STAPLED PEPTIDES THAT LACK NONSPECIFIC MEMBRANE-LYTIC PROPERTIES FOR THERAPEUTIC TARGETING
#104METHODS FOR SYNTHESIZING PEPTIDE-TAGGED PEGYLATED CHITOSAN
#105Oxidized Aβ peptide
#106Stabilized compounds having secondary structure motifs
#107Preparation of maytansinoid antibody conjugates by a one-step process
#108Peptide-based multiple-drug delivery vehicle
#109Synthetic apolipoproteins, and related compositions methods and systems for nanolipoprotein particles formation
#110Decarboxylative conjugate additions and applications thereof
#111BIFUNCTIONAL STAPLED POLYPEPTIDES AND USES THEREOF
#112PROLINE-LOCKED STAPLED PEPTIDES AND USES THEREOF
#113BISPECIFIC ANTIBODIES AGAINST HER2 AND CD3
#114Methods of Improving Yield in Recombinant Protein Production
#115Cell penetrating stapled peptide, manufacturing method therefor, and use thereof
#116BIOLOGICALLY ACTIVE PEPTIDOMIMETIC MACROCYCLES
#117Peptidomimetic macrocycles
#118STIMULI-RESPONSIVE PROTEIN-POLYMER CONJUGATES FOR BIOSEPARATION
#119Cyclising peptides
#120Process for the preparation of cyclic depsipeptides
#121Stabilized compounds having secondary structure motifs
#122Stabilized P53 peptides and uses thereof
#123Chemically modifying peptides
#124Stitched polypeptides
#125Asx-specific protein ligase
#126Preparation of maytansinoid antibody conjugates by a one-step process
#127High molecular weight, post-translationally modified protein brushes
#128Cyclosporin analogs
#129Method for improving protein functionality using vortexing fluid shear forces
#130Cross-linked peptides containing non-peptide cross-linked structure, method for synthesizing cross-linked peptides, and novel organic compound used in method
#131PEPTIDE-COMPOUND CYCLIZATION METHOD
#132Triazole macrocycle systems
#133Triazole macrocycle systems
#134Method for cross-linking peptides
#135Method for preventing the unfolding of a (poly)peptide and/or inducing the (re-)folding of a (poly)peptide
#136Oxidized Aβ peptide
#137Stapled and stitched polypeptides and uses thereof
#138PROCESS FOR HIGH EFFICIENCY REFOLDING OF RECOMBINANT PROTEINS
#139Ordered two- and three-dimensional structures of amphiphilic molecules
#140DITHIOAMINE REDUCING AGENTS
#141Proline-locked stapled peptides and uses thereof
#142Methods of modifying N-termini of a peptide or protein using transferases
#143Stabilized p53 peptides and uses thereof
#144Peptide-compound cyclization method
#145Cyclosporin analogs
#146Method for producing reagent for antibody detection and use thereof
#147PREPARATION OF FUNCTIONALIZED POLYPEPTIDES, PEPTIDES, AND PROTEINS BY ALKYLATION OF THIOETHER GROUPS
#148Peptidomimetic macrocycles
#149Method for protein isolation in anoxic conditions
#150Method for modification of organic molecules
#151Preparation of maytansinoid antibody conjugates by a one-step process
#152Stabilized alpha helical peptides and uses thereof
#153BISPECIFIC ANTIBODIES AGAINST HER2 AND CD3
#154Stabilized compounds having secondary structure motifs
#155Macrocyclic hepatitis C serine protease inhibitors
#156Preparation method of micafungin sodium
#157Method for preventing the unfolding of a (poly)peptide and/or inducing the (re-)folding of a (poly)peptide
#158Methods for preparing internally constrained peptides and peptidomimetics
#159Aureobasidin derivatives and methods of synthesis
#160Stitched polypeptides
#161Beta-catenin targeting peptides and uses thereof
#162Cross-linked peptides containing non-peptide cross-linked structure, method for synthesizing cross-linked peptides, and novel organic compound used in method
#163Gelsolin stimulation of blood samples using gold particles
#164RADIATION CROSS-LINKED COLLAGEN GEL, AND PREPARATION METHOD AND USAGE METHOD THEREOF
#165Peptidomimetic macrocycles
