109040 ⎘
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor; Recombinant DNA-technology; Processes for the isolation, preparation or purification of DNA or RNA; Isolating an individual clone by screening libraries Screening libraries by altering the phenotype or phenotypic trait of the host
Methods and Kits for Identifying Cancer Treatment Targets
#2FolA Selection Assay to Identify Strains with Increased Soluble Target Protein Expression
#3OPTIMIZED NUCLEIC ACID ANTIBODY CONSTRUCTS
#4NOVEL TYPE I-B CRISPR-CAS SYSTEM FROM CLOSTRIDIA
#5A METHOD FOR IDENTIFYING PEPTIDE THERAPEUTICS TO TREAT A VARIETY OF CONDITIONS
#6PROTEIN EXPRESSION
#7Methods and kits for identifying cancer treatment targets
#8MULTIPLEX GENOME ENGINEERING IN EUKARYOTES
#9METHODS AND SYSTEMS FOR CRISPR SELECTION
#10FUNCTIONAL GENOMICS USING CRISPR-CAS SYSTEMS FOR SATURATING MUTAGENESIS OF NON-CODING ELEMENTS, COMPOSITIONS, METHODS, LIBRARIES AND APPLICATIONS THEREOF
#11OLIGONUCLEIC ACID VARIANT LIBRARIES AND SYNTHESIS THEREOF
#12METHODS AND COMPOSITIONS FOR MUTAGENESIS SCREENING IN MAMMALIAN CELLS
#13COMPOSITIONS AND METHODS FOR IN VIVO SCREENING OF THERAPEUTICS USING SINGLE NUCLEUS SEQUENCING
#14METHODS OF IDENTIFYING A CONDENSATE PHENOTYPE AND USES THEREOF
#15FUNCTIONAL GENOMICS USING CRISPR-CAS SYSTEMS FOR SATURATING MUTAGENESIS OF NON-CODING ELEMENTS, COMPOSITIONS, METHODS, LIBRARIES AND APPLICATIONS THEREOF
#16CRISPR/CAS DROPOUT SCREENING PLATFORM TO REVEAL GENETIC VULNERABILITIES ASSOCIATED WITH TAU AGGREGATION
#17HIGH-THROUGHPUT PRECISION GENOME EDITING
#18COMPOSITIONS AND METHODS FOR MAMMALIAN GENETICS AND USES THEREOF
#19PRODUCTION OF ANTIGEN-SPECIFIC T-CELLS
#20COMPOSITIONS AND METHODS FOR ENGINEERING AND SELECTION OF CAR T CELLS WITH DESIRED PHENOTYPES
#21A HTP PLATFORM FOR THE GENETIC ENGINEERING OF CHINESE HAMSTER OVARY CELLS
#22METHODS FOR GENERATING BARCODED COMBINATORIAL LIBRARIES
#23MODULAR POLYPEPTIDE LIBRARIES AND METHODS OF MAKING AND USING SAME
#24COMPOSITIONS AND METHODS OF TREATING GLIOMA
#25SECONDARY METABOLITE SCREENING SYSTEM
#26METHODS FOR IDENTIFYING A CELL UPTAKE MECHANISM
#27METHODS AND COMPOSITIONS FOR STUDYING CELL EVOLUTION
#28CRISPR/CAS TRANSCRIPTIONAL MODULATION
#29GENE FRAGMENT OVEREXPRESSION SCREENING METHODOLOGIES, AND USES THEREOF
#30HTP GENOMIC ENGINEERING PLATFORM
#31Novel Xanthomonas Strains and Related Methods
#32Methods and kits for identifying cancer treatment targets
#33Methods for Screening Bacteria, Archaea, Algae, and Yeast Using CRISPR Nucleic Acids
#34METHOD FOR IDENTIFYING FUNCTIONAL ELEMENTS
#35HTP GENOMIC ENGINEERING PLATFORM FOR IMPROVING FUNGAL STRAINS
#36PROGRAMMABLE ARRAYS
#37COMPOSITIONS AND METHODS FOR HIGHLY EFFICIENT GENETIC SCREENING USING BARCODED GUIDE RNA CONSTRUCTS
#38COMPOSITIONS AND METHODS FOR IN VIVO SCREENING OF THERAPEUTICS
#39MODIFIED MEMBRANE SPANNING PROTEINS AND METHODS FOR THE PREPARATION AND USE THEREOF
#40Methods and kits for identifying cancer treatment targets
#41ENCODING OF DNA VECTOR IDENTITY VIA ITERATIVE HYBRIDIZATION DETECTION OF A BARCODE TRANSCRIPT
#42HTP genomic engineering platform for improving fungal strains
#43Systems and methods for host cell improvement utilizing epistatic effects
#44HTP genomic engineering platform
#45HTP genomic engineering platform
#46HTP PLATFORM FOR THE GENETIC ENGINEERING OF CHINESE HAMSTER OVARY CELLS
#47DIRECTED CELL FATE SPECIFICATION AND TARGETED MATURATION
#48Generation of synthetic genomes
#49Systems and Methods for Identifying and Expressing Gene Clusters
#50Systems and methods for genetic manipulation of species
#51HTP genomic engineering platform
#52Multiplex genome engineering in eukaryotes
#53Multiplex Alteration of Cells Using a Pooled Nucleic Acid Library and Analysis Thereof
