97314 ⎘
Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
CAL-T constructs and uses thereof
#1502RECOMBINANT VECTOR CARRYING DISULFIDE BOND ISOMERASE SIGNAL PEPTIDE AND USE THEREOF
#1503Materials and methods for engineering cells and uses thereof in immuno-oncology
#1504PLAP-CAR-effector cells
#1505CARTYRIN COMPOSITIONS AND METHODS FOR USE
#1506Constructs specifically recognizing glypican 3 and uses thereof
#1507Anti-CD20 antibody and uses thereof
#1508Cells expressing chimeric activating receptors and chimeric stimulating receptors and uses thereof
#1509Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of MPL
#1510VACCINE COMPOSITIONS AND METHODS FOR ENHANCED ANTIGEN-SPECIFIC VACCINATION
#1511NK-92 Bone and Brain targeting
#1512METHODS FOR IMPROVING ADOPTIVE CELL THERAPY
#1513METHODS FOR PREPARING CELLS FOR ADOPTIVE T CELL THERAPY
#1514CHIMERIC RECEPTORS AND METHODS OF USE THEREOF
#1515Chimeric antibody/T-cell receptor constructs and uses thereof
#1516Humanized anti-GDNF family alpha-receptor 4 (GRF-alpha-4) antibodies and chimeric antigen receptors (CARs)
#1517Cell comprising a chimeric antigen receptor or a transgenic T-cell receptor and comprising a chimeric TNF receptor
#1518COMPOSITIONS AND METHODS OF PHOSPHOLIPASE A2 RECEPTOR CHIMERIC AUTOANTIBODY RECEPTOR T CELLS
#1519Therapeutic agents
#1520METHODS AND COMPOSITIONS FOR TREATMENT OF HEMOPHILIA
#1521NUCLEIC ACID CONSTRUCTS COMPRISING GENE EDITING MULTI-SITES AND USES THEREOF
#1522CHIMERIC ANTIGEN RECEPTORS AGAINST SENESCENT CELLS AND USES THEREOF
#1523REGULATABLE CHIMERIC ANTIGEN RECEPTOR
#1524Chimeric TIM4 receptors and uses thereof
#1525Materials and methods for engineering cells and uses thereof in immuno-oncology
#1526Compositions comprising polypeptides having xylanase activity and polypeptides having arabinofuranosidase activity
#1527Reducing immune tolerance induced by PD-L1
#1528CD19-CD20 BISPECIFIC AND DUAL PASSWAY CAR-T AND METHODS FOR USE THEREOF
#1529COMPOSITIONS AND METHODS FOR DELIVERY AND EXPRESSION OF SMALL INHIBITORY PEPTIDES AND USE THEREOF
#1530Universal donor cells
#1531HLA-G AS A NOVEL TARGET FOR CAR T-CELL IMMUNOTHERAPY
#1532Immune cells engineered to express CD19-directed chimeric antigen receptors and uses thereof in immunotherapy
#1533CD19-directed chimeric antigen receptors and uses thereof in immunotherapy
#1534Anti-CCT5 binding molecules and chimeric antigen receptors comprising the same
#1535Universal donor cells
#1536Universal donor cells
#1537Universal donor cells
#1538Peptide-MHC compacts
#1539Pooling signaling and costimulatory domains in B7H6 chimeric antigen receptor
#1540Multi-chain chimeric polypeptides and uses thereof
#1541Multi-chain chimeric polypeptides and uses thereof
#1542Universal donor cells
#1543METHODS AND COMPOSITIONS OF CYTOTOXIC T CELL DEPLETION
#1544CA2 compositions and methods for tunable regulation
#1545Synthetic notch receptor protein for modulating gene expression
#1546Chimeric antigen receptors and methods of use thereof
#1547Modified N-810 and Methods Therefor
#1548Cancer immunotherapy using CD19-directed chimeric antigen receptors
#1549Methods and compositions for treating cancer
#1550Enhanced immune cells using dual shRNA and composition including the same
#1551Adhesion Receptor Constructs and Uses Thereof in Natural Killer Cell Immunotherapy
#1552IMMUNE CELLS EXPRESSING A CHIMERIC ANTIGEN RECEPTOR
#1553Modulation of SLAMF6 splice variants for cancer therapy
#1554CAR T CELL THERAPIES WITH ENHANCED EFFICACY
