ClassID:

97279

C07K2317/53 - page 3 - CPC Classification

Classification description:

Immunoglobulins specific features characterized by immunoglobulin fragments; Constant or Fc region; Isotype Hinge

Recent Application in this class:
#601
20220112296
2022-04-14

ANTIGEN-BINDING MOLECULE COMPRISING ALTERED ANTIBODY VARIABLE REGION

#602
20220106400
2022-04-07

ANTIBODIES COMPRISING MODIFIED HEAVY CONSTANT REGIONS

#603
20220098307
2022-03-31

MODIFIED FC FRAGMENT, ANTIBODY COMPRISING SAME, AND APPLICATION THEREOF

#604
20220098306
2022-03-31

Anti-CD28 compositions

#605
20220098273
2022-03-31

Chimeric engulfment receptor molecules

#606
20220090017
2022-03-24

CONTROLLING PROXIMITY OF IMMUNE CELL RECEPTORS

#607
20220090016
2022-03-24

ENGINEERED IMMUNE CELLS WITH MICRO-CLUSTERS

#608
20220090015
2022-03-24

ENGINEERED IMMUNE CELLS WITH MULTIPLEX AND LOCALIZED ACTIVITY

#609
20220090014
2022-03-24

Engineered immune cells with receptor cross-talk

#610
20220090013
2022-03-24

ENGINEERING IMMUNE CELLS BASED ON ANTIGEN LEVELS

#611
20220089769
2022-03-24

REMOVAL OF TARGET CELLS BY CIRCULATING VIRUS-SPECIFIC CYTOTOXIC T-CELLS USING MHC CLASS I COMPRISING COMPLEXES

#612
20220089768
2022-03-24

MULTI-SPECIFIC PROTEIN MOLECULES AND USES THEREOF

#613
20220089739
2022-03-24

Antibodies Directed Against Programmed Death-1 (PD-1)

#614
20220089730
2022-03-24

ANTIGEN BINDING CONSTRUCTS TO TARGET MOLECULES

#615
20220089718
2022-03-24

CHIMERIC ANTIGEN RECEPTORS WITH MODIFIED LINKER DOMAINS AND USES THEREOF

#616
20220089678
2022-03-24

Anti-BCMA chimeric antigen receptors

#617
20220089676
2022-03-24

Engineered immune cells with receptor signal strength modulated by a hinge

#618
20220089675
2022-03-24

Engineered immune cells with dominant signals

#619
20220073876
2022-03-10

Modified B cells and methods of use thereof

#620
20220073602
2022-03-10

Antibodies with improved stability to intestinal digestion, polynucleotides thereof and methods of use thereof to treat disease

#621
20220073585
2022-03-10

CHIMERIC ANTIGEN RECEPTOR MEMORY-LIKE (CARML) NK CELLS AND METHODS OF MAKING AND USING SAME

#622
20220072041
2022-03-10

GENE MODIFIED IMMUNE EFFECTOR CELLS AND ENGINEERED CELLS FOR EXPANSION OF IMMUNE EFFECTOR CELLS

#623
20220064337
2022-03-03

ANTIGEN BINDING FORMATS FOR RECEPTOR COMPLEXES

#624
20220064317
2022-03-03

Multispecific antibodies against CD40 and CD137

#625
20220064300
2022-03-03

MODIFIED ANTIBODIES

#626
20220064298
2022-03-03

COMPOSITIONS AND METHODS RELATED TO ENGINEERED Fc-ANTIGEN BINDING DOMAIN CONSTRUCTS TARGETED TO CTLA-4

#627
20220064292
2022-03-03

Drug regulated transgene expression

#628
20220064264
2022-03-03

ANTIBODY CONSTANT REGION VARIANT

#629
20220064254
2022-03-03

Anti-human kallikrein-2 (hK2) chimeric antigen receptor (CAR) and methods of use thereof

#630
20220056146
2022-02-24

Antibodies and Antigen Binding Fragments Against CD155 Methods of Use Thereof

#631
20220056143
2022-02-24

Caninized human antibodies to human IL-4R alpha

#632
20220056089
2022-02-24

ENGINEERED OPSONIN FOR PATHOGEN DETECTION AND TREATMENT

#633
20220049019
2022-02-17

Compositions and methods related to engineered Fc constructs

#634
20220049004
2022-02-17

Engineered immune cells targeting BCMA and their uses thereof

#635
20220048978
2022-02-17

CR3022 chimeric antigen receptors and methods of use

#636
20220041721
2022-02-10

CD3 antigen binding fragment and application thereof

#637
20220041702
2022-02-10

Antibody molecules comprising a single-domain antigen-binding site and Fab fragments

