97307 ⎘
Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
MODIFIED ANTIGEN-BINDING FAB FRAGMENTS AND ANTIGEN-BINDING MOLECULES COMPRISING THE SAME
#6302NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF
#6303Fc mutants with improved functional activity
#6304Bispecific Polypeptides to GITR and CTLA-4
#6305Anti-GITR antibodies and methods of use thereof
#6306ANTI-RANKL ANTIBODIES AND METHODS OF USE
#6307Methods of treatment using a leptin receptor agonist antibody
#6308Treatment of tumors with an anti-CSF-1R antibody in combination with an anti-PD-L1 antibody after failure of anti-PD-L1/PD1 treatment
#6309Compositions and methods comprising anti-NRP2 antibodies
#6310PD-1 antibody, antigen-binding fragment thereof, and medical application thereof
#6311Bispecific trivalent antibodies binding to Claudin6 or Claudin18.2 and CD3 for treatment of Claudin expressing cancer diseases
#6312Anti-TREM2 antibodies and related methods
#6313Anti-human Igβ antibody
#6314Methods and agents for the diagnosis and treatment of hepatocellular carcinoma
#6315INTESTINAL ANTIGENS FOR PHARMACODELIVERY APPLICATIONS
#6316HIGHLY GALACTOSYLATED ANTI-TNF-ALPHA ANTIBODIES AND USES THEREOF
#6317HIGHLY GALACTOSYLATED ANTI-TNF-ALPHA ANTIBODIES AND USES THEREOF
#6318Immunoglobulin single variable domains directed against macrophage migration inhibitory factor
#6319Anti-BAFF antibodies
#6320Compositions
#6321Immune complex
#6322Anti-TMPRSS2 antibodies and antigen-binding fragments
#6323Anti-PSMA antibodies, uses thereof and conjugates thereof
#6324Conjugates of IL13Rα2 binding agents and use thereof in cancer treatment
#6325ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOF
#6326Anti-CD25 antibody agents
#6327Anti-canine platelet derived growth factor receptor alpha antibody
#6328Therapeutic CD47 antibodies
#6329Anti-TREM-1 antibodies and uses thereof
#6330COMPOSITION CONTAINING ANTI-ROBO4 ANTIBODY AND OTHER AGENTS
#6331Anti-family with sequence similarity 19, member A5 antibodies and method of use thereof
#6332PREVENTION AND TREATMENT OF SYNUCLEINOPATHIC AND AMYLOIDOGENIC DISEASE
#6333Anti-equol antibody composition and use therefor
#6334Antibody-coupled cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide Y receptors
#6335Anti-ICOS agonist antibodies and uses thereof
#6336Programmed death 1 ligand 1 (PD-L1) binding proteins and methods of use thereof
#6337MYCOBACTERIUM TUBERCULOSIS PROTEINS IN DIAGNOSTIC ASSAYS AND DEVICES FOR TUBERCULOSIS DETECTION AND DIAGNOSIS
#6338Internalizing moieties
#6339Binding molecules specific for CD73 and uses thereof
#6340ANTIBODIES AGAINST THE ECTODOMAIN OF ERBB3 AND USES THEREOF
#6341Methods for producing fabs and IgG bispecific antibodies
#6342Bispecific CXCR4-CD4 polypeptides with potent anti-HIV activity
#6343NOVEL BINDING PROTEINS COMPRISING A UBIQUITIN MUTEIN AND ANTIBODIES OR ANTIBODY FRAGMENTS
#6344KLRG1 antagonist signaling therapy
#6345GENETICALLY MODIFIED NON-HUMAN ANIMALS FOR GENERATING THERAPEUTIC ANTIBODIES AGAINST PEPTIDE-MHC COMPLEXES, METHODS OF MAKING AND USES THEREOF
#6346Anti-PD-1 antibodies
#6347Anti-CD47 antibodies
#6348Amyloid beta oligomer specific binding molecule
#6349Humanized anti-tau antibodies and compositions for and methods of making and using in treatment, diagnosis and monitoring of tauopathies
#6350Composition and method for the diagnosis and treatment of iron-related disorders
#6351Hybridoma cell line of secreting clarithromycin monoclonal antibodies and preparation method thereof
#6352Human anti-SOD1 antibodies
#6353Heterodimeric immunoglobulin constructs and preparation methods thereof
#6354Antibodies that bind CD39 and uses thereof
#63554-1BB binding proteins and uses thereof
#6356Anti-OX40 antibodies
#6357Anti-RANKL antibodies and uses thereof
#6358Anti-CD25 antibody agents
#6359BISPECIFIC ANTIBODY BINDING TO HUMAN CD19 AND CD3