#1555DNase therapy for intravascular accumulation of extracellular DNA
#1556Human alpha-folate receptor chimeric antigen receptor
#1557SYSTEM AND METHODS RELATING TO CHIMERIC AUTOANTIBODY RECEPTORS
#1558ENGINEERED VEGF VARIANTS FOR RETINAL NEUROPROTECTION, PROMOTION OF AXON GROWTH AND AXON REGENERATION
#1559Molecular switch-mediated control of engineered cells
#1560CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF
#1561Expression of phytase in
#1562Compositions for Treating Ectopic Calcification Disorders, and Methods Using Same
#1563Methods of treating T cell exhaustion by inhibiting or modulating T cell receptor signaling
#1564CD83-BINDING CHIMERIC ANTIGEN RECEPTORS
#1565POLYPEPTIDES AND METHODS
#1566APOM-FC FUSION PROTEINS AND USES THEREOF
#1567SINGLE-CHAIN CD40-RECEPTOR AGONIST PROTEINS
#1568METHOD FOR SECRETORY PRODUCTION OF PROTEIN
#1569MODULATING T CELL FUNCTION AND RESPONSE
#1570Target recognition motifs and uses thereof
#1571NKG2D CHIMERIC ANTIGEN RECEPTORS
#1572EXPRESSION VECTORS FOR CHIMERIC ENGULFMENT RECEPTORS, GENETICALLY MODIFIED HOST CELLS, AND USES THEREOF
#1573CHIMERIC TIM-3 FUSION PROTEIN
#1574Cellular immunotherapy compositions and uses thereof
#1575Polypeptides having xylanase activity and polynucleotides encoding same
#1576Constructs trageting CD22 and uses thereof
#1577ANTI-CD33 CHIMERIC ANTIGEN RECEPTORS AND THEIR USES
#1578Neutralization of Human Cytokines with Membrane-Bound Anti-Cytokine Non-Signaling Binders Expressed in Immune Cells
#1579METHODS OF PRODUCING CELLS EXPRESSING A RECOMBINANT RECEPTOR AND RELATED COMPOSITIONS
#1580CELLULAR SIGNALING DOMAIN ENGINEERING IN CHIMERIC ANTIGEN RECEPTOR-MODIFIED REGULATORY T CELLS
#1581Polypeptides comprising a modified bacteriophage G3P amino acid sequence lacking a glycosylation signal
#1582Chimeric inhibitor molecules of complement activation
#1583Compositions and methods for T cell delivery of therapeutic molecules
#1584LONG-ACTING IGF-1 OR IGF-1 VARIANTS AND METHODS OF PRODUCING SAME
#1585NOVEL HUMANIZED ANTI-CD19 CHIMERIC ANTIGEN RECEPTOR, ITS NUCELIC ACID SEQUENCE AND ITS PREPARATION
#1586Transgene genetic tags and methods of use
#1587COMPOSITIONS AND METHODS FOR TREATING PARKINSON'S DISEASE
#1588Trophoblast glycoprotein (5T4, TPBG) specific chimeric antigen receptors for cancer immunotherapy
#1589Human mesothelin chimeric antigen receptors and uses thereof
#1590ANTI CD30 CHIMERIC ANTIGEN RECEPTOR AND ITS USE
#1591GENETICALLY MODIFIED CELLS AND METHOD FOR PRODUCING SAME
#1592PD-1 and PD-L1 binding agents
#1593Exosomes for immuno-oncology and anti-inflammatory therapy
#1594COMPOSITIONS AND METHODS FOR INHIBITION OF ALPHAVIRUS INFECTION
#1595Materials and methods for engineering cells and uses thereof in immuno-oncology
#1596Materials and methods for engineering cells and uses thereof in immuno-oncology
#1597OPTIMIZED LENTIVIRAL TRANSFER VECTORS AND USES THEREOF
#1598DNase therapy for intravascular accumulation of extracellular DNA
#1599IL-33 SECRETING IMMUNORESPONSIVE CELLS AND USES THEREOF
#1600Dimeric antigen receptors
#1601Humanized BCMA antibody and BCMA-CAR-T cells
#1602CAR-T CELLS AND AUTOIMMUNE DISEASES
#1603IMPROVED T CELL COMPOSITIONS AND METHODS
#1604Compositions and methods for treating cancer with DuoCARs
#1605Recombinant human replication-deficient adenovirus comprising a modified nucleic acid encoding the Marburg virus envelope glycoprotein
#1606Filovirus consensus antigens, nucleic acid constructs and vaccines made therefrom, and methods of using same
