ClassID:

97300

C07K2317/75 - page 3 - CPC Classification

Classification description:

Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen Agonist effect on antigen

Recent Application in this class:
#601
20200306373
2020-10-01

COMBINATION THERAPY OF TUMOR TARGETED ICOS AGONISTS WITH T-CELL BISPECIFIC MOLECULES

#602
20200299400
2020-09-24

ANTIBODIES COMPRISING MODIFIED HEAVY CONSTANT REGIONS

#603
20200299385
2020-09-24

ANTIBODIES BINDING TO HUMAN AND CYNOMOLGUS CD3 EPSILON

#604
20200291122
2020-09-17

Treatment of cancer with anti-GITR agonist antibodies

#605
20200277402
2020-09-03

ANTIBODY SUBSTITUTING FOR FUNCTION OF BLOOD COAGULATION FACTOR VIII

#606
20200277373
2020-09-03

ANTI-TREM2 ANTIBODIES AND METHODS OF USE THEREOF

#607
20200276302
2020-09-03

AntiPlexin A1 agonist antibody

#608
20200270366
2020-08-27

Bispecific antibodies against HER2 and CD3

#609
20200270364
2020-08-27

Anti-coagulation factor XI antibodies

#610
20200270356
2020-08-27

Vectors comprising nucleic acids encoding anti-OX40 antibodies

#611
20200270342
2020-08-27

Humanized monoclonal antibodies that target VE-PTP (HPTP-beta)

#612
20200268901
2020-08-27

ANTIBODIES COMPRISING MODIFIED HEAVY CONSTANT REGIONS

#613
20200261576
2020-08-20

APOPTOTIC CELL-MEDIATED INDUCTION OF ANTIGEN SPECIFIC REGULATORY T-CELLS FOR THE THERAPY OF AUTOIMMUNE DISEASES IN ANIMALS AND HUMANS

#614
20200255542
2020-08-13

Anti-coagulation factor XI antibodies

#615
20200255528
2020-08-13

B7-H4 antibodies and methods of use thereof

#616
20200247898
2020-08-06

HUMAN IMMUNE THERAPIES USING A CD27 AGONIST ALONE OR IN COMBINATION WITH OTHER IMMUNE MODULATORS

#617
20200239599
2020-07-30

Humanized antibodies with ultralong complementary determining regions

#618
20200239586
2020-07-30

Fn14 Binding Proteins and Uses Thereof

#619
20200239584
2020-07-30

AGONIST FUSION PROTEIN FOR CD40 AND OX40 AND USES THEREOF

#620
20200239583
2020-07-30

Agonistic CD40 antibodies

#621
20200239578
2020-07-30

BTLA agonist antibodies and uses thereof

#622
20200239567
2020-07-30

Humanized monoclonal antibodies that target VE-PTP (HPTP-β)

#623
20200231703
2020-07-23

TREATMENT OF OCULAR DISEASE

#624
20200231693
2020-07-23

FC engineered anti-TNFR superfamily member antibodies having enhanced agonistic activity and methods of using them

#625
20200231665
2020-07-23

Antagonists targeting the TGF-β pathway

#626
20200223933
2020-07-16

Antigen binding proteins binding to 5T4 and 4-1BB and related compositions and methods

#627
20200223922
2020-07-16

Markers of acute myeloid leukemia stem cells

#628
20200216859
2020-07-09

Adenovirus armed with bispecific T cell activator

#629
20200216546
2020-07-09

Human antigen binding proteins that bind β-klotho, FGF receptors and complexes thereof

#630
20200207866
2020-07-02

Anti-TLR4 antibodies and uses thereof

#631
20200207855
2020-07-02

Combination of a Treg depleting anti-4-1BB antibody and anti-PD1 antibody

#632
20200207851
2020-07-02

Trifunctional molecule and application thereof

#633
20200199254
2020-06-25

IDENTIFICATION OF VSIG8 AS THE PUTATIVE VISTA RECEPTOR (V-R) AND USE THEREOF TO PRODUCE VISTA/VSIG8 AGONISTS AND ANTAGONISTS