#54Optimized nucleic acid antibody constructs encoding anti-respiratory syncytial virus (RSV) antibodies
#55Methods and compositions for studying cell evolution
#56METHODS FOR PREPARATION OF NUCLEIC ACID SEQUENCING LIBRARIES
#57Automated system for HTP genomic engineering
#58Oligonucleic acid variant libraries and synthesis thereof
#59HTP genomic engineering platform
#60ORGANIC COMPOUNDS
#61HIGH-THROUGHPUT METHODS FOR IDENTIFYING GENE INTERACTIONS AND NETWORKS
#62HTP platform for the genetic engineering of Chinese hamster ovary cells
#63SYSTEMS, METHODS, AND COMPOSITIONS FOR TARGETED NUCLEIC ACID EDITING
#64Micro-screening Apparatus, Process, and Products
#65RNA INTERFERENCE MEDIATING SMALL RNA MOLECULES
#66CRISPR/Cas dropout screening platform to reveal genetic vulnerabilities associated with tau aggregation
#67Methods and systems for CRISPR selection
#68Automated system for HTP genomic engineering
#69PRODUCTION OF ANTIGEN-SPECIFIC T-CELLS
#70METHODS AND COMPOSITIONS FOR MASSIVELY PARALLEL VARIANT AND SMALL MOLECULE PHENOTYPING
#71RNA SEQUENCE-SPECIFIC MEDIATORS OF RNA INTERFERENCE
#72Microbial strain improvement by a HTP genomic engineering platform
#73Modular polypeptide libraries and methods of making and using same
#74Methods for Transfecting Nucleic Acid Into Live Cells
#75SYSTEMATIC SCREENING AND MAPPING OF REGULATORY ELEMENTS IN NON-CODING GENOMIC REGIONS, METHODS, COMPOSITIONS, AND APPLICATIONS THEREOF
#76HTP genomic engineering platform for improving fungal strains
#77Method of improving characteristics of proteins
#78A HIGH-THROUGHPUT (HTP) GENOMIC ENGINEERING PLATFORM FOR IMPROVING SACCHAROPOLYSPORA SPINOSA
#79HTP genomic engineering platform for improving fungal strains
#80Systems and methods for host cell improvement utilizing epistatic effects
#81Systems and Methods for Identifying and Expressing Gene Clusters
#82Anti-CRISPR genes and proteins and methods of use
#83Compositions and methods for mammalian genetics and uses thereof
#84High-throughput precision genome editing
#85Microbial strain improvement by a HTP genomic engineering platform
#86Processes and host cells for genome, pathway, and biomolecular engineering
#87ASSAYS TO IDENTIFY GENETIC ELEMENTS AFFECTING PHENOTYPE
#88BIC INHIBITOR OF CRY-CRY AND CRY-CIB OLIGOMERIZATION/CLUSTERING
#89Metabolically competent cells, methods of making, and uses thereof
#90Modified membrane spanning proteins and methods for the preparation and use thereof
#91Methods for the Characterisation of Interaction Sites on Target Proteins
#92Methods for generating barcoded combinatorial libraries
#93Methods of screening using barcoded libraries
#94Combinatorial Metabolic Engineering Using a CRISPR System
#95Compositions and methods for evaluating and modulating immune responses by detecting and targeting GATA3
#96Compositions and methods for evaluating and modulating immune responses by detecting and targeting POU2AF1
#97Markers of plant health
#98Method of improving characteristics of proteins
#99Methods for screening bacteria, archaea, algae, and yeast using CRISPR nucleic acids
#100Yeast cells expressing TAR DNA-binding protein 43 and uses therefor
#101METHODS AND COMPOSITIONS FOR CREATING ALTERED AND IMPROVED CELLS AND ORGANISMS
#102Platform for screening phosphomevalonate decarboxylase
#103Processes and host cells for genome, pathway, and biomolecular engineering
#104High-throughput screening of regulatory element function with epigenome editing technologies
#105Mammalian haploid embryonic stem cells
#106PROGRAMMABLE ARRAYS
#107TRANSCRIPTION FACTOR DECOYS
#108Antibiotic testing and screening system
#109Methods for generating barcoded combinatorial libraries
