ClassID:

97231

C07K16/461 - CPC Classification

Classification description:

Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies; Hybrid immunoglobulins Igs containing Ig-regions, -domains or -residues form different species

Sub-classes:
Recent Application in this class:
#1
20260071006
2026-03-12

MICE THAT MAKE VL BINDING PROTEINS

#2
20260020545
2026-01-22

NON-HUMAN ANIMALS HAVING AN ENGINEERED IMMUNOGLOBULIN LAMBDA LIGHT CHAIN AND USES THEREOF

#3
20250346677
2025-11-13

ANTIBODY MOLECULES

#4
20250197525
2025-06-19

HUMANIZED CHIMERIC BOVINE ANTIBODIES AND METHODS OF USE

#5
20250163127
2025-05-22

MULTI-DOMAIN IMMUNOMODULATORY PROTEINS AND METHODS OF USE THEREOF

#6
20250101118
2025-03-27

ANTIBODY MOLECULES

#7
20240409660
2024-12-12

ICOS LIGAND VARIANT IMMUNOMODULATORY PROTEINS AND USES THEREOF

#8
20240400720
2024-12-05

ANTI-CD47 ANTIBODIES AND METHODS OF USE THEREOF

#9
20240360227
2024-10-31

COMPOSITIONS AND METHODS FOR TREATMENT OF THYROID EYE DISEASE

#10
20240352154
2024-10-24

METHODS AND COMPOSITIONS RELATING TO HIGH-THROUGHPUT MODELS FOR ANTIBODY DISCOVERY AND/OR OPTIMIZATION

#11
20240343814
2024-10-17

COMPOSITIONS AND METHODS FOR TREATMENT OF THYROID EYE DISEASE

#12
20240327785
2024-10-03

HUMAN LAMBDA LIGHT CHAIN MICE

#13
20240306617
2024-09-19

ADAM6 MICE

#14
20240301075
2024-09-12

ANTIBODY MOLECULES

#15
20240268360
2024-08-15

METHOD FOR PREPARING TRANSGENIC NON-HUMAN ANIMAL HAVING GENOME INCLUDING HUMANIZED IMMUNOGLOBULIN GENE LOCUS

#16
20240254225
2024-08-01

ANTI-TREM-1 ANTIBODIES

#17
20240239919
2024-07-18

HUMAN IMMUNOGLOBULIN HEAVY CHAIN LONG CDR3 TRANSGENE CONSTRUCTS AND USES THEREOF

#18
20240065238
2024-02-29

HUMANIZED NON-HUMAN ANIMALS WITH RESTRICTED IMMUNOGLOBULIN HEAVY CHAIN LOCI

#19
20240010738
2024-01-11

ANTIBODY MOLECULES

#20
20230250163
2023-08-10

Anti-sclerostin antibodies and methods of use

#21
20230159660
2023-05-25

ANIMAL MODELS AND THERAPEUTIC MOLECULES

#22
20230159648
2023-05-25

ANTIBODY MOLECULES

#23
20230159627
2023-05-25

ANTI-C5A ANTIBODIES

#24
20230101432
2023-03-30

Multi-domain immunomodulatory proteins and methods of use thereof

#25
20230059489
2023-02-23

Antibodies specific for FLT3 and their uses

#26
20220325002
2022-10-13

EXPRESS HUMANIZATION OF ANTIBODIES

#27
20220315654
2022-10-06

BISPECIFIC ANTIBODIES TARGETING CD47 AND PD-L1 AND METHODS OF USE THEREOF

#28
20220306755
2022-09-29

ANTIBODY MOLECULES

#29
20220298256
2022-09-22

MODIFIED FC-REGIONS TO ENHANCE FUNCTIONAL AFFINITY OF ANTIBODIES AND ANTIGEN BINDING FRAGMENTS THEREOF

#30
20220295765
2022-09-22

Transgenic Non-Human Vertebrate for the Expression of Class-Switched, Fully Human, Antibodies

#31
20220177606
2022-06-09

MICE THAT MAKE VL BINDING PROTEINS

#32
20220177572
2022-06-09

RESTRICTED IMMUNOGLOBULIN HEAVY CHAIN MICE

#33
20220174920
2022-06-09

NON-HUMAN ANIMALS HAVING AN IMMUNOGLOBULIN HEAVY CHAIN VARIABLE REGION THAT INCLUDES AN ENGINEERED DIVERSITY CLUSTER AND USES THEREOF