#634
20200199243
2020-06-25

PDL1-binding proteins

#635
20200199238
2020-06-25

WNT SIGNALING AGONIST MOLECULES

#636
20200199237
2020-06-25

WNT SIGNALING AGONIST MOLECULES

#637
20200199234
2020-06-25

Tumor-targeted agonistic CD28 antigen binding molecules

#638
20200199229
2020-06-25

Humanized or chimeric CD3 antibodies

#639
20200199215
2020-06-25

COMBINATION THERAPY WITH AN ANTI-ANG2 ANTIBODY AND A CD40 AGONIST

#640
20200190208
2020-06-18

Polypeptides

#641
20200190197
2020-06-18

Immunotherapy using antibodies that bind programmed death ligand-1 (PD-L1)

#642
20200190195
2020-06-18

COMBINATION THERAPY WITH ICOS AGONIST AND OX40 AGONIST TO TREAT CANCER

#643
20200190194
2020-06-18

COMBINATION THERAPY

#644
20200190189
2020-06-18

Anti-CD3-binding domains and antibodies comprising them, and methods for their generation and use

#645
20200190187
2020-06-18

Anti-PD-1 antibodies

#646
20200188526
2020-06-18

INTERLEUKIN-2 IMMUNOCONJUGATE, A CD40 AGONIST, AND OPTIONALLY A PD-1 AXIS BINDING ANTAGONIST FOR USE IN METHODS OF TREATING CANCER

#647
20200182890
2020-06-11

Binding molecule activating FXII

#648
20200181282
2020-06-11

ANTI-OX40 ANTIBODIES AND THEIR USES

#649
20200181277
2020-06-11

Polypeptide variants and uses thereof

#650
20200172626
2020-06-04

Anti-human 4-1BB antibodies and uses thereof

#651
20200171151
2020-06-04

LIVE AND IN-VIVO TUMOR SPECIFIC CANCER VACCINE SYSTEM DEVELOPED BY CO-ADMINISTRATION OF EITHER AT LEAST TWO OR ALL THREE OF THE FOLLOWING COMPONENTS SUCH AS TUMOR CELLS, AN ONCOLYTIC VIRUS VECTOR WITH TRANSGENIC EXPRESSION OF GM-CSF AND AN IMMUNE CHECKPOINT MODULATOR

#652
20200165346
2020-05-28

CD123 binding proteins and related compositions and methods

#653
20200165345
2020-05-28

Binding agonist for treatment of neurological and other disorders

#654
20200165341
2020-05-28

Bispecific antibodies which bind PD-L1 and GITR

#655
20200163922
2020-05-28

Resolvin mimetic antibodies and uses thereof

#656
20200157529
2020-05-21

METHODS AND COMPOSITIONS FOR LIGAND DIRECTED ANTIBODY DESIGN

#657
20200157236
2020-05-21

Anti-ALK antibodies and methods for use thereof

#658
20200157234
2020-05-21

Anti-CD137 antibodies

#659
20200148787
2020-05-14

Bispecific antibodies for factor IX and factor X

#660
20200148779
2020-05-14

MODIFIED IgG1 Fc DOMAINS AND ANTI-CD40 DOMAIN ANTIBODY FUSIONS THEREWITH

#661
20200148771
2020-05-14

Inducible monovalent antigen binding protein

#662
20200140563
2020-05-07

Oncolytic virus and method

#663
20200140562
2020-05-07

Anti-OX40 antibody and use thereof

#664
20200140545
2020-05-07

TREM2 stabilizing antibodies

#665
20200140542
2020-05-07

Anti-claudin-2 monoclonal antibody

#666
20200138945
2020-05-07

Monoclonal Antibodies to Programmed Death 1 (PD-1)

#667
20200138922
2020-05-07

Humanized antibodies

#668
20200131265
2020-04-30

FcgammaRIIB-Specific Antibodies and Methods of Use Thereof

#669
20200131264
2020-04-30

Anti-TREM1 antibodies and methods of use thereof

#670
20200129603
2020-04-30

MEDICAL TREATMENT METHOD WITH ADMINISTRATION OF DENDRITIC CELLS

#671
20200129559
2020-04-30

PD-L1 expressing hematopoietic stem cells and uses

#672
20200129557
2020-04-30

Engraftment of stem cells with a combination of an agent that targets stem cells and modulation of immunoregulatory signaling

