ClassID:

97319

C07K2319/036 - CPC Classification

Classification description:

Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion

Recent Application in this class:
#1
20260109937
2026-04-23

ENGINEERED MICROORGANISMS WITH ENHANCED PROTEIN EXPRESSION AND SECRETION

#2
20260097087
2026-04-09

RECOMBINANT FUSION POLYPEPTIDES FOR SECRETING SOLUBLE, HETEROLOGOUS CARGO

#3
20260085107
2026-03-26

PRODUCTION OF PROTEINS, INCLUDING SECRETED PROTEINS

#4
20250368691
2025-12-04

Virulence Attenuated Bacteria Based Protein Delivery

#5
20250134990
2025-05-01

IMMUNOGENIC COMPOSITIONS AND USES THEREOF

#6
20250122252
2025-04-17

COMPOSITIONS AND METHODS FOR PRODUCING HIGH SECRETED YIELDS OF RECOMBINANT PROTEINS

#7
20240376512
2024-11-14

OVER EXPRESSION OF FOLDASES AND CHAPERONES IMPROVES PROTEIN PRODUCTION

#8
20240344082
2024-10-17

VIRAL CONSTRUCTS FOR USE IN ENHANCING T-CELL PRIMING DURING VACCINATION

#9
20240294899
2024-09-05

PREPARATION OF LIBRARIES OF PROTEIN VARIANTS EXPRESSED IN EUKARYOTIC CELLS AND USE FOR SELECTING BINDING MOLECULES

#10
20240277766
2024-08-22

ARMED CHIMERIC RECEPTORS AND METHODS OF USE THEREOF

#11
20240269232
2024-08-15

A MODIFIED HLA-B57 WITH INCREASED EXPRESSION LEVELS

#12
20240190925
2024-06-13

SIGNAL SEQUENCE THAT INDUCES PROTEIN SECRETION IN INTESTINAL MICROBIOME

#13
20240180974
2024-06-06

MICROORGANISMS PROGRAMMED TO PRODUCE IMMUNE MODULATORS AND ANTI-CANCER THERAPEUTICS IN TUMOR CELLS

#14
20240165168
2024-05-23

Engineered bacteria secreting therapeutic proteins and methods of use thereof

#15
20240141363
2024-05-02

SIGNAL PEPTIDES FOR INCREASED PROTEIN SECRETION

#16
20240092869
2024-03-21

EXPRESSION OF THE HUMAN LEKTI GENE FROM THE CHROMOSOME OF STAPHYLOCOCCUS EPIDERMIDIS

#17
20230382956
2023-11-30

BACTERIA BASED PROTEIN DELIVERY

#18
20230357781
2023-11-09

LISTERIA-BASED COMPOSITIONS COMPRISING A PEPTIDE MINIGENE EXPRESSION SYSTEM AND METHODS OF USE THEREOF

#19
20230277684
2023-09-07

MODIFIED UBE3A GENE FOR A GENE THERAPY APPROACH FOR ANGELMAN SYNDROME

#20
20230250138
2023-08-10

Virulence Attenuated Bacteria Based Protein Delivery

#21
20230235004
2023-07-27

TISSUE TARGETED IMMUNOTOLERANCE WITH PD-1 AGONISTS OR IL-2 MUTEINS

#22
20230159906
2023-05-25

Protease-controlled Secretion and Display of Intercellular Signals

#23
20230013523
2023-01-19

Mucoadhesive microorganism

#24
20220348636
2022-11-03

METHOD FOR PRODUCING FUSION PROTEIN HAVING IGG FC DOMAIN

#25
20220306706
2022-09-29

Compositions and methods for producing high secreted yields of recombinant proteins

#26
20220282264
2022-09-08

Endotoxin-free Production of Recombinant Subunit Vaccine Components

#27
20220280575
2022-09-08

Engineered bacteria secreting therapeutic proteins and methods of use thereof

#28
20220260563
2022-08-18

COMPOSITIONS AND METHODS FOR BINDING ANTIBODIES AND INHIBITING NEUTRALIZING ANTIBODIES

#29
20220152212
2022-05-19

Systems, Methods, And Compositions For The Generation Of Water-Soluble Cannabinoids Utilizing Fatty-Acid Binding Proteins And Fatty-Acid Binding-Like Proteins As Cannabinoid-Carriers