#1607COMPOSITIONS TO DISRUPT PROTEIN KINASE A ANCHORING AND USES THEREOF
#1608EXPRESSION AND SECRETION SYSTEM
#1609Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
#1610LAMP constructs
#1611ELIMINATION OF CD19-POSITIVE LYMPHOID MALIGNANCIES BY CD19-CAR EXPRESSING NK CELLS
#1612Targeting B cell activating factor receptor (BAFF-R) using ligand-based chimeric antigen receptor (CAR)-T cells
#1613Ligand discovery and gene delivery via retroviral surface display
#1614Engineered Expression of Cell Surface and Secreted Sialidase by CAR T Cells for Increased Efficacy in Solid Tumors
#1615CELLULAR BASED THERAPIES TARGETING DISEASE-ASSOCIATED MOLECULAR MEDIATORS OF FIBROTIC, INFLAMMATORY AND AUTOIMMUNE CONDITIONS
#1616T-cell modulatory multimeric polypeptide with conjugation sites and methods of use thereof
#1617Single-chain TNF receptor 2 agonist fusion proteins
#1618DOMINANT NEGATIVE LIGAND CHIMERIC ANTIGEN RECEPTOR SYSTEMS
#1619Chimeric peptides with an antimicrobial domain and an inorganic binding domain
#1620Methods for preparing modified von Willebrand factor
#1621Compositions and methods for TCR reprogramming using fusion proteins
#1622BCMA-targeted chimeric antigen receptor as well as preparation method therefor and application thereof
#1623Method of redirecting t cells to treat HIV infection
#1624Compositions and methods for TCR reprogramming using fusion proteins
#1625Modified immune cells and uses thereof
#1626XCR1 BINDING AGENTS AND USES THEREOF
#1627ANTI-CANCER DNA VACCINE EMPLOYING PLASMIDS ENCODING SIGNAL SEQUENCE, MUTANT ONCOPROTEIN ANTIGEN, AND HEAT SHOCK PROTEIN
#1628Regulatory T cell expressing a chimeric antigen receptor
#1629USE AND PRODUCTION OF ENGINEERED IMMUNE CELLS TO DISRUPT NFAT-AP1 PATHWAY TRANSCRIPTION FACTORS
#1630TISSUE FACTOR-TARGETING CAR-NK AND CAR-T CELL THERAPY
#1631Engineered DNase enzymes and use in therapy
#1632Activation of APC in immunotherapy
#1633METHODS FOR ENHANCING AND MAINTAINING CAR-T CELL EFFICACY
#1634USES OF AMPHIPHILES IN IMMUNE CELL THERAPY AND COMPOSITIONS THEREFOR
#1635Compositions and methods for targeting CLEC12A-expressing cancers
#1636Prostate-specific membrane antigen cars and methods of use thereof
#1637Engineered phagocytic receptor compositions and methods of use thereof
#1638Engineered phagocytic receptor compositions and methods of use thereof
#1639Protease-resistant systems for polypeptide display and methods of making and using thereof
#1640Compositions and methods for selective protein degradation
#1641Compositions and methods for targeting γδ T cells with chimeric antigen receptors
#1642Reducing immune inhibition induced by SIGLEC-15
#1643Promoter polynucleotide, signal polypeptide and use thereof
#1644CHIMERIC ANTIGEN RECEPTOR (CAR) SIGNALLING SYSTEM
#1645Materials and methods for the synthesis of error-minimized nucleic acid molecules
#1646Force sensor cleavage domain containing chimeric polypeptides and methods of use thereof
#1647Therapeutic agents
#1648SINGLE-CHAIN LIGHT RECEPTOR AGONIST PROTEINS
#1649Fusion proteins and combination vaccines comprising Protein E and Pilin A
#1650Materials and methods for engineering cells and uses thereof in immuno-oncology
#1651METHODS AND COMPOSITIONS RELATING TO ENGINEERED REGULATORY T CELLS
#1652NOVEL CHIMERIC ANTIGEN RECEPTORS AND LIBRARIES
#1653Methods of treatments using antigen-binding proteins targeting CD56
#1654Methods and compositions for improved expression of recombinant proteins