#6360Humanized or chimeric CD3 antibodies
#6361Anti-LAG3 antibodies and uses thereof
#6362T cell receptors and immune therapy using the same
#6363Anti-KRAS binding proteins
#6364ERFE SPECIFIC ANTIBODIES COMPOSITIONS AND METHODS OF USE
#6365Interleukin-31 monoclonal antibodies for veterinary use
#6366Tau-binding antibodies
#6367Antibodies specific for hyperphosphorylated tau and methods of use thereof
#6368Antibodies specific for hyperphosphorylated tau and methods of use thereof
#6369T cell receptor-like antibodies specific for Foxp3-derived peptides
#6370Anti-TIE2 antibodies and uses thereof
#6371Thrombin-Binding Antibody Molecules And Uses Thereof
#6372TAG-72-binding chimeric antigen receptors
#6373Antigen-binding polypeptides directed against CD38
#6374POLYPEPTIDE VARIANTS AND USES THEREOF
#6375Anti-NGF antibodies and methods thereof
#6376Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (GIPR) in combination with GLP-1 agonists
#6377Anti-PD1 and anti-CTLA4 antibodies
#6378HUMAN ANTIBODIES THAT BIND LYMPHOCYTE ACTIVATION GENE-3 (LAG-3), AND USES THEREOF
#6379Human antibodies that bind lymphocyte activation gene-3 (LAG-3), and uses thereof
#6380ANTIGEN BINDING PROTEINS
#6381Anti-Tim-3 antibodies for combination with anti-PD-1 antibodies
#6382Anti-Tim-3 antibodies and use thereof
#6383Anti-TIM-3 antibodies and compositions
#6384Composition and methods of treating B cell disorders
#6385Antibodies to alpha-synuclein and uses thereof
#6386Human Zika virus antibodies and methods of use therefor
#6387Immunogenetic restriction on elicitation of antibodies
#6388Anti-SIRP-alpha antibodies and methods of use thereof
#6389Antibodies binding AXL
#6390Antibodies to CD70
#6391Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
#6392Anti-PD-1 antibodies
#6393Antibodies specific to FCRN
#6394Humanized anti-BASIGIN antibodies and the use thereof
#6395Methods of determining whether anti-PACAP antibodies inhibit PACAP-associated photophobia or light aversion
#6396IL-6 antibodies and fusion constructs and conjugates thereof
#6397ANTAGONISTS OF IL-6 TO PREVENT OR TREAT CACHEXIA, WEAKNESS, FATIGUE, AND/OR FEVER
#6398IL-17 ANTAGONISTIC ANTIBODIES
#6399RGMa binding protein and use thereof
#6400Anti-ApoE antibodies
#6401Anti-human MUC1 antibody fab fragment
#6402Cytotoxic benzodiazepine derivatives
#6403Preparation of bioconjugates and antibodies for the immunodetection of anatoxin-a
#6404Anti-TrkA antibody
#6405Antibodies directed to HER-3 and uses thereof
#6406Cytotoxic benzodiazepine derivatives
#6407CD20 antibodies
#6408Bispecific antibody against BCMA and CD3 and an immunological drug for combined use in treating multiple myeloma
#6409Sequence of antibody heavy chain constant region for enhancing agonistic antibody activity
#6410Cysteine engineered fibronectin type III domain binding molecules
#6411Bispecific and monospecific antibodies using novel anti-PD-1 sequences
#6412Antibody constructs for DLL3 and CD3
#6413CD3 binding antibodies
#6414Humanized M-CSF specific monoclonal antibodies, kits, and uses thereof
#6415Anti-tau nanobodies
#6416Methods of treating atypical hemolytic uremic syndrome and paroxysmal nocturnal hemoglobinuria with anti-C5 antibodies
#6417Recombinant antibody and uses thereof
#6418Fibronectin based scaffold proteins having improved stability
#6419Relaxin immunoglobulin fusion proteins and methods of use
#6420Immunoglobulins and uses thereof
#6421PROTEIN CAPABLE OF BINDING SPECIFICALLY TO IMMUNOGLOBULIN, AND IMMUNOGLOBULIN-BINDING AFFINITY LIGAND
#6422Glucocorticoid receptor agonist and immunoconjugates thereof
#6423Antibodies specific for LOX1 and use in treatment of cardiovascular disorders
#6424Genetically modified non-human animals and methods for producing heavy chain-only antibodies
#6425Nucleic acids encoding high affinity antibodies to human IL-6 receptor
