ClassID:

109103

C12N2015/8518 - CPC Classification

Classification description:

Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor; Recombinant DNA-technology; Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression; Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic expressing industrially exogenous proteins, e.g. for pharmaceutical use, human insulin, blood factors, immunoglobulins, pseudoparticles

Recent Application in this class:
#1
20260139021
2026-05-21

VIRAL EXPRESSION CONSTRUCT COMPRISING A FIBROBLAST GROWTH FACTOR (FGF21) CODING SEQUENCE

#2
20260123611
2026-05-07

GENETICALLY MODIFIED MOUSE FOR PREPARING ANTIBODY AND METHOD FOR PREPARING GENETICALLY MODIFIED MOUSE

#3
20260117252
2026-04-30

Circular RNA For Translation In Eukaryotic Cells

#4
20260078400
2026-03-19

Circular RNA For Translation In Eukaryotic Cells

#5
20260078197
2026-03-19

GENETICALLY MODIFIED NON-HUMAN ANIMALS AND METHODS FOR PRODUCING HEAVY-CHAIN ANTIBODIES

#6
20260071006
2026-03-12

MICE THAT MAKE VL BINDING PROTEINS

#7
20260068860
2026-03-12

NON-HUMAN ANIMALS HAVING AN ENGINEERED IMMUNOGLOBULIN LAMBDA LIGHT CHAIN LOCUS

#8
20260043020
2026-02-12

BINDING MEMBERS WITH ALTERED DIVERSITY SCAFFOLD DOMAINS

#9
20260022395
2026-01-22

HUMAN IMMUNOGLOBULIN COMMON LIGHT CHAIN TRANSGENE CONSTRUCTS AND USES THEREOF

#10
20260008860
2026-01-08

OX40-Binding Polypeptides and Uses Thereof

#11
20250386808
2025-12-25

NON-HUMAN ANIMALS EXPRESSING EXOGENOUS TERMINAL DEOXYNUCLEOTIDYLTRANSFERASE

#12
20250366449
2025-12-04

MOUSE ARTIFICIAL CHROMOSOME VECTOR AND USE THEREOF

#13
20250346650
2025-11-13

ANTIBODIES WITH ENGINEERED CH2 DOMAINS, COMPOSITIONS THEREOF AND METHODS OF USING THE SAME

#14
20250340611
2025-11-06

ANTI-KRAS-G12D T CELL RECEPTORS

#15
20250327091
2025-10-23

METHOD FOR PRODUCING RECOMBINANT PROTEINS IN INSECTS FOR INTEGRATION IN HUMAN THERAPEUTICS

#16
20250305020
2025-10-02

Silk Gland Recombinant Expression Vector of Silkworm (Bombyx Mori) Expressing Human Epidermal Growth Factor, Preparation Method and Use Thereof

#17
20250280805
2025-09-11

METHODS FOR PRODUCING ANTIGEN-BINDING PROTEINS AGAINST FOREIGN ANTIGENS

#18
20250207118
2025-06-26

HUMAN ALPHA-GALACTOSIDASE VARIANTS

#19
20250171757
2025-05-29

OPTIMIZED ENGINEERED MEGANUCLEASES HAVING SPECIFICITY FOR A RECOGNITION SEQUENCE IN THE HEPATITIS B VIRUS GENOME

#20
20250171558
2025-05-29

HUMAN IgG Fc DOMAIN VARIANTS WITH IMPROVED EFFECTOR FUNCTION

#21
20250154246
2025-05-15

NOVEL T CELL RECEPTORS AND IMMUNE THERAPY USING THE SAME

#22
20250137021
2025-05-01

METHODS OF PRODUCING NOR-OPIOID AND NAL-OPIOID BENZYLISOQUINOLINE ALKALOIDS

#23
20250101454
2025-03-27

COMPOSITION FOR TREATMENT OF SEPSIS BY REGULATING OLFR164

#24
20250098651
2025-03-27

A NON-HUMAN MAMMAL COMPRISING IN ITS GENOME AT LEAST TWO HUMAN LEUKOCYTE ANTIGEN (HLA) CLASS I ALLELES, METHODS OF MAKING SUCH MAMMAL AND USES THEREOF

#25
20250027054
2025-01-23

Compositions And Methods For Differentiation Of Human Pluripotent Stem Cells Into Desired Cell Types