#638
20220033526
2022-02-03

ACTIVATABLE THERAPEUTIC MULTISPECIFIC POLYPEPTIDES WITH EXTENDED HALF-LIFE

#639
20220033510
2022-02-03

Multispecific antibodies against CD40 and CD137

#640
20220025329
2022-01-27

CHIMERIC ANTIGEN RECEPTOR-MODIFIED NK-92 CELLS TARGETING EGFR SUPER-FAMILY RECEPTORS

#641
20220025022
2022-01-27

Anti-ETEC adhesin protein antibodies and methods of use

#642
20220018845
2022-01-20

Articles and methods directed to personalized therapy of cancer

#643
20220017587
2022-01-20

Dual cytokine fusion proteins comprising IL-10

#644
20220010030
2022-01-13

METHOD FOR PRODUCING POLYPEPTIDE HETERO-OLIGOMER

#645
20220002675
2022-01-06

Constructs for chimeric antigen receptors

#646
20220002386
2022-01-06

Production of heteromultimeric proteins using mammalian cells

#647
20220000918
2022-01-06

Method of increasing tumor killing activity of macrophages or monocytes comprising chimeric antigen receptor

#648
20220000917
2022-01-06

NOVEL CONSTRUCTS FOR CHIMERIC ANTIGEN RECEPTORS

#649
20210403596
2021-12-30

Chimeric antigen receptor

#650
20210403574
2021-12-30

Chimeric antigen receptors against multiple HLA-G isoforms

#651
20210403572
2021-12-30

HLA binding vaccine moieties and uses thereof

#652
20210401890
2021-12-30

CHIMERIC ANTIGEN RECEPTOR T LYMPHOCYTE FOR TREATING TUMORS, PREPARATION METHOD THEREFOR, AND USE THEREOF

#653
20210395383
2021-12-23

Anti-PSGL-1 antibodies and uses thereof

#654
20210395372
2021-12-23

Anti-Met fab-Fc for the treatment of a tumor and/or metastasis

#655
20210395363
2021-12-23

METHODS AND COMPOSITIONS FOR INHIBITING CD32B EXPRESSING CELLS

#656
20210395329
2021-12-23

CD6 targeted chimeric antigen receptors for treatment of certain autoimmune disorders

#657
20210393690
2021-12-23

METHODS FOR TREATMENT USING CHIMERIC ANTIGEN RECEPTORS SPECIFIC FOR B-CELL MATURATION ANTIGEN

#658
20210380713
2021-12-09

Bispecific antibody which binds to CD40 and EpCAM

#659
20210380684
2021-12-09

ANTIBODY COMPOSITION

#660
20210371527
2021-12-02

ANTIGEN BINDING CONSTRUCTS TO CD4

#661
20210371526
2021-12-02

HOMODIMERIC BISPECIFIC ANTIBODY, PREPARATION METHOD THEREFOR AND USE THEREOF

#662
20210368751
2021-12-02

HUMANIZED RODENTS THAT EXPRESS HEAVY CHAIN CONTAINING VL DOMAINS

#663
20210364500
2021-11-25

Rat model of IgA nephropathy induced with a multimeric recombinant IgA fragment

#664
20210363261
2021-11-25

PROTEIN BINDING NKG2D, CD16 AND A FIBROBLAST ACTIVATION PROTEIN

#665
20210363219
2021-11-25

PD-1 variant immunomodulatory proteins and uses thereof

#666
20210361710
2021-11-25

Construction of chimeric antigen receptor targeting CD20 antigen and activity identification of engineered T cells thereof

#667
20210355238
2021-11-18

NON-HUMAN ANIMALS THAT SELECT FOR LIGHT CHAIN VARIABLE REGIONS THAT BIND ANTIGEN

#668
20210355184
2021-11-18

IL10 agonists and methods of use thereof

#669
20210347916
2021-11-11

CONTORSBODY - A SINGLE CHAIN TARGET BINDER

#670
20210347907
2021-11-11

MODIFIED ANTIBODIES CONTAINING MODIFIED IGG2 DOMAINS WHICH ELICIT AGONIST OR ANTAGONISTIC PROPERTIES AND USE THEREOF

#671
20210347905
2021-11-11

Mesothelin-targeted CD40 agonistic multispecific antibody constructs for the treatment of solid tumors