#1655Recombinant Protein
#1656ENGINEERED CELLS FOR ADOPTIVE CELL THERAPY
#1657Anti-CD70 chimeric antigen receptors
#1658Enhanced chimeric antigen receptors and uses thereof
#1659Methods and compositions for treating and preventing HIV
#1660Chimeric engulfment receptor molecules and methods of use
#1661Chimeric antigen receptors targeted to PSCA
#1662Thymic stromal lymphopoietin receptor-specific chimeric antigen receptors and methods using same
#1663CTLA-4 variant immunomodulatory proteins and uses thereof
#1664Chimeric Natural Killer Cell Receptors and Method of Using Thereof
#1665Chimeric antigen receptor (CAR) modulation
#1666COMPOSITIONS AND METHODS FOR TARGETED TUMOR IMMUNOTHERAPY
#1667PRIMARY CELL GENE EDITING
#1668CDKL5 EXPRESSION VARIANTS AND CDKL5 FUSION PROTEINS
#1669ROR1 antibody compositions and related methods
#1670Immunoassays and engineered proteins for monitoring antibody treatments to the immune checkpoint inhibitors PD1 and PD-L1
#1671Cell
#1672Compositions comprising polypeptides having xylanase activity and polypeptides having arabinofuranosidase activity
#1673Cell secreted minibodies and uses thereof
#1674Chimeric antigen receptors, compositions, and methods
#1675Compositions and methods for immunomodulation in an organism
#1676Constitutively active chimeric cytokine receptors
#1677Genetically engineered vaccinia viruses
#1678Targeted protein degradation
#1679Anti-HLA-A2 antibodies, related chimeric antigen receptors, and uses thereof
#1680Anti-hla-A2 antibodies and methods of using the same
#1681M971 chimeric antigen receptors
#1682VARIANT ICOS LIGAND IMMUNOMODULATORY PROTEINS AND RELATED COMPOSITIONS AND METHODS
#1683Therapeutic agents
#1684Compositions and methods for inhibition of lineage specific antigens
#1685Nucleic acid molecules encoding chimeric antigen receptors targeting B-cell maturation antigen and uses thereof
#1686Methods of using chimeric antigen receptors targeting B-cell maturation antigen and uses thereof
#1687Compositions and methods for improved T cells
#1688Compositions and methods for treating cancer
#1689Rationally-designed synthetic peptide shuttle agents for delivering polypeptide cargos from an extracellular space to the cytosol and/or nucleus of a target eukaryotic cell, uses thereof, methods and kits relating to same
#1690GAMMA DELTA T CELLS AND USES THEREOF
#1691METHODS AND COMPOSITIONS FOR ALLEVIATING CYTOKINE RELEASE SYNDROME
#1692CD33 exon 2 deficient donor stem cells for use with CD33 targeting agents
#1693Universal platform for preparing an inhibitory chimeric antigen receptor (iCAR)
#1694Influenza virus-like particle production in plants
#1695Antibody chemically induced dimerizer (AbCID) as molecular switches for regulating cellular therapies
#1696Cell
#1697PROTEIN SECRETORY FACTOR WITH HIGH SECRETORY EFFICIENCY AND AN EXPRESSION VECTOR COMPRISING THE SAME
#1698Chimeric Antigen Receptor
#1699Modified monocytes/macrophage expressing chimeric antigen receptors and uses thereof
#1700Chimeric antigen receptors targeting abnormal glycobiology
#1701Headless hemagglutin influenza vaccine
#1702Human cytomegalovirus RNA vaccines
#1703Method of reducing mesothelin-expressing tumor burden by administration of T cells comprising mesothelin-targeted chimeric antigen receptors
#1704MODIFIED EPIDERMAL GROWTH FACTOR RECEPTOR PEPTIDES FOR USE IN GENETICALLY-MODIFIED CELLS
#1705CYCLIC GALANIN-ANALOGS AND USES THEREOF
#1706Cancer treatment
