109113 ⎘
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor; Recombinant DNA-technology; Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
Sub-classes:Method for Editing Bovine Gene Based on Pro-iCHI
#2Cell-free DNA for Use in Genotyping
#3METHODS FOR DERIVATION AND PROPAGATION OF AVIAN PLURIPOTENT STEM CELLS AND APPLICATIONS THEREOF
#4PROCESS OF TRANSFECTING PRIMORDIAL GERM CELLS IN AN AVIAN
#5MANIPULATION OF ZONA PELLUCIDA TO FACILITATE DELIVERY OF NUCLEIC ACIDS FOR GENE EDITING IN EMBRYO
#6GENE-EDITING METHODS FOR EMBRYONIC STEM CELLS
#7METHODS FOR MAKING GENETIC EDITS
#8GENERATION OF SURROGATE SIRES AND DAMS BY ABLATION OF ENDOGENOUS GERMLINE
#9Method for Constructing Ptgds Gene Knockout Rat Model with Spontaneous Kidney Yin Deficiency
#10Process for using CRISPR to transfect primordial germ cells in avians
#11METHODS AND COMPOSITIONS FOR USE OF MITOCHONDRIAL THERAPIES TO IMPROVE FEMALE REPRODUCTIVE POTENTIAL
#12GENE EDITING TO CORRECT ANEUPLOIDIES AND FRAME SHIFT MUTATIONS
#13GENETIC MODIFICATION NON-HUMAN ORGANISM, EGG CELLS, FERTILIZED EGGS, AND METHOD FOR MODIFYING TARGET GENES
#14METHODS FOR REGULATING POTENCY OF PLURIPOTENT STEM CELLS AND APPLICATIONS THEREOF
#15Methods for making genetic edits
#16Device for collecting and culturing fish embryos and method for evaluating combined toxicity of thiamethoxam and tetraconazole
#17PRODUCTION METHOD FOR ANIMAL MODELS WITH DISEASE ASSOCIATED PHENOTYPES
#18COMPOSITIONS AND METHODS FOR ENHANCING SPERM FUNCTION
#19METHODS FOR MAKING AND USING MODIFIED OOCYTES
#20COMPOSITIONS AND METHODS FOR EMBRYONIC GENE EDITING IN VITRO
#21HUMAN GENE CORRECTION
#22Process of transfecting primordial germ cells in an avian
#23Magnetic Nanoparticles for use in Assisted Reproduction
#24INDUCIBLE DISEASE MODELS METHODS OF MAKING THEM AND USE IN TISSUE COMPLEMENTATION
#25COMPOSITIONS AND METHODS FOR EFFICIENT GENOME EDITING
#26Retinoic acid-inducible gene I promoter and compositions and methods relating to same
#27METHODS AND COMPOSITIONS TO INCREASE HUMAN SOMATIC CELL NUCLEAR TRANSFER (SCNT) EFFICIENCY BY REMOVING HISTONE H3-LYSINE TRIMETHYLATION, AND DERIVATION OF HUMAN NT-ESC
#28METHODS OF REPROGRAMMING ANIMAL SOMATIC CELLS
#29Ungulates with genetically modified immune systems
#30SELECTIVE OXIDATION OF 5-METHYLCYTOSINE BY TET-FAMILY PROTEINS
#31SELECTIVE OXIDATION OF 5-METHYLCYTOSINE BY TET-FAMILY PROTEINS
#32SELECTIVE OXIDATION OF 5-METHYLCYTOSINE BY TET-FAMILY PROTEINS
#33Compositions comprising glucosylated hydroxymethylated bases
#34Methods of Genetic Modification of a Cell
#35Method of constructing zebrafish mutants
#36Methods for making and using modified oocytes
#37Methods for identifying hydroxylated bases
#38Process for using crispr to transfect primordial germ cells in avians
#39Selective oxidation of 5-methylcytosine by TET-family proteins
#40METHOD OF PRODUCING INFERTILE FISH AND EGG-PRODUCING AQUATIC ANIMALS AND OF DELIVERING COMPOUNDS INTO EGGS AND EMBRYOS
#41METHODS FOR GENOME EDITING IN ZYGOTES
#42GENETIC MODIFICATION NON-HUMAN ORGANISM, EGG CELLS, FERTILIZED EGGS, AND METHOD FOR MODIFYING TARGET GENES
#43Methods for distinguishing 5-hydroxymethylcytosine from 5-methylcytosine
#44DERIVATION OF EMBRYONIC STEM CELLS AND EMBRYO-DERIVED CELLS
#45SELECTIVE OXIDATION OF 5-METHYLCYTOSINE BY TET-FAMILY PROTEINS
#46SELECTIVE OXIDATION OF 5-METHYLCYTOSINE BY TET-FAMILY PROTEINS
#47Selective oxidation of 5-methylcytosine by TET-family proteins
#48MITOCHONDRIAL MICROINJECTION OF OOCYTES
#49In Vivo Methods for Enhancing Bioenergetic Status in Female Germ Cells
#50Detection of 5-hydroxymethylcytosine by glycosylation
#51Labeling hydroxymethylated residues
#52METHODS AND COMPOSITIONS TO INCREASE HUMAN SOMATIC CELL NUCLEAR TRANSFER (SCNT) EFFICIENCY BY REMOVING HISTONE H3-LYSINE TRIMETHYLATION, AND DERIVATION OF HUMAN NT-ESC