#34
20220073649
2022-03-10

MIXED BINDING DOMAINS

#35
20220041741
2022-02-10

ANTIBODY MOLECULES

#36
20210395397
2021-12-23

ANTIGEN-BINDING MOLECULES COMPRISING UNPAIRED VARIABLE DOMAINS

#37
20210395377
2021-12-23

METHODS AND COMPOSITIONS RELATING TO ANTI-CHI3L1 ANTIBODY REAGENTS FOR THE TREATMENT OF FIBROSIS

#38
20210292439
2021-09-23

NON-HUMAN ANIMALS HAVING AN ENGINEERED IMMUNOGLOBULIN LAMBDA LIGHT CHAIN AND USES THEREOF

#39
20210238312
2021-08-05

METHODS AND COMPOSITIONS RELATING TO HIGH-THROUGHPUT MODELS FOR ANTIBODY DISCOVERY AND/OR OPTIMIZATION

#40
20210198383
2021-07-01

Method for determining the in vivo interaction mode

#41
20210189011
2021-06-24

Dual Variable Region Antibody-Like Binding Proteins Having Cross-Over Binding Region Orientation

#42
20210188995
2021-06-24

ICOS ligand variant immunomodulatory proteins and uses thereof

#43
20210163628
2021-06-03

MICE THAT MAKE VL BINDING PROTEINS

#44
20210105985
2021-04-15

ADAM6 mice

#45
20210105984
2021-04-15

ADAM6 mice

#46
20210079118
2021-03-18

ANIMAL MODELS AND THERAPEUTIC MOLECULES

#47
20210002385
2021-01-07

GENETIC ENGINEERING OF NON-HUMAN ANIMALS FOR THE PRODUCTION OF CHIMERIC ANTIBODIES

#48
20210000088
2021-01-07

TRANSGENIC CHICKEN THAT PRODUCES HUMAN ANTIBODIES

#49
20200407466
2020-12-31

Genetic engineering of non-human animals for the production of chimeric antibodies

#50
20200407465
2020-12-31

GENETIC ENGINEERING OF NON-HUMAN ANIMALS FOR THE PRODUCTION OF CHIMERIC ANTIBODIES

#51
20200407464
2020-12-31

Genetic engineering of non-human animals for the production of chimeric antibodies

#52
20200377619
2020-12-03

Genetic engineering of non-human animals for the production of chimeric antibodies

#53
20200354427
2020-11-12

Parathyroid hormone-anti-RANKL antibody fusion compounds

#54
20200308536
2020-10-01

Cell culture methods

#55
20200281175
2020-09-10

Humanized non-human animals with restricted immunoglobulin heavy chain loci

#56
20200239837
2020-07-30

HUMAN LAMBDA LIGHT CHAIN MICE

#57
20200239549
2020-07-30

Anti-HSV GB monoclonal antibody or antigen-binding fragment thereof

#58
20200231688
2020-07-23

ANTIBODY MOLECULES

#59
20200207875
2020-07-02

Method for preparing recombinant protein from bacterium and composition containing the same

#60
20200207842
2020-07-02

Anti-C5A antibodies

#61
20200181286
2020-06-11

Genetic engineering of non-human animals for the production of chimeric antibodies

#62
20200181285
2020-06-11

Genetic engineering of non-human animals for the production of chimeric antibodies

#63
20200157247
2020-05-21

Express humanization of antibodies

#64
20200093106
2020-03-26

Humanized non-human animals with restricted immunoglobulin heavy chain loci

#65
20200031952
2020-01-30

Method for treatment of an IL-17A-mediated disease through antibody administration specific to human IL-17A

#66
20190359731
2019-11-28

USE OF HUMAN CELLS OF MYELOID LEUKAEMIA ORIGIN FOR EXPRESSION OF ANTIBODIES

#67
20190359701
2019-11-28

METHODS OF TREATING DISEASES

#68
20190261612
2019-08-29

Restricted immunoglobulin heavy chain mice

#69
20190241654
2019-08-08

Antibodies with low immunogenicity and uses thereof

#70
20190223418
2019-07-25

Mouse having an engineered immunoglobulin lambda light chain

#71
20190208753
2019-07-11

Transgenic non-human vertebrate for the expression of class-switched, fully human, antibodies