#1707T-cells expressing anti-LIV1 chimeric antigen receptor
#1708GPRC5D chimeric antigen receptors and cells expressing the same
#1709CD8 binding agents
#1710Compositions and methods for treating cancer with anti-mesothelin immunotherapy
#1711Compositions and methods for treating cancer with DuoCARs
#1712Codon optimized IL-15 and IL-15R-alpha genes for expression in mammalian cells
#1713MGAT1-Deficient Cells for Production of Vaccines and Biopharmaceutical Products
#1714Modular polypeptide libraries and methods of making and using same
#1715Compositions and methods for targeting CD33-expressing cancers
#1716Chimeric antigen receptors (CARs), compositions and methods thereof
#1717Recombinant PETase producing strain, recombinant MHETase producing strain, and composition for degrading PET containing the same
#1718Integral membrane protein display on poxvirus extracellular enveloped virions
#1719Chimeric antigen receptors and CAR-T cells that bind CXCR5 and methods of use thereof to treat medical disorders
#1720Chimeric antigen receptors with enhanced NFκB signaling
#1721Compositions and methods for modulating immune cells
#1722TREATMENT OF CANCER USING A CLL-1 CHIMERIC ANTIGEN RECEPTOR
#1723Modified urokinase-type plasminogen activator polypeptides and methods of use
#1724T CELLS EXPRESSING A CHIMERIC ANTIGEN RECEPTOR
#1725COMPOSITIONS AND METHODS FOR TCR REPROGRAMMING USING FUSION PROTEINS
#1726Selectively controllable cleavable linkers
#1727CELL COMPRISING A CHIMERIC ANTIGEN RECEPTOR (CAR)
#1728Mutant tumor necrosis factor receptor superfamily (TNFsfR) ligands and methods of making and using same
#1729BAFF-R antibodies and uses thereof
#1730Nanonets and spherical particles
#1731DNA vaccine against virus of Yellow Fever
#1732Primary cell gene editing
#1733Methods and compositions for secretion of heterologous polypeptides
#1734Chimeric transcription factor variants with augmented sensitivity to drug ligand induction of transgene expression in mammalian cells
#1735OCTS technology-based pancreatic cancer and malignant mesothelioma CAR-T therapeutic vector, construction method therefor, and use thereof
#1736Malignant glioma CAR-T therapeutic vector based on OCTS technology, and construction method and application thereof
#1737ANTIBODY-COUPLED T CELL RECEPTOR CONSTRUCTS AND THERAPEUTIC USES THEREOF
#1738Nsp-interleukin-10 proteins and uses thereof
#1739Fusion proteins for inhibiting angiogenesis
#1740Modified cell with enhanced migration capability
#1741Immunologic effector cell of targeted CLD18A2, and preparation method and use thereof
#1742Primary cell gene editing
#1743CD123-binding chimeric antigen receptors
#1744HLA-DR CAR-T COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME
#1745Rapid elicitation of broadly neutralizing antibodies to HIV Env
#1746Compositions and methods of use for treating metabolic disorders
#1747Anti-epidermal growth factor receptor variant III chimeric antigen receptors and use of same for the treatment of cancer
#1748Methods of producing aggregate-free monomeric diphtheria toxin fusion proteins and therapeutic uses
#1749Compositions and methods for treating cancer with anti-CD22 immunotherapy
#1750Modified cell expressing therapeutic agent and uses thereof
#1751METHODS AND COMPOSITION FOR SECRETION OF HETEROLOGOUS POLYPEPTIDES
#1752HLA-restricted VCX/Y peptides and T cell receptors and use thereof
#1753COMPOSITIONS AND METHOD FOR IDENTIFYING ENZYME AND TRANSPORT PROTEIN INHIBITORS