#672
20210347852
2021-11-11

VEGF traps and mini-traps and methods for treating ocular disorders and cancer

#673
20210347850
2021-11-11

Fc-epsilon car

#674
20210340573
2021-11-04

Rapamycin resistant cells

#675
20210340281
2021-11-04

FUSION POLYPEPTIDE COMPRISING POLYPEPTIDE REGION THAT CAN BE O-GLYCOSYLATED

#676
20210340268
2021-11-04

ANTAGONISTIC ANTI-TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY POLYPEPTIDES

#677
20210333282
2021-10-28

ARTICLES AND METHODS DIRECTED TO PERSONALIZED THERAPY OF CANCER

#678
20210332105
2021-10-28

Compositions and methods of treating cancer with chimeric antigen receptors

#679
20210324108
2021-10-21

Bispecific 2+1 contorsbodies

#680
20210324105
2021-10-21

BISPECIFIC ANTIBODIES AGAINST HER2

#681
20210324100
2021-10-21

CHIMERIC ANTIGEN RECEPTORS SPECIFIC FOR B-CELL MATURATION ANTIGEN AND ENCODING POLYNUCLEOTIDES

#682
20210324074
2021-10-21

Affinity matured CD22-specific monoclonal antibody and uses thereof

#683
20210324064
2021-10-21

HEAVY CHAIN ONLY ANTIBODIES TO ANG-2

#684
20210324043
2021-10-21

ApoC-II mimetic peptides

#685
20210317227
2021-10-14

COMPOSITIONS AND METHODS RELATED TO ENGINEERED Fc-ANTIGEN BINDING DOMAIN CONSTRUCTS

#686
20210317225
2021-10-14

Multispecific antibodies against CD40 and CD137

#687
20210317223
2021-10-14

MULTI-SPECIFIC BINDING PROTEINS THAT BIND BCMA, NKG2D AND CD16, AND METHODS OF USE

#688
20210317222
2021-10-14

IMMUNOMODULATORY ANTIBODIES

#689
20210317207
2021-10-14

ANTI-HUMAN VISTA ANTIBODIES AND USE THEREOF

#690
20210317206
2021-10-14

ANTI-HUMAN VISTA ANTIBODIES AND USE THEREOF

#691
20210317183
2021-10-14

Enhanced antigen presenting ability of RNA car T cells by co-introduction of costimulatory molecules

#692
20210308184
2021-10-07

TAG72 targeted chimeric antigen receptor modified T cells for treatment of TAG72-positive tumors

