Crystal structure and uses thereof

Crystal structure of human Janus Kinase 2 (JAK2) and uses thereof

Crystals of inosine monophosphate dehydrogenase/oxidized inosine monophosphate thiomidate intermediate/mycophenolic acid (IIMPDH/XMP*/MPA)

Solid forms of anti-EGFR antibodies

Aggrecanase structure

Crystal of a transporter-ligand complex and methods of use

Crystal structures of MK2 and uses thereof

Method for making β-secretase co-crystals complexed with a ligand

Method for designing surfaces

Ecdysone receptor ligand-binding domain structure

Crystalline VAP-1 and uses thereof

Cytokine polypeptides

Methionine aminopeptidase and methods of use

Glycogen synthase kinase-3 inhibitors

Three-dimensional structure of the catalytic domain of protein kinase c theta, methods and uses thereof

Protein crystal

Bcl-w structure and uses therefor

Protein Structure Determination

Variants and chemically-modified variants of phenylalanine ammonia-lyase

Carnitine palmitoyltransferase II crystals

CRYSTAL STRUCTURES AND MODELS FOR Fc RECEPTORS AND USES THEREOF IN THE DESIGN OR IDENTIFICATION OF Fc RECEPTOR MODULATOR COMPOUNDS

Crystal structure of erythrocyte binding domain of EBA-175

Crystallized structure of type IV collagen NC1 domain hexamer

Modified TRAP protein for producing nano-scale electrical devices, and a method for producing such a protein

HCV polymerase suitable for crystal structure analysis and method for using the enzyme

Structure-based selection and affinity maturation of antibody library

Generation and selection of protein library in silico

Cytokine receptor

EGR-EGFR complex

Crystal structure of the ITK kinase domain

Crystal structure of human Pim-1 kinase protein complexes and binding pockets thereof, and uses thereof in drug design

Three-dimensional structure of DNA recombination/repair protein and use thereof

Catalytic domain of ADAM33 and methods of use thereof

Nuclear receptor ligands and ligand binding domains

Atomic structure of the catalytic domain for use in designing and identifying inhibitors of zap-70 kinase

Crystalline Neutrokine-alpha protein, method of preparation thereof, and method of use thereof

3-structure of a whole integrin $g(a) v$g(b) extracellular region and uses therefor

Selective resonance of bodily agents

Structural-based inhibitors of the glutathione binding site in aldose reductase, methods of screening therefor and methods of use

Method for crystallizing human GSK3 and novel crystal structure thereof

Method for site-specific protein modifications

Structure of a glucocorticoid receptor ligand binding domain comprising an expanded binding pocket and methods employing same

Spleen tyrosine kinase catalytic domain:crystal structure and binding pockets thereof

Essential fungal polynucleotides, polypeptides, and methods of use

Three-dimensional structures of TALL-1 and its cognate receptors and modified proteins and methods related thereto

Subtilases

Crystal structure of phosphodiesterase 5 and use thereof

Crystal structures of YHHF polypeptides

G protein-coupled receptor structural model and a method of designing ligand binding to g protein-coupled receptor by using the structural model

Crystal structure of liganded cFMS kinase domain

PEGylated TNF-α variant proteins

Crystal structures of aspartate semialdehyde dehydrogenases

Car ligand-binding domain polypeptide co-crystallized with a ligand, and methods of designing ligands that modulate car activity

Crystallization of IGF-1

Resistant-repellent retroviral protease inhibitors

Crystallization of IGF-1

Crystallization of IGF-1

Crystallization of IGF-1

Crystallization of IGF-1

Polynucleotide encoding a mutant transglutaminase

Molecule

Crystallization of IGF-1

Crystallized structure of estrogen related receptor gamma in complex with bisphenol A

Crystal structure of SNAP-25 in complex with botulinum neurotoxin and uses thereof

Purified polypeptides from

Resistance-repellent retroviral protease inhibitors

Switch-region: target and method for inhibition of bacterial RNA polymerase

Peptides for active anti-cytokine immunization

Crystals and structure of Synagis Fab

CNG2B: a novel human cyclic nucleotide-gated ion channel

Structure of a complex of retinoblastoma protein bound to e2f, and uses thereof

Polypeptide methods and means

Method of inhibiting insulin-like growth factor-1 (IGF-1) by IGF-1-antagonist peptides

AI-2 compounds and analogs based on Salmonella typhimurium LsrB structure

Controlled dissolution crosslinked protein in crystals

Crystal structure of chorismate synthase and uses thereof

One-dimensional QSAR models

Structure of the farnesoid X receptor ligand binding domain and methods of use therefor

Viral polymerase and modulation thereof

Peptides for diagnostic and therapeutic methods for celiac sprue

Crystal structure of worm NitFhit reveals that a Nit tetramer binds tow Fhit dimers

