97307 ⎘
Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Compound targeting IL-23A and B-cell activating factor (BAFF) and uses thereof
#9002Factor XI antibodies and methods of use
#9003Immunoactivating antigen-binding molecule
#9004Multispecific GITR-binding fusion proteins and methods of use thereof
#9005Humanized anti-CD70 binding agents and uses thereof
#9006Prolactin receptor binding proteins and uses thereof
#9007Insulin-like growth factor 1 receptor-specific antibodies and uses thereof
#9008Antibodies that bind to MHC class I polypeptide-related sequence A
#9009T-cell redirecting bispecific antibodies for treatment of disease
#9010Antibody therapeutics that bind LAG3
#9011MULTIPLE-VARIABLE DOSE REGIMEN FOR TREATING TNFALPHA-RELATED DISORDERS
#9012ANTIGEN-BINDING MOLECULE PROMOTING DISAPPEARANCE OF ANTIGENS HAVING PLURALITY OF BIOLOGICAL ACTIVITIES
#9013Anti-Aβ globulomer 4D10 antibodies
#9014Antibodies specific to pyroglutamated Aβ
#9015METHODS FOR SYSTEMATIC CONTROL OF PROTEIN STABILITY
#9016Carrier-antibody compositions and methods of making and using the same
#9017Carrier-antibody compositions and methods of making and using the same
#9018SYSTEM AND METHOD FOR IMPROVED TRANSIENT PROTEIN EXPRESSION IN CHO CELLS
#9019Binding fusion proteins, binding fusion protein-drug conjugates, XTEN-drug conjugates and methods of making and using same
#9020Anti-fibulin-3 antibodies and uses thereof
#9021NUCLEIC ACIDS ENCODING HUMAN ANTIBODIES TO SIALYL-LEWIS A
#9022Nucleic acids encoding antibody polypeptides that antagonize CD40
#9023Multivalent and multispecific DR5-binding fusion proteins
#9024Antibodies against human CSF-1R and uses thereof
#9025ACTRIIA BINDING AGENTS AND USES THEREOF
#9026Human antigen binding proteins that bind β-Klotho, FGF receptors and complexes thereof
#9027Insulin-like growth factor 1 receptor-specific antibodies and uses thereof
#9028Insulin-like growth factor 1 receptor-specific antibodies and uses thereof
#9029Anti-erythropoietin antibodies
#9030Antibodies against platelet-derived growth factor (PDGF)
#9031Agents, uses and methods for the treatment of synucleinopathy
#9032Antibodies specific for hyperphosphorylated tau and methods of use thereof
#9033Anti-transthyretin antibodies
#9034Anti-glucosaminidase passive immunization for infections
#9035Compositions and methods for treating and preventing infections
#9036Antibody-drug conjugates and uses thereof
#9037ANTI-NOTCH3 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES
#9038AURISTATIN-ANTIBODY CONJUGATES AND USES THEREOF
#9039Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
#9040Antibodies comprising C-terminal light chain polypeptide extensions and conjugates and methods of use thereof
#9041Anti-TLR4 antibodies and uses thereof
#9042ANTIBODY DRUG CONJUGATES
#9043Treatment of cancer using humanized anti-EGFRvIII chimeric antigen receptor
#9044Therapeutic peptides
#9045Oncostatin M receptor antigen binding proteins
#9046HUMANIZED BETA-AMYLOID BINDING MOLECULES AND USES THEREOF
#9047Means and methods for producing stable antibodies
#9048Antibody-drug conjugates and immunotoxins
#9049Assay for methoxetamine
#9050METHODS AND MATERIALS FOR ASSESSING ENZYME-NUCLEIC ACID COMPLEXES
#9051Plasma kallikrein binding proteins and uses thereof in treating hereditary angioedema
#9052Anti-MCAM antibodies and associated methods of use
#9053COMPOSITIONS AND METHODS FOR THE DETECTION DIAGNOSIS AND THERAPY OF HEMATOLOGICAL MALIGNANCIES
#9054Activatable antibodies that bind interleukin-6 receptor and methods of use thereof
#9055Antibody against the CSF-1R
#9056Antibodies With Modified Affinity To FcRn That Promote Antigen Clearance
#9057ST2 antigen binding proteins
#9058Methods of treating ulcerative colitis