#693
20210299224
2021-09-30

Methods and compositions for treating autoimmune and inflammatory conditions

#694
20210299172
2021-09-30

ENGINEERED PHAGOCYTIC RECEPTOR COMPOSITIONS AND METHODS OF USE THEREOF

#695
20210292420
2021-09-23

PROTEINS BINDING NKG2D, CD16 AND A TUMOR-ASSOCIATED ANTIGEN

#696
20210284717
2021-09-16

COMPOSITIONS AND METHODS RELATED TO ENGINEERED FC-ANTIGEN BINDING DOMAIN CONSTRUCTS

#697
20210277132
2021-09-09

CD70 binding molecules and methods of use thereof

#698
20210269533
2021-09-02

ANTI-C-MET ANTIBODY AND USES THEREOF

#699
20210268061
2021-09-02

Methods of use of CD24 for the prevention and treatment of leukemia relapse

#700
20210268027
2021-09-02

CHIMERIC ANTIGEN RECEPTORS TARGETING CD37 AND CD19

#701
20210268024
2021-09-02

Notch receptors with hinge domain

#702
20210261668
2021-08-26

PROTEINS BINDING NKG2D, CD16, AND EGFR, CCR4, OR PD-L1

#703
20210261659
2021-08-26

CD79A chimeric antigen receptors

#704
20210260116
2021-08-26

Chimeric antigen receptor-modified NK-92 cells

#705
20210253741
2021-08-19

BISPECIFIC ANTIBODIES

#706
20210253740
2021-08-19

Modified immunoglobulin hinge regions to reduce hemagglutination

#707
20210253728
2021-08-19

Compositions and Methods for Retrieving Tumor-related Antibodies and Antigens

#708
20210253712
2021-08-19

Universal T cells and the method of use thereof

#709
20210252055
2021-08-19

MODIFIED GAMMA DELTA T CELLS AND USES THEREOF

#710
20210246228
2021-08-12

FC-REGION VARIANTS WITH MODIFIED FCRN- AND PROTEIN A-BINDING PROPERTIES

#711
20210246215
2021-08-12

EphA3 directed CAR-T cells for treatment of tumors

#712
20210246207
2021-08-12

Antibodies Comprising Chimeric Constant Domains

#713
20210238310
2021-08-05

COMPOSITIONS AND METHODS RELATED TO ENGINEERED Fc-ANTIGEN BINDING DOMAIN CONSTRUCTS

#714
20210236610
2021-08-05

ALLOGENEIC TUMOR CELL VACCINE

#715
20210230547
2021-07-29

Chimeric antigen receptor-modified NK-92 cells targeting EGFR super-family receptors

#716
20210230301
2021-07-29

DIMERIC PROTEIN WITH TRIPLE MUTATIONS

#717
20210230274
2021-07-29

Anti-PD1 antibodies and their use as therapeutics and diagnostics

#718
20210230246
2021-07-29

USE OF INHIBITORY CHIMERIC RECEPTORS TO PREVENT T CELL-INDUCED BLOOD BRAIN BARRIER DAMAGE

#719
20210221917
2021-07-22

Compositions and methods related to engineered Fc constructs

#720
20210221868
2021-07-22

Anti-BCMA chimeric antigen receptors

#721
20210220404
2021-07-22

CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF

#722
20210207093
2021-07-08

Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene

#723
20210205426
2021-07-08

Immunoprotection of Therapeutic Moieties Using Enhanced Fc Regions

#724
20210198342
2021-07-01

FC-EPSILON CAR (Very imp commercially - in clinical trial)

#725
20210189011
2021-06-24

Dual Variable Region Antibody-Like Binding Proteins Having Cross-Over Binding Region Orientation

#726
20210188974
2021-06-24

Anti-PVRIG antibodies and methods of use

#727
20210188957
2021-06-24

ANTIBODY HALF-MOLECULE, AND METHOD FOR INHIBITING HOMODIMER FORMATION OF ANTIBODY HALF-MOLECULE

#728
20210188947
2021-06-24

Optimized nucleic acid antibody constructs encoding anti-respiratory syncytial virus (RSV) antibodies

#729
20210171998
2021-06-10

Lysine conjugated immunoglobulins

#730
20210171601
2021-06-10

LEUCINE ZIPPER-BASED COMPOSITIONS AND METHODS OF USE

#731
20210170001
2021-06-10

CS1 targeted chimeric antigen receptor-modified T cells

#732
20210161954
2021-06-03

Universal anti-CD22 chimeric antigen receptor engineered immune cells

#733
20210155702
2021-05-27

ANTIBODY-MODIFIED CHIMERIC ANTIGEN RECEPTOR MODIFIED T CELL AND USES THEREOF

#734
20210155699
2021-05-27

ANTIBODY VARIANTS HAVING MODIFICATIONS IN THE CONSTANT REGION

#735
20210147563
2021-05-20

Humanized DR4 antibody gene having apoptosis-inducing activity and dual-acting chimeric antigen receptor T cell or natural killer cell therapeutic agent using same

#736
20210147549
2021-05-20

COMPOSITIONS AND METHODS RELATED TO ENGINEERED Fc-ANTIGEN BINDING DOMAIN CONSTRUCTS TARGETED TO PD-L1

#737
20210145882
2021-05-20

METHODS FOR ADOPTIVE CELL THERAPY TARGETING ROR1

#738
20210139595
2021-05-13

TREATMENT OF CANCER USING A CD33 CHIMERIC ANTIGEN RECEPTOR

#739
20210139590
2021-05-13

FC binding fragments comprising a PD-L1 antigen-binding site

#740
20210139583
2021-05-13

Production of engineered T-cells by sleeping beauty transposon coupled with methotrexate selection

#741
20210139560
2021-05-13

Immunomodulatory fusion proteins

#742
20210130496
2021-05-06

MULTISPECIFIC BINDING PROTEINS TARGETING CEA

#743
20210130470
2021-05-06

Methods of using bispecific molecules having immunoreactivity with PD-1 and CTLA-4

#744
20210130465
2021-05-06

Bispecific antibody construct directed to MUC17 and CD3

#745
20210122825
2021-04-29

HLA-G specific chimeric antigen receptor, nucleic acid, HLA-G specific chimeric antigen receptor expression plasmid, HLA-G specific chimeric antigen receptor expressing cell, use thereof, and pharmaceutical composition for treating cancer