#30
20220073579
2022-03-10

DECORIN COMPOSITIONS AND USE THEREOF

#31
20220002822
2022-01-06

CELL LINES EXPRESSING INSERTED SECRETABLE REPORTER GENES AT MULTIPLE STAGES OF DIFFERENTIATION

#32
20210246457
2021-08-12

Listeria-based compositions comprising a peptide minigene expression system and methods of use thereof

#33
20210230235
2021-07-29

Compositions and methods for producing high secreted yields of recombinant proteins

#34
20210108221
2021-04-15

Endostatin fragments and variants for use in treating fibrosis

#35
20210070815
2021-03-11

Mucoadhesive microorganism

#36
20200332286
2020-10-22

Materials and methods for the synthesis of error-minimized nucleic acid molecules

#37
20200291078
2020-09-17

Method of making recombinant silk and silk-amyloid hybrid proteins using bacteria

#38
20200262905
2020-08-20

DUAL PDGF/VEGF ANTAGONISTS

#39
20200165597
2020-05-28

PREPARATION OF LIBRARIES OF PROTEIN VARIANTS EXPRESSED IN EUKARYOTIC CELLS AND USE FOR SELECTING BINDING MOLECULES

#40
20200165596
2020-05-28

Preparation of libraries of protein variants expressed in eukaryotic cells and use for selecting binding molecules

#41
20200165595
2020-05-28

Preparation of libraries of protein variants expressed in eukaryotic cells and use for selecting binding molecules

#42
20200123207
2020-04-23

Virulence attenuated bacteria based protein delivery

#43
20200038523
2020-02-06

PSMA-specific binding proteins

#44
20190256577
2019-08-22

Process for preparation of secretory IgA and secretory IgM

#45
20190248851
2019-08-15

RECOMBINANT NEL-LIKE (MELL) PROTEIN PRODUCTION

#46
20190225988
2019-07-25

Genomic integration of DNA fragments in fungal host cells

#47
20190201457
2019-07-04

Engineered bacteria secreting therapeutic proteins and methods of use thereof

#48
20190194670
2019-06-27

Bacteria-based protein delivery

#49
20190194292
2019-06-27

Enveloped virus resistant to complement inactivation for the treatment of cancer

#50
20190194267
2019-06-27

Mucoadhesive microorganism

#51
20190160115
2019-05-30

Microorganisms programmed to produce immune modulators and anti-cancer therapeutics in tumor cells

#52
20190119692
2019-04-25

Multi-copy strategy for high-titer and high-purity production of multi-subunit proteins such as antibodies in transformed microbes such as

#53
20190085037
2019-03-21

gene with lepidopteran activity

#54
20190002891
2019-01-03

Listeria-based compositions comprising a peptide minigene expression system and methods of use thereof

#55
20180371440
2018-12-27

CONSTRUCTS FOR EXPRESSING LYSOSOMAL POLYPEPTIDES

#56
20180327798
2018-11-15

Method for producing steviol and steviol glycoside using AOBGL1 homolog

#57
20180318451
2018-11-08

PSMA-specific binding proteins

#58
20180298078
2018-10-18

Method for producing fusion protein having IgG Fc domain

#59
20180282381
2018-10-04

Compositions and methods for producing high secreted yields of recombinant proteins

#60
20180244762
2018-08-30

Dual PDGF/VEGF antagonists

#61
20180179263
2018-06-28

Materials and methods for producing endostatin fusion polypeptides in plant cells

#62
20180104358
2018-04-19

Modified UBE3A gene for a gene therapy approach for angelman syndrome

#63
20180051280
2018-02-22

Materials and methods for the synthesis of error-minimized nucleic acid molecules

#64
20180037613
2018-02-08

Peptides and uses thereof

#65
20180009851
2018-01-11

Compositions and methods for peptide expression and purification using a type III secretion system

#66
20170335298
2017-11-23

Multi-domain enzymes having cutinase activity, compositions comprising same and uses thereof

#67
20170333486
2017-11-23

Bioengineered adipocytes for the light-controlled release of insulin and other peptides

#68
20170268015
2017-09-21

Production of proteins in labyrinthulomycetes

#69
20170253637
2017-09-07

SIGNAL PEPTIDE FUSION PARTNERS FACILITATING LISTERIAL EXPRESSION OF ANTIGENIC SEQUENCES AND METHODS OF PREPARATION AND USE THEREOF

