97300 ⎘
Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen Agonist effect on antigen
COMBINATION THERAPY OF TUMOR TARGETED ICOS AGONISTS WITH T-CELL BISPECIFIC MOLECULES
#602ANTIBODIES COMPRISING MODIFIED HEAVY CONSTANT REGIONS
#603ANTIBODIES BINDING TO HUMAN AND CYNOMOLGUS CD3 EPSILON
#604Treatment of cancer with anti-GITR agonist antibodies
#605ANTIBODY SUBSTITUTING FOR FUNCTION OF BLOOD COAGULATION FACTOR VIII
#606ANTI-TREM2 ANTIBODIES AND METHODS OF USE THEREOF
#607AntiPlexin A1 agonist antibody
#608Bispecific antibodies against HER2 and CD3
#609Anti-coagulation factor XI antibodies
#610Vectors comprising nucleic acids encoding anti-OX40 antibodies
#611Humanized monoclonal antibodies that target VE-PTP (HPTP-beta)
#612ANTIBODIES COMPRISING MODIFIED HEAVY CONSTANT REGIONS
#613APOPTOTIC CELL-MEDIATED INDUCTION OF ANTIGEN SPECIFIC REGULATORY T-CELLS FOR THE THERAPY OF AUTOIMMUNE DISEASES IN ANIMALS AND HUMANS
#614Anti-coagulation factor XI antibodies
#615B7-H4 antibodies and methods of use thereof
#616HUMAN IMMUNE THERAPIES USING A CD27 AGONIST ALONE OR IN COMBINATION WITH OTHER IMMUNE MODULATORS
#617Humanized antibodies with ultralong complementary determining regions
#618Fn14 Binding Proteins and Uses Thereof
#619AGONIST FUSION PROTEIN FOR CD40 AND OX40 AND USES THEREOF
#620Agonistic CD40 antibodies
#621BTLA agonist antibodies and uses thereof
#622Humanized monoclonal antibodies that target VE-PTP (HPTP-β)
#623TREATMENT OF OCULAR DISEASE
#624FC engineered anti-TNFR superfamily member antibodies having enhanced agonistic activity and methods of using them
#625Antagonists targeting the TGF-β pathway
#626Antigen binding proteins binding to 5T4 and 4-1BB and related compositions and methods
#627Markers of acute myeloid leukemia stem cells
#628Adenovirus armed with bispecific T cell activator
#629Human antigen binding proteins that bind β-klotho, FGF receptors and complexes thereof
#630Anti-TLR4 antibodies and uses thereof
#631Combination of a Treg depleting anti-4-1BB antibody and anti-PD1 antibody
#632Trifunctional molecule and application thereof
#633IDENTIFICATION OF VSIG8 AS THE PUTATIVE VISTA RECEPTOR (V-R) AND USE THEREOF TO PRODUCE VISTA/VSIG8 AGONISTS AND ANTAGONISTS
#634PDL1-binding proteins
#635WNT SIGNALING AGONIST MOLECULES
#636WNT SIGNALING AGONIST MOLECULES
#637Tumor-targeted agonistic CD28 antigen binding molecules
#638Humanized or chimeric CD3 antibodies
#639COMBINATION THERAPY WITH AN ANTI-ANG2 ANTIBODY AND A CD40 AGONIST
#640Polypeptides
#641Immunotherapy using antibodies that bind programmed death ligand-1 (PD-L1)
#642COMBINATION THERAPY WITH ICOS AGONIST AND OX40 AGONIST TO TREAT CANCER
#643COMBINATION THERAPY
#644Anti-CD3-binding domains and antibodies comprising them, and methods for their generation and use
#645Anti-PD-1 antibodies
#646INTERLEUKIN-2 IMMUNOCONJUGATE, A CD40 AGONIST, AND OPTIONALLY A PD-1 AXIS BINDING ANTAGONIST FOR USE IN METHODS OF TREATING CANCER
#647Binding molecule activating FXII
#648ANTI-OX40 ANTIBODIES AND THEIR USES
#649Polypeptide variants and uses thereof
#650Anti-human 4-1BB antibodies and uses thereof
#651LIVE AND IN-VIVO TUMOR SPECIFIC CANCER VACCINE SYSTEM DEVELOPED BY CO-ADMINISTRATION OF EITHER AT LEAST TWO OR ALL THREE OF THE FOLLOWING COMPONENTS SUCH AS TUMOR CELLS, AN ONCOLYTIC VIRUS VECTOR WITH TRANSGENIC EXPRESSION OF GM-CSF AND AN IMMUNE CHECKPOINT MODULATOR
#652CD123 binding proteins and related compositions and methods
#653Binding agonist for treatment of neurological and other disorders
#654Bispecific antibodies which bind PD-L1 and GITR
#655Resolvin mimetic antibodies and uses thereof
#656METHODS AND COMPOSITIONS FOR LIGAND DIRECTED ANTIBODY DESIGN
#657Anti-ALK antibodies and methods for use thereof
#658Anti-CD137 antibodies
#659Bispecific antibodies for factor IX and factor X