Polynucleotide encoding a novel cysteine protease of the calpain superfamily, CAN-12, and variants thereof

Method for the crystallization of human serum albumin

Murine IL-18 crystal structure

Computational method for designing enzymes for incorporation of amino acid analogs into proteins

Crystal structure of an angiotensin-converting enzyme (ACE) and uses thereof

Crystalline phosphatase and method for use thereof

Methods for the design of estrogen receptor ligands

Cyclic agonists and antagonists of C5a receptors and G protein-coupled receptors

Three-dimensional structures of HDAC9 and Cabin1 and compound structures and methods related thereto

Guanylate cyclase receptor agonists for the treatment of tissue inflammation and carcinogenesis

Method for obtaining dynamic and structural data pertaining to proteins and protein/ligand complexes

IGF antagonist peptides

Polynucleotide encoding a novel human serpin secreted from lymphoid cells, LSI-01

Information processing system using base sequence relevant information

Methods of identifying and designing cell surface receptor inhibitors

Methods and compositions related to argonaute proteins

Crystals of glucokinase and methods of growing them

Methods and compositions for milieu-dependent binding of a targeted agent to a target

MODULATORS OF RIBOSOMAL FUNCTION AND IDENTIFICATION THEREOF

Method for crystallizing human beta secretase in complex with an inhibitor

Crystal structure of baff, and use thereof in drug design

Erbb4 co-crystal

Mitotic kinesin binding site

Crystals and structure of domain III of West Nile Virus envelope protein in association with a Fab fragment of a neutralizing antibody

Methods and compositions for treating cellular proliferative diseases

Method for designing a potential inhibitor of glutathione-aldehyde conjugate binding to aldose reductase

Controlled dissolution crosslinked protein crystals

Structural models of carnitine acyltransferases and uses thereof

Crystal structure of the c-fms kinase domain: applications and use of heterologous substitutions of kinase insert domains for crystallization

ERK2 crystals

Crystal structures of NH3-dependent NAD synthetases

Novel purified polypeptides from Enterococcus faecalis

Crystal structures of bacterial thymidylate kinases

Novel purified hydroxymethylglutaryl-CoA reductases and structures thereof

Novel purified polypeptides from haemophilus influenzae

Determination of a phosphorylation site in PPIase domain of Pin1 and uses therefor

Design of progesterone receptor ligands

Rab9 protein crystal structures and methods for identifying Rab9 modulators

Crystal structures of bacterial guanylate kinases

Crystal structure of house dust mite allergen Der p 1

Structure-based modulators of B1 G-protein coupled receptors

Glycogen synthase kinase-3 inhibitors

Crystal structure of the complex of hepatocyte growth factor beta chain with Met receptor and methods of use

AI-2 compounds and analogs based on LsrB structure

Antibodies against human interleukin-13 and pharmaceutical compositions thereof

Crystals of the Fc region of immunoglobulin epsilon heavy chain protein

Anticalins

Methods and compositions for cancer treatment relating to BRCA1 BRCT domain recognition of phosphorylated BACH1

Crystal of bacterial core RNA polymerase and methods of use thereof

Three-dimensional model of a complex between a Fc epsilon receptor alpha chain and a Fc region of an IgE antibody and uses thereof

Use of the protein maba (fabg1) of mycobacterium tuberculosis for designing and screening antibiotics

Crystal structure of human JAK3 kinase domain complex and binding pockets thereof

Three-dimensional structure of c-Abl

Crystal structure of interleukin-2 tyrosine kinase (ITK) and binding pockets thereof

Position dependent recognition of GNN nucleotide triplets by zinc fingers

Position dependent recognition of GNN nucleotide triplets by zinc fingers

Three-dimensional structure of complement receptor type 2 and uses thereof

Complexes of protein crystals and ionic polymers

Crystal structure of the hepatocyte growth factor and methods of use

Novel purified polypeptides from enterococcus faecalis

Structure of protein kinase C theta

Subunit vaccine against West Nile viral infection

Cold shock inducible expression and production of heterologous polypeptides

Ribosome structure and protein synthesis inhibitors

Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule

Crystal structure of mitogen-activated protein kinase-activated protein kinase 2 and binding pockets thereof

Three-dimensional structure of dipeptidyl peptidase IV

Crystal structure of the mitochondrial protoporphyrinogen IX oxidase

Modified G-CSF polypeptide

Drug therapy for celiac sprue

Three-dimensional structure of prostaglandin D synthase and utilization thereof

Novel purified polypeptides from Pseudomonas aeruginosa

Variant aldolase and processes for producing an optically active IHOG and an optically active monatin using the same

Peptidyl-tRNA hydrolase of Enterococcus faecalis

Solution phase biopanning method using engineered decoy proteins

Ribosome structure and protein synthesis inhibitors

Human cyclic nucleotide-gated cation channel polypeptide

Crystal structure of ribosomal protein L11/GTPase activating region rRNA and uses thereof