#673
20200123263
2020-04-23

Anti-NPR1 antibodies and uses thereof

#674
20200123260
2020-04-23

BISPECIFIC ANTIBODIES

#675
20200123257
2020-04-23

ICOS binding proteins

#676
20200123228
2020-04-23

Methods of treating cancer with placenta growth factor peptide linked to immunotherapeutic antibodies

#677
20200115463
2020-04-16

Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR) and uses thereof

#678
20200115450
2020-04-16

Single domain antibodies targeting CD1d

#679
20200115449
2020-04-16

Anti-CD3 antibodies

#680
20200109192
2020-04-09

Antibodies specific for hyperphosphorylated tau and methods of use thereof

#681
20200102384
2020-04-02

NOTCH3 agonist compositions and methods for treating small vessel diseases

#682
20200095328
2020-03-26

Anti-IL1RAP antibodies

#683
20200095327
2020-03-26

ANTIBODY HEAVY CHAIN VARIABLE DOMAINS TARGETING THE NKG2D RECEPTOR

#684
20200095324
2020-03-26

Anti-TIGIT antigen-binding proteins and methods of use thereof

#685
20200087411
2020-03-19

Targeted chimeric proteins and uses thereof

#686
20200087410
2020-03-19

HUMANIZED ANTI-CD40 ANTIBODIES

#687
20200087395
2020-03-19

CD200R agonist antibodies and uses thereof

#688
20200085947
2020-03-19

Vista modulators for diagnosis and treatment of cancer

#689
20200085878
2020-03-19

PD-L1 expressing hematopoietic stem cells and uses

#690
20200081017
2020-03-12

T CELL BALANCE GENE EXPRESSION, COMPOSITIONS OF MATTERS AND METHODS OF USE THEREOF

#691
20200079866
2020-03-12

Agonistic tumor necrosis factor (TNF) receptor binding agents

#692
20200079865
2020-03-12

Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR) and uses thereof

#693
20200079861
2020-03-12

Antibodies and methods of use thereof

#694
20200071412
2020-03-05

ANTIBODIES TO CD40 WITH ENHANCED AGONIST ACTIVITY

#695
20200071403
2020-03-05

Anti-LAG-3 antibodies and uses thereof

#696
20200071398
2020-03-05

Anti-LILRB3 antibodies and methods of use thereof

#697
20200062854
2020-02-27

Bispecific binding molecules that are capable of binding CD137 and tumor antigens, and uses thereof

#698
20200062848
2020-02-27

HUMAN MONOCLONAL ANTIBODIES TO PROGRAMMED DEATH LIGAND 1 (PD-L1)

#699
20200055931
2020-02-20

Anti-transferrin receptor antibodies with tailored affinity

#700
20200048681
2020-02-13

Antigen binding molecules and methods of use thereof

#701
20200048363
2020-02-13

Anti-OX40 antibodies and their uses

#702
20200048358
2020-02-13

BISPECIFIC ANTIBODY AGAINST OX40 AND CTLA-4

#703
20200048324
2020-02-13

Tissue-specific Wnt signal enhancing molecules and uses thereof

#704
20200046833
2020-02-13

AGONIST ANTIBODIES THAT BIND HUMAN CD137 AND USES THEREOF

#705
20200040098
2020-02-06

Anti-PD-1 antibodies and their uses

#706
20200040090
2020-02-06

Anti-CD40 antibodies

#707
20200031930
2020-01-30

Drug delivery compositions and uses thereof

#708
20200030425
2020-01-30

Anti-ICOS agonist antibodies and uses thereof

#709
20200025773
2020-01-23

Protein binding domains stabilizing functional conformational states of GPCRS and uses thereof