#72
20190203171
2019-07-04

HUMAN LAMBDA LIGHT CHAIN MICE

#73
20190200588
2019-07-04

Humanized non-human animals with restricted immunoglobulin heavy chain loci

#74
20190153384
2019-05-23

HUMAN LAMBDA LIGHT CHAIN MICE

#75
20190037816
2019-02-07

RODENTS HAVING AN ENGINEERED HEAVY CHAIN DIVERSITY REGION

#76
20190016827
2019-01-17

METHOD FOR DETERMINING THE IN VIVO INTERACTION MODE

#77
20190010223
2019-01-10

Antagonists of IL-6 to prevent or treat thrombosis

#78
20180362663
2018-12-20

ADAM6 mice

#79
20180355065
2018-12-13

ANTI-CD47 ANTIBODIES AND METHODS OF USE THEREOF

#80
20180346601
2018-12-06

Antibodies specific for FLT3 and their uses

#81
20180346599
2018-12-06

ADAM6 mice

#82
20180346598
2018-12-06

ADAM6 mice

#83
20180345760
2018-12-06

ADAM6 mice

#84
20180334501
2018-11-22

METHODS OF TREATING DISEASES

#85
20180298112
2018-10-18

Animal models and therapeutic molecules

#86
20180291116
2018-10-11

ANTI-CD47 ANTIBODIES AND METHODS OF USE THEREOF

#87
20180291115
2018-10-11

Anti-CD47 antibodies and methods of use thereof

#88
20180273612
2018-09-27

Anti-C5a antibodies

#89
20180194847
2018-07-12

CD40L binding polypeptide

#90
20180170995
2018-06-21

P75NTR binding protein-Fc fusion protein and methods of treating pain

#91
20180155450
2018-06-07

Dual Variable Region Antibody-Like Binding Proteins Having Cross-Over Binding Region Orientation

#92
20180064078
2018-03-08

Human lambda light chain mice

#93
20180009887
2018-01-11

METHODS OF TREATING DISEASES

#94
20170320959
2017-11-09

ICOS ligand variant immunomodulatory proteins and uses thereof

#95
20170298143
2017-10-19

RSPO BINDING AGENTS AND USES THEREOF

#96
20170253660
2017-09-07

Anti-GD2 antibodies

#97
20170247473
2017-08-31

Express humanization of antibodies

#98
20170223939
2017-08-10

Mice that make Vbinding proteins

#99
20170218090
2017-08-03

Genetic engineering of non-human animals for the production of chimeric antibodies

#100
20170212107
2017-07-27

Velocity factor

#101
20170190797
2017-07-06

Genetic engineering of non-human animals for the production of chimeric antibodies

#102
20170190796
2017-07-06

Genetic engineering of non-human animals for the production of chimeric antibodies

#103
20170190795
2017-07-06

Genetic engineering of non-human animals for the production of chimeric antibodies

#104
20170190794
2017-07-06

Genetic engineering of non-human animals for the production of chimeric antibodies

#105
20170188558
2017-07-06

Genetic engineering of non-human animals for the production of chimeric antibodies

#106
20170188557
2017-07-06

Genetic engineering of non-human animals for the production of chimeric antibodies

#107
20170181414
2017-06-29

Genetic engineering of non-human animals for the production of chimeric antibodies

