97364 ⎘
Fusion polypeptide containing a motif/fusion for degradation (ubiquitin fusions, PEST sequence)
MALTOSE DEPENDENT DEGRONS, MALTOSE-RESPONSIVE PROMOTERS, STABILIZATION CONSTRUCTS, AND THEIR USE IN PRODUCTION OF NON-CATABOLIC COMPOUNDS
#2MULTIEPITOPE UNIVERSAL INFLUENZA VACCINE
#3Polyamine Reporters
#4TREATMENT OF NERVOUS SYSTEM INJURY AND NEURODEGENERATIVE DISORDERS AND RELATED CONDITIONS
#5ANTI-SOD1 NANOBODIES
#6A TRUNCATED PROTEIN AND USE THEREOF
#7TRANSPOSASE FUSION PROTEINS FOR USE IN CELL AND GENE THERAPY
#8BACTERIOCIN POLYPEPTIDES, NUCLEIC ACIDS ENCODING SAME, AND METHODS OF USE THEREOF
#9TARGETED PROTEIN DEGRADATION SYSTEM AND USE THEREOF
#10COMPOSITIONS AND METHODS FOR CONTROLLED PROTEIN DEGRADATION IN NEURODEGENERATIVE DISEASE
#11METHOD FOR ROBUST CONTROL OF GENE EXPRESSION
#12IMMUNE CELLS EXPRESSING A HYPOXIA-DEPENDENT CHIMERIC ANTIGEN RECEPTOR TARGETED TO EGFR
#13Multifunctional Multispecific Multimeric Biomolecule Polymer Having Prolonged In-Vivo Duration
#14ZINC FINGER DEGRON SEQUENCES
#15COMPOSITIONS COMPRISING MODIFIED FLAVIVIRUS E GLYCOPROTEINS AND METHODS OF MAKING AND USING THE SAME
#16METHODS AND COMPOSITIONS FOR CONTROLLING T CELL ACTIVATION
#17FUSION PROTEIN FOR TARGETING RECOMBINANT PROTEINS FOR DEGRADATION
#18AUXIN-DEGRON SYSTEM KIT AND USE THEREFOR
#19METHODS AND COMPOSITIONS FOR DETERMINING THE ANTIGEN SPECIFICITY OF T CELLS
#20ENGINEERED MCP AND PCP PROTEINS AND SYSTEMS AND METHODS THEREOF
#21TARGETED DEGRADATION OF ALPHA-SYNUCLEIN
#22REGULATED SYNTHETIC GENE ACTIVATION SYSTEMS
#23BACTERIAL SYSTEMS FOR ANALYZING UBIQUITYLATED POLYPEPTIDES
#24NUCLEIC ACID MOLECULES, FUSION PROTEINS, AND MRNA VACCINES WITH ENHANCED ANTIGEN PRESENTATION BY RECRUITING LIGANDS
#25METHODS AND USES FOR NDFIP1 FUSION POLYPEPTIDES IN TREATING NEURODEGENERATIVE DISEASES, BRAIN AND/OR TRAUMATIC AND NON-TRAUMATIC SPINAL CORD INJURIES, AND/OR OPTIC NEUROPATHIES
#26COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION
#27RECOMBINANT VIRUS CONTAINING DEGRON, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
#28BIO PROTAC PROTEIN HAVING INTRACELLULAR DELIVERY FUNCTION, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
#29CRISPR/CAS SYSTEM AND METHOD FOR GENOME EDITING AND MODULATING TRANSCRIPTION
#30CONDITIONAL DEGRADATION OF PROTEINS THAT ARE LOCALIZED AT THE PLASMA MEMBRANE
#31MODIFICATION OF RNA-RELATED ENZYMES FOR ENHANCED PRODUCTION
#32Method for robust control of gene expression
#33CONDITIONAL DEGRADATION OF PROTEINS THAT ARE LOCALIZED AT THE PLASMA MEMBRANE
#34IMMUNOGENIC COMPOSITIONS TARGETING RECURRENT CANCER MUTATIONS AND METHODS OF USE THEREOF
#35METHODS OF REGULATING ADENO-ASSOCIATED VIRUS PRODUCTION
#36SECRETABLE PAYLOAD REGULATION
#37WW-DOMAIN-ACTIVATED EXTRACELLULAR VESICLES TARGETING CORONAVIRUSES
#38TREATMENT OF NERVOUS SYSTEM INJURY AND NEURODEGENERATIVE DISORDERS AND RELATED CONDITIONS
#39PROTEIN TAG TO INDUCE LIGAND DEPENDENT DEGRADATION OF PROTEIN/PROTEIN-FUSIONS
#40BETA-ARRESTIN COMPOSITIONS AND ASSOCIATED METHODS
#41RECOMBINANT VECTOR OF THERMOLABILE UNG FUSED PROTEIN AND AN EXPRESSING AND PURIFYING METHOD
#42CHIMERIC POLYPEPTIDES
#43ZINC FINGER DEGRADATION DOMAINS
#44Composition and Methods for Selective Degradation of Engineered Proteins
#45COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN EXPRESSION
#46PROTEIN TAG TO INDUCE LIGAND DEPENDENT DEGRADATION OF PROTEIN/PROTEIN-FUSIONS
#47AUXIN-INDUCIBLE DEGRON SYSTEM KIT AND USE THEREOF
#48NONHUMAN ANIMAL AND USE FOR SAME
#49Methods and compositions for reducing the immunogenicity of chimeric notch receptors
#50METHODS AND COMPOSITIONS FOR REDUCING THE IMMUNOGENICITY OF CHIMERIC NOTCH RECEPTORS
#51METHODS AND COMPOSITIONS FOR THE POSITIVE SELECTION OF PROTEIN DESTABILIZERS