#1754Anti-PTK7 immune cell cancer therapy
#1755PROTEASE BASED SWITCH CHIMERIC ANTIGEN RECEPTORS FOR SAFER CELL IMMUNOTHERAPY
#1756Universal non-classical MHC I vaccines: HLA-E-restricted antigenic peptides as universal vaccines to treat allergy, inflammation, autoimmune and infectious diseases, and cancers
#1757Non-natural NKG2D receptors that do not directly signal the cells to which they are attached
#1758Targeting modules for universal chimeric antigen receptor expressing immune cells and use in the treatment of cancer infections and autoimmune disorders
#1759Truncated NKG2D chimeric receptors and uses thereof in natural killer cell immunotherapy
#1760Proteins and peptide tags with enhanced rate of spontaneous isopeptide bond formation and uses thereof
#1761Herpes simplex virus vaccine
#1762EHRLICHIA RUMINANTIUM IMMUNOGENIC COMPOSITIONS AND METHODS OF USING THEREOF
#1763Chimeric antigen receptors with mutated CD28 costimulatory domains
#1764Elimination of CD19-positive lymphoid malignancies by CD19-CAR expressing NK cells
#1765Chimeric antibody immune effector cell engagers and methods of use thereof
#1766Monoclonal antibody targeting a unique sialoglycosylated cancer-associated epitope of CD43
#1767Compositions and methods for treating cancer with anti-CD19 immunotherapy
#1768Methods of exogenous drug activation of chemical-induced signaling complexes expressed in engineered cells in vitro and in vivo
#1769Virulence attenuated bacteria based protein delivery
#1770COMPOSITIONS AND METHODS FOR ADOPTIVE CELL THERAPIES
#1771CHIMERIC RECEPTORS AND METHODS OF USE THEREOF
#1772Cells expressing chimeric activating receptors and chimeric stimulating receptors and uses thereof
#1773Methods and compositions for increasing red blood cells
#1774Articles of manufacture and methods related to toxicity associated with cell therapy
#1775Methods of making T cell compositions
#1776Compositions and methods for treating cancer with anti-CD19/CD20 immunotherapy
#1777CHIMERIC ANTIGEN RECEPTORS (CAR) AND METHODS FOR MAKING AND USING THE SAME
#1778Methods and compositions for treating and preventing HIV
#1779PDE5 compositions and methods for immunotherapy
#1780Anti-CD30 antibodies and methods for treating CD30+ cancer
#1781Methods and systems to produce lignin-modifying enzymes and uses thereof
#1782Process for the purification of recombinant antibody fragments
#1783THERAPEUTIC CELLS
#1784Targeted chimeric proteins and uses thereof
#1785Chimeric antigen receptor cells targeting ROBO1, preparation method and use thereof
#1786Compositions and methods for treating cancer with anti-CD19/CD22 immunotherapy
#1787BIOMARKERS AND CAR T CELL THERAPIES WITH ENHANCED EFFICACY
#1788HUMAN APPLICATION OF ENGINEERED CHIMERIC ANTIGEN RECEPTOR (CAR) T-CELLS
#1789Immune cells expressing engineered antigen receptors
#1790CRISPR-Cas9 Knock-out of SHP-1/2 to Reduce T cell Exhaustion in Adoptive Cell Therapy
#1791Compositions and methods for targeting stromal cells for the treatment of cancer
#1792BCMA chimeric antigen receptors
#1793Chimeric antigen receptors and methods of use
#1794METHODS FOR DETERMINING CAR-T CELLS DOSING
#1795Chimeric antigen receptors targeting BCMA and methods of use thereof
#1796Targeted engineered interferon and uses thereof
#1797CAR T therapy through uses of co-stimulation
#1798Multi-chain chimeric polypeptides and uses thereof
#1799Synthetic protein circuits detecting signal transducer activity
#1800Targeted disruption of the MHC cell receptor