#166Dithioamine reducing agents
#167Stabilized compounds having secondary structure motifs
#168Method for changing conformation of globular proteins
#169BIOLOGICALLY ACTIVE PEPTIDOMIMETIC MACROCYCLES
#170Methods for Preparing Internally Constrained Peptides and Peptidomimetics
#171Bifunctional stapled polypeptides and uses thereof
#172Preparation of maytansinoid antibody conjugates by a one-step process
#173High pressure refolding of monoclonal antibody aggregates
#174Macrocyclic hepatitis C serine protease inhibitors
#175Triazole macrocycle systems
#176Peptide libraries
#177Cyclosporin Analogs
#178Polypeptide protracting tags
#179Stabilized alpha helical peptides and uses thereof
#180Low viscosity highly concentrated suspensions
#181Triazole macrocycle systems
#182ORDERED TWO- AND THREE-DIMENSIONAL STRUCTURES OF AMPHIPHILIC MOLECULES
#183Biologically Active Peptidomimetic Macrocycles
#184Stabilized compounds having secondary structure motifs
#185METHOD AND AGENT FOR REFOLDING PROTEINS
#186Method for determining an equilibrium structure of a protein in a predetermined environment
#187Methods for preparing internally constrained peptides and peptidomimetics
#188Protein refolding column filler and column
#189Stitched polypeptides
#190Stabilized p53 peptides and uses thereof
#191Macrocyclic hepatitis C serine protease inhibitors
#192MODIFICATION OF ALLERGENS
#193BIOLOGICALLY ACTIVE PEPTIDOMIMETIC MACROCYCLES
#194C-TERMINUS MODIFICATION METHOD, C-TERMINUS IMMOBILIZATION METHOD AND ANALYSIS METHOD FOR PROTEIN OR PEPTIDE
#195Stabilized alpha helical peptides and uses thereof
#196Stabilized alpha helical peptides and uses thereof
#197Purification of HBV antigens for use in vaccines
#198Polypeptide protracting tags
#199HIGH PRESSURE REFOLDING OF MONOCLONAL ANTIBODY AGGREGATES
#200Folded recombinant catalytic fragments of multidomain serine proteases, preparation and uses thereof
#201Myeloid progenitor inhibitory factor-1 (MPIF-1) polypeptides
#202Triazole macrocycle systems
#203High-pressure inclusion body solubilization and protease clipping of recombinant fusion proteins
#204Selective reduction and derivatization of engineered proteins comprising at least one non-native cysteine
#205Use of tris(hydroxymethyl) aminomethane for the stabilization of peptides, polypeptides and proteins
#206Continuous Process for the Assembly of Macromolecular Substances and the Subsequent Capture and Isolation of Mamacromolecular Assembly and a System Suitable for the Process
#207Method for the Production of Recombinant Peptides with a Low Amount of Trisulfides
#208Methods for preparing internally constrained peptides and peptidomimetics
#209Protein/solubility folding assessed by structural complementation
#210Polyglutamine repeat sequences
#211Antibodies to myeloid progenitor inhibitory factor-1 (MPIF-1)
#212Purification of HBV antigens for use in vaccines
#213Method for protein isolation in anoxic conditions
#214Method of eliminating phosphate group of peptide and method of analyzing peptide
#215Methods for preparing internally constrained peptides and peptidomimetics
#216Stabilized compounds having secondary structure motifs
#217Stabilized alpha helical peptides and uses thereof
#218Folded recombinant catalytic fragments of multidomain serine proteases, preparation and uses thereof
#219Use of hydrostatic pressure to inhibit and reverse protein aggregation and facilitate protein refolding
#220Protein/solubility folding assessed by structural complementation
#221Ultra-stable protein ionic liquids
#222High-throughput crystallographic screening device and method for crystalizing membrane proteins using a sub physiological resting membrane potential across a lipid matrix of variable composition