#52TARGETED PROTEIN SILENCING USING CHIMERAS BETWEEN ANTIBODIES AND UBIQUITINATION ENZYMES
#53SELECTIVE DEGRADATION OF PROTEINS
#54COMPOSITIONS FOR REGULATING AND SELF-INACTIVATING ENZYME EXPRESSION AND METHODS FOR MODULATING OFF-TARGET ACTIVITY OF ENZYMES
#55CHEMICALLY INDUCIBLE POLYPEPTIDE POLYMERIZATION
#56COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION
#57ANTI-RHO GTPASE CONFORMATIONAL SINGLE DOMAIN ANTIBODIES AND USES THEREOF
#58Tagged chimeric effector molecules and receptors thereof
#59TUNABLE ENDOGENOUS PROTEIN DEGRADATION
#60CAGED-DEGRON-BASED MOLECULAR FEEDBACK CIRCUITS AND METHODS OF USING THE SAME
#61Enhanced hAT family transposon-mediated gene transfer and associated compositions, systems, and methods
#62PEPTIDE TAGS FOR LIGAND INDUCED DEGRADATION OF FUSION PROTEINS
#63PEPTIDE DIRECTED PROTEIN KNOCKDOWN
#64POLYNUCLEOTIDE AND USES THEREOF
#65MODIFICATION OF RNA-RELATED ENZYMES FOR ENHANCED PRODUCTION
#66Bi-functional anti-tau polypeptides and use thereof
#67ANTI-TAU CONSTRUCTS
#68ANTI-CD33 AND NKG2D LIGAND CHIMERAS FOR TREATMENT OF MYELOID MALIGNANCIES
#69LINEAR POLYFUNCTIONAL MULTIMER BIOMOLECULE COUPLED TO POLYUBIQUITIN LINKER AND USE THEREOF
#70CYTOTOXIC MOLECULES RESPONSIVE TO INTRACELLULAR LIGANDS FOR SELECTIVE T CELL MEDIATED KILLING
#71DEGRADATION DOMAIN MODIFICATIONS FOR SPATIO-TEMPORAL CONTROL OF RNA-GUIDED NUCLEASES
#72TARGETED PROTEIN DEGRADATION TO ATTENUATE ADOPTIVE T-CELL THERAPY ASSOCIATED ADVERSE INFLAMMATORY RESPONSES
#73BACTERIAL SYSTEMS FOR ANALYZING UBIQUITYLATED POLYPEPTIDES
#74MODIFIED MITOCHONDRIA AND USE THEREOF
#75MALTOSE DEPENDENT DEGRONS, MALTOSE-RESPONSIVE PROMOTERS, STABILIZATION CONSTRUCTS, AND THEIR USE IN PRODUCTION OF NON-CATABOLIC COMPOUNDS
#76Anti-rho GTPase conformational single domain antibodies and uses thereof
#77Method for robust control of gene expression
#78Methods of treating spinal cord injury using a chondroitin sulfate proteoglycan (CSPG) reduction peptide (CRP) comprising a cell membrane penetrating domain, a CSPG binding domain, and a lysosome targeting domain
#79Self-inactivating rabies virus vector encoding a nucleoprotein and degron
#80PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF
#81BROAD-SPECTRUM PROTEOME EDITING WITH AN ENGINEERED BACTERIAL UBIQUITIN LIGASE MIMIC
#82Compositions and methods for inducing conformational changes in cereblon and other E3 ubiquitin ligases
#83MALTOSE DEPENDENT DEGRONS, MALTOSE-RESPONSIVE PROMOTERS, STABILIZATION CONSTRUCTS, AND THEIR USE IN PRODUCTION OF NON-CATABOLIC COMPOUNDS
#84Enhanced hAT family transposon-mediated gene transfer and associated compositions, systems, and methods
#85Compositions and methods for selective protein degradation
#86Chimeric proteins and their use in identifying anti-deubiquitinase compounds
#87CRISPR/Cas system and method for genome editing and modulating transcription
#88Targeted protein degradation
#89Tagged chimeric effector molecules and receptors thereof
#90DEGRON FUSION CONSTRUCTS AND METHODS FOR CONTROLLING PROTEIN PRODUCTION
#91Methods of treating spinal cord injury using a chondroitin sulfate proteoglycan (CSPG) reduction peptide (CRP) comprising a cell membrane penetrating domain, a CSPG binding domain, and a lysosome targeting domain
#92Tunable endogenous protein degradation with heterobifunctional compounds
#93Method for expressing and purifying soluble protein of CRM197
#94Immunogenic compositions targeting recurrent cancer mutations and methods of use thereof
#95Peptide directed protein knockdown
#96Chromatography resin, production and use thereof
#97Methods and compositions for the positive selection of protein destabilizers
#98Targeted protein silencing using chimeras between antibodies and ubiquitination enzymes
#99Bi-functional anti-tau polypeptides and use thereof