#70
20170174746
2017-06-22

Recombinant Bacterium and Uses Thereof

#71
20170073664
2017-03-16

Preparation of libraries of protein variants expressed in eukaryotic cells and use for selecting binding molecules

#72
20170058018
2017-03-02

Process for preparation of secretory IgA and secretory IgM

#73
20160257720
2016-09-08

HIV-1 antigens with discrete conformational forms in the V1/V2 domain and methods of use thereof

#74
20160138066
2016-05-19

Methods for the expression of peptides and proteins

#75
20150376271
2015-12-31

Dual PDGF/VEGF antagonists

#76
20150239939
2015-08-27

Composition for preventing or treating cervical cancer having human papillomavirus plasmodium and immunity enhancer

#77
20150225466
2015-08-13

Compositions and methods for peptide expression and purification using a type III secretion system

#78
20150166679
2015-06-18

Secretory immunoglobulin complex

#79
20150152144
2015-06-04

typhi Ty21a expressing F1-V fusion protein and uses thereof

#80
20150147805
2015-05-28

Vectors, host cells, and methods of production and uses

#81
20150140028
2015-05-21

Recombinant bacterium and uses thereof

#82
20150093495
2015-04-02

Nucleic Acids, Cells, and Methods for Producing Secreted Proteins

#83
20150056180
2015-02-26

Compositions comprising secretory-like immunoglobulins

#84
20150023932
2015-01-22

ENGINEERED PEPTIDE (EP)-DIRECTED PROTEIN INTERCELLULAR DELIVERY SYSTEM AND USES THEREOF

#85
20150004700
2015-01-01

Rationally designed antibodies

#86
20140349344
2014-11-27

Compositions and methods for purifying Bax

#87
20140343251
2014-11-20

Agents and methods for the expression and secretion of peptides and proteins

#88
20140342387
2014-11-20

Enzymes for degrading organophosphates

#89
20140336367
2014-11-13

Recombinant NEL-like (NELL) protein production

#90
20140335097
2014-11-13

Expression vectors for cell-surface expression of polypeptides comprising a transmembrane domain of glycophorin A

#91
20140186387
2014-07-03

Signal peptide fusion partners facilitating listerial expression of antigenic sequences and methods of preparation and use thereof

#92
20140141506
2014-05-22

Vectors, host cells, and methods of production and uses

#93
20140093929
2014-04-03

Fatty alcohol forming acyl reductases (FARs) and methods of use thereof

#94
20140051093
2014-02-20

High level expression of recombinant toxin proteins

#95
20140045216
2014-02-13

Signal sequences to improve protein expressions and secretion of recombinant enzymes and other proteins

#96
20130336946
2013-12-19

Fusion proteins and methods for treating HIV infection and AIDS related symptoms

#97
20130225451
2013-08-29

Materials and methods for the synthesis of error-minimized nucleic acid molecules

#98
20130195905
2013-08-01

Composition for preventing or treating cervical cancer having human papillomavirus plasmodium and immunity enhancer

#99
20130164254
2013-06-27

Anticancer fusion protein comprising trail

#100
20130045888
2013-02-21

Multi-copy strategy for high-titer and high-purity production of multi-subunit proteins such as antibodies in transformed microbes such as

#101
20130018177
2013-01-17

Production of sialylated -glycans in lower eukaryotes

#102
20120302512
2012-11-29

Isolated laminin-421

#103
20120288931
2012-11-15

Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA

#104
20120276072
2012-11-01

Constructs for expressing lysosomal polypeptides

#105
20120258465
2012-10-11

Mutant apoprotein of photoprotein with low calcium sensitivity

#106
20120238727
2012-09-20

DECORIN COMPOSITIONS AND USE THEREOF

#107
20120135498
2012-05-31

Method for producing serratia marcescens nuclease using a bacillus expression host

#108
20120070875
2012-03-22

Amino acid sequences which enhance peptide conjugate solubility

#109
20120028911
2012-02-02

Mucin derived polypeptides

#110
20120009640
2012-01-12

Fatty alcohol forming acyl reductases (FARs) and methods of use thereof

#111
20110287443
2011-11-24

High level expression of recombinant toxin proteins

#112
20110287037
2011-11-24

Microorganisms as carriers of nucleotide sequences coding for antigens and protein toxins, process of manufacturing and uses thereof