#6426Dual receptor antagonistic antigen-binding proteins and uses thereof
#6427Binding molecules binding PD-L1 and LAG-3
#6428Anti-PD-1 antibodies and methods of use thereof
#6429Antibodies directed against programmed death-1 (PD-1)
#6430Anti-ICOS and anti-PD-1 antibody combination therapy
#6431Anti-CD73 antibodies and uses thereof
#6432Optimization of antibodies that bind lymphocyte activation gene-3 (LAG-3), and uses thereof
#6433CD33 BINDING AGENTS
#6434Antibody specifically binding to IL-17A, encoding nucleic acid, and method of using the antibody
#6435Antibody specifically binding to an isolated peptide derived from vimentin or a fragment binding to the peptide
#6436Anti-respiratory syncytial virus antibodies, and methods of their generation and use
#6437Middle east respiratory syndrome coronavirus immunogens, antibodies, and their use
#6438T cell receptors and immune therapy using the same against prame positive cancers
#6439Method of treating inflammatory bowel disease
#6440Use of myostatin inhibitors and combination therapies
#6441Fusion proteins comprising enzyme replacement therapy enzymes
#6442Chemically-locked bispecific antibodies
#6443Bi-specific antigen-binding polypeptides
#6444Combination of ABCG2 inhibitors with sacituzumab govitecan (IMMU-132) overcomes resistance to SN-38 in Trop-2 expressing cancers
#6445Antibodies binding to HLA-A2/WT1
#6446Nucleic acids encoding an anti-CD40 antibody
#6447Methods of inhibiting naive T-cell proliferation using anti-CD27 antibodies
#6448Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (CSF1R)
#6449Anti-human BDCA-2 antibody
#6450Anti-CLL-1 antibodies and immunoconjugates
#6451Methods of treating cardiovascular disease with an anti-ASGR antibody or binding fragments thereof
#6452Antibodies to MICA and MICB proteins
#6453Antibody to programmed cell death 1 (PD-1) and use thereof
#6454Mixtures of antibodies
#6455Bispecific Asymmetric Heterodimers Comprising Anti-CD3 Constructs
#6456TREATMENT WITH ANTI-KIR3DL2 AGENTS
#6457Anti-FcRn antibodies
#6458EXTRACELLULAR TARGETED DRUG CONJUGATES
#6459Method for treating lupus by administering an anti-IL-12 antibody
#6460Methods of treating cancer with human monoclonal antibodies against interleukin 8 (IL-8)
#6461Heavy chain only antibodies to ANG-2
#6462Neutralizing anti-influenza A virus antibodies and uses thereof
#6463Fc FUSION PROTEINS COMPRISING NOVEL LINKERS OR ARRANGEMENTS
#6464Anti-PD-L1-anti-TIM-3 bispecific antibodies
#6465Compound targeting IL-23A and B-cell activating factor (BAFF) and uses thereof
#6466Antibodies that bind Notum Pectinacetylesterase
#6467Anti-MERTK agonistic antibodies and uses thereof
#6468Chimeric antigen receptors targeting B-cell maturation antigen
#6469Antibody-drug conjugates comprising anti-prolactin receptor (PRLR) antibodies and methods of use thereof to kill PRLR-expressing cells
#6470Anti-B7-H4 antibodies and immunoconjugates
#6471Anti-CTLA4 antibodies and methods of making and using the same
#6472BISPECIFIC ANTIBODY-LIKE BINDING PROTEINS SPECIFICALLY BINDING TO CD3 AND CD123
#6473Antibodies with low immunogenicity and uses thereof
#6474MATRIX METALLOPROTEASE-CLEAVABLE AND SERINE PROTEASE-CLEAVABLE SUBSTRATES AND METHODS OF USE THEREOF
#6475Anti-ApoC3 antibodies and methods of use thereof
#6476Compositions And Methods For Treating Angiogenesis-Related Disorders
#6477ANTIGEN-COUPLED HYBRIDIZATION REAGENTS
#6478Low-viscosity antigen binding proteins and methods of making them
#6479Anti-PCSK9 antibodies
#6480Anti-PCSK9 antibody and use thereof
#6481HER2/neu-specific antibodies and methods of using same
#6482Humanized antibody against O-acetylated GD2 ganglioside (OAcGD2)
#6483IFN-γ-inducible regulatory T cell convertible anti-cancer (IRTCA) antibody and uses thereof
#6484Site-specific antibody-drug conjugation through glycoengineering