#26
20240425600
2024-12-26

TRANSGENIC MICE WITH HUMANIZED MHC I AND IMMUNOGLOBLUIN HEAVY CHAIN GENES

#27
20240425599
2024-12-26

TRANSGENIC MICE WITH HUMANIZED MHC I AND IMMUNOGLOBLUIN HEAVY CHAIN GENES

#28
20240425596
2024-12-26

COMPOSITIONS OF PROGRAMMED DEATH RECEPTOR 1 (PD-1) ANTIBODIES AND METHODS OF OBTAINING THE COMPOSITIONS THEREOF

#29
20240409651
2024-12-12

OX40-Binding Polypeptides and Uses Thereof

#30
20240392313
2024-11-28

MAMMALIAN ARTIFICIAL CHROMOSOME VECTOR HAVING HUMAN IMMUNOGLOBULIN HEAVY CHAIN LOCUS COMPRISING MODIFIED D-REGION, AND CELL OR NON-HUMAN ANIMAL RETAINING THE VECTOR

#31
20240309101
2024-09-19

ANTI-CD25 ANTIBODY AGENTS

#32
20240293580
2024-09-05

Optimized RPE65 Promoter and Coding Sequences

#33
20240271158
2024-08-15

Circular RNA For Translation In Eukaryotic Cells

#34
20240271101
2024-08-15

METHOD FOR PRODUCING AN IMMUNOCONJUGATE

#35
20240263355
2024-08-08

mRNA display antibody library and methods

#36
20240251767
2024-08-01

ENGINEERED NON-HUMAN ANIMALS FOR PRODUCING ANTIBODIES

#37
20240239850
2024-07-18

VARIANT OF A BPIFB4 PROTEIN

#38
20240224963
2024-07-11

RECOMBINANT GENOME, AND NON-HUMAN MAMMALIAN CELL AND PRODUCTION METHOD THEREFOR AND USE THEREOF

#39
20240209379
2024-06-27

COMPOSITIONS AND METHODS FOR ENHANCING GENE EXPRESSION

#40
20240209059
2024-06-27

ANTI-KRAS-G12D T CELL RECEPTORS

#41
20240191250
2024-06-13

Methods of Treating Muscular Dystrophy

#42
20240190954
2024-06-13

ANTIBODY FOR BINDING TO INTERLEUKIN 4 RECEPTOR

#43
20240182579
2024-06-06

ANTI-PD-1 ANTIBODIES AND USES THEREOF

#44
20240182534
2024-06-06

VIRAL EXPRESSION CONSTRUCT COMPRISING A FIBROBLAST GROWTH FACTOR 21 (FGF21) CODING SEQUENCE

#45
20240175049
2024-05-30

LONG GERMLINE DH GENES AND LONG HCDR3 ANTIBODIES

#46
20240158807
2024-05-16

Circular RNA For Translation In Eukaryotic Cells

#47
20240130339
2024-04-25

RECOMBINANT GENOME, AND NON-HUMAN MAMMALIAN CELL AND PRODUCTION METHOD THEREFOR AND USE THEREOF

#48
20240084001
2024-03-14

BISPECIFIC ANTIBODIES AGAINST CEACAM5 AND CD47

#49
20240067746
2024-02-29

THERAPEUTIC ANTIBODIES

#50
20240035037
2024-02-01

TRANSPOSON-BASED VECTORS AND USES

#51
20240035011
2024-02-01

OPTIMIZED ENGINEERED MEGANUCLEASES HAVING SPECIFICITY FOR A RECOGNITION SEQUENCE IN THE HEPATITIS B VIRUS GENOME

#52
20240034777
2024-02-01

ANTI-TAU ANTIBODIES AND USES THEREOF

#53
20230348617
2023-11-02

CHIMERIC ANTIGEN RECEPTORS TARGETED TO PSCA

#54
20230332175
2023-10-19

TRANSGENIC RABBIT WITH COMMON LIGHT CHAIN

#55
20230329201
2023-10-19

CELLS AND NON-HUMAN ANIMALS ENGINEERED TO EXPRESS ADAR1 AND USES THEREOF

#56
20230322896
2023-10-12

AN ENGINEERED TWO-PART CELLULAR DEVICE FOR DISCOVERY AND CHARACTERISATION OF T-CELL RECEPTOR INTERACTION WITH COGNATE ANTIGEN