#746
20210122823
2021-04-29

Bispecific antibody and uses thereof

#747
20210115152
2021-04-22

COMPOSITION OF BISPECIFIC ANTIBODIES AND METHOD OF USE THEREOF

#748
20210107998
2021-04-15

Compound targeting IL-23A and B-cell activating factor (BAFF) and uses thereof

#749
20210107976
2021-04-15

Cells expressing chimeric activating receptors and chimeric stimulating receptors and uses thereof

#750
20210107964
2021-04-15

Hinge area and use of same in constructing car skeleton

#751
20210106619
2021-04-15

NK-92 Bone and Brain targeting

#752
20210101995
2021-04-08

General sequence of chimeric antigen receptor, chimeric antigen receptor and an application thereof

#753
20210101978
2021-04-08

CHIMERIC RECEPTORS AND METHODS OF USE THEREOF

#754
20210101954
2021-04-08

Chimeric antibody/T-cell receptor constructs and uses thereof

#755
20210100839
2021-04-08

Universal chimeric antigen receptor T cells specific for CD22

#756
20210095006
2021-04-01

RECOMBINANT IgG Fc MULTIMERS FOR THE TREATMENT OF NEUROMYELITIS OPTICA

#757
20210087295
2021-03-25

Disrupting tumor tissues by targeting fibroblast activation protein (FAP)

#758
20210087279
2021-03-25

REGULATABLE CHIMERIC ANTIGEN RECEPTOR

#759
20210087278
2021-03-25

ANTI-cMET ANTIBODY

#760
20210087271
2021-03-25

FC VARIANTS WITH REDUCED EFFECTOR FUNCTION

#761
20210079102
2021-03-18

COMBINATION THERAPY OF CANCER INVOLVING MULTI-SPECIFIC BINDING PROTEINS THAT ACTIVATE NATURAL KILLER CELLS

#762
20210079098
2021-03-18

PD-L1 -binding molecules comprising Shiga toxin A subunit scaffolds

#763
20210070887
2021-03-11

FLT3L-FC fusion proteins

#764
20210070878
2021-03-11

PSMA and CD3 Bispecific T Cell Engaging Antibody Constructs

#765
20210069319
2021-03-11

Vaccine molecules

#766
20210061887
2021-03-04

FUSION PROTEIN COMPRISING MULTIPLE HINGE SEQUENCES

#767
20210060129
2021-03-04

IgG4 Fc fragment comprising modified hinge region

#768
20210060071
2021-03-04

Chimeric Antigen Receptor T Regulatory Cells for the Treatment of Atherosclerosis

#769
20210060067
2021-03-04

Enhanced immune cells using dual shRNA and composition including the same

#770
20210054409
2021-02-25

Adhesion Receptor Constructs and Uses Thereof in Natural Killer Cell Immunotherapy

#771
20210054099
2021-02-25

Compositions for inhibiting MASP-2 dependent complement activation

#772
20210047435
2021-02-18

Materials and methods for improved single chain variable fragments

#773
20210047422
2021-02-18

Bi-specific anti-CGRP receptor/PAC1 receptor antigen binding proteins and uses thereof

#774
20210046116
2021-02-18

FLT3L-based chimeric proteins

#775
20210040223
2021-02-11

Antibodies to canine interleukin-4 receptor alpha

#776
20210040217
2021-02-11

Chimeric antigen receptors against multiple HLA-G isoforms

#777
20210040197
2021-02-11

Antigen binding molecule formats

#778
20210024615
2021-01-28

CHIMERIC FC RECEPTOR BINDING PROTEINS AND USES THEREOF

#779
20210024613
2021-01-28

Serpin fusion polypeptides and methods of use thereof

#780
20210015865
2021-01-21

CHIMERIC ENGULFMENT RECEPTORS AND USES THEREOF FOR NEURODEGENERATIVE DISEASES

#781
20210009718
2021-01-14

FLT3L-Fc FUSION PROTEINS AND METHODS OF USE

#782
20210009692
2021-01-14

Combination of anti-LAG-3 antibodies and anti-PD-1 antibodies to treat tumors

#783
20210009690
2021-01-14

METHODS AND COMPOSITIONS FOR INHIBITING CD32B EXPRESSING CELLS

#784
20210009689
2021-01-14

METHODS AND COMPOSITIONS FOR INHIBITING CD32B EXPRESSING CELLS

#785
20210009674
2021-01-14

BISPECIFIC ANTIBODIES TO TNF-ALPHA AND IL-1BETA AND USES THEREOF

#786
20210009660
2021-01-14

Recombinant immunoglobulin heavy chains comprising a sortase conjugation loop and conjugates thereof