#710
20200024355
2020-01-23

USE OF ANTI-PD-1 ANTIBODY IN COMBINATION WITH ANTI-CD27 ANTIBODY IN CANCER TREATMENT

#711
20200024353
2020-01-23

PROTEINS BINDING PSMA, NKG2D AND CD16

#712
20200024339
2020-01-23

COMPOSITIONS AND METHODS FOR MODULATING CELL SIGNALING

#713
20200017596
2020-01-16

MONOCLONAL ANTIBODIES ACTIVATING CD40 AND USES THEREOF

#714
20200017595
2020-01-16

Binding molecules that bind CD137 and PD-L1

#715
20200017594
2020-01-16

IMMUNOMODULATORY ANTIBODIES

#716
20200017590
2020-01-16

Anti-TrkB agonist antibodies binding to D5 domain of TrkB and methods of promoting neuronal survival in motor neuron injury, stroke or glaucoma

#717
20200017589
2020-01-16

Anti-vista antibodies and fragments

#718
20200017587
2020-01-16

B7-DC BINDING ANTIBODY

#719
20200010558
2020-01-09

Anti-CD40 antibody

#720
20200010557
2020-01-09

Dysfunctional antigen-specific CD8T cells in the tumor microenvironment

#721
20190389961
2019-12-26

Compositions and methods for treating cancer

#722
20190383829
2019-12-19

PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF

#723
20190383828
2019-12-19

Protein binding domains stabilizing functional conformational states of GPCRs and uses thereof

#724
20190383826
2019-12-19

PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF

#725
20190383825
2019-12-19

PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF

#726
20190382503
2019-12-19

Oncofetal antigen binding proteins and related compositions and methods

#727
20190382492
2019-12-19

Drug delivery compositions and uses thereof

#728
20190382465
2019-12-19

Fusion Polypeptides Capable Of Activating Receptors

#729
20190375846
2019-12-12

BINDING AGENTS

#730
20190375843
2019-12-12

COMPOSITIONS AND METHODS FOR MODULATING IMMUNE RESPONSES

#731
20190367627
2019-12-05

Anti-OX40 antibodies and anti-GITR antibodies

#732
20190367626
2019-12-05

TRAILshort antibody and methods of use

#733
20190367613
2019-12-05

Methods of treating cancer in a subject having elevated ICOS and/or T-bet levels of CD+4 cells by administering an ICOS agonist

#734
20190361033
2019-11-28

DISTINGUISHING ANTAGONISTIC AND AGONISTIC ANTI B7-H1 ANTIBODIES

#735
20190359937
2019-11-28

CHIMERIC RECEPTORS, BIOSENSOR HOST CELLS AND METHODS/USES THEREOF

#736
20190359728
2019-11-28

ANTIBODY SUBSTITUTING FOR FUNCTION OF BLOOD COAGULATION FACTOR VIII

#737
20190359707
2019-11-28

Anti-SIRPA antibodies and methods of use thereof

#738
20190359696
2019-11-28

Methods of treating an osteolytic tumor and spinal cord injury by administering connexin (Cx) 43 hemichannel-binding antibodies

#739
20190352420
2019-11-21

Antagonizing CD73 antibody

#740
20190352414
2019-11-21

Anti-CD137 antibodies and uses thereof

#741
20190352411
2019-11-21

Anti-CD137 antibodies and uses thereof

#742
20190352410
2019-11-21

Nucleic acids encoding anti-OX40 antibodies

#743
20190352400
2019-11-21

Antibodies directed against ICOS and uses thereof

#744
20190352374
2019-11-21

NOVEL IGFR_LIKE 2 RECEPTOR AND USES THEREOF

#745
20190338041
2019-11-07

MULTIMERIC CD40 BINDING MOLECULES AND USES THEREOF

#746
20190338040
2019-11-07

MULTIMERIC CD137/4-1BB BINDING MOLECULES AND USES THEREOF

#747
20190338026
2019-11-07

Anti-leukocyte-associated immunoglobulin-like receptor 1 (LAIR1) monoclonal antibodies and method of use thereof to treat cancer

