109048 ⎘
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor; Recombinant DNA-technology; DNA or RNA fragments; Modified forms thereof Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
RNAi-mediated inhibition of H1F1A for treatment of ocular angiogenesis
#12002BLOCKING OF GENE EXPRESSION IN EUKARYOTIC CELLS
#12003CANCER CELL IDENTIFICATION MARKER AND CANCER CELL PROLIFERATION INHIBITOR
#12004Targeting agent for cancer cell or cancer-associated fibroblast
#12005siRNA targeting serine/threonine kinase 12 (STK12 or aurora B kinase)
#12006siRNA-mediated gene silencing with viral vectors
#12007Osteoarthritis biomarkers and uses thereof
#12008Method of treating diabetes
#12009Host cell protein knock-out cells for production of therapeutic proteins
#12010MicroRNAome
#12011RAS-MEDIATED EPIGENETIC SILENCING EFFECTORS AND USES THEREOF
#12012Oncogenic ALL-1 fusion proteins for targeting Drosha-mediated microRNA processing
#12013Compositions and Methods for the Treatment of Diseases Associated with Aberrant Cilia Assembly and Regulation
#12014ANTISENSE ANTIBACTERIAL METHOD AND COMPOUND
#12015DOUBLE-STRANDED OLIGONUCLEOTIDES
#12016Therapeutic Agent for Neuroblastoma Targeting ARID3b
#12017Compositions and methods for siRNA inhibition of HIF-1 α
#12018Methods and compositions for regulating iron homeostasis by modulation of BMP-6
#12019COMPOSITIONS AND METHODS FOR THE INHIBITION OF CRIPTO / GRP78 COMPLEX FORMATION AND SIGNALING
#12020Therapeuting compositions comprising an RNAi agent and a neurotrophic factor and methods of use thereof
#12021Antisense oligonucleotides directed against connective tissue growth factor and uses thereof
#12022RNA interference mediated inhibition of GRB2 associated binding protein (GAB2) gene expression using short interfering nucleic acid (siNA)
#12023Multiple exon skipping compositions for DMD
#12024MODULATION OF eIF4E EXPRESSION
#12025Lipid formulations for nucleic acid delivery
#12026Inhibition of autophagy genes in cancer chemotherapy
#12027Treatment of inflammation using BST2 inhibitor
#12028METHODS AND COMPOSITIONS FOR MODULATING THE MIRNA PATHWAY
#12029Method of using gold nanorods-siRNA complexes
#12030Therapeutic intervention in a genetic disease in an individual by modifying expression of an aberrantly or abnormally expressed gene
#12031Compositions and methods for inhibiting expression of transthyretin
#12032Methods and compositions for the inhibition of Stat5 in prostate cancer cells
#12033Use of a galectin-1-targeted RNAi-based approach for the treatment of cancer
#12034MODIFICATION OF AMYLOID-BETA LOAD IN NON-BRAIN TISSUE
#12035siRNA targeting beta secretase (BACE)
#12036SiRNA targeting myeloid differentiation primary response gene (88) (MYD88)
#12037Modulation of HIF1-beta expression
#12038RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (siNA)
#12039Therapeutic targets and molecules
#12040Microrna molecules
#12041Methods for treating hematopoietic malignancies
#12042Compounds and methods for down-regulating Wrap53 protein by RNA interference
#12043METHODS INVOLVING LEF-1 REGULATION AND USE OF LEF-1 OR COMPOUNDS ALTERING LEF-1 SIGNALLING FOR TREATING OR PREVENTING DISEASES
#12044siRNA targeting vascular endothelial growth factor (VEGF)
#12045siRNA targeting connective tissue growth factor (CTGF)
#12046Methods of obtaining active antisense compounds
#12047Processes and Compositions for Liposomal and Efficient Delivery of Gene Silencing Therapeutics
#12048THERAPEUTIC AGENT FOR PERIODONTAL DISEASE AND ALVEOLAR BONE LOSS DUE TO SURGERY
#12049Treatment of apolipoprotein-A1 related diseases by inhibition of natural antisense transcript to apolipoprotein-A1
#12050H19 silencing nucleic acid agents for treating rheumatoid arthritis
#12051METHODS FOR MODULATING EMBRYONIC STEM CELL DIFFERENTIATION
#12052Composition and methods for modulating cell proliferation and cell death
#12053Methods of modulating the negative chemotaxis of immune cells
#12054RNA interference mediated inhibition of muscarinic colinergic receptor gene expression using short interfering nucleic acid (siNA)
#12055MicroRNA molecules
#12056NOVEL NUCLEIC ACID