#9059TARGETING AGENT ANTIBODY CONJUGATES AND USES THEREOF
#9060Anti-CD33 antibodies and immunoconjugates
#9061Human IL-23 antigen binding proteins
#9062Polypeptides
#9063Anti-C5a binding moieties with high blocking activity
#9064Antibodies With Modified Affinity To FcRn That Promote Antigen Clearance
#9065Use of VHH antibodies for the preparation of peptide vectors for delivering a substance of interest and their applications
#9066scFV antibody library
#9067PROTEINS COMPRISING BINDING REGIONS, SHIGA TOXIN A SUBUNIT EFFECTOR REGIONS, AND CARBOXY-TERMINAL, ENDOPLASMIC RETICULUM LOCALIZATION SIGNAL MOTIFS
#9068Anti-DLL3 antibody drug conjugates for treating cancer
#9069Therapeutic biologic for treatment of hepatocellular carcinoma
#9070Anti-KRS monoclonal antibody and use thereof
#9071Vectors for use in an inducible coexpression system
#9072ANTIBODIES TO CEACAM1 AND KINASE INHIBITORS FOR TREATING BRAF-MUTATED CELLS
#9073Antibodies to CD40 with enhanced agonist activity
#9074Interferon receptor 1 antibodies and their uses
#9075Anti-EphA2 antibodies and methods of use thereof
#9076PD-1 antibody, antigen-binding fragment thereof, and medical application thereof
#9077Humanized anti-CD22 antibody
#9078Tight-binding agents and uses thereof
#9079METHOD OF TREATING CANCER
#9080Methods of determining whether anti-PACAP (adenylate cyclase-activating peptide) antibodies or anti-PACAP antigen binding fragments inhibit PACAP-associated photophobia or light aversion
#9081Use of an IL-17/IL-23 bispecific antibody for treating inflammation
#9082IL-18 binding molecules
#9083Anti-human proBDNF monoclonal antibody, and uses thereof in pains
#9084Human antibodies to fel D1 and methods of use thereof
#9085Methods of producing anti-C5a antibodies
#9086Antigen associated with lung cancers and lymphomas
#9087Human islet amyloid polypeptide (HIAPP) specific antibodies and uses thereof
#9088HUMANIZED, ANTI-N2 ANTIBODIES
#9089Humanized anti-tau(pS422) antibodies and methods of use
#9090Anti-Tau antibodies and methods of use
#9091Fc fusion proteins comprising novel linkers or arrangements
#9092PROTEINS COMPRISING AMINO-TERMINAL PROXIMAL SHIGA TOXIN A SUBUNIT EFFECTOR REGIONS AND CELL-TARGETING IMMUNOGLOBULIN-TYPE BINDING REGIONS
#9093Agents that engage antigen-presenting cells through dendritic cell asialoglycoprotein receptor (DC-ASGPR)
#9094Compositions and Methods of Use of Immunotoxins Comprising Ranpirnase (Rap) Show Potent Cytotoxic Activity
#9095High-throughput mouse model for optimizing antibody affinities
#9096CYS80 conjugated immunoglobulins
#9097Anti-PCSK9-GLP-1 fusions and methods for use
#9098Humanised anti kallikrein-2 antibody
#9099Fc-ENHANCED ANTI-WT1/HLA ANTIBODY
#9100Antibody drug conjugates (ADC) that bind to 158P1D7 proteins
#9101Multispecific NK engager proteins
#91024-1BB BINDING MOLECULES
#9103FULLY HUMAN ANTIBODIES AGAINST HUMAN 4-1BB
#9104Anti-OX40L antibodies and methods of treating graft versus host disease
#9105Anti-CLL-1 antibodies and methods of use
#9106Anti-CTLA-4 antibodies and methods of use thereof
#9107Human CD3 binding antibody
#9108BISPECIFIC CONSTRUCTS AND THEIR USE IN THE TREATMENT OF VARIOUS DISEASES
#9109Humanized and affinity matured antibodies to FcRH5 and methods of use
#9110Compositions comprising antibodies to LINGO or fragments thereof
#9111Human anti-IL-32 antibodies and methods of making and using the same
#9112Anti eotaxin-2 antibodies that recognize additional CCR3-binding chemokines
#9113Humanized antibodies specific to the protofibrillar form of the beta-amyloid peptide
#9114Methods for treating pain using antibodies to Kallidin and des-Arg-Kallidin
#9115Anti-complement factor C1q antibodies and uses thereof
#9116Methods, compositions and kits for treating a subject using a recombinant neutralizing binding protein