#6485Antibodies specific for CD70 and their uses
#6486Chimeric antigen receptors targeting CD70
#6487ANTI-HUMAN CD69 ANTIBODY, AND USE THEREOF FOR MEDICAL PURPOSES
#6488ANTI HLA-G SPECIFIC ANTIBODIES
#6489Single-domain antibodies and variants thereof against CTLA-4
#6490Anti-PD-1/LAG3 bispecific antibodies
#6491Fabs-in-tandem immunoglobulin and uses thereof
#6492ANTI-FOLATE RECEPTOR ANTIBODIES, COMPOSITIONS COMPRISING ANTI-FOLATE RECEPTOR ANTIBODIES AND METHODS OF MAKING AND USING ANTI-FOLATE RECEPTOR ANTIBODIES
#6493IL-6 binding molecules
#6494Methods of detecting human IL-21
#6495Human Anti-Tau Antibodies
#6496Neutralizing anti-influenza B antibodies and uses thereof
#6497Anti-PACAP antibodies and uses thereof
#6498KIDNEY DISEASE TARGETS AND USES THEREOF
#6499FORMULATION FOR ANTI-ALPHA4BETA7 ANTIBODY AND METHODS OF TREATMENT
#6500Vaccine composition comprising cyclic peptides, antibodies to the cyclic peptides or an anticancer composition comprising the same
#6501Agents that engage antigen-presenting cells through dendritic cell asialoglycoprotein receptor (DC-ASGPR)
#6502Diagnostic assays and kits for detection of folate receptor 1
#6503Influenza mucosal vaccine composition and preparation and application thereof
#6504Antibodies with reduced binding to process impurities
#6505Antibodies against factor XI and uses thereof
#6506CD73 blocking agents
#6507Methods for the treatment of thyroid eye disease
#6508Anti-PD-L1 antibodies and variants
#6509Anti-CTLA4 antibodies
#6510Anti-LAG-3 antibodies and uses thereof
#6511Anti-IGF antibodies
#6512Tenascin Epitope and Antibodies Thereto
#6513Fusion proteins for opthalmology with increased eye retention
#6514Methods, compositions and kits for treating a subject using a recombinant neutralizing binding protein
#6515TRANSGENIC NON-HUMAN ANIMALS PRODUCING MODIFIED HEAVY CHAIN-ONLY ANTIBODIES
#6516Antigen binding proteins that bind WISP1
#6517Human antibody specifically binding to acne bacteria using phage display technique, and use thereof
#6518Cellular vamp cleavage assay
#6519Bispecific antigen binding construct
#6520Drug containing carrier into cell for forming immune complex
#6521RESTORATION OF T CELL ACTIVITY VIA THE CD39/CD73 AXIS
#6522CD37-binding molecules and immunoconjugates thereof
#6523Methods of treating severe insulin resistance by interfering with glucagon receptor signaling
#6524Neutralizing antibodies to the αvβ8 integrin complex for immunotherapy
#6525Methods of cancer treatment and therapy using a combination of antibodies that bind glycosylated PD-L1
#6526Anti-PD-L1 antibodies and methods of use
#6527Anti-PD-1 antibodies
#6528Compositions for achieving therapeutically effective doses of anti-CD47 agents
#6529FcγRIIB-specific antibodies and methods of use thereof
#6530Compositions and methods for measuring NMU and for treatment using anti-NMU agents
#6531Methods for inhibiting myostatin activation by administering anti-pro/latent myostatin antibodies
#6532NOVEL ANTIBODY FORMAT
#6533PAC1 antibodies and uses thereof
#6534Anti-dengue virus antibodies, polypeptides containing variant Fc regions, and methods of use
#6535Immunoglobulin constant region Fc receptor binding agents
#6536Antibody-polymer-drug conjugates
#6537Methods for producing Fabs and bi-specific antibodies
#6538Method of inhibiting the enzymatic activity of vascular endothelial lipase with a monoclonal antibody
#6539BISPECIFIC ANTIBODIES WITH TETRAVALENCY FOR A COSTIMULATORY TNF RECEPTOR
#6540Amino acid sequences that modulate the interaction between cells of the immune system
#6541Human CD3 binding antibody
#6542USE OF PILRA BINDING AGENTS FOR TREATMENT OF A DISEASE
#6543Polypeptide targeting aptamers for characterization, capture, and clinical management of circulating tumor cells
#6544Anti-complement factor C1q antibodies and uses thereof