#110Methods for generating barcoded combinatorial libraries
#111Microbial strain improvement by a HTP genomic engineering platform
#112Microbial strain improvement by a HTP genomic engineering platform
#113Microbial strain improvement by a HTP genomic engineering platform
#114Assays to identify genetic elements affecting phenotype
#115Synthetic auxotrophs with ligand dependent essential genes for biosafety
#116Functional genomics using CRISPR-Cas systems for saturating mutagenesis of non-coding elements, compositions, methods, libraries and applications thereof
#117Generation of synthetic genomes
#118Encoding of DNA vector identity via iterative hybridization detection of a barcode transcript
#119Methods of identifying biologically active random peptides in plants and libraries of plants expressing candidate biologically active random peptides
#120Genome-originated artificial ncRNA expression library and method of preparing the same
#121TRANSCRIPTION FACTOR DECOYS, COMPOSITIONS AND METHODS
#122Methods for generating barcoded combinatorial libraries
#123RNA interference mediating small RNA molecules
#124Yeast cells expressing TAR DNA-binding protein 43 and uses therefor
#125Systems and methods for genetic analysis of intractable microbes
#126QTL responsible for tomato fruit firmness
#127Methods for Sequential Screening with Co-Culture Based Detection of Metagenomic Elements Conferring Heterologous Metabolite Secretion
#128CRISPR/Cas transcriptional modulation
#129Pri-mirna libraries and methods for making and using pri-mirna libraries
#130Microbial strain improvement by a HTP genomic engineering platform
#131Oligonucleic acid variant libraries and synthesis thereof
#132TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR (TALE) LIBRARIES AND METHODS OF SYNTHESIS AND USE
#133Organic compounds
#134Methods for screening bacteria, archaea, algae, and yeast using CRISPR nucleic acids
#135Clonal analysis of functional genomic assays and compositions for practicing same
#136NOVEL OLIGO-LINKER-MEDIATED DNA ASSEMBLY METHOD AND APPLICATIONS THEREOF
#137Methods and compositions for creating altered and improved cells and organisms
#138TECHNOLOGIES FOR MANUFACTURING AN ENGINEERED BIO-SYSTEM
#139Micro-screening apparatus, process, and products
#140Micro-screening apparatus, process, and products
#141Pri-mirna libraries and methods for making and using pri-mirna libraries
#142Processes and host cells for genome, pathway, and biomolecular engineering
#143Methods for cloning and manipulating genomes
#144Modified membrane spanning proteins and methods for the preparation and use thereof
#145RNA sequence-specific mediators of RNA interference
#146Method of screening cell clones
#147Method for screening mutant microorganism overproducing target metabolite using synthetic suicide genetic circuit
#148Anthocyanins with specific properties
#149Screening method for drug target gene using heterozygous deletion fission yeast strain
#150METHODS FOR IDENTIFYING PLANT PATHOGEN RESISTANCE GENES
#151RNAI BASED SELECTION SYSTEM
#152Methods for generating pools of variants of a DNA template
#153RNA interference mediating small RNA molecules
#154Massively parallel combinatorial genetics
#155Methods for the Characterisation of Interaction Sites on Target Proteins
#156QTL responsible for tomato fruit firmness
#157Method for production of isoprenoid compounds
#158Global transcription machinery engineering
#159RNAi-based method of screening and characterizing drug combinations
#160RNAi-based method of drug screening and characterization
#161Systems for induction of gene expression and protein depletion in yeast
#162Mammalian haploid embryonic stem cells
#163RNA sequence-specific mediators of RNA interference