#12057RNA interference mediated inhibition of matrix metalloproteinase 13 (MMP13) gene expression using short interfering nucleic acid (siNA)
#12058Nuclear targeting sequences
#12059SiRNA targeting fructose-1, 6-bisphosphatase 1 (FBP1)
#12060ANNEXIN II COMPOSITIONS FOR TREATING OR MONITORING INFLAMMATION OR IMMUNE-MEDIATED DISORDERS
#12061Biomarker specific to brain/nerve or specific to neuronal differentiation
#12062Lentiviral vectors allowing RNAi mediated inhibition of GFAP and vimentin expression
#12063Methods of Inhibiting Tumor Cell Proliferation with FoxM1 siRNA
#12064Regulation of lipid droplet formation by modulation of FIT1 and FIT2 and uses thereof
#12065Inhibitor Nucleic Acids
#12066Oligomeric compounds for the modulation of HIF-1alpha expression
#12067MicroRNA molecules
#12068COMPOUNDS AND METHODS FOR MODULATING PROTEIN EXPRESSION
#12069METHOD AND KIT FOR EFFICIENT REPROGRAMMING OF SOMATIC CELLS
#12070Tripartite oligonucleotide complexes and methods for gene silencing by RNA interference
#12071MODULATION OF MYELOID DIFFERENTATION PRIMARY RESPONSE GENE 88 (MYD88) EXPRESSION BY ANTISENSE OLIGONUCLEOTIDES
#12072Bacteria mediated gene silencing
#12073Compositions and methods for modulating expression of gene products
#12074METHODS OF MODULATING EPITHELIAL-MESENCHYMAL TRANSITION AND MESENCHYMAL-EPITHELIAL TRANSITION IN CELLS AND AGENTS USEFUL FOR THE SAME
#12075Microrna molecules
#12076MicroRNA molecules
#12077Spinal muscular atrophy (SMA) treatment via targeting of splice site inhibitory sequences
#12078Compositions and Methods for Inhibiting Expression of Eg5 and VEGF Genes
#12079Method of treating cancer with an RPN2 gene expression inhibitor
#12080siRNA targeting spleen tyrosine kinase
#12081siRNA targeting superoxide dismutase 1 (SOD1)
#12082NUCLEIC ACID CONSTRUCTS AND METHODS FOR SPECIFIC SILENCING OF H19
#12083Isoform of bruton's tyrosine kinase (BTK) protein
#12084METHOD OF EVALUATING ANTIWRINKLE SUBSTANCE AND METHOD OF ASSESSING THE SKIN
#12085Systems and method for configuring display resolution in a terminal server environment
#12086Use of a truncated eIF-5A1 polynucleotide to induce apoptosis in cancer cells
#12087Sensizitation of cancer cells to therapy using siNA targeting genes from the 1p and 19q chromosomal regions
#12088Sequence of dsRNA: ATN-RNA specific for tenascin-C
#12089siRNA targeting TATA box binding protein (TBP)-associated factor (TAF1)
#12090Efficient method for nuclear reprogramming
#12091Methods and Compositions related to HIF-1 alpha
#12092siRNA targeting amyloid beta (A4) precursor protein (APP)
#12093COMPOSITIONS AND THEIR USES DIRECTED TO HUNTINGTIN
#12094Chemically modified oligonucleotides
#12095METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA
#12096Mitochondrial function of prohibitin 2 (PHB2)
#12097COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF FACTOR V LEIDEN MUTANT GENE
#12098siRNA targeting proto-oncogene MET
#12099Multi-microRNA methods and compositions
#12100Apoptotic cell-mediated transfection of mammalian cells with interfering RNA
#12101Nematode Control
#12102Treatment of neurodegenerative disease through intracranial delivery of SIRNA
#12103siRNA targeting TIE-2
#12104Methods and compositions for treating and diagnosing diseases
#12105Ubiquitin regulatory elements
#12106Hydroxymethyl substituted RNA oligonucleotides and RNA complexes
#12107siRNA targeting coatomer protein complex, subunit beta 2 (CPOB2)
#12108Brachyury polypeptides and methods for use
#12109Methods and Compositions for Targeting c-Rel
#12110Application of actin-binding protein to disease associated with cell motility
#12111Regulation of integrin surface expression
#12112siRNA targeting tumor protein 53 (p53)
#12113METHODS AND COMPOSITIONS FOR GENERATING SPORULATION DEFICIENT BACTERIA
#12114RIBOSWITCHES, METHODS FOR THEIR USE, AND COMPOSITIONS FOR USE WITH RIBOSWITCHES
#12115Isolated MCPIP and Methods of Use
#12116EFFICIENT REDUCTION OF TARGET RNA'S BY SINGLE- AND DOUBLE-STRANDED OLIGOMERIC COMPOUNDS
#12117Carrier nanoparticles and related compositions, methods and systems
#12118Method of treating a cancer by administering A 2′,5′-oligoadenylate analog