#660MODIFIED IgG1 Fc DOMAINS AND ANTI-CD40 DOMAIN ANTIBODY FUSIONS THEREWITH
#661Inducible monovalent antigen binding protein
#662Oncolytic virus and method
#663Anti-OX40 antibody and use thereof
#664TREM2 stabilizing antibodies
#665Anti-claudin-2 monoclonal antibody
#666Monoclonal Antibodies to Programmed Death 1 (PD-1)
#667Humanized antibodies
#668FcgammaRIIB-Specific Antibodies and Methods of Use Thereof
#669Anti-TREM1 antibodies and methods of use thereof
#670MEDICAL TREATMENT METHOD WITH ADMINISTRATION OF DENDRITIC CELLS
#671PD-L1 expressing hematopoietic stem cells and uses
#672Engraftment of stem cells with a combination of an agent that targets stem cells and modulation of immunoregulatory signaling
#673Anti-NPR1 antibodies and uses thereof
#674BISPECIFIC ANTIBODIES
#675ICOS binding proteins
#676Methods of treating cancer with placenta growth factor peptide linked to immunotherapeutic antibodies
#677Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR) and uses thereof
#678Single domain antibodies targeting CD1d
#679Anti-CD3 antibodies
#680Antibodies specific for hyperphosphorylated tau and methods of use thereof
#681NOTCH3 agonist compositions and methods for treating small vessel diseases
#682Anti-IL1RAP antibodies
#683ANTIBODY HEAVY CHAIN VARIABLE DOMAINS TARGETING THE NKG2D RECEPTOR
#684Anti-TIGIT antigen-binding proteins and methods of use thereof
#685Targeted chimeric proteins and uses thereof
#686HUMANIZED ANTI-CD40 ANTIBODIES
#687CD200R agonist antibodies and uses thereof
#688Vista modulators for diagnosis and treatment of cancer
#689PD-L1 expressing hematopoietic stem cells and uses
#690T CELL BALANCE GENE EXPRESSION, COMPOSITIONS OF MATTERS AND METHODS OF USE THEREOF
#691Agonistic tumor necrosis factor (TNF) receptor binding agents
#692Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR) and uses thereof
#693Antibodies and methods of use thereof
#694ANTIBODIES TO CD40 WITH ENHANCED AGONIST ACTIVITY
#695Anti-LAG-3 antibodies and uses thereof
#696Anti-LILRB3 antibodies and methods of use thereof
#697Bispecific binding molecules that are capable of binding CD137 and tumor antigens, and uses thereof
#698HUMAN MONOCLONAL ANTIBODIES TO PROGRAMMED DEATH LIGAND 1 (PD-L1)
#699Anti-transferrin receptor antibodies with tailored affinity
#700Antigen binding molecules and methods of use thereof
#701Anti-OX40 antibodies and their uses
#702BISPECIFIC ANTIBODY AGAINST OX40 AND CTLA-4
#703Tissue-specific Wnt signal enhancing molecules and uses thereof
#704AGONIST ANTIBODIES THAT BIND HUMAN CD137 AND USES THEREOF
#705Anti-PD-1 antibodies and their uses
#706Anti-CD40 antibodies
#707Drug delivery compositions and uses thereof
#708Anti-ICOS agonist antibodies and uses thereof
#709Protein binding domains stabilizing functional conformational states of GPCRS and uses thereof
#710USE OF ANTI-PD-1 ANTIBODY IN COMBINATION WITH ANTI-CD27 ANTIBODY IN CANCER TREATMENT
#711PROTEINS BINDING PSMA, NKG2D AND CD16
#712COMPOSITIONS AND METHODS FOR MODULATING CELL SIGNALING
#713MONOCLONAL ANTIBODIES ACTIVATING CD40 AND USES THEREOF
#714Binding molecules that bind CD137 and PD-L1
#715IMMUNOMODULATORY ANTIBODIES
#716Anti-TrkB agonist antibodies binding to D5 domain of TrkB and methods of promoting neuronal survival in motor neuron injury, stroke or glaucoma
#717Anti-vista antibodies and fragments
#718B7-DC BINDING ANTIBODY
#719Anti-CD40 antibody
#720Dysfunctional antigen-specific CD8T cells in the tumor microenvironment
#721Compositions and methods for treating cancer
#722PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF
#723Protein binding domains stabilizing functional conformational states of GPCRs and uses thereof
#724PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF
#725PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF
#726Oncofetal antigen binding proteins and related compositions and methods
#727Drug delivery compositions and uses thereof
#728Fusion Polypeptides Capable Of Activating Receptors
#729BINDING AGENTS
#730COMPOSITIONS AND METHODS FOR MODULATING IMMUNE RESPONSES
#731Anti-OX40 antibodies and anti-GITR antibodies
#732TRAILshort antibody and methods of use
#733Methods of treating cancer in a subject having elevated ICOS and/or T-bet levels of CD+4 cells by administering an ICOS agonist
#734DISTINGUISHING ANTAGONISTIC AND AGONISTIC ANTI B7-H1 ANTIBODIES
#735CHIMERIC RECEPTORS, BIOSENSOR HOST CELLS AND METHODS/USES THEREOF
#736ANTIBODY SUBSTITUTING FOR FUNCTION OF BLOOD COAGULATION FACTOR VIII
#737Anti-SIRPA antibodies and methods of use thereof
#738Methods of treating an osteolytic tumor and spinal cord injury by administering connexin (Cx) 43 hemichannel-binding antibodies
#739Antagonizing CD73 antibody
#740Anti-CD137 antibodies and uses thereof
#741Anti-CD137 antibodies and uses thereof
#742Nucleic acids encoding anti-OX40 antibodies
#743Antibodies directed against ICOS and uses thereof
#744NOVEL IGFR_LIKE 2 RECEPTOR AND USES THEREOF
#745MULTIMERIC CD40 BINDING MOLECULES AND USES THEREOF
#746MULTIMERIC CD137/4-1BB BINDING MOLECULES AND USES THEREOF
#747Anti-leukocyte-associated immunoglobulin-like receptor 1 (LAIR1) monoclonal antibodies and method of use thereof to treat cancer
#748MULTIMERIC OX40 BINDING MOLECULES AND USES THEREOF
#749MULTISPECIFIC POLYPEPTIDE CONSTRUCTS HAVING CONSTRAINED CD3 BINDING AND RELATED METHODS AND USES
#750IFN-gamma-inducible regulatory T cell convertible anti-cancer (IRTCA) antibody and uses thereof
#751Anti-FGFR3 antibodies and methods using same
#752IGF-1R antibody and its use as addressing vehicle for the treatment of cancer
#753Anti-human VISTA antibodies and use thereof
#754ANTI-TREM2 ANTIBODIES AND METHODS OF USE THEREOF
#755Methods for cancer therapy using isolated NTB-A ectodomain polypeptides
#756Agonistic antibodies that bind CD40
#757MULTI-SPECIFIC ANTIGEN-BINDING MOLECULE HAVING ALTERNATIVE FUNCTION TO FUNCTION OF BLOOD COAGULATION FACTOR VIII
#758Anti-DR5 antibodies and methods of use thereof
#759Anti-MET antibodies and uses thereof
#760Methods of treatment using anti-c-met antibodies
#761Anti-TIGIT antibodies
#762Antibodies directed against ICOS and uses thereof
#763Anti-TREM2 antibodies and methods of use thereof
#764Multivalent and multispecific DR5-binding fusion proteins and methods of treating neoplasms
#765Anti-GITR antibodies and methods of use thereof
#766Methods of treatment using a leptin receptor agonist antibody
#767Anti-ICOS agonist antibodies and uses thereof
#7684-1BB binding proteins and uses thereof
#769Anti-OX40 antibodies
#770Method of treating cancer in a patient by administering an antibody which binds colony stimulating factor-1 receptor (CSF-1R)
#771Antibodies specific for hyperphosphorylated tau and methods of use thereof
#772Antibodies specific for hyperphosphorylated tau and methods of use thereof
#773Anti-TIE2 antibodies and uses thereof
#774Antigen-binding polypeptides directed against CD38
#775POLYPEPTIDE VARIANTS AND USES THEREOF
#776Anti-TIM-3 antibodies and compositions
#777Anti-SIRP-alpha antibodies and methods of use thereof
#778PD-1 agonist antibodies and uses thereof
#779Methods of treating an IGFBP-3R expressing cancer using anti-IGFBP-3R antibodies
#780Agonist antibodies that bind human CD137 and uses thereof
#781Sequence of antibody heavy chain constant region for enhancing agonistic antibody activity
#782Multivalent and multispecific OX40-binding fusion proteins
#783Immunoglobulins binding human Vγ9Vδ2 T cell receptors
#784Dual receptor antagonistic antigen-binding proteins and uses thereof
#785Anti-ICOS and anti-PD-1 antibody combination therapy