#164NOVEL BIOMARKERS AND TARGETS FOR OVARIAN CARCINOMA
#165Na+/Mg2+ Exchanger
#166Peptide antimicrobials
#167BIOASSAY FOR GENE SILENCING CONSTRUCTS
#168Context Specific Genetic Screen Platform to Aid in Gene Discovery and Target Validation
#169RNAI IN BUDDING YEAST
#170ORGANIC COMPOUNDS
#171COMPOSITIONS AND METHODS FOR MAMMALIAN GENETICS AND USES THEREOF
#172Methods for transfecting nucleic acid into live cells
#173Methods for phototransfecting nucleic acids into live cells
#174RNA sequence-specific mediators of RNA interference
#175SYSTEM AND METHOD FOR PRODUCING FUNCTIONALLY DISTINCT NUCLEIC ACID LIBRARY ENDS THROUGH USE OF DEOXYINOSINE
#176Mixed library parallel gene mapping quantitative micro-array technique for genome-wide identification of trait conferring genes
#177Engineering complex microbial phenotypes with transcription enhancement
#178RNA sequence-specific mediators of RNA interference
#179RNA sequence-specific mediators of RNA interference
#180RNAI BASED SELECTION SYSTEM
#181RNA interference mediating small RNA molecules
#182ENGINEERING COMPLEX MICROBIAL PHENOTYPES WITH SUCCESSIVE INTEGRATIONS OF EXOGENOUS DNA (SIEDNA)
#183RNA sequence-specific mediators of RNA interference
#184RNA sequence-specific mediators of RNA interference
#185BULKED MUTANT ANALYSIS (BMA)
#186TRANSCRIPTION FACTOR DECOYS
#187RNA sequence-specific mediators of RNA interference
#188RNA sequence-specific mediators of RNA interference
#189RNA sequence-specific mediators of RNA interference
#190PEPTIDE MODULATORS OF CELLULAR PHENOTYPE AND BI-NUCLEIC ACID FRAGMENT LIBRARY
#191Genes and uses for plant enhancement
#192METHODS TO TREAT SOLID TUMORS
#193Mutations caused by activation-induced cytidine deaminase
#194RNA interference mediating small RNA molecules
#195RNA interference mediating small RNA molecules
#196RNA interference mediating small RNA molecules
#197RNA interference mediating small RNA molecules
#198RNA interference mediating small RNA molecules
#199Yeast cells expressing TAR DNA-binding protein 43 and uses therefor
#200Methods for cloning and manipulating genomes
#201Methods for cloning and manipulating genomes
#202Methods of genome installation in a recipient host cell
#203RNA interference mediating small RNA molecules
#204RNA interference mediating small RNA molecules
#205RNA interference mediating small RNA molecules
#206Transcription factor decoys, compositions and methods
#207ORGANIC COMPOUNDS
#208RNA interference mediating small RNA molecules
#209Combinatorial discovery of enzymes with utility in biomass transformation
#210RNA interference mediating small RNA molecules
#211Global transcription machinery engineering
#212ONCOGENOMICS-BASED RNAi SCREEN AND USE THEREOF TO IDENTIFY NOVEL TUMOR SUPPRESSORS
#213BIOASSAY FOR GENE SILENCING CONSTRUCTS
#214METHODS FOR SCREENING OF NOVEL FUNCTIONS OF RECEPTOR LIKE KINASES
#215PROCESSES FOR IMPROVED STRAIN ENGINEERING
#216Extranuclear RNA splicing in neuronal dendrites
#217Isoprenoid compounds
#218Method for production of isoprenoid compounds
#219METHODS OF SCREENING FOR AND MAPPING PHENOTYPIC AND GENOTYPIC VARIATIONS IN CELLS
#220Yeast-based assay for measuring the functional activity of an HIV-1 protease in response to an antiviral agent
#221RNA INTERFERENCE MEDIATING SMALL RNA MOLECULES
#222MICROSTRUCTURES AND USE THEREOF FOR THE DIRECTED EVOLUTION OF BIOMOLECULES
#223SELECTION OF BIOCATALYSTS FOR CHEMICAL SYNTHESIS
#224RNA sequence-specific mediators of RNA interference
#225Epigenetic modification of cell phenotype, fate and/or function by RNA transfer
#226Transcriptional engineering of
#227RNA Interference Mediating Small RNA Molecules
#228METHOD FOR DETECTING INTRACYTOPLASMIC PROTEIN/PROTEIN INTERACTIONS