#12119Oligoribonucleotides and Methods of use Thereof for Treatment of Cardiovascular Disease
#12120Nucleic acid molecules and collections thereof, their application and modification
#12121Production of functional proteins: balance of shear stress and gravity
#12122Triggered RNAi
#12123USE OF INHIBITORS OF LEUKOTRIENE B4 RECEPTOR BLT2 FOR TREATING ASTHMA
#12124METHODS AND COMPOSITIONS FOR INHIBITING THE FUNCTION OF POLYNUCLEOTIDE SEQUENCES
#12125AMELIORATING AGENT FOR INSULIN RESISTANCE
#12126siRNA targeting survivin
#12127METHOD OF IDENTIFYING MICRO-RNA TARGETS
#12128RNAi expression constructs
#12129Compositions and Methods of Using siRNA to Knockdown Gene Expression and to Improve Solid Organ and Cell Transplantation
#12130Inhibition of SOX9 function in the treatment of proteoglycan-associated pathophysiological conditions
#12131Compositions and Methods to Treat Bone Related Disorders
#12132siRNA targeting kinase insert domain receptor (KDR)
#12133Modulators of cell migration and methods of identifying same
#12134Methods and compositions for the treatment of eye disorders with increased intraocular pressure
#12135SiRNA targeting ras-related nuclear protein RAN
#12136OLIGONUCLEOTIDES FOR MODULATING TARGET RNA ACTIVITY
#12137SiRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B)
#12138Methods and compositions related to eosinophil regulation
#12139Antisense RNA for treating cancer and inhibition of metastasis and vectors for antisense sequestration
#12140Structural-based inhibitors of the glutathione binding site in aldose reductase, methods of screening therefor and methods of use
#12141COMPOUND AND METHOD FOR TREATING MYOTONIC DYSTROPHY
#12142siRNA targeting histamine receptor H1
#12143Short interfering ribonucleic acid (siRNA) with improved pharmacological properties
#12144NUCLEIC ACID COMPOUNDS FOR INHIBITING HIF1A GENE EXPRESSION AND USES THEREOF
#12145Negative regulation of NK cell functions by EAT-2, a sap-related adaptor expressed in innate immune cells
#12146COMPOSITIONS AND METHODS FOR IDENTIFYING AND TARGETING CANCER CELLS OF ALIMENTARY CANAL ORIGIN
#12147METHODS AND COMPOSITIONS FOR THE UTILIZATION AND TARGETING OF OSTEOMIMICRY
#12148RNAi for the control of insects and arachnids
#12149Compositions and Methods Using RNA Interference for Control of Nematodes
#12150RNA INTERFERENCE MEDIATING SMALL RNA MOLECULES
#12151siRNA targeting hypoxia-inducible factor 1
#12152Inhibiting serum response factor (SRF) to improve insulin sensitivity
#12153MicroRNA (miRNA) for the diagnosis and treatment of heart diseases
#12154MicroRNA biomarkers for human breast and lung cancer
#12155Compositions and use of EPAS1 inhibitors
#12156Methods and Compositions for Cellular Reprogramming
#12157COMPOSITIONS AND METHODS FOR SPECIFICALLY SILENCING A TARGET NUCLEIC ACID
#12158Biologically active molecules, particularly based on PNA and siRNA, method for the cell-specific activation thereof, and application kit to be administered
#12159Specific GRP78 expression-inhibition RNAi sequence, medicine thereof and method thereof
#12160Methods and sequences to suppress primate huntington gene Expression
#12161ANNEXIN II COMPOSITIONS FOR TREATING OR MONITORING INFLAMMATION OR IMMUNE-MEDIATED DISORDERS
#12162METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA
#12163METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA
#12164METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA
#12165Pharmaceutical Composition
#12166METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA
#12167METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA
#12168Compositions comprising siRNA and plasmids
#12169siRNA targeting myeloid cell Leukemia sequence 1
#12170siRNA targeting polo-like Kinase-1 (PLK-1)
#12171METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA
#12172Multivalent rna nanoparticles for delivery of active agents to a cell
#12173Diagnosis of nasopharyngeal carcinoma and suppression of nasopharyngeal carcinoma invasion
#12174Compositions and methods for inhibiting translation of a Mect1-MAML2 chimeric gene
#12175Promoters exhibiting endothelial cell specificity and methods of using same