#108
20170107484
2017-04-20

Human lambda light chain mice

#109
20170096498
2017-04-06

Animal models and therapeutic molecules

#110
20170066843
2017-03-09

Anti-IL-17A Antibodies

#111
20160376357
2016-12-29

Methods of producing anti-C5a antibodies

#112
20160369012
2016-12-22

Hybrid constant regions

#113
20160304602
2016-10-20

METHODS OF TREATING DISEASES

#114
20160222132
2016-08-04

Constant chain modified bispecific, penta- and hexavalent Ig-M antibodies

#115
20160207997
2016-07-21

Methods of treating complement-associated disorders with anti-C5a antibodies

#116
20160176981
2016-06-23

Anti-GD2 antibodies

#117
20160132639
2016-05-12

Construction of diverse synthetic peptide and polypeptide libraries

#118
20160108091
2016-04-21

Cyclic polypeptides for the treatment of heart failure

#119
20160068602
2016-03-10

Sequence dependent aggregation

#120
20160060359
2016-03-03

Human lambda light chain mice

#121
20160057979
2016-03-03

Human lambda light chain mice

#122
20160002344
2016-01-07

Anti-RSPO2 antibodies and uses thereof

#123
20150368363
2015-12-24

Use of human cells of myeloid leukemia origin for expression of antibodies

#124
20150352205
2015-12-10

Antagonists of IL-6 to prevent or treat thrombosis

#125
20150351371
2015-12-10

Hybrid light chain mice

#126
20150246977
2015-09-03

Hybrid light chain mice

#127
20150246976
2015-09-03

Hybrid light chain mice

#128
20150239963
2015-08-27

Methods of treating a tauopathy

#129
20150210776
2015-07-30

ADAM6 mice

#130
20150201589
2015-07-23

ADAM6 mice

#131
20150183859
2015-07-02

Methods of treating complement-associated disorders with anti-C5a antibodies

#132
20150176002
2015-06-25

Method of cloning a lambda light chain variable domain using a human lambda light chain mouse

#133
20150173332
2015-06-25

Method of making antibodies using a human lambda light chain mouse

#134
20150173331
2015-06-25

Method of making antibodies using a human lambda light chain mouse

#135
20150166680
2015-06-18

Highly diverse combinatorial antibody libraries

#136
20150166666
2015-06-18

Methods of reducing IL-6 activity for disease treatment

#137
20150089680
2015-03-26

Human lambda light chain mice

#138
20150082466
2015-03-19

Transgenic non-human vertebrate for the expression of class-switched, fully human, antibodies

#139
20150057436
2015-02-26

Humanized antibodies

#140
20150031604
2015-01-29

Cyclic polypeptides for the treatment of heart failure

#141
20140328838
2014-11-06

CANINISED ANTIBODIES AND METHOD FOR PRODUCTION OF SAME

#142
20140303354
2014-10-09

Anti-CD47 antibodies and methods of use thereof

#143
20140256915
2014-09-11

Velocity factor

#144
20140234893
2014-08-21

Heterologous intron within an immunoglobulin domain

#145
20140213773
2014-07-31

ADAM6 mice

#146
20140170705
2014-06-19

Methods of generating libraries and uses thereof

#147
20140155580
2014-06-05

TRANSGENIC AVES PRODUCING HUMAN POLYCLONAL ANTIBODIES

#148
20140137275
2014-05-15

Hybrid light chain mice

#149
20140130193
2014-05-08

Mice that make VL binding proteins

#150
20140094392
2014-04-03

Methods of generating libraries and uses thereof

#151
20140056895
2014-02-27

Dual variable region antibody-like binding proteins having cross-over binding region orientation

#152
20140011238
2014-01-09

Dual variable region antibody-like binding proteins having cross-over binding region orientation

#153
20130333057
2013-12-12

Humanized non-human animals with restricted immunoglobulin heavy chain loci

#154
20130326647
2013-12-05

Human lambda light chain mice

#155
20130323790
2013-12-05

Human lambda light chain mice

#156
20130303399
2013-11-14

Express humanization of antibodies

#157
20130263292
2013-10-03

Animal models and therapeutic molecules

#158
20130224187
2013-08-29

Anti-C5a antibodies

#159
20130216529
2013-08-22

Humaneered anti-factor B antibody

#160
20130216528
2013-08-22

Anti-GD2 antibodies

#161
20130195850
2013-08-01

CD3 IMMUNOTHERAPEUTICS AND USES THEREOF

#162
20130189251
2013-07-25

Humanized antibodies targeting the EC1 domain of Cadherin-11 and related compositions and methods

#163
20130129721
2013-05-23

Methods of inhibiting the interaction of C5aR with C5a with anti-C5aR antibodies

#164
20130071366
2013-03-21

Insulin-like growth factor II (IGF-II) binding factors

#165
20130065277
2013-03-14

Sequence dependent aggregation

#166
20130058949
2013-03-07

Antagonists of IL-6 to prevent or treat thrombosis

#167
20120322108
2012-12-20

ADAM6 mice

#168
20120316085
2012-12-13

Antibody humanization by framework assembly

#169
20120315275
2012-12-13

Humanized anti-C5aR antibodies

#170
20120253016
2012-10-04

ANTIBODY MOLECULES THAT BIND TO IL-6 RECEPTOR

#171
20120251541
2012-10-04

Dual Variable Region Antibody-Like Binding Proteins Having Cross-Over Binding Region Orientation

#172
20120230981
2012-09-13

CH2 domain template molecules derived from rational grafting of donor loops onto CH2 scaffolds