#787
20210008166
2021-01-14

Methods of treating neutorpenia using G-CSF protein complex

#788
20210002385
2021-01-07

GENETIC ENGINEERING OF NON-HUMAN ANIMALS FOR THE PRODUCTION OF CHIMERIC ANTIBODIES

#789
20210002366
2021-01-07

NOVEL HUMANIZED ANTI-CD19 CHIMERIC ANTIGEN RECEPTOR, ITS NUCELIC ACID SEQUENCE AND ITS PREPARATION

#790
20210002364
2021-01-07

Transgene genetic tags and methods of use

#791
20210002361
2021-01-07

Anti-interleukin-33 antibodies and uses thereof

#792
20210002352
2021-01-07

Serpin fusion polypeptides and methods of use thereof

#793
20210000952
2021-01-07

Anti-TIGIT antibodies, anti-PVRIG antibodies and combinations thereof

#794
20200407466
2020-12-31

Genetic engineering of non-human animals for the production of chimeric antibodies

#795
20200407465
2020-12-31

GENETIC ENGINEERING OF NON-HUMAN ANIMALS FOR THE PRODUCTION OF CHIMERIC ANTIBODIES

#796
20200407464
2020-12-31

Genetic engineering of non-human animals for the production of chimeric antibodies

#797
20200400676
2020-12-24

Articles and methods directed to personalized therapy of cancer

#798
20200399393
2020-12-24

Dimeric antigen receptors

#799
20200399369
2020-12-24

Trispecific binding proteins, methods, and uses thereof

#800
20200399365
2020-12-24

Site-specific antibody-drug conjugates

#801
20200399336
2020-12-24

IL-21 (heterodimeric Fc-fused IL-21) fused to immunoglobulin heavy chain constant region heterodimer (heterodimeric Fc), and pharmaceutical composition comprising same

#802
20200392253
2020-12-17

Method for generating multispecific antibodies from monospecific antibodies

#803
20200385482
2020-12-10

HUMAN MONOCLONAL ANTI-PD-L1 ANTIBODIES AND METHODS OF USE

#804
20200384029
2020-12-10

DUAL CAR EXPRESSING T CELLS INDIVIDUALLY LINKED TO CD28 AND 4-1BB

#805
20200377619
2020-12-03

Genetic engineering of non-human animals for the production of chimeric antibodies

#806
20200370013
2020-11-26

Engineered Expression of Cell Surface and Secreted Sialidase by CAR T Cells for Increased Efficacy in Solid Tumors

#807
20200363420
2020-11-19

ARTICLES AND METHODS DIRECTED TO PERSONALIZED THERAPY OF CANCER

#808
20200362034
2020-11-19

IgG Fc variants for veterinary use

#809
20200354477
2020-11-12

Fluorescein-specific cars exhibiting optimal t cell function against FL-PLE labelled tumors

#810
20200347115
2020-11-05

NOVEL TNF FAMILY LIGAND TRIMER-CONTAINING ANTIGEN BINDING MOLECULES

#811
20200345774
2020-11-05

Engineered phagocytic receptor compositions and methods of use thereof

#812
20200345773
2020-11-05

Engineered phagocytic receptor compositions and methods of use thereof

#813
20200332255
2020-10-22

IMMORTALIZED CAR-T CELLS GENETICALLY MODIFIED TO ELIMINATE T-CELL RECEPTOR AND BETA 2-MICROGLOBULIN EXPRESSION

#814
20200332022
2020-10-22

Inert format

#815
20200317820
2020-10-08

Assembly of bispecific antibodies

#816
20200317783
2020-10-08

BISPECIFIC ANTIBODY

#817
20200317777
2020-10-08

Enhanced chimeric antigen receptors and uses thereof

#818
20200308309
2020-10-01

Method of manufacturing bispecific antibodies, bispecific antibodies and therapeutic use of such antibodies

#819
20200308305
2020-10-01

Chimeric engulfment receptor molecules and methods of use

#820
20200308304
2020-10-01

HINGE MODIFIED ANTIBODY FRAGMENTS AND METHODS OF MAKING

#821
20200308300
2020-10-01

Chimeric antigen receptors targeted to PSCA

#822
20200308288
2020-10-01

Non-antagonistic antibodies directed against the alpha chain of the IL7 receptor extracellular domain and use thereof in cancer treatment