#229Methods and compositions for increasing biological molecule stability
#230MAMMALIAN GENES INVOLVED IN VIRAL INFECTION AND TUMOR SUPPRESSION
#231Compositions and methods for identifying transforming and tumor suppressor genes
#232Chromosome manipulation method
#233Mechanosensitive ion channels and methods of use
#234Methods for modulating cellular and organismal phenotypes
#235RNA interference mediating small RNA molecules
#236Identification of genetic alterations that modulate drug sensitivity in cancer treatments
#237Methods and compositions for RNA interference
#238RNA sequence-specific mediators of RNA interference
#239Whole Genome Evolution Technology Applied To Improve Protein And Antibody Yields By Cells
#240SINGLE PROMOTER INHIBITOR
#241Preventing stress-induced apoptosis in plants
#242Methods and Compositions for Homozygous Gene Inactivation Using Collections of Pre-Defined Nucleotide Sequences Complementary Chromosomal Transcripts
#243Extranuclear RNA splicing in neuronal dendrites
#244Mechanosensitive ion channels and methods of use
#245Methods for identifying a biosynthetic pathway gene product
#246RNA interference mediating small RNA molecules
#247Methods for identifying genes that increase yeast stress tolerance, and use of these genes for yeast strain improvement
#248Global transcription machinery engineering
#249Heirarchical assembly methods for genome engineering
#250RNA sequence-specific mediators of RNA interference
#251RNA sequence-specific mediators of RNA interference
#252RNA sequence-specific mediators of RNA interference
#253RNA sequence-specific mediators of RNA interference
#254Randomized libraries of zinc finger proteins
#255High-throughput screening of expressed DNA libraries in filamentous fungi
#256Microorganism genomics, compositions and methods related thereto
#257Methods and compositions for screening for modulators of IgE synthesis, secretion and switch rearrangement
#258Randomized libraries of zinc finger proteins
#259Methods of producing a library and methods of selecting polynucleotides of interest
#260Methods and compositions for screening for altered cellular phenotypes
#261Microstructures and use thereof for the directed evolution of biomolecules
#262Methods and compositions for RNA interference
#263Screening methods
#264Mixed-library parallel gene mapping quantitative micro-array technique for genome-wide identification of trait conferring genes
#265Protein activity screening of clones having DNA from uncultivated microorganisms
#266Identification of aging genes through large-scale analysis
#267Means for identifying neisseria meningitidis-specific genes
#268Method for the expression of unknown environmental DNA into adapted host cells
#269Gene identification method
#270Mammalian genes involved in viral infection and tumor suppression
#271RNA interference mediating small RNA molecules
#272RNA interference mediating small RNA molecules
#273Method for identification of the location of mutations in whole genomes
#274Combinatorial enzymatic complexes
#275Method for evolving a cell having desired phenotype and evolved cells
#276Mutations caused by activation-induced cytidine deaminase
#277Methods and compositions for identifying peptide aptamers capable of altering a cell phenotype
#278High-throughput transcriptome and functional validation analysis
#279Method for determination of gene function
#280Methods for screening for transdominant effector peptides and RNA molecules
#281Methods for genome annotation
#282RNA interference mediating small RNA molecules
#283Method of determining the function of nucleotide sequences and the proteins they encode by transfecting the same into a host