Methods and compositions comprising bacteriophage nanoparticles

Novel purified polypeptides from pseudomonas aeruginosa

Method for identifying or screening anti-viral agents

Crystallization of IGF-1

Novel purified polypeptides from streptococcus pneumoniae

Small and intermediate conductance, calcium-activated potassium channels and uses thereof

Novel purified polypeptides from bacteria

Bactericidal/permeability-increasing protein: crystallization, x-ray diffraction, three-dimensional structure determination, rational drug design and molecular modeling or related proteins

Crystal structure of staphylococcus undecaprenyl pyrophosphate synthase and uses thereof

Compositions and methods for hydroxylating epothilones

Peptides that bind to broadly neutralizing anti-HIV antibody-structure of 4E10 Fab fragment complex. uses thereof, compositions therefrom

Ligand binding pocket peptide fragment of estrogen-related receptor 3 (err3) and uses thereof

Method of screening drug

Crystal structure of 3', 5'-cyclic nucleotide phosphodiesterase (PDE10A) and uses thereof

Crystal structure

Crystalline structure of oxidosqualene synthase

Crystal structure of VEGFRKD: ligand complexes and methods of use thereof

Crystal structure of the BTK kinase domain

Products and processes for modulating peptide-peptide binding domain interactions

Novel purified polypeptides from Streptococcus pneumoniae

Three-dimensional model of a Fc region of an IgE antibody and uses thereof

Structure-based design and synthesis of FGF inhibitors and FGF modulator compounds

Method of rational-based drug design using osteocalcin

Crystal structure of FMS-like tyrosine kinase

Crystallized glucocorticoid receptor ligand binding domain polypeptide and screening methods employing same

Crystal structure

Three dimensional coordinates of melanocortin-4 receptors

Three dimensional coordinates of melanin-concentrating hormone receptors

PYK2 crystal structure and uses

Oligomerization of hepatitis delta antigen

Crystal structure of the ligand binding domain of the retinoic acid-related orphan receptor alpha (ror-alpha)

Novel purified polypeptides from staphylococcus aureus

Novel purified polypeptides from pseudomonas aeruginosa

Crystal structure of cytochrome P450

Novel purified polypeptides from Streptococcus pneumoniae

Crystal structure of the 30S ribosome and its use

Maleic acid salt of(2s)-n-{5-[amino(imino)methy]-2-thienyl}methyl-1-{(2r)-2-[(carboxymethyl)amino]-3,3-diphenylpropanoyl}-2-pyrrolidine carboxamide and a process for

Inhibition of immune complex formation

Structure-based construction of human antibody library

Method and apparatus for generating biologically-active-substance candidate structure, and computer product

Crystal structure of aurora-2 protein and binding pockets thereof

Crystallized hnf4 gamma ligand binding domain polypeptide and screening methods employing same

Crystallisation of a GLP-1 analogue

STRUCTURE OF INTEGRIN ALPHA V-beta 3 EXTRACELLULAR DOMAIN COMPLEXED WITH LIGAND

Methods for rational pegylation of proteins

Crystalline forms(2s)-n-5[amino(imino)methyl]-2-thienylmethyl-1-(2r)-2[(carboxymethyl) amino]-3,3-diphenylpropanoyl-2-pyrrolidinecarboxamide nh2o

Crystals and structures of protein kinase CHK2

Methods and apparatus for protein sequence analysis

Resistance-repellent retroviral protease inhibitors

Crystals and structures of c-Abl tyrosine kinase domain

Diagnosis and treatment of infectious diseases through indel-differentiated proteins

Polo domain structure

Crystal structure of 3', 5'-cyclic nucleotide phosphodiesterase (PDE1B) and uses thereof

Crystal of bacterial core RNA polymerase with rifampicin and methods of use thereof

PDE5A crystal structure and uses

S8 rRNA-binding protein from the small ribosomal subunit of

Crystal structure of glutamate racemase (MurI)

Modified Wee1, crystals of peptide: inhibitor complexes containing such modified Wee1, and methods of use thereof

Soluble, stable form of HDM2, crystalline forms thereof and methods of use thereof

Method of identifying molecules that bind to the large ribosomal subunit

Mutants of igf binding proteins and methods of production of antagonists thereof

Crystal structure of cytochrome P450

Computer-based methods of designing molecules

Method for the prediction of binding targets and the design of ligands

Carboxyltransferase domain of acetyl-CoA carboxylase

Structures and methods for designing topoisomerase I inhibitors

Hepatitis C Virus NS5B polymerase inhibitor binding pocket

N-TRADD active site and uses thereof

C.difficile toxin B CROP domain peptides, antibodies and complexes thereof

Human growth hormone crystals and methods for preparing them