#9117Variant target binding agents and uses thereof
#9118POLYPEPTIDE CONSTRUCTS AND USES THEREOF
#9119Method of treating cancer using IL2R beta/common gamma chain antibodies
#9120Methods, compositions and kits for treating a subject using a recombinant heteromultimeric neutralizing binding protein
#9121Polynucleotides encoding VEGF/DLL4 binding agents
#9122High affinity antibody antagonists of interleukin-13 receptor alpha 1
#9123Methods of detecting a tumor expressing fibroblast growth factor receptor 2
#9124Human monoclonal antibodies to programmed death ligand 1 (PD-L1)
#9125ICOS binding proteins
#9126Anti-CD33 antibodies and methods for treatment of acute myeloid leukemia using the same
#9127Methods of treating an inflammatory condition or sensitivity to an allergen with anti-IL-33 antibodies
#9128Broadly neutralizing monoclonal antibodies against HIV-1 V1V2 Env region
#9129KIDNEY DISEASE TARGETS AND USES THEREOF
#9130Multi-specific polypeptide useful for localized tumor immunomodulation
#9131Use of anti-pacap antibodies and antigen binding fragments thereof for treatment, prevention, or inhibition of photophobia
#9132Methods for reducing immune responses
#9133ANTIBODIES THAT BIND TO HUMAN TAU AND ASSAY FOR QUANTIFYING HUMAN TAU USING THE ANTIBODIES
#9134Heterodimeric antibodies that bind CD3 and tumor antigens
#9135CA6 antigen-specific cytotoxic conjugate and methods of using the same
#9136Cancer therapy using CLDN6 target-directed antibodies in vivo
#9137Bispecific antibody binding to human TLR2 and human TLR4
#9138Anti-CD71 antibodies, activatable anti-CD71 antibodies, and methods of use thereof
#9139Antibody molecules having specificity for human OX40
#9140CX3CR1-binding polypeptides
#9141Anti-ITGA3 antibodies, activatable anti-ITGA3 antibodies, and methods of use thereof
#9142Lym-1 and Lym-2 targeted CAR cell immunotherapy
#9143ANTI-TIGIT ANTIBODIES
#9144Anti-CD166 antibodies, activatable anti-CD166 antibodies, and methods of use thereof
#9145Antagonists of IL-6 to raise albumin and/or lower CRP
#9146Antibodies targeting bone morphogenetic protein 9 (BMP9) and methods therefor
#9147Methods of treating a tauopathy
#9148Methods and compositions for targeting polyubiquitin
#9149Antibody-based therapy of transthyretin (TTR) amyloidosis and human-derived antibodies therefor
#9150Oligopeptide and methods for producing conjugates thereof
#9151Humanized anti-complement factor C1Q antibodies
#9152Immunoglobulin constant region Fc receptor binding agents
#9153Compositions for inducing antigen-specific tolerance
#9154Methods for induction of antigen-specific immune tolerance
#9155Compositions for generating immune tolerance by targeting erythrocytes
#9156Fluoroimmunoassay Method
#9157Acceptor framework for CDR grafting
#9158Anti human Notch4 antibody
#9159TLR3 BINDING AGENTS
#9160COMPOSITIONS AND METHODS OF USE FOR THERAPEUTIC ANTIBODIES
#9161Anti-CD40 antibodies
#9162Antibodies against OX40 and uses thereof
#9163Anti-OX40 antibodies
#9164Polynucleotides encoding an actriib antibody
#9165Isoform specific soluble FMS-like tyrosine kinase (sFlt) binding agents and uses thereof
#9166Prostate specific membrane antigen (PSMA) bispecific binding agents and uses thereof
#9167Antibodies comprising chimeric constant domains
#9168OPTIMIZED Fc VARIANTS AND METHODS FOR THEIR GENERATION
#9169Anti-transthyretin humanized antibody
#9170Camelid single-domain antibody directed against amyloid beta and methods for producing conjugates thereof
#9171Immunoglobulin against the anthrax toxin
#9172Antibodies against F glycoprotein of Hendra and Nipah viruses
#9173Optimized Fc variants and methods for their generation
#9174Tau peptides, anti-tau antibodies, and methods of use thereof