#748
20190330374
2019-10-31

MULTIMERIC OX40 BINDING MOLECULES AND USES THEREOF

#749
20190330366
2019-10-31

MULTISPECIFIC POLYPEPTIDE CONSTRUCTS HAVING CONSTRAINED CD3 BINDING AND RELATED METHODS AND USES

#750
20190330358
2019-10-31

IFN-gamma-inducible regulatory T cell convertible anti-cancer (IRTCA) antibody and uses thereof

#751
20190330355
2019-10-31

Anti-FGFR3 antibodies and methods using same

#752
20190330353
2019-10-31

IGF-1R antibody and its use as addressing vehicle for the treatment of cancer

#753
20190330349
2019-10-31

Anti-human VISTA antibodies and use thereof

#754
20190330335
2019-10-31

ANTI-TREM2 ANTIBODIES AND METHODS OF USE THEREOF

#755
20190330303
2019-10-31

Methods for cancer therapy using isolated NTB-A ectodomain polypeptides

#756
20190322743
2019-10-24

Agonistic antibodies that bind CD40

#757
20190315884
2019-10-17

MULTI-SPECIFIC ANTIGEN-BINDING MOLECULE HAVING ALTERNATIVE FUNCTION TO FUNCTION OF BLOOD COAGULATION FACTOR VIII

#758
20190315877
2019-10-17

Anti-DR5 antibodies and methods of use thereof

#759
20190315873
2019-10-17

Anti-MET antibodies and uses thereof

#760
20190315872
2019-10-17

Methods of treatment using anti-c-met antibodies

#761
20190315867
2019-10-17

Anti-TIGIT antibodies

#762
20190315866
2019-10-17

Antibodies directed against ICOS and uses thereof

#763
20190315858
2019-10-17

Anti-TREM2 antibodies and methods of use thereof

#764
20190309083
2019-10-10

Multivalent and multispecific DR5-binding fusion proteins and methods of treating neoplasms

#765
20190309082
2019-10-10

Anti-GITR antibodies and methods of use thereof

#766
20190309079
2019-10-10

Methods of treatment using a leptin receptor agonist antibody

#767
20190298816
2019-10-03

Anti-ICOS agonist antibodies and uses thereof

#768
20190284292
2019-09-19

4-1BB binding proteins and uses thereof

#769
20190284291
2019-09-19

Anti-OX40 antibodies

#770
20190284284
2019-09-19

Method of treating cancer in a patient by administering an antibody which binds colony stimulating factor-1 receptor (CSF-1R)

#771
20190284266
2019-09-19

Antibodies specific for hyperphosphorylated tau and methods of use thereof

#772
20190284265
2019-09-19

Antibodies specific for hyperphosphorylated tau and methods of use thereof

#773
20190276559
2019-09-12

Anti-TIE2 antibodies and uses thereof

#774
20190276551
2019-09-12

Antigen-binding polypeptides directed against CD38

#775
20190276549
2019-09-12

POLYPEPTIDE VARIANTS AND USES THEREOF

#776
20190276531
2019-09-12

Anti-TIM-3 antibodies and compositions

#777
20190275150
2019-09-12

Anti-SIRP-alpha antibodies and methods of use thereof

#778
20190270818
2019-09-05

PD-1 agonist antibodies and uses thereof

#779
20190270808
2019-09-05

Methods of treating an IGFBP-3R expressing cancer using anti-IGFBP-3R antibodies

#780
20190269776
2019-09-05

Agonist antibodies that bind human CD137 and uses thereof

#781
20190263918
2019-08-29

Sequence of antibody heavy chain constant region for enhancing agonistic antibody activity

#782
20190263916
2019-08-29

Multivalent and multispecific OX40-binding fusion proteins

#783
20190263908
2019-08-29

Immunoglobulins binding human Vγ9Vδ2 T cell receptors

#784
20190256605
2019-08-22

Dual receptor antagonistic antigen-binding proteins and uses thereof

#785
20190256599
2019-08-22

Anti-ICOS and anti-PD-1 antibody combination therapy

#786
20190256594
2019-08-22

Optimization of antibodies that bind lymphocyte activation gene-3 (LAG-3), and uses thereof