#53Method of producing infertile fish and egg-producing aquatic animals and of delivering compounds into eggs and embryos
#54Production of parthenogenetic stem cells and patient-specific human embryonic stem cells using somatic cell nuclear transfer
#55Androgenetic haploid embryonic stem cell (AG-HAESC), and preparation method and use thereof
#56Method for injectable delivery of a therapeutic agent into a fish embryo
#57Storage method and banking system of NT cell
#58Induced extended pluripotent stem cells, method of making and using
#59Selective oxidation of 5-methylcytosine by TET-family proteins
#60Compositions and Methods for Enhancing Bioenergetic Status in Female Germ Cells
#61Gene knockout method
#62Method of conveniently producing genetically modified non-human mammal with high efficiency
#63Genetically modified rat derived from rat embryonic stem cell
#64HIGH EFFICIENCY, HIGH THROUGHPUT GENERATION OF GENETICALLY MODIFIED MAMMALS BY ELECTROPORATION
#65CYTOPLASMIC TRANSFER TO DE-DIFFERENTIATE RECIPIENT CELLS
#66Production of fertile XY female mice from XY mouse ES cells
#67Selective oxidation of 5-methylcytosine by TET-family proteins
#68METHOD FOR RECONSTRUCTING A NON-HUMAN ANIMAL EMBRYO
#69Nuclear transfer
#70Selective oxidation of 5-methylcytosine by TET-family proteins
#71HUMAN PLURIPOTENT STEM CELLS PRODUCED BY SOMATIC CELL NUCLEAR TRANSFER
#72METHODS OF REPROGRAMMING ANIMAL SOMATIC CELLS
#73Selective oxidation of 5-methylcytosine by TET-family proteins
#74Methods for making and using modified oocytes
#75Method of genetically altering and producing allergy free cats
#76GENERATION OF INDUCED PLURIPOTENT STEM (iPS) CELLS
#77POLAR BODY GENOME RECONSTRUCTED OOCYTES AND PREPARATION METHOD AND USE THEREOF
#78Feeder-free method for culture of bovine and porcine spermatogonial stem cells
#79Promoter-regulated differentiation-dependent self-deleting cassette
#80Production of fertile XY female animals from XY ES cells
#81Method of producing infertile fish and egg-producing aquatic animals and of delivering compounds into eggs and embryos
#82METHODS AND MATERIALS FOR PRODUCING TRANSGENIC ARTIODACTYLS
#83miRNA-regulated differentiation-dependent self-deleting cassette
#84Blastoid, cell line based artificial blastocyst
#85Compositions and Methods for Enhancing Bioenergetic Status in Female Germ Cells
#86Model animal for pregnancy-induced hypertension syndrome, and treatment method therefor
#87Methods of reprogramming animal somatic cells
#88Generation of induced pluripotent stem (iPS) cells
#89Feeder-free method for culture of bovine and porcine spermatogonial stem cells
#90ES cell cytoplasm or ooplasm transfer to rejuventate recipient cells
#91Promoter-regulated differentiation-dependent self-deleting cassette
#92Method of making a chicken with germ cells expressing marker protein
#93Production of fertile XY female animals from XY ES cells
#94Derivation of embryonic stem cells
#95Derivation of embryonic stem cells and embryo-derived cells
#96Human pluripotent embryonic stem cells produced by nuclear transfer using a somatic cell nucleus treated with HVJ-E extract and an oocyte from a donor cycle that produced 15 or fewer oocytes
#97Methods for making and using modified oocytes
#98Composition for a mitotic remodeling of chromosomes
#99Method for producing model animal, and model animal
#100Modulation of meiotic recombination
#101miRNA-regulated differentiation-dependent self-deleting cassette
#102Rat embryonic stem cell
#103SYSTEM AND PROCESS FOR GENETIC AND EPIGENETIC TREATMENT
#104Promoter-regulated differentiation-dependent self-deleting cassette
#105Promoter-regulated differentiation-dependent self-deleting cassette