#57
20230295563
2023-09-21

TARGETED DISRUPTION OF T CELL AND/OR HLA RECEPTORS

#58
20230287119
2023-09-14

ANTI-CD3 ANTIBODY AND MOLECULES COMPRISING THE ANTIBODY

#59
20230257767
2023-08-17

Promoter of Hspa5 Gene

#60
20230148574
2023-05-18

GENETICALLY MODIFIED NON-HUMAN ANIMAL WITH HUMAN OR CHIMERIC CD38

#61
20230145413
2023-05-11

FAST-OFF RATE SERUM ALBUMIN BINDING FIBRONECTIN TYPE III DOMAINS

#62
20230133028
2023-05-04

TRANSGENIC MICE

#63
20230128188
2023-04-27

OX40-binding polypeptides and uses thereof

#64
20230105342
2023-04-06

METHOD FOR PRODUCING RECOMBINANT PROTEINS IN INSECTS

#65
20230104286
2023-04-06

Methods of producing nor-opioid and nal-opioid benzylisoquinoline alkaloids

#66
20230092556
2023-03-23

IN VIVO USE OF CHONDROITINASE AND/OR HYALURONIDASE TO ENHANCE DELIVERY OF AN AGENT

#67
20230087790
2023-03-23

BINDING MOLECULES SPECIFIC FOR CLAUDIN 18.2, COMPOSITONS AND METHODS THEREOF, FOR TREATMENT OF CANCER AND OTHER DISEASES

#68
20230079439
2023-03-16

Compositions and Methods for Enhancing Beta Cell Maturation, Health and Function

#69
20230074894
2023-03-09

AAV VARIANTS WITH HOST ANTIBODY ESCAPE CAPABILITIES AND ALTERED TISSUE TARGETING PROPERTIES

#70
20230064378
2023-03-02

Human interleukin-4 receptor alpha antibodies

#71
20230057150
2023-02-23

HUMAN IgG Fc DOMAIN VARIANTS WITH IMPROVED EFFECTOR FUNCTION

#72
20230052256
2023-02-16

NOVEL ANTI-FGFR2B ANTIBODIES

#73
20230050306
2023-02-16

Circular RNA for translation in eukaryotic cells

#74
20230048658
2023-02-16

DIRECT SELECTION OF CELLS EXPRESSING HIGH LEVELS OF HETEROMERIC PROTEINS USING GLUTAMINE SYNTHETASE INTRAGENIC COMPLEMENTATION VECTORS

#75
20230030032
2023-02-02

METHODS AND SYSTEMS FOR TREATING OR PREVENTING PREGNANCY-RELATED HYPERTENSIVE DISORDERS

#76
20230029386
2023-01-26

METHODS OF DETECTING ALLOANTIBODIES TO HLA CLASS II ANTIGENS

#77
20230029363
2023-01-26

PRODUCTION OF RECOMBINANT PROTEINS USING FAH AS THE SELECTION MARKER

#78
20230021388
2023-01-26

ANTI-ROR1 ANTIBODIES AND COMPOSITIONS

#79
20220403042
2022-12-22

Therapeutic antibodies

#80
20220356458
2022-11-10

Human alpha-galactosidase variants

#81
20220325249
2022-10-13

PLATFORM FOR THE INDUCTION & MAINTENANCE OF GROUND STATE PLURIPOTENCY

#82
20220259274
2022-08-18

Methods and compositions related to recombinant NEIL2

#83
20220251205
2022-08-11

Compositions of programmed death receptor 1 (PD-1) antibodies and methods of obtaining the compositions thereof

#84
20220243243
2022-08-04

EXPRESSION OF PRODUCTS FROM NUCLEIC ACID CONCATEMERS

#85
20220226435
2022-07-21

Ciliary Neurotrophic Factor Receptor Ligands and Methods of Using the Same

#86
20220213221
2022-07-07

ANTI-RHO GTPASE CONFORMATIONAL SINGLE DOMAIN ANTIBODIES AND USES THEREOF

#87
20220204596
2022-06-30

ANTIBODIES WITH ENGINEERED CH2 DOMAINS, COMPOSITIONS THEREOF AND METHODS OF USING THE SAME

#88
20220177606
2022-06-09

MICE THAT MAKE VL BINDING PROTEINS

#89
20220169686
2022-06-02

Variant of a BPIFB4 protein

#90
20220167600
2022-06-02

METHODS FOR PRODUCING ANTIGEN-BINDING PROTEINS AGAINST FOREIGN ANTIGENS

#91
20220153824
2022-05-19

ANTI-C5A ANTIBODIES AND USES THEREOF

#92
20220127639
2022-04-28

NON-HLA MATCHED HUMANIZED NSG MOUSE MODEL WITH PATIENT-DERIVED XENOGRAFT

#93
20220127638
2022-04-28

NON-HLA MATCHED HUMANIZED NSG MOUSE MODEL WITH PATIENT-DERIVED XENOGRAFT

#94
20220112518
2022-04-14

MSBI SEQUENCES AS AN EARLY MARKER FOR THE FUTURE DEVELOPMENT OF CANCER AND DISEASES OF THE CNS AND AS A TARGET FOR THE TREATMENT AND PREVENTION OF THESE DISEASES

#95
20220090125
2022-03-24

TRANSGENIC MOUSE EXPRESSING COMMON HUMAN LIGHT CHAIN

#96
20220089677
2022-03-24

Anti-KRAS-G12D T cell receptors

#97
20220056427
2022-02-24

Polynucleotides encoding optimized engineered meganucleases having specificity for a recognition sequence in the Hepatitis B virus genome