#6545Human immunodeficiency virus neutralizing antibodies
#6546Method for purifying antibody or antibody fragment containing κ-chain variable region
#6547ANTIBODY CONSTANT REGION VARIANT
#6548Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, Bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
#6549Transgenic non-human vertebrate for the expression of class-switched, fully human, antibodies
#6550Quantitative ligandomics for systematic identification of therapeutic ligands
#6551INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF ASPARTYL-TRNA SYNTHETASES
#6552Heterodimeric antibodies that bind CD3 and tumor antigens
#6553Low affinity blood brain barrier receptor antibodies and uses thereof
#6554Cys80 conjugated immunoglobulins
#6555ANTI- EGFR CONFORMATIONAL SINGLE DOMAIN ANTIBODIES AND USES THEREOF
#6556Humanized Anti-CD134 (OX40) Antibodies And Uses Thereof
#6557Anti-CD71 antibodies, activatable anti-CD71 antibodies, and methods of use thereof
#6558Humanized anti-tumor necrosis factor alpha receptor 2 (anti-TNFR2) antibodies and methods of use thereof to elicit an immune response against a tumor
#6559Anti human interleukin-1 receptor accessory protein (IL1 RAP) antibodies and uses thereof
#6560Anti-CSF1R antibody and anti PD-1 antibody combination therapy for cancer
#6561EGFR binding molecules
#6562Antibodies binding CTLA-4 and uses thereof
#6563Antibodies for Siglec-15 and methods of use thereof
#6564Methods for treating autoimmune diseases incorporating an anti-LAG3 antibody
#6565Antibodies against Frizzled receptor
#6566Antibodies for IL-17C
#6567Synthetic antibodies against VEGF and their uses
#6568Anti-VEGF-A antibodies and uses thereof
#6569ANTIBODY VARIANTS
#6570AGLYCOSYLATED ANTI-C3b ANTIBODIES AND USES THEREOF
#6571Targeted therapeutics based on engineered proteins for tyrosine kinases receptors, including IGF-IR
#6572Compositions relating to a mutant clostridium difficile toxin and methods thereof
#6573Anti-IL-23 antibodies
#6574Cysteine-optimized stradomers
#6575Antibody to Renalase
#6576Tissue plasminogen activator antibodies and methods of use
#6577MONOCLONAL ANTIBODIES AGAINST TISSUE FACTOR PATHWAY INHIBITOR (TFPI)
#6578Anti-factor IX Padua antibodies
#6579Antigen binding protein against HER3
#6580ANTIBODIES SELECTIVE FOR CELLS PRESENTING ERBB2 AT HIGH DENSITY
#6581ANTIBODIES FOR EPIDERMAL GROWTH FACTOR RECEPTOR 3 (HER3)
#6582Anti-5T4 antibodies and antibody-drug conjugates
#6583ANTI-SAS1B ANTIBODIES, ASSOCIATED METHODS OF USE, AND COMPOSITIONS AND METHODS FOR DETECTING AND TREATING CANCER
#6584Methods of treating immunotherapy-related toxicity using a GM-CSF antagonist
#6585Antibodies specific for epidermal growth factor receptor variant III and their uses
#6586Anti-TEM1 antibodies and uses thereof
#6587TREATMENT OF PD-L1-NEGATIVE MELANOMA USING AN ANTI-PD-1 ANTIBODY AND AN ANTI-CTLA-4 ANTIBODY
#6588Antibodies to LILRB2
#6589Treatment and sustained virologic remission of HIV infection by antibodies to CD4 in HAART stabilized patients
#6590Anti-Siglec-7 antibodies for the treatment of cancer
#6591Methods of treating autoimmune disease or chronic inflammation with antibodies that bind and block triggering receptor expressed on myeloid cells-1 (TREM-1)
#6592IL-6 antibodies
#6593Anti-TNF-alpha-antibodies and functional fragments thereof
#6594Macrophage stimulating protein receptor (or RON—recepteur d'Origine Nantais) antibodies and uses thereof
#6595Anti-VEGF-A and anti-ANG2 antibodies and uses thereof
#6596Single domain binding molecule
#6597Variant antibodies that bind AIP2
#6598Middle east respiratory syndrome coronavirus neutralizing antibodies and methods of use thereof
#6599C-TERMINALLY FUSED TNF FAMILY LIGAND TRIMER-CONTAINING ANTIGEN BINDING MOLECULES
#6600Use of FCRN antagonists for treatment of generalized myasthenia gravis