#787
20190248911
2019-08-15

Nucleic acids encoding an anti-CD40 antibody

#788
20190248906
2019-08-15

Antigen binding proteins that bind to a complex comprising β-Klotho and an FGF receptor

#789
20190241676
2019-08-08

Anti-MERTK agonistic antibodies and uses thereof

#790
20190233536
2019-08-01

Adenovirus armed with bispecific T cell engager

#791
20190233535
2019-08-01

IFN-γ-inducible regulatory T cell convertible anti-cancer (IRTCA) antibody and uses thereof

#792
20190233527
2019-08-01

Methods and compositions for treating inflammatory or autoimmune diseases or conditions using calcitonin receptor activators

#793
20190233516
2019-08-01

Non-cytotoxic modified cells and use thereof

#794
20190231865
2019-08-01

Agents that engage antigen-presenting cells through dendritic cell asialoglycoprotein receptor (DC-ASGPR)

#795
20190225687
2019-07-25

Anti-LAG-3 antibodies and uses thereof

#796
20190224315
2019-07-25

Agonist antibodies that bind human CD137 and uses thereof

#797
20190224298
2019-07-25

Platforms and methods for optimizing host antigen presentation and host antitumor and antipathogen immunity

#798
20190218296
2019-07-18

Anti-PD-L1 antibodies and methods of use

#799
20190211113
2019-07-11

BISPECIFIC ANTIBODIES WITH TETRAVALENCY FOR A COSTIMULATORY TNF RECEPTOR

#800
20190202932
2019-07-04

ANTI- EGFR CONFORMATIONAL SINGLE DOMAIN ANTIBODIES AND USES THEREOF

#801
20190202928
2019-07-04

Humanized Anti-CD134 (OX40) Antibodies And Uses Thereof

#802
20190202926
2019-07-04

ANTI-DEATH RECEPTOR ANTIBODIES AND METHODS OF USE THEREOF

#803
20190202912
2019-07-04

Antibodies for Siglec-15 and methods of use thereof

#804
20190201513
2019-07-04

Anti-CD277 antibodies

#805
20190194690
2019-06-27

Oncolytic group B adenovirus expressing a stroma-targeted bispecific t-cell engager

#806
20190194329
2019-06-27

Anti-4-1BB antibodies and their uses

#807
20190194322
2019-06-27

Identification of VSIG3/VISTA as a novel immune checkpoint and use thereof for immunotherapy

#808
20190194321
2019-06-27

Methods of treating autoimmune disease or chronic inflammation with antibodies that bind and block triggering receptor expressed on myeloid cells-1 (TREM-1)

#809
20190194304
2019-06-27

FACTOR H POTENTIATING ANTIBODIES AND USES THEREOF

#810
20190185563
2019-06-20

Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS

#811
20190185562
2019-06-20

Bispecific antigen binding molecules that bind leptin receptor and/or GP130, and methods of use thereof

#812
20190185549
2019-06-20

Broadly cross-reactive HIV-1-specific antibodies for prevention and treatment of HIV

#813
20190177746
2019-06-13

Retroviral and lentiviral vectors

#814
20190177432
2019-06-13

Host cell comprising nucleic acids encoding bispecific antibodies binding to beta-klotho and fibroblast growth factor receptor 1 and antibody production

#815
20190177422
2019-06-13

Anti-OX40 binding proteins

#816
20190177418
2019-06-13

TrkB agonist antibodies and methods for treating an ocular degenerative disorder characterized by degeneration of retinal ganglion cells (RGCs)