#98
20220056422
2022-02-24

APPLICATION OF UTX GENE IN PREPARATION OF DRUGS FOR PREVENTING OR TREATING LIPID DISEASES

#99
20220042036
2022-02-10

METHODS AND COMPOSITIONS FOR PREPARING SURFACTANT PROTEIN D (SP-D)

#100
20220025395
2022-01-27

Circular RNA for translation in eukaryotic cells

#101
20220017918
2022-01-20

Synthesis of Non-Native Proteins in Bombyx Mori by Modifying Sericin Expression

#102
20220017917
2022-01-20

Synthesis of High Molecular Weight Proteins Using Inteins

#103
20220017575
2022-01-20

AAVrh.10 variants with host antibody escape capabilities and altered tissue targeting properties

#104
20220016236
2022-01-20

Recombinant porcine parvovirus antigenic protein and use thereof

#105
20210403944
2021-12-30

Circular RNA for translation in eukaryotic cells

#106
20210400962
2021-12-30

Insect toxin delivery mediated by a densovirus coat protein

#107
20210400936
2021-12-30

METHODS, COMPOSITIONS AND SYSTEMS FOR PRODUCTION OF RECOMBINANT SPIDER SILK POLYPEPTIDES

#108
20210395699
2021-12-23

Compositions and methods for differentiation of human pluripotent stem cells into desired cell types

#109
20210388079
2021-12-16

NOVEL T CELL RECEPTORS AND IMMUNE THERAPY USING THE SAME

#110
20210380973
2021-12-09

TCR libraries

#111
20210363540
2021-11-25

Circular RNA for translation in eukaryotic cells

#112
20210317468
2021-10-14

SYNTHESIS AND STRUCTURE OF HIGH POTENCY RNA THERAPEUTICS

#113
20210310023
2021-10-07

Method for preparing fish skin mucous gland bioreactor and application thereof

#114
20210300988
2021-09-30

Anti-KRAS-G12D T cell receptors

#115
20210269823
2021-09-02

GENETICALLY-MODIFIED POULTRY EGG

#116
20210261948
2021-08-26

mRNA display antibody library and methods

#117
20210253673
2021-08-19

COMPOSITIONS AND METHODS FOR INHIBITING ENDOGENOUS IMMUNOGLOBULIN GENES AND PRODUCING TRANSGENIC HUMAN IDIOTYPE ANTIBODIES

#118
20210251202
2021-08-19

NON-HUMAN ANIMALS CAPABLE OF DH-DH REARRANGEMENT IN THE IMMUNOGLOBULIN HEAVY CHAIN CODING SEQUENCES

#119
20210251201
2021-08-19

Non-human animals having a humanized signal-regulatory protein gene

#120
20210230297
2021-07-29

Antibodies useful for detection of human carcinoma antigen

#121
20210213142
2021-07-15

GENE THERAPIES FOR NEURODEGENERATIVE DISORDERS TARGETING GANGLIOSIDE BIOSYNTHETIC PATHWAYS

#122
20210198688
2021-07-01

Circular RNA for translation in eukaryotic cells

#123
20210195877
2021-07-01

Non-human animals expressing exogenous terminal deoxynucleotidyltransferase

#124
20210189403
2021-06-24

Expression from transposon-based vectors and uses

#125
20210171658
2021-06-10

Anti-rho GTPase conformational single domain antibodies and uses thereof

#126
20210163628
2021-06-03

MICE THAT MAKE VL BINDING PROTEINS

#127
20210095311
2021-04-01

MOUSE ARTIFICIAL CHROMOSOME VECTOR AND USE THEREOF

#128
20210087596
2021-03-25

Methods of producing nor-opioid and nal-opioid benzylisoquinoline alkaloids

#129
20210079088
2021-03-18

Antibody for binding to interleukin 4 receptor

#130
20210059229
2021-03-04

ADAM6 KNOCKIN MICE

#131
20210054084
2021-02-25

Anti-CD25 antibody agents

#132
20210051929
2021-02-25

GENETICALLY MODIFIED NON-HUMAN ANIMALS FOR GENERATING THERAPEUTIC ANTIBODIES AGAINST PEPTIDE-MHC COMPLEXES, METHODS OF MAKING AND USES THEREOF

#133
20210047420
2021-02-18

Anti-CD25 for tumour specific cell depletion

#134
20210040221
2021-02-11

Anti-CD25 for tumour specific cell depletion

#135
20210040194
2021-02-11

Nucleic acids encoding bispecific anti-VEGF and anti-ANG2 antibodies and uses thereof