#786Optimization of antibodies that bind lymphocyte activation gene-3 (LAG-3), and uses thereof
#787Nucleic acids encoding an anti-CD40 antibody
#788Antigen binding proteins that bind to a complex comprising β-Klotho and an FGF receptor
#789Anti-MERTK agonistic antibodies and uses thereof
#790Adenovirus armed with bispecific T cell engager
#791IFN-γ-inducible regulatory T cell convertible anti-cancer (IRTCA) antibody and uses thereof
#792Methods and compositions for treating inflammatory or autoimmune diseases or conditions using calcitonin receptor activators
#793Non-cytotoxic modified cells and use thereof
#794Agents that engage antigen-presenting cells through dendritic cell asialoglycoprotein receptor (DC-ASGPR)
#795Anti-LAG-3 antibodies and uses thereof
#796Agonist antibodies that bind human CD137 and uses thereof
#797Platforms and methods for optimizing host antigen presentation and host antitumor and antipathogen immunity
#798Anti-PD-L1 antibodies and methods of use
#799BISPECIFIC ANTIBODIES WITH TETRAVALENCY FOR A COSTIMULATORY TNF RECEPTOR
#800ANTI- EGFR CONFORMATIONAL SINGLE DOMAIN ANTIBODIES AND USES THEREOF
#801Humanized Anti-CD134 (OX40) Antibodies And Uses Thereof
#802ANTI-DEATH RECEPTOR ANTIBODIES AND METHODS OF USE THEREOF
#803Antibodies for Siglec-15 and methods of use thereof
#804Anti-CD277 antibodies
#805Oncolytic group B adenovirus expressing a stroma-targeted bispecific t-cell engager
#806Anti-4-1BB antibodies and their uses
#807Identification of VSIG3/VISTA as a novel immune checkpoint and use thereof for immunotherapy
#808Methods of treating autoimmune disease or chronic inflammation with antibodies that bind and block triggering receptor expressed on myeloid cells-1 (TREM-1)
#809FACTOR H POTENTIATING ANTIBODIES AND USES THEREOF
#810Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
#811Bispecific antigen binding molecules that bind leptin receptor and/or GP130, and methods of use thereof
#812Broadly cross-reactive HIV-1-specific antibodies for prevention and treatment of HIV
#813Retroviral and lentiviral vectors
#814Host cell comprising nucleic acids encoding bispecific antibodies binding to beta-klotho and fibroblast growth factor receptor 1 and antibody production
#815Anti-OX40 binding proteins
#816TrkB agonist antibodies and methods for treating an ocular degenerative disorder characterized by degeneration of retinal ganglion cells (RGCs)
#817Fusion protein comprising apelin and an anti-APLNR antibody
#818Anti-ICOS agonist antibodies and uses thereof
#819NOVEL BISPECIFIC POLYPEPTIDES AGAINST CD137
#820CANCER AND B-CELL RELATED DISEASE THERAPY
#821COMBINATION THERAPY COMPRISING OX40 BINDING AGONISTS AND TIGIT INHIBITORS
#822Variant antibodies that bind OX40
#823Therapeutic combinations comprising anti-FOLR1 immunoconjugates
#824Bispecific Antibodies Directed Against OX40 and a Tumor-Associated Antigen
#825Antibody therapeutics that bind CD137
#826Anti-TrkB monoclonal antibodies and methods of use
#827SP35 Antibodies And Uses Thereof
#828Anti-LAG-3 antibodies
#829Drug delivery compositions and uses thereof
#830Heterodimeric immunoglobulins
#831RNA containing composition for treatment of tumor diseases
#832REGULATORS OF ANAPLASTIC LYMPHOMA KINASE AND USES THEREOF
#833ANTI-DR5 ANTIBODIES AND METHODS OF USE THEREOF
#834C3D cellular and acellular vaccines for the prevention and treatment of cancer
#835Combining CD27 agonists and immune checkpoint inhibition for immune stimulation
#836AGONISTIC ANTI-TUMOR NECROSIS FACTOR RECEPTOR 2 ANTIBODIES
#837Anti-SIRPa antibodies and their therapeutic applications
#838THERAPEUTIC AGENT FOR SOLID CANCER
#839Methods for selective expansion of γδ T-cell populations and compositions thereof
#840Compositions and methods for treating pancreatitis and pain with death receptor agonists
#841ANTI-TIGIT ANTIBODIES AND METHODS OF USE