#9175Antibody drug conjugates (ADCs) with kinesin spindel protein (KSP)
#9176Compositions and methods to modulate cell activity
#9177Animal models and therapeutic molecules
#9178Trispecific binding proteins and methods of use
#9179Anti-mesothelin binding proteins
#9180Methods and Compositions for Antibody and Antibody-loaded Dendritic Cell Mediated Therapy
#9181OPTIMIZED FC VARIANTS
#9182Human C-FMS antigen binding proteins
#9183Formulation for anti-α4β7 antibody
#9184Methods of treating ulcerative colitis
#9185Immunomodulatory agents
#9186Treatment of PD-L1-negative melanoma using an anti-PD-1 antibody and an anti-CTLA-4 antibody
#9187Antibodies to human GDF8
#9188Agents that specifically bind matrilin-3 and their use
#9189ANTIBODIES DIRECTED AGAINST THE LukGH (LukAB) TOXIN OF STAPHYLOCOCCUS AUREUS AND ANTIBODY SEQUENCES
#9190Interleukin-10 fusion proteins and uses thereof
#9191Carrier-antibody compositions and methods of making and using the same
#9192Method of treatment of malignant solid tumors with afucosylated anti-FGFR2IIIb antibodies
#9193BACTERIAL INFLUENCE OF HOST FEEDING AND EMOTION VIA CLPB PROTEIN MIMICRY OF A-MSH
#9194Carrier-antibody compositions and methods of making and using the same
#9195Anti-tissue factor monoclonal antibody
#9196Anti-human TROP-2 antibody having an antitumor activity in vivo
#9197CHIMERIC ANTIGEN RECEPTORS (CARs) HAVING MUTATIONS IN THE FC SPACER REGION AND METHODS FOR THEIR USE
#9198Anti-FZD10 monoclonal antibodies and methods for their use
#9199Multivalent antibodies
#9200Antibodies against TL1a and uses thereof
#9201Baff selective binding compounds and related methods
#9202Anti-human RANKL antibody, humanized antibody of the same, and pharmaceutical composition and use thereof
#9203Methods for the preparation of compounds directed against interleukin-6 receptor (IL-6R)
#9204Antibodies against canine PD-1
#9205Humanized or chimeric CD3 antibodies
#9206Anti-IL-23 antibodies
#9207Antibodies directed against interleukin-33 (IL-33) and methods of making and using
#9208Antigenic GM-CSF peptides and antibodies to GM-CSF
#9209Antigen binding proteins
#9210Targeting CLPTM1L for treatment and prevention of cancer
#9211Antibody targeting cell surface deposited complement protein C3d and use thereof
#9212AGLYCOSYLATED ANTI-Bb ANTIBODIES AND USES THEREOF
#9213AGLYCOSYLATED ANTI-C3b ANTIBODIES AND USES THEREOF
#9214Antibodies specific for enteroviruses that infect humans
#9215Antibody therapeutics that bind PSMA
#9216CD37-binding molecules and immunoconjugates thereof
#9217NOVEL ANTI ADAM17 ANTIBODY AND ITS USE FOR THE TREATMENT OF CANCER
#9218Recombinant obligate anaerobic gram-positive bacteria
#9219Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (CSF1R)
#9220Methods for treating rheumatoid arthritis by administering IL-6 receptor antibodies
#9221BIOLOGICAL PRODUCTS
#9222Use of IL-1 β binding antibodies for treating peripheral arterial disease
#9223TNFa-IL-17 bispecific antibodies
#9224Aβ conformer selective anti-Aβ globulomer monoclonal antibodies
#9225METHODS OF TREATMENT FOR GUILLAIN-BARRE SYNDROME
#9226Antibody possessing an affinity for epithelial secretory and nervous tissue, as well as tumour tissue derived from these tissues as well as the use thereof
#9227Methods of preparation of conjugates
#9228Nanoparticle complexes of albumin, paclitaxel, and panitumumab for treatment of cancer
#9229Transgenic transchromosomal rodents for making human antibodies
#9230Antibody identification by lineage analysis
#9231Methods of treatment with bispecific antibodies binding to beta-klotho and fibroblast growth factor receptor 1
#9232MET-BINDING AGENTS AND USES THEREOF
#9233Neuregulin allosteric anti-HER3 antibody
#9234Neutralizing prolactin receptor antibody Mat3 and its therapeutic use