#12176Modulation of gene expression through endogenous small RNA targeting of gene promoters
#12177METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA
#12178COMPOUNDS AND METHODS FOR MODULATING EXPRESSION OF CRP
#12179COMPOUNDS AND METHODS FOR MODULATING EXPRESSION OF SGLT2
#12180ANTISENSE MODULATION OF APOLIPOPROTEIN B EXPRESSION
#12181siRNA targeting interleukin-1 receptor-associated kinase 4 (IRAK4)
#12182METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA
#12183METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA
#12184Optical sorting method
#12185POLYPYRIMIDINE-TRACT BINDING PROTEIN (PTB) AS A BIOMARKER AND TARGET FOR THE DIAGNOSIS AND TREATMENT OF CANCER
#12186METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA
#12187KLF6 ALTERNATIVE SPLICE FORMS AND A GERMLINE KLF6 DNA POLYMORPHISM ASSOCIATED WITH INCREASED CANCER RISK
#12188RNAi-mediated inhibition of spleen tyrosine kinase-related inflammatory conditions
#12189Snow shovel with spring loaded shovel head
#12190NUCLEIC ACIDS FOR EXPRESSING A POLYNUCLEOTIDE OF INTEREST IN MAMMALIAN CANCER CELLS
#12191β-TrCP1, β-TrCP2 and RSK1 or RSK2 inhibitors and methods for sensitizing target cells to apoptosis
#12192Compounds and methods for modulating expression of PTP1B
#12193Methods for modulating bone formation and mineralization by modulating KRC activity
#12194Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
#12195Methods to predict and prevent resistance to taxoid compounds
#12196RNAi modulation of ApoB and uses thereof
#12197Assay
#12198METHOD FOR PREPARING DIFFERENTIATED AVIAN CELLS AND GENES INVOLVED IN MAINTAINING PLURIPOTENCY
#12199RIBOZYME MEDIATED STABILIZATION OF POLYNUCLEOTIDES
#122002-Azapurine compounds and their use
#12201Compounds and methods for modulating expression of GCCR
#12202siRNA targeting TNFα
#12203Methods for controlling pests using RNAi
#12204Compositions and methods for the treatment of diseases associated with aberrant cilia assembly and regulation
#12205Compounds and methods for modulating expression ApoB
#12206Compounds and methods for modulating expression of GCGR
#12207CONJUGATED DOUBLE STRAND COMPOSITIONS FOR USE IN GENE MODULATION
#12208Use of low doses of oligonucleotides antisense to TGF-β genes in the treatment of brain tumors
#12209Compounds and methods for modulating expression of PCSK9
#12210Immuno-RNA-constructs
#12211Preparation for the Prevention and/or Treatment of a Tissue Change of Mesenchymal Origin
#12212Modulators of alpha-synuclein toxicity
#12213Treatment of metastatic tumors
#12214Transgenic plant-based methods for plant pests using RNAi
#12215Pharmaceutical compositions for treatment of microRNA related diseases
#12216Regulation of epigenetic control of gene expression
#12217Dsrna as Insect Control Agent
#12218Polynucleotides and polypeptide sequences involved in the process of bone remodeling
#12219Nucleotide sequences
#12220siRNA targeting KRAS
#12221Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
#12222METHOD FOR INTRODUCING SIRNA INTO CELLS BY PHOTOCHEMICAL INTERNALISATION
#12223MODULATION OF STAT 6 EXPRESSION
#12224COMPOUNDS AND METHODS FOR MODULATING EXPRESSION OF DGAT2
#12225Cell penetrating peptides for intracellular delivery of molecules
#12226Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
#12227Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
#12228siRNA targeting transducin (beta)-like 3 (TBL3)
#12229Antibodies and processes for preparing the same
#12230Gene silencing
#12231Ligand-conjugated monomers
#12232Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-Coding RNAs
#12233Potent LNA oligonucleotides for the inhibition of HIF-1a expression
#12234MODIFIED OLIGONUCLEOTIDES FOR TELOMERASE INHIBITION
#12235PHARMACEUTICAL COMPOSITION FOR THE DIAGNOSIS, PREVENTION OR TREATMENT OF A TUMORAL PATHOLOGY COMPRISING AN AGENT MODULATING THE POLYMERIZATION STATE OF ACTIN
#12236METHODS AND COMPOSITIONS FOR USE IN PREPARRING siRNAs
#12237Gene silencing
#12238Random RNAi libraries, methods of generating same, and screening methods utilizing same
#12239siRNA targeting v-myc myelocytomatosis viral oncogene homolog (MYC)