#817
20190177410
2019-06-13

Fusion protein comprising apelin and an anti-APLNR antibody

#818
20190175705
2019-06-13

Anti-ICOS agonist antibodies and uses thereof

#819
20190169308
2019-06-06

NOVEL BISPECIFIC POLYPEPTIDES AGAINST CD137

#820
20190169306
2019-06-06

CANCER AND B-CELL RELATED DISEASE THERAPY

#821
20190169304
2019-06-06

COMBINATION THERAPY COMPRISING OX40 BINDING AGONISTS AND TIGIT INHIBITORS

#822
20190169302
2019-06-06

Variant antibodies that bind OX40

#823
20190167704
2019-06-06

Therapeutic combinations comprising anti-FOLR1 immunoconjugates

#824
20190161555
2019-05-30

Bispecific Antibodies Directed Against OX40 and a Tumor-Associated Antigen

#825
20190161554
2019-05-30

Antibody therapeutics that bind CD137

#826
20190161551
2019-05-30

Anti-TrkB monoclonal antibodies and methods of use

#827
20190161546
2019-05-30

SP35 Antibodies And Uses Thereof

#828
20190153112
2019-05-23

Anti-LAG-3 antibodies

#829
20190153098
2019-05-23

Drug delivery compositions and uses thereof

#830
20190153086
2019-05-23

Heterodimeric immunoglobulins

#831
20190151469
2019-05-23

RNA containing composition for treatment of tumor diseases

#832
20190151351
2019-05-23

REGULATORS OF ANAPLASTIC LYMPHOMA KINASE AND USES THEREOF

#833
20190144554
2019-05-16

ANTI-DR5 ANTIBODIES AND METHODS OF USE THEREOF

#834
20190144514
2019-05-16

C3D cellular and acellular vaccines for the prevention and treatment of cancer

#835
20190135933
2019-05-09

Combining CD27 agonists and immune checkpoint inhibition for immune stimulation

#836
20190135929
2019-05-09

AGONISTIC ANTI-TUMOR NECROSIS FACTOR RECEPTOR 2 ANTIBODIES

#837
20190127477
2019-05-02

Anti-SIRPa antibodies and their therapeutic applications

#838
20190125867
2019-05-02

THERAPEUTIC AGENT FOR SOLID CANCER

#839
20190119634
2019-04-25

Methods for selective expansion of γδ T-cell populations and compositions thereof

#840
20190119394
2019-04-25

Compositions and methods for treating pancreatitis and pain with death receptor agonists

#841
20190119376
2019-04-25

ANTI-TIGIT ANTIBODIES AND METHODS OF USE

#842
20190112392
2019-04-18

T cell recruiting polypeptides based on TCR alpha/beta reactivity

#843
20190112390
2019-04-18

ANTIBODY SUBSTITUTING FOR FUNCTION OF BLOOD COAGULATION FACTOR VIII

#844
20190112371
2019-04-18

Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS

#845
20190111148
2019-04-18

IL-21 agonist antibodies and methods of treatment using same

#846
20190106496
2019-04-11

Methods Of Identifying Anti-Inflammatory Compounds

#847
20190106493
2019-04-11

Immunological reagents

#848
20190106490
2019-04-11

Beta klotho-binding proteins and methods of use thereof

#849
20190100596
2019-04-04

Anti-OX40 antibodies and methods of using the same

#850
20190100583
2019-04-04

IL-17A/F HETEROLOGOUS POLYPEPTIDES AND THERAPEUTIC USES THEREOF

#851
20190099450
2019-04-04

PD-L1 expressing hematopoietic stem cells and uses

#852
20190085087
2019-03-21

STROMAL GENE SIGNATURES FOR DIAGNOSIS AND USE IN IMMUNOTHERAPY

#853
20190085080
2019-03-21

B7-H4 antibodies and methods of use thereof

#854
20190083626
2019-03-21

Method of treating cancer with a biomaterial and a toll-like receptor agonist

#855
20190077863
2019-03-14

Methods of treating ocular conditions by administering humanized monoclonal antibodies that target VE-PTP (HPTP-beta)

#856
20190077862
2019-03-14

Humanized monoclonal antibodies that target protein tyrosine phosphatase-beta (HPTP-β/VE-PTP)