#823
20200308248
2020-10-01

Chimeric Natural Killer Cell Receptors and Method of Using Thereof

#824
20200308238
2020-10-01

Heterodimeric proteins for modulating gamma delta T cells

#825
20200299400
2020-09-24

ANTIBODIES COMPRISING MODIFIED HEAVY CONSTANT REGIONS

#826
20200299371
2020-09-24

PHARMACEUTICAL COMPOSITION COMPRISING PEGYLATED FAB' FRAGMENT OF ANTI-HUMAN NGF ANTIBODY

#827
20200299345
2020-09-24

Engineered opsonin for pathogen detection and treatment

#828
20200297843
2020-09-24

Nanoparticle compositions and methods for immunotherapy

#829
20200291354
2020-09-17

Cell secreted minibodies and uses thereof

#830
20200291087
2020-09-17

Anti-BCMA chimeric antigen receptors

#831
20200291083
2020-09-17

Engineered opsonin for pathogen detection and treatment

#832
20200283541
2020-09-10

Anti-GD2 antibody

#833
20200283524
2020-09-10

Bispecific polypeptide complexes

#834
20200283523
2020-09-10

Bispecific CD3/CD19 polypeptide complexes

#835
20200282021
2020-09-10

GLP-1 FUSION PROTEINS AND USES THEREOF

#836
20200277400
2020-09-03

CHIMERIC ANTIGEN RECEPTOR COMPOSITIONS

#837
20200277395
2020-09-03

TETRAVALENT ANTI-PSGL-1 ANTIBODIES AND USES THEREOF

#838
20200277383
2020-09-03

PROTEINS BINDING NKG2D, CD16 AND A TUMOR-ASSOCIATED ANTIGEN

#839
20200276325
2020-09-03

Immunoconjugates with an intracellularly-cleavable linkage

#840
20200271657
2020-08-27

ARTICLES AND METHODS DIRECTED TO PERSONALIZED THERAPY OF CANCER

#841
20200270363
2020-08-27

ANTIBODY HAVING ENHANCED ACTIVITY, AND METHOD FOR MODIFYING SAME

#842
20200270332
2020-08-27

Means and methods for treating and diagnosing fibrosis or fibrosis-associated diseases

#843
20200268901
2020-08-27

ANTIBODIES COMPRISING MODIFIED HEAVY CONSTANT REGIONS

#844
20200268797
2020-08-27

GAMMA DELTA T CELLS AND USES THEREOF

#845
20200262932
2020-08-20

Heterodimeric antibody Fc-containing proteins and methods for production thereof

#846
20200262926
2020-08-20

Multispecific binding proteins with mutant fab domains

#847
20200262891
2020-08-20

CD33 exon 2 deficient donor stem cells for use with CD33 targeting agents

#848
20200255842
2020-08-13

Long-acting G-CSF for preventing neutropenia or reducing duration of neutropenia

#849
20200247899
2020-08-06

Multispecific antibodies against CD40 and CD137

#850
20200239579
2020-07-30

ANTIBODIES AGAINST PD-L1

#851
20200239568
2020-07-30

Homodimeric protein constructs

#852
20200231700
2020-07-23

PROTEINS BINDING GD2, NKG2D AND CD16

#853
20200231686
2020-07-23

GPRC5D chimeric antigen receptors and cells expressing the same

#854
20200231681
2020-07-23

Anti-c-Met antibody and use thereof

#855
20200231678
2020-07-23

Proteins binding HER2, NKG2D and CD16

#856
20200224162
2020-07-16

Dual chimeric antigen receptor-t cell which can be regulated, construction method therefor and use thereof

#857
20200223939
2020-07-16

Multispecific antibody analogs comprising a common light chain, and methods of their preparation and use

#858
20200223933
2020-07-16

Antigen binding proteins binding to 5T4 and 4-1BB and related compositions and methods

#859
20200216546
2020-07-09

Human antigen binding proteins that bind β-klotho, FGF receptors and complexes thereof

#860
20200216544
2020-07-09

PROTEINS BINDING NKG2D, CD16, AND EGFR, HLA-E, CCR4, OR PD-L1

#861
20200216535
2020-07-09

Anti-PD1 antibodies and their use as therapeutics and diagnostics

#862
20200216505
2020-07-09

Heterodimeric proteins for modulating gamma delta T cells

#863
20200207855
2020-07-02

Combination of a Treg depleting anti-4-1BB antibody and anti-PD1 antibody

#864
20200207852
2020-07-02

T CELLS EXPRESSING A CHIMERIC ANTIGEN RECEPTOR

#865
20200207851
2020-07-02

Trifunctional molecule and application thereof

#866
20200199229
2020-06-25

Humanized or chimeric CD3 antibodies

#867
20200197485
2020-06-25

Methods of use of soluble CD24 for treating immune related adverse events in cancer therapies