#173
20120202716
2012-08-09

Construction of diverse synthetic peptide and polypeptide libraries

#174
20120156726
2012-06-21

Velocity factor

#175
20120129731
2012-05-24

Design and construction of diverse synthetic peptide and polypeptide libraries

#176
20120096572
2012-04-19

Mice that make VL binding proteins

#177
20120073004
2012-03-22

Hybrid light chain mice

#178
20120070861
2012-03-22

Human lambda light chain mice

#179
20120028301
2012-02-02

SOMATIC HYPERMUTATION SYSTEMS

#180
20110318337
2011-12-29

HUMANEERED ANTI-FACTOR B ANTIBODY

#181
20110287485
2011-11-24

Methods of generating libraries and uses thereof

#182
20110277048
2011-11-10

Transgenic Aves Producing Human Polyclonal Antibodies

#183
20110277047
2011-11-10

Genetically modified non-human mammals and cells

#184
20110190477
2011-08-04

Humanized anti-C5aR antibodies

#185
20110183855
2011-07-28

SOMATIC HYPERMUTATION SYSTEMS

#186
20110171208
2011-07-14

CD37 immunotherapeutics and uses thereof

#187
20110166844
2011-07-07

Systems and methods for antibody engineering

#188
20110165621
2011-07-07

Humanized antibodies

#189
20110098450
2011-04-28

Antibody molecules that bind to IL-6 receptor

#190
20100261620
2010-10-14

Methods of Humanizing and Affinity-Maturing Antibodies

#191
20100205682
2010-08-12

Humanized immunoglobulin loci

#192
20100121039
2010-05-13

METHODS AND COMPOSITIONS FOR PROLONGING ELIMINATION HALF-TIMES OF BIOACTIVE COMPOUNDS

#193
20100028947
2010-02-04

Use of human cells of myeloid leukaemia origin for expression of antibodies

#194
20090304651
2009-12-10

Insulin-like growth factor II (IGF-II) binding factors

#195
20090291089
2009-11-26

Antagonists of IL-6 to prevent or treat thrombosis

#196
20090274692
2009-11-05

CD37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof

#197
20090238825
2009-09-24

NOVEL RABBIT ANTIBODY HUMANIZATION METHODS AND HUMANIZED RABBIT ANTIBODIES

#198
20090226430
2009-09-10

RECOMBINANT ANTI-CD4 ANTIBODIES FOR HUMAN THERAPY

#199
20090221036
2009-09-03

RECOMBINANT ANTI-CD4 ANTIBODIES FOR HUMAN THERAPY

#200
20090169548
2009-07-02

BINDING MOLECULES

#201
20090104187
2009-04-23

Novel Rabbit Antibody Humanization Methods and Humanized Rabbit Antibodies

#202
20090093024
2009-04-09

Methods of generating libraries and uses thereof

#203
20090082213
2009-03-26

Construction of diverse synthetic peptide and polypeptide libraries

#204
20090075378
2009-03-19

Somatic hypermutation systems

#205
20080299618
2008-12-04

SINGLE DOMAIN LIGANDS, RECEPTORS COMPRISING SAID LIGANDS, METHODS FOR THEIR PRODUCTION AND USE OF SAID LIGANDS AND RECEPTORS

#206
20080299114
2008-12-04

Humaneered anti-factor B antibody

#207
20080118939
2008-05-22

Conjugate and its use as a standard in an immunoassay

#208
20080050357
2008-02-28

Systems and Methods for Antibody Engineering

#209
20070160534
2007-07-12

Methods and compositions for prolonging elimination half-times of bioactive compounds

#210
20070021595
2007-01-25

Humanized antibody and process for preparing same

#211
20070014796
2007-01-18

De-immunized streptokinase

#212
20060236418
2006-10-19

Genetically modified non-human mammals and cells

#213
20060073137
2006-04-06

Humanised antibodies

#214
20060073136
2006-04-06

Humanised antibodies

#215
20060029593
2006-02-09

Humanised antibodies

#216
20060026696
2006-02-02

Humanized immunoglobulin loci

#217
20050246782
2005-11-03

Transgenic aves producing human polyclonal antibodies

#218
20050202529
2005-09-15

Humanised antibodies

#219
20050176028
2005-08-11

Deimmunized binding molecules to CD3

#220
20050136054
2005-06-23

Humanised antibodies

#221
20050123534
2005-06-09

Humanised antibodies

#222
20050059082
2005-03-17

Method for producing protein libraries and for selecting proteins from said libraries

#223
20050033031
2005-02-10

Methods for humanizing rabbit monoclonal antibodies