#857
20190077848
2019-03-14

Antiviral immunotherapy by membrane receptor ligation

#858
20190076515
2019-03-14

Anti-ICOS agonist antibodies and uses thereof

#859
20190071515
2019-03-07

Compositions and methods for regulating erythropoiesis

#860
20190071513
2019-03-07

Methods of treatment of CD123 overexpressing disorders

#861
20190071511
2019-03-07

IMMUNOGLOBULIN VARIANTS AND USES THEREOF

#862
20190071510
2019-03-07

Anti-human 4-1BB antibodies and uses thereof

#863
20190071509
2019-03-07

Nucleic acid molecules encoding anti-CD40 antibodies

#864
20190071503
2019-03-07

Humanized Anti-HLA-DR Antibodies

#865
20190071497
2019-03-07

Methods of treating cancer using an IL-21 agonist

#866
20190071483
2019-03-07

Antibody peptide conjugates that have agonist activity at both the glucagon and glucagon-like peptide 1 receptors

#867
20190062453
2019-02-28

Antibodies specific for DR5 and methods of use

#868
20190062446
2019-02-28

Anti-GITR antibodies and methods of use thereof

#869
20190062445
2019-02-28

FULLY HUMAN ANTIBODIES AGAINST HUMAN 4-1BB

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20190062444
2019-02-28

COMBINATION THERAPY COMPRISING ANTI-ANGIOGENESIS AGENTS AND OX40 BINDING AGONISTS

#871
20190062443
2019-02-28

Highly potent antibodies binding to death receptor 4

#872
20190062431
2019-02-28

Immunological reagents

#873
20190062427
2019-02-28

Anti-Siglec-9 antibodies and methods of use thereof

#874
20190062420
2019-02-28

Fc γ RIII binding fibronectin type III domains, their conjugates and multispecific molecules comprising them

#875
20190060454
2019-02-28

Agonist antibodies that bind human CD137 and uses thereof

#876
20190055315
2019-02-21

Multispecific NK engager protein

#877
20190055314
2019-02-21

Anti-CD137 molecules and use thereof

#878
20190054189
2019-02-21

RNA containing composition for treatment of tumor diseases

#879
20190049463
2019-02-14

Protein binding domains stabilizing functional conformational states of GPCRs and uses thereof

#880
20190048093
2019-02-14

Multispecific NK engager protein

#881
20190048078
2019-02-14

Engineered antibody Fc variants for enhanced serum half life

#882
20190048074
2019-02-14

Method for treating pathological angiogenesis by administering an antibody that inhibits APLNR

#883
20190041400
2019-02-07

PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF

#884
20190040153
2019-02-07

FGF21 mimetic antibodies and uses thereof

#885
20190040142
2019-02-07

METHODS OF SCREENING FOR MULTISPECIFIC ANTIBODIES

#886
20190040130
2019-02-07

Anti-TREM2 antibodies and methods of use thereof

#887
20190031777
2019-01-31

Compositions and methods for detecting, treating and preventing diseases and disorders

#888
20190031765
2019-01-31

COMBINATION OF AN OX40 AGONIST AND A 4-1BB AGONIST MONOCLONAL ANTIBODY FOR TREATING CANCER

#889
20190030162
2019-01-31

Combination Therapies Employing GITR Binding Molecules

#890
20190025327
2019-01-24

Therapeutic and diagnostic methods for autism spectrum disorders and other conditions

#891
20190023799
2019-01-24

Methods for inducing or enhancing an immune response by administering agonistic glucocorticoid-induced TNFR-family-related receptor (GITR) antibodies

#892
20190023773
2019-01-24

ANTIBODIES THAT BIND HUMAN PROTEIN TYROSINE PHOSPHATASE beta (HPTPbeta) AND USES THEREOF

#893
20190016816
2019-01-17

Oncofetal antigen binding proteins and related compositions and methods

#894
20190016800
2019-01-17

Antibodies binding LAG-3 and uses thereof

#895
20190015508
2019-01-17

Agonist antibodies that bind human CD137 and uses thereof

#896
20190010501
2019-01-10

Targeting WSB1 and pVHL to treat cancer

#897
20190010242
2019-01-10

Multispecific polypeptide constructs having constrained CD3 binding and methods of using the same

#898
20190010241
2019-01-10

Binding agents

#899
20190010239
2019-01-10

Anti-GITR antibodies and methods of use thereof

#900
20190010230
2019-01-10

ANTI-TREM2 ANTIBODIES AND METHODS OF USE THEREOF