#136
20210037797
2021-02-11

INDUCIBLE DISEASE MODELS METHODS OF MAKING THEM AND USE IN TISSUE COMPLEMENTATION

#137
20210032311
2021-02-04

NON-HUMAN GENE-EDITED MAMMAL, PROTEIN CRUDE EXTRACT SEPARATED FROM CONNECTIVE TISSUE OF NON-HUMAN GENE-EDITED MAMMAL, METHOD FOR PROTEIN CRUDE EXTRACT AND USES OF PROTEIN CRUDE EXTRACT

#138
20210029978
2021-02-04

NON-HUMAN ANIMALS HAVING AN ENGINEERED IMMUNOGLOBULIN LAMBDA LIGHT CHAIN LOCUS

#139
20210024622
2021-01-28

Anti-Tau antibodies and uses thereof

#140
20210017253
2021-01-21

NUCLEIC ACID MOLECULES AND APPLICATIONS THEREOF IN PREPARING HUMAN SINGLE-DOMAIN ANTIBODY

#141
20210017244
2021-01-21

Viral vector suitable for gene therapy encoding a variant of a BPIFB4 protein

#142
20210009704
2021-01-14

Anti-CD25 for tumour specific cell depletion

#143
20210009703
2021-01-14

Anti-CD25 for tumour specific cell depletion

#144
20210009702
2021-01-14

Anti-CD25 for tumour specific cell depletion

#145
20210009699
2021-01-14

Anti-CD25 antibody agents

#146
20210009670
2021-01-14

Nucleic acid molecules and applications thereof in human antibody

#147
20210008194
2021-01-14

MDCK suspension cell lines in serum-free, chemically-defined media for vaccine production

#148
20200407747
2020-12-31

METHODS, COMPOSITIONS AND CELLS FOR PREPARING SURFACTANT PROTEIN D (SP-D)

#149
20200407454
2020-12-31

Anti-CD25 antibody agents

#150
20200392554
2020-12-17

EXPRESSION OF PRODUCTS FROM NUCLEIC ACID CONCATEMERS

#151
20200392513
2020-12-17

A METHOD FOR GENOME EDITING IN A HOST CELL

#152
20200392473
2020-12-17

NOVEL CRISPR ENZYMES AND SYSTEMS

#153
20200325463
2020-10-15

Cellobiohydrolase variants and polynucleotides encoding same

#154
20200308300
2020-10-01

Chimeric antigen receptors targeted to PSCA

#155
20200283505
2020-09-10

Fast-off rate serum albumin binding fibronectin type III domains

#156
20200267951
2020-08-27

GENERATION OF HEAVY-CHAIN ONLY ANTIBODIES IN TRANSGENIC ANIMALS

#157
20200255514
2020-08-13

Antibody for binding to interleukin 4 receptor

#158
20200247869
2020-08-06

Anti-KRAS-T cell receptors

#159
20200229408
2020-07-23

Gene-modified mouse expressing human GPC3 polypeptide

#160
20200207857
2020-07-02

Binding molecules specific for claudin 18.2, compositions and methods thereof, for the treatment of cancer and other diseases

#161
20200205384
2020-07-02

Transgenic Animals

#162
20200199563
2020-06-25

Human alpha-galactosidase variants

#163
20200187468
2020-06-18

Non-human animals having a humanized signal-regulatory protein gene

#164
20200179535
2020-06-11

Optimized RPE65 promoter and coding sequences

#165
20200157236
2020-05-21

Anti-ALK antibodies and methods for use thereof

#166
20200157217
2020-05-21

Anti-CD3 antibodies and methods of making and using thereof

#167
20200157212
2020-05-21

Anti-ROBO2 antibodies, compositions, methods and uses thereof

#168
20200148772
2020-05-14

Anti-PD-L1 nanobody, coding sequence and use thereof

#169
20200148754
2020-05-14

Anti-C5a antibodies and uses thereof

#170
20200147137
2020-05-14

COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER

#171
20200140540
2020-05-07

T cell receptors and immune therapy using the same

#172
20200140527
2020-05-07

Human monoclonal antibodies to human endogenous retrovirus K envelope (HERV-K) and use thereof

#173
20200123252
2020-04-23

Bispecific antibodies against CEACAM5 and CD47

#174
20200115460
2020-04-16

Anti-IGF-I receptor antibodies, encoding nucleic acid molecules and methods of using said antibodies

#175
20200115454
2020-04-16

Anti-PD-1 antibodies and uses thereof

#176
20200115432
2020-04-16

AN ENGINEERED TWO-PART CELLULAR DEVICE FOR DISCOVERY AND CHARACTERISATION OF T-CELL RECEPTOR INTERACTION WITH COGNATE ANTIGEN