#106Gynogenetic or androgenetic production of pluripotent cells and cell lines, and use thereof to produce differentiated cells and tissues
#107Compositions and methods relating to non-human animals modified to promote production of selected gametes
#108Generation of Histocompatible Tissues Using Nuclear Transplantation
#109Feeder-free method for culture of bovine and porcine spermatogonial stem cells
#110Sperm cell processing systems
#111System and method for sorting cells
#112System and method for sorting cells
#113CYTOPLASMIC TRANSFER TO DE-DIFFERENTIATE RECIPIENT CELLS
#114Methods of enhancing pluripotentcy
#115Composition and Method for Prolonging the Shelf Life of Banana by Using Interfering RNA
#116Use of RNA interference for the creation of lineage specific ES and other undifferentiated cells and production of differentiated cells in vitro by co-culture
#117Compositions and methods for enhancing bioenergetic status in female germ cells
#118Modulation of oocyte meiotic progression and oocyte activation
#119Method for acquiring genetically identical gamete from lethal fish haploid-derived germ cell via germ line chimera
#120Chimeric rat produced using rat embryonic stem cells in the presence of an ES cell differentiation suppressant
#121METHODS FOR THE COLLECTION AND MATURATION OF OOCYTES
#122Method for Generating Immune-Compatible Cells and Tissues Using Nuclear Transfer Techniques
#123Methods and materials for producing transgenic artiodactyls
#124METHODS AND COMPOSITIONS FOR CELL THERAPY
#125METHODS FOR MAKING EMBRYONIC CELLS, EMBRYOS, AND ANIMALS SENSITIZED TO STRESS
#126Compositions and methods relating to non-human animals modified to promote production of selected gametes
#127Method of Genetically Altering and Producing Allergy Free Cats
#128Rat embryonic stem cell
#129Method for producing pluripotent stem cells
#130METHOD OF DELIVERY OF NUCLEIC ACIDS TO A DEVELOPING EMBRYO
#131Methods for mitochondrial DNA replacement in oocytes
#132Compositions and Methods for Generating Transgenic Animals
#133Production of fertile XY animals from XY ES cells
#134Gynogenetic or androgenetic production of pluripotent cells and cell lines, and use thereof to produce differentiated cells and tissues
#135Use of haploid genomes for genetic diagnosis, modification and multiplication
#136Composition for reprogramming somatic cells to generate induced pluripotent stem cells, comprising Bmi1 and low molecular weight substance, and method for generating induced pluripotent stem cells using the same
#137Generation of Histocompatible Tissues Using Nuclear Transplantation
#138METHOD FOR EVALUATION OF DIFFERENTIATION ABILITY OF STEM CELL
#139Culture systems for ex vivo development
#140METHODS AND MATERIALS FOR PRODUCING TRANSGENIC ARTIODACTYLS
#141Derivation of embryonic stem cells and embryo-derived cells
#142Multipotent Adult Stem Cells, Sources Thereof, Methods of Obtaining and Maintaining Same, Methods of Differentiation Thereof, Methods of Use Thereof and Cells Derived Thereof
#143Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
#144GENERATION OF INDUCED PLURIPOTENT STEM (iPS) CELLS
#145Method for modifying chromosomes
#146Derivation of embryonic stem cells
#147Methods of Reprogramming Animal Somatic Cells
#148COMPOSITIONS AND METHODS FOR GENERATING TRANSGENIC ANIMALS
#149METHOD FOR PRODUCING FOUNDER ANIMAL FOR REPRODUCING ANIMAL HAVING LETHAL PHENOTYPE CAUSED BY GENE MODIFICATION
#150METHOD OF PRODUCING NON-HUMAN MAMMALS
#151Promoter-regulated differentiation-dependent self-deleting cassette
#152miRNA-regulated differentiation-dependent self-deleting cassette
#153Methods Of Producing Pluripotent Stem Cell-Generated Embryos, And Animals Derived Therefrom