#9235Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (CSF1R)
#9236Anti-human BDCA-2 antibody
#9237Anti-CD19 antibodies
#9238Anti-PD-1 antibodies
#9239Caninized murine antibodies to human PD-1
#9240Antibodies to tumor endothelial marker 8
#9241Adrenomedullin binder for use in therapy of cancer
#9242Anti-aP2 antibodies and antigen binding agents to treat metabolic disorders
#9243Optimized Fc variants and methods for their generation
#9244Chimeric virus-like particles incorporating fusion GPI anchored GM-CSF and IL-4 conjugates
#9245Combination comprising anti-fibroblast growth factor receptor 2 (FGFR2) antibody and a tyrosine kinase inhibitor
#9246Dual specificity antibody fusions
#9247Polynucleotides encoding anti-kit antibodies
#9248Antigen binding proteins that bind ErbB3
#9249Human mesothelin chimeric antigen receptors and uses thereof
#9250Anti-CD40 antibodies
#9251Methods for treating or preventing migraine headache
#9252ANTI-GLUCAGON RECEPTOR ANTIBODIES AND METHODS OF USE THEREOF
#9253Compositions and methods for inhibiting PDGFRbeta and VEGF-A
#9254Anti-PDL1 antibodies, activatable anti-PDL1 antibodies, and methods of thereof
#9255Caninized antibodies
#9256Histidine engineered light chain antibodies and genetically modified non-human animals for generating same
#9257IL-31 monoclonal antibody formulations
#9258Monoclonal antibodies that bind both IL-17A and IL-17F
#9259Anti-Complement factor H antibodies
#9260Nanoparticle complexes of anti-CD20 antibodies, albumin and paclitaxel
#9261Antigen-binding molecules, the antigen-binding activity of which varies according to the concentration of compounds, and libraries of said molecules
#9262Directed evolution of multivalent glycopeptides that tightly bind to target proteins
#9263Peptides and uses thereof
#9264Multivalent glycopeptides that tightly bind to target proteins
#9265ACCEPTOR FRAMEWORK FOR CDR GRAFTING
#9266Anti-HER2 antibody and conjugate thereof
#9267ANTIBODIES FOR DIAGNOSIS OF ACUTE MYELOID LEUKEMIA
#9268Anti-EGFRvIII antibodies and uses thereof
#9269NEUROPILIN ANTAGONISTS
#9270Antibodies to ICOS
#9271Antibodies to human programmed death receptor PD-1
#9272Antibodies against kidney associated antigen 1 and antigen binding fragments thereof
#9273Anti-PACAP antibodies
#9274HUMAN ANTI-NGF NEUTRALIZING ANTIBODIES AS SELECTIVE NGF PATHWAY INHIBITORS
#9275Anti-PHF-tau antibodies and their uses
#9276Nucleic acids encoding anti-polyubiquitin antibodies
#9277Methods of diagnosing tau-protein-associated disease
#9278Optimized Fc variants
#9279PERTUSSIS ANTIBODIES AND USES THEREOF
#9280Insertable variable fragments of antibodies and modified α1-α2 domains of NKG2D ligands
#9281Antibody-SN-38 immunoconjugates with a CL2A linker
#9282Anti-TROP2 antibody-drug conjugate
#9283Antibody therapeutics that bind CD38
#9284Engineered immunoglobulin Fc polypeptides displaying improved complement activation
#9285Therapeutic antibodies and their uses
#9286Chimeric antigen receptors targeting B-cell maturation antigen
#9287Methods of treating neuropathic pain with specific binding members for NGF
#9288Anti-pseudomonas Psl binding molecules and uses thereof
#9289Inhibitors of type 2 vascular endothelial growth factor receptors
#9290Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
#9291HCV core lipid binding domain monoclonal antibodies
#9292Fabs-in-tandem immunoglobulin and uses thereof
#9293Anti-CD20− / anti-BAFF bispecific antibodies
#9294Fabs-in-tandem immunoglobulin and uses thereof
#9295Compositions and methods for treatment and detection of cancers
#9296Antibodies
#9297Polypeptides
#9298CANCER BIOMARKERS AND USES THEREOF
#9299Bispecific antigen-binding constructs targeting HER2
#9300Anti-claudin antibodies and methods of use