#177
20200109369
2020-04-09

INNOVATIVE PREPARATION PROCESS FOR BMP-2 STEM CELLS

#178
20200102361
2020-04-02

VIRAL EXPRESSION CONSTRUCT COMPRISING A FIBROBLAST GROWTH FACTOR 21 (FGF21) CODING SEQUENCE

#179
20200102358
2020-04-02

METHODS AND COMPOSITIONS RELATED TO RECOMBINANT NEIL2

#180
20200101016
2020-04-02

COMPOSITIONS AND METHODS FOR PRODUCING EXOSOME LOADED THERAPEUTICS FOR TREATING CARDIOVASCULAR DISEASE

#181
20200100479
2020-04-02

Recombinant adenovirus-based interferon biotherapeutics in swine

#182
20200080106
2020-03-12

Circular RNA for translation in eukaryotic cells

#183
20200080090
2020-03-12

SELF-LIMITING CAS9 CIRCUITRY FOR ENHANCED SAFETY (SLICES) PLASMID AND LENTIVIRAL SYSTEM THEREOF

#184
20200072831
2020-03-05

METHODS OF DETECTING ALLOANTIBODIES TO HLA CLASS II ANTIGENS

#185
20200056202
2020-02-20

ANIMAL MODELS AND THERAPEUTIC MOLECULES

#186
20200055946
2020-02-20

OX40-binding polypeptides and uses thereof

#187
20200024580
2020-01-23

APPLICATION OF UTX GENE IN PREPARATION OF DRUGS FOR PREVENTING OR TREATING LIPID DISEASES

#188
20200002723
2020-01-02

MSBI SEQUENCES AS AN EARLY MARKER FOR THE FUTURE DEVELOPMENT OF CANCER AND DISEASES OF THE CNS AND AS A TARGET FOR THE TREATMENT AND PREVENTION OF THESE DISEASES

#189
20190390170
2019-12-26

METHODS FOR MODULATING PRODUCTION PROFILES OF RECOMBINANT PROTEINS

#190
20190380316
2019-12-19

NON-HUMAN ANIMALS CAPABLE OF ENGINEERED DH-DH REARRANGEMENT AND USES THEREOF

#191
20190375824
2019-12-12

VHH antibody

#192
20190374576
2019-12-12

VIRAL METHODS OF T CELL THERAPY

#193
20190367632
2019-12-05

Therapeutic antibodies

#194
20190360017
2019-11-28

Recombinant protein production system

#195
20190359945
2019-11-28

METHOD FOR PRODUCING AN IMMUNOCONJUGATE

#196
20190359712
2019-11-28

Anti-CD3 antibody and molecules comprising the antibody

#197
20190345203
2019-11-14

AAVrh.10 variants with host antibody escape capabilities and altered tissue targeting properties

#198
20190338269
2019-11-07

FACTOR X VARIANTS

#199
20190338263
2019-11-07

Optimized engineered meganucleases having specificity for a recognition sequence in the Hepatitis B virus genome

#200
20190338026
2019-11-07

Anti-leukocyte-associated immunoglobulin-like receptor 1 (LAIR1) monoclonal antibodies and method of use thereof to treat cancer

#201
20190335726
2019-11-07

GENETICALLY MODIFIED CELLS, TISSUES, AND ORGANS FOR TREATING DISEASE

#202
20190330601
2019-10-31

A CELL-BASED ARRAY PLATFORM

#203
20190328837
2019-10-31

Ciliary neurotrophic factor receptor ligands and methods of using the same

#204
20190328783
2019-10-31

A METHOD OF ENGINEERING PRODRUG-SPECIFIC HYPERSENSITIVE T-CELLS FOR IMMUNOTHERAPY BY GENE EXPRESSION

#205
20190322752
2019-10-24

Anti-CD25 antibody agents

#206
20190321403
2019-10-24

Engineered B cells and related compositions and methods

#207
20190320630
2019-10-24

Transgenic animal for production of antibodies having minimal CDRs

#208
20190314491
2019-10-17

Recombinant RSV antigens, nucleic acid molecules encoding the antigens, and vaccine compositions comprising the same

#209
20190309059
2019-10-10

IL-13 antibody and preparation method and use thereof

#210
20190300621
2019-10-03

HUMAN IgG Fc DOMAIN VARIANTS WITH IMPROVED EFFECTOR FUNCTION

#211
20190300613
2019-10-03

Anti-CD25 antibody agents

#212
20190292263
2019-09-26

GENETICALLY MODIFIED NON-HUMAN ANIMALS FOR GENERATING THERAPEUTIC ANTIBODIES AGAINST PEPTIDE-MHC COMPLEXES, METHODS OF MAKING AND USES THEREOF