#113
20110263835
2011-10-27

RECOMBINANT NELL PROTEIN PRODUCTION

#114
20110206616
2011-08-25

Recombinant derivatives of botulinum neurotoxins engineered for trafficking studies and neuronal delivery

#115
20110200524
2011-08-18

VECTOR FOR USE IN MEDICINE

#116
20110154514
2011-06-23

Polynucleotide used for releasing recombinant protein to the outside of eukaryotic cell

#117
20110126304
2011-05-26

METHOD FOR DISTINGUISHING SECRETORY GRANULES OF DIFFERENT AGES

#118
20110124046
2011-05-26

Extracellular secretion of recombinant proteins

#119
20110086059
2011-04-14

Non-hemolytic ClyA for excretion of proteins

#120
20110027831
2011-02-03

PRODUCTION OF SIALYLATED N-GLYCANS IN LOWER EUKARYOTES

#121
20110027830
2011-02-03

Use of an aspartic protease (NS24) signal sequence for heterologous protein expression

#122
20110020868
2011-01-27

BACTERIAL LEADER SEQUENCES FOR INCREASED EXPRESSION

#123
20110008321
2011-01-13

Vectors, host cells, and methods of production and uses

#124
20100305002
2010-12-02

Reagents and Methods for Producing Bioactive Secreted Peptides

#125
20100299787
2010-11-25

N-terminal XA27 signal anchor and its use for localization of fusion proteins

#126
20100297729
2010-11-25

Process for producing transglutaminase

#127
20100279356
2010-11-04

Production of sialylated -glycans in lower eukaryotes

#128
20100240097
2010-09-23

Mammalian expression vector with a highly efficient secretory signal sequence

#129
20100120124
2010-05-13

Systems, methods and microrganisms for antibody production with type III secretion system

#130
20100048864
2010-02-25

Bacterial leader sequences for increased expression

#131
20100041012
2010-02-18

Rationally designed antibodies

#132
20100021997
2010-01-28

Biologically active recombinant human saposin C and PSAP

#133
20100015108
2010-01-21

Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA

#134
20090324651
2009-12-31

Methods for stimulating an immune response using bacterial antigen delivery system

#135
20090298126
2009-12-03

Methods of increasing secretion of polypeptides having biological activity

#136
20090264349
2009-10-22

CD30 Ligand

#137
20090263898
2009-10-22

Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes

#138
20090208461
2009-08-20

RECOMBINANT BACTERIA WITH E.COLI HEMOLYSIN SECRETION SYSTEM AND INCREASED EXPRESSION AND/OR SECRETION OF HLYA, PROCESS OF MANUFACTURING AND USES THEREOF

#139
20090018099
2009-01-15

PROTEIN PRODUCTION

#140
20080300207
2008-12-04

Protein production

#141
20080227154
2008-09-18

Protein Expression

#142
20080193974
2008-08-14

Bacterial leader sequences for increased expression

#143
20080187520
2008-08-07

Tool for the transfer and production of proteins using the pseudomonas type III secretion system

#144
20080181895
2008-07-31

SP16 protein

#145
20080090778
2008-04-17

Telomerase reverse transcriptase fusion protein, nucleotides encoding it, and uses thereof

#146
20070061920
2007-03-15

Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes

#147
20070026462
2007-02-01

GAS1 universal leader

#148
20060286637
2006-12-21

Production of sialylated -glycans in lower eukaryotes

#149
20060246539
2006-11-02

Protein production method utilizing yebF

#150
20060239966
2006-10-26

In vivo gene therapy of parkinson's disease

#151
20060179493
2006-08-10

Transgenically produced non-secreted proteins

#152
20060150271
2006-07-06

Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes

#153
20060095988
2006-05-04

Synthetic plant genes and method for preparation

#154
20060095984
2006-05-04

Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes

#155
20060068469
2006-03-30

Bacterial vector systems

#156
20060057130
2006-03-16

Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA

#157
20060008877
2006-01-12

Expression systems with sec-system secretion

#158
20050288220
2005-12-29

Erythropoietin with high specific activity

#159
20050227357
2005-10-13

Recombinant Penicillium funiculosum for homologous and heterologous protein production

#160
20050153909
2005-07-14

Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes

#161
20050090007
2005-04-28

Identification of human cell lines for the production of human proteins by endogenous gene activation