109032 ⎘
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor; Recombinant DNA-technology; Processes for the isolation, preparation or purification of DNA or RNA; Isolating an individual clone by screening libraries Gene trapping, e.g. exon-, intron-, IRES-, signal sequence-trap cloning, trap vectors
Blockers, Kits and Methods of Use Thereof
#2METHODS FOR HIGH-RESOLUTION GENOME-WIDE FUNCTIONAL DISSECTION OF TRANSCRIPTIONAL REGULATORY REGIONS
#3COMPOSITIONS AND METHODS FOR THE TARGETING OF SOD1
#4GENERATING MAMMALIAN T CELL ACTIVATION INDUCIBLE SYNTHETIC PROMOTERS (SYN+PRO) TO IMPROVE T CELL THERAPY
#5SYNTHETIC INTRONS FOR TARGETED GENE EXPRESSION
#6COMPOSITIONS AND METHODS FOR MAMMALIAN GENETICS AND USES THEREOF
#7KRAB FUSION REPRESSORS AND METHODS AND COMPOSITIONS FOR REPRESSING GENE EXPRESSION
#8Compositions and methods for identifying polynucleotides of interest
#9Method for Preparing Combinatorial Library of Multi-Modular Biosynthetic Enzyme Gene
#10HIGH-THROUGHPUT SCREENING PLATFORM FOR ENGINEERING NEXT-GENERATION GENE THERAPY VECTORS
#11RAPID CHARACTERIZATION OF CAS ENDONUCLEASE SYSTEMS, PAM SEQUENCES AND GUIDE RNA ELEMENTS
#12COMPOSITIONS AND METHODS FOR THE TARGETING OF SOD1
#13Compositions and methods for the targeting of SOD1
#14Preparation of Combinatorial Libraries of DNA Constructs
#15Transcription Factor Trapping by RNA in Gene Regulatory Elements
#16Methods for high-resolution genome-wide functional dissection of transcriptional regulatory regions
#17Compositions and methods for identifying polynucleotides of interest
#18Generating mammalian T cell activation inducible synthetic promoters (SYN+PRO) to improve T cell therapy
#19Compositions and methods for mammalian genetics and uses thereof
#20ASSAYS TO IDENTIFY GENETIC ELEMENTS AFFECTING PHENOTYPE
#21Modified FRT recombination site libraries and methods of use
#22Compositions and methods that are useful for identifying allele variants that modulate gene expression
#23Methods of designing programmable inducible promoters
#24Rapid characterization of Cas endonuclease systems, PAM sequences and guide RNA elements
#25Assays to identify genetic elements affecting phenotype
#26Compositions and methods for identifying polynucleotides of interest
#27Modified FRT Recombination Site Libraries and Methods of Use
#28Mutated internal ribosomal entry site (IRES) for controlled gene expression
#29Phage displaying system expressing single chain antibody
#30Modified FRT recombination site libraries and methods of use
#31Translational enhancer-element dependent vector systems
#32Bidirectional promoter
#33Phage displaying system expressing single chain antibody
#34Method for isolation of transcription termination sequences
#35FRT recombination sites and methods of use
#36VECTORS AND METHODS FOR SELECTING OPEN READING FRAMES
#37METHODS FOR IDENTIFYING MARKERS FOR EARLY-STAGE HUMAN CANCER, CANCER PROGRESSION AND RECURRENCE
#38Compositions and Methods for the Regulation of Multiple Genes of Interest in a Cell
#39TUMOR-SPECIFIC BACTERIAL PROMOTER ELEMENTS
#40RATIONAL LIBRARY
#41COMPOSITIONS AND METHODS FOR MAMMALIAN GENETICS AND USES THEREOF
#42METHOD OF PRODUCING HUMAN IGG ANTIBODIES WITH ENHANCED EFFECTOR FUNCTIONS
#43Screening method and vector, vector library, and assay kit used therefor
#44Translation enhancer-element dependent vector systems
#45Trap vectors and gene trapping method by using the same
#46Method for performing genetic modification under a drug-free environment and components thereof
#47METHODS FOR IDENTIFYING NOVEL NUCLEIC ACID REGULATORY ELEMENTS AND COMPOUNDS THAT AFFECT THE REGULATION
#48PHAGE DISPLAYING SYSTEM EXPRESSING SINGLE CHAIN ANTIBODY