#213
20190290693
2019-09-26

PDL1 block CAR-T transgenic vector for suppressing immune escape, preparation method thereof, and application of the same

#214
20190284287
2019-09-19

Anti-CD25 antibody agents

#215
20190284279
2019-09-19

BISPECIFIC ANTIBODY BINDING TO HUMAN CD19 AND CD3

#216
20190284263
2019-09-19

IN VIVO USE OF CHONDROITINASE AND/OR HYALURONIDASE TO ENHANCE DELIVERY OF AN AGENT

#217
20190270800
2019-09-05

Production cell line enhancers

#218
20190264195
2019-08-29

mRNA display antibody library and methods

#219
20190263929
2019-08-29

Antibodies useful for detection of human carcinoma antigen

#220
20190256840
2019-08-22

BINDING MEMBERS WITH ALTERED DIVERSITY SCAFFOLD DOMAINS

#221
20190256590
2019-08-22

T cell receptors and immune therapy using the same

#222
20190254264
2019-08-22

Human antibody-producing non-human animal and method for preparing human antibodies using same

#223
20190248900
2019-08-15

Antibody to programmed cell death 1 (PD-1) and use thereof

#224
20190241907
2019-08-08

Promoter of Hspa5 gene

#225
20190239513
2019-08-08

Insect toxin delivery mediated by a densovirus coat protein

#226
20190234959
2019-08-01

SYSTEM AND METHOD FOR CHARACTERIZING DRUG PRODUCT IMPURITIES

#227
20190227063
2019-07-25

METHODS AND COMPOSITIONS FOR T-CELL EPITOPE SCREENING

#228
20190218520
2019-07-18

Platform for the induction and maintenance of ground state pluripotency

#229
20190209612
2019-07-11

Method of preparing T cells with increased activity

#230
20190202904
2019-07-04

Synthetic antibodies against VEGF and their uses

#231
20190194686
2019-06-27

HOST CELLS WITH ENHANCED PROTEIN EXPRESSION EFFICIENCY AND USES THEREOF

#232
20190194638
2019-06-27

Fusion proteins comprising an aldolase enzyme joined to a maltose binding protein

#233
20190194308
2019-06-27

Anti-VEGF-A and anti-ANG2 antibodies and uses thereof

#234
20190185863
2019-06-20

Expression from transposon-based vectors and uses

#235
20190185575
2019-06-20

Monoclonal antibody against MELK and utilization thereof

#236
20190177416
2019-06-13

Anti-PD-L1 nanobody, coding sequence and use thereof

#237
20190177414
2019-06-13

Anti-CTLA4 antibodies

#238
20190177408
2019-06-13

ANTIBODY FOR BINDING TO INTERLEUKIN 4 RECEPTOR

#239
20190177404
2019-06-13

Antibodies with engineered CH2 domains, compositions thereof and methods of using the same

#240
20190177395
2019-06-13

Anti-KRAS-G12D T cell receptors

#241
20190174731
2019-06-13

GENE-MODIFIED NON-HUMAN ANIMAL EXPRESSING HUMAN GPC3 POLYPEPTIDE

#242
20190169294
2019-06-06

Anti-LAG-3 antibody

#243
20190169277
2019-06-06

Modified anti-tenascin antibodies and methods of use

#244
20190169270
2019-06-06

COMPOSITIONS AND METHODS FOR INHIBITING ENDOGENOUS IMMUNOGLOBULIN GENES AND PRODUCING TRANSGENIC HUMAN IDIOTYPE ANTIBODIES

#245
20190161730
2019-05-30

COMPOSITIONS AND METHODS RELATED TO THERAPEUTIC CELL SYSTEMS EXPRESSING EXOGENOUS RNA

#246
20190161555
2019-05-30

Bispecific Antibodies Directed Against OX40 and a Tumor-Associated Antigen

#247
20190161544
2019-05-30

Anti-human interleukin-17A monoclonal antibody

#248
20190161534
2019-05-30

ANTI-GALACTAN II MONOCLONAL ANTIBODIES TARGETING KLEBSIELLA PNEUMONIAE

#249
20190144900
2019-05-16

Methods of producing nor-opioid and nal-opioid benzylisoquinoline alkaloids

#250
20190144543
2019-05-16

Anti-PD-1 antibodies and uses thereof

#251
20190141967
2019-05-16

Transgenic animal for production of antibodies having minimal CDRs

#252
20190127757
2019-05-02

Long germline DH genes and long HCDR3 antibodies

#253
20190127452
2019-05-02

Direct selection of cells expressing high levels of heteromeric proteins using glutamine synthetase intragenic complementation vectors