#868
20200181288
2020-06-11

Cell engaging binding molecules

#869
20200181286
2020-06-11

Genetic engineering of non-human animals for the production of chimeric antibodies

#870
20200181285
2020-06-11

Genetic engineering of non-human animals for the production of chimeric antibodies

#871
20200181269
2020-06-11

OCTS technology-based pancreatic cancer and malignant mesothelioma CAR-T therapeutic vector, construction method therefor, and use thereof

#872
20200181268
2020-06-11

Malignant glioma CAR-T therapeutic vector based on OCTS technology, and construction method and application thereof

#873
20200181235
2020-06-11

METHODS OF USE OF SOLUBLE CD24 FOR NEUROPROTECTION AND REMYELINATION

#874
20200181231
2020-06-11

SPD-1 variant# FC fusion proteins

#875
20200181227
2020-06-11

Car T-cells recognizing cancer-specific IL 13Ra2

#876
20200172630
2020-06-04

Antibodies and chimeric antigen receptors specific for CD19

#877
20200172622
2020-06-04

Bispecific binding proteins and uses thereof

#878
20200172619
2020-06-04

Heterodimerizing Ig domains

#879
20200172613
2020-06-04

Immunologic effector cell of targeted CLD18A2, and preparation method and use thereof

#880
20200165346
2020-05-28

CD123 binding proteins and related compositions and methods

#881
20200165344
2020-05-28

PROTEINS BINDING NKG2D, CD16 AND FLT3

#882
20200157239
2020-05-21

REMOVAL OF TARGET CELLS BY CIRCULATING VIRUS-SPECIFIC CYTOTOXIC T-CELLS USING MHC CLASS I COMPRISING COMPLEXES

#883
20200157226
2020-05-21

PROTEINS BINDING NKG2D, CD16 AND A TUMOR-ASSOCIATED ANTIGEN

#884
20200157204
2020-05-21

Antibodies of the class IGG4

#885
20200157174
2020-05-21

PROTEINS BINDING NKG2D, CD16 AND ROR1 OR ROR2

#886
20200157172
2020-05-21

NOVEL THERAPEUTIC ENZYME FUSION PROTEIN AND USE THEREOF

#887
20200148779
2020-05-14

MODIFIED IgG1 Fc DOMAINS AND ANTI-CD40 DOMAIN ANTIBODY FUSIONS THEREWITH

#888
20200148769
2020-05-14

Anti-PVRIG antibodies and methods of use

#889
20200140560
2020-05-07

PROTEASE BASED SWITCH CHIMERIC ANTIGEN RECEPTORS FOR SAFER CELL IMMUNOTHERAPY

#890
20200140552
2020-05-07

Trispecific anti-CD38, anti-CD28, and anti-CD3 binding proteins and methods of use for treating viral infection

#891
20200140522
2020-05-07

ApoC-II mimetic peptides

#892
20200140512
2020-05-07

PD-1 targeted IL-15/IL-15RALPHA fc fusion proteins and uses in combination therapies thereof

#893
20200138969
2020-05-07

Light chain variable regions

#894
20200131262
2020-04-30

Targeting modules for universal chimeric antigen receptor expressing immune cells and use in the treatment of cancer infections and autoimmune disorders

#895
20200131258
2020-04-30

scFv-Fc dimers that bind transforming growth factor-β1 with high affinity, avidity and specificity

#896
20200131244
2020-04-30

Truncated NKG2D chimeric receptors and uses thereof in natural killer cell immunotherapy

#897
20200123259
2020-04-23

Bispecific heterodimeric fusion proteins containing IL-15-IL-15Ralpha Fc-fusion proteins and immune checkpoint antibody fragments

#898
20200123233
2020-04-23

Amino acid sequences directed against envelope proteins of a virus and polypeptides comprising the same for the treatment of viral diseases

#899
20200123224
2020-04-23

Methods of exogenous drug activation of chemical-induced signaling complexes expressed in engineered cells in vitro and in vivo

#900
20200123214
2020-04-23

CSF1R-based chimeric proteins