#842T cell recruiting polypeptides based on TCR alpha/beta reactivity
#843ANTIBODY SUBSTITUTING FOR FUNCTION OF BLOOD COAGULATION FACTOR VIII
#844Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS
#845IL-21 agonist antibodies and methods of treatment using same
#846Methods Of Identifying Anti-Inflammatory Compounds
#847Immunological reagents
#848Beta klotho-binding proteins and methods of use thereof
#849Anti-OX40 antibodies and methods of using the same
#850IL-17A/F HETEROLOGOUS POLYPEPTIDES AND THERAPEUTIC USES THEREOF
#851PD-L1 expressing hematopoietic stem cells and uses
#852STROMAL GENE SIGNATURES FOR DIAGNOSIS AND USE IN IMMUNOTHERAPY
#853B7-H4 antibodies and methods of use thereof
#854Method of treating cancer with a biomaterial and a toll-like receptor agonist
#855Methods of treating ocular conditions by administering humanized monoclonal antibodies that target VE-PTP (HPTP-beta)
#856Humanized monoclonal antibodies that target protein tyrosine phosphatase-beta (HPTP-β/VE-PTP)
#857Antiviral immunotherapy by membrane receptor ligation
#858Anti-ICOS agonist antibodies and uses thereof
#859Compositions and methods for regulating erythropoiesis
#860Methods of treatment of CD123 overexpressing disorders
#861IMMUNOGLOBULIN VARIANTS AND USES THEREOF
#862Anti-human 4-1BB antibodies and uses thereof
#863Nucleic acid molecules encoding anti-CD40 antibodies
#864Humanized Anti-HLA-DR Antibodies
#865Methods of treating cancer using an IL-21 agonist
#866Antibody peptide conjugates that have agonist activity at both the glucagon and glucagon-like peptide 1 receptors
#867Antibodies specific for DR5 and methods of use
#868Anti-GITR antibodies and methods of use thereof
#869FULLY HUMAN ANTIBODIES AGAINST HUMAN 4-1BB
#870COMBINATION THERAPY COMPRISING ANTI-ANGIOGENESIS AGENTS AND OX40 BINDING AGONISTS
#871Highly potent antibodies binding to death receptor 4
#872Immunological reagents
#873Anti-Siglec-9 antibodies and methods of use thereof
#874Fc γ RIII binding fibronectin type III domains, their conjugates and multispecific molecules comprising them
#875Agonist antibodies that bind human CD137 and uses thereof
#876Multispecific NK engager protein
#877Anti-CD137 molecules and use thereof
#878RNA containing composition for treatment of tumor diseases
#879Protein binding domains stabilizing functional conformational states of GPCRs and uses thereof
#880Multispecific NK engager protein
#881Engineered antibody Fc variants for enhanced serum half life
#882Method for treating pathological angiogenesis by administering an antibody that inhibits APLNR
#883PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF
#884FGF21 mimetic antibodies and uses thereof
#885METHODS OF SCREENING FOR MULTISPECIFIC ANTIBODIES
#886Anti-TREM2 antibodies and methods of use thereof
#887Compositions and methods for detecting, treating and preventing diseases and disorders
#888COMBINATION OF AN OX40 AGONIST AND A 4-1BB AGONIST MONOCLONAL ANTIBODY FOR TREATING CANCER
#889Combination Therapies Employing GITR Binding Molecules
#890Therapeutic and diagnostic methods for autism spectrum disorders and other conditions
#891Methods for inducing or enhancing an immune response by administering agonistic glucocorticoid-induced TNFR-family-related receptor (GITR) antibodies
#892ANTIBODIES THAT BIND HUMAN PROTEIN TYROSINE PHOSPHATASE beta (HPTPbeta) AND USES THEREOF
#893Oncofetal antigen binding proteins and related compositions and methods
#894Antibodies binding LAG-3 and uses thereof
#895Agonist antibodies that bind human CD137 and uses thereof
#896Targeting WSB1 and pVHL to treat cancer
#897Multispecific polypeptide constructs having constrained CD3 binding and methods of using the same
#898Binding agents
#899Anti-GITR antibodies and methods of use thereof
#900ANTI-TREM2 ANTIBODIES AND METHODS OF USE THEREOF