#100Bacterial systems for analyzing ubiquitylated polypeptides
#101Modification of RNA-related enzymes for enhanced production
#102Immunomodulating composition for treatment
#103Method for producing TLR5 agonist protein
#104Chimeric proteins and their use in identifying anti-deubiquitinase compounds
#105Methods of identifying a polypeptide target for degradation by a modulator of CRBN
#106Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases
#107Compositions and methods for inducing conformational changes in cereblon and other E3 ubiquitin ligases
#108Targeted protein degradation
#109Methods and compositions for reducing the immunogenicity of chimeric notch receptors
#110Small-molecule hydrophobic tagging of fusion proteins and induced degradation of same
#111Enhanced hAT family transposon-mediated gene transfer and associated compositions, systems, and methods
#112Ubiquitin interacting motif peptides as therapeutics
#113Probes and assays for measuring E3 ligase activity
#114Enhanced hAT Family Transposon-Mediated Gene Transfer and Associated Compositions, Systems, and Methods
#115Enhanced hAT family transposon-mediated gene transfer and associated compositions, systems and methods
#116Maltose dependent degrons, maltose-responsive promoters, stabilization constructs, and their use in production of non-catabolic compounds
#117Fluorescence amplification method for forward genetic discovery of factors in human mRNA degradation
#118Tunable endogenous protein degradation
#119Degron fusion constructs and methods for controlling protein production
#120Maltose dependent degrons, maltose-responsive promoters, stabilization constructs, and their use in production of non-catabolic compounds
#121Targeted protein degradation to attenuate adoptive T-cell therapy associated adverse inflammatory responses
#122Protein degradation inducing tag and usage thereof
#123Combination Therapies With Recombinant Listeria Strains
#124METHOD FOR ANTIGEN LOADING OF DENDRITIC CELLS AND VACCINE
#125EGFR binding proteins
#126ANTI-TAU CONSTRUCTS
#127Cytotoxic molecules responsive to intracellular ligands for selective T cell mediated killing
#128Sequence arrangements and sequences for neoepitope presentation
#129Small-Molecule Hydrophobic Tagging of Fusion Proteins and Induced Degradation of Same
#130Tagged chimeric effector molecules and receptors thereof
#131THERAPEUTIC COMPOSITIOJNS AND METHODS FOR INDUCING AN IMMUNE RESPONSE TO HERPES SIMPLEX VIRUS TYPE 2 (HSV-2)
#132Modification of RNA-related enzymes for enhanced production
#133Genetically encoded histone reporter allele constructs
#134Biomarker directed multi-target immunotherapy
#135Neurotoxins exhibiting shortened biological activity
#136Antimicrobial agents
#137Degradation of Beta-Amyloid Proteins With Keratinase
#138Modified plant defensins useful as anti-pathogenic agents
#139CRISPR-Mediated Genome Engineering for Protein Depletion
#140FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME
#141Method of generating linkage-specific di-and polyprotein probes
#142Parkin ligase activation methods and compositions
#143Immune modulation
#144Neurotoxins exhibiting shortened biological activity
#145Tunable control of protein degradation in synthetic and endogenous bacterial systems
#146Peptide directed protein knockdown
#147Chimeric dystrophin-VSV-G protein to treat dystrophinopathies
#148Inhibitors of the Epidermal Growth Factor Receptor- Heat Shock Protein 90 Binding Interaction
#149Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases
#150Matrix metalloproteinase cleavable protein polymers for cancer gene therapy
#151Fermented infant formula with non digestible oligosaccharides
#152Methyl degron peptide and methods of controlling protein lifespan
#153FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME
#154Catalytic Tagging System to Study Macro-Molecular Interactions Using Engineered Ubiquitin Ligase and Ubiquitin-Like Proteins to Facilitate Substrate Identification
#155TREATMENT OF HYPOGLYCEMIA
#156Small-molecule hydrophobic tagging of fusion proteins and induced degradation of same
#157Modified plant defensins useful as anti-pathogenic agents
#158Dimeric binding proteins based on modified ubiquitins
#159Method for producing web protein, a fused protein, recombinant DNA, an expression vector, a host cell and strain-producers
#160Cross-linked peptides and proteins, methods of making same, and uses thereof
#161Neurotoxins exhibiting shortened biological activity
#162Well-defined oligomers of ubiquitin and ubiquitin-like polypeptides, and methods for preparing same
#163Protein complex and method of preparing same
#164Method for identifying hetero-multimeric modified ubiquitin proteins with binding capability to ligands
#165Engineered E2 for increasing the content of free LYS11-linked ubiquitin
#166Factor VIII Compositions and Methods of Making and Using Same
#167Modified ubiquitin proteins having a specific binding activity for the extradomain B of fibronectin
#168MODIFIED UBIQUITIN PROTEINS HAVING A SPECIFIC BINDING ACTIVITY FOR THE EXTRADOMAIN B OF FIBRONECTIN
#169Inhibitors of the epidermal growth factor receptor-heat shock protein 90 binding interaction
#170FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME
#171MEANS AND METHODS FOR COUNTERACTING POLYQ EXPANSION DISORDERS
#172Neurotoxins exhibiting shortened biological activity
#173Methods and molecules for yield improvement involving metabolic engineering
#174Expression system for modulating an immune response
#175Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases
#176FUSION PROTEIN COMPRISING UBIQUITIN OR UBIQUITIN-LIKE PROTEIN, MEMBRANE TRANSLOCATION SEQUENCE AND BIOLOGICALLY ACTIVE MOLECULE AND USE THEREOF
#177DNA immunization protocols
#178Designer Ubiquitin Ligases For Regulation Of Intracellular Pathogenic Proteins
#179Method of producing virus-like particles of picornavirus using a small-ubiquitin-related fusion protein expression system
#180Method for transcription/degradation dual control of protein by antibiotic
#181Trimerising module
#182Trimerising module
#183Two-component genome flavivirus and uses thereof
#184Rapidly cleavable sumo fusion protein expression system for difficult to express proteins
#185Compositions comprising HMW-MAA and fragments thereof, and methods of use thereof
#186Compositions comprising HMW-MAA and fragments thereof, and methods of use thereof
#187DNA-BASED VACCINATION OF RETROVIRAL-INFECTED INDIVIDUALS UNDERGOING TREATMENT
#188Pharmaceutical compositions and methods for delivering nucleic acids into cells
#189Methods and Compositions for Protein Expression and Purification
#190Nucleic acids encoding chimeric interleukin-6 soluble receptor/ligand protein, analogs thereof and uses thereof
#191Trimerising module
#192Method for the production of amyloid-beta peptide using ubiquitin
#193Methods and compositions for protein expression and purification
#194Enhanced secretion of a polypeptide by a microorganism
#195Conditional allele system
#196Enhanced secretion of a polypeptide by a microorganism
#197Enhanced secretion of a polypeptide by a microorganism
#198Rapidly degrading GFP-fusion proteins and methods of use
#199Enhanced secretion of a polypeptide by a microorganism
#200Targeted polypeptide degradation
#201Enhanced secretion of a polypeptide by a microorganism
#202Therapeutic and diagnostic methods and compositions based on notch proteins and nucleic acids
#203Rapidly cleavable SUMO fusion protein expression system for difficult to express proteins
#204Selective degradation of proteins