#49PROMOTER DETECTION AND ANALYSIS
#50FRT recombination sites and methods of use
#51SCREENING METHODS FOR IDENTIFYING TARGET ANTIFUNGAL GENES AND COMPOUNDS BY DETECTING CELL SURFACE GLYCOPROTEINS
#52Enhancer-containing gene trap vectors for random and targeted gene trapping
#53FRT recombination sites and methods of use
#54In vivo genome-wide mutagenesis
#55Modified FRT recombination site libraries and methods of use
#56Screening of abundantly secreted proteins and their use as fusion partners for the production of recombinant proteins
#57NOVEL METHODS
#58Vectors for Inducing Homozygous Mutations and Methods of Using Same
#59METHODS FOR SELECTIVELY CAPTURING AND AMPLIFYING EXONS OR TARGETED GENOMIC REGIONS FROM BIOLOGICAL SAMPLES
#60Compositions and methods related to mRNA translational enhancer elements
#61Method of Producing Human IgG Antibodies with Enhanced Effector Functions
#62Trap vectors and gene trapping using the same
#63Indexed library of cells containing genomic modifications and methods of making and utilizing the same
#64GENE TRAP CASSETTES FOR RANDOM AND TARGETED CONDITIONAL GENE INACTIVATION
#65Promoter Detection and Analysis
#66Methods of Identifying Synthetic Transcriptional and Translational Regulatory Elements, and Compositions Related to Same
#67MAMMALIAN GENES INVOLVED IN VIRAL INFECTION AND TUMOR SUPPRESSION
#68TRANSLATION INITIATION REGION SEQUENCES FOR OPTIMAL EXPRESSION OF HETEROLOGOUS PROTEINS
#69Transcriptional regulatory elements of biological pathways tools, and methods
#70Functional Genomics and Gene Trapping in Haploid or Hypodiploid Cells
#71Methods For Gene Targeting
#72FRT recombination sites and methods of use
#73Methods of identifying synthetic transcriptional and translational regulatory elements, and compositions relating to same
#74Method for isolation of transcription termination sequences
#75Methods for identifying markers for early-stage human cancer, cancer progression and recurrence
#76Methods for identifying novel nucleic acid regulatory elements and compounds that affect the regulation
#77Method of screening for protein secretion recombinant host cells
#78Vector system for selection of genes encoding secreted proteins and membrane-bound proteins
#79Translation enhancer-element dependent vector systems
#80Modified FRT recombination site libraries and methods of use
#81Methods of isolating genes encoding proteins of specific function and of screening for pharmaceutically active agents
#82Isolating cells expressing secreted proteins
#83Methods to identify plant metabolites
#84SYSTEM FOR PRODUCING SYNTHETIC PROMOTERS
#85Tagged epitope protein transposable element
#86Nucleic acid sequences having an activity of regulating translation efficiency and utilization thereof
#87Methods for rolling circle amplification and signal trapping of libraries
#88Mammalian genes involved in viral infection and tumor suppression
#89System for producing synthetic promoters
#90Isolating cells expressing secreted proteins
#91Methods for screening for proteins comprising a signal sequence
#92Method for the identification of tissue-specific regulatory sequences
#93Method for identifying genes encoding signal sequences
#94Synthetic cell-or tissue-specific transcriptional regulatory regions
#95Method for evolving a cell having desired phenotype and evolved cells
#96Screening method
#97Vectors for gene mutagenesis and gene discovery
#98Vectors for making genomic modifications
#99Novel human polynucleotides and the polypeptides encoded thereby
#100Compositions for isolating a cDNA encoding a membrane-bound protein
#101Identification of eukaryotic internal ribosome entry site (IRES) elements