#154PRODUCTION OF ANTIBODIES IN AVIAN CELLS
#155METHOD OF PREPARING INDUCED PLURIPOTENT STEM CELLS DEPRIVED OF REPROGRAMMING GENE
#156Methods and compositions for homologous recombination in human cells
#157Generation of Genetically Corrected Disease-free Induced Pluripotent Stem Cells
#158Composition and Method for Prolonging the Shelf Life of Banana by Using Interfering RNA
#159Rabbit nuclear cloning method and uses thereof
#160METHODS FOR CORRECTING MITOTIC SPINDLE DEFECTS AND OPTIMIZING PREIMPLANTATION EMBRYONIC DEVELOPMENTAL RATES ASSOCIATED WITH SOMATIC CELL NUCLEAR TRANSFER IN ANIMALS
#161Stem Cells Derived from Uniparental Embryos and Methods of Use Thereof
#162Assessment Method
#163Use of a cellular extract for a mitotic remodeling of chromosomes
#164Methods of Reprogramming Animal Somatic Cells
#165UNACTIVATED OOCYTES AS CYTOPLAST RECIPIENTS FOR NUCLEAR TRANSFER
#166PARTHENOTE-DERIVED STEM CELLS AND METHODS OF MAKING AND USING THEM
#167Method for Producing Stem Cells or Stel Cell-Like Cells from Mammalian Embryos
#168Sex Selected Equine Intracytoplasmic Sperm Injection Embryo Production System
#169Ungulates with genetically modified immune systems
#170Efficient Somatic Cell Nuclear Transfer In Fish
#171Prion-free transgenic ungulates
#172Compositions And Methods For Generating Transgenic Animals
#173In vitro fertilisation
#174METHOD OF DELIVERY OF NUCLEIC ACIDS TO A DEVELOPING EMBRYO
#175Artificial chromosomes and transchromosomic avians
#176Novel Method for Generating Non-Human ES Animals
#177METHODS FOR FEMALE MAMMALIAN SPERMATOGENESIS AND MALE MAMMALIAN OOGENESIS USING SYNTHETIC NANOBIOLOGY
#178MANIPULATING SP1 ACTIVITY TO IMPROVE THERAPEUTIC CLONING
#179METHODS FOR MAKING AND USING REPROGRAMMED HUMAN SOMATIC CELL NUCLEI AND AUTOLOGOUS AND ISOGENIC HUMAN STEM CELLS
#180Methods and compositions for cell therapy
#181Method to produce cloned embryos and adults from cultured cells
#182Genetically Engineered and Phenotyped Mice and Stem Cell Clones for Producing the Same
#183Chromosome selection
#184Method for modifying chromosomes
#185Method for producing cloned dog
#186Methods for developing animal models
#187Promotor for Introducing Extracellular Substance into Mammalian Ovum and Introduction Method
#188METHODS FOR CORRECTING MITOTIC SPINDLE DEFECTS ASSOCIATED WITH SOMATIC CELL NUCLEAR TRANSFER IN ANIMALS
#189Human parthenogenetic stem cells
#190Assessment method
#191In-vitro method for producing oocytes or eggs having targeted genomic modification
#192Method of Producing Autologous Embryonic Stem Cells
#193Method of nuclear transfer
#194USE OF HAPLOID GENOMES FOR GENETIC DIAGNOSIS, MODIFICATION AND MULTIPLICATION
#195Gynogenetic or androgenetic production of pluripotent cells and cell lines, and use thereof to produce differentiated cells and tissues
#196Derivation of embryonic stem cells and embryo-derived cells
#197Method for introducing an exogenous gene into a stem cell
#198Activation of Nuclear Transfer Embryos
#199Isolation of Stem Cell-Like Cells and Use Thereof
#200Isolation, selection and propagation of animal transgenic stem cells
#201Ungulates with genetically modified immune systems
#202Methods for sorting undifferentiated cells and uses thereof
#203Cloning B and T lymphocytes
#204Construction of Chimera Using En Cells
#205STEM CELLS DERIVED FROM UNIPARENTAL EMBRYOS AND METHODS OF USE THEREOF
#206Co-extruded syringe assembly and method for making the same
#207Integrated in vivo animal experimentation systems
#208Rat embryonic stem cell
#209ELECTROFUSION MICROELECTRODE
#210Sperm cell processing and preservation systems
#211Use of a Composition which Regulates Oxidation/Reduction Reactions Intracellularly and/or Extracellularly in a Staining or Sorting Process