#254
20190124895
2019-05-02

Non-human animals having a humanized signal-regulatory protein gene

#255
20190119378
2019-04-25

Humanized anti-rage antibody

#256
20190116768
2019-04-25

Methods, compositions and systems for production of recombinant spider silk polypeptides

#257
20190112365
2019-04-18

Anti-Tau antibodies and uses thereof

#258
20190112364
2019-04-18

Anti-tau antibodies and uses thereof

#259
20190106463
2019-04-11

Engineered polypeptides for antigen delivery

#260
20190100771
2019-04-04

Transgenic rabbit with common light chain

#261
20190093124
2019-03-28

Transgenic cloned piglet expressing human proinsulin and method of producing the same

#262
20190085309
2019-03-21

Cellobiohydrolase variants and polynucleotides encoding same

#263
20190082665
2019-03-21

TRANSGENE EXPRESSION IN AVIANS

#264
20190078099
2019-03-14

CELL LINE FOR RECOMBINANT PROTEIN AND/OR VIRAL VECTOR PRODUCTION

#265
20190071694
2019-03-07

Methods and compositions for preparing surfactant protein D (SP-D)

#266
20190071693
2019-03-07

Methods, compositions and cells for preparing surfactant protein D (SP-D)

#267
20190048333
2019-02-14

TCR libraries

#268
20190048090
2019-02-14

Agents binding specifically to human cadherin-17, human cadherin-5, human cadherin-6 and human cadherin-20 RGD motif

#269
20190045761
2019-02-14

INDUCIBLE DISEASE MODELS METHODS OF MAKING THEM AND USE IN TISSUE COMPLEMENTATION

#270
20190040119
2019-02-07

Method for producing antibody

#271
20190010515
2019-01-10

Genetically modified chicken egg with an exogenous sequence knocked into the ovalbumin gene

#272
20190002556
2019-01-03

T cell receptors and immune therapy using the same

#273
20180362926
2018-12-20

Targeted disruption of T cell and/or HLA receptors

#274
20180362666
2018-12-20

Transgenic mice

#275
20180340187
2018-11-29

Methods of treating muscular dystrophy

#276
20180338479
2018-11-29

Transgenic animal for production of antibodies having minimal CDRS

#277
20180320128
2018-11-08

METHODS FOR MODULATING PRODUCTION PROFILES OF RECOMBINANT PROTEINS

#278
20180319879
2018-11-08

Anti-canine TARC antibody used for treatment and diagnosis of canine atopic dermatitis

#279
20180311337
2018-11-01

MDCK suspension cell lines in serum-free, chemically-defined media for vaccine production

#280
20180298112
2018-10-18

Animal models and therapeutic molecules

#281
20180295822
2018-10-18

High-throughput mouse model for optimizing antibody affinities

#282
20180295821
2018-10-18

Transgenic Animals

#283
20180282761
2018-10-04

Chimaeric Surrogate Light Chains (SLC) Comprising Human VpreB

#284
20180265892
2018-09-20

Genetically engineered larvae for wound healing

#285
20180265890
2018-09-20

EFFICIENT AND SAFE TRANSPOSON INTEGRATION SYSTEM AND USE THEREOF

#286
20180258158
2018-09-13

Fast-off rate serum albumin binding fibronectin type III domains

#287
20180251735
2018-09-06

Compositions and methods for differentiation of human pluripotent stem cells into desired cell types

#288
20180214573
2018-08-02

Gene therapies for neurodegenerative disorders targeting ganglioside biosynthetic pathways

#289
20180213755
2018-08-02

Human IL-15-secreting immunodeficient mouse

#290
20180192623
2018-07-12

Non-human animal having human CD3 gene substituted for endogenous CD3 gene

#291
20180187210
2018-07-05

Non-HLA matched humanized NSG mouse model with patient-derived xenograft

#292
20180171340
2018-06-21

Compositions and methods for enhancing gene expression

#293
20180141972
2018-05-24

NATIVE PROTEIN PURIFICATION TECHNOLOGY

#294
20180139941
2018-05-24

Non-human animals having a humanized signal-regulatory protein gene

#295
20180125043
2018-05-10

Non-human animals having an engineered immunoglobulin Λ light chain locus

#296
20180021458
2018-01-25

Optimized RPE65 promoter and coding sequences

#297
20170355740
2017-12-14

METHODS OF USING FIBROBLAST GROWTH FACTOR (FGF) 1 WITH MUTATION IN THE HEPARIN BINDING DOMAIN AND METHODS TO REDUCE BLOOD GLUCOSE

#298
20170347633
2017-12-07

Non-human animals expressing exogenous terminal deoxynucleotidyltransferase

#299
20170342422
2017-11-30

Sequence variants

#300
20170339929
2017-11-30

HCO32 and HCO27 and related examples