#12240Compositions and methods related to miRNA modulation of neovascularization or angiogenesis
#12241STABILIZED SIRNAS AS TRANSFECTION CONTROLS AND SILENCING REAGENTS
#12242FERRITIN AS A THERAPEUTIC TARGET IN ABNORMAL CELLS
#12243Delivery Of Double-Stranded RNA Into The Central Nervous System
#12244Use of nucleic acids with reduced pressure therapy
#12245MicroRNA and methods for inhibiting same
#12246siRNA targeting inner centromere protein antigens (INCENP)
#12247Compositions and methods for inhibiting expression of XBP-1 gene
#12248Antisense modulation of C-reactive protein expression
#12249HUMAN RNASE III AND COMPOSITIONS AND USES THEREOF
#12250Modified siRNA molecules and uses thereof
#12251Methods for multiplexing recombinase polymerase amplification
#12252Kit for detection of telomerase reverse transcriptase nucleic acids
#12253Caspase-8 and inflammation, infection and wound healing
#12254Compositions and methods for the suppression of target polynucleotides from lepidoptera
#12255Conjugates and compositions for cellular delivery
#12256Double helical oligonucleotides interfering with mRNA used as effective anticancer agents
#12257COMPOSITIONS AND THEIR USES DIRECTED TO HSP27
#12258Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
#12259MONOCLONAL ANTIBODIES FOR INHIBITION OF LAMININ-8 EXPRESSION TO INHIBIT HUMAN GLIOMAS
#12260Method and constructs for delivering double stranded RNA to pest organisms
#12261Compositions and siRNAs for inhibiting C/EBPbeta
#12262Multifunction nanoconjugates for imaging applications and targeted treatment
#12263METHODS OF DIAGNOSING ALZHEIMER'S DISEASE AND MARKERS IDENTIFIED BY SET ASSOCIATION
#12264Chimeric oligomeric compounds comprising alternating regions of northern and southern conformational geometry
#12265Method for the modulation of function of transcription factors
#12266Natural antisense and non-coding RNA transcripts as drug targets
#12267GENE KNOCK-DOWN BY INTRACELLULAR EXPRESSION OF APTAMERS
#12268Sequence diversity generation in immunoglobulins
#12269COMPOSITIONS AND METHODS RELATED TO miR-16 AND THERAPY OF PROSTATE CANCER
#12270siRNA targeting gremlin
#12271Compositions comprising inhibitors of RNA binding proteins and methods of producing and using same
#12272Methods of diagnosing alzheimer's disease and markers identified by set association
#12273Triggered RNAi
#12274Folate conjugates
#12275SM-PROTEIN BASED SECRETION ENGINEERING
#12276RNA Interference Mediated Inhibition of Adenosine A1 Receptor (ADORA1) Gene Expression Using Short Interfering Nucleic Acid (siNA)
#12277Efficient method for nuclear reprogramming
#12278Identification of micro-RNAS involved in neuromuscular synapse maintenance and regeneration
#12279Anti-myosin Va siRNA and skin depigmentation
#12280Multitargeting Interfering RNAs And Methods Of Their Use And Design
#12281Compositions and methods for diagnosing and treating melanoma
#12282Methods and compositions for increasing RNA interference
#12283Signal activated RNA interference
#12284COMPOSITIONS AND METHODS FOR INHIBITING HIV INFECTIONS BY INHIBITING LEREPO4 AND GLIPR
#12285Compounds for Hydrolyzing Ribonucleic Acids (RNA's)
#12286ALLELE SUPPRESSION
#12287Use Of A Growth-Stimulating Protein
#12288Prognosis and treatment of breast cancer
#12289Methods for modulating de novo hepatic lipogenesis by modulating XBP-1 activity
#12290Induction of exon skipping in eukaryotic cells
#12291siRNA targeting connexin 43
#12292miR-34 Regulated Genes and Pathways as Targets for Therapeutic Intervention
#12293METHODS AND PRODUCTS TO TARGET, CAPTURE AND CHARACTERIZE STEM CELLS
#12294Method to Inhibit the Propagation of an Undesired Cell Population
#12295Micro-RNAs that modulate smooth muscle proliferation and differentiation and uses thereof
#122962' Deoxy-2'-Alkylnucleotide Containing Nucleic Acid
#12297Modulation of the Transcription of Pro-Inflammatory Gene Products
#12298Oligomeric compounds and compositions for the use in modulation of microRNAs
#12299Compositions and methods for treatment of prostate and other cancers
#12300Autonomously Replicating KSHV CIS-Acting Elements