#212Novel culture systems for ex vivo development
#213Method for culturing avian spermatogonial stem cells and avian spermatogonial stem cells prepared thereby
#214Method for producing avian chimera using spermatogonial cells and avian chimera
#215Methods of ungulate nuclear transfer
#216Unactivated oocytes as cytoplast recipients for nuclear transfer
#217Collection Systems for Cytometer Sorting of Sperm
#218Cloning of transgenic unglulates comprising artificial chromosomes
#219System and process for genetic and epigenetic treatment
#220Use of RNA interference for the creation of lineage specific ES and other undifferentiated cells and production of differentiated cells in vitro by co-culture
#221Embryonically modified animal and method of constructing the same
#222Method for improving germline transmission efficiency of avian primordial germ cells
#223Methods for cloning mammals using reprogrammed donor chromatin or donor cells
#224Derivation of embryonic stem cells
#225Method and system for fusion and activation following nuclear transfer in reconstructed embryos
#226Artificial chromosomes and transchromosomic avians
#227Non-inbred embryonic stem cells having good developmental potential
#228Injection of caprine sperm factor (cSF), phospholipase C zeta (PLCzeta) and adenophostin A as alternative methods of activation during nuclear transfer in the caprine species
#229Methods of developing a stem cell line
#230Ungulates with genetically modified immune systems
#231Novel culture systems for ex vivo development
#232Method for producing cell lines and organs by means of differentiable cells
#233Depletion of endogenous primordial germ cells in avian species
#234Methods and compositions for cell therapy
#235Mammalian cultured inner cell mass cell culture using a g1 cell as nuclear donor
#236Carbohydrate determinant selection system for homologous recombination
#237Generation of histocompatible tissues using nuclear transplantation
#238Culture systems for ex vivo development
#239Novel mutated mammalian cells and animals
#240Method for generating immune-compatible cells and tissues using nuclear transfer techniques
#241Prenatal screening
#242Method to decrease the rate of polyspermy in IVF
#243Nuclear transfer embryo formation method
#244Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
#245Preparation and selection of donor cells for nuclear transplantation
#246In vitro fertilisation
#247Prion-free transgenic ungulates
#248Pluripotent mammalian cells
#249Electrofusion microelectrode
#250Isolation, selection and propagation of animal transgenic stem cells
#251Fish produced by nuclear transfer from cultured cells
#252Systems of transferring embryos and managing recipients
#253Method of handling an oocyte during in vitro fertilization
#254Genetic modification of C57 mice
#255Unactivated oocytes as cytoplast recipients for nonprimate mammalian and pig nuclear transfer
#256Rabbit nuclear cloning method and uses thereof
#257Methods for cloning mammals using remodeling factors
#258Method to produce a hybrid cell having a single mitochondrial genotype
#259Serial nuclear transfer of ungulate embryos
#260Embryonic or stem-like cell lines produced by cross species nuclear transplantation
#261Differentiation of human embryonic stem cells in avian embryos
#262Method of producing non-human mammals
#263Sex- specific selection of sperm from transgenic animals
#264Generation of transgenic mice by transgene-mediated rescue of spermatogenesis
#265Prenatal screening
#266Unactivated ungulate oocytes to produce a cloned ungulate by nuclear transfer
#267Immune cloning and uses thereof
#268Enucleation of avian eggs by gamma irradiation
#269Compositions for the derivation of germ cells from stem cells and methods of use thereof